biomatters - spring 2011

BioMattersA MichBio Publication Showcasing Michigan’s Biosciences Industry

S P R I N G 2 011

VC Experience and Vision for Michigan BioCompanies

A New GoverNor BriNGs

Also Featured:

From Mind to Market: The Network of Support for Michigan Entrepreneurs

Profiles of Michigan Companies Traveling Down the Commercialization Highway

Michigan Boasts a Wealth of High-Tech Talent and a Workforce Pipeline to Match

In This Issue:

2011 Michigan Biosciences Directory and Resource Guide

BioMatters | Spring 20111

G O V E R N O R ’ S M E S S A G E

Dear Friends,

Each and every day, people depend on the products of Michigan entrepreneurs in countless

aspects of daily life. We are the state that moved the world into a new industrial age and built

America’s middle class. We take great pride in our past successes and people — like Herbert Dow,

Henry Ford, W.K. Kellogg, and Dr. William Upjohn — who made history from right here in Michigan.

Today people like you are moving Michigan into a new era of innovation.

All across Michigan the bioscience sector is creating a new backdrop for our economy.

Our world class colleges and universities have partnered with public and private sector leaders

to make Michigan the home of one of America’s strongest and fastest growing biosciences sectors.

From 2005 to 2009, nearly a half billion dollars was invested in our biosciences sector, and

we continue to attract venture capital and see more and more startup companies. Moreover, our

state’s quality of life, rich natural resources and distinctive charm make Michigan a great place

to work and raise a family. We are committed to keeping the Great Lakes State a place that

transforms creativity into opportunity.

Sincerely,

Rick Snyder, Governor of Michigan

Ideal incubator space for life sciences or high-technology companies.

• Standard lab amenities and options for customization

• Mini labs of ten lineal feet of bench space with cabinetry

• Locations ranging from 300 to 1,500 square feet

• Access to analytical instrumentation and engineering tools, including a thermogravimetric analyzer (TGA), differential scanning calorimeter (DSC), fume hood and bio-safety cabinet

• Affordable rates

• Office and meeting space available

Monroe Avenue Incubator 1345 Monroe Avenue NWMichigan Street Incubator 301 Michigan Street

For more information contact: Rich Cook, Venture Center Director West Michigan Science & Technology Initiative Cook-DeVos Center for Health Sciences Grand Valley State University P: 616.331.5840 | [email protected] | www.wmsti.org

Our incubators offer:

2BioMatters | Spring 2011

Innovate. Accelerate. Michigan.

Clinical TrialsBarbara Ann Karmanos Cancer Center (Detroit) Designated by the National Cancer

Institute as one of only 13 Centers of Excellence in oncology in the U.S., and the only

Michigan hospital focusing solely on cancer. www.karmanos.org

ClinXus (Grand Rapids) A nonprofit, life sciences alliance, dedicated to benefiting

human health through participation in innovative, early phase biomarker and

molecular-based trials. www.clinxus.com

Detroit Clinical Research Center (Detroit) A health research institution that supports

clinical studies at and collaborates with hospitals and medical facilities in Michigan,

North America and internationally. www.dcrc.us

Jasper Clinical Research and Development (Kalamazoo) An independent phase I

clinical pharmacology service provider specializing in innovative early clinical

research studies. www.jasperclinic.com

Michigan Institute for Clinical & Health Research (Ann Arbor) Enables

and enhances clinical and translational research by integrating education, career

development, infrastructure, and support to catalyze research in the laboratory, clinic,

and community. www.michr.umich.edu

Contract Research OrganizationsAscendant MDx Laboratory Sciences (Farmington Hills) A new kind of clinical lab

for diagnostic tests focused on making the laboratory services experience easier for

patients and healthcare providers. http://ascendantmdx.com

Ash Stevens (Detroit) A world leader in the development, manufacture and registration

of small molecule APIs. www.ashstevens.com

Bryllan LLC (Farmington Hills) Contract manufacturing services to the global

biotechnology and pharmaceutical industry with a focus on potent and cytotoxic

compounds in novel delivery mechanisms. www.bryllan.com

Grand River Aseptic Mfg. (Grand Rapids) A pharmaceutical contract manufacturing

organization (CMO) primarily supporting early stage clinical trials (Phase I and II).

www.grandriverasepticmfg.com

JHP Pharmaceuticals (Rochester) Manufactures and sells brand aseptic injectable

pharmaceuticals in hospital/clinical settings, and provides contract manufacturing

services for global pharmaceutical companies. www.jhppharma.com

Kalexsyn (Kalamazoo) Expert medicinal chemistry services, including synthetic

design SAR and general drug development consulting, medicinal chemistry synthesis,

parallel and combinatorial synthesis, process improvement/development, stable label

compound. www.kalexsyn.com

Medigenix LLC (Novi) Offers preclinical testing, hybridoma core services and

mouse surgical models at a state-of-the-art microsurgery suite and vivarium.

www.medigenix.com

MPI Research (Mattawan) The world’s third-largest organization offering nonclinical

and early clinical research and development services for the pharmaceutical biotech-

nology, medical device and animal health industries. www.mpiresearch.com

MPR Development Group (Farmington Hills) A full-service global clinical research

and development organization that assists pharmaceutical and biotechnology

companies to bring new therapies to patients efficiently. www.mpr.com

VPCI-Inc. (West Bloomfield) Advanced consulting services, including worldwide

regulatory, manufacturing and business development for the pharmaceutical and

biotech industries. http://vpcint.com/index.html

Research & DevelopmentCerenis Therapeutics (Ann Arbor) A pharmaceutical company focused on the

discovery, development and commercialization of breakthrough HDL-related therapies

for the treatment of cardiovascular and metabolic diseases. www.cerenis.com

Wherever you are in the world, wherever you are in the R&D process, Michigan bioscience companies and organizations have the expertise, technologies, development understanding, and talent to support your endeavor.

Visit us in the Michigan Pavilion #1337 at the 2011 BIO International Convention. Chat with representatives of the following companies, just a sampling of what we have to offer…it’s Pure Michigan.


Innovate. Accelerate. Michigan.

Compendia Bioscience (Ann Arbor) Dedicated to applying the global collection

of cancer genomic data to enable the discovery and development of better cancer

diagnostics and treatments. www.compendiabio.com

Esperion Therapeutics (Plymouth) Discovers and develops therapies to prevent,

treat, and reverse cardiovascular and metabolic diseases. www.esperion.com

Everist Genomics (Ann Arbor) An emerging biotechnology company focused on

delivering the promise of personalized medicine. www.genetics2.com

GeneCodes (Ann Arbor) An international software firm specializing in bioinformatics

software for DNA sequence analysis. www.genecodes.com

Innovative Research (Novi) Supplies researchers with dependable human

and animal biological, coagulation proteins, antibodies and EUSA kits.

www.innov-research.com

Lumigen, Inc., (Southfield) (a Beckman Coulter Company) is an ISO 9001:2008

Registered Corporation, and is one of the world’s largest suppliers of chemiluminescent

reagents to the clinical immunodiagnostics market. www.lumigen.com

RealBio Technology (Kalamazoo) Commercializing leading-edge cell and tissue

culture technology that supports the growth, expansion, differentiation and collection

of human and non-human tissues and cells. www.realbiotechnology.com

TSRL (Ann Arbor) An oral drug delivery specialty firm. www.tsrlinc.com

Tech Transfer/CommercializationOakland University Center for Biomedical Research (Rochester Hills)

Promotes and supports biomedical research and education at Oakland University

and allied institutions. www2.oakland.edu/cbr

Southwest Michigan Innovation Center (Kalamazoo) A 69,000 square-foot business

incubator/accelerator that provides support and assistance to nurture the formation,

survival, and growth of innovative, entrepreneurial, life science businesses.

www.kazoosmic.com

TechTown (Detroit) The place where state-of-the-art work space, business support

and community development come together. www.techtownwsu.org

University Research Corridor (Lansing) An alliance of Michigan’s three leading

research institutions: Michigan State University, the University of Michigan and Wayne

State University. www.urcmich.org

Van Andel Institute (Grand Rapids) Committed to improving health and

enhancing lives through disease research and science education. A primary focus

on cancer research, but studies on diseases such as osteoporosis, Parkinson disease,

and diabetes as well. www.vai.org

Local PartnersAnn Arbor SPARK (Ann Arbor) The driving force in establishing the Ann Arbor region

as a desired place for business expansion and location by identifying and meeting the

needs of business at every stage. www.AnnArborUSA.org

Southwest Michigan First (Kalamazoo) The catalyst stimulating growth across the

Kalamazoo Region. www.southwestmichiganfirst.com

The Right Place (Grand Rapids) Develops and implements comprehensive

strategies to retain, expand and attract businesses vital to the west Michigan region’s

long-term health. www.rightplace.org

Wayne County (Detroit) Offers a first-class business environment, a top-rated

international airport, diverse residential areas, expansive parks, and a multitude

of recreational and cultural activities. www.co.wayne.mi.us

Genesee Regional Chamber of Commerce (Flint) The voice of business and

community advocacy in Genesee County. www.thegrcc.com

Hosted by:

www.michigan.org www.michbio.org

®


Michigan’s Biosciences Industry Welcomes You! Michigan is home to a strong biosciences industry with a rich legacy of industry

leaders like Parke-Davis Pharmaceuticals-Upjohn/Pharmacia-Pfizer, Stryker, Perrigo,

Dow Chemical, Kellogg, Terumo, MPI Research, Emergent BioSolutions, Neogen, BD and

Beckman Coulter, among others. Our over 550 bioscience companies, academic research

centers and clinical institutions reflect the breadth of pharma/biotech, medical

devices/equipment, research products and diagnostics, informatics, ag-bio, bio-defense,

industrial and environmental biotechnology, medical/laboratory testing and clinical

research.

Our bioscience companies have a remarkable track record of investment, growth,

and return, despite recent economic challenging times. Michigan has witnessed an

overall 13% increase in number of bioscience companies and an almost 6% increase in

bio-industry employment in the last ten years. More than 120 companies launched in the

same period.

The State of Michigan provided $325 million in support to bioscience companies

during the last decade, as well as an additional $46 million of investment by the state’s

fund-of-funds that were directed to biotech start-ups. Coupled with other state resources

like our Pre-Seed Capital Fund, Micro-Loan Program, Angel Investor Tax Credit, and an

unrivalled statewide network of SmartZonesSM that provide business acceleration and wet

lab incubator services, means that Michigan’s biosciences companies benefit from a

strong ecosystem that supports commercial growth from ideas to markets.

The current issue of BioMatters continues to present the faces, organizations and

initiatives that represent Michigan’s biosciences community. Whether you’re already

here or looking in from the outside we welcome you to learn more about who we are,

what we do, how we achieve it and where we’re going with our biosciences industry.

I invite you to visit us at Booth #1337 during the BIO International Convention in

Washington, DC from June 27-30, 2011. Or simply contact me at [email protected]

and let MichBio, the state’s biosciences trade association, show you how to access

companies, services, resources, markets and information related to our state’s robust

bio-industry.

Stephen Rapundalo, Ph.D.

President and CEO, MichBio

P R E S I D E N T ’ S M E S S A G E

P R O F E S S I O N A L S TA F F

C O N TA C T I N F O R M AT I O N

Stephen T. Rapundalo, Ph.D.

President and CEO

[email protected]

734.527.9144

Jayne Berkaw

Director,

Marketing and Communications

[email protected]

734.527.9147

Heather Kusiak

Manager,

Operations and Membership

[email protected]

734.527.9150

Nancy Marcotte

Manager, Finance

[email protected]

734.527.9145

Physical Address

3520 Green Court, Suite 150

Ann Arbor, Michigan 48105-1579

Mailing Address

P.O. Box 130199

Ann Arbor, Michigan 48113-0199

Phone

734.527.9150

Fax

734.302.4933

Website

www.michbio.org

Email

[email protected]

SAVE THE DATECONFERENCE HIGHLIGHTS: • The Michigan Emerging Biosciences Showcase • Concurrent track sessions in Pharma, Medical Device, Emerging Business and Bio-Based Technologies

Over 70% of attendees are bio-executives.

ExHIBITOR/SPONSOR INFORMATION AND RESERVATIONS Contact Erin • 734.677.0503 • [email protected]

7th Annual MichBio Expo & Conference November 2-3, DeVos Place, Grand Rapids

• Bio-Policy Roundtable • Manufacturing Session • CEO Dinner Forum • Poster Session • Facility Tours and much more!

BioMatters | Spring 2011 6

CORPORATE SPONSORS

P L AT I N U M

G O L D

S I LV E R

B R O N Z E

®

O F F I C E R S , D I R E C TO R S A N D C O M M I T T E E S

PATRONAsh Stevens, Asterand,

Lumigen, Phadia US, Inc., Terumo, Varnum

FRIENDKalexsyn

SUPPORTERBiotechnology Business Consultants,

sanofi-aventis U.S., West Michigan Science &

Technology Initiative

M E D I A

ExECUTIVE OFFICERSChairmanStephen Munk, Ph.D.Ash Stevens, President and CEO

Vice ChairmanDavid ZimmermannKalexsyn, Inc., Chief Executive Officer

President and CEOStephen T. Rapundalo, Ph.D.MichBio, President and CEO

Secretary Christina DeHayesAsterand plc, General Counsel

Treasurer Matthew L. McCollErnst & Young LLP, Partner

DIRECTORSJ. Patrick ElliottTerumo Cardiovascular Systems Corp.Vice President, Business Development

David Felten, M.D., Ph.D.Beaumont Hospitals, Research InstituteVice President, Research and Medical Director

James Freeman, Ph.D.Pfizer Animal HealthVice President, Laboratory Sciences

Teri Grieb, Ph.D.U of M Medical School, Office of ResearchDirector of Administration for ResearchOffice of Research and Graduate Studies

Mark KielbAltarum InstituteChief Financial Officer

Paul MorrisAlixPartners, LLP Finance Manager, National Enterprise Improvement Practice

Brent Mulder, Ph.D.Van Andel Research Institute Director, Office of Technology Transfer

Stephen Munk, Ph.D.Ash Stevens President and CEO

Stephen T. Rapundalo, Ph.D.MichBio President and CEO

Jennifer Rice, D.V.M., MSc, Ph.D.Neogen Corporation Senior Scientific Officer

John J.H. Schwarz, M.D.Family Health CenterPhysician,Former U.S. Representative

Christopher J. SteinFerndale Pharma Group, Inc. Senior Vice President, Corporate Development

Eric StiefAutoHarvest FoundationSenior Vice President

Karen Studer-RabelerCoy Manufacturing/Coy Laboratory ProductsGeneral ManagerVice President, Business Development

Bill WorzelEverist Genomics, Inc.President and CEO

David ZimmermannKalexsyn, Inc.Chief Executive Officer

COMMITTEESClinical TrialsFinancial Services and Risk ManagementIntellectual Property and LegalMembership and MarketingProgramsPublic Policy

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BioMattersT A B L E O F C O N T E N T S

A D V E R T I S E R S

Ash Stevens ............................................................... 8

C2RS ........................................................................ 16

Doeren Mayhew ..................................................... 17

Grand Valley State University ................................ 23

Kalexsyn, Inc. .......................................................... 23

Kettering University ................................................. 7

MichBio ................................................................. BC

Rader, Fishman & Grauer ...................................... 16

Southwest Michigan Innovation Center ............... 11

Terumo Cardiovascular Systems ........................... 17

Trialon Corporation ............................................... 23

University of Michigan ............................................ 4

West Michigan Science & Technology Initiative ..... 1

Michigan Economic Development Corp. ............ IFC

Michigan State University ........................................ 8

MPI Research ......................................................... 11

Oakland University ................................................ 17

Pharmacision ......................................................... 16

Pfizer ..................................................................... IBC

Quest Research Institute ........................................ 23

6 MichBio Corporate Sponsors, Officers, Directors and Committees

15 New Governor Looks to Cultivate Climate for Success

Feature StOry: a New era for Michigan: economic Gardening to Grow State’s Bio-Industry

22alternative Business Model Drives Private Wet Labs

26 PharMaCeu- tICaLS aND theraPeutICS: Problem-Solving Specialty Drug Maker is a Life Saver

The following MichBio members are featured in this issue of BioMatters:AlphaCore Pharma, LLC, Ann Arbor SPARK , Ascendant MDx, Barbara Ann Karmanos Cancer Center, Genemarkers, LLC, Ferris State University, Grand Valley State University,

Henry Ford Community College, Intervention Insights, Medical Main Street, Michigan Economic Development Corp., Michigan Research Institute, Michigan Small Business & Technology Development Center, Michigan State University, Michigan Technological University, Neogen, Pfizer, PhRMA, Southwest Michigan First, Southwest Michigan Innovation Center,

Tangent Medical Technologies, Inc., TechTown, University of Michigan, Wayne State University

Subscribe to BioMatters:Visit www.michbio.org and click “register Now” or call 734.527.9150.

18eCONOMIC DeVeLOPMeNt: From Mind to Market Michigan’s robust Frame-work for Moving Companies Forward

36 GueSt OPINION: The Bio-Industry — an Indisputable and essential economic Driver for Michigan

32WOrKFOrCe DeVeLOPMeNt: a Strong Pipeline Feeds Michigan’s Wealth of Biotalent

PrOFILe: ash Stevens Builds on Strengths...and Wins!

1234Incentives Matter: economic

Development agencies Work to attract and retain Bioscience Jobs and talent

29 eNtrePreNeurS: after the elevator Speech

37DIreCtOry & reSOurCe GuIDe

28


That was the conclusion of a

2009 study released by PhRMA and

MichBio, which found that “Michigan

has the assets to support and grow bio-

science, particularly in the presence

of its major research universities.” In

FY 2008, bio-industry payrolls reached nearly

$2.5 billion and contributed $9.5 billion to the state’s

GDP, while directly employing more than 37,000

people. Total academic bioscience R&D expenditures

were $951 million in 2008.

Michigan is home to more than 550 bioscience

enterprises from pharmaceuticals and therapeutics

(including nutraceuticals), medical device and equip-

ment companies, diagnostics and research products, to

bio-based technologies and bio-agriculture. The state’s

contract research industry alone has the depth to

handle business globally at any stage of pharmaceutical

and medical technology development.

Michigan’s SmartZonesSM fuel a robust pipeline

of bioscience companies through their business and

wet-lab incubators — 126 new start-ups since 2002

alone. Collaborations between local universities,

industry, research organizations, government agencies

and other community resources nurture entrepreneurial

ventures with business assistance and access to funding

sources. Michigan’s bio-companies have been fueled

by $440 million in venture capital investment from

2004 to 2009. From the tip of the Upper Peninsula

to the bustling Lower Peninsula, the state’s vibrant

biosciences industry is “Pure Michigan.”

The study points out that

bioscience expenditures totaled $951 million with industry payrolls reaching nearly $2.5 billion.

Bioscience Industry is Broad, Deep in Michigan


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12

FEATURE STORY


Economic Gardening to Grow State’s Bio-Industry

A New Era for Michigan:


If biosciences leaders in Michigan could harvest a dream team to lead state government,

it might look something like this:

The governor would be a successful technology

business executive and venture capitalist who

knows what it takes to grow bio-related compa-

nies. Rather than a skilled orator, the governor

would sound more like a CPA and might even

come off as being kind of nerdy.

His pick to run the state’s economic develop-

ment agency would possess deep experience

on the local level in a region rich with bio-

technology and medical-related businesses,

supplemented by life sciences research at one

of the world’s premiere research universities.

Position players in his economic develop-

ment agency would specialize in talent retention

and acquisition, entrepreneurship and strategic

partnerships.

That’s exactly what the state is getting in the

new administration of Gov. Rick Snyder, who

took office on Jan. 1.

Snyder, who was president and interim CEO

of computer-maker Gateway Inc. in the 1990s,

returned to his native Michigan in 1997 and started

Ardesta LLC, a $100 million venture capital fund

that invested mainly in technology companies.

“It’s a field I enjoyed investing in and did

pretty well,” Snyder said in a telephone interview

with BioMatters. “We’ve come a long way in the

past couple of decades in Michigan” in the biosci-

ences. “We’ve developed a strong infrastructure.”

MEDC HOLDS REINS FOR STATE BIOSCIENCE MATTERS As it has in past administrations, the major

support for biosciences will be housed at the

Michigan Economic Development Corporation,

headed by Mike Finney.

A native of Saginaw, Finney was serving

as president and CEO of Greater Rochester

Enterprise, an economic development agency in

Rochester, N.Y., when Snyder recruited him five

years ago to run Ann Arbor SPARK. Snyder was

chairman of the Ann Arbor economic develop-

ment agency at the time.

During his campaign for governor, Snyder

criticized the MEDC for its growing use of pricy

tax incentives to entice companies to expand

or locate in Michigan during the eight years

Jennifer Granholm served as governor. Snyder

was a former chairman of the MEDC executive

committee during the administration of Gov.

John Engler.

Michigan granted $220.9 million in brown-

field and Michigan Economic Growth Authority

tax credits just in the past year. Those credits and

hundreds more granted in previous years will

cost the state nearly $800 million in tax revenue it

otherwise would have collected in 2012 and 2013.

Snyder proposed replacing the Michigan

Business Tax, which taxes gross receipts and

profit, with a 6 percent corporate income tax.

The legislature approved the sweeping change

in May.

Virtually all business tax credits in the

complex MBT will be eliminated in favor of a

simplified profits tax that Snyder maintains will

lead to more jobs and a fundamentally stronger

state economy.

Only large “C” corporations will pay

the corporate income tax. All other types of

businesses, including partnerships, sole pro-

prietorships and limited liability corporations

will not be subjected to the tax, which includes

start-up and other young biosciences companies.

The new corporate income tax will take effect in

October.

“We’re doing away with a lot of the incentive

programs,” Finney said. “Our focus is going to be

on reducing the cost of business for everybody.”

THREE-LEGGED STOOL STRATEGY GUIDES SUPPORT FOR BIOSCIENCES The MEDC’s new economic development

strategy essentially is a three-legged stool that

focuses on supporting existing businesses in the

state, attracting new investment and promoting

a more entrepreneurial economy.

Granholm’s targeted industry strategy,

which focused state resources on life sciences,

advanced automotive technologies, alternative

energy and homeland security also is being

eliminated.

Virtually all business tax credits in the complex MBT would be eliminated in favor of a simplified profits tax that Snyder maintains will lead to more jobs and a fundamentally stronger state economy.

By Rick Haglund

Michigan governor rick Snyder SayS the State haS built a Strong bioScienceS infraStructure.

Mike finney, ceo of the Medc, proMoteS a Multi-pronged approach to help SMall, growth-oriented coMpanieS expand and create jobS – “econoMic gardening.”


FEATURE STORY

But Finney said he sees life sciences and

other bio-related companies as an important

segment of the state’s economy. “We want to

be opportunistic,” he said. “The industry has

grown substantially over the past 10 years.

It’s important to keep it on our radar screen.”

The state isn’t totally eliminating

financial support for companies in the

biosciences sector. It’s still spending $25

million a year in an annual competition for

businesses and researchers seeking funding

to commercialize life sciences technologies.

Michigan also will have roughly $50

million available to spend on incentives to

attract new business investment to the state.

And the MEDC is continuing several of its

small-business lending initiatives, including the

successful capital access program, Finney said.

Started more than 20 years ago by Gov.

James Blanchard, the capital access program

uses a small amount of state money to

leverage bank loans for companies having

difficulty finding financing. The program

has generated more than 11,000 business

loans over the past 22 years. It has used

$24.3 million in state money to leverage

$628.7 million in bank funding.

But about 60 percent of the state’s

economic development work in the Snyder

administration will be in the area of “eco-

nomic gardening,” a multipronged approach

to help small, growth-oriented companies

expand and create jobs.

Economic gardening was pioneered

by local economic development officials

in Littleton, Colo. who grew frustrated over

watching companies that had been given

tax incentives to locate there leave after the

credits expired. The city now relies entirely

on economic gardening for job creation.

“It’s a new frontier — almost a new

profession that’s being created,” Rob Fowler,

president of the Small Business Association

of Michigan, said about economic gardening.

Economic gardening is far more complex

than just calling on companies and asking

what Lansing can do to help them. It involves

establishing a new toolbox of services,

including market research, financing help

and expert advice on managing growth.

Rather than offering those services

itself, the MEDC will rely on universities

and organizations such as MichBio and the

Michigan Small Business and Technology

Development Center to provide technical

and business expertise to growing companies

on a contract basis.

His model for assisting companies is

the Michigan Manufacturing Technology

Center, a Plymouth-based organization

that contracts with specialists in finance,

accounting, manufacturing, marketing and

other disciplines to aid small-and-medium-

size manufacturers.

“The MEDC doesn’t have to become the

expert in all these different areas,” Finney

said. “We can contract with groups such as

MichBio and the Michigan Small Business

and Technology Development Center to

provide companies with services as needed

on a project basis.”

The MEDC’s attitude towards partner-

ship with industry groups and regional

organizations is a welcome sign. “We need

an integrated ecosystem that brings together

relevant stakeholders like MichBio to sup-

port bioscience company growth,” said

Stephen Rapundalo, President and CEO

of MichBio. “Doing so will bring to bear

many strengths and resources in a coordinated

manner, thereby making it easier for

companies to gain the assistance they need.”

“We want to be opportunistic,” he (Finney) said. “The industry has grown substantially over the past 10 years. It’s important to keep it on our radar screen.”

11 BioMatters | Spring 201115

Rick Snyder came back to his native Michigan 14 years ago looking

to grow and profit from the state’s technology industries, including

the biosciences.

His $100 million venture capital fund, Ardesta Ventures, invested

in several of Michigan’s most successful tech start-ups, including

HandyLab, an Ann Arbor diagnostic testing firm.

Avalon Investments, another Snyder venture capital firm, in-

vested in HealthMedia, a healthcare software business that was sold

to Johnson & Johnson in 2008. HandyLab and HealthMedia were spun

out of research at the University of Michigan.

But now that he’s governor, Snyder says his goal is to create a

climate in which all kinds of companies can succeed.

“I’m more into creating the best environment for all business and

letting free enterprise work,” Snyder said in a telephone interview

with BioMatters. “How can we develop partnerships with the private

sector? How do we unleash free enterprise?”

To Snyder, the answers to those questions are found in revamping

the state’s business tax structure and overhauling the Michigan

Economic Development Corp. to work more closely with trade groups

and local economic development agencies.

FEATURE STORY

New Governor Looks to Cultivate Climate for Success Those partnerships are what MEDC President Mike Finney calls “open

source” economic development. It’s an acknowledgement that wisdom

about growing businesses resides mostly outside of state government.

Throughout his campaign for governor, Snyder repeatedly talked

about the need to change Michigan’s tax structure, and to make the

MEDC more focused on helping entrepreneurs and less dependent on

doling out tax incentives.

Snyder’s business tax plan, which was approved by the legislature

in May, will replace the complex Michigan Business Tax, which has

profit and gross receipts components, with a simpler 6 percent

corporate income tax. The plan will exempt most small firms

and cut business taxes overall by $1.7 billion.

“Our business tax plan is about creating a level playing field,”

Snyder said. “It’s a flat, simple income tax. Young companies that aren’t

making money yet shouldn’t have to deal with a gross receipts tax.”

But Snyder’s budget plan for fiscal year 2012 proposes about $1.5

billion in spending cuts, including a minimum 15 percent reduction

in university funding. That could threaten some of the research and

other work done at the universities that leads to new companies

and products in the biosciences, though the bulk of such efforts is

supported by federal NIH funding typically.

Snyder said the cuts, though painful, are necessary to restore

Michigan’s long-term financial health, and allow future investments

in universities and other institutions that aid the economy.

“In the short term, we need shared sacrifice to straighten out

the structural problems we have,” he said. “But by 2013, the higher

education cuts are over with.”

One of Michigan’s challenges in developing entrepreneurial busi-

nesses is that successful young companies often are sold to larger

companies and moved out of state. That happened most recently with

HandyLab, which was sold in 2009 to New Jersey medical devices giant

Becton Dickinson and Co. for $275 million. Snyder was chairman of

HandyLab at the time of the sale.

“When companies are moved out of state, the number one reason

usually is talent and then capital availability,” Snyder said. “We have

the technical talent. We need to work on acquiring more management

talent and venture capital.”

But Snyder said he sees a bright future for the biosciences. The

industry not only has grown in terms of the number of companies,

but also has expanded broadly across the state.

“We have a good legacy and a strong core,” he said. “We have

labs and specialty equipment available for start-up companies. There

are a lot of good opportunities here. We’ve come a long ways.”

“I’m more into creating the best environment for all business and letting free enterprise work,” Snyder said in a telephone interview with BioMatters. “How can we develop partnerships with the private sector? How do we unleash free enterprise?”

a background that includeS inveSting in SucceSSful bioScience ventureS giveS governor rick Snyder unuSual inSight into the needS of growing coMpanieS.

Snyder said he sees a bright future for the biosciences. The industry not only has grown in terms of the number of companies, but also has expanded broadly across the state.


Officials at several companies and nonprofits that help

young biosciences companies grow said they support the

Snyder administration’s economic development strategy.

“In general, I think it will have a positive impact regard-

less of industry,” said James Richter, president of the Michigan

Research Institute, an Ann Arbor-based nonprofit corporation

that commercializes biosciences research and operates a wet

lab business incubator. “The tax change unburdens a lot of

companies.”

Some 95,000 companies that now have tax liability under

the MBT wouldn’t even have to file a tax return under the

profits tax. The convoluted MBT and Granholm’s targeted

industry approach wasn’t sustainable, said Kenneth Massey,

director of research and clinical operations at Lifeline

Ventures, a Farmington Hills-based company that provides

venture capital and leased space to life sciences companies

in mid-to-late stages of growth.

“The problem is government isn’t particularly skilled at

business development,” Massey said. “If you level the playing

field in the tax structure, you start to allow companies to

develop. I think that’s where we want to be.”

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Bio Matters - 2011:Layout 1 4/2/2011 8:58 AM Page 1

ECONOMIC DEVELOPMENT


From Mind to Market Michigan’s Robust Framework for Moving Companies Forward

Training?

Wet Lab?

Staff?

Business Mentoring?

Access to Capital?

Financial Counseling?

Networking?

Office Essentials?

Equipment?

18


By Rick Haglund

In 2003, a group of community leaders from Kalamazoo showed up unexpectedly at a Michigan Life Sciences Corridor Steering Committee meeting with an emergency request for $2 million in funding. Pfizer had just announced it was cutting 1,200 jobs in Kalamazoo. Local officials said

they needed fast cash to fund an ambitious plan that would allow Pfizer scientists to stay in Kalamazoo

and start their own companies.

The funding from Michigan’s portion

of a federal tobacco lawsuit settlement was

granted, aiding the opening that year of the

Southwest Michigan Innovation Center, a

69,000 square-foot life sciences business

incubator and accelerator that operates on

a $2 million annual budget.

Located in the Western Michigan

University Business Technology Research

Park, the modern, two-story, brick-and-steel

structure provides wet labs and professional

office space young biosciences companies

otherwise could not afford.

“We are in such a nice setting that when

our companies host potential investors; it

offers them a lot of credibility,” said Robert

DeWit, president and chief executive officer

of the Southwest Michigan Innovation Center.

It’s also important for start-up companies

seeking federal grants to have a business

address, which the Southwest Michigan In-

novation Center provides them. “Having a real

address is critical in the granting process,”

he said. “The federal government doesn’t like

to send checks to a home address.”

INCUBATORS PROVIDE KEY SERVICES The Southwest Michigan Innovation

Center is just one of more than a dozen pub-

licly supported incubators providing crucial

services to biosciences start-ups. Most

are located in the state’s 15 SmartZonesSM,

which are technology clusters that promote

collaboration among universities, industry,

research organizations and government.

Since it began operations nearly a decade

ago, the Southwest Michigan Innovation

Center has graduated five companies, result-

ing in the creation of 342 jobs in the area.

The center currently has 15 tenants and

has provided services to 25 other companies.

DeWit said demand for space is increasing

as Michigan recovers from a deep recession.

“Having a real address is critical in the granting process,” he said. “The federal govern-ment doesn’t like to send checks to a home address.”

Since it began operations nearly a decade ago, the Southwest Michigan Innovation Center has graduated five companies, resulting in the creation of 342 jobs in the area.

the SouthweSt Michigan innovation center offerS bioScience StartupS wet lab Space and buSineSS accelerator ServiceS that Support the developMent of both their Science and their buSineSS.


ECONOMIC DEVELOPMENT

“One of the things I think we do par-

ticularly well is offer phenomenal support

from a business or a science perspective,

or a combination of the two,” said DeWit,

who was a research scientist for 25 years,

mostly at Pfizer.

Increasingly, incubators are linking

with each other to provide a broad array of

services. For entrepreneurs, that means the

ability to access programs and expertise that

may not be available at a local incubator.

“We are being encouraged (by state

officials) to collaborate closely in a way we

perhaps haven’t done before. I think that’s

quite exciting,” said Randal Charlton, execu-

tive director of TechTown, an incubator

and business accelerator in Detroit. “We’re

developing a statewide network that can be

quite powerful, particularly for life sciences.”

TechTown, a brainchild of then Wayne

State University President Irvin Reid, was

incorporated in 2000 and opened its first

incubator in midtown Detroit in 2004.

That incubator, known as TechOne, is

a five-story, 120,000 square-foot building

designed by renowned architect Albert

Kahn in the early 1920s. It formerly housed

Chevrolet Creative Services and was donated

to TechTown by General Motors Co.

TechOne has 243 current business ten-

ants, which may seem surprising given the

negative publicity about Detroit’s declining

population and financial woes.

“We’re full,” Charlton said. “Many of our

tenants are very early stage companies.”

Among them are MitoStem, which is en-

gaged in stem cell research; ApoLife, which

is using yeast expression technologies in the

development of therapeutic antibodies to

treat cancer and other diseases; and Clean

Emission Fluids Inc., a company that manu-

factures equipment for biodiesel fueling and

other fluids.

Those companies take advantage of a

variety of services, including wet lab space,

financing and management help, access to

technology, and even more routine services

such as printing.

TechOne Printing is a low-cost service

that can print everything from business

cards to books and is available to entrepre-

neurs not located in the incubator. Charlton

jokingly refers to it as “Kinko’s on steroids.”

A second incubator, known as TechTwo,

is under construction in a building that

formerly housed a Cadillac dealership. The

building, which has a waiting list of com-

panies ready to occupy it, is scheduled to

open later this year.

The two TechTown incubators are part of

a 43-acre technology park that includes lofts,

a charter high school and offices occupied by

Wayne State and Henry Ford Health System.

TechTown’s biggest success story is its

first tenant, Asterand, which was founded

by Charlton in 2000. The company, which

provides human tissue for drug discovery

scientists, merged with English company

Pharmagene and went public in 2006. Its stock

is traded on the London Stock Exchange.

Charlton retired from Asterand in 2006

to become TechTown’s executive director.

Ann Arbor SPARK, a local economic

development agency, operates three business

incubators in Washtenaw County. One of

them, the Michigan Life Science and Innova-

tion Center, houses 12 businesses, including

nine life sciences start-up companies.

Increasingly, incubators are linking with each other to pro-vide a broad array of services. For entrepreneurs, that means the ability to access programs and expertise that may not be available at a local incubator.

Companies take advantage of a variety of services, in-cluding wet lab space, financing and management help, access to technology, and even more routine services such as printing.

hilary wagner, a ScientiSt at ceetox, an incubator tenant at kalazaMoo’S SouthweSt Michigan innovation center, perforMS a biocheMical aSSay teSt. ceetox iS a cro focuSed on in vitro toxicity Screening of potential drug candidateS and cheMicalS.


Skip Simms, vice president of entrepre-

neurial business development at SPARK, said

the state’s creation of a life sciences corridor

more than a decade ago and incubator fund-

ing from the state through SmartZonesSM are

starting to pay off.

“We’re creating a cluster and I think that

cluster is beginning to blossom,” he said.

“We’re not as strong as Boston or San Diego,

but we’re on our way.”

There are incubators and business ac-

celerator services available in SmartZonesSM

throughout the state, from Detroit to Hough-

ton in the Upper Peninsula.

MI-SBTDC SUPPORTS ENTREPRENEURS STATEWIDE But start-ups and other young companies

with growth issues don’t need to be in an

incubator to get help.

That’s where the Michigan Small Business

& Technology Development Center comes

in. Known by the acronym MI-SBTDC, the

center provides counseling, training, research

and advocacy for new ventures, existing

small businesses and innovative technology

companies in 30 locations around the state.

Some of those locations are at incubators

and accelerators located in SmartZonesSM.

“We’re an overarching state entity that

provides services for everyone,” said Sandra

Cochrane, a technology business consultant

at MI-SBTDC, which is headquartered at

Grand Valley State University in Grand

Rapids. “We work with the incubators

and entrepreneurs, offering another layer

of support.”

The center counsels about 6,000 businesses

a year. In 2009 MI-SBTDC helped client com-

panies raise about $250 million in capital. It also

helps local communities establish incubators

and provide other services to entrepreneurs,

start-ups and growth-oriented businesses.

“Clients are served best when they are

able to connect with the ecosystems of their

local communities,” said Cochrane, who heads

the life sciences team at MI-SBTDC.

The major need continues to be financing,

Charlton said. However, Michigan’s capital

formation outlook has grown, with many more

venture capital firms in place, and investors

from across the country recognizing exciting

opportunities with good ROI prospects.

Charlton said many entrepreneurs also

aren’t aware of the extent of low-cost help

they can get from universities. Incubators like

TechTown are, in part, access portals to univer-

sity research and other services. “Collectively,

we’ve got phenomenal resources,” he said.

The state’s creation of a life sciences corridor more than a decade ago and incubator funding from the state through SmartZonesSM are starting to pay off.

a broad-baSed coalition Made poSSible the Michigan life Science and innovation center in plyMouth with itS 57,000 Sf of incubator Space including State-of-the-art labS, officeS and conference rooMS.

detroit’S techtown incubator currently houSeS 243 tenantS, and it iS renovating another building to add even More Space. tiSSue banking SucceSS Story, aSterand, waS itS firSt tenant.

“Clients are served best when they are able to con-nect with the ecosystems of their local communities,” said Cochrane, who heads the life sciences team at MI-SBTDC.

Sandra cochrane


Alternative Business Model Drives Private Wet LabsECONOMIC DEVELOPMENT

Supplementing the more than a dozen state-sponsored

business incubators and accelerators are a small, but growing,

network of private-sector companies that play an important

role in helping biosciences companies grow.

One company that combines elements of the venture

capital and incubator models is Farmington Hills-based Lifeline

Ventures, a firm that offers 325,000 square feet of lease and

incubator space on a 10-building campus, as well as providing

venture capital.

Venture capital firms usually provide a certain level of

financing, such as pre-seed or mezzanine financing. Many

venture capital companies also look for a certain rate of

return or exit date when they can recoup their investment.

Lifeline Ventures takes a more patient approach, said Ken

Massey, director of research and clinical operations. While

it likes to acquire a majority stake in the companies in which

it invests, Lifeline Ventures has no stringent timing criteria.

“We don’t look for a specific rate of return or exit date,”

he said. “We actually look at an investment as if we will be

there until there is an offer to buy us out or there is a path

to commercialization. It’s a little outside the box.”

Many entrepreneurs are unwilling to give up majority

control in their companies. But Lifeline’s approach appeals to

founders who want to concentrate on developing a product and

not spend time on obtaining continuous rounds of financing.

Lifeline also provides services such as marketing, human

resources and obtaining patents. Manoj Bhargava, who also

developed the 5-Hour Energy drink, founded the company

in 2007 as MicroDose Life Sciences.

Staffed mainly by former Pfizer Inc. scientists and employ-

ees, Lifeline has made only a few investments, including one in

UltraLinq Healthcare Solutions Inc., which offers a web-based

system for viewing and storing medical images such as ultra-

sounds.

It also rents space to Ascendant MDx, which provides

molecular diagnostic testing services to healthcare providers.

It recently moved work from Illinois and Tennessee and employs

about 150 people at the site.

Massey said Lifeline Ventures has reviewed about 100 busi-

ness plans of companies from around the country. It hopes to

invest in some and move them to Michigan.

Another approach to product commercialization and business

development is being taken by the Michigan Research Institute,

a private nonprofit corporation started in 2002. Its niche is in

scouring universities, federal labs and private companies for

technologies that can be commercialized in conjunction with

business partners.

“We put together teams of experts, provide the financing

and launch new companies,” said Michigan Research Institute

Founder Jim Richter.

The institute, which operates a wet lab incubator in Ann

Arbor, is partnering with Diamond Automation of Michigan on

a microwave technology to pasteurize eggs, protecting them

from salmonella and avian flu.

Michigan Research Institute’s latest project is the Michigan

Center for Regenerative Medicine in Plymouth, a wet lab

incubator for companies performing adult stem cell research.

The lab, backed by Wayne County and a $2.2 million federal

grant, is expected to open this fall.

Another private business incubator, Vo2 Ventures LLC, in

Farmington Hills, specializes in providing business assistance

for healthcare, biotechnology and life sciences companies.

Headed by Greig Davis, a certified public accountant,

the company offers venture capital financing, entrepreneurial

training, and legal, accounting and other business services.

One company that combines elements of the venture capital and incubator models is Farmington Hills-based Lifeline Ventures, a firm that offers 325,000 square feet of lease and incubator space on a 10-building campus, as well as providing venture capital.

Lifeline’s approach appeals to founders who want to concentrate on developing a product and not spend time on obtaining continuous rounds of financing.


“We put together teams of experts, provide the financing and launch new companies,” said Michigan Research Institute Founder Jim Richter.


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MI BIO-INDUSTRY QUICK FACTS# Bio Companies & Organizations:

>540# Bioscience Jobs:

37,180# Spin-Off Jobs:

102,609Average Bioscience Salary:

$73,394Total Payroll:

$2.5 billionEconomic Impact:

$9.5 billionTotal Bioscience Start-Ups Since 2002:

126

ACADEMIC BIO-RESEARCH UNIVERSITY RESEARCH CORRIDORTotal R&D:

$1.6 billion (#11 in the nation)

Biosciences R&D:

$951 million (#10 in the nation)

# of Biosciences Degrees:

5,548 (#8 in the nation in 2008)

# of Bioscience-Related Patents:

1,871(2004-09)

BIO-INDUSTRY INVESTMENT, COMMERCIALIZATION RESOURCES & INCENTIVESLife Sciences Corridor Fund – 21st Century Jobs Fund:

$323 million(1999-2009)

VC Investments:

$268.7 million(2002-07)

Total $ Raised:

$68.8 million (#11 best in the nation 2009)

DATA


21st Century Investment Fund:

$109 million fund-to-funds$46 million to biosciences Venture Michigan Fund:

$95 million fund-to-funds (2007-09)

MI Pre-Seed Capital Fund

MI Microloan Fund

Angel Investor Tax Credit

R&D Tax Credit

R&D and Bio-Manufacturing Tax Exemption

NOL Carryover

SBIR Match

n Accuri Cytometers

n Ash Stevens

n Assay Designs

n Asterand

n Atek Medical

n Beckman Coulter

n Dow Chemical

n Emergent BioSolutions

n Esperion Therapeutics

n Everist Genomics

n Ferndale Pharma Group

n Housey Pharmaceuticals

n Jasper Clinical R&D

n JHP Pharmaceuticals

n Kalexsyn

n Kellogg

n Lycera

n Medbio

n MPI Research

n NanoBio

n Neogen

n Orchid Orthopedic Solutions

n Oxford Biomedical

n Perrigo

n Pfizer

n Phadia

n Pioneer Surgical

n Rockwell Medical

n Stryker

n Terumo CVS

n Vestaron

A SAMPLE OF BIOSCIENCE COMPANIES IN MICHIGAN


Distribution of Michigan bio-companies by sectorPharma & Therapeutics 22%

Medical Devices/Equipment 36%

Research & Development 19%

Testing/Medical Labs 5%

Information Technology 7%

AgBio & Industrial Biotech 10%

Pharma & Therapeutics

Medical Devices/Equipment

Research & Development

Testing/Medical Labs

AgBio & Industrial Biotech

Information Technology

26BioMatters | Spring 2011

Problem-Solving Specialty Drug Maker

is a Life SaverAccording to the 2009 Drug Trend Report published by Express Scripts, the use of specialized drugs is projected to grow 10-12 percent through 2012, primarily due to approval of novel therapies for conditions that are currently unmet. The report also says

spending on specialty drugs, which include the top three therapy classes—inflammatory conditions, multiple

sclerosis, and cancer—increased 19.5 percent from 2008 to 2009.

According to the 2009 Drug Trend Report

published by Express Scripts, the use of

specialized drugs is projected to grow 10-12

percent through 2012, primarily due to ap-

proval of novel therapies for conditions that

are currently unmet. The report also says

spending on specialty drugs, which include

the top three therapy classes—inflamma-

tory conditions, multiple sclerosis, and cancer

—increased 19.5 percent from 2008 to 2009.

Specialty drugs were not always such big

business. They were hardly even a cottage indus-

try in 1975 when Phil Hagerman went to work

for his father at Diplomat Pharmacy in Flint. But

Hagerman knew there would always be a need

for customized pharmaceutical services.

PHARMACEUTICALS AND THERAPEUTICS

Spending on specialty drugs, which include the top three therapy classes—inflammatory conditions, multiple sclerosis, and cancer—increased 19.5 percent from 2008 to 2009.

by Tom Beaman


“We started out as a traditional phar-

macy, but we were always one that worked

to solve problems,” says Hagerman, who

today is Diplomat’s Specialty Pharmacy’s

president and CEO. “If the doctor asked me

to carry a product that was complicated and

expensive, I just simply found a way to do

it. We very quickly became a niche player

for complicated therapies that the average

pharmacy would not fill. We were one of

the early ones in the nation to start tackling

therapies for AIDS [by finding a way to

atomize the antibiotic Pentamidine to treat

pneumonia associated with the disease].”

Today, with 100,000 clients, Diplomat

is the largest privately held specialty

pharmacy in the nation, with locations in

Michigan, Illinois, Florida and California.

Named one of the fastest growing private

companies by Inc. Magazine, Diplomat’s

sales rose from $370 million in 2009 to

$580 million in 2010. Hagerman forecasts

sales of over $800 million in 2011.

“Many of the drugs we dispense are

limited distribution, which means that only

certain people in the country are contracted

to have them, Hagerman says.” We proactively

manage patients who are seriously ill or who

are on complex, tightly controlled therapies

in a way that traditional drugstores are not

able to do.”

Specialty drugs are just that – special.

They are not the high-volume, low-margin

hypertensive or statin products that are

routinely dispensed from the corner drug-

store. A four-dose cancer treatment can cost

$120,000. “This is the niche of specialty

pharmacies,” says Eldon Edge, R.Ph., interim

director of Pharmacy at Spectrum Health in

Grand Rapids. “If you have a dose of a drug

that costs thousands of dollars, you don’t

want somebody preparing it wrong, mixing it

wrong, dropping it. You want that very closely

managed. You also want the pharmacy that’s

dispensing it to understand all of the rami-

fications of the drug’s administration. They

have to be very involved.”

Diplomat coaches patients on how to rec-

ognize and manage side effects, such as Hand-

Foot Syndrome, a rash related to certain cancer

therapies like Xeloda. The rash indicates that

the drug is working, but it is often so severe

that patients must be taken off therapy. “If we

can coach the patients on how to manage the

rash, then they don’t have to stop the therapy

and they have a much higher level of success,”

says Hagerman. Diplomat also produces

compliance packaging for complicated HIV/

AIDS therapies that simplify dosage and

dispensing regimens and can increase the

drugs’ effectiveness.

In 2010, Diplomat acquired 550,000 sq.

ft. of space in the former General Motors

Great Lakes Technology Centre in Flint, and

announced plans to hire up to 1,000 new

employees. “We’ve dramatically expanded

our Michigan capabilities,” Hagerman says.

“Moving forward, 75 percent of our services

will be managed and dispensed from our

location in Genesee County. This building

will allow us to grow and expand over the

next ten years.”

“If the doctor asked me to carry a product that was com-plicated and expensive, I just simply found a way to do it.”

“If you have a dose of a drug that costs thousands of dollars, you don’t want somebody pre-paring it wrong, mixing it wrong, dropping it. You want that very closely managed.”

headquartered in flint, Mi, diploMat iS the largeSt privately held Specialty pharMacy in the u.S.

phil hagerMan, preSident and ceo of diploMat pharMacy, haS built a SucceSSful pharMa buSineSS by being a probleM Solver.


records for Ash Stevens. The privately held company’s revenue

grew from $13.5 million in 2008 to $23.4 million in 2010.

“Our strengths are technical and regulatory competence

coupled with a very good system of project management,” says

Munk. “Worldwide, we have…three thousand competitors. Since

January 2003, the FDA has approved around 100 new chemical

entities for the world. We make three of those right here in

Michigan, and typically those products are sole-sourced. We’ve

had 11 FDA approvals in our corporate history. That tells you

we really are competent scientists, and we have the regulatory

piece under control.”

The three API’s for which Ash Stevens received government

approval - azacitidine (Vidaza), bortezomib (Velcade), and clo-

farabine (Clolar) - all benefited from the firm’s fast track program

that helps drug companies navigate the FDA’s approval labyrinth

and get their products into the market faster.

Munk attributes the success of Ash Stevens’ fast track

process to a well-developed project management approach

and a very good understanding of the regulatory requirements.

“There’s a lot of ‘i’s’ to be dotted and ‘t’s’ to be crossed,” he

says. “Not only do you have to develop and validate a robust,

repeatable and consistent chemical process to make the drug,

you have to develop very accurate, precise and repeatable

analytical procedures to demonstrate that the active ingredient

and the drug product are stable. There are a huge number of

things that have to get done to get a drug approved, and we’re

good at that.”

Ash Stevens has approximately 30 clients and 20-30

development projects at various stages, from toxicology to

Phase III clinical trials. To support this activity, and prepare

for future growth, the company announced in 2010 a

five-year, $20 million expansion to its manufacturing facility

in Riverview, Michigan. That facility currently houses the bulk

of the company’s 70 employees, including analytical and

synthesis chemists, manufacturing, engineering, and regulatory

specialists, and laboratories for drug development, production

and quality control.

The new addition includes a 10,000-sq. ft. storage and materials

handling facility and a new reactor bay to accommodate large-

scale API manufacturing. The expansion is expected to create

62 direct jobs and 142 indirect jobs. Munk says the company

will close its office and laboratory complex in Detroit in several

years and consolidate its operations in Riverview.

PROFILE

Ash Stevens Builds on Strengths...and Wins!

under the watch of dr. Stephen Munk, aSh StevenS preSident and ceo, the coMpany’S revenueS juMped 73.3 percent between 2008 and 2010.

As biotech and pharmaceutical companies adapt themselves to

new industry realities that force them to focus on their strengths

and off-load non-core responsibilities, they are increasingly turning

to companies like Ash Stevens to fill the gaps in their expertise.

Founded in Detroit in 1962 by Dr. Arthur Ash, who wrote Wayne

State University’s first Ph.D. dissertation in chemistry, and Wayne

State professor Calvin Stevens, the company’s initial strategy was

to provide contract research services to Walter Reed Army Hos-

pital, the National Institutes of Health, and the National Cancer

Institute. Today, Ash Stevens still has research programs funded

by the NIH, but its major focus lies in developing, registering, and

manufacturing active pharmaceutical ingredients, or API’s, for

clients in the life sciences industry.

“A lot of people are good at discovering things and selling things,

and they can manage the development process, but there are a lot

of very specialized things that go on in [that process] like chemical

development, which is what we do,” says Dr. Stephen Munk, Ash

Stevens’ president and CEO. “We make commercial quantities of

the active pharmaceutical, the business end of the drug.”

The Food and Drug Administration (FDA) has approved an

average of 23 new drugs per year since 2001. This activity, along

with growing demand for contract manufacturers that can safely

and reliably work with highly potent API’s, has resulted in sales

by Tom Beaman

“Since January 2003, the FDA has approved around 100 new chemical entities for the world. We make three of those right here in Michigan.”

Munk attributes the success of Ash Stevens’ fast track process to a well-developed project management approach and a very good under-standing of the regulatory requirements

BioMatters | Fall 201029

ENTREPRENEURS

AFTER THE

Elevator Speech

by Tom Beaman

This issue of BioMatters has already taken a look at the myriad services available to help Michigan bio-entrepreneurs evolve products from “Mind to Market” (see story page 18).

Here is a snapshot of five up-and-comers whose product ideas are marching down the path toward marketability and profit.


ALPHACORE PHARMA, LLC Pharma giant Pfizer shocked Michigan’s economy when it closed three facilities in 2007, eliminating over 2,000 jobs. But Pfizer’s move had a silver lining: it freed up hundreds of experienced scientists like Reyn Homan, Bruce Auerbach, and Brian Krause to pursue their own entrepreneurial dreams. Just months after learning their jobs were disappearing, Homan and his colleagues filed papers to launch AlphaCore Pharma, LLC in Ann Arbor. In August 2008, Homan’s team licensed a patent from the National Institutes of Health’s Office of Technology Transfer that matched their expertise and had commercial potential — the use of a natural protein, lecithin-cholesterol acyltransferase (LCAT), to treat heart disease.

LCAT could also be used in enzyme replace-ment therapy for people who lack sufficient quantities of the protein naturally and often lose kidney function at a young age as a result. AlphaCore is using a Federal Small Busi-ness Innovation Research (SBIR) grant and funds from other investors to take the project through Phase I clinical trial. At press time, Homan’s team was preparing to submit an Investigational New Drug (IND) application to the Food and Drug Administration (FDA). “We hope to get into clinical testing in humans by mid-year,” he says.

TANGENT MEDICAL TECHNOLOGIES, INC. Tangent Medical Technologies, Inc. of Ann Arbor plans to inject itself into the medical device market with a new take on one of the most basic pieces of hospital equipment — the intravenous catheter. Elyse Kemmerer, Ph.D., Tangent’s co-founder and director of business development, says she learned about the need for an improved IV cath-eter after spending a year embedded throughout the University of Michigan Hospital as part of the university’s post-grad Medical Innovation Center (MIC) fellowship program. “We learned that many IV complications are due to micromovement of the catheter inside the vein,” Kemmerer says. “If you control the micromovement, you can extend the dwell time of the IV.”

Kemmerer and three colleagues from the fellowship program with engineering, medical, and business expertise formed Tangent Medi-cal Technologies, Inc. in 2009. Initial funding came from angel investors, a Federal grant, and matching dollars from Ann Arbor SPARK and Michigan’s Automation Alley technology business association. Tangent must still secure FDA approval for the NovaCath device, name a distribution partner, and pass muster with hospitals’ value analysis committees. But Kemmerer has high hopes that the device’s benefits and value will attract a market. “If we’re able to show hospi-tals that our device extends dwell times, that means they can spend less money on supplies, and patients will be more comfortable and will have fewer complications,” she says.

ENTREPRENEURS

“LCAT is an enzyme that circu-lates in everybody’s blood stream and helps make HDL, or ‘good’ cholesterol. The drug would be used for heart attack patients to greatly reduce their risk of having a second one.”

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The company’s NovaCath IV device attaches more securely to the skin, reduces complex tubing, and better protects health care workers from exposure to bodily fluids.

brian krauSe, cSo, and nadia eSMaeil analyze protein SaMpleS at alphacore.

adrienne harriS (l), elySe keMMerer, and Steve white with their prototype novacath iv at tangent Medical.


GENEMARKERS, LLC Genemarkers, LLC opened its doors in Kalamazoo in 2009, and it is already making an impact in the genomic services industry. With only three full-time employees and a stable of contract consultants, Genemarkers has clients in academia and the pharmaceutical, biotech, and personal care industries. Revenue doubled from 2009 to 2010 and is expected to double again in 2011, says Anna Langerveld, Ph.D., Genemarkers owner and president. “Our goal is to assist scientists and industry professionals in incorporating state-of-the-art genomics technologies into their R&D pro-grams,” says Langerveld.

Genemarkers helps clients in the personal care industry understand how skin reacts on a molecular level to environmental conditions, and to validate the efficacy and substantiate claims for sunscreens and anti-aging products. The company also studies genetic “signposts” of nutraceuticals — antioxidant-rich blue-berries, — for their effect on cells, tissues, and diseases. Langerveld believes Genemarkers, which is pursuing Federal Clinical Laboratory Improve-ment Amendments (CLIA) certification, will be well positioned to respond to the demand for genomics expertise from the Kalamazoo life science community and the Western Michigan University medical school that is scheduled to open in 2014. “CLIA certification would enable Genemarkers to support clinical trials and biomarker discovery projects,” she says.

INTERVENTION INSIGHTS The average community oncologist in the U.S. sees over 400 patients a year during 5,100 individual visits. But at only 10-15 minutes per visit, doctors have precious little time to determine a treatment plan for their patients, and may rely only on 10-20 standard-of-care therapies. OncInsight, an interactive information service offered by Grand Rapids start-up Intervention Insights, targets community oncologists who may not have access to the resources of an academic center. OncInsight makes available to doctors a much wider array of treatment options by matching the characteristics of a patient’s tumor (54,000 molecular data points, 22,000 genes) with therapies known to target the tumor’s unique molecular make-up. “We align the knowledge of 305 drugs against the molecular profile of the patient’s disease to find what drugs make the most evidence-based sense for that patient,” says Jerry Callahan, vice president of business development at the Van Andel Institute and chairman of Intervention Insights.

With $3 million of initial investment, Intervention Insights began to serve clients in 2010, using the XenoBase bioinformat-ics platform developed by the Van Andel Institute to sift through mountains of data to detect patterns and trends. Callahan expects a current round of fundraising to fetch another $7 million by year-end.

DELPHINUS MEDICAL TECHNOLOGIES, INC. “Delphinus” is the Latin word for dolphin, which communicates with the aid of under-water acoustic signals. Delphinus Medical Technologies, Inc. of Plymouth, MI is a small company with big plans to revolutionize breast cancer screening, also using properties of sound. Delphinus, which was launched in May 2010 as a spin-off of the Barbara Ann Karmanos Cancer Center, says its SoftVue imaging system is a safe and comfortable alternative to current methods of screening for breast cancer, assessing breast cancer risk, and diagnosing breast diseases.

“We believe the product has substantial advantages over mammography,” says Wil-liam C. Greenway, CEO of Delphinus Medical Technologies. “Traditional ultrasound can see masses quite well, but it can’t really interrogate those masses. Our technology...or density, which is highly correlated to whether or not the tissue is cancerous.” Early clinical trials have shown SoftVue to have a positive predictive value of over 80 percent compared to 50-60 percent for mammography and ultrasound. The first commercial-ready SoftVue unit is scheduled to reach clinical research partners in early 2012. Greenway’s goal is to ultimately capture 15-20 percent of the multi-billion

dollar global breast imaging market.

“We present all the informa-tion that’s relevant within that patient’s tumor and all the aligned drugs in the public literature so the doctor can say, ‘I’m comfortable giving this patient this drug.’”

Combining ultrasound technology and computer algorithms, SoftVue produces a three-dimensional reconstr-uction of the breast while it is submerged in warm water and surrounded by a transducer array ring. The need for radiation or uncomfortable compressing is eliminated.

“We can test any kind of tissue sample or cell type to help sponsors determine which genes are turned on or off by a given condition.”

affyMetrix MicroarrayS uSed for high-throughput gene expreSSion profiling at geneMarkerS.

oncologiStS uSe intervention inSightS’ oncinSight Service to tailor cancer treatMentS for individual patientS.

the delphinuS Softvue breaSt iMaging device differentiateS benign froM Malignant MaSSeS with a Safe, coMfortable and reliable ultraSound technology.


The strength of any industry is in its people, and Michigan’s

bioscience industry is no exception. Thanks in large part to the

comprehensive academic and professional development programs

throughout the state’s universities, research institutes, and commu-

nity colleges, a highly educated and skilled workforce continues to

develop to support the growing bioscience sector.

The University Research Corridor (URC), an alliance of Michigan’s

three largest academic institutions (Michigan State University, the

University of Michigan, and Wayne State University), is collectively

responsible for more than 95% of research generated in the state and

offers a wide range of education and outreach programs in the life

sciences. According to the URC, Michigan’s research universities

award more than 2,600 M.D. and advanced bio-science degrees each

year and conduct more than $1 billion in life science R&D.

The University of Michigan is home to the Life Sciences Institute

(LSI), where “an important part of our mission is to educate and train

students who will go on in the biosciences in Michigan or elsewhere,”

according to Liz Barry, LSI’s managing director.

More than 100 undergraduate and graduate students experience

interdisciplinary research opportunities at LSI under faculty repre-

senting fields such as cell and developmental biology, human genetics,

physiology, bioinformatics, public health, and more. Through LSI’s

Center for Chemical Genomics, students can even gain exposure to

the early stage drug discovery process, conducting the kind of high-

throughput screening that until recently was done only by industry.

Each summer, LSI offers Perrigo Undergraduate Fellowships to

6-8 students from colleges and universities around the state. This

innovative program is funded by the Perrigo Company, a major

manufacturer of generic over-the-counter drugs based in Allegan,

and aims to cultivate and retain Michigan’s top scientific talent. For

10 weeks, fellowship students are mentored by, and work in labs with,

some of LSI’s 400 scientific staff members. To date, nearly 40 students

by David Bardallis

A Strong Pipeline Feeds Michigan’s Wealth of Bio Talent

WORKFORCE DEVELOPMENT

According to the URC, Michigan’s research universities award more than 2,600 M.D. and advanced bio-science degrees each year and conduct more than $1 billion in life science R&D.


have completed fellowships and gone on to

pursuits in pharmacology, emergency medicine,

dentistry, and other bioscience fields.

“LSI is an attractive place for students

because our faculty is at the top of their fields,”

says Barry. “With the open and collaborative

atmosphere here, students often end up work-

ing with several faculty labs from different

fields – it’s good preparation for working in

the bioscience industry, where they will have to

work in multidisciplinary teams.”

BIO-EDUCATION AT SMALLER STATE COLLEGES Michigan Technological University (MTU),

in Houghton, also takes an interdisciplinary

approach through its Biotechnology Research

Center (BRC), where more than 90 graduate

students are conducting hands-on research

in fields including biomedical engineering,

pharmaceutical chemistry, exercise science,

and forest molecular genetics. The center’s 37

faculty members mentor and encourage nearly

100 undergraduates.

“The goal of the center is to bring fac-

ulty and students together from the different

departments and push the envelope in terms

of integrated approaches to the biosciences,”

says Jason Carter, chair of MTU’s department of

exercise science, health, and physical education.

Although traditionally known as an engineering

college, MTU’s commitment to biotechnology

research fits in well with its mission of providing a

solid technological grounding for students, accord-

ing to Carter, and its programs continue to grow.

“We’ve added eight faculty members in just

the past two years as part of our health sciences

initiative,” says Carter. “It’s at the point now

where we’re talking about creating a separate

institute out of the BRC.

“In Michigan, the auto industry has always

dominated, but we’ve amassed a nice piece

of the biotechnology sector,” he adds. “If we

want Michigan to grow in dynamic areas,

biotechnology is a great opportunity.”

Ferris State University in Big Rapids has

offered a four-year biotechnology degree since

1988, but has kept the program small – around

50 students – intentionally.

“Not being one of the big three research

schools in the state, we do have the ability to

offer smaller class sizes, smaller lab sizes, and

a more focused environment,” says Bradley

Isler, assistant professor of biology and coor-

dinator of Ferris’s biotechnology program.

But smaller doesn’t mean second-rate.

Ferris’s biotechnology degree includes two

years in the biology program followed by a

third and fourth year of core biotech courses

taught at a graduate level, including microbiol-

ogy and immunology, biochemistry, molecular

genetics, and bioinformatics. Students also

gain hands-on laboratory experience and

have opportunities for internships in academia,

government research agencies, or firms includ-

ing Neogen in Lansing, Amway (Nutrilite) in

Grand Rapids, and biotech startups in Ann

Arbor and other Michigan cities.

Ferris’s program has been successfully

graduating students with a sound foundation

in the biosciences and a desire to continue their

academic or professional careers in Michigan.

“Our students and grads are incredibly

prepared – employers say they match up favorably

with those from larger, more well-known schools,”

says Isler. “Our students are 50-50 on going on to

grad school or joining the workforce, but the over-

whelming majority of them want to stay in-state.”

THE VAN ANDEL INSTITUTE: TEACHING THE SCIENTISTS OF TOMORROW – AND TODAY Four-year state universities are not the only

institutions providing bioscience education in

the state. The non-profit Van Andel Institute

in Grand Rapids offers a vast array of educa-

tional initiatives and opportunities that run

the gamut from the elementary to postdoctoral

levels through its Van Andel Education Institute

(VAEI) and Van Andel Research Institute (VARI).

VAEI’s Science Academy sponsors programs

that teach elementary and middle school

students to “think and act like scientists” as well

as provide their teachers with professional devel-

opment opportunities. Through the academy’s

Partners for Sustainable Innovation, teachers,

business leaders, and VAEI researchers meet to

learn how curricula can be improved to reflect

the realities of today’s bioscience industry.

For high school students, the Grand Rapids

Area Pre-College Engineering Program is an

opportunity to work in a laboratory while learn-

ing research methods and workplace skills.

“Our philosophy is that youngsters will be

inspired to pursue science-related careers if we let

them do science, not just learn about science,” says

VAEI Director Steven Triezenberg. “The payoff will

have tremendous benefit to their own lives and

to the roles they will play in society, even if those

roles ultimately are not in science-related careers.”

VARI’s programs focus on internships and

opportunities for college students from the

undergrad to grad levels. For the latter, the

VAI Graduate School offers a Ph.D. program

that teaches core concepts in biochemistry,

cell biology, genetics, bioinformatics, and

pathophysiology in preparation for a career in

disease research. Postdoctoral fellowships at

VARI are also available for scientists just starting

their research careers.

“In Michigan, the auto indus-try has always dominated, but we’ve amassed a nice piece of the biotechnology sector...”

“Our students are 50-50 on going on to grad school or joining the workforce, but the overwhelming majority of them want to stay in-state.”

an undergraduate fellowShip prograM at the univerSity of Michigan’S life Science inStitute iS funded by genericS giant, perrigo.

30BioMatters | Fall 2010


Incentives Matter: Economic Development Agencies Work to Attract and Retain Bioscience Jobs and Talent

A welcoming economic environment

is one of the keys to fostering a vibrant

workforce and business climate in Michigan.

Economic development organizations at the

state, regional, and local levels all play a

role in attracting and retaining companies,

jobs, and talent in the biosciences and other

emerging technological industries, enabling

Michigan to boast the fourth-largest high-

tech workforce in the nation.

At the state government level, the Michigan Economic Development

Corporation (MEDC) is working to link companies interested in locating

to or remaining in Michigan with local resources that can help them

succeed even amidst the current challenging economic conditions.

According to Amy Cell, MEDC’s senior vice president for talent en-

hancement, “We provide a suite of programs to help attract, develop,

and retain businesses and workers who contribute to Michigan’s ever-

growing technological sector.”

For example, the MEDC organizes regional job fairs and operates

MichAgain.org, a website aimed at expatriated Michigan professionals

that showcases the opportunities available for those wishing to come

back and continue their careers in the mitten state. The site includes

events and job portals that connect qualified job-seeking candidates

with employers at a roughly 70 percent success rate.

The MEDC also sponsors “Shifting Gears,” a transition program

aimed at corporate professionals who want to retool their skill sets

and pursue new opportunities in growing business sectors — such as

biotechnology — outside of their existing career paths. Eighty percent

of participants successfully land jobs in their new fields within a year.

“The future in Michigan is great,” adds Cell. “We have a fabulous

workforce and the state is committed to bringing companies here and

supporting them through our programs in talent attraction and devel-

opment as well as a good tax structure and a commitment to making

Michigan as business friendly a climate as possible.”

At TechTown, the 43-acre research and technology park located

in Detroit (see story page 19), companies have access to THRIVE, a

program that assists targeted tech startups at critical stages in their

development, from feasibility studies to fundraising strategies to

business launch. With funding from the New Economy Initiative,

a consortium of philanthropic foundations, TechTown is also part of

a three-year, $9.25 million program to provide even more training

and resources to Detroit-area entrepreneurs.

Just north of Detroit, Oakland County offers a range of initia-

tives designed to expand and diversify the local economy, making

the county a true high-tech hub. Its Emerging Sectors initiative, for

example, has helped recruit or retain roughly 70 companies in such

areas as medical device manufacturing, robotics, nanotechnology, and

information technology through tax incentives, financing, site loca-

tion assistance, and more. Started in 2008, “Medical Main Street,”

an alliance of area hospitals, universities, healthcare businesses, and

medical professionals, has helped generate $60 million in investment

and over 1,300 new jobs, according to Irene Spanos, senior business

development representative for the county. All told, Oakland County

boasts more than 4,300 life science and medical facilities with more

than 93,000 jobs in the sector, she said.

MEDC is working to link companies interested in locating to or remaining in Michigan with local resources that can help them succeed even amidst the current challenging economic conditions.

“We have a fabulous workforce and the state is committed to bringing companies here and supporting them through our programs in talent attraction and development.”

“From nanomaterials to stem cell therapiesto cures for diseases like childhood diabetes, I believe we’re going to see some amazing technologies coming out of Oakland County and Metro Detroit in the years ahead.”

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“From nanomaterials to stem cell therapies to cures for

diseases like childhood diabetes, I believe we’re going to see

some amazing technologies coming out of Oakland County and

Metro Detroit in the years ahead,” says Spanos.

On the west side of the state, Kalamazoo’s Southwest

Michigan First (SWMF) pursues an “integrated” model of economic

development, according to CEO Ron Kitchens, bringing together

educational, philanthropic, and business programs and organiza-

tions to create what he calls “community capitalism” in a talent-

rich region shaken up by years of big pharma mergers and layoffs.

For example, SWMF partners with the Monroe-Brown Founda-

tion to sponsor the state’s largest internship program geared to-

ward retaining college students, 75 percent of whom do stay and

work in Michigan after graduation. Through its Life Science Fund

and other capital initiatives, SWMF has also invested more than

$150 million in roughly 70 companies, resulting in the creation of

4,000 new jobs.

“Nobody would intentionally have the ‘creative destruction’

we’ve seen, but now we have a more diversified workforce and

economy and all the new companies are thriving on the talent

available here,” says Kitchens. “It’s really an illustration of

our motto that the best social program in the world is a well

paying job.”

COMMUNITY COLLEGES: PARTNERS IN WORKFORCE DEVELOPMENT Many research lab and production jobs can be done by associate-

level technicians, and several Michigan community colleges offer this

kind of training, as well as associate’s degree and certification programs

for students and professionals who want to enhance or update their job

skills. For example, Kalamazoo Community College and Schoolcraft

College offer programs in biotech skill development, while Lansing,

Oakland, and Henry Ford community colleges offer associate’s degree

programs in molecular biotechnology.

Henry Ford, in fact, offers a number of options – developed in

consultation with area industry leaders – for traditional students and

those seeking professional development.

“About half of our students already have a degree and are coming

for retraining or updating of their skills,” says Charles Jacobs, Ph.D.,

associate dean of science.

Two associate’s degree programs in pre-professional biology and

pre-pharmacy each have about 300 students, many of whom transfer to

four-year schools and grad programs. In addition, Henry Ford offers a

certificate program for already-degreed individuals studying to become

molecular biotechnology technicians; courses in workplace skills, nucleic

acids and proteins, and laboratory instrumentation prepare them for a range

of positions. Optionally, students seeking an associate’s in biotechnology

receive the certification training plus take courses in statistics, ethics,

chemistry, and molecular and cellular biology and complete an internship.

“Michigan, and Southeast Michigan in particular, with its major

universities and colleges, produces a great number of highly competent

bachelor’s, master’s, and Ph.D. scientists,” says Jacobs. “With the addition

of biotech technician programs such as ours, we’re providing the whole

range of workers necessary for a successful biotechnology industry.”

BioMatters | Fall 2010

SWMF partners with the Monroe-Brown Foundation to sponsor the state’s largest internship program geared toward retaining college students, 75 percent of whom do stay and work in Michigan after graduation.

“It’s really an illustration of our motto that the best social program in the world is a well paying job.”

about half of henry ford coMMunity college StudentS attend claSSeS for retraining and SkillS updating. biotechnology certification prograMS and aSSociateS degreeS are offered at a nuMber of Michigan coMMunity collegeS.

“Our philosophy is that youngsters will be inspired to pursue science-related careers if we let them do science, not just learn about science...”


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The Bio-Industry — An Indisputable and Essential Economic Driver for MichiganBy State Senators Tanya Schuitmaker and Rebekah Warren; State Representatives Gail Haines and Roy Schmidt Co-Chairs, Biosciences Legislative Caucus The biosciences industry in Michigan is “big business”. Over 37,000 direct jobs and

a total employment impact of approximately 140,000 translates into $9.5 billion to the

state’s GDP, $2.5 billion in private payroll and over $500,000 million in tax revenues.

Michigan is home to the pharmaceutical giant, Pfizer, large medical device manufacturers

such as Stryker and Terumo, the world’s largest manufacturer of store-brand OTC drugs,

Perrigo, and other industry leaders like Neogen, Emergent Biosolutions, Amway, Kellogg,

and Dow Chemical. The state’s over 550 bio-companies represent a diverse set of industry

subsectors including ag-bio, industrial biotech and chemicals, pharmaceuticals, medical

devices, diagnostics, research products, medical and laboratory testing, informatics and

clinical trials research. All this, coupled with great academic research centers at universi-

ties like Michigan, Michigan State, Wayne State, Oakland, Western Michigan and Michigan

Tech, and eight other such public schools, as well as a host of private higher education and

research institutions, like the Van Andel Institute, and a significant network of community

colleges that host bioscience training programs, reflects Michigan’s commitment to our

bio-industry.

It is essential that Michigan keep its focus on efforts to grow and sustain bioscience

industry development. The biosciences continue to be a high-growth, high-value sector.

Michigan invested approximately $325 million of its former Life Sciences Corridor Fund

and current 21st Century Jobs Fund into the biosciences sector over the last decade in

support of emerging bio-company growth. In addition, our Michigan Venture Fund I,

and recently launched Fund II, along with the Michigan Angel Investor Tax Credit and

Pre-Seed Capital Fund, are state initiatives implemented to spur entrepreneurial ventures

and commercialization of novel bioscience discoveries into real healthcare treatments.

Michigan’s Biosciences Legislative Caucus (BLC) understands the new global dynamic

of increased competition for developing the biosciences industry. We are working actively to

promote and grow the industry within the state. The Michigan BLC recognizes informative

and inclusive discourse as a tool to formulate potential legislative initiatives. By allowing

the biosciences community to integrate with the legislative process we can collectively

impact policies and programs, and help make the state a leader in the global bio-economy.

Our partners in MichBio have been a great resource for the Caucus. They played a

significant role in the formation of legislative committees exclusively focused on the

bio-industry in both the State House and Senate, the first and only state to do so. Moreover,

MichBio helped gather testimony from industry leaders at committee hearings and

compiled it into a Biosciences Action Plan for state legislators to better understand the

needs, challenges and opportunities for Michigan’s bio-industry.

The time for action is now and the Michigan Biosciences Legislative Caucus is

committed to working with our legislative colleagues, biosciences community and

economic development groups to insure that the bio-industry remains a key driver for

the state’s economy, now and well into the future.

G U E S T O P I N I O N

tanya SchuitMaker rebekah warren gail haineS roy SchMidt


MichBio is pleased to provide the 2011 Michigan Biosciences Directory and Resource Guide, the most comprehensive listing of the state’s biosciences companies and organizations.

The complete directory, which includes the information here plus company contacts, email addresses, profiles, and listings by sector and county, is available at www.michbio.org.

Please Note: Information contained in the Michigan Biosciences Directory and Resource Guide is as current as possible. All attempts were made to validate information submitted by companies and to update existing records in MichBio’s database. If your company or organization is not listed, and you believe it should be, please visit the MichBio website (www.michbio.org) and register your company. Direct questions to MichBio to [email protected] or 734.527.9150.

2011 DIRECTORY and RESOURCE GUIDE

BioMattersJ U N E 2 011

MichiganBiosciences


CENTERS OF ExCELLENCEBiosciences research and Commer-cialization Center of Western Michigan

University is a commercially focused and

science driven translational research center

that dedicates its pharmaceutical expertise

and resources to the commercialization of

promising bioscience discoveries and the

growth of Michigan’s bioscience business

sector.

www.brcc.wmich.edu

(269) 544-1072

Michigan animal Models Consortium (MaMC) provides services associated with

the development, analysis and maintenance

of mouse models of human disease. The

consortium combines the technological,

IP expertise and facility resources at the

AAALAC-accredited Van Andel Institute

(VAI). The MAMC provides efficient and

cost-effective animal modeling services.

www.via.org/Research/Services/mamc.aspx

(616) 234-5684

Michigan antibody technologies Center (MatC) consists of the Monoclonal

Antibody Technology Core at the VAI and

the Hybridoma Core at the University of

Michigan (U-M). The MATC has extensive

capabilities in the generation, characteriza-

tion, scale-up and purification of mAbs and

fragments.

www.vai.org/Research/Labs/AntibodyTech-

nology.aspx

(616) 234-5342

Michigan economic Development Corporation (MeDC) is the state’s one-

stop resource for businesses seeking to grow

in Michigan. Created through cooperation

between state and local governments, the

MEDC works with local communities and

businesses to retain and expand job op-

portunities and improve Michigan’s overall

business climate.

www.michiganadvantage.org

(888) 522-0103

Michigan Small Business & technology Development Center (SBtDC) provides

counseling, training, research and advocacy

for new ventures, existing small businesses

and innovative technology companies. Head-

quartered at Grand Valley State University,

the SBTDC supports 12 regional offices and

over 30 satellite offices in the state.

www.gvsu.edu/misbtdc

(616) 331-7480

New enterprise Forum links entrepreneurs

with management expertise, joint venture

partners, business services, capital, and other

critical resources.

www.newenterpriseforum.org

(734) 665-4433

Small Business association of Michigan

helps Michigan small businesses succeed by

promoting entrepreneurship, leveraging buy-

ing power and engaging in political advocacy.

www.sbam.org

(800) 362-5461

GENERAL RESOURCESMichBio is the statewide association committed

to building Michigan’s biosciences industry into

a strong growth engine for the state’s economy.

Its members are biosciences companies, academic

and research institutions, bioscience service

providers, and manufacturing suppliers,

economic development groups, and other

related organizations. MichBio is dedicated to

fostering their collective impact by connecting

its members with essential resources – goods,

services, educational and networking programs,

policy and legislative advocacy, and partners

that facilitate success.

www.michbio.org

(734) 527-9150

MichBio Career Center is a job bank

resource matching talented life sciences

professionals with fulfilling positions in

the state through an online talent search

mechanism.

www.michbio.org/careers

(734) 527-9150

Great Lakes entrepreneur’s Quest (GLeQ) helps Michigan entrepreneurs build high-growth,

new economy business ideas into successful

ventures by linking them to a statewide network

of resources, expert advice, education and

capital. Twice a year, GLEQ hosts a statewide

business plan competition with cash prizes,

media exposure and business development

services.

www.gleq.org

(734) 527-9151

Abundant Resources Help Ideas Become

Life-Changing Realities


Michigan Biological Imaging Center (MBIC) provides comprehensive scientific/

technical imaging expertise including drug

safety and efficacy data to pharmaceutical

industry clients.

http://homepages.wmich.edu/~eversole

(269) 387-5640

Michigan Center for Bioscience Commercialization (MCBC) is a contract

research and development organization

located at the BRCC. The MCBC provides

scientific, medical and regulatory consulta-

tion to aid in the development and commer-

cialization of pharmaceutical, diagnostic

and medical device discoveries.

www.brcc.wmich.edu

(269) 544-1072

Michigan Center for Structural Biology (MCSB) is designed to provide state-of-the-

art instrumentation and support in the area

of macro-molecular structure/function de-

termination for drug discovery. This includes

x-ray crystallography, NMR spectroscopy,

EPR spectroscopy, single molecular spectros-

copy, protein expression and production and

macromolecular structure, synthesis and

sequencing. The MCSB is partnered with and

utilizes beamline resources at the Argonne

National Labs.

http://mcsb.bch.msu.edu

(517) 355-0199

Michigan high-Throughput Screening Center (MhtSC) is a contract research

facility providing services in assay develop-

ment and optimization and high throughput

screening. Staffed by pharmaceutical industry

scientists with drug discovery and HTS

experience, the MHTSC offers screening of

a 100,000+ compound library for a broad

range of therapeutic targets with the client

retaining IP rights to compounds identified

in the screenings.

http://mhtsc.kvcc.edu

(269) 353-1582

NIh National Center for Integrative Biomedical Informatics (NCIBI)

is one of seven National Centers for Biomedical

Computing (NCBC) within the NIH Road-

map, which is focused on building a universal

computing infrastructure designed to speed

progress in biomedical research.

http://portal.ncibi.org/gateway/index.html

(734) 998-8564

Wayne State university applied Genomic technologies (MCGt) provides

oligonucleotide genechip microarrays, custom

cDNA microarrays, and other genomic tech-

nology services on a fee-basis. State-of-the-

art equipment and a full suite of molecular

genomic tools for processing and analysis

means an integrated offering for gene

expression profiling and HTS data mining.

www.bioinformatics.wayne.edu/MCGT

(313) 577-3555

MICHIGAN-BASED FUNDING SOURCESThe 21st Century Jobs Fund represents

a bold initiative to diversify Michigan’s

economy and stimulate job creation in

emerging technology sectors. After being

introduced by the Governor in 2005, it re-

ceived broad, bi-partisan support in the state

Legislature. Using tobacco settlement dollars,

it has already invested $156 million in over

95 commercialization projects in the life

sciences, advanced manufacturing, alterna-

tive energy, and homeland security/defense

sectors through business plan competitions.

In addition, the 21st Century Jobs Investment

Fund was deployed to invest $109 million in

venture capital and private equity funds. To

date nearly $75 million has been invested and

has attracted significant fund management

activity to Michigan, providing Michigan

entrepreneurs access to more diverse capital.

www.michiganadvantage.org/21

(888) 522-0103

Michigan Pre-Seed Capital Fund

supports high-tech start-up companies as

they near commercial viability by providing

access to early-stage capital to accelerate

company development. These funds extend

the personal investment of entrepreneurs

during the critical stage when they are

developing their businesses to the point of

readiness for outside investment. Information

is available from local SmartZonesSM or

www.AnnArborUSA.org

(734) 761-9317

Venture Michigan Fund is a $95 million

venture capital investment program formed

under the Michigan Early Stage Venture

Investment Act of 2003 to promote Michigan’s

economic health by assisting in the creation

of jobs, new businesses and new industries

within the state. The VMF makes investments

ONLY in venture firms that invest primarily

in Michigan-based early stage companies.

www.venturemichigan.com

(248) 619-1868

Federal Funding Opportunities are listed

in the SSTI Weekly Funding Supplement

offered by the federal government, founda-

tions and other industries.

www.ssti.org/Digest/supplement.htm

(614) 901-1690

D I R E C TO RY & R E S O U R C E G U I D E


MICHIGAN BIO-FOCUSED VENTURE AND ANGEL GROUPSann arbor angels www.annarborangels.org

apjohn Group, LLC www.apjohnventures.com

arboretum Ventures www.arboretumvc.com

Beringea www.beringea.com

BioStar Ventures www.biostarfund.com

Capital Community angels www.capitalcommunityangels.org

Dow Venture Capital www.dow.com/venture

early Stage Partners www.esplp.com

eDF Ventures www.edfvc.com

First angels www.southwestmichiganfirst.com/First_Angels.cfm

Fletcher Spaght Ventures www.fletcherspaght.com/ventures

Grand angels www.grandangels.org

Great Lakes angels www.glangels.org

hopen Life Science Ventures www.hopentherapeutics.com

Michigan accelerator Fund 1 www.maf-1.com

Michigan Venture Capital association www.michiganvca.org

Midwest Venture Partners www.midwestvp.com

North Coast technology Investors www.northcoastvc.com

Plymouth Management Company www.plymouthvc.com

Seneca Partners www.senecapartners.com

Southwest Michigan First Life Science Fund www.southwestmichiganfirst.com

tGap Ventures www.tgapventures.com

triathlon Medical Ventures www.tmvp.com

Venture Investors www.ventureinvestors.com

Wolverine Venture Fund www.zli.bus.umich.edu/wvf

UNIVERSITY RESEARCH AND TECHNOLOGY TRANSFERMichigan Initiative for Innovation and entrepreneurshipThe Michigan Initiative for Innovation &

Entrepreneurship (MIIE) builds on Michigan’s

universities as economic assets by speeding

the commercialization of university research

while promoting a culture of entrepreneurial

risk-taking. The initiative partners Michigan’s

philanthropic resources with university and

private business resources to help launch new

startup companies, and strengthen ties be-

tween small business, industry and academia.

www.pcsum.org/aboutthecouncil/

partnerships/miie

(734) 647-5730

Michigan universities Commercializa-tion Initiative (MuCI) complements

and enhances technology transfer functions

at Michigan academic and research institu-

tions by supporting commercialization of

intellectual property.

www.muci.org

technology transfer Offices: l Central Michigan university www.orsp.cmich.edu

(989) 774-4000

l eastern Michigan university www.ord.emich.edu

(734) 487-3090

l Ferris State university www.ferris.edu

(231) 591-2340

l Grand Valley State university www.gvsu.edu/research_dev

(616) 331-2281

l Lake Superior State university www.lssu.edu/eng/pdc/index.php

(906) 635-2738

l Lawrence technological university www.ltu.edu/entrepreneurship/partner-

ship_opportunities.asp

(248) 204-2310

l Michigan State university www.msu.edu/research/index.html

(517) 355-2186

l Michigan technological university www.admin.mtu.edu

(906) 487-1885

l Northern Michigan university http://webb.nmu.edu/Departments/TOS

(906) 227-1000

l Oakland university www2.oakland.edu/research

(248) 370-2100

l Saginaw Valley State university www.svsu.edu/cbed

(989) 964-4000

l university of Michigan www.techtransfer.umich.edu

(734) 763-0614

l Van andel research Institute www.vai.org

(616) 234-5000

l Wayne State university www.techtransfer.wayne.edu

(313) 483-1345

l Western Michigan university www.brcc.wmich.edu

(269) 544-1072 university research Corridor is an alli-

ance between Michigan’s three major research

universities to transform, strengthen and

diversify the state’s economy. The partners,

Michigan State University, the University of

Michigan and Wayne State University, spark

regional economic development via inven-

tion, innovation and technology transfer,

by educating a work force prepared for the

knowledge economy, and by attracting smart

and talented people to Michigan.

www.urcmich.org

(517) 999-4007



SMARTZONESSM AND BUSINESS ACCELERATORS SmartZonesSM provide distinct geographi-

cal locations where technology-based firms,

entrepreneurs and researchers locate in close

proximity to all of the community assets that

assist in their endeavors. SmartZoneSM tech-

nology clusters promote resource collabora-

tions between universities, industry, research

organizations, government and other

community institutions, growing technology-

based businesses and jobs. New and emerging

businesses in SmartZoneSM technology clusters

are primarily focused on commercializing

ideas, patents and other opportunities sur-

rounding corporate, university or private

research institute R&D efforts.

www.michigan.org/smartzones

l ann arbor/ypsilanti: Ann Arbor SPARK, University of Michigan, Eastern Michigan University 201 S. Division St., Ste. 430 Ann Arbor, MI 48104 (734) 761-9317 www.AnnArborUSA.org Contact: Paul Krutko

l automation alley Lawrence Institute of Technology, Oakland University Automation Alley Technology Center 2675 Bellingham Rd. Troy, MI 48083 (248) 457-3200 www.automationalley.com Contact: Tom Anderson

l Battle Creek unlimited Western Michigan University,

Kellogg Community College

4950 W. Dickman Rd.

Battle Creek, MI 49037

(269) 962-7526

www.bcunlimited.org

Contact: Karl Dehn

l Detroit/Woodward technology Corridor: techtown Wayne State University

440 Burroughs, Entrepreneurial Suite

Detroit, MI 48202

(313) 879-5250

www.techtownwsu.org

Contact: Randal Charlton

l Grand rapids: West Michigan Science & technology Initiative Grand Valley State University,

Van Andel Institute

301 Michigan St. NE, Ste. 536

Grand Rapids, MI 49503

(616) 331-5840

www.wmsti.org

Contact: Rich Cook

l houghton/hancock: Michigan tech enterprise Corporation Michigan Technological University

Advance Technology Development

Complex

101 West Lakeshore Drive

Houghton, MI 49931

(906) 487-7000

www.mtecsmart.com

Contact: Carlton K. Crothers

l Jackson technology Park Baker College, Jackson Community

College, Spring Arbor University

One Jackson Square, Ste. 1100

Jackson, MI 49201

(517) 788-4455

www.enterprisegroup.org

Contact: Scott Fleming

l Kalamazoo: WMu Business technology & research Park Western Michigan University

4717 Campus Drive, #100

Kalamazoo, MI 49008

(269) 353-1823

www.kazoosmic.com

Contact: Robert DeWit

l Lansing/east Lansing: university Corporate research Park 2727 Alliance Dr., Ste. C

Lansing, MI 48910

(517) 432-1753

ucrp.msu.edu

Contact: Rhonda Davis

l Macomb INCubator Oakland University

7205 Sterling Ponds Ct.

Sterling Heights, MI 48312

(586) 463-2542

www4.oakland.edu/macombouinc

Contact: Mary Otto

l Midland: Mt. Pleasant SmartZonetM Satellite MidMichigan Innovation Center

4520 E. Ashman Rd., Ste. M

Midland, MI 48642

(989) 839-2333

www.midmichiganinnovationcenter.org

Contact: Chris Moultrup

l Mt. Pleasant: Center for applied research & technology Central Michigan University

2625 Denison Dr.

Mt. Pleasant, MI 48858

(989) 774-2424

www.cmurc.com

l Muskegon Lakeshore Grand Valley State University

380 W. Western Ave., Ste. 202

Muskegon, MI 49440

(231) 724-6702

www.muskegonareafirst.org

Contact: Ed Garner

lrochester hills: Oakland university INCubator Oakland University Shotwell-Gustafson

Pavilion, Oakland University

2200 N. Squirrel Rd.

Rochester, MI 48309

(248) 648-4800

www.oakland.edu/ouinc

Contact: David Spencer


MichBio MeMBer AnnuAl corporAte SponSor preferred provider

BioMatters | Spring 2011 42BioMatters | Spring 2011

l Sault St. Marie Economic Development Corp.

1301 W. Easterday Ave.

Sault Ste. Marie, MI 49783

(906) 635-2738

www.saultedc.com

Contact: Eric Becks

l Wayne County: Pinnacle aeropark University of Michigan, Wayne State

University, Detroit Metropolitan Airport

600 Randolph St., Third Floor

Detroit, MI 48226

(313) 224-0752

www.waynecounty.com

Contact: Dave Tyler

PRIVATE BIOSCIENCE INCUBATORS/BUSINESS ACCELERATORS l Device and Diagnostic accelerator, LLC 38955 Hills Tech Dr. Farmington Hills, MI 48331 (248) 536-0813 http://lifeline-ventures.com/ Contact: Ken Massey

l Great Lakes Stem Cell Innovation Center TechOne Ste. 520, 440 Burroughs Detroit, MI 48202 (313) 405-7705 www.stemcellcommercializationcenter.org Contact: James Eliason

l Michigan Center for regenerative Medicine 401 W. Morgan Rd.

Ann Arbor, MI 48108

(248) 756-6331

Contact: Jim Richter

l Michigan Life Ventures 3605 Tanglewood Dr. Ann Arbor, MI 48105 (734) 769-5447 Contact: Charles Bisgaier

l Michigan research Institute 401 W. Morgan Rd.

Ann Arbor, MI 48108

(734) 756-6331

www.michresearch.org

Contact: Jim Richter

l Vo2 Ventures 29100 Northwestern Hwy., Ste. 110

Southfield, MI 48034

(248) 358-3956

www.vo2ventures.com

Contact: Greig Davis

SELECTED MICHIGAN COUNTY ECONOMIC DEVELOPMENT ORGANIZATIONSalcona

www.alconacountymi.com

allegan www.allegancounty.org

Bay www.baycounty-mi.gov/EACD/Econom-icDevelopment.aspx

Benzie www.benziecountyedc.com

Berrien www.berriencounty.org

Calhoun www.calhouncountymi.org

Genesee www.thegrcc.org

houghton www.houghtoncounty.net

Ingham www.ingham.org/DV/developm.htm

Ionia www.icea-mi.org

Isabella www.mmdc.org

Jackson www.co.jackson.mi.us

Kalamazoo www.southwestmichiganfirst.com

Kent www.rightplace.org

Leelanau www.leelanau.cc

Lenawee www.lenawee.cc

Livingston www.livingstonedc.com

Manistee www.allianceforeconomicsuccess.com

Marquette www.marquette.org/economic-development

Macomb www.macombcountymi.gov/MCPED

Mason www.masoncountygrowth.com

Midland www.midlandtomorrow.org

Monroe www.monroecountyidc.com

Muskegon www.muskegonareafirst.org

Newaygo www.ncedo.org

Oakland www.oakgov.com/peds

Ontonagon www.ontcoedc.com

Otsego www.otsego.org/econdev.htm

Ottawa www.co.ottawa.mi.us

Saginaw www.saginawfuture.com

Sanilac www.sanilaccounty.org

Schoolcraft www.schoolcraftedc.com

St. Clair www.edascc.com

St. Joseph www.sjcedc.com

traverse Bay www.tcchamber.org

Van Buren www.vbco.org/econdev0003.asp

Washtenaw www.AnnArborUSA.org

Wayne www.waynecounty.com/edge

For a complete list of Michigan economic development organizations, please visit www.ecodevdirectory.com/Michigan.htm




Ag-Bio/induStriAl inforMAtion technology MedicAl device reSeArch & developMent phArMAceuticAlS teSting profeSSionAl ServiceS MAnufActuring SupplierS governMent/non-profit educAtion/clinicAl

For further information, please visit www.michbio.org

MichBio MeMBer AnnuAl corporAte SponSor preferred provider MichBio MeMBer AnnuAl corporAte SponSor preferred provider

43

21st Century Therapeutics, Inc. 52673 Seven Oaks, Ste. 105 Shelby Township, 48316 313 874-4879 N/A

3D Biomatrix, LLC 46701 Commerce Center Dr. Plymouth, 48170 734 233-3078 http://www.3d-biomatrix.com

A.M. Todd 1717 Douglas Ave. Kalamazoo, 49007 269 343-2603 http://www.amtodd.com/flash_content.php

AAPharmaSyn LLC 3985 Research Park Dr. Ann Arbor, 48108 734 213-2123 http://www.aapharmasyn.com

Aastrom Biosciences, Inc. 24 Frank Lloyd Wright Dr., Lobby K Ann Arbor, 48105 734 930-5555 http://www.aastrom.com

Abbott Nutrition 901 North Centerville Rd. Sturgis, 49091 269 651-0787 http://www.abbott.com

Abriiz 425 N. Main St. Ann Arbor, 48104 N/A http://www.abriiz.com

Absolute Laboratories Inc. 240 W. Auburn Rd. Rochester Hills, 48307 877 343-5227 http://www.absolutelabs.net

Access Business Group 7575 Fulton St. East Ada, 49335 616 787-6767 http://www.accessbusinessgroup.com

Access Diagnostics, Inc. 5575 Conner Ave., Ste. 1G Detroit, 48213 313 921-2266 http://www.accessdiagnostics.net

Access Medical LLC 1717 Shaffer St., Kalamazoo, 49048 269 276-0068 http://www.accessmedicaldirect.com #107 North Professional Bldg.

Accord Biomaterials, Inc. 3550 W. Liberty Rd., Ste. 3 Ann Arbor, 48103 734 995-9089 http://www.accordbiomaterials.com

Accumed Systems Inc. 6109 Jackson Rd. Ann Arbor, 48103 734 930-0461 http://www.accumedsystemsinc.com

Accuri Cytometers, Inc. 173 Parkland Plz. Ann Arbor, 48103 734 994-8000 http://www.AccuriCytometers.com

Adamlab, LLC 55 E. Long Lake Rd., Ste. 337 Troy, 48085 248 362-9603 http://www.adamlab.com

Adeona Pharmaceuticals 3930 Varsity Dr. Ann Arbor, 48108 734 332-7800 http://www.adeonapharma.com

ADS Biotechnology 5703 N. Main St., Ste. E Sylvania, OH, 43560 419 570-7303 http://www.adsbiotech.com/?page_id=2

Advanced Photonix Inc. 2925 Boardwalk Ann Arbor, 48104 734 864-5639 http://www.advancedphotonix.com

AEGIS Environments 2205 Ridgewood Dr. Midland, 48642 800 241-9186 http://www.microbeshield.com

AFID Therapeutics Inc 3900 Collins Rd., Ste. 1029 Lansing, 48910 517 336-4641 http://www.afidtherapeutics.com

Agrium, Inc. 2405 Vassar Rd. Reese, 48757 989 752-2138 http://www.agrium.com

AI Medical Devices, Inc. 311 Turner Rd. Williamston, 48895 800 219-9561 http://www.aimedicaldevices.com

Air Force Inc. 933 Butternut Dr. Holland, 49424 616 399-8511 http://www.dentalairforce.com

Akervall Technologies 5643 Plymouth Rd. Ann Arbor, 48105 734 485-2949 http://www.akervalltechnologies.com

Albemarle Corporation 1421 S. Kalamazoo St. South Haven, 49090 269 637-8474 http://www.albemarle.com

Algal Scientific Corporation 46701 Commerce Center Dr. Plymouth, 48170 734 218-5717 http://www.algalscientific.com

Alivio Corporation 20429 Honor Hwy. Interlochen, 49643 231 275-1345 http://www.aliviocorp.com

AlixPartners 2000 Town Center, Ste. 2400 Southfield, 48075 248 358-4420 http://www.alixpartners.com

Alliant Healthcare Products 8850 M-89 Richland, 49083 269 629-0300 http://www.allianthealthcare.com

Alluvium Biosciences 401 W. Morgan Rd. Ann Arbor, 48108 734 276-4921 http://www.alluviumbio.com

AlphaCore Pharma 333 Parkland Plaza, Ste. 5 Ann Arbor, 48103 734 527-9137 N/A

A-L-S Technologies Inc. 1740 W. Big Beaver Troy, 48084 248 885-8302 http://www.als-tech.com

Altarum Institute 3520 Green Ct., Ste. 300 Ann Arbor, 48105 734 302-4600 http://www.altarum.org

Altus Industries 3731 Northridge Dr. NW, Unit 1 Walker, 49544 888 537-1311 http://www.altus-inc.com

American Diabetes Association 30300 Telegraph Rd., Ste. 117 Bingham Farms, 48025 248 433-3830 http://www.diabetes.org

American Seating 401 American Seating Ctr. NW Grand Rapids, 49504 616 732-6600 http://www.americanseating.com

American Society for Microbiology 9205 Huron River Drive. Dexter Township, 48130 734 845-3661 http://www.mi-asm.org

American Society of Employers 23815 Northwestern Hwy. Southfield, 48075 248 223-8019 http://www.aseonline.org

AmFab, Inc. 1446 South 35th St. Galesburg, 49053 269 665-6703 http://www.amfab.com

Amgen 9935 N. Valley Hill Dr. Mequon, WI, 53092 262 240-9961 http://www.amgen.com

Amigo Mobility International, Inc. 6693 Dixie Hwy. Bridgeport, 48722 989 921-5062 http://www.myamigo.com

Angott Medical Products, LLC 442 Five Gaits Ct. Bloomfield Hills, 48304 248 444-1492 N/A

Ann Arbor Clinical Research 203 S. Zeeb Rd., Ste. 105 Ann Arbor, 48103 734 926-0957 http://www.annarborclinicalresearch.com

Ann Arbor SPARK 201 S. Division, Ste. 430 Ann Arbor, 48104 734 761-9317 http://www.AnnArborUSA.org

Antel BioSystems, Inc 3655 Forest Rd. Lansing, 48910 800 631-3510 http://www.antelbio.com






44

Apjohn Group, LLC 350 E. Michigan Ave., Ste. 500 Kalamazoo, 49007 269 349-8999 http://www.apjohngroup.com

ApoLife, Inc. 100 River Pl., #5350 Detroit, 48207 313 446-2625 http://www.apolife.com

AquaBiochip, LLC 1012 N. Walnut St., Ste. 101 Lansing, 48906 517 402-2692 http://www.aquabiochip.com

Arbor Assays LLC 1514 Eisenhower Pl. Ann Arbor, 48108 734 677-1774 http://www.ArborAssays.com

Arbor Preclinical & Consulting, LLC 8975 South Ave. E Scotts, 49088 734 330-4396 http://www.arborpcc.com

Arbor Research Collaborative 315 W. Huron St., Ste. 360 Ann Arbor, 48103 734 665-4108 http://www.arborresearch.org for Health

Arboretum Ventures Market Place Building, Ann Arbor, 48104 734 998-3688 http://www.arboretumvc.com 303 Detroit St., Ste. 301

Arcanum Corporation 5340 Plymouth Dr., Ste. 101 Ann Abor, 48105 734 665-4421 N/A

Arivium, Inc. 1440 Front Ave. NW, Penthouse A Grand Rapids, 49504 616 292-5018 http://www.arivium.com

Armune BioScience, Inc. 350 E. Michigan Ave., Ste. 500 Kalamazoo, 49007 269 349-8870 http://www.armune.com

Art Optical Contact Lens, Inc. 3175 3 Mile Rd. NW Walker, 49534 616 453-1888 http://www.artoptical.com

ArtJen Complexus USA 440 Burroughs St., Mailbox 65 Detroit, 48202 877 4-ARTJEN http://www.mirafit.com

Ascendant MDx, Inc. 26842 Haggerty Rd. Farmington Hills, 48331 N/A N/A

Ash Stevens 5861 John C. Lodge Fwy. Detroit, 48202 313 872-6400 http://www.ashstevens.com

ASI Instruments, Inc. 12900 E. Ten Mile Rd. Warren, 48089 586 756-1222 http://www.asi-instruments.com

Aspen Surgical Products, Inc. 6945 Southbelt SE Caledonia, 49316 888 364-7004 http://www.aspensurgical.com

Asterand Inc. TechOne Bldg, 440 Burroughs, Ste. 501 Detroit, 48202 313 263-0960 http://www.asterand.com

ATEK Medical Manufacturing 620 Watson SW Grand Rapids, 49504 616 643-5200 http://www.atekmedical.com

Ateq Corporation 35980 Industrial Dr. Livonia, 48150 734 838-3100 http://www.atequsa.com

Auburn Pharmaceutical Company 1775 John R. Rd. Troy, 48083 248 526-3750 http://www.auburnpharm.com

AureoGen Biosciences, Inc. 6475 Technology Ave., Ste. C Kalamazoo, 49009 269 353-3805 http://www.aureogen.com

Aursos, Inc 350 E. Michigan Ave., Ste. 500 Kalamazoo, 49007 703 845-5429 http://www.aursos.com

Autocam Medical 4436 Broadmoor SE Kentwood, 49512 616 541-8080 http://www.autocam-medical.com

Automated Software Technology 1328 Ramblewood East Lansing, 48823 517 316-2138 http://www.autosofttech.net

Automation Alley 2675 Bellingham Troy, 48083 248 457-3200 http://www.automationalley.com

AVAcore Technologies 333 Parkland Plaza Dr., Ste. 700 Ann Arbor, 48103 888 282-2673 http://www.avacore.com

Avalon Laboratories LLC 301 Michigan St. NE, Ste. 500 Grand Rapids, 49503 616 331-5843 http://www.avalonlabs.com

Avicenna Medical Systems, Inc. 3090 Dhu Varren Ct. Ann Arbor, 48105 888 284-4080 http://www.avicenna-medical.com

AxioBionics 6111 Jackson Rd., Ste. 200 Ann Arbor, 48103 734 327-2946 http://www.axiobionics.com

Axsys Technologies, Inc. 2909 Waterview Dr. Rochester Hills, 48309 248 293-2900 http://www.axsys.com

Azenic Dental, Inc. 350 E. Michigan Ave., Ste. 135 Kalamazoo, 49007 269 349-8870 http://www.azenic.com

AzoRx, Inc. 4717 Campus Dr. Kalamazoo, 49008 269 760-0403 http://www.azorx.com

BAC Technologies, LLC 540 Avis Dr., Ste. A Ann Arbor, 48103 734 663-4233 http://www.tsrlinc.com

Barbara Ann Karmanos 4100 John R. Rd., Detroit, 48201 800 527-6266 http://www.karmanos.org Cancer Institute

BarbLock 11590 S. US-31 Williamsburg, 49690 231 264-0101 http://www.barblock.com

Bauer Biomedical, LLC 2625 Denison Dr. Mt. Pleasant, 48854 810 397-2882 N/A

Bayer CropScience 1740 N. Whitehall Muskegon, 49445 231 719-3000 http://www.bayercropscience.com

Bayer Health Care 6549 Braemar Ave. Noblesville, IN, 46069 317 774-8069 http://www.bayerhealth.com

BD - Difco Laboratories 920 Henry St. Detroit, 48201 313 442-8000 http://www.bd.com

BD Diagnostics 5230 S. State Rd. Ann Arbor, 48108 734 663-4719 http://www.bd.com

Beaumont Bio Bank Research Institute, 3811 W. 13 Mile Rd. Royal Oak, 48073 248 898-5000 http://www.beaumonthospitals.com/biobank

Beaumont Commercialization Center 3601 W. Thirteen Mile Rd. Royal Oak, 48073 248 551-0255 http://www.beaumontcommercializationcenter.com

Beaumont Hospitals 3601 W. Thirteen Mile Rd. Royal Oak, 48073 248 551-8550 http://www.beaumonthospitals.com

Beaumont Laboratory 3601 W. Thirteen Mile Rd. Royal Oak, 48073 248 551-8550 http://www.beaumonthospitals.com/labs

Becker Orthopedic 635 Executive Dr. Troy, 48083 248 588-7480 http://www.beckerorthopedic.com






45

Beckman Coulter Molecular 22900 W. Eight Mile Rd. Southfield, 48033 248 351-5600 http://www.lumigen.com Diagnostics (aka Lumigen, Inc.)

Berry & Associates, Inc. 2434 Bishop Circle E. Dexter, 48130 734 426-3787 http://www.berryassoc.com

Better Rehab, LLC 1170 Morehead Ct. Ann Arbor, 48104 734 604-1966 N/A

Biddergy.com 1919 E. Kilgore Service Rd. Kalamazoo, 49002 N/A http://www.biddergy.com

Bio Logic Engineering, Inc. 1675 N. Lima Center Rd. Dexter, 48130 248 719-3150 http://www.biologicengineering.com

Bio-Chem Laboratories, Inc. 1049 28th St., SE Grand Rapids, 49508 616 248-4900 http://www.bio-chem.com/Home/tabid/36/Default.aspx

Biogen Inc. 2572 Tibernyck Trail Dr. Troy, 48098 248 646-4791 http://www.biogen.com

Bio-lab, Inc., A Chemtura Company 1400 E. Michigan St. Adrian, 49221 517 265-6138 http://www.chemtura.com

BioLumix, Inc 104 Aprill Dr. Ann Arbor, 48103 734 984-3100 http://www.mybiolumix.com

Biomedical Diagnostics, LLC 5692 Plymouth Rd., Ste. B Ann Arbor, 48105 888 652-4246 http://www.bio-diagnostics.com

BioMedware Inc. 3526 W. Liberty Rd., Ste. 100 Ann Arbor, 48103 734 913-1098 http://www.biomedware.com

Biomide 21 Kercheval Ave., Ste. 330 Grosse Pointe Farms, 48236 313 886-0589 N/A

Bio-Nano Power, LLC 2625 Denison Dr. Mt. Pleasant, 48858 616 682-0367 N/A

Biopelle 780 W. 8 Mile Rd. Ferndale, 48220 866 424-6735 http://www.biopelle.com

BioPharma Data Services 1461 Scio Ridge Ct. Ann Arbor, 48103 734 255-1038 http://www.BioPharmaDataServices.com

Biophotonic Solutions, Inc. 1401 E. Lansing Dr., Ste. 112 East Lansing, 48823 517 580-4075 http://www.biophotonicsolutions.com

Biopolymer Innovations 16647 Chandler Rd. East Lansing, 48823 517 432-3044 http://www.biopolymerinnovations.com

BioPro 2929 Lapeer Rd. Port Huron, 48060 810 982-7777 http://www.bioproimplants.com

Biosciences Research and 4717 Campus Dr. Kalamazoo, 49008 269 544-1072 http://www.brcc.wmich.edu Commercialization Center at Western Michigan University

Biosol, Ltd. 206 Fifth Ave. Ann Arbor, 48104 734 663-0645 http://www.liposol.com

BioSolutions, LLC 1811 Hayes St. #E Grand Haven, 49417 616 846-1210 http://www.biosolutionsllc.com

BioSTAT Consultants, Inc. 528 W. Centre Ave. Portage, 49024 269 329-7976 http://www.biostat.net

Biotech Clinical Laboratories 24469 Indoplex Cir. Farmington Hills, 48335 248 426-9800 http://www.biotechclinical.com

Biotechnology Business 803 N. Main St. Ann Arbor, 48104 734 930-9741 http://www.bioconsultants.com Consultants & BBCetc.

Biotectix 940 N. Main St. Ann Arbor, 48104 734 585-5126 http://www.biotectix.com

Biotronic NeuroNetwork 812 Avis Dr. Ann Arbor, 48108 800 638-7564 http://www.biotronic.com

Birchbrook Technologies L.L.C. 53470 Andrew Cir. New Baltimore, 48047 586 648-8267 http://www.birchtek.com

Blaze Medical Devices 9146 Dexter Pinckney Rd. Pinckney, 48169 734 945-7764 http://www.blazemedicaldevices.com

BlueWare, Inc. 3060 W. 13th St. Cadillac, 49601 231 779-0224 http://www.blueware.net

Borgess Research Institute 1717 Shaffer, Ste. 003 Kalamazoo, 49048 269 226-5407 http://www.research.borgess.com

BoroPharm, Inc. 2800 Plymouth Rd., Bldg. 40 Ann Arbor, 48105 517 455-7847 http://www.boropharm.com

Bremer Prosthetic Design, Inc. 3487 S. Lindin Rd., Ste. U Flint, 48507 810 733-3375 http://www.bremerprosthetics.com

Brenner Orthotic and Prosthetic Labs 32975 W. Eight Mile Rd. Livonia, 48152 810 615-0601 N/A

BREONICS W.A. Harriman Tech. Campus, Bldg 7A Albany, NY, 12206 518 213-4670 http://www.breonics.com

Bridge Organics Co. 311 W. Washington St. Vicksburg, 49097 269 649-4200 http://www.bridgeorganics.com

Brighton Analyticals, LLC 2105 Pless Dr. Brighton, 48114 810 229-7575 http://brightonanalytical.net

Brio Device, LLC 2378 Leslie Cir. Ann Arbor, 48105 734 945-5728 N/A

Brown & Brown of Detroit 35735 Mound Rd. Sterling Heights, 48311 586 977-6300 http://www.bbdetroit.com

Bryllan, LLC 26105 Orchard Lake Rd. Farmington Hills, 48334 248 699-6113 http://www.bryllan.com

Butzel Long 350 S. Main St., Ste. 300 Ann Arbor, 48104 734 213-3435 http://www.butzel.com

Calibrate, Inc. - The Pipet People 3600 Green Ct., Ste. 400 Ann Arbor, 48105 919 240-4089 http://www.pipetpeople.com

Caltech Industries, Inc. 4520 E. Ashman Rd., Ste. C Midland, 48642 989 496-3110 http://www.caltechind.com

Caraco Pharmaceutical 1150 Elijah McCoy Dr. Detroit, 48202 313 871-8400 http://www.caraco.com Laboratories, Ltd.

CardiArc 7444 Haggerty Rd. Canton, 48187 734 738-1963 http://www.cardiarc.com

Cardiavent 3991 Ramsgate Ct. Ann Arbor, 48103 N/A http://www.cardiavent.com






46

Cascade Hemophilia Consortium 210 E. Huron St., Ste. D Ann Arbor, 48104 734 996-3300 http://www.hemoalliance.org

Cascade Life Solutions 3710 Sysco Ct., SE Grand Rapids, 49512 616 977-2515 N/A

Cayman Chemical Company 1180 E. Ellsworth Rd. Ann Arbor, 48108 734 971-3335 http://www.caymanchem.com

CeeTox, Inc. 4717 Campus Dr. Kalamazoo, 49008 269 353-5555 http://www.ceetox.com

Cell Culture Characterization Services 1872 N. Adams Rochester Hills, 48306 248 656-2542 N/A

Cellular Biotechnology 1150 W. Medical Center Dr. Ann Arbor, 48109 734 763-3533 http://www.cbtp.umich.edu Training Program

Center for Clinical Research 8357 Glenwynd Dr. Kalamazoo, 49009 269 375-2915 http://www.c2rs.com Solutions, Inc.

Center for Reproductive 300 Park St., Ste. 460 Birmingham, 48009 248 593-6990 http://reproductive-medicine.com Medicine and Surgery

Central Michigan University Brooks Hall Mt. Pleasant, 48858 989 774-4000 http://www.cmich.edu

Central Michigan University - Center 2625 Denison Dr. Mt. Pleasant, 48858 989 774-1574 http://www.cmich.edu/x793.xml for Applied Research & Technology

Central Michigan University - 4170 S. Meridian Mt. Pleasant, 48858 989 774-4000 http://www.cmich.edu Dow College of Health Professions

Central Michigan University - Office 251 Foust Hall Mt. Pleasant, 48858 989 774-6777 http://www.orsp.cmich.edu of Research and Sponsored Programs

Centurion Medical Products 100 Centurion Way Williamston, 48895 800 248-4058 http://www.centurionmp.com

Cerenis Therapeutics Inc. 900 Victors Way, Ste. 280 Ann Arbor, 48108 734 769-1110 http://www.cerenis.com

Cerise Nutraceuticals, Inc. 1670 Barlow St., Ste. A Traverse City, 49686 231 933-3300 http://www.cherrylotion.com

CFI Medical Solutions 14241 Fenton Rd. Fenton, 48430 810 750-5300 http://www.cfimedical.com (Contour Fabricators, Inc.)

Charles River 9801 Shaver Rd. Portage, 49002 269 327-4248 http://www.criver.com

Chase Environmental Group, Inc. 1835 Timber Tr. Ann Arbor, 48103 734 255-9034 http://www.chaseenv.com

Chelon, Inc. 6450 Bridlewood Ct. Ada, 49301 616 682-0793 N/A

Chemtura 1400 E. Michigan St. Adrian, 49221 517 265-6138 http://www.chemtura.com

Children’s Hospital of Michigan 3901 Beaubien Detroit, 48201 888 362-2500 http://www.childrensdmc.org

Christian Roux Ltd. 598 E. Grand Blvd. Ypsilanti, 48198 734 732-6671 http://www.hurricanecrutch.com

Chubb Group of Insurance Companies 1450 W. Long Lake Rd., Ste. 210 Troy, 48098 734 741-1850 http://www.chubb.com

Cielo MedSolutions 3520 Green Ct., Ste. 200 Ann Arbor, 48105 734 827-1000 http://www.cielomedsolutions.com

City of Marshall Economic 323 W. Michigan Marshall, 49068 269 781-5183 http://www.cityofmarshall.com Development

Clear Image Devices 3930 Michael Rd. N Ann Arbor, 48103 734 645-6459 http://www.clearimagedevices.com

Clinical Ligand Assay Society 29003 Balmoral St. Garden City, 48135 734 722-6290 http://www.clas.org

ClinSite, Inc. 24 Frank Lloyd Wright Dr., Lobby A Ann Arbor, 48106 734 930-3700 http://www.clinsite.com

ClinXus 330 Bostwick Ave., NE Grand Rapids, 49503 616 331-5854 http://www.clinxus.org

CNVGenes LLC 4995 Arrowhead Rd. West Bloomfield, 48323 248 682-3368 http://www.cnvgenes.com

Coherix, Inc. 3980 Ranchero Dr. Ann Arbor, 48108 734 761-8989 http://www.coherix.com

College Park Industries 17505 Helro Rd. Fraser, 48026 586 294-7950 http://www.college-park.com

Compendia Bioscience 110 Miller Ave., Floor 2 Ann Arbor, 48104 734 929-3909 http://www.compendiabio.com

Conceivex 5 E. Main St. Saranac, 48881 888 306-6366 http://www.conceptionkit.com

Concepts in Software 455 Woodland Hills Dr. Walled Lake, 48390 734 730-4692 http://www.conceptsinsoftware.com

Contented Hearts, Inc. 11490 East G Ave. Galesburg, 49053 269 665-4420 http://www.contentedhearts.com

Copagen 5528 Gallery Park Dr. Ann Arbor, 48103 734 904-0365 N/A

Corium International, Inc. 4558 50th St., SE Grand Rapids, 49512 616 656-4563 http://www.coriumintl.com

Covalent Medical, Inc. 4750 S. State St., Ste. 301 Ann Arbor, 48108 734 429-2451 http://www.covamed.com

Covance Research Products 6321 S. 6th St. Kalamazoo, 49009 269 375-0482 http://www.crpinc.com






47

Coy Laboratory Products Inc. 14500 Coy Dr. Grass Lake, 49240 734 475-2200 http://www.coylab.com

CPR Mattress 200 Michigan St. Hancock, 49930 906 483-2676 http://www.cprmattress.com

Crissman Toxicologic Pathology, LLC 2887 Oakhaven Ct. Midland, 48642 989 631-2790 http://www.pathexperts.com

Critech Research, Inc. 1705 Woodland Dr. E., Ste. 100 Saline, 48176 734 668-0005 http://www.critech.com

Critical Signal Technologies 22600 Haggerty Rd. Farmington Hills, 48335 888 557-4462 http://www.criticalsignaltechnologies.com

Custom Biogenic Systems 150 Shafer Dr. Romeo, 48065 586 331-2600 http://www.custombiogenics.com

Cutting Image Histology, LLC 800 Technology Dr. Ann Arbor, 48108 517 712-3102 http://www.cuttingimagehistology.com

Cybernet Medical Cybernet Systems Corporation, Ann Arbor, 48108 800 292-3763 http://www.cybernetmedical.com 727 Airport Blvd.

CytoPherx 401 W. Morgan Rd. Ann Arbor, 48108 734 272-4772 http://www.cytopherx.com

Danmar Products Inc. 221 Jackson Industrial Dr. Ann Arbor, 48103 800 783-1998 http://www.danmarproducts.com

Dast Systems, LLC 270 Chesterfield Birmingham, 48009 N/A N/A

Data Integrated Scientific Systems 8031 Main St., Ste. 301 Dexter, 48130 734 426-4995 http://www.dissdata.com

DataSpeaks, Inc. 2971 Vineyards Dr. Troy, 48098 248 952-1968 http://www.dataspeaks.com

Davis Dental Labs 5830 Crossroad, Commerce Pkwy. Wyoming, 49519 616 261-9191 http://www.dentalservices.net/davis

DavisMade, Inc. 2511 Davison Rd. Flint, 48506 866 742-0581 http://www.standingdani.com

DBA Analytical (an NSF 789 Dixboro Rd. Ann Arbor, 48113 734 769 8010 http://www.dba-global.com International Company)

DDots, Inc. 4571 Ellsworth Rd. Ypsilanti, 48197 734 434-7734 http://www.ddots.com

DeAnza Fuel Group 99 Monroe Grand Rapids, 49503 888 332-0141 http://www.deanzafuel.com/index.htm

Delphinus Medical Technologies Hudson-Webber Cancer Research Center, Detroit, 48201 313 576-8251 http://www.delphinusmt.com Rm. 504, 4100 John R. Rd.

Dendritech, Inc. 3110 Schuette Dr. Midland, 48642 989 496-1152 http://www.dendritech.com

Dendritic Nanotechnologies, Inc. DNT Finance, 2625 Denison Dr. Mt. Pleasant, 48858 989 774-6565 http://www.dnanotech.com

Dermanaut 5260 Anthony Wayne Dr. Detroit, 48202 313 202-6760 http://www.dermanaut.com

Detroit Clinical Research Center 27780 Novi Rd., Stes. 100 & 230 Novi, 48377 248 825-3159 http://www.dcrc.us

Detroit Medical Center-Wayne 4201 Antoine St. Detroit, 48201 313 993-8921 http://www.dmc.org/univlab/default.htm State Lab

Detroit Neurosurgical Foundation 3333 E. Jefferson Ave. Detroit, 48207 313 259-0391 N/A

Detroit R&D, Inc. Metropolitan Center for High Technology Detroit, 48201 313 961-1606 http://www.detroitrandd.com (MCHT), 2727 Second Ave., Ste. 4113

Device and Diagnostic 38955 Hills Tech Dr. Farmington Hills, 48331 248 536-0813 N/A Accelerator, LLC

Diagnostic Instruments Inc. 6540 Burroughs St. Sterling Heights, 48314 586 731-6000 http://www.diaginc.com

Diamond General 333 Parkland Plaza Dr. Ann Arbor, 48103 800 678-9856 http://www.diamondgeneral.com

Digilab Genomic Solutions 4355 Varsity Dr., Ste. E Ann Arbor, 48108 734 975-4800 http://www.genomicsolutions.com

Diversified Natural Products 506 E. State St. Scottville, 49454 231 757-9241 http://www.dnpworld.com

DNA Software, Inc. 334 E. Washington St. Ann Arbor, 48104 734 222-9080 http://www.dnasoftware.com

DNADNB LLC 4995 Arrowhead Rd. West Bloomfield, 48323 248 682-3368 N/A

Doeren Mayhew 755 W. Big Beaver Rd., Ste. 2300 Troy, 48084 248 244-3005 http://www.doeren.com

DRAMgene 39 Blackburn SW Wyoming, 49509 616 828-2207 N/A

Draths Corporation 4055 English Oak Dr. Lansing, 48911 517 349-0669 http://www.drathscorporation.com

Drug & Laboratory Disposal, Inc. 331 Broad St. Plainwell, 49080 269 685-9824 http://www.dld-inc.com

DSC Labs 1979 Latimer Dr. Muskegon, 49442 231 777-3012 http://www.dsclab.com

Ducker Worldwide 1250 Maplelawn Troy, 48084 248 644-0086 http://www.ducker.com

DuPeron Medical Systems 515 N. Washington Ave. Saginaw, 48607 800 383-8479 http://www.duperon.com

Dykema Gossett PLC 400 Renaissance Center Detroit, 48243 313 568-6800 http://www.dykema.com






48

Eastern Michigan University College of Arts & Sciences, Ypsilanti, 48197 734 487-1955 http://www.emich.edu 411 Pray-Harrold

Eastern Michigan University - 559 Owen College of Business Ypsilanti, 48197 734 487-6516 http://www.emich.edu/public/cob/entrepreneur Center for Entrepreneurship

Eastern Michigan University - Starkweather Hall, Office of Ypsilanti, 48197 734 487-3090 http://www.emich.edu Office Research Development Research Development

ECO PHYSICS, INC. 3915 Research Park, Ste. A-3 Ann Arbor, 48108 734 998-1600 http://www.ecophysics-us.com

Ecology Health Products, Inc. 12941 E. Townline Rd. Goetzville, 49736 866 326-7763 http://www.ecologyproducts.com

EcoSynthetix 3900 Collins Rd. Lansing, 48910 517 336-4623 http://www.ecosynthetix.com

Ecotek 440 Burroughs St., Ste. 511 Detroit, 48202 313 399-7893 http://www.ecotek-us.com

EdgeHealth LLC 217 Third St. Ann Arbor, 48103 734 622-8060 N/A

Elan Nutrition Inc. 4490 44th St. SE Grand Rapids, 49512 616 940-6000 http://www.elannutrition.com

Elba Laboratories 1925 W. Maple Rd. Troy, 48084 248 288-6098 http://www.elba-labs.com

Elm Strategies LLC 2300 Melrose Ave. Ann Arbor, 48104 734 604-2479 N/A

Eloquest Healthcare 780 W. Eight Mile Rd. Ferndale, 48220 877 433-7626 http://www.eloquesthealthcare.com

Elsevier 3675 Crestwood Pkwy., Ste. 400 Duluth, GA, 30096 770 935-6077 http://www.elsevier.com

Emerald BioAgriculture Corporation/ 2123 University Park Dr., Ste. 105 Okemos, 48864 517 882-7370 http://www.emeraldbio.com Auxein Corporation

Emergent BioSolutions 3500 Martin Luther King Jr. Blvd. Lansing, 48906 517 327-1500 http://www.ebsi.com

Emiliem 4717 Campus Dr., Ste. 700 Kalamazoo, 49009 415 421-0222 http://www.emiliem.com

Emil’s Molecular Design, LLC. 8772 Trillium Dr. Ypsilanti, 48197 N/A N/A

Endra Inc 35 Research Dr. Ann Arbor, 48103 734 274-2258 http://www.endrainc.com

Ennew Medical Devices, LLC 2400 N. 6th St. Kalamazoo, 49009 269 615-5113 N/A

Enzo Life Sciences International, Inc. 5777 Hines Dr. Ann Arbor, 48108 734 668-6113 http://www.assaydesigns.com (formerly Assay Designs, Inc.)

Epsilon Imaging Inc. 3917 Research Park Dr. Ann Arbor, 48108 734 369-5100 http://www.epsilon-imaging.com

Ernst & Young LLP 171 Monroe Ave. NW Grand Rapids, 49503 313 628-7100 http://www.ey.com

Esperion Therapeutics, Inc. 46701 Commerce Center Dr. Plymouth, 48170 734 862-4840 http://www.esperion.com

Essen BioScience 300 W. Morgan Rd. Ann Arbor, 48108 734 769-1600 http://www.essen-instruments.com

Eurofins Avtech Laboratories, Inc. 6859 Quality Way Portage, 49002 269 323-3366 http://www.eurofins.com

Everist Genomics, Inc. 401 W. Morgan Rd. Ann Arbor, 48108 734 929-9475 http://www.genetics2.com

exCel Cosmeceuticals, Inc. 4120 Maple Rd. Bloomfield Hills, 48301 248 539-1212 http://www.xlafa.com

Exponent, Inc. 39100 Country Club Dr. Farmington Hills, 48331 248 324-9100 http://www.exponent.com

EXT Lifesciences, Inc. 2000 Town Center Southfield, 48075 248 948-6910 http://www.extlifesciences.com

EyeLab Group 2350 Washtenaw Ann Arbor, 48104 734 665-0566 http://www.eyelabgroup.com

e-Zassi 1886 S. 14th St. Amelia Island, FL, 32034 904 261-6290 http://www.e-zassi.com

Ferndale Laboratories Inc. 780 W. Eight Mile Rd. Ferndale, 48220 248 548-2422 http://www.ferndalelabs.com

Ferndale Pharma Group 780 W. Eight Mile Rd. Ferndale, 48220 248 548-0900 http://www.ferndalelabs.com

Ferris State University 1201 S. State St. Big Rapids, 49307 231 591-2000 http://www.ferris.edu

Ferris State University - Biotechnology 820 Campus Dr. / ASC 2004 Big Rapids, 49307 231 591-2641 http://catalog.ferris.edu/programs/26 Program/Department of Biology

Field Neurosciences Institute 4677 Towne Center Saginaw, 48604 989 797-3117 http://www.fni.org

Filtrona Porous Technologies 5301 S. Graham Rd. St. Charles, 48655 800 566-8569 http://www.filtronafibertec.com

FlowSense 1456 Astor Dr. Ann Arbor, 48108 N/A http://www.flowsensemedical.com

FlowTech Corporation 7601 Stadium Dr. Kalamazoo, 49009 269 375-1290 http://www.flowtechfilters.com

Fluid Insights LLC 4995 Arrowhead Rd. West Bloomfield, 48323 248 682-3368 N/A






49

Forensic Fluids Laboratories Inc. 225 Parsons St. Kalamazoo, 49007 269 492-7700 http://www.forensicfluids.com

Fraunhofer USA CCL B100 Eng. Research Complex East Lansing, 48824 517 432-8711 http://www.ccl.fraunhofer.org

Fraunhofer USA, Center for 46025 Port St. Plymouth, 48170 734 354-6300 http://www.clt.fraunhofer.com Laser Technology (CLT)

Freeman Manufacturing Company 900 W. Chicago Rd. Sturgis, 49091 269 651-2371 http://www.freemanmfg.com

Fuller Compliance, LLC 5742 Springwater Ln. West Bloomfield, 48322 714 335-0248 http://www.fullercompliance.com

G2G Consulting 11000 Cedar Ave. Cleveland, OH, 44106 216 658-3995 http://g2gconsulting.com

GANTEC, Inc. 4520 E. Ashman Rd. Midland, 48642 989 631-9300 http://www.gantecinc.com

Garrison Dental Solutions 150 DeWitt Ln. Spring Lake, 49456 616 842-2244 http://www.garrisondental.com

GE Medical Systems Information 3300 Washtenaw Ave. Ann Arbor, 48104 N/A http://www.gehealthcare.com/usen/hit/index.html Technology

Gema Diagnostics 463 Rosewood Ave. East Lansing, 48823 517 775-3007 http://www.gemadiagnostics.com

Gene Codes 775 Technology Dr. Ann Arbor, 48108 734 769-7249 http://www.genecodes.com

Gene Codes Forensics, Inc. 775 Technology Dr., Ste. 100A Ann Arbor, 48108 734 769-7249 http://www.genecodesforensics.com

Geneflux Biosciences #509 55 E. Long Lake Rd. Troy, 48085 248 269-3755 http://www.geneflux.co.in

GeneGo, Inc. 500 Renaissance Dr. St. Joseph, 49085 269 983-7629 http://www.genego.com

Genemarkers LLC 4280 Commercial Ave. Portage, 49002 269 998-8116 http://www.genemarkersllc.com

Genentech 333 W. North Ave. Chicago, IL, 60610 650 225-1000 http://www.gene.com

Genomatix Software, Inc. 3025 Boardwalk Ann Arbor, 48108 877 436-6628 http://www.genomatix-software.com

Gerber Product Company 445 State St. Fremont, 49413 231 928-2000 http://www.gerber.com

Gerontology Network 500 Cherry St. SE Grand Rapids, 49503 616 456-6135 http://www.michiganseniors.org

Gifford, Krass, Sprinkle, P.O. Box 7021 Troy, 48007 248 647-6000 http://www.patlaw.com Anderson & Citkowski, P.C.

Gift of Life Michigan 3861 Research Park Dr. Ann Arbor, 48108 800 482-4881 http://www.giftoflifemichigan.org

Giri Diagnostics LLC 2611 Parmenter Blvd. Royal Oak, 48073 248 435-4472 http://www.giridiagnostics.com

GlaxoSmithKline 7890 Charline Court Lewis Center, OH, 43035 740 549-2426 http://www.gsk.com

Global Clinical Connections MTEC at the Groves at KVCC Kalamazoo, 49009 269 488-3277 http://www.globalclinicalconnections.com

Global Orphan Pharmaceutical, LLC 2155 Butterfield Dr. Troy, 48084 248 816-6881 http://www.gopharmaceutical.com

Global Remediation Technologies Inc. 1102 Cass St. Traverse City, 49684 800 899-3703 http://www.grtusa.com

Global Strategic Connections, LLC 2125 Butterfield Dr. Troy, 48084 248 816-6881 http://www.gsc-llc.com

GlyTag LLC 32375 Lahser Rd. Beverly Hills, 48025 313 577-9827 http://www.glytag.com

GotebörgBio - BRG 3260 Homestead Court Saline, 48176 734 429-4961 http://www.goteborgbio.se

Graminex, LLC 95 Midland Rd. Saginaw, 48638 877 472-6469 http://www.graminex.com

Grand River Aseptic Manufacturing P.O. Box 3696 Grand Rapids, 49501 616 331-6980 http://www.GrandRiverAPP.com

Grand Valley State University 301 Michigan St. NE Grand Rapids, 49503 616 331-8643 http://www.gvsu.edu

Grand Valley State University - Center for Entrepreneurship Grand Rapids, 49504 616 331-7257 http://www.gvsu.edu/cei Center for Entrepreneurship & Innovation

Great Lakes Drug Development, Inc. 123 Brighton Lake Rd. Brighton, 48116 810 224-7500 http://www.gldrugdev.com

Great Lakes Entrepreneur’s Quest 3520 Green Ct., Ste. 450 Ann Arbor, 48105 734 647-8951 http://www.gleq.org

Greater Mid-Michigan 1614 East Kalamazoo Lansing, 48912 517 999-3382 N/A Bio-Manufacturing Alliance (GMBMA)

H2 EnviroFuel P.O. Box 36129 Grosse Pointe Shores, 48236 910 232-7601 N/A

HAC of America, Inc. 1111 W.Centre Ave. Portage, 49024 800 445-9968 http://www.hacofamerica.com

Hamztec LLC 1039 Olivia Ave. Ann Arbor, 48104 734 476-8502 N/A

Hanger Prosthetics & Orthodics 2314 Gull Rd. Kalamazoo, 49001 269 345-1117 http://www.hanger.com/Pages/default.aspx




50



Hart Enterprises 400 Applejack Ct. Sparta, 49345 616 887-0400 http://www.hartneedles.com

Harvard Drug Company 31778 Enterprise Dr. Livonia, 48150 800 875-0123 http://www.harvarddrugs.com

Haviland Enterprises 421 Ann NW Grand Rapids, 49504 800 456-1134 http://www.havilandusa.com

Haworth, Inc. One Haworth Ctr. Holland, 49423 616 393-3000 http://www.haworth.com

Healthcare Management 31580 N. River Rd. Harrison Township, 48045 586 203-8257 http://www.nutrientpharmacology.com Associates, Inc.

HealthCure, LLC 390 Park St., Ste. 110 Birmingham, 48009 248 282-9300 http://www.healthcure.biz

Healthmark Industries Company Inc 33671 Doreka Dr. Fraser, 48026 800 521-6224 http://www.hmark.com

HealthMedia, Inc. 130 S. First St. Ann Arbor, 48104 734 623-0000 http://www.healthmedia.com

Healthtreat, Inc 30777 Northwestern Hwy., Ste. 300 Farmington Hills, 48334 248 855-0033 http://www.healthtreat.com

Hearing Health Science 1327 Jones Dr., Ste. 201 Ann Arbor, 48105 734 476-9490 http://www.hearinghealthscience.com

Helix Biological Laboratory 28044 James Dr. Warren, 48092 586 806-4243 http://www.helixbiolab.com

Helvetia Development Company LLC 225 Parsons St. Kalamazoo, 49007 877 626-5704 http://www.conformamed.com

Henry Ford Community College 5101 Evergreen Rd. Dearborn, 48128 800 585-HFCC http://www.hfcc.edu

Henry Ford Health Sciences Center 2799 W. Grand Blvd., ER-7099 Detroit, 48202 800 653-6568 http://www.henryfordhealth.org

Henry Ford Health System 2799 W. Grand Blvd. Detroit, 48202 313 916-2024 http://www.Henryford.com

Henry Ford Hospital 2799 W. Grand Blvd. Detroit, 48202 800 436-7936 http://www.henryfordhealth.org

Herman Miller Inc 855 E. Main Ave. Zeeland, 49464 616 654-3000 http://www.hermanmiller.com

HistoSonics, LLC 3626 W. Liberty Rd. Ann Arbor, 48103 734 926-4630 http://www.histosonics.com

HoMedics 3000 N. Pontiac Tr. Commerce Twp., 48390 248 863-3000 http://www.homedics.com

Honeywell Burdick & Jackson 1953 S. Harvey St. Muskegon, 49442 231 726-3171 http://www.bandj.com

Honigman Miller Schwartz and 350 E. Michigan Ave., Ste. 300 Kalamazoo, 49007 269 337-7700 http://www.honigman.com Cohn LLP

Hoover Precision Products, LLC 1390 Industrial Park Dr. Sault Ste. Marie, 49783 906 632-7310 http://www.hooverprecisionplastics.com

Horseshoe Herbals 1219 Anderson Rd. Niles, 49120 269 684-6888 http://www.horseshoeherbals.com

Housey Pharmaceutical Research 16800 W. 12 Mile Rd., Ste. 201 Southfield, 48076 248 663-7000 http://www.housey.com Laboratories, LLC

Hygieia, Inc. 330 E. Liberty St., Lower Lvl. Ann Arbor, 48104 734 527-9160 http://www.hygieiamedical.com

Hylant Group 24 Frank Lloyd Wright Dr., Ste. J4100 Ann Arbor, 48105 734 741-0044 http://www.hylant.com

i3 STATPROBE, Inc. 300 W. Morgan Rd. Ann Arbor, 48108 866 427-6848 http://www.i3statprobe.com

ImBio, LLC P.O. Box 131256 Ann Arbor, 48113 734 223-2142 http://imbio.com

In the Groove, LLC 7600 Madeline St. Saginaw, 48609 517 781-6030 http://www.inthegroovebrace.com

Incept BioSystems 401 W. Morgan Rd. Ann Arbor, 48108 734 302-3598 http://www.inceptbio.com

InformMed 1710 Hermitage Rd. Ann Arbor, 48104 734 332-0612 http://www.informmed.com

Inland Waters Pollution Control 2021 S. Schaefer Hwy. Detroit, 48217 800 992-9118 http://www.soave.com/core/diversified_inland.php

InnerSpace Corporation P.O. Box 2186 Grand Rapids, 49501 616 224-2828 http://www.stanleyinnerspace.com

InnoMotus LLC 3710 Frains Lake Ann Arbor, 48105 N/A N/A

Innova Therapeutics 800 Technology Dr. Ann Arbor, 48108 734 222-9900 N/A

Innovational Therapeutics 1404 Cambridge Rd. Ann Arbor, 48104 734 914-0550 N/A

Innovative Analytics 161 E. Michigan Ave., Haymarket 5th Kalamazoo, 49007 269 488-3200 http://www.ianalytics.biz

Innovative BioTherapies, Inc. 401 W. Morgan Rd. Ann Arbor, 48108 734 213-8350 http://www.innbio.com

Innovative Research Inc. 46430 Peary Ct. Novi, 48377 248 896-0145 http://www.innov-research.com

Innovative Surgical Solutions, LLC 21520 Bridge St. Southfield, 48033 248 416-0740 http://www.innovativesurgery.com

INRAD, Inc. 4375 Donker Ct. SE Kentwood, 49512 616 301-7800 http://www.inrad-inc.com

Insight Institute of Neurosurgery 4800 S. Saginaw St. Flint, 48507 810 732-8336 http://www.iinn.com and Neuroscience

Institute for Health Studies Michigan State Univ., D 132 W. Fee Hall East Lansing, 48824 517 349-1137 http://www.instituteforhealthstudies.com

Institute for Preventive Sports P.O. Box 7032 Ann Arbor, 48107 734 434-3390 http://www.ipsm.org Medicine






51

Integrated Compliance Solutions, LLC 4628 Landing Way Kalamazoo, 49048 269 383-5994 N/A

Integrated Nonclinical Development 3005 Miller Ave. Ann Arbor, 48103 734 929-5392 http://www.INDS-Inc.com Solutions, Inc. (INDS)

Integrated Sensing Systems (ISSYS) 391 Airport Industrial Dr. Ypsilanti, 48198 734 547-9896 http://www.mems-issys.com

Intermediary Biochemicals, LLC 2529 Dustin Rd. Okemos, 48864 517 336-4612 N/A

International Diagnostics 2620 S. Cleveland Ave., Ste. 100 St. Joseph, 49085 269 428-8400 http://www.ids-kits.com Systems Corp.

International Discovery Sourcing 300 N. Main St., Ste. 202 Chelsea, 48118 734 433-9670 http://www.idscbiotechnetwork.com Consultants LLC

International Food Protection 49 W. Michigan Ave., Ste. 300 Battle Creek, 49017 269 441-2995 http://www.ifpti.org Training Institute

International Partnership for Critical 828 W. Grand River Ave. Brighton, 48116 810 229-4158 http://www.cmod.org Markers of Disease (CMOD)

Intertek 4700 Broadmoor, Ste. 200 Kentwood, 49512 616 656-0601 http://www.intertek.com

Intervention Insights 710 Kenmoor, Ste. 120 Grand Rapids, 49546 616 949-7500 http://www.interventioninsights.com

INVIA Medical Imaging Solutions 3025 Boardwalk St., Ste. 200 Ann Arbor, 48108 734 205-1231 http://www.inviasolutions.com

IPGDx LLC P.O. Box 253 Harrisville, 48740 989 724-5631 http://www.ipgdx.com

J. Rettenmaier, USA 16369 US Hwy. 131 Schoolcraft, 49087 877 895-4099 http://www.jrsusa.com

Jasper Clinical Research & 526 Jasper St. Kalamazoo, 49007 269 276-8869 http://www.jasperclinic.com Development, Inc.

JHP Pharmaceuticals 870 Parkdale Rd. Rochester, 48307 248 656-5223 http://www.jhppharma.com

Jiva Pharma, Inc. 2929 Plymouth Rd., Ste. 207 Ann Arbor, 48105 734 262-0673 http://www.jivapharma.com

Johnson & Johnson One Johnson & Johnson Plaza New Brunswick, NJ, 08933 732 524-0400 http://www.jnj.com

Juvenile Diabetes Research 24359 Northwestern Hwy., #225 Southfield, 48075 248 355-1133 http://www.jdrfdetroit.org Foundation

JV Biolabs 2245 S. State St. Ann Arbor, 48104 734 395-7436 http://www.jvbiolabs.com

Kalamazoo College 1200 Academy St. Kalamazoo, 49006 269 337-7000 http://www.kzoo.edu

Kalamazoo College - Center for 1200 Academy St. Kalamazoo, 49006 269 337-5720 http://www.kzoo.edu/physics/ccss Complex System Studies

Kalamazoo Valley Community College 7107 Elm Valley Dr. Kalamazoo, 49009 269 353-1582 http://www.kvcc.edu

Kalexsyn, Inc. 4502 Campus Dr. Kalamazoo, 49008 269 488-8488 http://www.kalexsyn.com

Kalsec Inc. 3713 W. Main St. Kalamazoo, 49006 269 349-9711 http://www.kalsec.com

Kapnick Insurance Group 950 Victors Way, Ste. 10 Ann Arbor, 48108 888 263-4656 http://www.kapnick.com

KAR Bioanalytical, Inc. 4425 Manchester Rd. Kalamazoo, 49001 269 381-9666 http://www.karbio.com

Kellogg Company One Kellogg Sq. Battle Creek, 49016 800 962-1413 http://www.kelloggcompany.com

Kelly Services 999 W. Big Beaver Rd. Troy, 48084 248 244-4437 http://www.kellyservices.com

Kendle International 315 E. Eisenhower Pkwy., Ste. 214 Ann Arbor, 48108 734 274-8500 http://www.kendle.com

Kestrel Consultants, Inc. 410 Rose Dr. Ann Arbor, 48103 734 576-3031 http://www.KestrelConsultants.com

Kettering University 1700 W. Third Ave. Flint, 48504 810 762-9811 http://www.kettering.edu

Kettering University - Cooperative 1700 University Ave. Flint, 48504 810 762-9500 http://kettering.edu Education and Career Services Dept.

Keystone Solutions Group 5121 E. ML Ave., Ste. B-10 Kalamazoo, 49048 269 343-4108 http://www.keystone-pd.com

KnowledgeWatch 1327 Jones Dr. Ann Arbor, 48105 248 427-0726 http://www.knowledgewatch.com

Koch’s Orthotics and Prosthetics 5315 Elliot Dr., Ste. 104 Ypsilanti, 48197 734 434-0442 N/A

Komgen 3005 Whisperwood Dr., #288 Ann Arbor, 48105 734 272-5885 N/A

Koppert Biological Systems, Inc. 28465 Beverly Rd. Romulus, 48174 734 641-3763 http://www.koppertonline.com

KTM Industries 3327 Ranger Rd. Lansing, 48906 877 938-6738 http://www.ktmindustries.com

Labtech Industries 7707 Lyndon Detroit, 48238 313 862-1737 N/A

Lake Erie Wholesale Medical Supply 7560 Lewis Ave. Temperance, 48182 734 847-3847 N/A






52

Lake Superior State University 650 Easterday Ave. Sault Ste. Marie, 49783 906 632-6841 http://www.lssu.edu/eng/pdc

Lake Superior State University - 650 Easterday Ave. Sault Ste. Marie, 49783 906 635-2738 http://www.lssu.edu/eng/pdc Product Development Center

LaMed, Inc 54283 Meadowood Ct., Ste. 610 Shelby Township, 48316 248 650-0476 http://www.lamedinc.com

Lansing Community College P.O. Box 40010 Lansing, 48901 517 483-1957 http://www.lcc.edu

Lansing Community College - Box 40010 - MC:5400 Lansing, 48901 517 483-1092 http://www.mi-asm.org/MBP Molecular Biotechnology AAS Degree Program

Laser Mechanisms, Inc. / 25275 Regency Dr. Novi, 48375 248 474-9817 http://www.Oxid.com Oxid Corporation

Law Offices of Gary Kendra, PC 143 Cady Centre, #319 Northville, 48167 248 596-1879 http://www.kendralaw.com

Lawrence Technological University 2100 W. Ten Mile Rd. Southfield, 48075 248 204-3160 http://www.ltu.edu

LDI Incorporated 4311 Patterson SE Grand Rapids, 49512 N/A http://www.ldiinc.com

Lead Biopharma Consulting, LLC 7726 Brass Creek Ct. Dexter, 48130 734 418-2296 http://www.leadbiopharma.com

Leap Incorporated 500 E. Michigan Ave., Ste. 202 Lansing, 48912 517 702-3387 http://www.leapincorporated.com

LexaMed, Ltd. 705 Front St. Toledo, OH, 43650 419 693-5307 http://www.lexamed.net

Life Magnetics 1600 Huron Pkwy., Bldg. 520, 2nd Fl. Ann Arbor, 48109 734 277-2378 http://www.lifemagnetics.com

Linde Gas 2100 Western Ct., Ste. 100 Lisle, IL, 60532 734 424-1327 http://www.lindeus.com

Lodox PTY LTD 23360 Clarkshire South Lyon, 48178 248 446-8480 http://www.lodox.com

LVAD Technology, Inc. 300 River Pl., Ste. 6850 Detroit, 48207 313 446-2800 http://www.lvadtech.com

Lycera Corporation 46701 N. Commerce Center Dr., Ste. C Plymouth, 48170 734 233-3060 http://www.lycera.com

Lyman & Sheets Insurance Agency 2213 E. Grand River Ave. Lansing, 48901 517 482-2211 http://www.lymansheets.com

Lynn Medical Instruments P.O. Box 930459 Wixom, 48393 248 560-4500 http://www.lynnmed.com

Mager Scientific Inc. 1100 Baker Rd. Dexter, 48130 734 426-3885 http://www.magersci.com

Major Pharmaceuticals 31778 Enterprise Dr. Livonia, 48150 734 427-2576 http://www.majorpharmaceuticals.com

MarketLab Inc 6850 Southbelt Dr. Caledonia, 49316 616 656-2484 http://www.marketlabinc.com

Marketwire 200 W. Adams St., Ste. 2725 Chicago, IL, 60606 312 261-4212 http://www.marketwire.com

Maximax Pharmaceutical Research 35560 Grand River, Ste. 292 Farmington Hills, 48335 248 434-0180 http://www.maximax.com

Mayaterials, Inc. 661 Airport Blvd., Ste. 1 Ann Arbor, 48108 734 994-7035 http://www.mayaterials.com

MBI International 3815 Technology Blvd. Lansing, 48910 517 337-3181 http://www.mbi.org

McClinchey Histology Lab, Inc. 100 Rice St. Stockbridge, 49285 517 851-9149 http://www.mhistolab.com

McKesson Pharmacy Systems 30881 Schoolcraft Rd. Livonia, 48150 734 779-8800 http://www.mckesson.com

Mead Johnson Nutrition 725 E. Main St. Zeeland, 49464 812 429-5000 http://www.meadjohnson.com

MedArray, Inc. 3915 Research Park Dr., Ste. A-4 Ann Arbor, 48108 734 769-1066 http://www.permselect.com

Medbio, Inc. 630 S. Division Ave. Grand Rapids, 49503 616 245-0214 http://www.medbioinc.com

MedElephant, Inc. 21700 Northwestern Hwy., Ste. 110 Southfield, 48075 248 440-6640 http://www.medelephant.com

MedElute, Inc. 259 E. Michigan Ave., Ste. 407 Kalamazoo, 49007 269 352-3760 N/A

Medical Accessories & Research 219 N. Church St. Zeeland, 49464 888 527-6272 http://www.medacc.com Corporation

Medical Imaging Resources, Inc. 120 Enterprise Dr. Ann Arbor, 48103 888 323-1316 http://www.mobilemedicalimaging.com

Medical Main Street - Oakland 1200 Pontiac Lake Rd., Bldg. 41W Waterford, 48328 248 858-9099 http://www.medicalmainstreet.org County Planning & Economic Development

MedImage, Inc. 6276 Jackson Rd., Ste. G Ann Arbor, 48103 734 665-5400 http://www.medimage.com

Medi-Nuclear Corp. 30029 Research Dr. New Hudson, 48165 800 423-4226 http://www.medinuc.com/index.html

MediQuest Life Sciences, LLC 42030 Koppernick Rd., Ste. 309 Canton, 48187 734 455-7110 http://mediquestlifesciences.com

Meditrina Pharmaceuticals, Inc. 300 N. Fifth Ave., Ste. 150 Ann Arbor, 48104 734 926-0966 http://www.meditrina.com






53


Medtronic 620 Watson St. SW Grand Rapids, 49504 616 242-5200 http://www.medtronic.com

MemsTech 42503 Steepleview Northville, 48167 734 560-5506 http://www.memstech.com

Merck & Co. Inc. One Merck Dr. Whitehouse Station, NJ, 08889 908 423-1000 http://merck.com

Merit Laboratories, Inc. 2680 E. Lansing Dr. East Lansing, 48823 517 332-0167 http://www.meritlabs.com

Merit Network 1000 Oakbrook Dr., Ste. 200 Ann Arbor, 48104 734 615-6112 http://www.merit.edu

Metabolic Solutions Development 161 E. Michigan Ave., 4th Fl. Kalamazoo, 49007 269 343-6732 http://www.msdrx.com Company

MetagenX, LLC 4316 Aztec Way Okemos, 48864 517 203-0194 N/A

MI4Spine, LLC 1070 Timberlake Dr. Bloomfield Hills, 48302 248 535-6953 http://mi4spine.e-shopmall.com

Michigan Accelerator Fund I, LLC c/o The Charter Group, Grand Rapids, 49503 616 235-3555 N/A 99 Monroe Ave., NW, Ste. 506

Michigan Agri-Business Association 1501 North Shore Dr., Ste. A East Lansing, 48823 517 332-8663 http://www.miagbiz.org

Michigan Animal Model Consortium - Van Andel Research Institute, Grand Rapids, 49503 616 234-5684 http://www.ctaalliance.org Center for Technology Excellence 333 Bostwick Ave.

Michigan Antibody Technology 333 Bostwick Ave. Grand Rapids, 49503 616 234-5342 N/A Center - Center of Technology Excellence

Michigan Association of Health Plans 327 Seymour Ave. Lansing, 48933 517 371-3181 http://www.mahp.org

Michigan Biological Imaging Center - Western Michigan University, Dept. of Kalamazoo, 49008 269 387-5640 Center for Technology Excellence Biological Sciences, 3425 Woodhall http://www.wmich.edu/bios/facilities/imaging-center/index.html

Michigan Biomass Energy Program 611 W. Ottawa Lansing, 48909 517 241-6223 http://www.michigan.gov/biomass

Michigan Center for Biological 3600 Green Ct., Ste. 700 Ann Arbor, 48105 734 615-5914 http://www.ctaalliance.org/MCBI Information - Center for Technology Excellence

Michigan Center for Genomic WSU-5197 Biological Science Building, Detroit, 48202 313 577-9605 http://www.ctaalliance.org Technologies 5047 Gullen Mall

Michigan Center for Oral Health 1011 North University, Rm. 3228 Ann Arbor, 48109 734 647-4622 http://www.dent.umich.edu/research/clinicalresearch

Michigan Center for Structural MSU - Dept of Biochemistry, East Lansing, 48824 517 355-0199 http://mcsb.bch.msu.edu Biology - Center for Technology 310A Biochemistry Excellence

Michigan Center for Translational CCGC 5430, 1500 E. Medical Center Dr. Ann Arbor, 48109 734 615-4062 http://mctp.path.med.umich.edu/mctp/main/index.jsp Pathology

Michigan Chemistry Council 326 W. Ottawa, Capitol Corners Lansing, 48933 517 372-8898 http://michiganchemistry.com

Michigan Citizens for Stem Cell 27177 Lahser Rd., Ste. 102 Southfield, 48034 248 948-5555 http://www.StemCellResearchforMichigan.com Research and Cures (MCSCRC)

Michigan Corn Growers Association/ 12800 Escanaba Dr., Ste. B Dewitt, 48820 517 323-6600 http://www.micorn.org Corn Marketing Program of MI

Michigan Critical Care 3550 W. Liberty, Ste. 3 Ann Arbor, 48103 734 995-9089 http://www.mc3corp.com Consultants (MC3)

Michigan Dental Association 325 W. Lake Lansing Rd., Ste. C East Lansing, 48823 517 332-8663 http://www.smilemichigan.com

Michigan Diagnostics LLC 2611 Parmenter Blvd. Royal Oak, 48073 248 435-4472 http://www.michdiag.com

Michigan Ear Institute 30055 Northwestern Hwy., Ste. 101 Farmington Hills, 48334 248 865-4030 http://www.stjohndoctors.org

Michigan Economic Development 300 N. Washington Sq. Lansing, 48913 517 373-9808 http://www.michiganadvantage.org Corporation

Michigan Health & Hospital Assoc. 6215 W. St. Joseph Hwy. Lansing, 48917 517 323-3443 http://www.mha.org

Michigan Health Council 2410 Woodlake Dr. Okemos, 48864 517 347-3332 http://www.mhc.org

Michigan High Throughput MTEC at Kalamazoo Valley Community Kalamazoo, 49009 269 353-1582 http://mhtsc.kvcc.edu Screening Center - Center of College, 7107 Elm Valley Drive Technology Excellence

Michigan Instruments 4717 Talon Ct. SE Grand Rapids, 49512 616 554-9696 http://www.michiganinstruments.com

Michigan Life Science and 46701 Commerce Center Dr. Plymouth, 48170 734 233-3050 http://www.mlsic.com Innovation Center (MLSIC)

Michigan Manufacturing 47911 Halyard Dr. Plymouth, 48170 888 414-6682 http://www.mmtc.org Technology Center

Michigan Medical Device Acclerator 241 E. Michigan Ave. Kalamazoo, 49007 N/A http://www.mmdaccelerator.com





54

MichBio MeMBer AnnuAl corporAte SponSor preferred providerMichBio MeMBer AnnuAl corporAte SponSor preferred provider

Michigan Medical Device Association 301 Catrell Dr. Howell, 48844 800 930-5698 http://www.mmda.org

Michigan Molecular Institute 1910 W. Saint Andrews Rd. Midland, 48640 989 832-5555 http://www.mmi.org

Michigan Nanotechnology Institute 1150 W. Medical Center Dr., Ann Arbor, 48109 734 647-2777 http://www.nano.med.umich.edu for Medicine & Biological Science SPC 5648, 9220C MSRB III

Michigan Nurses Association 2310 Jolly Oak Rd. Okemos, 48864 517 349-5818 http://www.minurses.org

Michigan Orthodontic Appliances 1013 E. 3rd St. Royal Oak, 48067 248 544-0860 N/A

Michigan Orthopedic Services 13450 Farmington Rd. Livonia, 48150 734 513-8205 http://www.michortho.com

Michigan Osteopathic Association 2445 Woodlake Cir. Okemos, 48864 517 347-1555 http://www.mi-osteopathic.org/index.php

Michigan Primary Care Association 7215 Westshire Dr. Lansing, 48917 517 381-8000 http://www.mpca.net

Michigan Proteome Consortium - 300 North Ingalls Bldg., 11th Fl., Rm. 1198 Ann Arbor, 48109 734 763-3130 http://www.proteomeconsortium.org Center for Technology Excellence

Michigan Public Health Institute 2440 Woodlake Cir., Ste. 190 Okemos, 48864 517 324-9397 http://www.mphi.org

Michigan Research Institute 401 W. Morgan Rd. Ann Arbor, 48108 734 302-3200 http://www.annarborusa.org/expand-relocate/regional-data/rd-labs-testing

Michigan Science Teachers Assoc. 3300 Washtenaw Ave., Ste. 220 Ann Arbor, 48104 734 973-0433 http://www.msta-mich.org

Michigan Small Business & Grand Valley State Univ./Seidman Grand Rapids, 49504 616 331-7480 http://www.misbtdc.org Technology Development Center College of Business, 510 W. Fulton St.

Michigan Soybean Promotion 140 W. Tuscola St. Frankenmuth, 48734 989 652-3294 http://www.michigansoybean.org Committee

Michigan State Medical Society 120 W. Saginaw Rd. East Lansing, 48826 517 337-1651 http://www.msms.org

Michigan State University 250 Hannah Administration Bldg. East Lansing, 48824 517 355-8332 http://www.msu.edu

Michigan State University - 3536 Engineering Bldg. East Lansing, 48824 517 353-5013 http://www.egr.msu.edu/DER/labs/bdrl.html BioMechanical Design Research Lab

Michigan State University - 322 North Kedzie Hall East Lansing, 48824 517 353-7800 http://bld.msu.edu Biomedical Laboratory Diagnostics Program

Michigan State University - 2172 Biomedical Physical Lansing, 48824 517 355-2150 N/A Center for Fundamental Sciences Bldg. Materials Research

Michigan State University - 102 Agriculture Hall East Lansing, 48824 517 355-0232 http://www.maes.msu.edu College of Agriculture & Natural Resources

Michigan State University - A110 East Fee Hall East Lansing, 48824 517 353-1730 http://humanmedicine.msu.edu College of Human Medicine

Michigan State University - 3410 Engineering Bldg. East Lansing, 48824 517 355-5113 http://www.egr.msu.edu College of Engineering

Michigan State University - A221 Life Sciences East Lansing, 48824 517 355-5765 http://nursing.msu.edu College of Nursing

Michigan State University - A-310 East Fee Hall East Lansing, 48824 517 355-1855 http://www.msu.edu College of Osteopathic Medicine

Michigan State University - G-100 Veterinary Medical Ctr. East Lansing, 48824 517 355-6509 http://cvm.msu.edu College of Veterinary Medicine

Michigan State University - B405 Life Sciences East Lansing, 48824 517 353-9619 http://phmtox.msu.edu/index.html Dept. of Pharmacology & Toxicology

Michigan State University - 2201 Biomedical Physical Sciences Bldg. East Lansing, 48824 517 355-6475 http://www.psl.msu.edu Dept. of Physiology

Michigan State University - 1000 Oakland Dr. Kalamazoo, 49008 616 337-6010 http://www.kcms.msu.edu Kalamazoo Center for Medical Studies

Michigan State University - 301 Administration Bldg. East Lansing, 48824 517 355-5040 http://www.cga.msu.edu MSU Technologies

Michigan State University - Office of 301 Administration Bldg. East Lansing, 48824 517 355-5040 http://www.cga.msu.edu Contract and Grant Administration





MichBio MeMBer AnnuAl corporAte SponSor preferred providerMichBio MeMBer AnnuAl corporAte SponSor preferred providerMichBio MeMBer AnnuAl corporAte SponSor preferred provider

55

Michigan State University - Office of 120 W. Saginaw Rd. East Lansing, 48826 517 337-1651 http://www.vprgs.msu.edu Research & Graduate Studies

Michigan State University - 80 Agriculture Hall East Lansing, 48824 517 432-1676 http://www.productcenter.msu.edu Product Center for Agriculture and Natural Resources

Michigan Surgical Equipment LLC 48797 West Rd. Wixom, 48393 248 349-5859 http://www.michigansurgical.com

Michigan Technological University 1400 Townsend Dr., Harold Meese Bldg. Houghton, 49931 888 688-1885 http://www.admin.mtu.edu/iptc

Michigan Technological University - 1400 Townsend Dr., Advanced Tech. Houghton, 49931 906 487-2228 http://www.mtu.edu Office of Technology and Development Complex Economic Development

Michigan Technology and Research 2245 S. State St., Ste. 1100 Ann Arbor, 48104 734 222-0009 http://www.MTRInstitute.com Institute, LLC

Michigan Universities University of Michigan, Wolverine Tower Ann Arbor, 48109 734 647-5730 http://www.muci.org Commercialization Initiative (MUCI) Rm. 1006, 3003 S. State St.

Michigan Venture Capital Association 425 N. Main St. Ann Arbor, 48104 734 223-3750 http://www.michiganvca.org

Micro Machine Company 2429 N. Burdick St. Kalamazoo, 49007 269 388-2440 http://www.micromachineco.com

Microcide, Inc. 2727 Second Ave. #334 Detroit, 48201 888 342-6279 http://www.microcide.com

MicroDose Life Sciences, LLC 38955 Hills Tech Dr. Farmington Hills, 48331 248 489-1190 N/A

Micromyx, LLC 4717 Campus Dr. Kalamazoo, 49008 269 372-3758 http://www.micromyx.com

Midbrook, Inc. 2080 Brooklyn Rd. Jackson, 49203 517 787-3481 http://www.midbrook.com

MidMichigan Innovation Center 4520 E. Ashman Rd., Ste. M Midland, 48642 989 839-2333 http://www.mmic.us

Midwest Cleanroom Associates, Inc. 2055 Oak Industrial Dr., Ste. A Grand Rapids, 49505 616 458-8533 http://www.mcacleanrooms.com

Milad Pharmaceutical Consulting Michigan Life Science & Innovation Ctr., Plymouth, 48170 734 664-0394 http://www.miladpharmaconsulting.com 46701 Commerce Center Dr., Ste. D

Miller Technical Services 7444 Haggerty Rd. Canton, 48187 734 738-1961 http://www.nextmobilitynow.com

Miller, Canfield, Paddock and 840 W. Long Lake Rd., Ste. 200 Troy, 48098 313 963-6420 http://www.millercanfield.com Stone, P.L.C.

MIR Preclinical Services 800 Technology Dr. Ann Arbor, 48108 734 821-1063 http://www.molecularimaging.com (Molecular Imaging Research)

MIT Enterprise Forum 3765 Sancroft Ave. West Bloomfield, 48324 N/A http://www.mitgreatlakes.org

MitoStem 440 Burroughs Detroit, 48202 313 879-5250 http://www.mitostem.com

MMS Holdings, Inc. 6880 Commerce Blvd. Canton, 48187 734 245-0310 http://www.mmsholdings.com

Molecular Innovations Inc. 46430 Peary Ct. Novi, 48377 888 557-5055 http://www.mol-innov.com

Monitor Liability Managers Inc. 2850 W. Golf Rd., Ste. 800 Rolling Meadows, IL, 60008 847 806-6590 http://www.monitorliability.com

Monteris Medical, Inc. 350 E. Michigan Ave., Ste. 215 Kalamazoo, 49007 269 372-0455 http://www.monteris.com/index.htm

MPI Research 54943 N. Main St. Mattawan, 49071 269 668-3336 http://www.mpiresearch.com

MS Bioworks 3950 Varsity Dr. Ann Arbor, 48108 734 929-5083 http://www.msbioworks.com

Mt. Clemens Orthopaedic 24432 Crocker Blvd. Clinton Township, 48036 586 463-3600 N/A Appliances, Inc

MuciMed, Inc 259 E. Michigan Ave., Ste. 409 Kalamazoo, 49007 906 842-3212 N/A

M-Vision Inc. 12420 Stanley Dr. Belleville, 48111 734 697-3933 http://www.m-visioninc.com

Mycol Balm Laboratories, Inc. 9595 Raucholz Rd. St. Charles, 48655 989 585-4357 http://www.mycolbalm.com

MYcroarray (Biodiscovery, LLC) 5692 Plymouth Rd. Ann Arbor, 48105 734 998-0751 http://www.mycroarray.com

NanoBio Corporation 2311 Green Rd., Ste. A Ann Arbor, 48105 734 302-4000 http://www.nanobio.com

Nanoderm Therapeutics, Inc. 3081 N. Foxridge Ct. Ann Arbor, 48105 734 665-4105 N/A

NanoSystems Inc. 3588 Plymouth Rd., Ste. 326 Ann Arbor, 48105 734 274-0020 N/A

NanoVir LLC 4717 Campus Dr., Ste. 1300 Kalamazoo, 49008 269 372-3261 http://www.nanovirpharm.com

National Center for Manufacturing 3025 Boardwalk Ann Arbor, 48108 800 222-6267 http://www.ncms.org Sciences

National Kidney Foundation of MI 1169 Oak Valley Dr. Ann Arbor, 48108 734 222-9800 http://www.nkfm.org

Natural Therapeutics, LLC 401 W. Morgan Rd. Ann Arbor, 48108 888 491-7770 http://www.fungalnailrelief.com

Neocutis, Inc. 512 E. 11 Mile Rd., Ste. 100 Royal Oak, 48067 248 544-3140 http://www.neocutis.com






56

Neogen Corporation 620 Lesher Pl. Lansing, 48912 800 234-5333 http://www.neogen.com

NephRx Corporation 4717 Campus Dr., Ste. 100 Kalamazoo, 49008 269 372-8703 http://www.nephrx.com

NeuMedicine 800 W. Grand River Ave. Brighton, 48116 877 563-8633 http://www.neumedicine.com

NeuroNexus Technologies, Inc. 655 Fairfield Ct., Ste. 100 Ann Arbor, 48108 734 913-8858 http://www.neuronexustech.com

Nexeton Biomedical, LLC 5624 Sherwood Rd. Oxford, 48371 248 941-9837 N/A

Next Generation Therapeutics, Inc. 46701 Commerce Center Dr., Ste. A-6 Plymouth, 48170 734 527-9139 http://www.nextgenerationtherapeutics.com

NEXT Mobility 7444 Haggerty Rd. Canton, 48187 888 489-6398 http://www.nextmobilitynow.com

NextGen Metabolomics, Inc. 7395 Warren Rd. Ann Arbor, 48105 734 265-0884 http://www.nextgenmetabolomics.com

NextGen Sciences, Inc. 4401 Varsity Dr., Ste. E Ann Arbor, 48108 734 973-7914 http://www.nextgensciences.com

Nitrate Elimination Company, Inc. 334 Hecla St. Lake Linden, 49945 888 648-7283 http://www.nitrate.com

North Bay Bioscience 13606 S. W. Bay Shore Dr. Traverse City, 49685 231 922-2211 http://www.nbbs.com

Northern Biomedical Research, Inc. 930 W. Sherman Blvd. Muskegon, 49441 231 759-2333 N/A

Northern Michigan University 309 Cohodas Marquette, 49855 906 227-1000 http://www.nmu.edu

Northwest Orthotics-Prosthetic, Inc. 39830 Grand River, Ste. B1d Novi, 48375 248 477-1443 N/A

Norwind-Cortez 305 N. Hewitt Ypsilanti, 48197 734 434-0575 N/A

Novalung, Inc. 3550 W. Liberty, Ste. 3 Ann Arbor, 48103 N/A http://www.novalung.com

NSF International 789 N. Dixboro Rd. Ann Arbor, 48105 734 769-8010 http://www.nsf.org

NuStep 5111 Venture Dr., Ste. 1 Ann Arbor, 48108 734 769-8180 http://www.nustep.com

Nutriinfo.com 41850 W. 11 Mile Rd., Ste. 106 Novi, 48375 866 533-7172 https://www.nutriinfo.com/index_ssl.html

Nymirum 3510 W. Liberty Rd. Ann Arbor, 48103 734 369-4268 http://www.nymirum.com

Oakland Community College 2480 Opdyke Rd. Bloomfield HIlls, 48304 248 341-2000 http://www.oaklandcc.edu

Oakland Community College 27055 Orchard Lake Rd., C-101 Farmington Hills, 48334 248 522-3741 http://www.oaklandcc.edu/MolecularBiotechnology (Orchard Lake Campus) - Biotechnology Program

Oakland Genetics LLC 2925 Bond Rochester Hills, 48309 248 257-0000 http://www.oaklandgenetics.com

Oakland University 520 Dowd Hall Rochester, 48309 248 370-2100 http://www.oakland.edu

Oakland University - Center for Oakland University, 205 SEB Rochester, 48309 248 370-2085 http://www2.oakland.edu/cbr Biomedical Research

Oakland University - Eye Research 2200 N. Squirrel Rd. Rochester, 48309 248 370-2395 http://www.oakland.edu/eri Institute

Oakland University - William 216 O’Dowd Hall, 2001 N. Squirrel Rd. Rochester, 48309 248 370-2767 http://www.oakland.edu/medicine Beaumont School of Medicine

OcuSciences, Inc. 3201 Asher Rd. Ann Arbor, 48104 734 646-4156 http://www.ocusciences.com

Office Depot 800 Eisenhower Pkwy. Ann Arbor, 48106 734 259-9281 http://www.officedepot.com

OLC-BIO, LLC 8615 Richardson Rd., Ste. 300 Commerce, 48390 248 242-5902 http://www.olc-bio.com

Omega Surgical Instruments, Inc. G-8395 S. Saginaw St. Grand Blanc, 48439 800 656-6342 http://www.omegasurgical.com

OncoImmune, Inc. 333 Parkland Plz., Ste. 1000 Ann Arbor, 48103 734 332-4234 http://www.oncoimmune.com

Oncologix Tech 206 Crown St. SW Grand Rapids, 49548 616 977-9933 N/A

Ophthigenics LLC 2900 Huron Pkwy., Ste. 4 Ann Arbor, 48105 734 972-7505 http://www.ophthigenics.com

Ophthy-DS, Inc. 54943 N. Main St. Mattawan, 49071 269 250-2177 http://www.Ophthy-DS.com

Optical Dimensions 3285 Martin Rd. #110 Walled Lake, 48390 800 878-5367 http://opticaldimensionslab.com/default.aspx

Optical Supply 1526 Plainfield Ave., NE Grand Rapids, 49505 616 361-6000 http://www.optical-supply.com

Orchid Bio-Coat Orthopedic Solutions 21249 Bridge St. Southfield, 48034 248 352-4570 http://www.orchid-orthopedics.com/biocoat

Orchid Bio-Vac Orthopedic Solutions 21316 Bridge St. Southfield, 48033 248 350-2150 http://www.orchid-orthopedics.com/biovac

Orchid Stealth 1489 Cedar St. Holt, 48842 517 694-2300 http://www.orchid-orthopedics.com






57

Orchid Unique Orthopedic Solutions 6688 Dixie Hwy. Bridgeport, 48722 989 746-0780 http://www.orchid-orthopedics.com/unique

Originus, Inc. 3985 Research Park Dr., Ste. 200 Ann Arbor, 48108 734 913-8791 http://www.originusinc.com

Orthopedic Development, Inc. 6565 W. Main St. Kalamazoo, 49009 269 544-4715 N/A

Ostial Solutions 1111 Short Rd. Kalamazoo, 49008 269 383-3797 http://www.ostialsolutions.net

OtoMedicine, Inc. 330 E. Liberty St., Lower Level Ann Arbor, 48104 269 615-0668 http://www.otomedicine.com

Oxford Biomedical Research, Inc. 2165 Avon Industrial Dr. Rochester Hills, 48309 248 852-4466 http://www.oxfordbiomed.com

Painex Corporation 18295 James Couzens Hwy. Detroit, 48235 313 863-1200 http://www.ringmasternow.com/index.html

Pall Corporation - Life Sciences 600 S. Wagner Rd. Ann Arbor, 48103 800 521-3160 http://www.pall.com

Paragon Laboratories, Inc. 12649 Richfield Ct. Livonia, 48150 734 462-3900 http://www.paragonlaboratories.com

Pathology Experts, LLC 2887 Oakhaven Ct. Midland, 48642 989 631-2790 http://www.pathexperts.com

PBS Biotech 2843 E. Grand River Ave., Ste. 262 East Lansing, 48823 888 PBS-0022 http://pbsbiotech.com

Performance Systematix Inc. 5569 33rd St., SE Grand Rapids, 49512 616 949-9090 http://www.psix.com

Performance Validation LLC 5148 Lovers Ln., Ste. 200 Portage, 49024 269 373-9112 http://www.perfval.com

Perrigo Company 515 Eastern Ave. Allegan, 49010 269 673-8451 http://www.perrigo.com

Pfizer Inc. 7000 Portage Rd. Kalamazoo, 49001 269 833-4000 http://www.pfizer.com

PG Pharmaceuticals, Inc. 2246 N. Monroe St. Monroe, 48162 248 632-1666 http://www.pg-pharma.com

Phadia US 4169 Commercial Ave. Portage, 49002 800 346-4364 http://www.phadia.us

Pharmaceutical Research and 950 F St., NW, Suite 300 Washington, DC, 20004 202 835-3400 http://www.phrma.org Manufacturers of America (PhRMA)

Pharmacision LLC 1947 Mistwood Ct. Canton, 48187 734 895-3670 http://www.pharmacision.com

PharmaMed Resources, LLC 3616 East T Ave. Portage, 49002 269 303-0798 http://www.pharmamedresources.com

PharmMor Consulting, LLC P.O. Box 2570 Portage, 49081 269 327-2215 N/A

PharmOptima, LLC 6710 Quality Way Portage, 49002 269 329-4370 http://www.pharmoptima.com

Phillips Plastics Corporation 5706 Stonington Ct. West Bloomfield, 48322 248 851-8300 http://www.phillipsplastics.com

Phrixus Pharmaceuticals, Inc. 300 N. Fifth Ave., Ste. 150 Ann Arbor, 48104 734 358-9015 http://www.phrixuspharmaceuticals.com

PhycoTech 620 Broad St., Ste. 100 St. Joseph, 49085 269 983-3654 http://www.phycotech.com

Physician’s Technology, LLC 23 E. Front St. Monroe, 48161 734 241-5060 http://www.willomd.com

PICOCAL 333 Parkland Plz. Ann Arbor, 48103 734 913-2608 http://www.picocal.com

Pioneer Surgical Technology 375 River Park Cir. Marquette, 49855 906 226-9909 http://www.pioneersurgical.com

Pixel Velocity Inc. 3917 Research Park Dr., Ste. 1B Ann Arbor, 48108 734 213-3715 http://www.pixel-velocity.com

Plas-Labs, Inc. 401 E. North St. Lansing, 48906 517 372-7177 http://www.plas-labs.com

Pointe Scientific, Inc. 5449 Research Dr. Canton, 48188 800 445-9853 http://www.pointescientific.com

POLY Bioinformatics P.O. Box 1327 Ann Arbor, 48106 734 678-7342 http://www.polyergic.com

Precision Edge Surgical Products 415 W. 12th Ave. Sault Ste. Marie, 49783 906 632-4800 http://www.precisionedge.com

Price, Heneveld, Cooper, DeWitt & 695 Kenmoor SE Grand Rapids, 49501 616 949-9610 http://www.priceheneveld.com Litton

Progressive Dynamics Medical 507 Industrial Rd. Marshall, 49068 269 781-4241 http://www.progressivedynamicsmedical.com

ProNAi Therapeutics, Inc. 4717 Campus Dr., Ste. 1100 Kalamazoo, 49008 269 815-8098 http://www.pronai.com

ProPharma Group 8175 Creekside Dr. Portage, 49024 269 321-5170 http://www.propharmagroup.com

ProReg Resources, LLC 8889 2nd St. Mattawan, 49071 269 372-2911 http://www.proregresources.com

Pros-Tech 1717 Stephenson Hwy. Troy, 48083 248 680-2800 http://www.pros-tech.com

Prosthetic Center, Inc. 1200 S. Washington Ave. Lansing, 48910 517 372-7007 N/A

Proteos, Inc. 4717 Campus Dr. Kalamazoo, 49008 269 372-3423 http://www.proteos.net

Proud Mary Prosthetics 6305 Wall St. Sterling Heights, 48312 877 627-9272 http://www.proudmaryprosthetics.com

PVS Chemicals, Inc. 10900 Harper Ave. Detroit, 48213 313 921-1200 http://www.pvschemicals.com

Qtox, LLC 1828 Yosemite Dr. Okemos, 48864 517 944-2022 N/A

Quality Air Service, Inc. 6701 Quality Way Portage, 49002 269 327-3055 http://www.qairservice.com






58

Quality Care Products 7560 Lewis Ave. Temperance, 48182 734 847-3847 http://www.qcpmeds.com

Quantum Laboratories 28221 Beck Rd., Ste. A-11 Wixom, 48393 248 348-8378 http://www.quantumlaboratories.com

QuatRx Pharmaceuticals 777 E. Eisenhower Pkwy., Ste. 100 Ann Arbor, 48108 734 913-9900 http://www.quatrx.com

Quest Diagnostics Incorporated 4444 Giddings Rd. Auburn Hills, 48326 248 373-9120 http://www.questdiagnostics.com

Quest Research Institute 31000 Telegraph, Ste. 230 Bingham Farms, 48025 248 644-7770 http://www.questri.com

Rader, Fishman & Grauer PLLC 39533 Woodward Ave., Suite 140 Bloomfield Hills, 48304 248 594-0600 http://www.raderfishman.com

Ranir, LLC 4701 E. Paris Ave. SE Grand Rapids, 49512 616 698-8880 http://www.ranir.com

Rapid BioSense 3900 Collins Rd. Lansing, 48910 800 579-4913 http://www.rapidbiosense.com

RealBio Technology, Inc. 4717 Campus Dr., Ste. 1500 Kalamazoo, 49008 269 544-1088 http://www.realbiotechnology.com

Regional Medical Lab, Inc. 175 College St. Battle Creek, 49037 269 969-6161 http://www.rml-lab.com

ReNew Systems P.O. Box 1072 Bay City, 48706 989 892-4552 http://www.renewsystems.com

Renko Enterprises, LLC 25344 Carollton Dr. Farmington Hills, 48335 248 342-6472 N/A

Research Essential Services 46701 Commerce Center Dr. Plymouth, 48170 734 645-1276 http://www.ressential.com

RetroSense Therapeutics, LLC P.O. Box 625 Northville, 48167 248 924-3298 http://www.retro-sense.com

RG Medical Diagnostics 28351 Beck Rd., Ste. G5 Wixom, 48393 888 596-9498 http://www.rgmd.com

Richard-Allan Scientific 4481 Campus Dr. Kalamazoo, 49008 616 644-2400 http://www.rallansci.com

Rigaku Innovative Technologies 1900 Taylor Rd. Auburn Hills, 48326 248 232-6400 http://www.rigaku.com

RightAnswer.com, Inc. 4520 E. Ashman Rd., Ste. R Midland, 48642 989 835-5000 http://www.rightanswer.com

RJL Systems, Inc. 33939 Harper Ave. Clinton Township, 48035 586 790-0200 http://www.rjlsystems.com

Robertson Research Institute 4215 Fashion Square Blvd. Saginaw, 48603 989 799-8720 http://www.robertsoninstitute.org

Roche Labs 38777 Six-Mile Rd. Livonia, 48152 734 525-0248 N/A

Rockwell Medical Technologies, Inc. 30142 Wixom Rd. Wixom, 48393 248 960-9009 http://www.rockwellmed.com

Rose Technologies 1440 Front Ave. NW Grand Rapids, 49504 616 233-3000 http://www.rose-technologies.com

Roush Life Sciences 12447 Levan Livonia, 48150 734 779-7006 http://www.roush.com

RTI Health Solutions 3005 Boardwalk St., Ste. 105 Ann Arbor, 48108 734 213-5372 http://www.rtihs.org

RTI Laboratories, Inc. 33080 Industrial Rd. Livonia, 48150 734 422-8000 http://www.rtilab.com

Rubicon Genomics, Inc. 4355 Varsity Dr., Ste. E Ann Arbor, 48108 734 677-4845 http://www.rubicongenomics.com

RxDispense, Inc. 2706 Cumberland Berkley, 48072 734 277-0668 http://www.rxdispense.com

S & J Laboratories 4669 Executive Dr. Portage, 49002 269 324-7383 http://www.sandjlab.com/index.html

Saginaw Valley State University 7400 Bay Rd. University Center, 48710 989 964-4080 http://www.svsu.edu

Sakor Technologies, Inc. 2855 W. Jolly Rd. Okemos, 48864 517 332-7256 http://www.sakor.com

SanoBio Therapeutics LLC 808 E. Kingsley Ann Arbor, 48104 N/A http://sanobio.com

sanofi-aventis US 55 Corporate Dr. Bridgewater, NJ, 08807 636 273-5409 http://en.sanofi-aventis.com

ScarPrev Pharmaceuticals 917 Packard St. Ann Arbor, 48104 734 717-9263 N/A

Science Direct 3675 Crestwood Pkwy., Ste. 400 Duluth, GA, 30096 770 935-6077 http://www.elsevier.com

SciMedLit, LLC 2435 Merrill Ypsilanti, 48197 734 972-5333 http://www.scimedlit.com

SciTech Development 440 Burroughs, Ste. 520 Detroit, 48236 313 966-7317 http://www.scitechdevelopment.com

ScreenTrack 1603 Peach St. Ann Arbor, 48105 734 665-0701 N/A

Secretory IgA Inc. 803 N. Main St. Ann Arbor, 48104 734 994-0966 http://www.secretoryiga.com

Secure Mount 415 Condad St. Jackson, 49202 517 784-9613 http://www.securemount.com

Selective Technologies, Inc. 132 W. First St. Flint, 48502 810 767-7530 N/A

SenSound, LLC 440 Burroughs St., Ste. 170 Detroit, 48202 313 882-1065 http://www.sensound.com

Sentry Medical Technologies 1039 Olivia Ave. Ann Arbor, 48104 734 476-8502 N/A

Sequenom Center for Molecular 301 Michigan St. NE, Ste. 580 Grand Rapids, 49503 616 391-4330 http://www.cmmdx.org Medicine

Shrader Analytical and Consulting 440 Burroughs, Ste. 340 Detroit, 48202 313 894-4440 http://www.shraderlabs.com Laboratories, Inc.






59

Siemens Ultrasound Division 400 W. Morgan Rd. Ann Arbor, 48108 734 995-5010 http://www.usa.siemens.com

Signal Medical Corporation 400 Pyramid Marysville, 48040 810 364-7070 http://www.signalmd.com

Sikich Investment Banking 225 W. Washington, Ste. 1610 Chicago, IL, 60606 312 458-0000 http://www.sikich.com

Single Source Procurement, LLC 4717 Campus Dr. Kalamazoo, 49008 269 372-3997 http://www.sspusa.com

SkinTreet, LLC 1120 Olivia Ave. Ann Arbor, 48104 734 663-5999 N/A

Skyline Property Group, Inc. 2146 Livernois Troy, 48083 248 680-9900 http://www.commercialrealestatemichigan.net

Skytron 5085 Corporate Exchange Blvd. Grand Rapids, 49512 800 759-8766 http://www.skytron.us

Slaughter Instrument Co. 4356 N. Roosevelt Stevensville, 49127 269 428-7471 http://www.slaughtercoinc.com

Soar Technology, Inc. 3600 Green Ct., Ste. 600 Ann Arbor, 48105 734 327-8000 http://www.soartech.com

SoloHill Engineering, Inc. 4370 Varsity Dr., Ste. B Ann Arbor, 48108 734 973-2956 http://www.solohill.com

Somanetics Corporation 2600 Troy Center Dr. Troy, 48084 248 244-1400 http://www.somanetics.com

Sonetics Ultrasound, Inc. 3550 W. Liberty, Ste. 3 Ann Arbor, 48103 734 260-4800 N/A

Southwest Michigan First 241 E. Michigan Ave. Kalamazoo, 49024 269 553-9588 http://www.southwestmichiganfirst.com

Southwest Michigan Innovation 4717 Campus Dr., Ste. 100 Kalamazoo, 49008 269 353-1823 http://www.kazoosmic.com Center

Spartan Medical Supply 50762 Kiawah Tr. Mattawan, 49071 866 894-5118 http://www.spartanmedicalsupply.com

SPI Pharma P.O. Box 226 Grand Haven, 49417 231 935-6900 http://www.spipharma.com

Spinal Ventures, LLC 5126 Girard Dr. Pinckney, 48169 810 231-6600 N/A

SSV Therapeutics, LLC 2929 Plymouth Rd. Ann Arbor, 48105 734 262-0673 http://ssvtherapeutics.com

Staubli Corporation 44467 Charnwood Dr. Plymouth, 48170 734 417-4970 http://www.staubli.com

Stem Cell Growth Inc. 29580 Northwestern Hwy., Ste. 110 Southfield, 48034 248 343-4842 http://www.stemcellgrowthinc.com

Sterling Diagnostics 36645 Metro Ct. Sterling Heights, 48312 586 979-2141 http://www.sterlingdiagnostics.com

Stryker Corporation 2825 Airview Blvd. Kalamazoo, 49002 269 385-2600 http://www.stryker.com

Stryker Instruments 4100 E. Milham Ave. Kalamazoo, 49001 269 323-7700 http://www.stryker.com/instruments

Stryker Interventional Pain 2825 Airview Blvd. Kalamazoo, 49002 269 385-2600 N/A

Stryker Orthopaedics 44736 Helm St. Plymouth, 48170 734 454-0023 http://www.stryker.com/en-us/corporate/ContactUs/Orthopaedics/index.htm

Stryker Osteosynthesis 2825 Airview Blvd. Kalamazoo, 49002 N/A http://www.osteosynthesis.stryker.com

SubTerra LLC 104 Wilcox Rd. White Pine, 49971 906 885-5953 http://www.subterrallc.com

Sunapten Therapeutics, Inc. 4717 Campus Dr., Ste. 1000 Kalamazoo, 49008 N/A http://www.sunapten.com

Superior Growers Supply 4870 Dawn Ave. East Lansing, 48823 800 227-0027 http://www.superiorgrowers.com

Surefil LLC 4560 Danvers Dr. SE Grand Rapids, 49512 616 532-1700 http://www.surefil.com

Surface Enhancement Solutions 320 Hillboro Dr. Bloomfield Hills, 48301 248 930-0851 http://surfaceenhancementsolutions.com

Surge Medical Solutions 8850 M-89 Richland, 49083 888 307-1144 http://www.surgemedical.com

SurgiTel 77 Enterprise Dr. Ann Arbor, 48103 734 996-9200 http://www.surgitel.com

Swift Biosciences 58 Parkland Plz., Ste. 100 Ann Arbor, 48103 734 678-7689 http://swiftbiosci.com

Symmetry Jet 5212 Aurelius Rd. Lansing, 48911 517 882-4311 http://www.symmetrymedical.com

syncreon 2851 High Meadow Cir., Ste. 250 Auburn Hills, 48326 248 377 4700 http://www.syncreon.com

Systems Specialties 390 Enterprise Ct., Ste. 200 Bloomfield Hills, 48302 248 332-0099 http://www.sysspec.com

Takeda Pharmaceuticals North One Takeda Pkwy. Deerfield, IL, 60015 224 554-6500 http://www.tpna.com America, Inc.

Tangent Medical Technologies, LLC 2132 Packard St. Ann Arbor, 48104 734 330-2668 http://www.tangentmedical.com

TCH Pharmaceuticals, Inc. 300 N. Fifth Ave., Ste. 150 Ann Arbor, 48104 734 926-0966 N/A

Team Pharmaceutical Inc. 563 116th Ave. Martin, 49070 269 388-5708 N/A

Team Support Services P.O. Box 19536 Kalamazoo, 49019 269 226-0016 http://teamsupportservices.com

Tech Depot 6 Cambridge Dr. Trumbull, CT, 06611 203 615-7437 http://www.techdepot.com

Tech Initiatives Inc. 200 Michigan St., Ste. 408 Hancock, 49930 906 483-2676 http://www.cprmattress.com

Teclab 6450 Valley Industrial Dr. Kalamazoo, 49009 269 372-6000 http://www.teclab.com






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Tekna 3400 Tech Cir. Kalamazoo, 49008 269 978-3500 http://www.teknalink.com

Teresa M. Arnold & Associates 8300 Adler Rd. Lambertville, 48144 734 854-1187 http://www.tmaapr.com

Terumo Cardiovascular Systems 6200 Jackson Rd. Ann Arbor, 48103 734 663-4145 http://www.terumo-cvs.com

Terumo Heart, Inc. 6190 Jackson Rd. Ann Arbor, 48103 800 262-3304 http://www.terumoheart.com

Teter Orthotics & Prosthetics, Inc. 1225 W. Front St. Traverse City, 49684 231 947-5701 http://www.teterop.com

The Dow Chemical Company 2030 Dow Ctr. Midland, 48674 800 258-2436 http://www.dowventurecapital.com

The More Program 500 Griswold St., Ste. 3400 Detroit, 48226 313 223-2515 http://www.themoreprogram.com

The MRI Institute for Biomedical 440 E. Ferry St., Unit 2 Detroit, 48202 313 758-0065 http://www.mrimaging.com Research Imaging

The Project Group 7238 Windhaven Ct. Portage, 49024 269 321-0411 N/A

The Right Place, Inc. 161 Ottawa Ave. NW, Ste. 400 Grand Rapids, 49503 616 771-0325 http://www.rightplace.org

The Standing Company 5848 Dixie Hwy. Saginaw, 48601 800 782-6346 http://www.thestandingcompany.com

The Tech Group 3116 N. Wilson Ct. NW Walker, 49534 616 643-6001 http://www.techgroup.com

The Timberland Group 1707 W. Big Beaver Rd. Troy, 48084 800 695-2921 http://www.timberlandgroup.com

Therapeutics Systems Research 540 Avis Dr., Ste. A Ann Arbor, 48108 734 663-4233 http://www.tsrlinc.com Laboratories, Inc.

Therapy Charts LLC 228 Nickels Arcade Ann Arbor, 48104 866 288-9758 http://www.therapycharts.com

Thompson Surgical Instruments 10170 E. Cherry Bend Rd. Traverse City, 49684 231 922-0177 http://www.thompsonsurgical.com

Thomson Reuters 777 E. Eisenhower Pkwy. Ann Arbor, 48108 734 913-3000 http://www.thomsonreuters.com

Thorn Smith Laboratories 7755 Narrow Gauge Rd. Beulah, 49617 231 882-4672 http://www.thornsmithlabs.com

Thumb MRI Center, LLC 6320 Van Dyke Rd. Cass City, 48726 888 399-9469 http://www.thumbmri.com

Thumb Oilseed Producers 2145 Leppek Rd. Ubly, 48475 989 658-2344 http://www.thumboilseed.com

Tissue Regeneration Systems 401 W. Morgan Rd. Ann Arbor, 48108 N/A N/A

Tolera Therapeutics, Inc. 350 E. Michigan Ave., Ste. 205 Kalamazoo, 49007 269 585-2100 http://www.tolera.com

Topspins, Inc. P.O. Box 7205 Ann Arbor, 48107 734 623-6400 http://www.topspins.com

Tower Laboratories Montague 8060 Whitbeck Rd. Montague, 49437 231 893-1472 http://www.towerlabs.com

Toxicogenomic Informatics P.O. Box 27482 Lansing, 48909 N/A http://www.txisllc.com and Solutions, LLC

TransPharm Preclinical Solutions, LLC 7190 S. Brooklyn Rd. Jackson, 49201 517 536-8210 http://www.transpharmsite.com

Traxx Mobility Systems LLC 33750 Freedom Rd. Farmington, 48335 248 426-7700 http://www.traxxms.com

Trialon Corporation 5600 New King St., Ste. 345 Troy, 48098 248 641-1032 http://www.trialon.com

Trialynx, Inc. 2400 Frank Lloyd Wright Dr., Ste. H1200 Ann Arbor, 48105 734 930-4400 http://www.trialynx.com

Trossen HR Group 58 Parkland Plaza, Ste. 200 Ann Arbor, 48103 734 330-2588 http://www.trossenhr.com

Troy Biologicals, Inc. 1238 Rankin St. Troy, 48083 800 521-0445 http://www.troybio.com

Troy Polymers 330 E. Maple, Ste. L Troy, 48083 248 733-1030 http://www.troypolymers.com

Twin Bay Medical, Inc. 11590 US-31 S. Williamsburg, 49690 231 264-0101 http://www.barblock.com

Twinlab 3133 Orchard Vista Dr. SE Grand Rapids, 49546 616 464-5000 http://www.twinlab.com

Uckele Health and Nutrition P.O. Box 160 Blissfield, 49228 800 248-0330 http://www.uckele.com

Ultralight Prosthetics, Inc. 24781 Five Mile Rd. Redford, 48239 313 538-8500 http://www.ultralightprosthetics.com

Ultrasound Medical Devices, Inc. 3917 Research Park, Ste. B-7 Ann Arbor, 48108 734 369-5056 N/A

Unifab Corp. 3030 Kersten Ct. Kalamazoo, 49048 269 382-2803 http://www.unifabcages.com

United BioSource Corporation 2200 Commonwealth Blvd., Ste. 100 Ann Arbor, 48105 734 994-8940 http://www.unitedbiosource.com

Unival, Inc. 2311 Green Rd., Ste. D Ann Arbor, 48105 800 332-4463 http://www.unival-med.com

Universal Imaging 1159 E. Michigan Ave. Ypsilanti, 48198 734 528-0657 http://www.uimedical.com

University of Michigan 1301 E. Catherine Ann Arbor, 48109 734 764-1817 http://www.umich.edu

University of Michigan - A. Alfred 109 Zina Pitcher Pl., 5017 BSRB Ann Arbor, 48109 734 615-7282 http://www.med.umich.edu/taubmaninstitute Taubman Medical Research Institute

University of Michigan - 2200 Bonisteel Blvd. Ann Arbor, 48109 734 764-9588 http://www.bme.umich.edu Biomedical Engineering






61


University of Michigan - 1214 S. University Ave., 2nd Floor Ann Arbor, 48104 734 647-1000 http://www.bec.umich.edu Business Engagement Center

University of Michigan - 210 Washtenaw Ave., LSI Ann Arbor, 48109 734 763-1200 http://www.lsi.umich.edu Center for Chemical Genomics

University of Michigan - Palmer Commons Ann Arbor, 48109 734 615-5510 http://www.ccmb.med.umich.edu Center for Computational Medicine and Biology (CCMB)

University of Michigan - University of Michigan Dept. of Biomedical Ann Arbor, 48109 734 615-9412 http://www.bme.umich.edu/research/coulter.php Coulter Translational Research Engineering, 2200 Bonisteel Blvd., Partnership Program 1131 Gerstacker Bldg.

University of Michigan - Flint 2 E. 1st St. Flint, 48502 810 767-1863 http://www.umflint.edu

University of Michigan - 2215 Fuller Rd. Ann Arbor, 48105 734 936-4000 http://www.ann-arbor.med.va.gov Hospitals and Health Center

University of Michigan - 1000 Wall St. Ann Arbor, 48105 734 763-8122 http://www.kellogg.umich.edu Kellogg Eye Center

University of Michigan - 611 Church St., Rm. 240 Ann Arbor, 48104 734 647-4571 http://www.lss.sph.umich.edu Life Sciences & Society

University of Michigan - 210 Washtenaw Ave., 3rd Fl. Ann Arbor, 48109 734 763-1200 http://lis.umich.edu Life Sciences Institute

University of Michigan - 1301 Beal Ave. Ann Arbor, 48109 734 763-6719 http://lnf.umich.edu Lurie Nanofabrication Facility

University of Michigan - 24 Frank Lloyd Wright Dr., Ann Arbor, 48106 734 998-6994 http://www.med.umich.edu/ummic Medical Innovation Center Lobby M, Ste. 2600

University of Michigan - W. Medical Center Dr. Ann Arbor, 48109 734 764-8165 http://sitemaker.umich.edu/neubig.lab Medical School

University of Michigan - NCRC 2800 Plymouth Rd., Bldg. 520 Ann Arbor, 48109 734 764-7815 http://www.med.umich.edu/medschool/research Medical School Office of Research

University of Michigan - 24 Frank Lloyd Wright Dr., Lobby M Ann Arbor, 48106 734 998-7474 http://www.michr.umich.edu Michigan Institute for Clinical Health Research

University of Michigan - 2215 Fuller Rd. Ann Arbor, 48105 734 845-3056 https://sites.google.com/site/nanoscaleneurologylab Nanoscale Neurology Lab

University of Michigan - 1214 S. University, 2nd Fl. Ann Arbor, 48104 734 763-0614 http://www.techtransfer.umich.edu Office of Technology Transfer

University of Michigan - Office of 4080 Fleming Bldg., 503 Thompson Ann Arbor, 48109 734 764-1185 http://www.research.umich.edu the Vice President for Research

University of Michigan - 701 Tappan St. Ann Arbor, 48109 734 764-1363 http://www.bus.umich.edu Ross School of Business

University of Michigan - Robert H. Lurie Engineering Center, Ann Arbor, 48109 734 647-7000 http://www.engin.umich.edu School of Engineering 1221 Beal St.

UPS 2960 Lucerne Dr. SE Grand Rapids, 49546 734 347-2451 http://www.ups.com

Urobiologics LLC 31628 Glendale Ave. Livonia, 48150 313 574-7500 http://www.urobiologics.com

VA Medical Center - Ann Arbor 2215 Fuller Rd. Ann Arbor, 48105 734 930-5100 http://www.hsrd.ann-arbor.med.va.gov

Validation & Compliance Institute, LLC 1529 Boxford Rd. Trenton, 48183 734 274-4680 http://www.vcillc.com

Van Andel Institute 333 Bostwick Ave. NE Grand Rapids, 49503 616 234-5000 http://www.vai.org

Van Beek Nutrition 3537 W. YZ Ave. Schoolcraft, 49087 269 679-5441 http://www.vanbeeknutrition.com

Velcura Therapeutics, Inc. 4300 Varsity Dr., Ste. D Ann Arbor, 48108 734 973-1000 http://www.velcura.com

Velesco Pharmaceutical Services 46701 N. Commerce Center Dr., Ste. A8 Plymouth, 48170 734 545-0696 http://www.velescopharma.com

Venture Technology Groups 23800 Industrial Park Dr. Farmington Hills, 48335 248 473-8450 http://www.venturegroups.com

Versus Technology, Inc. 2600 Miller Creek Dr. Traverse City, 49684 231 946-5868 http://www.versustech.com

Vertellus Health and Specialty 215 North Centennial St. Zeeland, 49464 800 223-0453 http://www.vertellus.com Products, LLC

Vestaron Corporation 4717 Campus Dr., Ste. 1200 Kalamazoo, 49008 269 372-3108 http://www.vestaron.com

VetGen, LLC 3728 Plaza Dr., Ste. 1 Ann Arbor, 48108 734 669-8440 http://www.vetgen.com

ViaDerm, LLC 300 River Pl., Ste. 6850 Detroit, 48207 313 446-2800 N/A

Vigor Therapy Solutions 4915 Advance Way Stevensville, 49127 800 597-6566 http://www.vigorequipment.com

VO2 Ventures LLC 30375 Northwestern Hwy. Farmington Hills, 48344 248 358-3956 http://www.vo2ventures.com





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Vortech Pharmaceuticals 6851 Chase Rd. Dearborn, 48126 313 584-4088 http://www.vortechpharm.com

VWR International 4906 Gullane Dr. Ann Arbor, 48103 800 932-5000 http://www.vwr.com

W.F. Valentine & Co. 7633 Quackenbush Reading, 49274 517 283-3143 http://www.wfvalentine.com

Wacker Chemical Corporation 3301 Sutton Rd. Adrian, 49221 888 922-5374 http://www.wacker.com

Warde Medical Laboratory 300 W. Textile Rd. Ann Arbor, 48108 734 214-0300 http://www.wardelab.com

Warner Norcross & Judd LLP 900 Fifth Third Center, 111 Lyon St. NW Grand Rapids, 49503 616 752-2169 https://www.wnj.com

Wayne State University Anthony Wayne Dr. Detroit, 48202 313 577-2424 http://www.wayne.edu

Wayne State University - 540 E. Canfield, Scott Hall, Rm. 3127 Detroit, 48201 313 577-5323 Center for Molecular Medicine http://www.genetics.wayne.edu/Education/phd_program_description.htm & Genetics

Wayne State University - 259 Mack Ave. Detroit, 48201 313 577-1384 http://www.wayne.edu College of Pharmacy & Health Science

Wayne State University - 3172 Engineering Bldg., Detroit, 48202 313 577-1306 http://www.ssim.eng.wayne.edu/cleanroom Smart Sensor and Integrated 5050 Anthony Wayne Dr. Microsystems

Wayne State University - 440 Burroughs, Ste. 201 Detroit, 48202 313 577-1345 http://www.techtransfer.wayne.edu Technology Commercialization

Wayne State University - TechTown 440 Burroughs - Entrepreneurial Suite Detroit, 48202 313 879-5250 http://www.techtownwsu.org/index.htm

Wayne State University Applied WSU C.S. Mott Center, 275 E. Hancock Detroit, 48201 313 577-6200 http://agtc.wayne.edu Genomic Technologies - Center for Technology Excellence

WelchDry, Inc. 4270 Sunnyside Dr. Holland, 49424 616 399-2711 http://www.welchdry.com

Wellness Indicators Inc. N25 W23050 Paul Rd. Pewaukee, WI, 53072 414 243-4178 http://www.wellnessindicators.com

West Michigan Regional Laboratory 1726 Knollcrest Cir. SE Grand Rapids, 49546 616 526-8440 http://www.calvin.edu/admin/wmrl

West Michigan Science and 301 Michigan St. NE, Ste. 537, Grand Rapids, 49503 616 331-5840 http://www.wmsti.org Technology Initiative Cook - DeVos Center for Health Sciences, Grand Valley State University

Western Michigan University Office of the Vice President for Research, Kalamazoo, 49008 269 387-1000 http://www.wmich.edu 1903 W. Michigan Ave.

Western Slope Laboratory 1197 Rochester Rd., Ste. K Troy, 48083 248 307-1168 http://www.westernslopelabs.com

Williams Syndrome Association P.O. Box 297 Clawson, 48017 248 244-2229 http://www.williams-syndrome.org

Wizard Med LLC 48223 Chesterfield Canton, 48187 734 536-1602 http://www.wizardmed.com

Working Bugs, LLC 16647 Chandler Rd. East Lansing, 48823 517 203-4744 http://www.workingbugs.com

Wright & Filippis, Inc. 2845 Crooks Rd. Rochester Hills, 48309 248 829-8292 http://www.firsttoserve.com

XB Transmed Solutions 3133 Orchard Vista Dr. SE Grand Rapids, 49546 616 234-5586 http://www.xbtransmed.com

XG Sciences, Inc. 815 Terminal Rd. Lansing, 48906 517 703-1110 http://www.xgsciences.com

Xoran Technologies, Inc. 5210 S. State Rd. Ann Arbor, 48108 800 709-6726 http://www.xorantech.com

X-Rite 4300 44th St. SE Grand Rapids, 49512 616 257-2203 http://www.xrite.com

YourSurgery.com 7171 First St. West Bloomfield, 48324 248 858-2606 http://www.yoursurgery.com

ZDR, Inc. 7300 Whitmore Lake Rd. Brighton, 48116 810 231-6600 http://www.zdr.com

zuSyn 4717 Campus Dr., Ste. 100 Kalamazoo, 49008 312 997-2150 http://www.zusyn.com




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