BRITISH COLUMBIA CENTRE for EXCELLENCE in HIV/AIDS

Julio Montaner MD, DSc(hon), FRCPC, FCCP, FRSC, OBCDirector, BC-Centre for Excellence in HIV/AIDS, Providence Health Care

Professor of Medicine and Head, Division of AIDS, University of British ColumbiaPast-President, International AIDS Society

To Download the Workshop’s Report go to: www.treatmentaspreventionworkshop.org/2012-workshop/

Scientific Advisory Committee Julio S.G. Montaner, ChairElly Katabira, Co-ChairBertrand AudoinCurt BeckwithPedro CahnYvette CalderonChinazo CunninghamCarlos Del RioWafaa El-SadrAlison EndGeoff GarnettReuben Granich

Mark HarringtonGregory Kirk

Ann KurthViviane Dias Lima

Jacqueline Ying-Ru LoRob Lyerla

Jean-Michel MolinaJacques NormandMariangela Simao

Papa Salif SowBrian Williams

Zunyou Wu

Reported AIDS Rate in British Columbia

1983 - 2009

BC: Number of deaths (all-cause)

Updated from Montaner et al, Lancet 2010

Association between HAART Expansion and HIV New Diagnoses

British Columbia, 1996 - 2011

Patients Currently on HAARTNew HIV DiagnosesNew HIV Diagnoses - IDU

Canada: HIV+ tests by region by year (rate per 100,000 pop)

Hogg et al, CAHR, 2012

000

005

010

015

020British Columbia (-0.90, <0.0001)Alberta (0.12, 0.68)Ontario (0.04, 0.90)Quebec (-0.45, 0.11)Atlantic (-0.43, 0.13)

Vertical Transmission of HIVCanada, 1990 - 2004

Granich et al

Lives Saved (x 1,000) U$A Billions

Treatment 2.0:A new prevention-treatment paradigm in the global response to HIV/AIDS- UNGASSNew York - 9 June 2010

“The Environment and Disease: Association or Causation - A Case for Action”

All Scientific work is incomplete – whether it be observational or experimental. All scientific work is liable to be upset or modified by advancing knowledge. That does not confer upon us a freedom to ignore the knowledge we already have, or to postpone the action that it appears to demand at a given time.Austin Bradford Hill (1897-1991) British epidemiologist best known for

his research with Richard Doll, which linked smoking with lung cancer. He was also widely acknowledged as the world’s leading medical statistician and a pioneer in the use of RCTs.