biotechnology: industry report ,march 2013
DESCRIPTION
The Indian biotechnology sector is one of the fastest growing knowledge-based sectors in India and is expected to play a key role in shaping India's rapidly developing economy. With numerous comparative advantages in terms of research and development (R&D) facilities, knowledge, skills, and cost effectiveness, the biotechnology industry in India has immense potential to emerge as a global key player.The Indian biotech industry registered 18.5 per cent growth in FY12; total industry size stood at US$ 4.3 billion by the end of the financial year. The industry is expected to increase in size to US$ 11.6 billion by 2017, driven by a range of factors including growing demand, intensive R&D activities and strong Government initiatives.This exceptional growth has been facilitated by the robust performance of all the sub-sectors of the Indian biotechnology industry, namely, bio-pharmaceuticals, bio-services, agri-biotech, bio-industrial, and bio-informatics. Bio-pharmaceuticals is the largest sub-sector of the industry, whereas agri-biotech is the fastest growing. Out of the top 10 biotech companies in India (by revenue), six specialise in bio-pharmaceuticals and four specialise in agri-biotech.TRANSCRIPT
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Contents Advantage India Market overview and trends Growth drivers Success stories: Biocon Opportunities Useful information
For updated information, please visit www.ibef.org
Biotechnology
MARCH2013
33
Biotechnology
For updated information, please visit www.ibef.org ADVANTAGE INDIA
Advantage India
MARCH2013
Advantage
India
• India’s billion-plus population base offers a huge market for biotech products and services
• Increasing economic prosperity and health consciousness will continue to fuel demand for healthcare services
• Public funding for product innovation and research in the biotech sector
• The private sector has been aggressive in pursuing focused R&D
• FDI investment up to 100 per cent is permitted via the automatic route
• A low cost and skilled labour force is attracting outsourced research activity
• The sector has experienced significant growth in government spending since 1985
• Increasing budgetary allocations to the biotech sector
• Setting up of Biotechnology Industry Research Assistance Council
Market size:
USD11.6 billion
FY17F
Market size:
USD4.3 billion
FY12
Source: Association of Biotechnology Led Enterprises (ABLE) June 2012, Global Industry Analysts report (GIA), Aranca Research
Notes: 2017F - Forecast for 2017
Demand potential
Innovation opportunities
Increasing investments Policy support
44
Contents Advantage India Market overview and trends Growth drivers Success stories: Biocon Opportunities Useful information
For updated information, please visit www.ibef.org
Biotechnology
MARCH2013
55For updated information, please visit www.ibef.org MARKET OVERVIEW AND TRENDS
Major milestones in Indian biotechnology industry
Biotechnology
• 1978: India’s first biotech firm, Biocon, was setup
• 1981: Centre for Cellular and Molecular Biology was setup in Hyderabad
• 1984: Institute for Microbial Technology, Chandigarh was setup
• 1986: Department of Biotechnology (DBT) was formed
• 1987: National Institute of Immunology was setup by DBT
• 1989: Bangalore Genei commenced operations
• 1991: National Centre for Biological Sciences pursues R&D in molecular biology
• 1994: Syngene, India’s first Contract Research Organisation(CRO), starts its R&D services
• 1997: Centre for Biological Technology (CBT) was established to focus on bioinformatics and genomics
• 1998: Monsanto Research established an R&D centre for plant genomics
• 1998: DBT approves Mahyco-Monsanto to grow Bt cotton
• 2001: The drug authority implements Good Clinical Practice (GCP) guidelines for clinical trials
• 2002: Genetic Engineering Approval Committee (GEAC) approves Bt cotton for commercial planting
• 2007: National Biotechnology Development Strategy launched
• 2009: National Biotechnology Regulatory Authority Bill 2008 to be introduced in parliament
• 2011: Government approved setting up of Biotechnology Industry Research Assistance Council (BIRAC)
1978-1990 1990-1999 Post 2000
Source: EXIM bank of India research, Aranca ResearchNotes: R&D - Research and Development
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66For updated information, please visit www.ibef.org
Key segments in the Indian biotechnology industry
Source: ABLE - Biospectrum industry survey, June 2012; Aranca Research
MARKET OVERVIEW AND TRENDS
Biotechnology
Bio-pharmaceutical products are therapeutic or preventativemedicines that are derived frommaterials naturally present in livingorganisms, using recombinant DNA(rDNA) technology
Bio-services mainly include clinicalresearch and CRO along with custom manufacturing
Bio-agriculture is segmented into hybrid seeds, transgenic crops, bio-pesticides and bio-fertilizers
Bio-industrial predominantly comprises enzymemanufacturing and marketing companies
Bio-informatics deals with the creation and maintenance ofextensive electronic databases on various biological systems; it is the smallest part of the current domestic biotechnology industry
Bio-pharma Bio-services Bio-agri Bio-industrial Bio-informatics
Biotechnology
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77For updated information, please visit www.ibef.org
Major products/services of the Indian biotechnology industry
MARKET OVERVIEW AND TRENDS
Sources: ABLE - Biospectrum Industry Survey, June 2012; Aranca Research
Biotechnology
Biotechnology
Bio-pharma Bio-services Bio-agri Bio-industrial Bio-informatics
Vaccines
Diagnostic
Therapeutic
Custom Manufacturin
g
CRO Hybrid seeds
Bio-fertilizers
Bio-pesticides
Industrial enzymes
Database services
Integrated research app
softwareBiotech software services
MARCH2013
88For updated information, please visit www.ibef.org MARKET OVERVIEW AND TRENDS
→ Keeping on with the growth momentum of the previous years, the Indian biotech industry registered 18.5 per cent growth in FY12; total industry size stood at USD4.3 billion by the end of the financial year
→ Fast-paced growth is likely to continue; the industry is expected to increased in size to USD11.6 billion by 2017, driven by a range of factors including growing demand, intensive R&D activities and strong government initiatives
Market size over the past few years in USD billion
Source: ABLE - Biospectrum industry survey, June 2012, Aranca Research
Notes: CAGR - Compound Annual Growth Rate
Biotechnology
Source: Global Industry Analysts report (GIA)
FY05 FY06 FY07 FY08 FY09 FY10 FY11 FY120.0
1.0
2.0
3.0
4.0
5.0
1.01.4
1.82.1
2.53.0
3.6
4.3
CAGR23.2 %
MARCH2013
Robust growth in the biotech industry
99For updated information, please visit www.ibef.org MARKET OVERVIEW AND TRENDS
→ The bio-pharmaceutical sector accounted for the largest chunk of the biotech industry, with a share of 62.0 per cent in total revenues in FY12
→ In the same year, bio-services and the bio-agri segments followed the bio-pharmaceutical segment with shares of 18.3 per cent and 14.9 per cent respectively
→ Growth was fastest in the bio-agri segment (23.0 per cent in FY12), followed by bio-pharma (19.0 per cent) and bio-services (15.5 per cent)
Market break-up by revenues (FY12)
Source: ABLE - Biospectrum industry survey, June 2012, Aranca Research
Bio-pharma accounts for a major share of the market; fastest growth in FY12 by bio-agri
Biotechnology
62.0%
18.3%
14.9%
3.4%1.3%
Bio-pharma
Bio-services
Bio-agri
Bio-industrial
Bio-informatics
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1010For updated information, please visit www.ibef.org
Growth was driven by both domestic and export markets … (1/2)
MARKET OVERVIEW AND TRENDS
→ Domestic bio-services sector grew an astounding 102 per cent in FY12 to USD109.3 million
→ The domestic bio-pharma sector, which accounts for more than 61 per cent of the domestic biotech industry, registered a 26.6 per cent growth in FY12; in comparison growth in domestic bio-informatics sector was 24 per cent
Domestic business growth of biotech industry (FY12)
Source: ABLE - Biospectrum industry survey, June 2012, Aranca Research
Biotechnology
Bio-services Bio-Pharma Bio-Informat -ics
Bio-agri Bio-industrial0%
20%
40%
60%
80%
100%
120%
101.9%
26.6% 24.0% 20.4%
11.1%
MARCH2013
1111For updated information, please visit www.ibef.org MARKET OVERVIEW AND TRENDS
→ Bio-pharma export revenues contribute more than 63 per cent to total export revenues of the biotech sector; the segment registered a growth of 12.2 per cent in FY12 to touch USD1.3 billion
→ Most impressive was the growth in bio-agri sector export revenues which more than doubled in FY12 to USD31.9 million; this yet again points to the export potential in the segment and one that the industry looks set to exploit in the coming years
Export business growth of biotech industry (FY12)
Source: ABLE - Biospectrum industry survey, June 2012, Aranca Research
Biotechnology
Bio-agri Bio-pharma Bio-industrial Bio-services Bio-informat -ics
-30%
0%
30%
60%
90%
120%106.8%
12.2% 11.3% 8.0%
-19.8%
MARCH2013
Growth was driven by both domestic and export markets … (2/2)
1212For updated information, please visit www.ibef.org
Bio-pharma leads the export earning business
MARKET OVERVIEW AND TRENDS
→ Biotech export revenue reached USD2.1 billion in FY12, nearly half (48 per cent)of total industry revenue
→ Over the years export revenue has growth considerably from USD0.4 billion in FY05 to USD2.1 billion in FY12 (a CAGR of 25.6 per cent)
Exports of biotechnology products (FY12) (USD billion)
Source: ABLE - Biospectrum industry survey, June 2012, Aranca Research
Biotechnology
Export share among major sub sectors (FY12)
Source: ABLE - Biospectrum industry survey, June 2012, Aranca Research
63.1%
32.8%
1.6% 1.7%0.9%
Bio-pharma
Bio-services
Bio-agri
Bio-industrial
Bio-informatics
FY05 FY06 FY07 FY08 FY09 FY10 FY11 FY120.0
0.5
1.0
1.5
2.0
2.5
0.4
0.7
1.01.2
1.5 1.6
1.82.1CAGR
25.6 %
MARCH2013
1313For updated information, please visit www.ibef.org MARKET OVERVIEW AND TRENDS
Source: ABLE - Biospectrum industry survey, June 2012,Aranca Research
Notes: * - Estimates
The Indian biotech industry is fairly competitive
Biotechnology
Top 10 players in the Indian biotech industry
CompanyRevenue (USD million) FY12
CompanyRevenue (USD million)
FY12
Serum Institute of India 355.8 Rasi seeds 81.7
Biocon 349.3 Panacea Biotec* 80.0
Nuziveedu Seeds 155.2 Bharat Biotech 67.9
Reliance Life sciences* 144.4 Ankur Seeds 67.7
NovoNordisk * 134.9 Mahyco 65.4
Top 20 companies accounted for 76.1 per cent of industry revenues in FY12
MARCH2013
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Source: Aranca Research, Indian Law Offices
Notable trends in the Indian biotech sector
Biotechnology
Remarkable global positioning
Pharma companies are
focusing on biotech
• Ranbaxy, Cadila Healthcare, Lupin, Wockhardt and Dr Reddy’s are among the major Indian pharmaceutical companies that operate in the bio-pharma segment
Global companies setting up base
• Lonza, the global leader in the production and support of pharmaceutical and biotech products, is planning to set up a manufacturing base in India at an investment of USD150 million in Hyderabad. The investment outlay has been planned over two phases:
• Phase I (from 2011 to 2013) would include the development of R&D labs for more than 100 resources
• Phase II (from 2014 to 2015) would include the expansion of manufacturing capabilities and the provision for increasing R&D lab capacity for biologics with 200 additional resources
• India is amongst the top 12 biotech destinations in the world• India ranks second in Asia, after China• India is the largest producer of recombinant Hepatitis B vaccine in the
world
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Contents Advantage India Market overview and trends Growth drivers Success stories: Biocon Opportunities Useful information
For updated information, please visit www.ibef.org
Biotechnology
MARCH2013
1616For updated information, please visit www.ibef.org GROWTH DRIVERS
Sector benefits from both rising income and population
Biotechnology
Strong government
support
Large domestic market
Growing demand
Inviting Resulting in
Growing demand Increasing investments Policy support
India’s large population is a
huge market for biotech products
and services
Increased healthcare
expenditure due to rising income
Strong growth in export demand
Significant growth in government spending on
biotech sector since 1985
R&D focus; Indian government has
been funding institutes for
biotech research
Increasing budgetary
allocation to the Department of
Biotechnology in five- year plans
Rising investments from domestic and
foreign players
100 per cent FDI is permitted through automatic route for manufacturers of
drugs and pharmaceuticals
A low cost and skilled labour force
is attracting outsourced research
activity
Source: Aranca Research
MARCH2013
1717For updated information, please visit www.ibef.org
Source: Mid term appraisal," Eleventh Five Year Plan, National Biotechnology development strategy, DBT,
Aranca ResearchNotes: FYP - Five Year Plan
Increased healthcare expenditure driving domestic demand
GROWTH DRIVERS
Biotechnology
Exponential growth in government funding• Healthcare expenditure, as a percentage of GDP, for
the 11th Five Year Plan was around 5.0 per cent• Government expenditure on healthcare as a
percentage of total expenditure on health in the country was 29.2 per cent in 2010
• During 2007-10, the percentage of allocated resources utilised by DBT was 94.5 per cent
Preventive healthcare
• Around 1.2 billion ailments are reported annually, and this number is expected to rise by at a CAGR of 30 per cent to reach 15 billion cases by 2015. Better access to healthcare facilities and rising lifestyle diseases are driving this trend
• Population growth have elevated the vaccine demand for the geriatric and paediatric population
Specialised treatment
• The disease profile that inflicts the Indian population has experienced a gradual shift. The number of lifestyle-related diseases being reported is rising; this has led to demand for various kinds of specialised treatments
• Ailments such as cancer and diabetes have boosted demand for biological products
Source: WHO Statistics 2012
Ninth FYP Tenth FYP Eleventh FYP Twelfth FYP
129 302
1,354
3,726Funds availability (USD million)
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1818For updated information, please visit www.ibef.org
Source: Fortis Healthcare Limited 2008-09 ANR
Rising income and incidence of chronic diseases
GROWTH DRIVERS
Biotechnology
Rising incomes; growing middle class• Growing per-capita incomes; rural incomes also rising
• Expanding middle class population; this segment’s size is estimated to touch 550 million by 2025 from 50 million in 2010
• Rising per capita income leads to increased spending on medical and healthcare services
Higher incidence of chronic diseases• Lifestyle diseases are set to account for a greater part
of the healthcare market
• Lifestyle diseases such as cardiac diseases, cancer and diabetes are treated with the help of biotechnology products, thereby boosting revenues of biotech companies
Notes: Greater distributional efficiencies, increasing demand (especially from rural areas) due to rising disposable
incomes have created new markets for products within the country
22%
78%
2001
Acute in-fections
Lifestyle & Others
14%
86%
2012F
2005 2010 2015 2020 20250
10
20
30
40
50
60
70
Strivers Seekers DeprivedAspirers Globals
Source: McKinsey Quarterly, Aranca Research
Aspirers: annual income
INR90,000 -200,000
million households Seekers: annual income INR200,000 -
500,000
Deprived annual income
<INR90,000
Globals: annual income
>INR1,000,000
Strivers: annual income INR500,000 -
1,000,000
MARCH2013
1919For updated information, please visit www.ibef.org
Strong policy support is crucial to the sector’s development
GROWTH DRIVERS
Biotechnology
Source: “Biotechnology facilities,” Department of Biotechnology, Aranca Research
Note: BIRAC - Biotechnology Industry Research Assistance Council
• As per NBDS, a proposal has been made to set up National Biotechnology Regulatory Authority (NBRA) to provide a single-window clearance mechanism for all bio-safety clearances of products to create efficiencies and streamline the drug approval process
New facilities
National Biotechnology Development
Strategy
• DBT designed National Biotechnology Development Strategy (NBDS) to strengthen the industry’s human resources and infrastructure while promoting growth and trade
• As part of the NBDS, government has decided to spend 30 per cent of DBT’s budget in public private partnerships to promote Research & Development at various stages
Single-window clearance
• DBT set up 35 facilities during 2002-07 to produce and supply biological products, reagents, culture collections and laboratory animals to scientists, industries and students at nominal costs
• The government launched a biotechnology industry partnership programme for developing new technologies
Biotechnology Industry Research Assistance Council
• BIRAC has been established to promote research and innovation capabilities in India’s biotech industry
• Under BIRAC, the government will provide funding to biotech companies for technology and product development
MARCH2013
2020For updated information, please visit www.ibef.org
Government funding is crucial for the biotech industry
GROWTH DRIVERS
Biotechnology
Source: Ernst & Young, Aranca Research
Venture fund
Infrastructure development
• India’s central government and the state governments in collaboration with private players continue to develop new infrastructure facilities, especially through biotechnology parks
• Government is developing three major biotech clusters at Mohali in Punjab, Faridabad in Haryana, Bengaluru in Karnataka.
International collaborations
• International collaborations with different countries are directed at enabling the effective transition of knowledge
• India has partnered with countries such as the UK, Russia, Italy, the US and France to enable knowledge transition
• The government announced a plan to set up a USD2.2 billion venture fund for supporting drug discovery and research infrastructure development projects
• Government funding is crucial for the biotech industry as they have limited access to other sources of funding
Clinical Establishments Bill
• In a move to standardise procedures, the Indian Parliament passed the Clinical Establishments Bill 2010, which would make registration of clinical trials as well as clinical research organisations mandatory in the country
• The bill also includes standard operating procedures for various trial related tasks
MARCH2013
2121For updated information, please visit www.ibef.org
Centre and state government initiatives have provided big boost to biotech industry
GROWTH DRIVERS
Biotechnology
Source: Ernst & Young, Aranca ResearchNote: BIPP - Biotechnology Industry Partnership Programmes, SBIRI - Small Business Innovation
Research Industry, BIRAC - Biotechnology Industry Research Assistance Council,
IP - Intellectual Property
Increasing Government Support
100 per cent foreign equity investment is possible in manufacturing of all drugs except recombinant DNA products and cell targeted therapiesSingle window processing mechanism for all biotech projects involving FDIDepreciation allowance on plant and machinery has been raised to 40 per cent from 25 per centCustoms duty exemption on goods imported in certain cases for R&D
Customs & excise duty exemption to recognised Scientific & Industrial Research Organisations (SIRO)
150 per cent weighted tax deduction on R&D expenditure
3 years excise duty waiver on patented products
Products100 per cent rebate on own R&D expenditure125 per cent rebate if research is contracted in public funded R&D institutionsJoint R&D projects are provided with special fiscal benefitsSetting up a venture capital fund to support small and medium enterprisesPromoting innovations through: BIPP, SBIRI, BIRAC and Biotech parks
Favorable IP ClimateIndian Copyright Act, 1957 The Patent Act, 1970Indian Patents and Design Act, 1972 The Trademarks Act, 1999 Biotechnology Patent Facilitating Cell (BPFC)Foundation of Biotechnology Awareness and Education (FBAE)National Research Development Corporation (NRDC)
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Source: Policy and rules,” Department of Biotechnology website, Aranca Research
Regulatory framework of the Indian Biotech Sector
GROWTH DRIVERS
Biotechnology
Government of India
Ministry of Science & Technology
Ministry of Environment &
Forests
Department of Biotechnology
Department of Environment,
Forests & Wildlife
Recombinant DNA Advisory Committee
(RDAC)
Regulatory Committee on
Genetic Manipulation
(RCGM)
Institutional Biosafety
Committee (IBSC)
Genetic Engineering
Approval Committee
(GEAC)
MARCH2013
2323For updated information, please visit www.ibef.org
→ The 12th Five Year Plan aims to set up 3-5 bio-clusters with technology incubators, technology parks, innovation centers and entrepreneurship development units
→ Biotechnology infrastructure is witnessing a shift from traditional clusters to specialised industrial infrastructure such as biotech or science parks
→ States such as Andhra Pradesh, Maharashtra, Tamil Nadu and Kerala have been early movers in establishing world-class biotech parks and clusters
→ Investors such as TCG Bio-pharma and Alexandria have significantly contributed to the establishment of biotechnology-related infrastructure in India
Source: Planning Commission, Aranca Research, "Mid term appraisal," Eleventh Five Year Plan
Solid industry infrastructure would drive growth
GROWTH DRIVERS
Biotechnology
JogindernagarShimla
Chandigarh
AlwarSohnaJodhpur Jaipur
Gandhinagar AnandJamnagarBaroda
AurangabadPune
Hyderabad
BhubaneshwarKonark
Midnapore
Pantnagar
BengaluruChennai
Puducherry
Visakhapatnam
Kochi
Karwar
Madurai
Operational biotech parks
MARCH2013
2424For updated information, please visit www.ibef.org
Source: MISSOURI, International Trade and Investment Office - India bio 2012, Aranca
Research
Karnataka: The biotech capital of India
GROWTH DRIVERS
Biotechnology
19%
17%
10%26%
8%
8%
13% Bangalore
Hyderabad
Pune
Mumbai
NCR
Ahmedabad
Others
Top biotech clusters in India - 2011→ 60 per cent of biotech companies in India have a base in Bengaluru
→ 50 per cent of total revenues in the national biotechnology sector comes from Bengaluru
→ Extensive intellectual capital→ 12 biotechnology finishing schools under
Millennium Biotech Policy II→ 103 R&D centers
→ Extensive industrial infrastructure→ Sector focused SEZs: Mysore, Mangalore, Hubli -
Dharwar, Belgaum, Shimoga, Gulbarga, Kolar and Mandya
→ 86 acre biotechnology park - Bangalore Helix with 52 acre Alexandria Knowledge Park in Bengaluru
→ Pro industry policy: State Millennium Biotech Policy II 2010, State Industrial Policy 2009-14
→ K-Bio Venture Capital Fund of USD10.4 million with 26 per cent stake by Government of Karnataka
→ Financial support of 20 per cent of the project cost for PPP-based projects for creation of biotech parks
MARCH2013
2525For updated information, please visit www.ibef.org
→ During the 11th Five Year Plan, the government started six new institutions in different fields of biotechnology across India
→ Fellowships rose from 100 to 250 per year for PhD students in addition to 100 postdoctoral and 50 biotechnology overseas associateships
→ Government provide grant-in-aid to the industry for R&D in certain diseases such as malaria and leishmaniasis or kala-azar
High-end research infrastructure creates scope for innovation
GROWTH DRIVERS
Biotechnology
Details of key biotechnology parks in IndiaParks City Area (in
acres)Shapoorji Pallonji Biotech Park Hyderabad 300
ICICI Knowledge Park Hyderabad 200International Biotech Park Pune 103
Lucknow Biotech Park Lucknow 20Golden Jubilee Biotech Park Chennai 8
Ticel Bio Park Chennai 5
Key research institutes in IndiaCentral Drug Research Institute (CDRI), LucknowNational Institute of Pharmaceutical Education and Research (NIPER), MohaliIndian Institute of Chemical Technology (IICT), HyderabadCentre for Cellular & Molecular Biology (CCMB), HyderabadIndian Institute of Chemical Biology (IICB), KolkataIndian Toxicology Research Institute (ITRI), LucknowInstitute of Genomics and Integrative Biology (IGIB), New DelhiInstitute of Microbial Technology (IMTECH), ChandigarhNational Chemical Laboratory (NCL), PuneNational Centre for Biological Sciences (NCBS), BengaluruJawaharlal Nehru Centre for Advanced Scientific Research (JNCASR), BengaluruIndian Institute of Science (IISc), BengaluruNational Institute of Immunology (NII), New Delhi
Source: Aranca Research, "Mid term appraisal," Eleventh Five Year Plan
MARCH2013
2626For updated information, please visit www.ibef.org
→ From November 2000 to August 2010, the drugs and pharmaceuticals sector attracted foreign direct investment (FDI) worth USD1.8 billion
Strong inflows of foreign investment
GROWTH DRIVERS
Biotechnology
Source: Thomson One Banker, Aranca analysisNote: * - Estimated value
Date Announced Acquirer Name Target Name Value of Deal(USD million)
Nov 2012 Bristol-Myres squibb Biocon’s (IN-105) oral insulin 300-350*
Jul 2012 Serum Institute of India Ltd NVI - Vaccin Production Unit 40.28
Jun 2012 Nandan Cleantec PLC Xtraa Cleancities Infra -
Mar 2012 Investor Group Titan Biotech Ltd -
Jan 2012 Xenetic Biosciences plc Symbiotec Pharmalab Ltd 9.34
Jan 2011 Evolvence India Life Sciences Fermenta Biotech Ltd 8.90
Jul 2010 Marck Biosciences Ltd Ravish Infusions Ltd 1.22
Jun 2010 Piramal Healthcare Ltd BioSyntech Inc 4.20
May 2010 Sequoia Capital India Invest Celon Laboratories Ltd 15.74
Apr 2010 Anu's Laboratories Ltd Stilbene Chemicals Ltd -
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Contents Advantage India Market overview and trends Growth drivers Success stories: Biocon Opportunities Useful information
For updated information, please visit www.ibef.org
Biotechnology
MARCH2013
2828For updated information, please visit www.ibef.org SUCCESS STORIES: BIOCON
Biocon: An early mover to the global biotech market
Biocon’s position in the Indian market during FY12
Ranked 1st among Indian Insulin companies
Ranked 1st in the Glargine vial market
Ranked 3rd in the 40 IU Insulin market
Ranked 4th in overall Insulin market
Biotechnology
• Incorporated in 1978 at Bengaluru, India
• IPO offering in 2004 (BSE, NSE India)
• Among the world’s largest producers of statins and immuno -suppressants
• 2011: Launched INSUPen®, a convenient and affordable reusable insulin delivery device
• Market cap of USD1.2 billion
• Revenue reported in H1FY13 was USD257.3 million (up 23 per cent YoY) while net profit was USD35.08 million
Source: Biocon Fact Sheet
FY08 FY09 FY10 FY11 FY12 H1FY13
227249
311
387448
257
47 49 56 7171
35
Revenue (USD million) Net Profit (USD million)
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Contents Advantage India Market overview and trends Growth drivers Success stories: Biocon Opportunities Useful information
For updated information, please visit www.ibef.org
Biotechnology
MARCH2013
3030For updated information, please visit www.ibef.org
Source: India Law Offices, Aranca Research
Huge opportunities for innovation in agriculture/healthcare
Biotechnology
• India has the potential to become a major producer of transgenic rice and several genetically modified (GM) or engineered vegetables
• Hybrid seeds, including GM seeds, represent new business opportunities in India based on yield improvement
Vaccines
Bioactive therapeutic proteins
• Protein and antibody production and the fabrication of diagnostic protein chips is a promising area for investment
• Stem cell research, cell engineering and cell-based therapeutics is another area, wherein India will cash in its expertise
Agriculture sector
• Vaccines and recombinant therapeutics are the leading sectors driving the biotechnology industry’s growth in India
• Newer therapies are anticipated to launch in the next few years, prominent among these are monoclonal antibodies products, stem cell therapies and growth factors
• The country’s huge population places it among the world’s largest markets for vaccines
OPPORTUNITIES
MARCH2013
3131For updated information, please visit www.ibef.orgSource: India Law Offices, Aranca Research
Outsourcing opens up further avenues of growth for biotech
Biotechnology
• Indian bioinformatics companies can play a significant role in critical areas such as data mining, mapping and DNA sequencing
• There is also opportunity in functional genomics, proteonics and molecule design simulation
Contract research
Clinical trials and outsourcing
• India offers a suitable population for clinical trials because of its diverse gene pools, which cover a large number of diseases
• Cost effectiveness, competition, and increased confidence on capabilities and skill sets have propelled many global pharmaceutical companies to expand their own clinical research investment in the nation
Bio informatics
• The R&D sector has huge potential; many opportunities have been created with a number of foreign companies investing in this sector
• Indian pharmaceutical companies possess competitive skills in chemical synthesis and process engineering; the companies can leverage these skills to develop new chemical entities
• Some other potential areas of development include medicinal and aromatic plants, animal biotechnology, aquaculture and marine biotechnology, seri biotechnology, stem cell biology, environmental biotechnology, biofuels, biopesticides, human genetics, genome analysis, and others
Others
OPPORTUNITIES
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Contents Advantage India Market overview and trends Growth drivers Success stories: Biocon Opportunities Useful information
For updated information, please visit www.ibef.org
Biotechnology
MARCH2013
3333For updated information, please visit www.ibef.org USEFUL INFORMATION
Industry Associations
Association of Biotechnology Led Enterprises (ABLE)# 123/C, 16th Main Road, 5th Cross, 4th BlockNear Sony World Showroom/Headstart School Koramangala, Bengaluru - 560034Phone: 91 80 41636853 25633853E-mail: [email protected]: www.ableindia.org
All India Biotech Association (AIBA)"VIPPS Center" 2. Local Shopping Centre Block EFGH, Masjid Moth, Greater Kailash-II, New Delhi - 110048Tel: 91 11 29211487 (Direct), 29220546/547Fax: 91 11 29223089, 29229166Email: [email protected] Website: www.aibaonline.com
Biotechnology
MARCH2013
3434For updated information, please visit www.ibef.org
Glossary→ Bt: Bacillus thuringiensis→ CAGR: Compound Annual Growth Rate→ CRO: Contract Research Organisation→ DNA: Deoxyribonucleic acid→ FYP: Five Year Plan→ GCP: Good Clinical Practice→ INR: Indian Rupee→ NBTB: National Biotechnology Board→ OAD: Oral anti-diabetic drugs→ R&D: Research And Development→ FY: Indian financial year (April to March)
→ So FY10 implies April 2009 to March 2010→ USD: US Dollar
→ Conversion rate used: USD1= INR48→ Wherever applicable, numbers have been rounded off to the nearest whole number
USEFUL INFORMATION
Biotechnology
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Biotechnology
MARCH2013
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