tribute. The book opens with a short andelliptical biography of Mosteller by JohnTukey, who notes along the way Mosteller'sinterests in such works as the Annals ofMathematical Statistics, the Kinsey Report,and the Federalist papers. Chapter 2, towhich subsequent contributions make muchreference, is a bibliography of Mosteller'spublications, categorized as books to whichhe has made a contribution (n = 56), "pa-pers" he has published (n = 182), "miscel-laneous" (n = 36), and reviews (n = 25).William Kruskal then provides some obser-vations on Mosteller as a "scientific general-ist," and more technical aspects of his workare addressed by Persi Diaconis and ErichLehmann, who discuss systematic statistics,slippage tests, mathematical learning theory,and number theory, and by Stephen Fien-berg, who discusses Mosteller's concernsregarding statistical methodology and itsapplication in other fields. "Fred as educa-tor" is the title of a contribution by JudithTanur, who notes that Mosteller was (statis-tically) assessing new teaching techniqueseven in the introductory statistics course hetaught just before retirement, and in "Fredat Harvard" Fienberg and Hoaglin marshalthe assistance of some 20 associates of Mos-teller's to provide an account of his 40 yearsthere. A collection of photographs precedesa final chapter edited by Hoaglin, consistingof book reviews of a sort-assessments, expostfacto in some cases by over 40 years, ofworks that have borne Mosteller's name.The assessments are friendly, and, overall,humor and a sense of statistics as being"fun" pervade the volume.-K.L.

Launching the Antibiotic Era. Personal Ac-counts of the Discovery and Use of the FirstAntibiotics. CAROL L. MOBERG and ZANVIL A.CoHN, Eds. Rockefeller University Press, NewYork, 1990. xii, 97 pp., illus. $25. From a sym-posium, New York, Oct. 1989.

A key event in the "launching of theantibiotic era" was Rene Dubos's discovery,in 1939, of gramicidin, "the first antimicrobialagent to be obtained from natural sourcesthrough rational pursuit." This retrospectivevolume, stemming from a symposium com-memorating that event, brings together es-says by some ofthose who were active in theearly developments leading to effective anti-biotic therapy. The volume opens with anintroduction by Joshua Lederberg that in-cludes an appreciation of Dubos's 1945treatise The Bacterial Cell. Rollin Hotchkiss,who participated in the effort to purifygramicidin, then offers his own recollec-tions, noting that prior to the appearance ofsulfanilamide in 1937 the dominant ap-proach to chemotherapy of bacterial disease

1624

had been through the use of toxic agentsthat had to be rendered less harmful to theirrecipients by "artful chemical group substi-tution or modification" and explaining therelevance of soil microbiology (an early in-terest of Dubos's) to the work on antibiot-ics. The much-written-about early history ofpenicillin is the focus of the next two con-tributions, by Edward Abraham and Nor-man Heatley, both of whom worked withHoward Florey. Among other matters,Abraham describes the survey of antimicro-bial agents undertaken by Florey and ErnestChain and discusses his own discovery, withGuy Newton (1953), of cephalosporin C;Heatley's essay includes an account of thedifficulties of obtaining the needed culturevessels and other equipment during war-time, as well as some comments on thecontroversy surrounding the contributionsof Alexander Fleming. Shifting from thelaboratory to the field, the next chapter is anaccount by Theodore Woodward of thesearch, in collaboration with the late JosephSmadel, for a cure (chloramphenicol) fortyphus and typhoid fever, an effort centeredin Malaya in the years following World WarII. In the next chapter George Mackanessdescribes how his work with mononuclearphagocytes, under Florey, led him to be-come involved in the development of iso-niazid as a therapy for tuberculosis. BernardDavis, who early in his career also wasengaged in tuberculosis research, providesan account of that work in the context of adiscussion of microbiological research moregenerally and of Dubos's research style.Among the matters he comments on are the"macho" risk-taking attitude that prevailedin research on infectious diseases, Dubos'sonetime skepticism regarding the promise ofantibiotics, and his own initial skepticismconcerning some of the early work on drugresistance. All the authors provide somereminiscences of Dubos or comment on hiswork, and in an epilogue to the book CarolMoberg discusses him in his capacity as a"friend of the good earth," referring to hislast writings on human ecology. Each of themain chapters includes a brief reference list,and the book contains a number of photo-graphs and other illustrations.-K.L.

Books ReceivedBeat Science Writing. Readings and Insights. Rob-

ert Gannon, Ed. Oryx, Phoenix, AZ, 1991. vi, 194 pp.Paper, $19.95. Selections by 12 writers who have wonawards, with brief commentary by the editor.Beyond Belief. Randomness, Prediction and Expla-

nation in Science. John L. Casti and Anders Karlqvist,Eds. CRC, Boca Raton, FL, 1991. xii, 334 pp., illus.$39.95. From a workshop, Abisko, Sweden, May 1989.Current Issues In Condensed Matter Spectrosco-

py. A. M. Stoneham, Ed. Hilger, Philadelphia, PA, 1990(distributor, American Institute of Physics, New York).

xii, 317 pp., illus. Paper, $50. Current Issues in SolidState Science.Development According to Parents. The Nature,

Sources, and Consequences of Parents' Ideas. JacquelineJ. Goodnow and W. Andrew Collins. Erlbaum, Hills-dale, NJ, 1990. viii, 190 pp. $36; paper, $17.50. Essaysin Developmental Psychology.

Diet, Uffe-style, and Mortality In China. A Study ofthe Characteristics of 65 Chinese Counties. Chen Junshiet al. Oxford University Press, Oxford, U.K., CornellUniversity Press, Ithaca, NY, and People's Medical,Beijing, P.R.C., 1990. xviii, 894 pp., illus. $172.50.The Explorations of Antarctica. The Last Unspoilt

Continent. G. E. Fogg and David Smith. Cassell, Lon-don, 1990 (U.S. distributor, Sterling, New York). 224pp., illus. $24.95.Fast-Scan Magnetic Resonance. Principles and

Applications. Felix W. Wehrli. Raven, New York, 1990.xii, 164 pp., illus. $45. Reprinted from Magnetic Reso-nance Quarterly, vol. 6, no. 3 (1990).Human Change Processes. The Scientific Founda-

tions of Psychotherapy. Michael J. Mahoney. BasicBooks, New York, 1991. xiv, 590 pp., illus. $45.A Journey Into Gravity and Spacetime. John

Archibald Wheeler. Scientific American Library, NewYork, 1990 (distributor, Freeman, New York). xiv, 257pp., illus. $32.95.Knowing and Remembering in Young Children.

Robyn Fivush and Judith A. Hudson, Eds. CambridgeUniversity Press, New York, 1991. x, 354 pp., illus.$39.50. Emory Symposia in Cognition, 3. From aconference, Atlanta, GA, Oct. 1987.Knowledge and Inference. Makoto Nagao. Aca-

demic Press, San Diego, CA, 1990. xvi, 304 pp., illus.$42.50. Translated from the Japanese edition (Tokyo,1988) by Richard Weyrauch and Yasuko Kitajima.Laboratory Experiments for Introduction to

Chemistry. T. R. Dickson, 6th ed. Wiley, New York,1991. xii, 241 pp., illus. Paper, $22.95.Prosperity without Pollution. The Prevention Strat-

egy for Industry and Consumers. Joel S. Hirschhorn andKirsten U. Oldenburg. Van Nostrand Reinhold, NewYork, 1990, xiv, 386 pp., illus. Paper, $19.95.Recombinant DIfA Technology and Applica-

tions. Ales Prokop, Rakesh K. Bajpai, and Chester S.Ho. McGraw-Hill, New York, 1991. xvi, 619 pp., illus.$49.50.

Risk Assessment in Genetic Engineering. MorrisA. Levin and Harlee S. Strauss. McGraw-Hill, NewYork, 1991. xii, 404 pp., illus. $39.95. McGraw-HillEnvironmental Biotechnology Series.Saving the Mediterranean. The Politics of Interna-

tional Environmental Cooperation. Peter M. Haas. Co-lumbia University Press, New York, 1990. xxviii, 303pp., illus. $42. Political Economy of InternationalChange.

Sweetiners. Discovery, Molecular Design, andChemoreception. D. Eric Walters, Frank T. Orthoefer,and Grant E. Dubois, Eds. American Chemical Society,Washington, DC, 1991. x, 333 pp., illus. $79.95. ACSSymposium Series, 450. From a symposium, Boston,MA, April 1990.

Tell Me A Story. A New Look at Real and ArtificialMemory. Roger C. Schank. Scribner's (Macmillan), NewYork, 1990. xvi, 253 pp., illus. $19.95.The Telling Image. The Changing Balance Between

Pictures and Words in a Technological Age. DuncanDavies, Diana Bathurst, and Robin Bathurst. Clarendon(Oxford University Press), New York, 1990. xviii, 166pp., illus., + plates. $55. Science, Technology, andSociety Series, 6.To Catch a Dream. Exploration of Dreaming. David

Koulack. State University of New York Press, Albany,1991. xii, 218 pp. Paper, $14.95. SUNY Series ofDream Studies.The Toxics Directory. References and Resources on

the Health Effects of Toxic Substances. Hanafi Russell,Ed. California Department of Health Services, Berkeley,CA, 1990 (distributor, California Department of Gener-al Services, North Highlands). Variously paged, illus.Paper, $5.15. Publication no. 7540-958-1300-3.The Vertebrate Olfactory System. Chemical

Neuroanatomy, Function and Development. NorbertHalaxz. Akaddmiai Kiad6, Budapest, 1990. xviii, 281pp., illus. $39.Viewing the Earth. The Social Construction of the

Landsat Satellite System. Pamela E. Mack. MIT Press,Cambridge, MA, 1990. xii, 270 pp., illus. $27.50. InsideTechnology.Wetlands. A Threatened Landscape. Michael Wil-

liams, Ed. Blackwell, Cambridge, MA, 1991. x, 419 pp.,illus. $79.95. Institute of British Geographers SpecialPublications Series, 25.

SCIENCE, VOL. 251

UNE CLASSIFIED ADVERTISEMENTS

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POSITIONS OPEN

ASSISTANT PROFESSOR OF BIOLOGY

Full-time; tenure-track position. Ph.D. required;courses may include introductory courses, developmentalbiology, cell biology, genetics, histology, and/or bio-chemsstry. Send curriculum vitae and list of three refer-ences with telephone numbers by 12 April 1991 to:

Dr. Alice SaylerBloomfield College

Bloomfield, NJ 07003Bloomfield is located 15 miles west of Manhattan.

Experience in a multiracial/multicultural teaching envi-ronment preferred. Women and minorities encouraged to

apply. Airmative Action/Equal Opportunity Employer.

ASSISTANT PROFESSORREPRODUCTIVE ENDOCRINOLOGY

Beth Israel Hospital, Boston, invites applications for a

research position in the Division of Reproductive Endo-crinology. Requirements indude a Ph.D. in physiology,2 years of postdoctoral training related to reproductiveendocrinology, experience in molecular biology, and theability to set up own laboratory with development of anindependent research program over a course of 2 years.

Teaching responsibilities at Harvard Medical School are

limited to supervision of basic science research by M.D.fellows. Applicats must demonstrate willingness to de-vote effort to previously planned projects as well as

development ofindividual areas of investigation.Submit curriculum vitae, name, address, and telephone

numbers of three references to: Joseph F. Mortola,Department of Obstetrics and Gynecology, Beth Is-rael Hospital, 330 Brookline Avenue, Boston, MA02215, by 15 May 1991. Beth Israel Hospital is an

Affirmative Action/Equal Opportunity Employer.

MASSACHUSETTS INSTITUTEOF TECHNOLOGY (MrI)

DEPARTMENT OF BIOLOGYCandidates are sought for two tenure-track faculty

positions at the level of ASSISTANT PROFESSOR.Candidates should have significant research experience in

neurobiology, plant biology, or developmental biology.Approaches should stress genetics, molecular biology,cell biology, or/and biochemistry. The responsibilities ofthis position include conduct of an active research pro-

gram and participation in the teaching program of the

department.Applicants should send curriculum vitae and a summa-

ryof proposed research, and arrange to have letters sentfrom three scientists who can provide an evaluation ofthe candidate's accomplishments and future potential forboth research and teaching. Applications and lettersshould be sent to:

Chairman, Biology Search Committeec/o Room 56-511, Department of BiologyMassachusetts Institute of Technology

77 Massachusetts AvenueCambridge, MA 02139

MIT is an Equal Opportunity/Afflrmative Action Employer.

UNIVERSITY OF UTAH

The Department of Obstetrics and Gynecology andthe Program in Human Molecular Biology and Geneticsinvites applications for an

ASSISTANT PROFESSORSHIPREPRODUCTIVE IMMUNOLOGY

The search is limited to individuals with a researchinterest in immunological areas relevant to reproduction.Applicants should have a Ph.D. degree and sufficientadvanced research training to be able to initiate an

independent research program. Interested individualsshould send curriculum vitae, the names of three refer-ences, and a statement of research interests to:

Stephen M. Prescott, M.D.Director

Program in Human Molecular Biology and GeneticsBuilding 500

University of UtahSalt Lake City, UT 84112

or

James R. Scott, M.D.Chairman, Department ofObstetrics and Gynecology

University of Utah Medical CenterSalt Lake City, UT 84132

The University ofUtah is an Equal Opportunity Employ-er and encourages applications from members of minoritygroups and from women.

29 ALkRCH 1991

POSITIONS OPEN

ASSISTANT PROFESSOR: MICROBIOLOGY(tenure track); first-year courses, microbiology, histolo-gy student research, advising. Two tracks to B.S.: fieldbiology and molecular biology. Commitment to teachingundergraduates in church-related liberal arts college;engage in scholarly activities/professional services. Letter,curriculum vitae, copies of undergraduate/graduate tran-

scripts by 12 April 1991 to: Dr. Leonard Schuize,Academic Dean, Texas Lutheran College, Seguin, TX78155. Affirmative Action/Equal Opportunity Employer.

CELL/MOLECULAR BIOLOGISTThe University of Nevada, Reno (UNR), invites ap-

plications for a tenure-track position at the level ofASSISTANT PROFESSOR. This is a 12-month ap-

pointment in both the Departments of Biology (75%)and Biochemistry (25%). Candidates should have at least2 years of postdoctoral experience and the potential to dosignificant research. The successful applicant will occupy

newly renovated and equipped laboratory space and isexpected to develop an externally funded research pro-

gram. Teaching at the undergraduate and graduate levelis expected.

Applicants should submit curriculum vitae, a descrip-tion of research and teaching interests, reprints, and thenames, addresses and telephone numbers of three refer-ences to: Dr. Lee A. Weber, Department of Biology,University of Nevada, Reno, NV 89557.To ensure full consideration applicants should have all

materials on file by 1 May 1991. Position will remainopen until filled. Affirmative Action/Equal OpportunityEmployer. UNR employs only U.S. citizens and alienslawfully authorized to work in the United States.

PLANT BIOLOGISTS. The Department of Horti-cultural Sciences at Texas A&M University intends toadd expertise in molecular biology to an outstandingcorps of applied and fundamental plant scientists. Threetenure-track positions, plant molecular genetics, posthar-vest biology, and horticultural products biology, will befilled at the ASSISTANT PROFESSOR level. Individ-uals will organize and conduct research programs target-ed at fundamental questions, teach graduate and ad-vanced undergraduate courses in their areas of expertise,advise graduate students and postdoctoral associates, andestablish and administer aggressive extramural grantsprograms. Cooperative programs with faculty and re-

search scientists within the department, in other depart-ments on campus, and at off campus research centers will

be encouraged. Candidates must have earned Ph.D.degrees in horticulture, plant physiology, genetics, bio-chemistry, molecular biology, food science, or relatedfields as te to the position sought. Applicantsshould send resumes, official transcripts, and request thatthree letters of recommendation be sent to: Dr. R.Daniel Lineberger, Department of Horticultural Sci-ences, Texas A&M University, College Station, TX,

77843-2133. Information concerning the positions

may be obtained by writing to the aove address or

calling 409-845-5250 (FAX: 409-845-0627). Thedeadline for applications is 15 June 1991, or untilsuitable candidates are found. TexasA&M University isan Equal Opportunity/Affirmative Action Employer.

BIOCHEMISTRY ASSISTANT PROFESSORS,The Mount Sinai School of Medicine. Applications areinvited for two tenure-track positions at the assistantprofessor level in the Department of Biochemistry,Mount Sinai School of Medicine. We seek individualswith research interest in the regulation of metabolism,study of membrane proteins, enzymology, or signaltransduction. The successful applicants will be expectedto develop strong independent research programs withextramural funding and to participate in the teaching ofmedical and graduate students. Current research interestsin the department include: structure and function ofinsulin, insulin-receptor action, protein phosphorylationand signaling, Fc receptors and signaling, regulation andmRNA metabolism, biochemical toxicology of alcohol,hepatitis B virus and HIV replication, molecular mech-anism of energy transduction, conformational propertiesof proteins and ligand binding interactions. Start-upfunds and research space are available for the comingacademic year. Applicants should send curriculum vitae,a statement of research interests, and names of threereferences to: Dr. Arthur I. Cederbaum, Search Com-mittee, Department of Biochemistry, Box 1020, TheMount Sinai School of Medicine, One Gustave L.Levy Place, New York, NY 10029-6574. An EqualOpportunity Employer.

PERSONNEL PLACEMENT 1625

POSITIONS OPEN

ASSISTANT PROFESSOR OF BIOCHEMIS-TRY. Beginning September 1991 to participate in un-dergraduate and graduate teaching and to initiate ahigh-quality research program. Research experience andinterests may be in any field of biochemistry or molecularbiology. This appointment is for 1 year with possiblerenewal for up to 4 years at which point it may beconverted to a tenure-track position. Qualifications:Ph.D. and postdoctoral experience. Send resume (nonci-tizens must include current visa status), statement of re-search interests, and the names of three references by 15June 1991 to: Donald M. Green, Department ofBiochemistry, University ofNew Hampshire (UNH),Durham, NH 03824. UNH is an Affirmative Action/Equal Opportunity Employer.

BIOLOGY, TENURE-TRACK ASSISTANTPROFESSOR. At Augusta College, a 5200-student,senior unit of the University System of Georgia. Acommitment to teaching undergraduates and pursuingscholarly activities, including the direction of studentresearch, is essential. Teaching responsibilities will in-clude introductory biology and invertebrate zoology;preferably marine biology and ichthyology. Ph.D. re-quired. Employment begins 1 September 1991. Sendletter of application, curriculum vitae, and names ofthreereferences with addresses and telephone numbers to: Dr.Russell E. Stullken, Department of Biology, AugustaCollege, Augusta, GA 90910. Applications received by26 April 1991 will be assured of full consideration.Augusta College is an A4ilrmativeAction/Equal OpportunityEmployer and specifically invites and encourages applicationsfrom women and minorities.

Eastern Kentucky University. ASSISTANT PRO-FESSOR, ANATOMICAL SCIENCES. The Depart-ment of Biological Sciences at Eastern Kentucky Univer-sity seeks applicants for a Ph.D-level, tenure-trackposition in anatomy and physiology begining August1991. Teaching responsibilities will involve undergradu-ate courses in human anatomy, advanced human anato-my, and neuroanatomy for allied health students as wellas upper division and graduate-level courses in our M.S.program. The successful candidate will be expected todirect undergraduate and graduate research in an area ofspecialty. Send or FAX letter of application, curriculumvitae, transcripts, description of teaching and researchgoals, and three letters of reference by 25 April 1991 to:Dr. William W. Farrar, Department of BiologicalSciences, Eastern Kentucky University, Richmond,KY 40475. FAX: 606-622-1020. Eastern KentuckyUniversity is an Equal Opportunity/Affirmative Action Em-ployer. Employment eligibility verification required, Immi-gration Reform and Control Act of 1986.

RESEARCH ASSISTANT PROFESSORSTwo research assistant professors are needed to partic-

ipate in team research in the development and applicationof digital imaging microscopy to clinical diagnostics.Ph.D. with background in computer science and biology,biophysics and mathematics is required. Practical experi-ence in computer hardware and software development(UNIX, Forth, FORTRAN, C, Pascal, J language),mathematical modeling, digital image processing tech-niques and solid foundation in the current state-of-the-art of diagnostic markers for cervical and breast carcino-ma is also required. Salary commensurate with ex-perience. Send curriculum vitae and names, addresses,and telephone numbers of three references to: Dr.Charles R. Hackenbrock, Department ofCell Biologyand Anatomy, University ofNorth Carolina at Chap-el Hill, CB# 7090,108 Taylor Hail, Chapel Hill, NC27599-7090 by 15 May 1991. An Equal Opportunity!Affirmative Action Employer. Women and minorities areencouraged to apply.

MOLECULAR BIOLOGIST/BIOCHEMISTA faculty research position at the ASSISTANT/AS-

SOCIATE PROFESSOR level is available starting 1August 1991 for a basic scientist in the urologic oncol-ogy laboratory in the Division of Urology, University ofKentucky Medical Center (UKMC). Candidates musthave a Ph.D. with postdoctoral experience and will beexpected to establish and maintain an extramurally fund-ed research laboratory. Experience in urologic tumors isdesirable but not mandatory. A generous start-up pack-age is available. Send curriculum vitae and references to:Dr. Bruce Lucas, MS-269 UKMC, 800 Rose Street,Lexington, KY 40536. The University ofKentucky is anEqual Opportunity/Affirmative Action Employer.

1626

POSITIONS OPEN

ASSISTANTOR ASSOCIATE PROFESSOR OFCLINICAL NUTRITION. Full-time, tenure-track po-sition. M.D. and/or Ph.D. with clinical nutrition empha-sis is required. Demonstrated research ability and grad-uate teaching competency. Salary commensurate withexperience. Exciting multidisciplinary opportunitiesavailable. Send letter of application, resume, transcripts,and three letters of reference to: Dr. Geza Bruckner,Chair, Department of Clinical Sciences, 229 MedicalCenter Annex Two, University of Kentucky, Lexing-ton, KY 40536-0080.

ASSISTANT/ASSOCIATE PROFESSORLABORATORY OF TOXICOLOGY

HARVARD UNIVERSITYSCHOOL OF PUBLIC HEALTH

The Laboratory ofToxicology is searching for a juniorfaculty member who plans to establish an independent,competitive research program in the broad area of mo-lecular and cellular mechanisms of toxicity. The success-ful applicant's interests will complement the faculty'scurrent strengths, which include mutagenesis and DNArepair, cellular responses to oxidative stress, receptor-mediated toxicity, molecular biology of kidney disease,and control of the mammalian cc cycle. The positionalso includes the opportunity and responsibility for grad-uate and postdoctoral training and teaching. To apply,send curriculum vitae, a short statement of researchinterests, and the names of three references to: ProfessorBruce Demple, Chair, Search Committee, LaboratoryofToxicology, Harvard School of Public Health, 665Huntington Avenue, Boston, MA 02115. HarvardUniversity is committed to increasing the representation ofwomen and minority members among itsfaculty and particu-larly encourages applicationsfrom such candidates.

CARDIOVASCULAR PHYSIOLOGISTThe Department of Veterinary Physiology and Phar-

macology, Texas A&M University, invites applicationsfor a tenure-track faculty position at the level ofASSIST-ANT/ASSOCIATE PROFESSOR. Qualifications in-clude a Ph.D. degree, indicating advanced training incardiovascular physiology, and proven ability to developand conduct a significant research program in this field.Interest in comparative medicine is desirable. The posi-tion will include graduate instruction, and participationwith other medical institutions in cooperative researchprograms. The faculty member will also participate in aspecial program in which candidates are seeking certifi-cation in clinical specialties in addition to the Ph.D.degree. This position offers an opportunity for careerenhancement through the development of successfulresearch and teaching programs, as well as a uniqueprospect for the conduct of cooperative research withassociated medical institutions. Applicants should submitcurriculum vitae and names and addresses of three refer-ences to: Dr. D. R. Clark, Department of VeterinaryPhysiology and Pharmacology, College of VeterinaryMedicine, Texas A&M University, College Station,TX 77843-4466. Applications should be received by 1May 1991.

Texas A&M University is an Equal Opportunity/Affir-mative Action Employer.

ASSISTANT RESEARCHER/PROFESSORPLANT EVOLUTION/SYSTEMATICS

A tenure-track position with split appointment in theHawaiian Evolutionary Biology Program and the De-partment of Botany is available in fall of 1991. Candi-dates must have Ph.D. with research capability in plantevolution/systematics using molecular approaches onHawaiian plants. A multidisciplinary approach to inves-tigating the dynamics ofevolutionary processes would bemost congruent with research goals of the program.Candidates are also expected to teach appropriate courses(one or two per year) in the botany curriculum and assistin the development of the new graduate program inecology, evolution, and conservation biology. Submitcurriculum vitae and names and addresses of three refer-ences to: Dr. Kenneth Y. Kaneshiro, Chair, EECBProgram, University of Hawaii, 3050 Maile Way,Honolulu, HI 96822. Closing date: 30 April 1991.

I More than 150,000 people paid to see your adin SCIENCE. Classified Advertising Depart-ment telephone: 202-326-6555. FAX: 202-682-0816.I

POSITIONS OPEN

TEXAS A&M UNIVERSITYCOLLEGE OF AGRICULTURE

AND LIFE SCIENCESDEPARTMENT OF WILDLIFEAND FISHERIES SCIENCES

Applications are invited for two tenure-track facultypositions in (i) AQUATIC SYSTEMS ECOLOGY,LIMNOLOGY, or ECOTOXICOLOGY, and (ii)WILDLIFE orFISHERIES POPULATION ECOL-OGY as an ASSISTANT, or ASSOCIATE PROFES-SOR beginning in the fall of 1991. Applicants must havea Ph.D., postdoctoral or other experience, a solid publi-cation and grants record, appropriate teaching experi-ence, strong commitment to a growing graduate pro-gram in these areas, and a willingness to participate ininternational research and student training projects em-phasizing Mexico and Latin America. Interested individ-uals should provide a letter of application, curriculumvitae, copies of appropriate publications, statement ofresearch and teaching interests, and the names of at leastthree references. Applications must be received by 15May 1991. Send applications to: Dr. DavidJ. Schmidly,Professor and Head, Wildlife and Fisheries Sciences,Texas A&M University, College Station, TX 77843-2258. Texas A&M is an Equal Opportunity/AffirmativeAction Employer and welcomes applications from qualifiedwomen and minority candidates.

LABORATORY ANIMAL SCIENCE. The Amer-ican Association for Laboratory Animal Science(AALAS) seeks a distinguished professional to serve asEDITOR of the association's journal, LaboratoryAnimalScience. Applicants must be currently active in the field.Additional qualifications include: a significant record ofpublished research in the field of laboratory animalscience and comparative medicine; organizational andteamwork skills; tact and judgment. Editorial experiencedesirable, but not necessary. Submit resumes by 1 June1991 to: Chairman, LAS Editorial Board, AALAS, 70Timber Creek Drive Suite #5, Cordova, TN 38018.

VERTEBRATE PALEONTOLOGIST/CURATORCarnegie Museum ofNatural History seeks applicants

for a curatorial position in vertebrate paleontology tojoin a staff that includes four other curators. Qualfica-tions: Ph.D. with specialization in vertebrate paleontol-ogy; field/research program to complement Carnegie'scollections; experience in curation; ability to obtainresearch funding; willingness to participate in education/exhibit programs. Rank and salary commensurate withexperience. Latest starting date 1 January 1992. Sendcurriculum vitae, up to five recent publications, statementof research program, and names/addresses of five refereesby 15 May 1991 to: Search Committee, VertebratePaleontology, Carnegie Museum of Natural History,4400 Forbes Avenue, Pittsburgh, PA 15213. EqualOpportunity/Affirmative Action Employer.

CHIEF, DIVISION OF DIGESTIVE DISEASESAND NUTRITION. The Department of Medicine ofthe University of North Carolina at Chapel Hill hasopened a search for a chief of the Division of DigestiveDiseases and Nutrition. We seek candidates with strongclinical credentials and a record of productivity in basicor clinical investigation who are capable ofleading a largeand diverse division with vigor and distinction. Interest-ed individuals should reply with their curriculum vitaeand the names of three references to: GI Search Com-mittee, CB# 7030, 547 Burnett-Womack, The Uni-versity of North Carolina-Chapel Hill, Chapel Hill,NC 27599-7030. UNC-Chapel Hill is an Equal Oppor-tunity/Affirmative Action Employer andfemale and minorityapplicants are encouraged to identify themselves.

ENVIRONMENTAL SCIENTIST/BRANCHCHIEF. Permanent full-time position at U.S. Environ-mental Protection Agency's (EPA) Robert S. Kerr Envi-ronmental Research Laboratory, Ada, Oklahoma. Musthave extensive research experience and a strong back-ground in either chemistry, biochemistry, soil microbi-ology, or microbial ecology. Must be able to work withpeople and have demonstrated written and oral commu-nication skills. Salary range: GS-13, $44,348 to$57,650; GS-14, $52,406 to $68,129. Must be U.S.citizen. For a copy of official agency announcement andnecessary forms, write to: Ms. Carolyn Taylor, P.O.Box 1198, Ada, OK 74820 no later than 6 May 1991,or call: 405-332-8800, ext. 228. EPA is an EqualOpportunity Employer.

SCIENCE, VOL. 251

m

Nu~

The University of SydneyAUSTRALIA

CHAIR OFANIMALSCIENCEReference No. 05/04

Applications or expressions of interest are invited for the Chairof Animal Science which will become vacant at the end of1991 following the retirement of Professor E. F. Annison.Current interests of the department include nutrition,reproductive biology and genetics. There is a second Chair ofAnimal Science which is occupied by Professor D. R. Fraserwhose interest is in animal biochemistry. The Department ofAnimal Science is located at two centres. Sydney andCamden. The successful applicant will be based at Camden.It is anticipated that interviews for the Chair will be held threemonths after the closing date.Salary will be at the rate of $A67,812 p.a.The University reserves the right to appoint by invitation andnot to proceed with any appointment for financial or otherreasons.Intending applicants for chair positions should obtain adetailed statement of information concerning the chair fromThe Registrar, address below.Applications (in triplicate for chairs) quoting Reference No.,and including curriculum vitae, list of publications and thenames, addresses and fax. nos., of three referees (oniV threereferees will be contacted in the first instance and if morereferees are nominated they should be ranked in order ofpreference) to the Registrar, Staff Office, University of SydneyNSW 2006 Australia (Fax 6126922058) by 25 Apnl, 1991.

Equal employment opportunity d no smokingin the workplace ae University policy.

m -L a

UNIVERSITY OF HONG KONGReader/Senior Lecturer in Anatomy

(Ref. 90/91-68)Applications are invited for a Readership/Senior Lectureship in the Depart-ment of Anatomy, tenable from September 1, 1991. The appointment willbe full time on either superannuable terms, or a two-year fixed termcontract. Appointments on secondment would also be considered.Applicants should be experienced teachers of gross anatomy. The appoin-tee will be expected to play a major role in the co-ordination anddevelopment of the Department's teaching programmes in gross anatomy,principally for preclinical medical students. Applicants should preferablyhold a medical qualification but this should not discourage other experi-enced teachers of gross anatomy from applying.

Preference will be given to candidates who have a strong researchcommitment in one of the Department's existing areas of expertise whichinclude Cancer Biology, Cell Biology, Neurobiology, Neuroendocrinology,Oral Biology and Reproductive Biology.

Annual salaries [superannuable for permanent staff and non-superannuablebut attracting 25% (taxable) terminal gratuity for contract staff] are on thescales:

Reader HK$453,780-602,880 (9 points)Senior Lecturer HK$435,000-584,340 (9 points)(approx. US$1 =HK$7.80 as of February 12, 1991).

Starting salary will depend on qualifications and experience. At currentrates, salaries tax will not exceed 15% of gross income. Housing at acharge of 7.5% of salary, children's education allowances, leave, andmedical benefits are provided.

Further particulars and application forms may be obtained from Appoint-ments (39095), Association of Commonwealth Universities, 36 GordonSquare, London WC1 H OPF, UK; or from the Appointments Unit, Registry,University of Hong Kong, Hong Kong (Fax (852)-5592058; E-mail APPTUN-IT@HKUVM1 .HKU.HK).

Closes 3 May 1991.

FACULTY POSITIONS IN BIOCHEMISTRYand

CELL BIOLOGYSt. Jude Children's Research Hospital

St. Jude Children's Research Hospital, a private research institute, isengaged in a major expansion of its facilities and scientific activities. A newresearch building to be completed in early 1991 will provide 240,000square feet of new laboratory space which will house the institute's basicscience programs. As part of this expansion, new faculty positions are nowavailable in the Departments of Biochemistry and Cell Biology. Althoughpreference will be given to applicants who have recently completedpostdoctoral training and are seeking positions at the level of AssistantMember, more senior investigators with appropriate research interests andqualifications will be considered for positions of higher faculty rank.Candidates with programs focusing on the regulation of cell growth,differentiation and transformation, the biochemistry and molecular biologyof signal transduction, and mechanisms of gene regulation are particularlyencouraged to apply. Opportunities exist for collaborative interactions withongoing basic research programs in Virology and Molecular Biology,Immunology, and Pharmacology, as well as with clinical investigators inHematology/Oncology and Infectious Diseases. In addition to new facilitiesand excellent start-up funds, salaries are nationally competitive and includea generous benefits package. A strong institutional commitment to itsfaculty ensures stability in program development and continuity of researchactivities.Applicants should submit a curriculum vitae, a letter summarizing theirresearch accomplishments and goals, and the names of three references toeither: Dr. James N. Ihle

orDr. Charles Sherr

St. Jude Children's Research Hospital332 N. Lauderdale

Memphis, TN 38105 USASJCRH IS AN AFFIRMATIVE ACTION/EQUAL OPPORTUNITY EMPLOYER

DEPARTMENT OF HEALTH AND HUMAN SERVICESPUBLIC HEALTH SERVICE

FOOD AND DRUG ADMINISTRATIONCENTER FOR FOOD SAFETY AND APPLIED NUTRITION

DIRECTOR. OFFICE OF SEAFOOD

The Food and Drug Administration invites applications for the positionof Director of the new Office of Seafood in the Center for. Food Safetyand Applied Nutrition. The Director will provide marine sciencesexpertise to expand and direct the Center's seafood safety research andregulatory programs. Research Is conducted on seafood, aquacultureand seafood harvesting and processing, as they are affected by chemical.blotoxic or microbial contamination. Regulatory programs to ensurethat all seafood products are safe and properly labelled are theresponsibility of this office. Strong leadership is necessary for thefederal programs, federal/state programs, and others such as theNational Shellfish Sanitation Program.

QUALIFICATIONS: Experience is required in the biological or chemicalsciences, with emphasis on food sciences, food engineering/technology,marine biology, ichthyology, parasitology, food microbiology, etc., asrelated to seafood safety. Candidates must be nationally andinternationally recognized by the scientific community, must meet U.S.OPM qualifications requirements and must be U.S. citizens. A Ph.D.is preferred but consideration will be given to all applicants withMaster's or Bachelor's degrees and appropriate experience.

SALARY: Appointment will be to a full-time. permanent position witha salary range of $61,643 to $80,138 per year dependent onqualifications. This position is projected for Inclusion in the SeniorExecutive Service which has a salary range of $87,000 to $108,300.

LOCATION: The Office of Seafood will be located in the Washington,DC Metropolitan Area, with research and technical support facilities inDauphin Island, AL and Daville, RI.

TO APPLY: Candidates should send a current CV or Application forFederal Employment and bibliography to Dr. Dougls L. Archer,Deputy Director, Center for Food Safety and Applied Nutrition(HFF-2), 200 C Street, S.W., Wahito D.C. 20204. Applicationsfor this position must be postmarked not later than April 20, 1991.

The Food and Drug Administration is Smoke FreeThe Food and Drug Adnministration is an Equal Opportunity Employer

ENDOWED PROFESSORSHIPTEXAS A&M UNIVERSITY

The Department of Biochemistry and Biophysics isseeking applications for the Wolfe-Welch Professorshipin Chemistry. Applicants should have a Ph.D. and arecord ofsignificant research accomplishments supportedby competitive funding. Outstanding candidates in allresearch areas will be considered.

Applicants should send curriculum vitae, list of publi-cations, a brief description of current and future researchdirections, and have three letters of reference sent to: Dr.Robert D. Wells, Department of Biochemistry andBiophysics, Texas A&M University, College Station,TX 77843-2128.The Texas A&M University System is an Affirmative

Action/Equal Opportunity Employer.PROFESSOR AND HEAD. Department of Oral

Biology, University of Illinois at Chicago (UIC), Collegeof Dentistry.Nominations and applications are now being accepted

for the position of head, Department of Ora Biology,the University of Illinois at Chicago, College of Dentis-try. This position affords an exciting opportunity to builda broadly based department with the mandate to designprograms of academic excellence in the disciplines thatrelate to oral biology. The department will be a core basicscience department in the College of Dentistry and willalso develop collaborations and interactions throughoutthe UIC community. Interests of current faculty includebiology and pathology of the jaw joint and oral-facialdevelopment, mineralization, connective tissue biology,and neurophysiology. The department participates inundergraduate, graduate, and postgraduate teaching pro-grams and faculty are expected to perform meritoriousresearch. Teaching responsibilities include gross andneuro anatomy, oral and general histology, and dentalanatomy with the expectation of expansion into otherareas.

Qualifications for the headship include an earneddoctoral degree (Ph.D. and/or D.D.S., D.M.D., M.D.).Evidence of the ability to develop and administer anindependent research program and demonstrated leader-ship potential is essential. Salary is competitive anddependent upon the qualifications and experience of thecandidate. The position is available immediately.The University ofIllinois is an Affirmative Action/Equal

Opportunity Employer. For full consideration, send nom-inations and applications along with the curriculum vitaeand the names of three professional references by 31 May1991 to: Dr. R. John Solaro, Chair, Search Commit-tee for the Oral Biology Department Headship, UICCollege of Dentistry, Office of the Dean (M/C 621),Box 6998, Chicago, IL 60680.

CHAIR, DIVISION OF MEDICINAL CHEM-ISTRY AND NATURAL PRODUCTS. The Schoolof Pharmacy at the University of North Carolina atChapel Hill invites application for the position of chairand professor of the Division of Medicinal Chemistryand Natural Products. The division chair is responsiblefor providing leadership to the research and teachingprograms of the division. Candidates must have a Ph.D.in medicinal chemistry or an area related to the researchand teaching of the division, demonstrated success indeveloping external funding, good leadership qualities,and a commitment to scholarly achievement. The posi-tion will be available 1 January 1992 and will remainopen until a suitable candidate is appointed. Interestedapplicants should contact: Dr. George H. Cocolas,School of Pharmacy, University of North Carolina,CB# 7360 Beard Hall, Chapel Hill, NC 27599. AnEqual Opportunity/Affirnative Action Employer.

1628

POSITIONS OPEN

LEADERFOR THE SURFACE WATERAND MODELING TEAM

ENVIRONMENTAL PROCESSESAND EFFECTS RESEARCH

OFFICE OF RESEARCH AND DEVELOPMENTWASHINGTON, D.C.$61,643 to $80,138

U.S. Environmental Protection Agency (EPA) is seek-ing highly qualified candidates for the position of leaderfor the Surface Water and Modeling Team, Office ofEnvironmental Processes and Effects Research(OEPER). OEPER, which is in the Office of Researchand Development (ORD), is responsible for the devel-opment of scientific methods and data necessary tounderstand, predict, and manage the entry, movement,and fate of pollutants and their effects on the food chain,as well as their effects on nonhuman organisms andecosystems. This research is conducted in ORD's fieldresearch laboratories. The team leader is responsible forthe planning, coordination, and review of a comprehen-sive research program on global climate change, strato-spheric ozone depletion, Arctic environmental protec-tion, and ecological impacts due to air pollution. Theteam leader, located in Washington, D.C., supervises aninterdisciplinary technical staff of four. Applicant musthave a Ph.D. in systems ecology or equivalent experience.Mandatory technical qualifications:(i) Demonstrated ability to plan/develop complex re-

search programs relevant to the needs of EPA.(ii) Demonstrated ability to manage/implement com-

plex research programs relevant to the needs of EPA.To meet the requirements of the position, applicant

must submit a completed SF-171 (application for federalemployment) to: Ms. Barbara Ashton, PM-212, Head-quarter's Client Service Division, Environmental Pro-tection Agency, 401 M Street, S.W., Washington,D.C. 20460. Telephone: 202-382-2973. The vacancyannouncement number is: 1ORD-687. Resumes with-out accompanying SF-171s will not be considered. Ap-plications must be received by 19 April 1991. EPA is anEqual Opportunity Employer.

ENDOWED CHAIR INBIOLOGICAL CONTROL

The Department of Entomology and Nematology,IFAS, University of Florida, invites applications andnominations for the newly established Davies, Fischerand Eckes Chair in Biological Control. The eminentscholar will develop innovative research programs onbiological control of arthropods, nematodes, and orweeds. His/her research may be fundamental or applied,and may focus on model systems, beneficial organisms,pest complexes, or other biological processes. It is antic-ipated that the research results generated by this positionwill benefit the citrus industry. The incumbent willinteract with biocontrol faculty statewide, and develop astrong graduate program, including instruction. Candi-dates are expected to be internationally recognized schol-ars, possess a doctorate, have a proven record of obtain-ing extramural financial support, and display a strongcommitment to graduate education. Applicants mustsubmit, by 1 June 1991 curriculum vitae, statement 6fresearch interests, and names of five references sp: JohnL. Capinera, Chairman, Department of Entomologyand Nematology, Building 970, Hull Road, Univer-sity of Florida, Gainesville, FL 32611-0740. TheUniversity of Florida is an Equal Opportunity/AffirmativeAction Employer.

POSITIONS OPEN

CHAIRPERSONDEPARTMENT OF BIOCHEMISTRYAND MOLECULAR BIOLOGY

LOUISIANA STATE UNIVERSITYMEDICAL CENTER, SHREVEPORT

Applications and nominations are invited for the po-

sition ofPROFESSOR AND HEAD (chairperson) ofthe Department of Biochemistry and Molecular Biologyat Louisiana State University Medical Center (LSUMC),Shreveport. The department currently consists of ninefaculty, eight fellows, and 23 doctoral students and isresponsible for teaching freshman medical students,maintaining state-of-the-art research programs in molec-ular biology, and training doctoral students. The depart-ment is well equipped, well funded, and will expand nowand with the opening of the ten-story Biomedical Re-search Institute which will focus on research in molecularbiology, cardiovascular sciences, and neurobiology. Weseek candidates with an outstanding record of researchachievement, proven leadership skills, and a commitmentto training medical and doctoral students. Candidatesshould have a Ph.D. and/or M.D. and a record ofscientific excellence as evidenced by publications andgrant awards. Candidates should submit curriculum vi-tae, a summary of research interests, and at least threeletters of reference to: Dr. Dennis J. O'CallaghanChair of Search Committee, Department of Microbi-ology and Immunology, LSUMC, 1501 Kings High-way, Shreveport, LA 71130.LSUMS is an Equal Opportunity/Affirmative Action

Employer.

DIRECTOR: FIELD RESEARCH CENTERPosition open November 1991 for Director of Kari-

soke Research Center (KRC) for studies of mountaingorilla and African montane ecology in Volcano NationalPark, Rwanda, Africa. Ph.D., first aid, and fluent Frenchrequired. Contract for 1 year.

Also position open January 1992 for assistant todirector. Bachelor's degree, frst aid, and French re-quired.Send resume, letter of application including statement

ofwhy you wish to work at KRC and special skills usefulin conservation and research activities, and three lettersof reference to: The Digit Fund, 45 Inverness DriveEast, Englewood, CO 80112. All materials must bereceived by 1 May 1991.

THE UNIVERSITY OF CALGARYVICE-PRESIDENT (RESEARCH)

The University of Calgary is seeking a Vice-President(Research). The successful candidate will be appointedinitially as Associate Vice-President (Research) effective1 July 1991 (or as soon as possible thereafter), and willassume the office of Vice-President (Research) on 1 July1992.The University of Calgary is a dynamic and innovative

research and teaching university of growing national andinternational stature. Academic programs are offeredthrough 16 faculties in a wide range of undergraduate,graduate, and professional fields. The University of Cal-gary has an enrolment of more than 20,000 students,with 1,800 faculty and 2,300 support staff. The campusincludes 30 buildings on a 122-hectare site. The currentoperating budget is $180 million. The value of fundedresearch exceeds $50 million annually.

Reporting to the President, the Vice-President (Re-search) is responsible for advancing and supportinguniversity research and technology transfer. The idealcandidate will have: qualifications appropriate to the rankof full professor, a demonstrated record of leadership inresearch within a university or like institution, senioradministrative experience, superior organizational andplanning abilities, excellent communications skills andthe ability to work effectively within an academic envi-ronment, and with senior people in government andindustry.

In accordance with Canadian immigration requirements,priority will be given to Canadian citizens and permanentresidents of Canada. The University of Calgary has anEmployment Equity Program and encourages applicationsfrom all qualified candidates, including women, aboriginalpeople, visible minorities, and people with disabilities.

This position represents an important leadership op-portunity at one of Canada's finest universities. Applica-tions or nominations should be directed, in confidence,not later than 30 April 1991, to: Murray Fraser,President, The University of Calgary, 2500 Univer-sity Drive N.W., Calgary, Alberta T2N 1N4 Canada.

SCIENCE, VOL. 251

POSITIONS OPENp

UNIVERSITY OF CAMBRIDGEPROFESSORSHIPOF VIROLOGY

Aplications are invited for this newly estab-lished professorship.

Pensionable stipend: £32,663 a year.Further information from: The Secretary

General of the Faculties, General Board Of-fice, The Old Schools, Cambridge CB2 TIT,England, to whom applications (ten copies),marked "confidential,' should be sent with thenames of two referees by 29 April 1991.The university follows an Equal Opportunities

policy.

BONUS CIRCULATIONFOR YOUR CLASSIFIED AD

AT ASM MEETINGOur issue of 26 April 1991 will be distributed

to scientists attending the 1991 ASM Meeting inDallas, Texas.

Deadline for submission of line classified ads:11 April 1991

SCIENCEClassified Advertising

Telephone: 202-326-6955FAX: 202-682-0816

NIH SEEKS ASECTION CHIEFNational Institute of Allergy and

Infectious DiseasesThe Genetics and Transplantation Branch of the Divisionof Allergy, Immunology and Transplantation is seekingan outstanding Physician (M.D.) or Scientist (Ph.D.) withspecific skills in the area of Clinical Transplantation andTransplantation Immunobiology. Candidate should bebroadly qualified and should have research experience.

If applicant is a physician, a Transplant Surgeon orPhysician with appropriate speciality training ispreferred.

Responsibilities will include planning and conducting anextramural scientific research and clinical trial programand will permit the opportunity to maintain an academicaffiliation. We offer a competitive salary and outstandingbenefits. Physician's comparability pay up to $20,000may be applicable. Please contact:

Dr. Robert A. GoldsteinNIAID/National Institutes of HealthBuilding 31, Room 7A529000 Rockville PikeBethesda, MD 20892Phone: (301) 496-1886

U.S. Citizenship is RequiredNIH is an Equal Opportunity Employer

lqopgl

qA HEP-'

With over $500 million dedicated to R&D last year alone,Abbott has stood firm in its belief that the greatest advances comefrom an extensive corporate commitment to the research and devel-opment of innovative technologies. The result: with Abbott you willfind greater challenges and resources to further your career.

ASSISTANT BIOLOGISTIn order to complete R&D projects, the selected candidate will

perform technical tasks such as biochemical and inununoassays, andassist in developing new biotest methodology. This individual willalso use various biochemicalfnlmnunochemical techniques to purifybiological substances, and assist with characterization of the sub-stance.

We require a BS or MS degree in Biology, Biochemistry orImmunology (Microbiology). Some R&D experience including cel-lular inununology and cell culture preferred.

Abbott offers an excellent salary and benefits package includ-ing profit sharing and a stock retirement plan. We are located in asuburban setting approximately 30 miles north of Chicago. For con-sideration, please send your resume to: Ann Ribbens, CorporatePlacement, Job #14448, Abbott Laboratories, One Abbott ParkRd., Abbott Park, IL 60064. Abbott is an Affirmative ActionEmployer.

ABBOTF LABORATORIESB * Heafth Car

Worldwidelows-1oo1

A J

ELECTRON& LIGHT

MICROSCOPISTB.S./M.S.

Merck, the world leader in medical re-search, is offering an excellent careeropportunity for an experienced electronand light microscopist to join our De-partment of Bone Biology. The selectedcandidate will manage the departmentalmicroscopy facility containing extensiveTEM/LM, microtomy confocal, imageprocessing and fluorescence capabilities.Requirements for this position include aB.S.IM.S. in biology or the equivalent, aminimum of 5 years experience in TEM,LM, and general photography/darkroomtechnique, and familiarity with immu-nocytochemical techniques.Excellent salary and benefits accom-pany this position at our modern re-search facility located 25 miles north-west of Philadelphia. Please sendresume and salary requirements to:Personnel Manager A-7, ResearchPersonnel WP42-2, Merck Sharp &Dohme Research Laboratories, WestPoint, PA 19486. An equal opportunity/affirmative action employer.

We'll Help You BuildA New Lab

PR\9\

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Let the free Science product in-formation service put you in touchwith the vendors whose productsyou will need.

Simply write us a letter statingthe specifics about your proposedlab and the instruments andsupplies you need. We will do therest. Write to:

SCIENCE MagazineNew Lab Service Department1515 BroadwayNew York, NY 10036

~ The ~ Wekly of Reseatch

SC1ENCE

The CARDEZA FOUNDATION FORHEMATOLOGIC RESEARCH, JEF-FERSON MEDICAL COLLEGE, isseeking applicants for positions at thepost-doctoral and Assistant Professorlevels for basic studies of endothelialcell structure and function as related tohemostasis and thrombosis. Areas ofresearch include endothelial mem-brane glycoprotein synthesis, structureand function; platelet interactions withendothelial cells; and endothelial-ma-trix interactions. Candidates shouldhave a working knowledge of tissueculture, membrane and protein bio-chemical techniques, hybridoma tech-nology and basic techniques of molec-ular biology. Post-doctoral appoint-ments are for 2-3 years andappointments at Assistant Professorlevel are for 3-5 years, both renew-able. Interested applicants should sub-mit curriculum vitae, a summary state-ment of their interests and names ofthree references to Dr. S. Shapiro, Di-rector, Cardeza Foundation for Hema-tologic Research, Jefferson MedicalCollege, 1015 Walnut Street, Philadel-phia, PA 19107.An Affirmative Action/Equal Opportunity Employer.

k

5

9

POSITIONS OPEN

DEAN, University of South Florida (USF) College ofMedicine. The University of South Florida College ofMedicine is seeking applicants for the position of dean.The dean is responsible for the education, research, andclinical programs conducted at the University of SouthFlorida College of Medicine. The college is one of threein the state of Florida. USF opened in 1960 and theCollege of Medicine began in 1971. USF is the 35thlargest university in the nation with more than 30,000students and is located in an expanding metropolitan areaof more than 2 million people. The Health SciencesCenter also includes a College of Public Health and a

College ofNursing. It has approximately 475 faculty and96 students in each class. Applicants should have an

M.D. degree or equivalent; should have considerableacademic, administrative, and leadership skills; andshould meet standards for appointment at the full pro-

fessor level. Applicants should send their curriculum vitaeand the names of five references to: Allan L. Goldman,M.D., Chairman, Dean Search Committee, Universi-ty of South Florida College of Medicine, Box 19,12901 Bruce B. Downs Boulevard, Tampa, FL33612. USF is an Equal Opportunity/Affirnative ActionEmployer.

ASSISTANT DEANCOORDINATOR OF

INTERNATIONAL PROGRAMSThe College of Agriculture and Life Sciences at North

Carolina State University invites applications and nomi-nations for the position of coordinator of internationalprograms to be available 1 July 1991. Duties indudeproviding leadership and coordinating activities for theinternational programs of the college. Programs will bedirected toward international activities in both developedand developing countries, such as student exchanges andstudy abroad, visiting scholars, and faculty developmentthrough collaborative linkages with overseas institutionsand traditional technical assistance programs. The coor-dinator will report to the dean of the college and willcollaborate and work with associate deans and directorsofresearch, teaching, and extension as well as departmentheads in all international aspects of college programs.A doctorate in agricultural, social, or biological sci-

ences or other closely related field and administrativeexpertise as well as experience and familiarity with inter-national programs and organizations are required.Send a letter of application, curriculum vitae, and

names, addresses, and telephone numbers of three refer-ences: Dr. Johnny C. Wynne, Chairperson of SearchCommittee, Box 7620, North Carohna State Univer-sity, Raleigh, NC 27695-7620. Applications must bereceived by 19 April 1991. North Carolina State Univer-sity is an Equal Opportunity/Affirmative Action Employer.

MOLECULAR GENETICISTPSYCHOPHARMACOLOGIST

Mayo Clinic/Mayo Medical School invites applicantsfor a FACULTY POSITION in the Department ofPsychiatry and Psychology, in close collaboration withmembers in the Department ofPharmacology and/or theDepartment of Biochemistry and Molecular Biology.Candidates should have primary interests in major psy-chiatric disorders and be pursuing these interests with themethods ofmolecular genetics and/or molecular pharma-cology. M.D. and clinical training in psychiatry are

desirable but not required. Mayo will provide generousspace and start-up funds in addition to an attractivepackage of salary and benefits. Academic rank will bedetermined by qualifications; established investigatorsare also encouraged to apply. Submit curriculum vitaewith names and addresses of three or more references to:Toshihiko Maruta, M.D., Chairperson of SearchCommittee, Department of Psychiatry and Psycholo-gy, Mayo Medical School, Rochester, MN 55905. AnEqual Opportunity/Affirmative Action Employer.

POSITIONS OPEN

TRANSPLANTATION IMMUNOLOGISTDIRECTOR OF RESEARCH

We are seeking a Ph.D. immunologist with postdoc-toral experience in transplantation biology to directresearch activities in the Section ofTransplantation in theDepartment of Surgery with a joint appointment in theDepartment of Microbiology. This individual wouldcollaborate with surgeons in the Section of Transplanta-tion and members of the Department of Microbiologyand Immunology. This is a full-time academic position atthe rank of ASSISTANT PROFESSOR or as is com-mensurate with qualifications. Send curriculum vitae andthree professional references to:

Stephen T. Bartlett, M.D.Associate Professor and Chief

Section of Transplantation SurgeryDivision of General Surgery

University of Maryland Hospitalcdo Lois Reisig

405 West Redwood Street, 5th FloorBaltimore, MD 21201

Equal Opportunity Employer, M/F/H/V.Minorities andjfemales are encouraged to apply.

MANAGERTECHNICAL INFORMATION SERVICESThe Coca-Cola Company is seeking a manager, Tech-

nical Information Services, to manage the resources

library for its technical division. Responsibilities includesupervising the acquisition, cataloging and circulation ofbooks, periodicals and other published materials; man-

aging the automation of library systems; preparing a

quarterly literature awareness bulletin and announce-ments of recent literature searches and Company reports;assisting in literature searching and general referencework; supervising two information scientists and twolibrary assistants; preparing and managing an annualbudget. Qualifications for the position include 5 to 7years in a technical library setting; experience with libraryand special project management; bachelor's degree in anatural or applied science plus a master's degree in libraryscience. The Coca-Cola Company is an Equal OpportunityEmployer.

Resumes, along with salary history, should be sent to:The Coca-Cola Company, Corporate Staffing, De-partment LP, P.O. Drawer 1734, Atlanta, GA 30301.

FACULTY POSITIONS IN NUTRITIONALBIOCHEMISTRY. The Department of Nutrition ofCase Western Reserve University is undergoing majorexpansion at Mount Sinai Medical Center in Cleveland.We seek two investigators working on the regulation ofcarbon flux through the pathways of nutrient metabo-lism, in humans and in animal models. Candidates areexpected to develop independent research programs us-ing modern techniques of stable isotope technology,biochemistry, or molecular biology. They will teach atthe graduate level and train graduate students and post-docs. Submit curriculum vitae, representative reprints,description of research plans, and three letters of refer-ence to: Dr. Henri Brunengraber, Chairman, Depart-ment of Nutrition, Case Western Reserve University,Cleveland, OH 44106. Case Western Reserve Universityis an Equal Opportunity Employer. Women and members ofminority groups are encouraged to apply.

CASTLETON STATE COLLEGE. BIOLOGYFACULTY VACANCY. Castleton State College seeksa fourth biologist for the 1991 to 1992 academic yearand following in what will likely be a tenure-trackappointment. Salary is based on degrees and experienceaccording to a negotiated contract. The primary teachingresponsibility will be to collaborate in teaching humananatomy and physiology. The successful applicant will bea dynamic educator with a Ph.D. in biology (strongABD's considered). The candidate will be able to teachcourses in specialty such as vertebrate biology, physiolo-gy or cell biology. Ability to teach introductory chemis-tr is desirable. The candidate should be able to workeSectively with colleagues and students as well as con-tribute to the vitality and growth of the department. Theposition will begin in fall of 1991. Application materialmust include a resume, statement of teaching and re-search interests, three letters of reference and transcripts.Materials should be sent to the address below. Review ofapplicants will begin on 8 April 1991. Dr. Joseph T.Mark, Academic Dean, Biology Search, WoodruffRoom 3, Castleton State College, Castleton, VT05735. Equal Opportunity Employer.

SCIENCE, VOL. 251

J~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~RESEARCHSCIENTIST

The Department of Anesthesiology at the NassauCounty Medical Center is seeking an individual to:1. Conductaprogram of appropriate independent

investigation;2. Plan and supervisethe expansion of our present

research laboratory facilities;3. Maintain and supervise our vascular smooth

muscle laboratory;4. Assist the Departmental Staff with research

projects;5. Participate in didactic program for residents.A Ph.D. degree, good communication and dataanalysis skills, computer programming knowledge,and publication record are necessary.The Nassau County Medical Center, located on LongIsland, is a 615 bed teaching hospital affiliated withthe State University of New York at Stony Brook.Qualified individuals are eligible for academicappointments at that institution.As public employees of Nassau County, ResearchScientists receive excellent salary, benefits and jobsecurity. Interested candidates should send their CVand the names of three references in confidence to:

KENNETH J. FREESE, M.D.Chairman

Department of Anesthesiology

1 NASSAU COUNTYMEDICAL CENTER2201 Hempstead Tpke.East Meadow, NY 11554

Nassau County is an Equal Opportunity Employer

BONUS CIRCULATIONFOR YOUR CLASSIFIED AD

AT ASM MEETINGOur issue of26 April 1991 will be distributed

to scientists attending the 1991 ASM Meeting inDallas, Texas. Deadline for submission of lineclassified ads: 11 April 1991.

SCIENCE Classified AdvertisingTelephone: 202-326-6555

FAX: 202-682-0816

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MOLECULAR BIOLOGY & GENETICS

Several faculty and staff positions to be filled duringthe next 2-3 tears as part of a major expansion andmodernization of the Department of Biochemistry & Mo-lecular Biology at the Albany Medical College. Currentlyavailable positions include:

* 2 Full Professors* 2 Associate Professors* 3 Assistant Professors* 10 Postdoctoral Fellows & Technicians

The Albany Medical College has made a major com-mitment to the growth and development of molecularbiology and molecular genetics. The newly constitutedDepartment of Biochemistry & Molecular Biology willoccupy state-of-the-art laboratories in a modern researchbuilding. Shared departmental facilities will include anextensive cell-culture complex and major equipment formodern biology. Competitive salaries and start-up fundswill be offered to qualified candidates.

The Albany Medical College (Est. 1839) has a proudhistory of research, teaching, and patient care. The city ofAlbany, state capital of New York, offers an excellentlifestyle with easy access to New York City, Boston, andMontreal. Surrounding rural communities offer evervthingfrom the splendor of the Adirondack mountains to thequiet charm of the Berkshire foothills.

Departmental interests center on the regulation ofgene expression, but exceptional candidates in any area ofmolecular biology or molecular genetics will be seriouslyconsidered. The successful faculty candidates will be expect-ed to establish vigorous independent research programsand attract substantial external funding. Please send cumcu-lum vitae, statement of research interests and goals, and thenames of at least three refarences to:

Professor Kevin J. A Davies, ChairmanDepartment of Biodcemist & Molecular Biology

The Albany Medical CollegeNew Scotand Avenue

Albany, New York 12208An Equal Opposnity/Affiratin Aatim Emplmor.

CHIEF, LABORATORY OF IMMUNOLOGYDIVISION OF BACTERIAL PRODUCTS

CENTER FOR BIOLOGICS EVALUATION AND RESEARCHDHHS/PHS/FOOD AND DRUG ADMINISTRATION

The Food and Drug Administration (FDA), Center for Biologics Evaluation and Research(CBER), Division of Bacterial Products, invites applications for the position of Chief,Laboratory of Immunology, located in Bethesda, Maryland. The Laboratory is responsiblefor the research and regulatory programs related to the immune response to bacterialvaccines and related biologics. This is a supervisory interdisciplinary position appropriatefor a chemist, microbiologist, or biologist with post-graduate training. Physicians may alsoapply for this position; if selected, additional responsibilities would include medicalevaluation of selected clinical studies for the Laboratory and the Division of BacterialProducts, and may include the performance of clinical studies. The Laboratory Chief isresponsible for independently planning, organizing, and conducting research in molecu-lar, cellular and applied immunology for understanding and predicting the immuneresponse to existing and future vaccines for significant bacterial infections. Therefore, anextensive background in immunology and demonstrated experience in directing aresearch laboratory or program is required.

Salary range for chemist, microbiologist, and biologist is $52,406 to $68,129 at the GM-14level and $61,643 to $80,138 at the GM-15 level. Salary range for physician is $61,141 to$76,864 at the GM-14 level and $65,753 to $84,248 at the GM-15 level. Physicians mayalso be eligible for a Physician's Comparability Allowance up to $20,000 per year. Salaryis commensurate with education and experience. The grade of the position depends uponthe research qualifications of the candidate as determined by the CBER Peer ReviewBoard. U.S. citizenship is required.

Application for Federal Employment (SF-1 71) or resume must be received at the followingaddress no later than April 25, 1991:

FDA/Center for Biologics Evaluation and ResearchAttention: Ms. A. J. Wilcox, DBP2NIH Building 29, Room 1048800 Rockville PikeBethesda, MD 20892

FDA IS AN EQUAL OPPORTUNITY EMPLOYER

POSITIONS OPEN

TENURE-TRACK POSITION INGASTROINTESTINAL CELLULAR

BIOCHEMISTRY

Applications are invited for a tenure-track position atthe ASSISTANT/ASSOCIATE/FULL PROFES-SOR level in the Department of Internal MedicineSchool ofMedicine, St. Louis University. We are seekinga person with high promise in research who is interestedin working on the biochemical basis of gastrointestinalcell function. Applicants must have a Ph.D. in biochem-istry or cell biology or an M.D. degree with at least 2years of relevant postdoctoral experience. Submit curric-ulum vitae, a statement of research interests, and threeletters of recommendation to: Jerry D. Gardner, M.D.,Associate Chairman, Department of Internal Medi-cine, St. Louis University School of Medicine, 1402South Grand Boulevard, St. Louis, MO 63104. St.Louiis University is an Affirtmative Action/Equal Opportuni-ty Employer.

CAREER SCIENTIST (TENURE-TRACK FAC-ULTY). Position with primary appointment in the De-partment of Anesthesiology and possible joint appoint-ment in a basic science department. Candidate shouldpossess a Ph.D., M.D., or equivalent degree with post-doctoral experience and demonstrated ability to attractextramural research funding. Primary research interestsshould be in the areas of molecular pharmacology,physiology, or biochemistry with direct or indirect ap-plicability to anesthesiology, critical care medicine, orpain management. Generous laboratory space and start-up funds provided. Academic rank will be determined byqualifications. Established investigators are especially en-couraged to apply. Please send a description of researchinterests, curriculum vitae, and names and telephonenumbers of three references to: P. R. Housmans, M.D.,Ph.D., Mayo Medical School, Rochester, MN 55905by 1 May 1991. Mayo Foundation is an AffirtnativeAction/Equal Opportuntzity Educator and Employer.

FACULTY POSITION:ASSISTANT PROFESSOR

The Department of Obstetrics and Gynecology at TheUniversity of Alabama at Birmingham has a facultyposition open in the Division of Reproductive Biologyand Endocrinology. Applicant should be U.S. citizenwith a Ph.D. in endocrinology, physiology or embryol-ogy obtained from a U.S. university. The applicantshould have 2 to 3 years postdoctoral fellowship inreproductive endocrinology and must have had hands-onexperience in standard and natural cycle 1VR A strongresearch background with an interest in ovarian folliclephysiology is required. The position is at the assistantprofessor level, tenure-earning. The applicant should beavailable to assume clinical IVF duties mid-summer1991.

Please send curriculum vitae and the names of threereferences by 15 May 1991 to: Richard E. Blackwell,Ph.D., M.D., Professor and Division Director, De-partment of Obstetrics and Gynecology, The Univer-sity of Alabama at Birmingham, UAB Station, Bir-mingham, AL 35294. An Equial Opporttutnity/AffirtmzatiteAction Emtployer.

MOLECULAR NEUROBIOLOGYPOSTDOCTORAL POSITIONS

NATIONAL INSTITUTE ON ALCOHOLABUSE AND ALCOHOLISM

The Section on Molecular Neurobiology, NationalInstitute on Alcohol Abuse and Alcoholism (NIAAA)has a position available beginning 1 July 1991 to (i)study the structure and function of GABAA receptorsusing mutagenesis techniques and (ii) investigate themolecular basis of alcohol's effects on GABAA receptorfunction. Approaches to be used include: PCR tech-niques, Xenopus oocyte expression, site-directed muta-genesis, ligand binding, and electrophysiology. Appli-cants must have less than 3 sears previous postdoctoralexperience. Annual salary is $25,000 to $28,000. Appli-cants with expertise and interests in molecular neurobi-ology, Xenopus expression systems, and electrophysiol-ogy are encouraged to apply. Please send curriculumvitae and three letters of reference to: Claire M. Fraser,Ph.D., Chief, Section on Molecular Neurobiology,Laboratory of Physiologic and Pharmacologic Stud-ies, NIAAA, 12501 Washington Avenue, Rockville,MD 20852.

ADAMHA is anr Equal Opportunity/Affirmative Actiotn Employer.

POSITIONS OPEN

FACULTY POSITIONSDEPARTMENT OF SURGERY

THE UNIVERSITY OF CHICAGO

The Department of Surgery at the University ofChicago wishes to invite applications and nominationsftr several tenure-track positions to be filled in the 1991to 1992 academic vear. Candidates should be Board-certified or Board-eligible in their specialty. In additionto general surgery, positions are available in cardiacsurgery, neurosurgery, oral and maxillofacial surgery,orthopaedic surgery, otolaryngology/head and neck sur-gery, pediatric surgery, plastic and reconstructive sur-gery, thoracic surgery, transplantation surgery, vascularsurgery, and urology. Responsibilities will include teach-ing, clinical and/or basic research, and patient care.Applications should include curriculum vitae, a list ofpublications, and the names of at least four individualsfrom whom letters of reference may be solicited. Whilewe have no formal deadline, we would appreciate receiv-ing applications by 15 October 1991. Please send appli-cations or nominations to:

George E. Block, M.D., Acting ChairmanDepartment of Surgery

The University of Chicago5841 South Maryland Avenue, Box 168

Chicago, IL 60637T-ie University ofChicago is ant Affirmative Action/Equal

Opportunity Employer.

POSTDOCTORAL POSITIONTHE WISTAR INSTITUTE

A postdoctoral position is available to characterize a

newlv discovered enzymatic activity, "RNA duplex un-windase" and to understand its physiological roles. Theactivity is very novel, capable of unwinding double-stranded RNAs by modifying many adenosine residuesto inosine and creating 1-U mismatched base-pairings.The activity is likely to affect/regulate the secondarystructures, processing, and turnover ofvarious eukanroticas well as viral transcripts [Nature, 337, 19-20 (1989);Cell, 56, 331 (1989)]. Applicants should have trainingin protein chemistry, biochemistry, or molecular biology.The Wistar Institute is located within the University ofPennsylvania campus, and is devoted to basic research.

Interested persons should send curriculum vitae, re-

prints, related experiences, and a list of at least threereferences to: Dr. Kazuko Nishikura, The Wistar Insti-tute, 36th and Spruce Streets, Philadelphia, PA 19104.An Equal Opportunity/Affirnative Action Employer.

POSTDOCTORAL POSITION. In muscle physi-ology/locomotion. My laboratory studies muscle func-tion during locomotion using kinematic analysis, musclemechanics, histology, EMGs, and electrophoresis. Skillin some of the above as well as computer programmingand electronics helpful. The University of Pennsylvaniahouses the Pennsylvania Muscle Institute, with many

working on cellular aspects of muscle contraction. Please

send/FAX curriculum vitae immediately to: Dr. LarryRome, Department of Biology, University of Penn-

sylvania, Philadelphia, PA 19104. FAX: 215-898-8780.

1632

POSITIONS OPEN

POSTDOCTORAL POSITION. Available to studygerm cells and early development in the mouse. Applywith curriculum vitae to: Dr. R. L. Brinster, School ofVeterinary Medicine, University of Pennsylvania,Philadelphia, PA 19104.

POSTDOCTORAL POSITION. Currently avail-able to study the molecular biology of mutagenesis inbakers' yeast. Work in progress is concerned with ana-lyzing cloned genes and gene products involved inmutagenesis, and with experiments using vectors thatcarry a single defined mutagenic lesion. Send curriculumvitae and three letters of reference to: Dr. ChristopherW. Lawrence, Department of Biophysics, Universityof Rochester Medical Center, Rochester, NY 14642.Equal Opportunity/Affirmative Action Employer.

TWO POSTDOCTORAL POSITIONS. Availablein the Department of Physiology. Research areas are: (i)cell biology of lung microcirculation; hormonal regula-tion macromolecular transport, calcium imaging andeicosanoid metabolism in endothelial monolayers (Dr.Richard C. Schaeffer); and (ii) regulatory mechanisms insystemic microcirculation; metabolic studies in tissuewith optical techniques, electrophysiology of blood ves-sels, tissue oxygen exchange, cellular mechanisms ofregulation (Dr. Paul C. Johnson). Start dates and salariesnegotiable. Applications from U. S. citizens or permanentresidents will be accepted until positions are filled on 1March 1992, whichever is earlier. Send curriculum vitaeand three letters of reference to Drs. Schaeffer orJohnson, c/o

Department of PhysiologyCollege of MedicineUniversity of ArizonaTucson, AZ 85724

The University ofArizona is an AffirmativeAction/EqualOpportunity Employer. Female and minority members areurged to apply.

GLYCOLIPID-ANCHORED PROTEINS

POSTDOCTORAL POSITION. To study bio-chemical and cell-biological aspects of the biosynthesis ofglycophospholipid-anchored membrane proteins. Sendcurriculum vitae, two letters of recommendation, andtranscripts to: A. M. Tartakoff, Pathology, Case West-ern Reserve University School of Medicine, 2085Adelbert Road, Cleveland, OH 44106.

POSTDOCTORAL POSmIION. In molecular biol-ogy to study aging of human fibroblasts and C. elegans.Duties (experience essential) are to culture cells, preparenuclear extracts, and assay recA and related activities; toprepare and screen genomic libraries in plasmid, lambdaand YAC vectors; and to prepare/analyze aging cohorts.Salary $22,307 per year; 40 hours per week. Sendresume to: Employment Services Division, P.O. Box34047, Little Rock, AR 72203. Job order #538680.Must have proof of legal authority to work in the UnitedStates.

POSTDOCTORAL POSITION AT THE UNI-VERSITY OF CONNECTICUT. To join a multidis-ciplinary research group to study molecular mechanismof mutagenesis induced by chemical carcinogens using asite-specific approach. Ph.D. in one of the chemical orbiomedical areas with experience in basic molecularbiology techniques is required. Salary $22,000 per yearor more depending on qualifications. Send curriculumvitae and the names of three references to: ProfessorAshis Basu, University of Connecticut, Departmentof Chemistry, U-60, Storrs, CT 06269-3060. Affir-mnative Action/Equal Opportunity Emnployer. (Search#1A242.)

POSTDOCTORAL POSITION IN REPRO-DUCTIVE ENDOCRINOLOGY. This unique op-portunity in the Reproductive Endocrine Unit of Mas-sachusetts General Hospital (Harvard Medical School)combines basic research on local regulators of gonadalphysiology with clinical application of results to under-standing disease states. The specific project involvescharacterization and regulation of posttranslational pro-cessing of inhibin subunits using a variety of biochemicaland molecular techniques. Applicants should have expe-rience in either protein purification and characterizationor molecular biology. Send curriculum vitae, statementof research goals, and names of three references to: Dr.Alan Schneyer, Ph.D., Reproductive Endocrine Unit,Massachusetts General Hospital, Boston, MA 02214.

SCIENCE, VOL. 251

POSTDOCTORAL POSITIONSWALTHER ONCOLOGY CENTER

INDIANA UNIVERSITYSCHOOL OF MEDICINE

Postdoctoral positions are available to studythe molecular and cellular biology of two newlyisolated lymphokines, IL-9 and IL-il.

Candidates with a Ph.D. degree interested inapplying contemporary techniques of molecularbiology and receptor biochemistry to understandthe role of these growth factors should send theircurriculum vitae and addresses of three refer-ences to:

Dr. Yu-Chung Yang, Walther OncologyCenter, Indiana University School of Medi-cine, Room 540 Medical Research and Li-brary Building, 975 West Walnut Street, In-dianapolis, IN 46202.

Candidates with background in molecular bi-ology or biochemistry will be preferred althoughnot required for these positions.

Walther Oncology Ceniter is anl Equal Opportu-ttity Employer.

GIS MANAGERNATURAL RESOURCES RESEARCH INSTITUTE

UNIVERSITY OF MINNESOTA, DULUTHThis is an academic position which is open at the level of Research Fellow (M.S./M.A.) orResearch Associate (Ph.D.)

Illnimum Ouawifiutions: M.S./M.A. degree in geography, computer science or relatedfield with coursework and/or significant experience in Geographic Information Systems(GIS) and computer programming. M.S./M.A. or Ph.D. degree must be completed bystarting date of appointment.Desired Otailications: M.S./M.A. or Ph.D. degree in geography, computer science, orrelated field with coursework emphasis in Geographic Information Systems (GIS),computer cartography, computer programming, remote sensing, and quantitativemethods. Working knowledge of DOS, UNIX, and VMS operating systems. Two or moreyears experience with: 1) GIS software, particularly ARC/INFO and ERDAS, 2) worksta-tion and microcomputer operation, and 3) peripherals required for entering and plottingmapped data. Some experience in computer programming (ARC/INFO AML, C).Demonstrated ability to provide training/teaching.Responsibilitles: Manage an academic GIS facility, established through an NSFBiological Facilities Grant, which specializes in the application of GIS to ecological andnatural resources research. Work with principal investigators to develop GIS methodsand applications. Maintain equipment and software. Develop and document GISprocedures and programs to facilitate GIS use. Train new users of the facility.Appointment., Initial appointment will be for two years beginning summer 1991.Continuation based on performance.Send an application letter and current resume, and the names, addresses, and telephonenumbers of three references to:

Gis Manager Search CommitteeNatural Rmources Research institute

University of Minnesota, Duluth5013 Miller Trunk Highway

Duluth, MN 55811Applications must be postmarked by June 15, 1991. Writing samples may be requestedat the time of interview.

The University of Minnesota is committed to the policy that all persons shall have equalaccess to its programs, facilities, and employment without regard to race, religion, color,sex, national origin, handicap, age, veteran status, or sexual orientation.

Protein ChemistBiochemist

The Biomedicine and Health Program at the AustralianNuclear Science and Technolo Organisation is seekingoutstanding individuals to developradioimmunopharmaceuticals for diagnosis with PET andSPECT, and for therapeutic applications. Successfulapplicants will form a multi-interdisciplinary teamaddressing needs of Australian nuclear medicine.Our goal is improving health care delivery throughinnovative research, market-driven product development,and global collaboration with academia and industry.The National Medical Cyclotron and the joint Ansto/RPAHPET Centre will be commissioned at the Sydney locationduring 1991. A medical cyclotron and PET will be installedat Austin Hospital, Melbourne in 1992.Applicants must have a PhD preferably with 1-3 yearspostdoctoral experience in protein, immuno or biochemistry.For permanent appointments applicants must be Australian

citizens. Opportunities for sabbatical and term contracts arealso available.Expressions of interest along with resum6 nominating3 referees should be sent to:Dr R.M. Lambrecht, Director, Biomedicine & HealthProgram, PMB 1, Menai, NSW 2234, Australia.Phone: 61 2 543 3939. Fax: 61 2 543 9262.

ANSTO is an Equal Opportunity Employer.Smoking in the workplace is prohibited.

OhnstoAUSTRALIAN NUCLEAR SCIENCE& TECHNOLOGY ORGANISATION

Now you can pay for your line classifiedad with a credit card -we accept

MasterCard and VISA.

Please let us know on your ad order thatyou wish to take advantage of thisservice, or ask us for further details.

SCIENCE Classified AdvertisingTel: 202-326-6555 FAX: 202-682-0816

Univax Biologics Inc.'s primary objective is the development of newvaccines for the use in the production of intravenous immunoglobulin fortherapeutic and prophylactic treatment of life threatening infectious dis-eases. The Company is now seeking to significantly expand its researchand development group and is seeking ambitious and dedicated individualsin the following areas:Project Leader-Vaccine DevelopmentRespnsible for the activities involved with the development and validationof a vaccine for bacterial disease. The successful candidate will have atleast three years' experience in vaccine development with a good workingknowledge of antigen purification & characterization as well as conjuga-tion & process validation. Demonstrated ability to manage a group of 3-5individuals and the capability of managing interactions with key resourcesboth within and outside the Company.

Organic ChemistWe are seeking a Ph.D. level organic chemist with a demonstrated abilityto develop and validate new methods for synthesizing a variety ofimmunogens and polysaccharide-protein conjugates. Previous experi-ence in a GMP setting and direct experience with polysaccharides arehighly desirable.

Carbohydrate ChemistWe are seeking a Ph.D. level carbohydrate chemist with a background inthe immunology and immunochemistry of polysaccharides. Ability tocharacterize polysaccharides and lipopolysaccharides and standardizemethods of purification and large scale production is essential.

Research TechnicianThe Company is looking for several individuals to provide technicalsupport for vaccine development programs. Individuals with either a B.S.or M.S. in biology, biochemistry, microbiology, or immunology, andseveral years' experience are invited to apply. Working knowledge ofELISA, in vitro cell assays, antigen purification, and immunochemistry isdesirable.

Univax Biologics Inc. offers a dynamic work environment, a competitivesalary and benefits program, and equity participation plans. We are anequal opportunity employer. Send resumes to 12280 Wilkins Avenue,Rockville, Maryland 20852.

VETERINARY MEDICALOFFICER/TOXICOLOGIST

GM-15(Salary Range: $61,643 - $80,138)

Or

VETERINARY MEDICALOFFICER/TOXICOLOGIST

GM-14(Salary Range: $52,406 - $68,129)The Division of Toxicology Research andTesting (DTRT), an operating componentof the National Toxicology Program(NTP), is seeking applicants for apermanent position as Veterinary MedicalOfficer/Toxicologist, GM-15 to serve asHead, Study Design Group or asVeterinary Medical Officer/Toxicologist,GM-14, to serve as scientist in theChemical Carcinogenesis Branch (CCB).The CCB sets priorities, designs,conducts, evaluates and reports long-term toxicity and carcinogenicityevaluations in rodents on chemicals ofenvironmental concern. A majority of thestudies are performed in laboratoriesunder contract to the NTP but has limitedin-house research capabilities for short-term and long-term studies. The NTPdisseminates the results of its long-termand short-term studies to othergovernment agencies and the scientificcommunity through the publication ofNTP Technical Reports and bypublications in the scientific literature.The selectee, depending on his/herbackground will also assist inpharmacokinetics, chemical selection,monitoring of the laboratories conductingthe studies or in the evaluation andreporting of the studies. The selectee willinteract with chemists, toxicologists,pathologists and with other disciplineleaders within DTRT and with scientistsfrom government regulatory agencies,private industry and consumer groups onthe chemistry, design, or evaluation ofNTP long-term toxicity and carcino-genicity studies on environmentalchemicals and their potential to behazardous for man. The selectee willalso be expected to participate in studiesthat will aid in our understanding of rodentcarcinogenicity studies and theirrelevance for hazard identification forman. The incumbent must possess aDVM, Sc.D., MD, Ph.D., or equivalent intoxicology, pathology or related field andsignificant research experience. Boardcertification (ABT) or ACVP is desirablefor the scientist position but required forHead of Study Design. U.S. citizenship isrequired.For additional information, contact NormaDaye or Lisa Rogers at 919-541-7811. Toapply, submit curriculum vitae and thenames of three references by May 3,1991 to:

Norma Daye (Code: HNV27)NIEHS Personnel Office

PO Box 12233Research Triangle Park,

NC 27709

NIH is an Equal Opportunity Employer

POSITIONS OPEN

POSTDOCTORAL POSITIONA postdoctoral position is available to study genetic

abnormalities in urologic malignancies. Expertise in mo-lecular genetics is required. Send curriculum vitae andthree letters of reference to: Dr. John Libertino, LaheyClinic Medical Center, Departnent of Urology, 41Mall Road, Burlington, MA 01805. Equal OpportunityEmployer.

POSTDOCTORAL POSITION IN VISUALNEUROSCIENCE. Available in laboratory studyingneural circuits (and neurotransmitters) ofvisual thalamusand cortex by means of neuroanatomical (LM, EM),immunocytochemical and electrophysiological tech-niques. Experience in these techniques preferable. Sup-port available for 3 years. Send curriculum vitae andnames of three references to: Dr. V. M. Montero,Department of Neurophysiology, University of Wis-consin, 621 Waisman Center, Madison, WI 53705.An Affirmative Action/Equal Opportunity Employer.

POSTDOCTORAL POSITION IN MOLECU-LAR BIOLOGY. Available immediately to developprogram to humanize and modify murine monoclonalantibodies. Experience in cloning, sequencing, and mam-malian cell expression required, working knowledge ofimmunogenetics desirable. Send curriculum vitae to: Dr.Roberto Ceriani, John Muir Cancer and Aging Re-search Institute, 2055 North Broadway, WalnutCreek, CA 94596.

An Equal Opportunity Employer.

POSTDOCTORAL POSITION IN MOLECU-LAR GENETICS OF HYPERTENSION. Is avail-able for the identification and characterization of genescontrolling blood pressure in genetically hypertensiverats. Techniques include library construction, cloning,RFLP analysis, sequencing, transgenic animals, etc. Ap-plicants must have Ph.D., M.D., D.V.M., or equivalentdegrees and be citizens or permanent residents ofthe UnitedStates. Experience in microbiology, genetics, or molecu-lar biology is desirable. Send curriculum vitae to: Dr.John Rapp, Department of Medicine, Medical Col-lege of Ohio, C.S. 10008, Toledo, OH 43699. AnEqual Opportunity Employer.

POSTDOCTORAL POSITION. Available imme-diately to join an interdisciplinary research group inves-tigating the role of monoamines in function recoveryafter brain injury. Candidates should have experiencewith HPLC and/or microdialysis. Funding is for 3 yearswith opportunity for appointment as senior researchassociate. Send statement of research interests, curricu-lum vitae, and names of three references to: Dr. D. M.Feeney, Department of Psychology, The University ofNew Mexico, Albuquerque, NM 87131. Telephone:505-277-8946; FAX: 505-277-1394.An Equal Opportunity/Affirmative Action Employer.POSTDOCTORAL POSITION IN MOLECU-

LAR BIOLOGY OF PRIMATE POLYOMAVI-RUSES. Investigation of molecular biology of polyoma-virus persistence and transformation of permissive andhuman cells. Applicants must have completed Ph.D. invirology or molecular biology. Send curriculum vitae,statement of interests, and three letters of recommenda-tion to: Frank O'Neill, Ph.D., University of Utah,Department CVMB and VA Medical Center (i5lE),Salt Lake City, UT 84148.

SYSTEMS PHYSIOLOGY-BIOMEDICAL EN-

GINEERING. Department ofAnesthesiology and Crit-

ical Care Medicine, Johns Hopkins University, has an

opening for POSTDOCTORAL or INSTRUCTORLEVEL PHYSIOLOGIST or BIOMEDICAL EN-

GINEER to work on NIH-funded studies relatingcardiovascular respiratory interactions, splanchnic blood

flow and sepsis including computer modeling. Collabo-rative studies ongoing with multiple basic science and

clinical groups on a wide range of subjects. Substantial

achievement with evidence of independent abilities will

lead to consideration for a tenure-track position. Send

curriculum vitae, names of references, and a brief state-

ment of research experience and interests to: James L.

Robotham M.D., Director of Pulmonary Anesthesi-

ology Laboratory, Department of Anesthesiology/

CCM, Blalock 15, Jo Hopkins Hospital, 600

North Wolfe Street, Baltimore, MD 21205. TheJohnsHopkins University School ofMedicine is an Equal Oppor-tunity/Affirmative Action Employer.

POSITIONS OPEN

POSTDOCTORAL POSITION. At Oak RidgeNational Laboratory (ORNL) to do research on ultra-sensitive detection techniques as applied to DNA se-quencing problems. Degree in analytical/physical chem-istry or applied physics with background in opticalspectroscopy preferred; should have experience withlasers and optics and background in instrumentation. Forposition information, contact: J. Michael Ramsey,ORNL, P.O. Box 2008, Oak Ridge, TN 37831-6142. For application material, contact: PostgraduateResearch Prosam/Genome, Science/Engineering Ed-ucation Division, Oak Ridge Associated Universities,P.O. Box 117, Oak Ridge, TN 37831-0117. Tele-phone: 615-576-3456.

POSTDOCTORAL POSITIONSIN GENE THERAPY

Somatix Therapy Corporation is a leading biotechnol-ogy company developing programs in gene therapy andcellular transplantation. Postdoctoral positions are avail-able for recent Ph.D.'s to work in the area of retroviral-mediated gene transfer in mammalian cells. Candidatesshould have experience with retroviruses, primary cellculture, and recombinant DNA techniques. Please sub-mit curriculum vitae to: Department #19, PersonnelDepartment, Somatix Therapy Corporation, 850 Ma-rina Village Parkway, Alameda, CA 94501. EqualOpportunity Employer.POSTDOCTORAL-MARINE POPULATIONS

Quantitative biologist with experience in modelingand analysis of population dynamics involving environ-mental forcing and spatial structure. Requires the abilityto integrate information from physical oceanography,physiological ecology, and population biology, and somefacility with implementing computer simulations of pop-ulation models. Familiarity with marine systems andoceanography of the California Current will be an asset.Interested parties please sent letter of application, curric-ulum vitae, and three letters of reference to: Louis W.Botsford, Center for Population Biology, Universityof California, Davis, CA 95615, by 1 May 1991. TheUniversity of California is an Affirmative Action/EqualOpportunity Employer.ASSOCIATE-POSTDOCTORAL POSITIONApplications are invited for a postdoctoral position as

an associate to work in the laboratory of Dr. RobertNussbaum, whose current research involves studies ofX-linked human disease, using genomic approaches.Projects include investigation of Lowe Syndrome, Frag-ile X Syndrome, and physical mapping studies using yeastartificial chromosomes, pulse field gel analysis, andcDNA cloning and analysis. Qualified candidates shouldpossess a Ph.D. in molecular biology or genetics. Pleaseforward your curriculum vitae and three letters of rec-ommendation to: Dr. Robert Nussbaum, University ofPennsylvania School of Medicine, 422 Curic Boule-vard, Philadelphia, PA 19104-6145. We are an EqualOpportunity Employer.POSTDOCTORAL POSMIIONS. Now available

to study the molecular biology of proteolytic processingenzymes required for synthesis of peptide hormones andneurotransmitters. This project involves molecular clon-ing and expression of proteases involved in processingenkephalin, tachykinin, and other neuropeptide precur-sors. Experience in molecular biology and/or protein/peptide biochemistry are required. Candidate shouldhave recently obtained a Ph.D. in biochemistry, molec-ular biology, molecular neurobiology, or appropriatediscipline. Please send curriculum vitae and names ofthree references to: Dr. Vivian Hook, Department ofBiochemistry, Uniformed Services University of theHealth Sciences, Bethesda, MD 20814.

POSTDOCTORAL FELLOW. A position is opento study the effects of ethanol and other drugs of abuseon the immune system. Areas of research include im-mune mechanisms of resistance to infectious agentsincluding bacteria and viruses, T- and B-cells interac-tions, in vitro and in vivo molecular aspects of T- andB-cell activation, and T-dependent antibody productionto defined antigens. A Ph.D., in immunology/microbiol-ogy is preferred. Send curriculum vitae and the names ofthree references to: Dr. Thomas R. Jerrells, Depart-ment of Cellular Biology and Anatomy, LouisianaState University Medical Center at Shreveport, P.O.Box 33932, Shreveport, LA 71130-3932. An Affir-mative Action Employer.

SCIENCE, VOL. 251l a

POSITIONS OPEN

POSTDOCTORAL FELLOW POSITIONS inneuroscience at the Addiction Research Center. Topicsof research include: characterization and purification ofdrug and neurotransmitter receptors: cocaine receptors;neurotransmitters of reward and addiction; effects ofdrugs on neurotransmitter systems. Salaries range from$29,000 to approximately $49,000 depending on expe-rience and qualifications. Benefits and relocation expens-es may be available. Previous postdoctoral experiencedesirable but not necessary. Send curriculum vitae to:Dr. Michael J. Kuhar, NIDA Addiction ResearchCenter, P.O. Box 5180, Baltimore, MD 21224. TheAlcohol, Drug Abuse and Mental Health Administration isan Equal Opportunity Employer. ADAMHA is smoke-freeand drug-free.

POSTDOCTORAL FELLOWSHIPS. Departmentof Cellular and Developmental Biology and Organismicand Evolutionary Biology, Harvard University. A limitednumber of postdoctora research positions become avail-able from time to time. Some appointments are fundedthrough research grants awarded to faculty members andare ordinarily for 1 year, sometimes renewable, otherappointments are possible through postdoctoral fellow-ships. For a list of faculty members who have postdoc-toral positions available, write to the respective depart-ment office: Harvard University, 16 Divinity Avenue,Cambridge, MA 02138. (Do not send applications).Harvard University is an Equal Opportunity/AffirmativeAction Employer.

POSTDOCTORAL FELLOWSHIPS IN MO-LECULAR NEUROIMMUNOLOGY AND NEU-ROIMMUNOMODULATION at the University ofAlabama at Birmingham are available 1 July 1991,supported by an NIH Training Grant for basic scientistsor clinicians to conduct research on the molecular basis ofneuroimmunology, neuroimmunomodulation, and thebidirectional communication between the nervous andimmune systems. Preceptors and areas of interest are asfollows: E. N. Benveniste, Ph.D. (cytokines and glia): J.E. Blalock, Ph.D. (neuroimmunomodulation: lympho-cyte-derived hormones); E. J. Dropeho, M.D. (parane-oplastic neurological disorders); M. L. Egan, Ph.D.(immunoregulation and natural killer cells); G. Y.Gillespie, Ph.D. (immune response to glial tumors); J. D.Neill, Ph.D. (neuro-endocninology); D. A. Weigent,Ph.D. (growth hormone and the immune system); and J.N. Whitaker, M.D. (immunochemistry and degradation ofmyelin basic protein). Interested applicants should submita letter stating their specific interests, curriculum vitae, andnames of three references by 20 April 1991 to: John N.Whitaker, M.D., Department ofNeurology, Universityof Alabama at BRmingham (UAB), Birmingham, AL35294. Telephone: 205-9342402. UAB is an Affirma-tive Action/Equal Opportunity Employer.

POSTDOCTORAL FELLOWSHIPS FORTRAINING IN IMMUNOLOGY AND VIROLO-GY AT THE UNIVERSITY OF MASSACHU-SEITS MEDICAL CENTER. Cellular immunology:Robert E. Humphreys, M.D., Ph.D.; Lawrence Jung,M.D.; Alan D. Michelson, M.D.; Carol L. Miller, Ph.D.;David C. Parker, Ph.D.; Paul L. Romain, M.D.; RobertT. Woodland, Ph.D. Viral immunology: Neil R. Black-low, M.D.; Francis A. Ennis, M.D.; John E. Herrmann,Ph.D.; Ichiro Kurane, M.D.; Takeshi Sairenji, Ph.D.;John L. Sullivan, M.D.; Raymond M. Welsh, Ph.D.Experimental diabetes: Michael C. Appel, Ph.D.; ArthurA. Like, M.D.; Aldo A. Rossini, M.D.; Bruce A. Woda,M.D. Molecular virology: Christie A. Holland, Ph.D.;Trudy G. Morrison, Ph.D.; Carel Mulder, D. Phil.;Ronald M. Iorio, Ph.D.; Harriet L. Robinson, Ph.D.Molecular immunology: Simon K. Lawrence, Ph.D.;John E. Mole, Ph.D.; Peter E. Newburger, M.D.; JanetStavnezer, Ph.D. Candidates interested in joining thisactive, multidisciplinary, NIH-supported training pro-gram should send a resumd, the names of three refer-ences, and a letter stating their research interests and thelaboratories in which they would be interested in under-taking training to: Dr. Harriet Robinson, Departmentof Pathology, University of Massachusetts MedicalCenter, Worcester MA 01655. The University ofMas-sachusetts Medical Center is an Affirmative Action/EqualOpportunity Employer.

29 MARCH 1991

11 M

Join Wyeth-Ayerst Research, one of the world's largest pharmaceutical research anddevelopment groups. Now is your opportunity to become an integral member of ourfast-paced, innovative team at our modern researchfacility in Prnceton, NJ.

CARDIovA.......IE S ]

LA TABOLIC

RCH Gl ULiar Neurobolog y'ch Scientist - Eh.D.

An opportunity exists for a Ph.D. with 3-5 years post-doctoral experi-ence in the use of molecular biological techniques applied to neu-ronal systems, to join a growing team of scientists involved in thecloning and expression of receptors/channels and their study. Theideal candidate will have direct experience in designing and optimiz-ing prokaryotic and mammalian expression systems, PCR amplifica-tion and site-directed mutagenesis. Familiarity with transcriptionalregulatory factors and/or second messenger systems is also desir-able. The candidate will interact with a broadly trained group of bio-chemists, electrophysiologists and pharmacologists to implementnew drug discovery efforts in the CNS area. We are seeking applicantswith a strong history of scientific achievement and a demonstratedability to conduct innovative research. Position #317.

Ion Channel ResearchResearch Scientist - Ph.D.

We are seeking a candidate with a Ph.D. in Physiology, Pharmacologyor Biophysics with 3-5 years relevant post-doctoral experience to joinan active research program in the study of ion channels and theirmodulation by drugs. The ideal candidate will be expert in the use ofpatch clamp techniques applied to the study of voltage-gated and/ormetabolically activated K+ channels at both whole cell and singlechannel levels, and will interact with an interdisciplinary team of car-diovascular and neuroscientists engaged in the design and discoveryof new therapeutic agents. Candidates should be familiar with mem-brane current measurements in freshly dissociated neuronal cellpreparations and the use of oocyte and mammalian cell expressionsystems. Candidates should be capable of conducting an independentresearch program and maintaining a high level of productivitythrough scientific publications. Position #300.

Pharmacologist - B.S./M.S.An opening exists for a B.S. candidate with 3-5 years experience or anM.S. candidate with 2-4 years experience to conduct cellular electro-physiology studies using whole cell and single channel patch clamptechniques. The candidate will be well trained in methods of dissoci-ating and maintaining single cells from cardiac or neural prepara-tions, and expert in the measurement of whole cell currents.Familiarity with computer-based data acquisition and analysis isrequired. Experience with single channel recordings a plus. The can-didate will become an integral part of a well-established interdisci-plinary research effort aimed at designing novel drugs targeted at ionchannels. Independence and professional growth will be stronglyencouraged through direct participation in internal research meet-ings and the publication of original research findings. Position #333.

We offer an excellent compensation and benefits package. Forwardresume and salary requirements, stating appropriate position num-ber, to: Wyeth-Ayerst Research, Personnel Manager, CN 8000,Princeton, NJ 08643-8000. An Equal Opportunity Employer, M/F/H/V.Principals only.

^ v WYETHAYERST

TM

SCIENCE welcomes placement of line classified adsby FAX. Please include name and telephone number forour confirmation call when transmitting ad to:

FAX NUMBER: 202-682-0816

1 1

POSITIONS OPEN

POSTDOCTORAL FELLOWSHIP. Available im-mediately for molecular biologist with recent Ph.D. towork on the expression of mammalian antibodies innonmammalian systems. Applicants should have experi-ence in molecular cloning techniques: a working knowl-edge of immunology/protein chemistry would be advan-tageous. The appointment is for a 2-year period at asalary of approximately $32,000 Canadian. Please sendcurriculum vitae and references to: Dr. G. C. Randall,Animal Diseases Research Institute, P.O. Box 11300,Station "IH, Nepean, Ontario K2H 8P9 Canada.

PREDOCTORAL FELLOWSHIPS AND RE-SEARCH ASSISTANTSHIPS. Opportunities existfor cross-disciplinary research projects on microbial bio-films in a unique work environment with students inother disciplines. Students will work toward degreeprograms in microbiology, chemistry, or engineering inthe newly established National Science Foundation Cen-ter for Interfacial Microbial Process Engineering. Annualstipends range from $10,000 to $13,0 per year withtuition remission. Submit inquiries to: Dr. John Sears,Department of Chemical Engineering or Dr. GillGeesey, Department of Microbiology, Montana StateUniversity, Bozeman, MT 59717.

POSTDOCTORAL FELLOWUNEXPECTED OPENING FOR JULY 1991M.D. or Ph.D. interested in exciting laboratory re-

search in gene therapy project using human bone marrowcells and animal models. Must be a United States citizen orpermanent resident. Salary commensurate with experience.Send resume to: Dr. Arthur Bank, Columbia Univer-sity College of Physicians and Surgeons, HHSC1602, 701 West 168th Street, New York, NY 10032.Columbia is an Equal Opportunity Employer.

ALCOHOL-DRUG,CULTURAL PSYCHIATRY, AND

GERIATRIC PSYCHIATRY FELLOWSHIPSThe Department ofPsychiatry and Behavioral Sciences

at the University ofOklahoma Health Sciences Center isoffering 1- and 2-year fellowships in alcohol-drug, cul-tural, and geriatric psychiatry for PGY4 and -5 psychi-atric physicians. Send correspondence, including resumeand three letters of reference, to: Joseph Westermeyer,M.D., Ph.D., Chair, Department of Psychiatry andBehavioral Sciences, University of Oklahoma HealthSciences Center, P.O. Box 26901, Oklahoma City,OK 73190-3048. The University of Oklahoma is anAffirmative Action/Equal Opportunity Employer.

POSTDOCTORAL FELLOWPosition open for scientist with background in bio-

chemistry to join an active group studying the mecha-nisms of atherosclerosis at the molecular and structurallevel. Areas of vascular biology to be studied include therole of growth factors, cytokines, eicosanoids, G-pro-teins, and lipoproteins in the disease process. Positionoffers excellent opportunity for collaboration and ad-vancement to a faculty position. Fellows will be appoint-ed for a 2-year term beginning 1 July 1991; stipends willbe funded by our on-going NIH training program inCardiovascular Biology. Requirements are a Ph.D. orM.D. and U.S. citizenship or permanent residency. Pleasesend curriculum vitae and names and addresses of threereferences to: Dr. David P. Hajjar, Professor of Bio-chemstry and Pathology, Director, NIH TProgram, Cornell University Medical Colleg1York Avenue, New York, NY 10021. Equal Opportu-nity/Arffrmative Action Employer.

Address or contact the following person if there areany questions:

Dr. David P. HajjarDepartment of PathologyCornell Medical School1300 York Avenue

New York, NY 10021Telephone: 212-746-6470

POSTDOCTORAL RESEARCH POSITIONReceptor biochemistry of brain in prion diseases.

Salary supported by NIH training grant. Requires U.S.citizenship or permanent resident visa. The University ofCalftornia is an Equal Opportunity/Affirmative Action Em-ployer. Women and minorities are encouraged to apply. Sendcurriculum vitae and three letters of recommendation to:Stephen J. DeArmond, Neuropathology, Universityof California, San Francisco, CA 94143-0506.

1636

POSITIONS OPEN

> Agrcltural United States< Research Department of

Svie AgriculturePOSTDOCTORAL RESEARCH ASSOCIATE.

Immediately available with the Protozoan Diseases Lab-oratory, Beltsville, Maryland, to investigate the role ofthe recombinant avian lymphokines in avian immunesystem and in poultry diseases. Candidate must have aPh.D. in biochemistry, immunology, or molecular biol-ogy. Salary is commensurate with experience ($31,116 to$40,449 peer annum). Send applications (SF-171) to:Dr. H. Lillehoj, United States Department of Agri-culture, Agricultural Research Service, ProtozoanDiseases Laboratory, Building 1040, Room 100A,BARC-East, Beltsville, MD 20705-2350 or tele-phone: 301-344-1771. Applications should be marked5015 and received by 1 July 1991. An Equal Opportu-nity Employer.

POSTDOCTORAL RESEARCH ASSOCIATE.Position is immediately available to investigate novelregulation of human fallopian tube functions by growthfactors and gonadotropins. Experience in measurementsof ciliary motility, smooth muscle contractions, cell divi-sion and secretory functions, cell dispersion and cellculture techniques is desirable. If interested, contact: Dr.Ch. V. Rao, Department of Obstetrics/Gynecoloy,438 MDR Building, University of Louisville, Louis-ville, KY 40292. FAX: 502-588-0881.

NIH HEART, LUNG AND BLOOD INSTITUTEPOSTDOCTORAL RESEARCH POSITION.

Immediately available for M.D. or Ph.D. with training inmolecular genetics or relevant experience. Excellent op-portunity to pursue molecular biology and gene mappingof hypertrophic cardiomyopathy. Must be within 3 yearsof hav completed doctoral training. Send curriculumvitae and name of three references to: Dr. Neal Epstein,National Heart, Lung, and Blood Institute, Building10, Room 7C103, 9000 Rockville Pike, Bethesda,MD 20892.

NIH is an Equal Opportunity Employer.

ASSOCIATE-POSTDOCTORAL POSITIONApplications are invited for a postdoctoral position as

an associate to work in the laboratory of Dr. James M.Wilson at the University of Michigan Medical Center,whose current research involves studies of liver genereplacement therapies. Qualified candidates should pos-sess either an M.D. or Ph.D. with research experience incell/molecular biology. Please forward your curriculumvitae and three letters of recommendation to: Jim Alford,Jr., Manager of Administrative Services, 1150 WestMedical Center Drive, 4544 MSRB II, Ann Arbor, MI48109-0650. An Equal Opportunity Employer.

MOLECULAR GENETICSA postdoctoral fellowship position is available imme-

diately to study the molecular genetics of pediatric braintumors. Initial research will focus on loss of heterozygos-ity on chromosomes 17p and 22q and PCR-based se-quencing of p53. Experience in molecular biology isrequired.Excellent working environment in new labora-tory space at The Children's Hospital of Philadelphia, onThe University of Pennsylvania campus. Send letter,curriculum vitae, and names of three references to: Dr.Jaclyn Biegel or Dr. Beverly Emanuel, Division ofHuman Genetics and Molecular Biology, The Chil-dren's Hospital ofPhiladelphia, 34th Street and CivicCenter Boulevard, Philadelphia, PA 19104 or FAX:215-590-3850.

POSTDOCTORAL/RESEARCH ASSOCIATEMOLECULAR BASIS OF PROSTATE CANCERPositions available to study the molecular basis of

prostate cancer development and metastasis in humans.Current approaches involve the use of a novel transfec-tion/expression system to transfer and identify new hu-man tumor-inducing genes and to develop monoclonalantibodies specific for tumor-associated antigens. Exper-tise in current molecular biological techniques, such ascDNA cloning, library screening and PCR required. Toapply, send curriculum vitae, statement of research goalsand three letters of reference to: Dr. P. B. Fisher,Deeartments of Pathology and Urology, ColumbiaUniversity, College of Physicians and Surgeons, 650West 168th Street, New York, NY 10032. FAX:212-305-5498. Equal Opportunity Employer.

POSITIONS OPEN

POSTDOCTORAL RESEARCH ASSOCIATETo participate in ongoing program analyzing the

neural regulation of circadian rhythms and the effects ofaging on the circadian timing system. Candidate musthave a Ph.D. or the equivalent and experience in eitherelectrophysiology of single units in hypothalamic slicesor immunocytochemistry of nervous tissue includingelectron microscopy. Experience in circadian biology isdesirable. Send curriculum vitae and names of threereferences to: Dr. Robert Y. Moore, Center for Neu-roscience, University of Pittsburgh, BST W1657,Pittsburgh, PA 15261. Equal Opportunity/AffirmativeAction Employer.

POSTDOCTORAL/RESEARCH ASSOCIATEPosition available on the biological function and bio-

chemistry of the Alzheimer Amyloid Precursor Protein(APP). Qualifications include a Ph.D. or M.D. with astrong background in cell biology and/or protein bio-chemistry. Experience with eukaryotic in vitro expressionsystems and nucleic acid sequencing desirable. The can-didate will be part of an effort to study the mechanism ofamyloid accumulation in the CNS. Our team is part ofthe Alzheimer disease research center of Mount SinaiMedical School which provides an excellent environmentfor basic research in this field. Salary range: $25,000 to$30,000. Please send resume and names of referees to:

Dr. Nikos K. RobakisMount Sinai School of MedicineDepartment of Psychiatry and

Fishberg Research Center for NeurobiologyBox 1229

One Gustave Levy PlaceNew York, NY 10029

SENIOR RESEARCH ASSOCIATE. In biologyto work at a university located in northeastern Ohio. Theduties include the identification and collection of diversegenetic material from an array of plant species, with aconcentration on pines, and identifying levels of diversityusing biochemical and molecular markers for a known setof genes in several populations; population and quanti-tative genetical interpretation of data, combined withstatistical analysis for subsequent publication in scientificjournals; traveling to collect needle samples and toconduct field studies on demographic structure, plantbreeding systems and estimation of site (ecological)qualities. Ph.D. in botany or genetics required. Noexperience required in above duties but applicants willqualify with 3 years postdoctoral experience in molecularand population genetics; 37.5 hours per week, 8:30 a.m.to 5:00 p.m., Monday through Friday; $32,500 perannum. Must have proof of legal authority to work perma-nently in the United States. Send r6sume, list of at least sixrefereed publications, transcripts and/or two letters fromacademic advisers in duplicate (no calls) to: J. Davies, JO#1255669/Ohio Bureau of Employment Services,P.O. Box 1618, Columbus, OH 43216.

Affirmative Action/Equal Opportunity Employer.

ASSOCIATE NEUROSCIENTIST. Neurophysi-ology and pharmacology of drug abuse research pro-gram. Participate in research and laboratory manage-ment. Teach and tutor graduate and postdoctoralstudents. Qualifications: M.D. and/or Ph.D.; minimumof 7 years of research in mammalian cellular electrophys-iology of in vivo and in vitro nervous system (intra- andextracellular recording, voltage-clamp and patch-clamptechniques); primary authorship of at least ten publica-tions in peer-reviewed journals; and graduate level teach-ing more than 5 years. Send curriculum vitae and threereference letters to: Rich Sessions, Administrative Of-fice, Vollum Institute, L474, Oregon Health SciencesUniversity (OHSU), Portland, OR 97201-3098.OHSU is an Equal Opportunity/Alfirmative ActionEmployer.

TRANSPLANTATION IMMUNOBIOLOGYThe Transplant and Immunogenetics Laboratory at

Oregon Health Sciences University is recruiting a recentgraduate of a Ph.D. program in immunology, who hashad at least one postdoctoral position, to conduct re-search in human immunobiology as it relates to organtransplantation. A recruitment package of salary, space,and start-up funds is available. The individual should beself-supporting within 3 years. Contact: D. J. Norman,M.D., Oregon Health Sciences University, 3181 S.W.Sam Jackson Park Road, Portland, OR 97201.

SCIENCE, VOL. 251

Bristol-Myrs Squibb

Pharmaceutical0searc nstit...te<aaoron0~~~~~~~~~~~~~............- ..... .....

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Bristol-Myers Squibb Pharm-aceuc.-|.l ResearchInstitute is continuing to expand .ourexensiveresearch efforts in the areas of cardiovscu

infectious and metabolic diseases. This expan-

sion has created several exceptional opportu-nities for Research Scientists at our Princeton,NJ and Wallingford, CT facilities.

PHARMACOLOGY(Princeton, New Jersey)Positions are available in the following areas:

* Experiment with anesthetized and consciousanimal preparations, especially canine models ofheart failure or hypertension, and performsurgery and statistical analyses. Reply toDept. 210A.

* Prepare perfusion solutions, microelectrodes andother apparatus for electrophysiologyexperimentation. You will also handle/providecare and dose small animals, collect and preparecardiac tissues for in vitro study. Reply toDept. 210B.

* Evaluate antithrombotic drugs in vivo and exvivo. Other responsibilities include surgery,platelet function and blood coagulation testing aswell as conducting experiments in animalmodels of thrombosis. Reply to Dept. 210C.

* Conduct experiments on the effect of novel agentson the atherosclerosis in vivo. Responsibilitiesinclude computer-based image analysis,vascular surgery, histology, electron microscopyand animal care. Reply to Dept. 210D.

Candidates for these positions should possess aBS or MS in a relevant scientific discipline alongwith several years research experience.

MICROBIAL MOLECULAR BIOLOGYNatural Products Program(Wallingford, Connecticut)* Ph.D. in Biochemistry or Microbiology and a mini-mum of 5 years experience in natural productsresearch required. Experience in microbial assaysand both thin layer and HPLC chromatography isessential. Experience in microbial fermentationswould be an asset. Reply to Dept. 210E.

* B.S. or M.S. in Biochemistry or Microbiologywith 1-2 years of experience in natural productsresearch required. A background in chromatog-raphy, both TLC and HPLC is desirable, as isexperience with microbial fermentations. Replyto Dept. 210F.

Please forward your resume (including dept.code#) to: Bristol-Myers Squibb PharmaceuticalResearch Institute, Human ResourcesDepartment, PO. Box 4000, Princeton, NJ08543-4000. An equal opportunity employer.

BristoL-Myers Squibb Company

3. American Society for Biochemistryand Molecular Biology

1991 Fall Symposium

Biological Significance of LipidModification of Proteins

October 11-14, 1991Keystone, Colorado

Organizers: Jeffrey Gordon, Washington UniversityPaul Englund, Johns Hopkins UniversityJohn Glomset, University of Washington

Speakers will be chosen from abstracts.Abstract Deadline: June 3, 1991

Registration and abstract information is available from:

ASBMB Symposium OfficeRoom 32069650 Rockville PikeBethesda, MD 20814-3998Tel: (301) 530-7010

CALL FOR PAPERSGENDER IN ACADEME: WHO CARES?

2nd BIENNIAL CONFERENCEOCTOBER 31-NOVEMBER 2, 1991

HOSTED BY UNIVERSITYOF SOUTH FLORIDATAMPA, FLORIDA

The conference committee seeks papers that will provide a lively forum ongender in academe to facilitate the exchange of theory and research.

Nationally recognized scholars, from the disciplines of sciences and appliedprofessions, humanities, and social sciences will address the conference.We invite scholarly research on the role of gender in higher education-its

significance in historical and contemporary contexts and for the future, includingscholarship that deals with:

-Women as teachers, scholars, researchers, administrators, writers, andstudents.

-Gender and the curriculum-what we learn, what we teach; how we writeand how we teach writing; overt and covert exclusion, bias, stereotyping;curricular revision and the effect of gender on methodology.*

-Intersection of gender, race, class, ethnicity, and disability in education.-Education-catalyst for change or protector of the status quo?

You are encouraged to submit a one-page, double-spaced abstract of yourwork that addresses some aspect of the conference theme. Please indicate theformat desired, e.g. individual paper, panel, symposium, workshop, etc.

*Planning is underway to publish selected conference papers on the specifictopic of Gender and the Curriculum. For publication consideration, pleasesubmit on this topic as described above.

SUBMISSIONS SHOULD BE POSTMARKED NO LATER THAN APRIL 15, 1991.

For abstract submission or further conference or information, contact:Lagretta LenkerUniversity of South Florida4202 E. Fowler AvenueLLL 012Tampa, FL 33620 (813) 974-2403The University is an Affirmative Action/Equal Opportunity Institution.

POSITIONS OPEN

CARBOHYDRATE BIOCHEMIST. RESEARCHSCIENTIST for small start-up company in Californiadeveloping novel oligosaccharide sequencing technology.Ph.D. or equivalent experience, knowledge of glycocon-jugate structure and experience with conventional sequenc-ing technology required. Competitive industrial salary andfringe benefits offered. Job requires staffing and laboratorysupervisory skills. Resumes to: Glyko, Inc., 81 DigitalDrive, Novato, CA 94949.

ANALYTICALULTRACENTRIFUGATION

Experienced professional to participate in develop-ment of instrument, data analysis software, and applica-tions methodologies. Must be able to communicate wellwith engineering and marketing professionals. Excellentpresentation skills required. Will travel and make presen-tations to scientific assemblies. Ph.D. in physical chem-istry or related field with related research experiencepreferred. Send resume with salarv history to: BeckmanInstruments, Professional Staffing, 1050 Page MillRoad, Palo Alto, CA 94304. Equal Opportunity Emn-ployer.

PHYSICIAN. The National Heart, Lung, and BloodInstitute is recruiting for a physician who is Board-certified in cardiology, and is an expert in carrying outstudies to determine forearm vascular blood flow andresistance. The candidate should have broad experiencein performing forearm plethysmography, in infusingdrugs intra-arterially, and in performing treadmill andbicycle exercise testing. The candidate must have exper-tise in the mechanisms responsible for the control ofvascular tone, including the role of the endothelium.Finally, the candidate must be expert in performing andinterpreting echocardiographic studies. Salarv range:$45,000 to $60,000. Contact: Dr. Stephen Epstein,Cardiology Branch, Building 10, Room 7B15, 9000Rockville Pike, National Institutes of Health, Be-thesda, MD 20892. NIH is an Equal OpportunityEmployer.

PHYSICIST. To work in Newport News, Virginia;40 hours per week, 8 a.m. to 5 p.m.; $42,000 to $44,000per year. The incumbent will lead the effort in the design,instrumentation, installation, and operation of highlysegmented large drift chambers to be used for chargedparticle tracking in the CEBAF Large Acceptance Spec-trometer (CLAS). Develop read-out electronics, electri-cal systems, cooling systems, gas distribution systems,experimental techniques, and instrumentation for theon-line monitoring of the drift chamber system and forthe off-line software analysis of the drift chamber hard-ware. Develop techniques for structural stability compu-tations and measurements. Requirements: Doctorateplus 4 years of work experience in experimental nuclearphysics. Previous experience installing, commissioning,and running highly segmented large-acceptance driftchambers for charged particle tracking at a particleaccelerator. Instrumentation expertise in layout of elec-tronics, cooling systems, gas distribution, and monitor-

ing systems for drift chambers. Experience in develop-ment of algorithms and use of Monte Carlo routines forcomputation of resolution, efficiency, track matching,and momentum reconstruction. Experience in develop-ment of software for on-line detector monitoring off-lineanalysis of chamber hardware performance and large-scale simulation of physics processes. To apply, mail or

hand-carry resume with copy of ad attached by 30 April1991 to: M. J. Hotchkiss, Virginia Employment Com-mission, 5145 East Virginia Beach Boulevard, Nor-folk, VA 23502. J.O. #VA0011196.

ASSISTANT RESEARCH IMMUNOLOGIST.Program in Transplant Immunology is offering a posi-tion for a molecular/cellular immunologist with expertisein human immunogenetics and transplantation immu-nology. Candidate must have a Ph.D. degree with at least3 years of postdoctoral employment and/or training in

human immunogenetics and HLA system involving:serology or cellular immunology, T cell cloning, molec-ular genetics as related to histocompatibiliry, immuno-

chemistry. Responsibilities will include: Studies on an-

tisense gene regulation, human tolerance induction, andimmune monitoring of transplant recipients. Salaryrange: $41,600 to $52,400 depending on experience.Send curriculum vitae and reference to: Marvin R.Garovoy, M.D., University of California, San Fran-cisco, 520 Health Sciences East, Third and ParnassusAvenues, San Francisco, CA 94143-0508.

POSITIONS OPEN

NEUROBIOLOGY/NEUROPATHOLOGYCLINICAL INVESTIGATOR

Position in Department of Laboratory Medicine andPathology, Mayo Clinic, Rochester, Minnesota. SeekingBoard-certified neuropathologist with primary commit-ment to basic neurobiological research and secondarycommitments to shared teaching and service responsibil-ities with other full-time neuropathologists. Candidateshould has e an established track record of successfulinvestigation in neurobiological/neuropathological re-search and experience in competing for grant support atnational/international levels. State-of-the-art facilities,space, equipment, start-up support and the extensiveresources of the Mayo Clinic research community will beavailable. Qualified candidates should submit detailedcurriculum vitae and bibliography to: B. W. Scheith-auer, M.D., Department of Laboratory Medicine andPathology, Mayo Clinic, Rochester, MN 55905.Mayo Foundation is ant Aflrtniative Actionz/Equal Opportt-nity Employer.PRINCIPAL RESEARCH SCIENTIST for Co-

lumbus area technologs development firm to conductmajor research projects related to the development ofinnovative enzyme immunoassay systems for the measure-ment of a variety of biomolecules including therapeuticdrugs, hormones, infectious agents, cancer markers, andserum proteins; conduct research on immunochcmicaltechniques including antibody production, protein-haptenand enzsme-antibodv conjugations, and proteins purifica-tions by the fast protein liquid chromatography system;write effective research proposals and project reports; trainand direct the work of other project staff. Four years ofexperience required in the job described. In addition, musthave Ph.D. in biochemistry and have taken, as part ofgraduate academic record, at least one course in each oforganic chemistry and enzrme biochemistry. Also, musthave at least two publications in peer-resviewed biochem-istrv journals. Forty hours per week, 8:00 a.m. to 5:00p.m.; $3900 per month. Mrust iaveprotfoflegal authority towork permnanently in the United States. Qualified applicantssend resume in duplicate (no calls) to: S. Holton,JO#1260258, Ohio Bureau of Employment Services,P.O. Box 1618, Columbus, OH 43216.

RESEARCH SCIENTISTIN MOLECULAR BIOLOGY

Virginia-Maryland Regional College of VeterinarnMedicine, University of Marvland College Park, insitesapplications for a faculty research scientist position in fishmolecular virology. Initial appointment will be in theMaryland Agricultural Experiment Station for 3 sears,with likelihood of becoming tenure track. Required:Ph.D. and postdoctoral experience. Submit resume andhave three reference letters sent to: Dr. EdwardStephenson, Search Committee Chair, Regional Col-lege of Veterinary Medicine, University of Maryland,College Park, MD 20742. Application deadline is 15May 1991.The University of Maryland is anl Affitrnative Action/

Equal Opportunity Employer.RESEARCH SCIENTIST. To design small mole-

cule ligands for enzymes and/or receptors implicated in

bone diseases. Plan, supervise, and carry out the enanti-omerically selective synthesis of the targets identified anddevelop new synthetic methodology for the manipula-tion of chiral pool starting materials. Ph.D. in organicchemistry plus 2 years as a research scientist required.Previous experience must include 2 -ears of hands-onexperience designing and synthesis of novel enzyme

ligands as potential therapeutic agents, and developingnovel iodocvclization reactions for the synthesis of bio-logically active compounds. Research experience shouldinclude 2 years hands-on experience in the design andsynthesis of proteinases inhibitors implicated in bonediseases and arthritis. Forts hours per week, Monday to

Friday, 8:00 to 4:30 p.m.; $52,000 per year. Pleaserespond to: Position #INS-MCD3, Rhone-PoulencRorer, 640 Allendale Road, King of Prussia, PA19406. Attention: Human Resources Department.Equal Opportunity Employer, FlM/H/V.

SCIENCEcan publish YOUR LOGO with your one-column lineclassified ad. No extra fee is assessed: you wsill be billed at

our regular line rate for the number of lines the logooccupies. For details, call Classified Advertising: 202-326-6555.

1638

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MAIL TO:Corrine Harris- AAAS/Reprints1333 H Street, NW- Washington, DC 20005

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-DIRECTOR OF LAMPFLos Alamos National Laboratory

Los Alamos National Laboratory, operated by theUniversity of California, is seeking an exceptionalindividual to direct the Los Alamos Meson PhysicsFacility (LAMPF), to lead the Medium EnergyPhysics Division, and to be responsible for theNuclear Physics Program at the Laboratory.

LAMPF is the major national operating nuclearphysics facility, with a large user community. Ithas strong programs in nucleon, pion andelectroweak physics, and provides beams to theLos Alamos Neutron Scattering Center (LANSCE)and the Weapons Neutron Research facility.Candidates must have demonstrated scientificleadership ability, administrative capability, andtechnical experience in the nuclear physics arena.A Ph.D. in physics or equivalent is required.Applications from minority and female candidatesare especially encouraged. To obtain moreinformation or to apply, please contact MollyBirely, MS P282, Personnel Services Division10082-F, Los Alamos National Laboratory, LosAlamos, NM 87545, FAX: (505) 665-2116.

Affirmative Action/Equal Opportunity Employer

Los Alamos-NATIONAL LABORATORY

Benefit FromOur ScientjficAdvancesThe Lindsley F. Kimball Research Instituteof the New York Blood Center is aninternationally recognized research facility,dedicated to both basic and applied researchin the field of hematology and transfusionmedicine. The following opportunities areimmediately available for:

Post-DoctoralPosition

Lab of Virologyand Parasitology

This post-doctoral position is in Molecularand Immunoparasitology. Will involveparticipation in a well-funded project thatcenters on the identification and characteri-zation of putative host protective recombi-nant antigens of the early stages ofOnchocerca volvulus, and the evaluation ofthese antigens as candidates for vaccinedevelopment. Applicants should have aPh.D., M.D. or equivalent with experiencein Molecular Biology and/or Immunology.Salary Mid $20s plus a generous NYChousing allowance offered. For this posi-tion send CV with names and telephonenumber of three references, to: Dr. SaraLustigman, Associate Investigator, Labora-tory of Virology and Parasitology.

Senior ResearchTechnician/

Research AssistantStudy the mechanism of inactivation ofviruses contained in platelet concentratesand other blood cell components. At leastthree years of experience with molecularbiology/virology techniques, including theisolation and analysis of RNA is required.Familiarity with viral nucleic acids, infectivityassays and PCR is desirable, but not essential.For this position send CV to: Dr: HenriettaNunno, Dept of Research & Development.

Send all resumes to:The New York Blood Center

310 East 67th StreetNew York, New York 10021

Ai lindsldy F. KimballResearch InstituteA Division of the New York Blood Center

Where concern for the community comesfirst-

M B A R I

Ocean Science Research PositionsThe Monterey Bay Aquarium Research Institute (MBARI) is seeking scientists interested incarrying out innovative research in the deep ocean. We plan three new positions, two of whichwe expect to till within a year, and the third at a future time. Successful applicants will becomeleaders in establishing vigorous research programs which may be allied with the uniqueopportunity to conduct experiments on the ocean floor, making use of advanced ROVtechnology. There will be opportunity to contribute to the definition and development of the nextgeneration of sensors, samplers, vehicles and systems. The three positions are in thefollowing research fields:Ocean Biology: Experimental studies and/or theoretical analysis of benthic populationsand communities.Ocean Microbiology: Study of microbial processes in the deep ocean and sediments.

Ocean Geochemistry: Organic or inorganic geochemistry of deep ocean bio-geochemical cycles.Positions may be filled at the Assistant, Associate, or Senior Scientist level based uponexperience. Desired qualifications include: Ph.D. in an appropriate scientific field anddemonstrated commitment to a research program in one of the above subject areas. Forappointment at the Associate or Senior level the applicant must have a strong record ofindependent research. Qualified women scientists and minority groups are encouraged to apply.MBARI encourages strong interactions between scientific and engineering research groups forthe development of new ways of carrying out advanced ocean research, and funds are availablefor project initiation. The successful applicant will be encouraged to form collaborative liaisonswith other Monterey Bay Area Research Institutions, including the Monterey Bay Aquarium,Hopkins Marine Station of Stanford University, Moss Landing Marine Laboratories, NavalPostgraduate School, and the University of California at Santa Cruz.Send Curriculum Vitae, a summary of research interests, and the names of four references to,

Search Committee Chair, Monterey Bay Aquarium Research Institute, 160 Central Avenue,Pacific Grove, CA 93950

A

Is S

5z~~~I.1IHybridon, Inc., located in Worcester, MA, is a dy-namic, young pharmaceutical company led by someof the scientific pioneers of antisense technologyHybridon is developing antisenso oligonucleotidedrugs against a variety ofhuman diseases for whichthere is no effective treatment, such as AIDSThe company has new career opportunities currentlyavailable for highly motivated scientists atBS/MS/PhD levels in several areas of "oligonucleo-tide drug" discovery and development.

The successful candidates wi possess a strong syn-

thetic organic chemistry background and a broadknowledge of modem spectral methods andchromatographic techniques. Exposure to the designof new synthetic analogues of nucleosidesioligonucleotides, experience in oligonucleotide syn-thesis scale-up (solid phase or solution phase)and/or oligonucleotide purification procedures wouldbe highly desirable. A BS/MS in Chemistry with atleast one year of laboratory experience is required.Hybridon offers competitive compensation, com-prehensive benefits, a relocation plan and excellentliving conditions in central MA.For confidential consideration, please send yourresume, current salary and the names of threereferences to Dr. Donald E. Kubla:

X)OOCybridon.01 %.AIF %-.W

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POSITIONS OPEN

RESEARCH SCIENTIST. To perform analyticalbiochemical research related to pharmaceutical com-pounds. Develop methods of analytical technology tosupport pharmaceutical analysis in biological matricesusing HPLC, GC/MS, UV/VIS, ECD, Biosensors, infra-red, and nuclear magnetic techniques. Ph.D. in analyticalchemistry plus 2 years of experience performing analyti-cal chemical research required. Previous experience mustinclude 2 years of hands-on experience performing chem-ical research utilizing reverse-phase and ion-exchangeHPLC with electrochemical UV/VIS and fluorescencedetections, ECD, and IR including development andmodification of ECD construction of biosensors andsynthesis of HPLC column packing materials. Fortyhours per week, Monday to Friday, 8:15 a.m. to 4:45p.m.; $48,000 per year. Please respond to: Position#INS-DM2, Rhone-Poulenc Rorer Central Re-search, 640 Allendale Road, King of Prussia, PA19406. Attention: Human Resources Department.Equal Opportunity Employer, F/M/H/V.

RESEARCH SCIENTIST. To design and developexperimental models to study cellular interactions inimmune responses, particularly in inflammatory reac-tions. To direct research aimed at development of poly-clonal and monoclonal antibodies to cell surface recep-tors involved in leukocyte activation and adhesiveinteractions and purification of the receptors and explo-ration of their structure and function, and identificationof potential inhibitors of leukocyte activation, adhesion,and migration in inflammatory diseases. Ph.D. in cellularimmunology plus 1 year's experience as research scientist/immunology required. Previous experience must include1 year's hands-on experience cloning leukocyte adhesionprotein genes, and performing molecular analysis ofleukocyte adhesion deficiencies, and research in structureand function of phosphatidylinosiel-anchored proteinsinvolved in immune responses. Forty hours per week,Monday to Friday, 8:30 a.m. to 4:30 p.m.; $52,000.00per year. Please respond to: Position #INS-ID1,Rhone-Poulenc Rorer Central Research, 640 Allen-dale Road, King of Prussia, PA 19406. Equal Oppor-tunity Employer, M/F/H/V.

ASSISTANT RESEARCH SCIENTIST. Dutiesinclude: independent design and performance of experi-ments in microvascular physiology; the responsibility fordeveloping a new, unique approach to study water andsolute transport in isolated coronary venules 20 to 50 gmin diameter; the use of surgical skills to dissect, isolate,and cannulate the vessels; and the independent capabilityto plan experiments, conduct the studies, and writereports on the results. Salary: $2083.33 per month, 40hours per week. Requires M.D., Ph.D., or equivalent inmedical studies, and 2 years of related experience inresearch in microvascular physiology. Apply at: TheTexas Employment Commission, Bryan, Texas, orsend resume to: The Texas Employment Commission,TEC Building, Austin, TX 78778, Job Order#5757260. Ad paid by an Equal Employment OpportunityEmployer.

ANNOUNCEMENTS

RESEARCH GRANTS AND FELLOWSHIPSThe American Epilepsy Society and the Epilepsy

Foundation of America offer research grants and fellow-ships. For applications and guidelines write:

Epilepsy Foundation of AmericaResearch Administration4351 Garden City DriveLandover, MD 20785

Telephone: 301-459-3700

RESEARCH INQUIRIES INVITED

The Smokeless Tobacco Research Council, Inc., in-vites inquiries regarding grant applications.The council sponsors independent research into ques-

tions of smokeless tobacco and health. Research supportis through a program of grants-in-aid.

Grant applications are evaluated by the Scientific Ad-visory Board to the council and will be judged solely onthe basis of scientific merit and relevance.

Deadlines for submission of grant applications are 31December for 1 July funding and 30 June for 1 Januaryfunding. Address inquiries or requests for applicationsto: The Smokeless Tobacco Research Council, Inc.,420 Lexington Avenue, New York, NY 10170. Tele-phone: 212-697-3485.

COURSES AND TRAINING

PREDOCTORALINTERDISCIPLINARY PROGRAM

CELL STRUCTURE AND FUNCTIONIN HEALTH AND DISEASE

The University of Florida has initiated a new programproviding well-qualified graduate students with a broadspectrum of research opportunities in cell structure andfunction tailored to the specific needs of each student.Faculty interests are diverse and include developmentaland regulatory biology, intracellular targeting, cytoskel-eton, signal transduction, immunobiology, cancer biolo-gy, and the mechanism ofviral infection. The student willreceive a Ph.D. degree jointly through a basic sciencesdepartment and the Interdisciplinary Program. Compet-itive stipends are offered by the program. For furtherinformation contact: Dr. Carl Feldherr, Department ofAnatomy and Cell Biology, College of Medicine,University of Florida, Gainesville, FL 32610-0235.

FUNDAMENTAL NEUROBIOLOGICALAPPROACHES TO DISEASE:

BRAIN MECHANISMSIN NEUROPSYCHOLOGY

19 TO 24 MAY 1991The Neurosciences Institute will sponsor an intensive,

week-long course emphasizing the disease process as an

object for biological research. The purpose is to intro-duce scientists to the basic physiology and pathology ofselected human syndromes affecting behavior and to theopportunities they provide for solving fundamental bio-logical problems.The course program will review both clinical phenom-

ena and pertinent areas of basic neuroscience in a formatthat includes lectures, clinical case presentations, andsmall group discussions. Instructors will include UrsulaBellugi, Hans-Joachim Freund, Joachim Fuster, PatriciaGoldman-Rakic, Charles Marsden, Marek Marsel Mesu-lam, Mortimer Mishkin, Fred Plum, Michael Posner,Marcus Raichle, Vilayanur S. Ramachandran, LarrySquire, Thomas Thach, Larry Weiskrantz, RobertWurtz, and Semir Zeki.

Applications are invited from scientists with advancedtraining and experience in neuroscience or related bio-logical sciences. Participants' expenses will be reimbursedby the institute.For application forms or further information, please

write to: Dr. W. Einar Gail, Research Director, TheNeurosciences Institute, 1230 York Avenue, NewYork, NY 10021 or telephone: 212-570-8975.

CAREER CHANGE OPPORTUNITYThis unique program offers the candidate with an

earned doctorate in the sciences the opportunity toobtain the Doctor of Optometry (O.D.) degree in twocalendar years. Employment opportunities exist in pri-vate practice, industry, education, and research. Contact:Dr. D. Chauncey, Program Director, AcceleratedProgram, The New England College of Optometry,Room S 424 Beacon Street, Boston, MA 02115.

SCIENCE recruitment ads reach thousands of scien-tists in all disciplines, worldwide. Classified Advertisingtelephone: 202-326-6555. FAX: 202-682-0816.

MARKETPLACE

Circle No. 222 on Readers' Service Card

lu~vu a unas gto mae *|rs l gounases ioi.uiovrueach additional base. No additional charges.

Research GeneticsNU,

Circle No. 267 on Readers' Service CardSCIENCE, VOL. 251

HEIThe Health Effects InstituteEighth Annual Conference

April 21-24, 1991Colorado Springs, Colorado

The purpose of this meeting is to foster com-munication among scientists, governmentofficials, and motor vehicle industry represen-tatives. The program includes lectures by inter-nationally recognized speakers, poster sessionswith HEI investigators, and a workshop onexperimental exposure to reactive gases.Individual sessions will address: HumanExposure Assessment; Assessing HumanHealth Risk from Animal Chronic BioassayData; and Disease Causation: IntegratingHuman and Laboratory Animal Data forBenzene and for 1,3-Butadiene.The Health Effects Institute is a non-profitcorporation that supports studies to evaluatehealth effects of automotive emissions. It isfunded jointly by the U.S. EnvironmentalProtection Agency (EPA) and the automotiveindustry. Current research is investigating thehealth effects of a wide variety of pollutants,including methanol, nitrogen oxides, ozone,and diesel emissions.

Registration for the meeting is $125. Participa-tion is limited and by pre-registration only.For further information contact:

The Health Effects Institute141 Portland Street, Suite 7300

Cambridge, MA 02139(617) 621-0266

SUBSTRATE TABLETSELISA

WESTERN BLOTHISTOCHEMISTRY

OPDDABTNBAECFAST RED

BioTrek, Inc.(405) 720-9203 I

NATIONAL INSTITUTES OF HEALTH

CELLULAR AND MOLECULARBIOLOGIST IN

VASCULAR-IMMUNE SYSTEMSAND HIV-1 GENE REGULATION

The Laboratory of Tumor Cell Biology of theDivision of Cancer Etiology, National CancerInstitute is accepting applications for a permanentposition for a medical doctor with researchexperience. The position has a salary range of$54,694 - $67,996.

The successful candidate will be expected to:

1. Conduct original research in the area of AIDS-associated malignancies (Kaposi's Sarcoma andB cell lymphoma) and HIV-1 gene regulation withemphasis on the investigation of the mechanismof action of HIV-1 regulatory gene products andcytokines on vascular cells and immune cells,using techniques of cellular and molecularbiology.

2. Serve as Project Officer for extramural contract(s)to test the effectiveness of the use of antisensecompounds in blocking the action of HIV-1regulatory genes and cytokine genes.

3. Provide expert consultation to the Program in mat-ters involving the study of AIDS-associatedKaposi's sarcoma, B cell lymphoma and HIV-1regulatory genes.

Candidates with the following qualifications willbe given preference:

1. M.D. (M.D. and Ph.D. are preferred) with back-ground in immunology or other subject wheretraining was focused on AIDS and AIDS-relatedmalignancies.

2. Postdoctoral research experience in HIV-1 generegulation and the interaction of cytokines withvascular and immune systems.

3. Strong interest in developing a research programwhich utilizes techniques of cellular andmolecular biology to impact the areas of the roleof retroviruses, particularly HIV-1, in thepathogenesis of tumors.

4. Broad knowledge of HIV-1 gene function and reg-ulation, cytokines and their regulation, AIDS andKaposi's sarcoma.

5. Ability to communicate effectively both orally andin writing.

6. Relevant publications in related scientific journals.

Applicant must be found to be eligible on a CivilService Register. If interested, please send acurriculum vitae by April 15, 1991 to:

Ms. Patricia Stephenson, AO, BCPNational Institutes of Health LBuilding 37, Room 1A079000 Rockville PikeBethesda, MD 20892 cp

U.S. Citizenship RequiredNIH is an Equal Opportunity Employer

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What began as alocal breweryhas grown intoan internationalcompany. If you'dlike to share theexcitement of working fora Fortune 50 companywith a century oldtradition of quality,we have an opening /for you.

YeastPhysiologistResponsibilities for this position includeinitiating and executing programs tooptimize yeast performance in beer fer-mentations. These programs will encom-pass determining the effect of raw materialsand process variables on beer fermenta-tions and establishing the relationshipbetween karotype and yeast performance.The ideal candidate must have a Ph.D. inmicrobiology or biochemistry with a mini-mum of 2 years' postdoctoral or industrialexperience. Previous research involvingyeast physiology and genetics is required.If you're a goal-oriented, team player ableto share your knowledge with various de-partments and disciplines, we're preparedto reward your efforts with an attractivesalary and benefits. For consideration,please send your resume with salary his-

tory to: ANHNUSER-BUSCHCOMPANIES; Corporate_ iployment; Dept A61-KB.

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Opportunity Employer M/F.

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