biomatters - spring 2010

In This Issue:

2010 Michigan Biosciences Directory and Resource Guide

Venture Capital Stacking Up

for Michigan’s BioscienceCompanies

BioMattersA MichBio Publication Showcasing Michigan’s Biosciences Industry

S P R I N G 2 0 1 0

Also Featured:

Engaging Michigan’s Young Scientists: Innovative Programs

that Make Science “Cool”

State Legislators on Leading Edge in Bioscience Focus

BioMatters | Spring 20101

Dear Innovators:

A strong, thriving biosciences industry is a vital part of our ongoing efforts to diversify Michigan’s economy. I am inspired by the innovations of our 525-plus biotech companies and delighted that they are pushing ahead with investments, expansions, and new job creation. Major bio-corporations, Stryker and Perrigo, are thriving. MPI Research is on track to open its downtown Kalamazoo laboratories this year. And Detroit will host the 2010 World Stem Cell Summit in October. All of this activity represents meaningful growth ahead for the life sciences in Michigan. Michigan offers everything necessary for a strong and growing biotech industry, including and most importantly, a broad and deep pool of technical talent. The Southwest Michigan Innovation Center has launched more than two dozen life sciences companies so far. We are assured of more as Michigan’s aggressive initiatives — investments totaling more than half a billion dollars in services, commercialization resources, and facilities — support our entrepreneurs and nurture tech startups. Our base of expert life-sciences professionals is backed by a world-class university research apparatus that acts as a catalyst for bio-innovation. In Ann Arbor, the two-million-square-foot former Pfizer facility acquired by the University of Michigan (U of M), has identified the first core technology areas at what is now called the North Campus Research Complex, including nanotechnology, molecular imaging, and drug delivery. The site will also house research in clean energy to enable future collabora-tions in biofuels. In Detroit, Wayne State University’s TechTown, one of Michigan’s 15 SmartZone technology clusters, is overflowing with 165 small businesses and planning to quadruple the business incubator’s space. Human tissue bio-repository Asterand plc, now publicly traded on the London Stock Exchange, was TechTown’s first tenant a decade ago. We see progress, too, in the availability of capital for our emerging biotechs. Michigan is home to 16 venture capital funds, and one of only nine states to offer state fund-of-fund investment programs. Recent successes include U of M spinoffs NanoBio, HealthMedia, and HandyLab. We will continue to grow Michigan’s biotechnology sector as part of our aggressive efforts to diversify the state’s economy. Commercialization activities, venture capital, and other growth opportunities created by our targeted initiatives ensure that Michigan will continue as an innovative and increasingly important life sciences center well into the future.

Jennifer M. Granholm, Governor of Michigan

G O v e R N O R ’ S M e S S A G e

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Michigan’s Biosciences Industry Welcomes You! Michigan is home to a strong biosciences industry with a rich legacy that originated

with the likes of Parke-Davis Pharmaceuticals (the first U.S. based pharmaceutical

company), the Upjohn Company, Stryker and Perrigo. Today, the state’s biosciences

community consists of almost 41,000 talented and skilled employees found in over 525

companies and institutions, coupled with another 58,000 spinoff jobs. They cover

the breadth of pharma/biotech, medical devices/equipment, research products and

diagnostics, informatics, ag-bio, bio-defense, bio-environmental, industrial biotechnology,

testing/medical laboratories and clinical research.

What best defines Michigan’s biosciences industry? In a word — success! Over the last

eight years our bioscience companies have achieved a remarkable track record of invest-

ment, growth, and return. We’ve seen more than 120 companies launched largely through

$323 million of State of Michigan support, as well as an additional $46 million of investment

by the state’s fund-to-funds that were directed to biotech start-ups. Capital investment

under management in Michigan’s emerging companies exceeded $1 billion last year.

More importantly, Michigan bio-companies have realized numerous successful exits

such as Esperion Therapeutics ($1.4 billion purchase by Pfizer in 2004), Lumigen (acquired

by Beckman Coulter in 2008), HealthMedia (bought by Johnson & Johnson in early 2009),

and HandyLab (purchased by Becton Dickinson in late 2009). In addition, various emerging

biotech companies including Accuri Cytometers, NanoBio, Lycera, and HistoSonics have

procured large venture capital investments during the same period. The bottom line is

that ‘success breeds success’ when it comes to Michigan’s biosciences industry.

In this issue of BioMatters you’ll read about the many resources, programs, incentives

and infrastructure available to bioscience companies for their launch and growth. Whether

you’re already here in our gorgeous state where the cost of living and doing business is

low and the bio-talent is readily available, or looking from outside our borders to expand,

Michigan has everything to offer and your company to gain. Simply contact me at

[email protected] and let MichBio, the state’s bioscience industry association show

you how to access the information, resources and assistance needed to make your venture

a success here in Michigan.

Stephen Rapundalo, Ph.D.

President and CEO, MichBio

P R e S I D e N T ’ S M e S S A G e

P R O F e S S I O N A L S TA F F

C O N TA C T I N F O R M AT I O N

Stephen T. Rapundalo, Ph.D.

President and CEO

[email protected]

734.527.9144

Jayne Berkaw

Director,

Marketing and Communications

[email protected]

734.527.9147

Heather Kusiak

Manager,

Operations and Membership

[email protected]

734.527.9150

Nancy Marcotte

Manager, Finance

[email protected]

734.527.9145

Physical Address

3520 Green Court, Suite 450

Ann Arbor, Michigan 48105-1579

Mailing Address

P.O. Box 130199

Ann Arbor, Michigan 48113-0199

Phone

734.527.9150

Fax

734.302.4933

Website

www.michbio.org

General Information

[email protected]

Check out Digital BioMattersNext Issue: FALL 2010 BioMatters is now available in digital and print formats. Digital BioMatters is click-able, magnifiable, printable, linkable, savable and sendable, and it offers advertisers an array of tools that are not available in print. These include:

• Direct links to your website and email addresses

• The ability to include customizable forms so readers can request more information

• The ability to include interactive media and video content

• expanded reach to a broader distribution list

Digital BioMatters is distributed to MichBio’s database of 7,000 targeted emailaddresses, and it is always available on the MichBio website (www.michbio.org). Be sure to pass it along to your own customers and constituents, and help us spread the word about Michigan’s robust biosciences industry.

BioMatters | Spring 2010 4

CORPORATe SPONSORS

P L AT I N U M

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Lumigen, Varnum

FRIeNDPhadia US, Inc.,

Wayne State University

SUPPORTERBiotechnology Business

Consultants, Caraco,sanofi-aventis U.S.,

West Michigan Science & Technology Initiative

M e D I A

ExECUTIvE OffICERSChairmanStephen Munk, Ph.D.Ash Stevens, President and CEO

President and CEOStephen T. Rapundalo, Ph.D.MichBio, President and CEO

Secretary Christina DeHayesAsterand plc, General Counsel

Treasurer Matthew L. McCollErnst & Young LLP, Partner

Assistant TreasurerRyan Noel Division of Metabolism, Endocrinology and Diabetes, University of Michigan Administrator

DIReCTORSLinda Chamberlain, Ph.D.West Michigan Science &Technology InitiativeExecutive Director

David Felten, M.D., Ph.D.Beaumont Hospitals, Research InstituteVice President, Research and Medical Director

J. Patrick ElliottTerumo Cardiovascular Systems Corp.Vice President, Business Development

James Freeman, Ph.D.Pfizer Animal HealthVice President, Laboratory Sciences

Ricardo (Richard) Fuentes Jr.Dow Corporate Venture CapitalGlobal Life Science Investment Director

Teri GriebU of M Medical School, Office of ResearchDirector of Administration for ResearchOffice of Research and Graduate Studies

Mark KielbAltarum InstituteChief Financial Officer

Barry KleinGlaxoSmithKlineDirector, Market Development

Michael Kurek, Ph.D.Biotechnology Business ConsultantsPartner/President

Paul MorrisAlixPartners, LLP Finance Manager, National Enterprise Improvement Practice

Stephen Munk, Ph.D.Ash Stevens, President and CEO

Stephen T. Rapundalo, Ph.D.MichBio, President and CEO

John J.H. Schwarz, M.D.Family Health CenterPhysician,Former U.S. Representative

Eric StiefWayne State University — Technology CommercializationLicensing Manager Director of Venture Development

Karen Studer-RabelerCoy Manufacturing/Coy Laboratory ProductsGeneral ManagerVice President, Business Development

David ZimmermannKalexsyn, Inc.Chief Executive Officer

COMMITTeeSFacilitiesIntellectual Properties and LegislationMarketing and CommunicationsMembership and ServicesProgramsPublic Policy

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BioMattersT A B L e O F C O N T e N T S

A D v e R T I S e R S

Ann Arbor SPARK ................................................. 12Ash Stevens ............................................................. 46 Bank of Ann Arbor ................................................. 24Calibrate .................................................................. 42 DBA Analytical ........................................................ 41Doeren Mayhew ...................................................... 18Dykema ................................................................... 42Great Lakes Entrepreneur’s Quest ......................... 24Golden Limo ........................................................... 46Grand Valley State University ................................. 24Healthmark ............................................................. 46

PhRMA .................................................................... 68Plas Labs ................................................................ IFCRadar Fishman & Grauer ...................................... 31RS Electronics ........................................................ 33The Brooks Industrial Park ...................................... 2 University of Michigan .......................................... 30Varnum Law ............................................................ 33 Wayne State University ........................................... 36West Michigan Science & Technology Initiative ......5 Western Michigan University ................................. 41

Hylant Group ........................................................... 31Kettering University ............................................... 19Michigan Economic Development Corporation ... IBCMichBio ................................................................. BCMichigan State University ...................................... 21Microbiological Associates .................................... 42Midwest Cleanrooms ............................................. 46MPI Research ......................................................... 27NuStep .................................................................... 31Oakland University ................................................. 33Pfizer .......................................................................... 6

4 MichBio Corporate Sponsors, Officers, Directors and Committees

13 Investor Sees Potential Growing for VC Backing of Michigan Bio Projects

Feature StOry: Venture Capital Support for Bioscience Grows in Michigan

20Michigan to Host World Stem Cell Summit

17

34

ecotek Shows Students the “World” of Science

Michigan House and Senate appoint Legislative Groups to Focus on the Bioscience Industry

25 eNtrePreNeurS: entrepreneurship Thrives in Michigan

The following MichBio members are featured in this issue of BioMatters:Accuri Cytometers, Ann Arbor SPARK, Apjohn Group, Arboretum Ventures, Asterand, Borgess Medical Center, ClinXus, Coy Laboratory Products, Esperion Therapeutics, CytoPherx, EXT Life Sciences,

Global Clinical Connections, Grand Valley State University, Housey Pharmaceuticals, Hylant Group, Johnson & Johnson, Kalexsyn, Karmanos Cancer Center, Lumigen, Metabolic Solutions Development, Michigan Economic Development Corporation, Michigan State University, Molecular Innovations, Monteris, MPI Research, Oakland County Medical Main Street, Micromyx, NanoBio Corporation,

NanoSystems, Oxford Biomedical Research, Pfizer, QuatRx Pharmaceuticals, Quest Research Institute, RealBio Technology, Southwest Michigan First, Southwest Michigan Innovation Center, Southwest Michigan Life Science Fund, TechTown, Terumo Cardiovascular Systems, University of Michigan, Van Andel Institute, Vesteron, Wayne State University.

Subscribe to BioMatters:Visit www.michbio.org and click “register Now” or call 734.527.9150.

14eDuCatION: Students Thrive in Michigan Science education Programs

26Bioarbor Gives entrepreneurs a Place to Network and Learn

45 GueSt OPINION: academic- Industry Partnerships: reaching Out, reaching In

38eCONOMIC DeVeLOPMeNt: The Five Fingers of Michigan’s “upper Hand” advantage

Southwest Michigan First

MedicalMain Street

Ann ArborSPARK

TechTown

The Right Place

32PrOFILe: Neogen Plots Course for Continued Success in Food, animal Safety Industry

44What’s So Good about Doing Bio-Business in Michigan?

8

29 Innovator of the year Finds renewable resources to replace Petroleum-Based Products

47DIreCtOry & reSOurCe GuIDe

37Clinical trials tax Credit Could Benefit Michigan Labs

39 Kalamazoo Makes Sense for Seneca Medical

FINANCIAL MATTeRS fEATURE STORY

8BioMatters | Spring 2010

Venture Capital Support for Bioscience

Grows in Michigan


After years in the minor leagues, Michigan

is becoming a popular destination for venture

capital as firms acknowledge the state’s

robust university research community, its

highly skilled workforce, and especially,

its track record in the bioscience sector.

“Michigan’s been making some progress

over the last years,” says LeAnn Auer, execu-

tive director of the Michigan Venture Capital

Association. “We started in 2001 with seven

venture capital firms headquartered here

and now we have 16. The amount of capital

under management is now over $1 billion,

twice as much as in 2001.”

Auer says California and Massachu-

setts traditionally claim 60 percent of the

country’s available venture funding, but

Michigan is making impressive strides. In

terms of the total amount of venture capital

invested in the state, Michigan ranked 14th

in 2008, up from 25th in 2007.

The MVCA says $1.3 billion in demand

for venture capital funding existed in Michi-

gan in 2008, and of the 14 Michigan-based

firms, 12 invest in life science fields. “If you

The recipe for economic growth and innovation often calls for a heaping portion of venture capital, dollars put up by investment firms whose job is to search out The Next Big Thing, nurture it, guide it, and hopefully eventually profit from it. One of every 10 jobs in the U.S. was created from either a currently or previously venture-backed

company, and those firms represent 19 percent of the country’s gross domestic product.

break down that $1.3 billion, half of it came

out of biotechnology, medical technology,

and healthcare services,” says Auer.

100:1 RATIO The courtship between venture capital-

ists and entrepreneurs involves a complex

mating dance that often results in the ven-

ture being rejected. Chris Rizik, who runs

the $40 million Renaissance Venture Capital

Fund at Ardesta LLC in Ann Arbor, says a VC

firm typically looks at 100 prospects before

it is convinced to open its wallet. There are

some obvious traits, however, that make a

firm attractive to investors.

“You certainly look for a company that

is going to fulfill a need out there that isn’t

currently being met,” says Rizik. He points

to Ann Arbor-based HealthMedia, Inc.,

a University of Michigan spin-off whose

Web-based health coaching technology

helps companies lower healthcare costs and

improve wellness. HealthMedia opened its

doors in 1998 with support from VC firms in

Kentucky and Michigan, and was acquired

by Johnson & Johnson in 2008 for an undis-

closed sum.

For Michael Gross, managing direc-

tor at Beringea LLC in Farmington Hills,

whose $100 million InvestMichigan! Growth

Capital Fund portfolio includes Accuri

Cytometers and Pioneer Surgical Technol-

ogy, Inc., key factors include the size of the

market opportunity, the differentiation of

the product or service, and the experience of

the management team. “We like to see entre-

preneurs who are experienced in the space

in which they’re building their company

and ideally have a track record of building

previous companies,” Gross says.

HANDYLAB MEETS THE NEED Jeff Williams, a prominent Michigan

entrepreneur who has held executive posts

in Genomic Solutions, Inc. and HandyLab,

Inc., and is currently president and CEO of

Accuri Cytometers, Inc., says he looks for

evolutionary technology that solves a major

unmet need, but is not so radical that it

takes a long time to adopt. He found that

formula in HandyLab, Inc., an Ann Arbor-

based clinical diagnostics company that

was founded in 2000 by two University of

Michigan Ph.D. candidates.

By Tom Beaman

Michigan is becoming a popular destination for venture capital as firms acknowledge the state’s robust university research community, its highly skilled workforce, and especially, its track record in the bioscience sector.

$1.3 billion in demand for venture capital funding existed in Michigan in 2008—half of it came out of biotechnology, medical technology, and healthcare services

Venture-backed HealtHMedia, inc., a uniVersity of MicHigan spin off, proVides Web-based HealtH coacHing tecHnology. tHe coMpany Was acquired by JoHnson & JoHnson in 2008.


“HandyLab’s technology uses nucleic acid

amplification to test for infectious diseases like

influenza, STD’s and MRSA,” says Williams,

who joined the company in 2004. “Their tech-

nology enables you to do that faster with

a fully automated, compact system that’s easy

to use. Hospitals can run tests themselves and

get the results much more rapidly.”

After beginning life in 2000, with over

$40 million in backing from several venture

capital firms and Pfizer, Inc., HandyLab was

acquired by Becton Dickinson and Company

in 2009 for $275 million.

Sometimes it’s whom you know as much

as what you know that results in a success-

ful marriage in the biotech world. In 2006,

Daniel H. Farkas, Ph.D., HCLD, a nationally

recognized leader in the field of molecular

diagnostics, was hired to run the Center

for Molecular Medicine, a joint venture of

Spectrum Health and the Van Andel Institute

in Grand Rapids.

PUTTING GRAND RAPIDS ON THE MAP“I didn’t want to come to Grand Rapids just

to build another Chlamydia lab,” says Farkas,

who has established DNA diagnostics facili-

ties in New Jersey, Michigan and Texas. “I

came here to take advantage of my network

in both biotech and molecular diagnostics

to help put Grand Rapids on the map for

biotechnology.”

Farkas’s strategy was to leverage the

city’s already impressive medical establish-

ment, which included the Fred and Lena

Meijer Heart Center and the Lemmen-Holton

Cancer Pavilion, to attract additional invest-

ment to the region. “We have an outstanding

research facility in the Van Andel Institute

and a magnificent healthcare system

embodied in Spectrum Health. They were

interested in bringing new jobs and oppor-

tunities to town,” he says.

Mining his considerable professional net-

work with the fervor of a civic leader (“Just

come here and take a look,” Farkas would tell

skeptical colleagues.), he sang the region’s

praises. “We got Canon, Qiagen, and Siemens

to show up,” he says. “We got the attention

fEATURE STORY

“I came here to take advantage of my network in both biotech and molecular diagnostics to help put Grand Rapids on the map for biotechnology.”

tHe center for Molecular Medicine in grand rapids Was originally a Joint Venture of spectruM HealtH and tHe Van andel institute. tHe coMpany Was acquired by sequenoM in 2008.

Michigan-BaSed BiO-FOcUSed VENTURE CAPITAL FIRMS n Apjohn Group, LLC – www.apjohnventures.com

n Arbor Partners – www.arborpartners.com

n Arboretum ventures – www.arboretumvc.com

n Ardesta, LLC – www.ardesta.com

n Beringea – www.beringea.com

n BioStar ventures – www.biostarfund.com

n Bridge Street Capital - www.bridgestreetcapital.com

n eDF ventures – www.edfvc.com

n North Coast Technology Investors – www.northcoastvc.com

n Oracle Capital Partners - www.oracle-capital.com

n Plymouth Management Company - www.plymouthvc.com

n Renaissance venture Capital Fund - www.renvcf.com

n Seneca Partners – www.senecapartners.com

n Southwest Michigan First Life Science Fund – www.southwestmichiganfirst.com

n TGap ventures – www.tgapventures.com

n Wolverine venture Fund – www.zli.bus.umich.edu/wvf

VENTURE FIRMSwith FUll-OR PaRt-tiMe STAFF IN MICHIGAN n Chrysalis ventures - www.chrysalisventures.com

n early Stage Partners - www.esplp.com

n fletcher Spaght - www.fletcherspaght.com

n Triathlon Medical venture Partners - www.tmvp.com

n venture Investors - www.ventureinvestors.com

tHe nuMber of Venture capital firMs Headquartered in MicHigan Has doubled since 2001, according to leann auer, executiVe director, MicHigan Venture capital assoc.


of a lot of folks, including Sequenom, who

knocked on my door in July 2008 and said,

‘We want to buy your lab.’” The $4 million

deal was finalized in November 2008.

When the purchase was announced,

David Van Andel, chairman and chief

executive officer of the

Van Andel Institute, said,

“Sequenom and the Van

Andel Research Institute

have a shared vision – to

move important scientific

findings from research

laboratory to clinical

laboratory to patients.

CMM was created to

leverage new technolo-

gies for the purposes of

more precise treatment

options for patients and,

through this acquisition

by Sequenom, and our

research collaboration,

this goal can be realized

more immediately.”

Farkas has high hopes for Michigan,

which he says he loves. “We have a lot of

the tools and raw materials that can attract

biotech companies to this region,” he says.

“Commercial real estate is cheap, we have a

lot of skilled engineering and manufacturing

labor, and we have a lot of intellectual capital

in our universities. We are definitely on the

map and should be noticed by those who

are interested in investing in biotech.”

“We have a lot of the tools and raw materials that can attract biotech companies to this region.”

dan farkas’ ferVor for tHe grand rapids region and His center for Molecular Medicine is infectious. it attracted sequenoM to tHe region, bringing Jobs and inVestMent into tHe coMMunity.

“we are definitely on the map and should be noticed by those who are interested in investing in biotech.”

Dan Farkas, Sequenom Center for Molecular Medicine.

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I also call it home. The place where my company can thrive and expand. And the place where start-ups have every advantage. That includes superb laboratory space. A long list of business amenities. And—perhaps most important— peer-to-peer mentoring that connects them with experienced entrepreneurs on a daily basis.

An incubator in a state-of-the-art facility... where innovation thrives!”

Roger Newton, President & CEO,Esperion Therapeutics, Inc.

The Michigan Life Scienceand Innovation Center (MLSIC)n State-of-the-art wet labsn Spacious officesn Early-stage supportive testing facilityn Conference roomsn Cubicle spacen Video conference accessn Kitchen and cafeterian Loading dockn Mailing, shipping, receiving servicesn VOIP phone servicen T-1 Internet connectionn Monitored securityn Wireless Internetn Ample parkingn Fitness Center

Have a business idea or looking to expand your enterprise? Contact Greg Fronizer, at 734.761.9137 or [email protected].

“

The Michigan Life Science and Innovation Center. For start-ups, it doesn’t get any better than this.”

“

MLSICSoutheast Michigan’s New Home for Innovation-Based Business

46701 Commerce Center Drive Plymouth, Michigan 48170www.mlsic.com www.annarborusa.com

Investor Sees Potential Growing for VC Backing of Michigan Bio Projects

BioMatters | Fall 200913

fletcher Spaght ventures (fSv) is looking for a few good

companies. The Boston-based venture capital fund has been

scouring the entrepreneurial landscape for nine years, dip-

ping into its $100 million-plus pool of cash when it discovers

a promising start-up. The firm specializes in emerging high

technology and healthcare companies and has backed start-

ups from Massachusetts to California, but it also sees Michigan

as fertile ground for its investment dollars.

“The potential for Michigan is there, that’s for sure,” says

John fletcher, the founding partner of fSv. “In the last four

to five years, at least half of the companies that have been

funded by venture capital in Michigan have been in biotech,

medical devices, equipment, and healthcare services.”

Fletcher says Michigan ranks highly in many categories,

and this suggests enormous potential. The state is fifth in the

number of patents awarded, eleventh in National Institutes of

Health funding, second in industrial R&D spending, and ninth

in government research funding.

“What this says is that there is a lot of money going into high

quality research and development in life sciences in the state

of Michigan,” he adds.

Fletcher Spaght ventures, along with three other venture

capital firms, invested $11 million in HistoSonics Inc., an Ann

Arbor-based start-up whose histotripsy technology, which

uses focused sound waves to non-invasively break up tumors

and unwanted lesions, was developed in laboratories at the

University of Michigan. The first clinical application of histo-

tripsy will be the treatment of benign prostate hyperplasia,

and it’s expected to revolutionize ultrasound therapy.

Though a relative newcomer to the industry, HistoSonics

“has a CeO, a medical advisory board, a product development

team, and they’re creating jobs,” says Fletcher.

Despite its impressive track record to date, Michigan still

trails life science megaplayers like California. It ranks twenty-

second in total venture capital invested and thirty-eighth in

venture capital invested per patent awarded. But Fletcher

says given time and the proper support, Michigan can compete

with any state, or even countries like Ireland, which boasts a

thriving bioscience industry that employs 40,000 people.

“It takes some time to build up a critical mass in all of

these centers of expertise, but it can be done,” says Fletcher.

“Michigan’s on the front end of that process and doing an ex-

cellent job. The state has launched many innovative programs

that are fundamental to building a strong venture capital com-

munity. The benefits could be tremendous.”

The potential for Michigan is there, that’s for sure,” says John fletcher, the founding partner of FSv.

The state is fifth in the number of patents awarded, eleventh in National Institutes of Health funding, second in industrial R&D spending, and ninth in government research funding.

fEATURE STORY


EDUCATION

Students Thrive in Michigan Science Education

Programs

By Tom Beaman

The country’s educational infrastructure faces tremendous hurdles, but amidst the challenges there is cause for hope,

especially for students aiming for a career in the biosciences, starting right here in Michigan.

“There is an increased rigor in science

courses with the new Michigan state curricu-

lum,” says Robby Cramer, executive director

of the Michigan Science Teachers Association

and science education specialist with the Van

Andel Education Institute (VAEI) in Grand

Rapids. “All students must take biology in

high school...and they must have at least

three years of science in high school.”

Cramer sees more students taking

advanced placement biology courses, and she

is encouraged by the results. “Michigan is six

percentage points above the national average

and ranks ninth in the nation in the number

of students passing AP science courses with a

score of three or higher. In AP biology courses

we are ranked tenth in the nation.”

MichBio President and CEO Stephen

Rapundalo, Ph.D., agrees, but is pushing for

more: “Across the board, there has been a

higher level of achievement in the sciences,

but I think we have to do more to expose kids

to hands-on experience in biotechnology,” he

says. “It ties scientific theory to the real world

in a way that they can better understand. And

the more they can relate with, the more they

appreciate the diversity of career paths and

opportunities possible in the biosciences.”

SUCCESS = ENGAGED Rapundalo is not alone in his beliefs. If

educators in Michigan agree on anything,

it’s that science education – and the resulting

igniting of passion for the sciences in young

minds – will only succeed if kids get a taste

of the real thing. The word most often heard

during these discussions is “engaged.”

A soon-to-be-published study by the

Van Andel Institute indicates that 80 percent

of elementary students are excited by

science, but by the time they reach middle

school and high school, two thirds have

lost interest. “We believe...they’ve lost their

motivation to study science, in part, because

they haven’t engaged in it,” says Marcia

Bishop, associate director of the Van Andel

Education Institute.

If educators in Michigan agree on anything, it’s that science education – and the result-ing igniting of passion for the sciences in young minds – will only succeed if kids get a taste of the real thing.

17 BioMatters | Spring 2010BioMatters | Spring 201015

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at tHe MacoMb MatHeMatical science and tecHnical center in arMada, students participate in a year-long researcH proJect tHat culMinates WitH a presentation before tHe WHole scHool during WHicH tHey Must defend tHeir Work.


“In classrooms where students are

engaged actively in doing science, science

is cool,” says Paul Drummond, science

consultant and co-director of the Macomb

Mathematics Science and Technical Center

in the Macomb Intermediate School District.

But before students can be engaged,

teachers must be engaged, and that’s easier

said than done. Bishop cites recent Van

Andel and National Science Foundation

studies that found that elementary school

teachers feel unqualified to teach science

due to a professional development focus on

math and language arts; the lack of time,

resources, or space; or insufficient science

training in college.

THREE YEARS, 300 HOURS In an effort to sharpen science teacher

qualifications, the VAEI offers the “Part-

ners for Sustainable Innovation” program

through its Science Academy. The program

partners middle school teachers from the

Grand Rapids area with life science profes-

sionals at hospitals and universities. Over

a three-year period, teachers receive 300

hours of professional development aimed at

deepening their understanding of scientific

concepts, health and life science careers, and

the use of inquiry-based learning to engage

students in science.

“[The program] will not only improve the

effectiveness of science teachers to educate

the future life sciences workforce, but will

also spark student interest in science, leading

more of them to science-related careers,”

says Bishop.

Another Science Academy offering, the

“Out-of-School-Time Cohort Program,”

teaches fourth and fifth graders to think and

act like scientists. For three consecutive years,

Grand Rapids-area students conduct research

based on hypotheses, work in teams, record

data in lab books, and report their findings

to each other and larger audiences.

“Students in all of our programs are

actively engaged in questioning, predicting,

observing, evaluating, explaining, and mak-

ing claims based on the evidence they found,”

says Bishop. “The critical component is that

they see themselves as scientists.”

“VALUE OUTSIDE THE SCIENCES” Students are being turned on to biosci-

ence on the other side of the state as well. At

the Macomb Academy of Arts and Sciences

in Armada, Michigan, some 200 students

spend four intensive years studying calculus,

computer science, forensics, and biology, all

at honors levels.

“Our big activity is a yearlong research

project,” explains Ron Blume, a science

teacher at the school which is known by its

exponential acronym MA2S. “We analyze the

data for a month, and then we start them on

the process of writing a scientific paper. They

create a presentation and they have to defend

their work in front of the whole school.”

Among the student research projects

produced at MA2S in 2009 were “The Effect

of Antimicrobial Content in Polyethylene

on the Prevention of Bacterial Growth” and

“The Effect of Hydrogen Peroxide on the

Immunity of Escherichia Coli.”

“The feedback we’ve received from kids

who’ve gone off to college, regardless of

whether they’ve entered the science field,

a critical coMponent of science education prograMs at tHe Van andel education institute in grand rapids is tHat tHe students see tHeMselVes as scientists conducting researcH, Working in teaMs, recording data and reporting tHeir findings.

“The feedback we’ve received from kids who’ve gone off to college, regardless of whether they’ve entered the science field, was that [their research project] was one of the most valuable things that they did”

EDUCATION

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19 BioMatters | Spring 2010

Amber Young has done research on aortic aneurysms,

traveled to South Africa to study climate change, and met

with members of the United Nations’ World Health Organi-

zation to discuss ways to improve access to healthcare

and prevent common illnesses that arise from unsanitary

conditions.

Amber Young is 11, and in the sixth grade.

Amber, who attends the Detroit edison Public School

Academy, is also one of 15 “student scientists” currently

enrolled at Ecotek, a branch of the Motor City Model U.N.

Club, whose aim is to give students a better understanding

of the way science shapes international policymaking. From

its labs in Detroit’s TechTown business incubator, ecotek stu-

dents get a deep-dive, hands-on experience with some of the

hottest scientific topics: environmental science, alternative

energy, molecular/material science, and biotechnology.

With guidance from Ecotek founder Keith Young and

visiting guest scientists, the students, who range in age from

11 to 17, identify and research global issues, design research

projects around those issues, and report their results to U.N.

leaders and other scientists around the world. “ecotek is

enhancing science in Michigan by connecting science research

to global issues,” says Young. “Our students work on a wide

range of projects with member countries at the United

Nations. They also do a lot of hands-on field work with world

renowned researchers. ecotek is setting the bar for science

education in Michigan.”

In the bioscience area, one project involved understanding

how to deliver drugs to people in developing countries at a low

cost. “We’re working with our kids on nanochemistry so they

can understand how synthesis works and how you can apply it

to drugs as far as being able to break it down into small enough

particles that it could be delivered in a controlled dose - and

more important, reduce the cost of delivery.”

ecotek students have also studied the relationship of air

quality in developing countries to the incidence of lung cancer

and how to determine whether cardiovascular disease is

based on heredity or lifestyle. One team of student scientists

recently made biodiesel out of soybean oil, and researched

methods of converting algae and other cellulose-based materials

to biofuel. Young led a team to New York this spring to share

their research findings with the World Health Organization and

to learn what the WHO is doing to help address these illnesses

on a global scale.

In addition to working on bioscience projects in the lab, ecotek

student scientists are eligible to attend special life science programs

at top schools across the country. Five students will attend the

University of Michigan’s advanced chemistry program this summer;

others, like Amber Young, will participate in the university’s six-week

Mini Med School program. “I hope to work with different doctors

that can help me become a pediatric neurosurgeon,” she says.

Young believes the Ecotek program is vital to the development

of future scientists, and that it fills a void that exists in the school

system.

“If it was my child, to what level of depth would I go to insure

the quality of that experience sticks and is actually momentum for

them going into the future,” he says. “I have these kids compete

in national and international competitions outside of Michigan and

outside of the U.S. to see how they fare in an open environment.”

Is Young’s Ecotek program a success? I don’t measure success

in terms of whether or not we receive accolades from the school

system or from the state of Michigan, for that matter. I measure

success by the actual students and what they do.”

Ecotek Shows Studentsthe “World” of Science

EDUCATION

“Our students work on a wide range of projects with member countries at the United Nations. They also do a lot of hands-on field work with world renowned researchers.”

keitH young (front), founder of ecotek, is enHancing and coMpleMenting MicHigan’s science education prograMs by connecting science researcH to global issues.


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“In the standards set forth by the politi-

cians, the emphasis has been turning our

kids into walking encyclopedias, so there-

fore science is something that you memorize

as a bunch of facts and not something

that you do,” he says. “We need to get from

science as a noun to science as a verb, and

I think our research project does that.”

BIOSCIENCE, UP CLOSE AND PERSONAL Hundreds of students have received up close

and personal encounters with the bioscience

industry by attending the high school career

was that that was one of the most valuable

things that they did,” says Blume. “It taught

them how to gather data...and to be able to

write and defend their work. It has value

even outside of the sciences.”

Blume believes that the biosciences have

a particularly bright future because they

impact people’s lives. “Maybe there’s going

to be a bio-engineered organism that’s going

to scrub CO2 out of the atmosphere or...that

can consume toxic spills,” he says. But Blume

also believes strongly that science education

must be radically re-thought if kids are to be

successfully “engaged.”

days and college programs that run as

part of MichBio’s annual Expo. At the 2009

Expo at Western Michigan University in

Kalamazoo, students toured the University’s

biological imaging center and molecular

modeling lab. They also learned about

projects involving biomechanical research

and neurobiology.

“This is our future bioscience work-

force,” Rapundalo says. “It’s not enough to

focus on the current one. We have to be

prepared to ensure that there is a steady

pipeline of talent…that means staying

abreast of the latest technologies, techniques

and instrumentation that can be applied

in biotech research of the future. We try to

expose these kids and make them aware

that the biosciences are much more than

the traditional career paths of medicine and

nursing. You can customize your career to

suit your own interests, skills and passion.”

“This is our future bioscience workforce... It’s not enough to focus on the current one. We have to be prepared to ensure that there is a steady pipeline of talent…”

a Van andel institute study indicates tHat 80% of eleMentary students are excited by science. tHe key is to Make it stick.

EDUCATION


This place thinks like you think. Kettering UniversityPartner with Kettering and use the nation’s most advanced cooperative education students to build a highly productive professional workforce. Innovation and entrepreneurship are infused throughout all of Kettering’s engineering, science, math, and business programs, and Kettering is known for educating leaders for a global society.

Any university will take you places. Kettering will take you farther.

think.kettering.edu 800-955-4464 ext. 7865

Derek Hazard ‘11Applied Physics and Applied MathCo-op: Umicore AutoCat


science, disease models, drug discovery, tis-

sue engineering, bioreactors and nanotech-

nology. Experts will present progress reports

on treatment for cancer, diabetes, spinal

Michigan to Host World Stem Cell Summit

Michigan—through its voters and its research—showed the world its commitment to stem cell research.

Now the global community of stem cell researchers will make Michigan its world stage.

Michigan this fall hosts the prestigious

World Stem Cell Summit, produced by the

Genetics Policy Institute (GPI). The sixth

annual summit (co-hosted by the University

of Michigan, Michigan State University, Wayne

State University, and the Michigan Economic

Development Corporation) will be held Octo-

ber 4-6 at the Renaissance Center in Detroit.

“The Genetics Policy Institute selected

Michigan because the state is the anchor of

stem cell research in the Great Lakes region,

home of world-class research institutions

and dedicated to advancing the regenerative

medicine industry,” Bernard Siegel, executive

director of GPI, explained. “In addition, the

citizens of Michigan voted to protect stem

cell research in the state’s constitution. That

sent a message that Michigan is committed

to advancing scientific research for cures.”

More than 1,200 participants from

40 states and 30 countries will attend the

summit. It will cover all areas of stem cell

cord injury, multiple sclerosis, Parkinson’s

disease, amyotrophic lateral sclerosis (ALS),

neurological disorders and cardiovascular

disease. There will also be panel discussions

on funding, commercialization, economic

development, law, ethics and regulatory

agency perspectives.

“Hosting the summit is an amazing

opportunity for Michigan,” said Sheri Mark,

president of the Board of Directors of Michi-

gan Citizens for Stem Cell Research and Cure.

“This shows the world that Michigan is a very

stem-cell-research-friendly state. We have

world-class research universities here, and a

lot of new businesses in the field of life sci-

ences are interested in locating to Michigan.”

Michigan State Senator Gretchen Whitmer

believes that the World Summit will bring

global attention to Michigan’s role in stem

cell research. “This event will showcase the

research going on in our state and demon-

strates that Michigan is going to be in the

tHe annual World steM cell report assists leaders and decision Makers to stay abreast of tHe latest deVelopMents relating to steM cells. doWnload it at WWW.WorldsteMcellsuMMit.coM.

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race for cures,” she remarked. “It’s exciting

to have the world’s attention on an issue that

means so much to so many people.”

Each of the three universities co-hosting

the summit – Michigan State University, the

University of Michigan, and Wayne State

University – will have a summit chair to rep-

resent its institution. “Being a co-host will

be an outstanding opportunity to highlight

not only stem cell research currently under-

way at Michigan State University, but also

the major research contributions from the

University of Michigan and Wayne State,”

J. Ian Gray, vice president of research and

graduate studies and Michigan State Uni-

versity, said. “Stem cell research offers great

hopes and expectations for understanding

the mechanisms of deadly diseases and

possible cures. With the talented researchers

at Michigan universities, Michigan will play

a major role in effecting change in how we

treat and, hopefully, cure such diseases.”

Similarly Steve Forrest, vice president of

research at the University of Michigan, sees

“a tremendous opportunity for Michigan

researchers to share ideas and novel science

that will impact stem cell research in the

decade ahead.”

Stephen Rapundalo, Ph.D., president

and CEO of MichBio, believes that this is a

pivotal time for regenerative medicine with

a great potential for new discoveries to be

commercialized. “The economic impact of

this Summit for Michigan is huge, and is

likely to afford an opportunity for startup

ventures in the stem cell field to launch or

expand in our state,” he said.

Hilary Ratner, vice president for research

at Wayne State University, concurred. “Stem

cell research holds tremendous potential,

and the University Research Corridor (URC)

and Michigan are well positioned to be a

major hub for advancing research in this

area,” she said. “Our Stem Cell Commer-

cialization Center, located at TechTown, our

research and technology park, will provide

significant resources and opportunities to

accelerate the discovery of stem cell-based

therapies, while at the same time stimulat-

ing Michigan’s economy in new directions.”

detroit takes tHe World stage oct. 4-6 WHen tHe city plays Host to tHe World steM cell suMMit.

MSU Business-CONNECT links your business to world-class knowledge experts.

Charles Hasemann, Executive Director ∙ [email protected]

Connect your business to MSU today!

MSU Business-CONNECT can help you leverage Michigan State University’s wealth of resources, efficiently and effortlessly, helping you tap into areas of the university you might not have known existed. Whether it’s biofuels and biomaterials, sustainability or supply chain, Business-CONNECT can be your single point of contact to put the right resources and people together to make it happen.

—Work with our faculty researchers to develop new ideas, help reduce your ideas to practice, or refine and test your products.

—Partner with us to bring MSU faculty innovations to market.

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Mi BiO-indUStRy QUICK FACTS# Bio Companies & Organizations:

>525# Bioscience Jobs:

40,086# Spin-Off Jobs:

58,721Average Bioscience Salary:

$73,390Total Payroll:

$2.5 billioneconomic Impact:

$9.5 billionTotal Bioscience Start-Ups Since 2002:

122

ACADEMIC BiO-ReSeaRch UNIVERSITY RESEARCH CORRIDORTotal R&D:

$1.4 billion (#11 best in the nation)

Biosciences R&D:

$916 million (#10 best in the nation)

# of Biosciences Degrees:

4,721 (#8 best in the nation)

# of Bioscience-Related Patents:

2,225(2002-07)

BiO-indUStRy inveStMent, COMMERCIALIZATION RESOURCES & INCENTIVESLife Sciences Corridor Fund – 21st Century Jobs fund:

$323 million(1999-2009)

vC Investments:

$268.7 million(2002-07)

Total $ Raised:

$68.8 million (#11 best in the nation 2009)

DATA



21st Century Investment Fund:

$109 million fund-to-funds$46 million to biosciences venture Michigan Fund:

$95 million fund-to-funds (2007-09)

MI Pre-Seed Capital Fund

MI Microloan Fund

Angel Investor Tax Credit

R&D Tax Credit

R&D and Bio-Manufacturing Tax Exemption

NOL Carryover

SBIR Match

n Pfizer

n Sequenom

n Perrigo

n Genetics Squared

n Stryker

n Rockwell Medical

n Oxford Biomedical

n JHP Pharmaceuticals

n Phadia

n Pioneer Surgical

n Asterand

n Housey Pharmaceuticals

n Neogen

n QuatRx Pharmaceuticals

n Accuri Cytometers

n Lumigen

n Ferndale Labs

n BD Diagnostics

n Assay Designs

n Ash Stevens

n esperion Therapeutics

n Kalexsyn

n Dow Chemical

n MPI Research

n NanoBio

n Somanetics

n vestaron

n Kellogg

n Terumo CvS

n Atek Medical

A SAMPLE OF BIOSCIENCE COMPANIES IN MICHIGAN


Distribution of Michigan bio-companies by sectorPharma & Therapeutics 23%

Medical Devices/Equipment 35%

Research & Development 20%

Testing/Medical Labs 5%

Information Technology 7%

AgBio & Industrial Biotech 10%

Pharma & Therapeutics

Medical Devices/equipment

Research & Development

Testing/Medical Labs

AgBio & Industrial Biotech

Information Technology

Drive in the Fast Lane...

GLEQ moves Michigan’s life science and medical device companies into the fast lane with entrepreneurial education, one-to-one coaching, connections to resources, exposure to investors, and a statewide business plan competition. Accelerate a new idea or an emerging company with GLEQ.

Prizes to be awarded June 10, 2010.

Learn more and register for the competition at: www.GLEQ.org

Great Lakes Entrepreneur’s Quest

GLE Inspiring Success


We prepare the broad-based scientists your organization needs

• MedicalandBioinformaticsM.S.

• CellandMolecularBiologyM.S.

• BiostatisticsM.S.

TM

COUNTONGRANDVALLEYSTATEUNIVERSITY’SPROFESSIONALSCIENCEMASTER’SPROGRAMSTOHELPMEETYOURORGANIZATION’SOBJECTIVES.When you hire a Grand Valley PSM student for an internship or permanent position, you get an employee with a versatile skill set that includes the scientific training necessary to advance and excel in science and the highly developed business skills your organization needs. For more information about our students and programs and how you can put them to work for you, contact Dr. David Elrod, PSM program coordinator.(616)331-8643|[email protected]|www.gvsu.edu/psm


ENTREPRENEURSHIP THRIvESin Michigan

ENTREPRENEURS

An entrepreneurial culture has taken hold in Michigan, spurred by innovative biosciences professionals and supported by a robust network of business development organizations along with state programs and resources. Following is a snapshot of some entrepreneurs

and their companies that illustrates a diversity of products and technologies that are being commercialized

within the state.

By David L. Shenkenberg

ALGAL SCIENTIFIC CORPORATION The idea for Algal Scientific was born dur-

ing a father-son research outing on Lake Erie

in 2008. Geoff Horst was sampling algae for

his Michigan State University doctoral dis-

sertation with his father, Paul Horst, currently

an Entrepreneur-In-Residence at Rocket

Ventures in Toledo, Ohio.

With a power plant on the lake’s western

shore as inspiration, the two speculated

on the ability of algae, some of the fastest

growing life forms on earth, to clean up

pollutants from industrial facilities. Those

discussions led to the formation of a team

with graduate students at the University

of Michigan, which competed in and won

the $65,000 Clean Energy Prize from the

University of Michigan and DTE Energy as

well as a $5000 award from the university’s

Frederick A. and Barbara M. Erb Institute.

The winning concept was to remove

polluting nutrients such as nitrogen and

phosphorus from wastewater that contribute

to $4.3B in costs to society in the USA. The

company’s process uses proprietary algal

strains and technology to scrub the waste-

water and produce clean water and algal

biomass that can be turned into biofuels,

fertilizer, and other valuable by-products.

The company’s process uses proprietary algal strains and technology to scrub the wastewater and produce clean water and algal biomass.


ENTREPRENEURSBioArbor Gives Entrepreneurs a Place to Network and Learn When Julia Owens, Ph.D., moved from San francisco to work as the

senior director of business development for QuatRx Pharmaceuticals in Ann

Arbor, she wanted to build a local network of bioscience colleagues. Rather

than searching out the occasional meeting or event, the energetic Owens

gathered up a “think tank” of local professionals to plan monthly meetings,

and BioArbor was born.

“Our goal at BioArbor events is to bring the local bioscience community

together on a regular basis, so that we can share ideas, build relationships and

work together to foster new life sciences companies in the area,” said Owens.

Since its first official meeting in July 2007, the group has attracted a

loyal following of bio-entrepreneurs as well as students and other new-com-

ers, with attendance averaging 70–80 people a month. More than 600 people

have attended events and are now on the group’s mailing list, and the group

even has its own website (www.bioarbor.com).

“We cover technology commercialization, financing strategies, team build-

ing, business development, regulatory affairs, marketing and more, all with a

focus on the life sciences,” says Owens. “The first hour of each event is all-out

networking followed by a program and Q&A, which can be pretty lively.”

Speakers are often brought in from outside the local area and share

experiences on topics that are applicable to those in drug discovery &

development, medical devices, diagnostics and tools. A popular recurring

event, “The Good, the Bad and the Ugly,” has three or four experienced

entrepreneurs sharing their successes and mistakes that others can learn

from. BioArbor events are open to the public and are especially suited for

those interested in starting or growing bioscience businesses.

Thanks to

sponsorships by

local businesses,

such as law firms

and insurance

companies, and

support from

MichBio and

Ann Arbor

SPARK, the

meetings are

free, which

is appreciated

by entrepre-

neurs.

Most of their business will be driven by

EPA enforcement of the Clean Water Act.

“The strict regulations that started on the East

Coast are expanding across the country,” says

Geoff.

The company incorporated in May 2009 and

conducts research at the Michigan Life Science

and Innovation Center in Plymouth, MI. It

received an investment from the Michigan

Pre-Seed Capital Fund and others, and is

continuing to raise funds for future demon-

stration sites. It has six part-time employees

in addition to Geoff, who serves as Chief

Science Officer, and Paul as interim CEO.

(www.algalscientific.com)

EXT LIFE SCIENCES, INC.™

A new product from EXT Life Sciences, Inc.

of Detroit and Southfield, Mich., may bannish

gray hair and remove unsightly wrinkles. Sound

too good to be true? Time will tell. The company

has developed a breakthrough cellular targeted

antioxidant platform which can, for the first

time, deliver needed protection to a specific

compartment of human cells in order to control

or eliminate oxidant damage.

“We cover technology commercialization, financing strategies, team building, business development, regulatory affairs, marketing and more, all with a focus on the life sciences,” says Owens.

algal scientific’s proprietary algal strains not only scrub WasteWater, but tHe resulting algal bioMass can be turned into biofuels, fertilizer and otHer Valu-able by-products.

A new product from eXT Life Sciences, Inc. of Detroit and Southfield, Mich., may bannish gray hair and remove unsightly wrinkles.

Julia oWens of quatrx pHarMaceuticals Wanted a Way to connect WitH local bio-entrepreneurs, so sHe forMed bioarbor in 2007 and continues to lead tHe successful group.


Resourceful Direction forDrug DevelopmentMPI Research understands the complexities often associated with drugdevelopment decisions, and partners with Sponsors in finding innovativesolutions to their development challenges. The comprehensive servicesoffered by MPI Research include:

MPI Research is a global Contract Research Organization (CRO) that performspreclinical and select clinical studies for biotechnology, pharmaceutical, andmedical device companies. The company partners with its Sponsors in movingtheir test candidates along the regulatory pathway, in an effort to bring better,safer medications and medical products to the world.

Corporate Headquarters54943 North Main StreetMattawan, MI 49071-9399 USA+1.269.668.3336www.mpiresearch.com

Drug Safety Evaluation• General Toxicology • Developmental and

Reproductive Toxicology • Infusion Toxicology • Safety Pharmacology• Neurobehavioral Sciences,

including Abuse Liability

Resource Services• Clinical Pathology • Histopathology • Regulatory Submissions

Publishing (eCTD) • Consulting Services

(IND preparation and filing)

Discovery Services • Experimental Therapeutics• Experimental Surgical Models • Molecular Imaging • Immunology • ADME/Pharmacokinetics

Bioanalytical/Analytical Sciences• Method Development• Validation to Support Small and

Large Molecule Therapeutics

Medical Device Evaluation• Regulatory Guidelines (ISO 10993)• Interventional Device Evaluation• Surgical Device Evaluation• Other Models

The product is a proprietary enzyme

called CATSKL™, which is based on the

naturally occurring antioxidant, catalase.

CATSKL™ originated from the collaborative

research of scientists at the Wayne State

University School of Medicine in Detroit,

and the University of Western Ontario in

London.

Because antioxidants have been shown

to be integral to the fight against various

diseases inside the body, the product also

could have pharmaceutical applications,

although the company plans to target cos-

meceutical applications first, before moving

onto pharmaceutical testing.

“We’re at a point where we have an effec-

tive molecule that tests have shown can act

without toxicity,” said John Tesija, JD, vice

president and head of operations at EXT.

The company plans to partner with other

firms to develop and market its products in

both the cosmeceutical and pharmaceutical

fields. (www.extlifesciences.com)

REALBIO™ TECHNOLOGY RealBio Technology, Inc. was founded

when Paul Neeb, working as an Executive

in Residence with the SWMF Life Science

Fund, sorted through various early stage

projects and found one that inspired him.

The project that Neeb, an M.B.A. from

Northwestern University’s Kellogg School

of Management, found was a 3D cham-

ber for growing stem cells developed by

Aastrom Biosciences in Ann Arbor under a

grant from the Defense Advanced Research

Projects Agency. The chamber was originally

designed to sustain human bone marrow.

“What makes us unique is that the

technology was formed in Michigan, manu-

factured in Michigan and commercialized

in Michigan,” Neeb, now RealBio’s President

and CEO, said.

Typically cells used in biomedical

research are grown on a flat Petri dish rather

than in a chamber that allows the cells to

grow in 3D as they would in the human body.

The 3D chamber sold by RealBio Technology

is ‘bio-realistic’, that is, closely resembles the

in-vivo environment for cell growth.

Funded in part through the SWMF

Life Science Fund, RealBio Technology has

realbio tecHnology’s culture systeM facilitates tHe groWtH of in Vitro cultures in a Manner Mirroring natural in ViVo cell and tissue deVelopMent beyond tHe liMitations of current 2d and 3d tecHnologies.

“What makes us unique is that the technology was formed in Michigan, manufactured in Michigan and commercialized in Michigan.”


developed the RealBio Culture System; a

disposable cell culture technology offering

significant advancements beyond cur-

rent 2D and 3D technologies. It is the first

commercially available culture system that

enables cells to migrate out of the culture,

which allows the culture to be maintained

for a long period of time.

(www.realbiotechnology.com)

WELLNESS INDICATORS INC. Although antioxidants have been

shown to fight diseases in humans, there

is currently no convenient way for people

to determine whether they are receiving a

beneficial level of antioxidants from dietary

supplements and foods.

Wellness Indicators Inc., of Rochester

Hills, Mich., is developing testing supplies

that can measure biomarkers for oxidative

damage, antioxidant capacity and inflam-

mation (another major risk factor for

multiple diseases) in human urine. Initially

the tests will be administered in clinical

settings such as a doctor’s office, according

to company CEO, Denis Callewaert, Ph.D.

Before founding Wellness Indicators,

Callewaert founded several other companies,

including Oxford Biomedical Research, where

he is currently CEO. He built his businesses

gradually with National Institutes of Health

Small Business Innovation Research grants

while a professor at Oakland University.

For Wellness Indicators, Callewaert

received an initial angel investment that

included valuable resources for building the

business plan and investor materials. The

company is in the process of completing a

$500,000 private placement and is seeking

venture capital. Eventually, he hopes to

step down as CEO of Wellness Indicators

and become CTO or CSO.

(www.wellnessindicators.com)

AZENIC DENTAL, INC.™

Azenic Dental, Inc. is a device company

focusing on meeting dental market needs

in the area of disposable instruments.

Co-founded in 2005 by the Apjohn Group,

a Kalamazoo-based life-sciences business

consulting company, Azenic very quickly

met significant milestones in staffing, fund-

raising, product design and development.

In February 2008, Azenic received U.S.

Food and Drug Administration clear-

ance to market a new, patented disposable

high-speed dental drill, the Azenic DHP™

(Disposable High-Performance Handpiece),

an important development in a progressive

profession moving toward individualized

care where patient-to-patient cross contami-

nation is a concern.

C. Mac Waldorf, M.B.A., a founding

principal of the Apjohn Group and CEO of

Azenic cited the high quality of human capi-

tal and the lower cost of living as reasons for

doing business in Michigan, as well as the

access to funding sources through state and

local investors. “The quality of local product

manufacturers and professional service

providers is a tremendous help to start-up

companies such as Azenic,” he said.

(www.azenic.com)

CYTOPHERX About 84,000 people each year will die

from acute kidney failure in the U.S and one

Ann Arbor company predicts that it “could

save up to 70 percent of them,” according

to its CFO, Mark R. Morsfield, M.B.A. The

company, CytoPherx, was founded in 2007

and aims to significantly reduce mortality

from acute kidney failure with a medical

device that significantly reduces the body’s

inflammatory response.

The device attaches to a kidney dialysis

machine, collects and deactivates activated

white blood cells that are causing a danger-

ous systemic inflammatory response. It

originated from the research of Dr. H. David

Humes at the University of Michigan Medi-

cal School.

The company recently changed its name

from Nephrion to CytoPherx to indicate that

its device may have applications beyond

kidney failure such as treating inflammation

during coronary bypass surgery and treat-

ing severe sepsis and other inflammation

mediated diseases. In all cases, the device

will help patients with life-threatening

conditions. “It’s been 30 years since there

have been meaningful therapeutic advances

to these disease states,” said Morsfield.

CytoPherx won a $2 million 21st Centu-

ry Jobs Fund grant in 2008 from the State of

Michigan and has received some investment

from the Bioscience Research and Com-

mercialization Center at Western Michigan

University, as well as private equity invest-

ment and venture capital including North

Coast Technology Investors of Ann Arbor

and Apjohn Ventures from Kalamazoo. The

company’s device is in the pilot phase of

clinical trials and subsequently will move

to the pivotal phase, the final phase before

it can be cleared by the FDA and sold in the

U.S. (www.cytopherx.com/)

azenic dental receiVed fda approVal to Market its disposable HigH-speed drill, ansWering tHe call for dental instruMents tHat protect patients froM cross contaMination.

Wellness Indicators Inc., is developing testing supplies that can measure biomarkers for oxidative damage, antioxi-dant capacity and inflammation in human urine.

CytoPherx aims to significantly reduce mortality from acute kidney failure with a medical device that significantly reduces the body’s inflamma-tory response.

ENTREPRENEURS


During its annual Expo & Conference, MichBio presents one

individual with the Innovator of the Year Award, recogniz-

ing his or her significant contribution to the advancement of

knowledge and understanding of biological processes through

a novel and innovative technology, process, or product. The

2009 recipient, John Nanos, fits that profile well.

Raised in Dearborn, Mich., Nanos earned his BA in chemis-

try from Kalamazoo College and went on to earn a Ph.D. at the

University of Michigan within their MacroMolecular Science and

engineering program. While working for a mid-Michigan medi-

cal start-up company, Nanos taught organic chemistry at the

UofM before moving back to Ann Arbor in 2003. In 2005, Nanos’

entrepreneurial bug pushed him to form his own company and

Nanosystems was born.

Nanosystems’ core business is polyurethane foams and

cellular plastics for medical and specialized industrial ap-

plications, but it is gradually replacing them with bio-based

products, which now account for about 15 percent of the

company’s approximately $3.5 million gross revenue. Nanos

developed a novel bio-based technology and polymer as soil

additives and replacements for petroleum-based plastics,

foams and other materials.

Polyurethanes have been widely used since the 1950’s and

today they pervade every aspect of our society from deck

coatings, to padding for beds, furniture and cars, to protection

of shipped goods, to implantable devices. Until early 2000, all

polyurethane and plastic products ultimately originated from

crude petroleum oil. “We’re slaves to petroleum,” Nanos said,

“governments covet this liquid gold

and we’ve become addicted to it.”

The chief barrier to replacing

petroleum with bio-based products

is cost and the petroleum paradigm.

“Renewable technologies are mature

enough to match the performance

requirements of many existing oil-based

thermosets and thermoplastics,” Nanos

said, “but it takes time to build the

bio-based infrastructure to compete

economically and to break down oil

barriers.”

Nanosystems’ biobased chemistries

are safe for the environment because they are created from

renewable resources. The company is replacing polyurethane

in products as diverse as surfboards, agricultural binders used

to hold roots of plants together, packaging materials used in

shipping, and rigid foam used as structural support for electri-

cal transmission poles. “I got lucky in chosing niches that were

receptive to bio-

technologies. I found

captive audiences

that craved greener

materials.”

In 2008, Nanos

formed a joint ven-

ture, Inos Technolo-

gies, with a Japanese

based global leader

in polyurethane

chemistries called

Inoac. Inoac is a

privately held com-

pany that shares Nanos’

passion to respect the

power of petroleum but to search for and nurture bio-technolo-

gies that leave a softer footprint for future generations. With labs

in Ann Arbor, Inos also will be the North American R&D center for

Inoac products.

“Along with the strong support of entities such as MichBio,

SPARK, and the U of M, we’re trying to build Michigan into a

biotech leader.”

Nanosystems’ biobased chemistries are safe for the environment because they are created from renewable resources.

Nanos developed a novel bio-based technology and polymer as soil additives and replace-ments for petroleum-based plastics, foams and other materials.

ENTREPRENEURS

tHis “groW plug” is 95% canadian peat Moss bound WitH 5% of a bio-based and biodegradable adHesiVe. groWers like tHe plug because it Holds tHe peat and tHe root systeM intact during replantings, Manipulations, and sHipping, reducing Mortality and iMproVing groWtH. JoHn nanos is on a Mission to deVelop otHer siMilar enVironMentally friendly tecHnologies.

JoHn nanos recently forMed a Joint partnersHip WitH Japanese coMpany, inos tecHnologies, WHicH sHares His passion for finding bio-based tecHnologies tHat can do tHe saMe Jobs of petroleuM-based products, but be kinder to tHe enVironMent.


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One-StOP ShOPPing Herbert describes Neogen as a one-stop shop for food

and animal safety products. “This is...not a one-product

company. It’s a solutions company,” he says. “We develop

diagnostic products to be able to identify where there are

problems relating to food and animal safety and then we

have intervention products that are able to help intervene

to help solve those problems.” The company offers over

200 diagnostic products that identify contaminants ranging

from yeast and molds to e. coli, salmonella, Listeria, and

Campylobacter.

“Our concept was the food industry couldn’t afford

the time or the dollars to pull samples and send them

out to some independent lab and get the results three to

ten days later — they needed to know on site before they

[determined] whether it could be used,” Herbert says. “We

developed tests that could be used by someone who was

not a trained technician and were simple and easy to use.”

Neogen has been a perennial bright spot in the other-

wise lackluster Michigan economy. Its total revenues have

increased from $72.4 million in 2006 to $118.7 in 2009,

and net income has grown from $7 million to $13.9 mil-

lion in the same period. Its investor presentation boasts

of year-on-year revenue increases for 71 of the past 76

quarters, and 67 consecutive quarters of profitability.

Neogen was named in 2006 to the NASDAQ Global

Select Market tier, which has the highest initial listing

standards of any exchange in the world. In 2009, it was

included in Fortune magazine’s “40 Stocks to Retire On”

and was named as one of Forbes magazine’s “200 Best

Small Companies in America.”

Reports of contaminated pet food from China shocked

readers in recent years, but the threat appears not to be

confined to animals. In April 2007, the New Straits Times Press in Malaysia ran a story asserting that some farmers in

China were injecting an industrial dye into eggs to make

the yolks look fresher and that fishermen used malachite

green, a suspected carcinogen, to improve the appear-

ance of some freshwater fish.

“Over half of the seafood that’s consumed in the

United States comes from China,” says Jim Herbert,

chairman and CEO of Lansing-based Neogen Corp. “U.S.

purchasers of seafood and Chinese officials are very

concerned that the products purchased from China are

going to be safe for the people in the U.S. to eat.”

Neogen, which develops and markets a wide range

of diagnostic tests for food borne bacteria, food allergens,

and drug residues as well as veterinary products, is

mounting a food safety initiative in China, and Herbert

sees strong demand from exporters and importers alike.

“We’ll introduce a brand new product to China in the

spring. It’ll be used to make certain that they don’t have

a residue contamination, and that same test will be used

by receivers on this end to make certain that somebody

did test it and it is, in fact, safe,” he says.

Herbert describes Neogen as a one-stop shop for food and animal safety products. “This is...not a one-product company. It’s a solutions company.”

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FOUR-POint gROwth StRategy Herbert attributes Neogen’s success to its four-point

growth strategy, which includes growing sales from existing

products, introducing new products (“We have 55 people

in our R&D organization developing new products.”);

expansion to international markets (“Over the last three

years we’ve grown our revenues from sources outside the

U.S. from 27 percent to 42 percent.”); and acquisitions

and strategic alliances (“We’ve done about 16 acquisitions

over the last nine years.”).

Neogen has changed dramatically since Herbert

started the company in 1982 with a secretary and a

couple of used desks. It now employs 550 people in

the U.S., Mexico, and Scotland. But Herbert’s guiding

philosophy has not changed: adhere to the mission of

being a dominant player in the food and animal safety

industry, hire good people, and eschew dramatic growth

spurts in favor of steady expansion.

“We had a lot of people who believed in what we

were doing, believed in the dream,” he says. “With

those smart people, you’re able to make adjustments

and fulfill that mission. It’s setting up...a pretty good

discipline from the very beginnings to where we wanted

to be and then having the stick-to-itiveness to stay the

course. That’s how we did it.”

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Michigan, like many other states, is competing for the attention of the global biosciences industry in an attempt to diversify and grow a knowledge-based economy. The state has a vibrant biosciences

industry with a long history rooted in the pharmaceutical and medical device sectors.

PUBLIC POLICY

By Tom Beaman


Michigan House and Senate Appoint Legislative Groups

to Focus on the

BIOSCIENCE INDUSTRY

According to MichBio President and CEO

Stephen Rapundalo, Michigan’s biosciences

industry accounts for about 100,000 direct

and indirect employees, $2.5 billion in pay-

roll, $500 million in tax revenues, $9.5 billion

of the state’s gross domestic product, and it is

the largest high tech sector in Michigan.

OUT OF SIGHT, OUT OF MIND Despite such a significant economic

impact, Michigan’s biosciences industry

has largely been out of sight, out of mind.

“Visibility of the state’s life sciences industry

has diminished from a few years ago when

the state had a very identifiable Life Sci-

ences Corridor Fund to directly support the

industry,” he says. “Legislators in Lansing

simply weren’t aware of the positive and

considerable contribution made by the

state’s biosciences industry once the Fund

was rolled into a broader-based technology

support program.”

When Rapundalo talks about the biosci-

ence industry with legislative leaders and

Governor Jennifer Granholm, he stresses

the need for commitment, visibility, and

consistency. “First, if you want to reap the

potential benefits, one typically starts by

laying out a defined game plan and executing

on it. Next, if you’re going to be in it, you’ve got

to make the industry’s assets, capabilities and

opportunities visible to the outside world. And

last, we must keep these programs in place

over the long term and insure that terms and

conditions, features and resources are offered

in a consistent manner. We simply must keep

tHe MicHigan House subcoMMittee on biosciences is cHaired by rep. ed cleMente, WHo says He Wants to Make MicHigan as “friendly an enVironMent as possible” for biosciences groWtH.


mechanism by which legislative initiatives

targeting the industry could be developed. He

and former Congressman and long-time State

Senator Joe Schwarz, M.D., approached Senate

Majority Leader Michael Bishop in the fall

of 2008 about forming a legislative subcom-

mittee to address economic development in

the biosciences. In April 2009 Richardville

received approval from Bishop to create a

Task Force on Biotechnology as part of the

Economic Development and Regulatory

Reform Committee, which he chairs. Soon

after that, Rep. Ed Clemente (D-Lincoln Park)

was named to chair a House Subcommittee

on Biosciences as part of his New Economy

and Quality of Life Committee. As a result,

Michigan became the only state whose bio-

science industry is officially represented in

both chambers of its legislature.

Clemente’s subcommittee has now con-

ducted hearings in Ann Arbor, Rochester Hills,

and Grand Rapids. It has received testimony

from a range of stakeholders including Oakland

County Executive L. Brooks Patterson on

the biosciences industry and its resources

visible, accessible, reliable and relevant.”

Rapundalo says states that are success-

fully growing their bioscience industries have

very close relationships with their policymak-

ers, primarily in the form of either legislative

caucuses or committees. “Nothing like that

existed here in Michigan prior to 2007. The

minimal awareness of the biosciences sector’s

impact despite its size necessitated a new

approach to enhance focus and support for its

long-term growth ,” he says.

BIOSCIENCES LEGISLATIVE CAUCUS GETS THE BALL ROLLING Rapundalo decided that one way to

accomplish MichBio’s mission of driving

bioscience growth in the state would be

to convene a group of legislators who sup-

ported the industry, and were interested to

learn more about it as well as finding ways

to strengthen it. As a result the Michigan

Biosciences Legislative Caucus was created

in late 2007 with Sen. Randy Richardville

(R-Monroe) and Rep. Rebekah Warren

(D-Ann Arbor) as co-chairs. The Caucus

functions to promote, educate, discuss, and

formulate potential policy between elected

officials, the industry and public. The group

now lists over 50 legislators as “members”.

“As we started to get the caucus together,

we realized this is just a phenomenal oppor-

tunity to develop an industry that has good

paying, knowledge-based jobs that will help

keep our young people here,” says Warren.

Richardville adds, “We met every few

months and talked about legislation, appro-

priations, what kind of money was necessary,

what kind of economic development was

going on. Some of us have independently

looked at other [bioscience] incubator

models around the world, including Israel.”

COMPLETE POLICYMAKING INFRASTRUCTURE As support and awareness of the Caucus

grew, Rapundalo and others recognized

the even more important need to have a

The Caucus functions to promote, educate, discuss, and formulate potential policy between elected officials, the industry and public.

“...this is just a phenomenal opportunity to develop an industry that has good paying, knowledge-based jobs that will help keep our young people here.”

tHe MicHigan House subcoMMittee on biosciences Has Held tHree Hearings to date receiVing testiMony froM a range of industry stakeHolders.

IA

MN

FL

VA

PA

MD

MA

CA

AZ

COKS MO

States with a Dedicated Biotechnology Caucus (11)

States with House Legislative Biotech/Bioscience Commitees (3)

States with both House and Senate Legislative Bioscience Committees and Caucus (1)

MI

IL

BIOTECHNOLOGY CAUCUSES OR COMMITTEES


behalf of the Medical Main Street initiative,

Jan Garfinkle, founder and managing director

of venture capital firm, Arboretum Ventures,

David Zimmermann, chief executive officer at

Kalesyn, a Kalamazoo start-up and contract

research firm, and Steve Treizenberg, Ph.D.,

director of the Van Andel Education Institute in

Grand Rapids. Richardville’s Senate Task Force

will begin its fact-finding in the spring of 2010.

“I’m leaving it to the experts to say

whether we need to be in medical devices, or

some other cluster, or do a research corridor,”

says Clemente. “I just want to make sure that

we make it as friendly an environment as pos-

sible [for bioscience company growth] so that

these things can happen.”

THE FIRST TASK: CONNECT THE DOTS To date, no legislation has emerged

from either the House Subcommittee or the

Senate Task Force, but when such measures

eventually see the light of day, they will come

face-to-face with the state’s fiscal challenges,

a situation faced by many other states. Tax

credits, incentives, or modifications to the

Michigan Business Tax may be enacted, but

Clemente and Warren favor, at least initially,

taking advantage of existing resources and

improving access to them.

“The question for us is not whether new

legislation is needed, but can we identify some

of the pieces that are already there? It’s con-

necting the dots,” says Warren.

Clemente sees value in maintaining a

strong Michigan Economic Development

Corporation, which has done an excellent job

of providing resources to the 15 SmartZones

and Business Accelerators, many of which

have wet-lab incubators associated with them.

“Most of this stuff doesn’t come through

the legislature, a lot of it comes through the

MEDC,” he says. “What you do is make sure

the MEDC is well funded so that they can sup-

PUBLIC POLICY

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port these kinds of industry sectors. We give

them the tools.”

Rapundalo is pleased with the response

MichBio has received in Lansing thus far.

He admits the process of re-awakening

state government’s appreciation of the bio-

science industry is in its early stages, but

he’s confident that it will receive more of the

support it needs, especially considering the

enormous potential the sector holds for the

state’s economic diversification and growth.

“The bioscience segment has an

unlimited capacity for growth,” he says. “It’s

as limitless as innovation can be. It not only

underpins our healthcare system but our

personal health and lives too. That kind of

makes it special. It’s a very meaningful indus-

try and very globally competitive. Michigan

has the opportunity to regain its leadership

position, but we’re going to have to make a

commitment to growing the sector, focus on

outcomes, and execute for success.”


Patrick Cardinali of Westland, Michigan, was diagnosed

with Parkinson’s disease in 1998. After receiving the shocking

news, Cardinali asked his doctor what he would do if he were

in Cardinali’s position. The doctor suggested that he get into

clinical trials to help find a treatment. “You never know, you

might find a drug that will help you,” he offered.

Cardinali has been involved in several trials over the years

with different medications and different outcomes. “A big

benefit was that it was free of charge while you were on the

study, so for a lot of people who didn’t have medication cover-

age, that was a tremendous savings for them,” he says.

While drug companies normally pay for the costs of clinical

trials, patients are typically responsible for the costs of “con-

comitant” medications. Many Parkinson’s studies, for example,

require that patients also be taking Sinemet, which typically

isn’t covered by the sponsor, according to Dolly Niles, president

of Quest Research Institute in Bingham Farms, Mich. Niles says

such out-of-pocket costs can range from $5 – $8 per week for a

rheumatoid arthritis prescription to much more for device stud-

ies. “Insurance would pay for that, but how many people are

insured today?” she asks. “And everyone still pays the deductible.”

The issue of un-reimbursed costs for participants of clinical

trials has caught the attention of Michigan State Representa-

tive Gail Haines (R-Waterford). Haines is currently drafting

a bill that would allow any Michigan resident who participates

in a clinical trial to claim a credit on his or her Michigan

tax return for costs (including medicines, devices, fuel, and

lodging) related to their trial that are not reimbursed by the

sponsor or insurance.

Haines’s bill has not been

formally introduced, but she

believes it would have multiple

benefits. In addition to supporting

the development of Michigan’s

bioscience sector, Haines says her

goal is to encourage the use of

clinical trials to develop treat-

ments and cures. “It shouldn’t cost people to advance medical

research,” she says.

“If at least a portion of the cost could be offset, I truly

believe it would enable more individuals and institutions to

have interest in participating in clinical trials,” says William

Baer, M.D., Pharm. D., executive director and chief medical

officer of Clinxus, a community-based research alliance in

Grand Rapids.

“We always want to see legislation that encourages

patients…to participate in trials,” says Niles. “The number

one roadblock to delaying drug approval is the clinical trial

process. If you can shorten that process by encouraging

recruitment…it gives me more leverage to say, “Bring your

study to Michigan.”

37

a tax credit Would encourage indiViduals to participate in clinical trials and enable coMpanies like MicHigan’s quest researcH institute to bring More trials into tHe state.


clinical trials tax credit could Benefit Michigan labsPUBLIC POLICY

Haines is currently drafting a bill that would allow any Michigan resident who participates in a clinical trial to claim a credit on his or her Michigan tax return for costs (including medicines, devices, fuel, and lodging) related to their trial that are not reimbursed by the sponsor or insurance.

“The number one roadblock to delaying drug approval is the clinical trial process. If you can shorten that process by encourag-ing recruitment…it gives me more leverage to say, “Bring your study to Michigan.”

representatiVe gail Haines

Southwest Michigan First

MedicalMain Street

Ann ArborSPARK

TechTown

The Right Place

economic development catalyst for Michigan’s

Kalamazoo region.

Indeed, the area is home to a host of heavy

hitters like Stryker Corporation, Pfizer Animal

Health, Perrigo, MPI Research and Borgess

Medical Center among others, plus numerous

Their names are crafted to capture the imagination with words like First, Right Place, Main Street, SPARK and TechTown. Michigan’s

five leading regional economic development and business accelerator organizations each promote their

parcel of the state’s geography with gusto.

up and comers such as Kalexsyn, Monteris,

Metabolic Solutions Development and Vestaron.

“We operate much more like a life science

consulting firm,” says Kitchens, citing the

availability of Southwest Michigan First’s af-

filiated angel and venture funds, and its large,

modern incubator and wet lab facility.

He also highlights the area’s above average

bioscience workforce, a draw that is vital to

bioscience companies; its lower cost of living

(especially compared to the coastal U.S.);

Western Michigan University’s prolific life

science labs and programs; land to spare and

its strategic location between Detroit and

Chicago.

They know they’ve got what it takes to

attract bioscience companies seeking to set

up operations or relocate: talent, financial

incentives, connections, funding sources and

space. Yet each has created its own twist on

the story and niche to promote.

KALAMAZOO REGION MAKES THE “FIRST” IMPRESSION “Southwest Michigan First is one of eight

places in the world where you can take a drug

from discovery to your pharmacist all within

the same geographic area,” touts Ron Kitchens,

CEO of Southwest Michigan First, the

“We operate much more like a life science consulting firm,” says Kitchens, citing the avail-ability of Southwest Michigan first’s affiliated angel and venture funds.

eCONOMIC DeveLOPMeNT


The Five Fingers of

Michigan’s “Upper Hand” Advantage

38


grand rapids Has Made a Huge inVestMent in building and branding its Medical Mile, an area of bustling bioscience actiVity.

INFRASTRUCTURE...AND THEN SOME...THE APPEAL OF GRAND RAPIDS REGION Fifty miles to the north along the West

Michigan corridor is Grand Rapids, another

hub where more than $1 billion has been

poured into life science development in the

past 14 years.

“We have built an infrastructure around

biosciences that is very robust,” says Birgit

Klohs, CEO of The Right Place, the area’s

economic development driver.

Consider the so-called Medical Mile, a

burgeoning stretch of real estate that started

with the 1996 founding of the Van Andel

Institute, now an internationally recognized

center for molecular cancer research. The

microcosm of research and patient care now

includes Spectrum Health’s Butterworth

Hospital, Grand Valley State University’s

Cook-DeVos Center for Health Sciences,

Michigan State University’s Secchia Center

Medical School, and Grand Rapids Commu-

nity College’s Calkins Science Center, among

other facilities, with even more under

construction or planned.

These community assets helped lure

Sequenom, a provider of genetic analysis so-

lutions, to acquire the Grand Rapids-based

...Grand Rapids, another hub where more than $1 billion has been poured into life science development in the past 14 years.

The key to successful distribution, says David Myers, sales and marketing vice

president of sales and marketing vP for Tiffin, Ohio-based Seneca Medical, is “a local

relationship...with high levels of service.”

For the provider of medical surgical supplies and equipment, it’s all about out-

servicing competitors, and that means personal relationships, “not shipping from

five states away.”

The growing company already had distribution centers servicing hospitals, surgery

centers, physicians’ offices, and long-term care facilities in Tennessee, Indiana,

Kentucky, Ohio and West virginia. So when it sought to improve and expand its service

base for current customers in Michigan, Northern Indiana and Illinois, Kalamazoo

was a natural choice. In addition, Kalamazoo-based Bronson Healthcare Group is a

major new customer of Seneca Medical, making the area even more attractive for

a distribution center.

Myers points out that the guidance of economic developer, Southwest Michigan

First, was invaluable in the process.“They really helped us understand the business

advantages of moving into that part of the state: economic viability, great workforce,

creative business development areas, distribution range,” said Myers. “When you drive

around Kalamazoo, you see the investment; you can’t help but feel excited.”

Seneca’s Kalamazoo distribution center in the Midlink Business Park in Kalamazoo

is a former GM body-stamping plant that has been designated a non-taxable Renais-

sance Zone. Seneca’s new facility will be located on 10.6 acres in the park and will

have 80,000 square feet of space, with the expansion capacity of up to 240,000

square feet. The center started with 25 employees and should have more than 50

as business grows.

“This really is the way it’s supposed to work,” said Ron Kitchens, CeO of Southwest

Michigan First. “We encourage our local community partners to share with us their

needs in return for our commitment to work with them on strategically addressing

those needs. Bronson Healthcare Group listened, brought us their requirement for a

high quality supplier in the region and worked closely with Southwest Michigan First

to identify Seneca Medical. This is a win-win for everyone.”

Kalamazoo Makes Sense for Seneca Medical


“When you drive around Kalamazoo, you see the investment; you can’t help but feel excited.”

WitH tHe Help of soutHWest MicHigan first, oHio-based seneca Medical is locating a neW distribution center in kalaMazoo’s Midlink business park to iMproVe and expand its serVice base in MicHigan, nortHern indiana and illinois.

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Center for Molecular Medicine in 2008 and

establish a presence in the area along with

a promise of employment growth over time.

A competitive package of incentives,

introductions to researchers and partners,

incubator space and financing sources is key

to recruiting companies. They “are making a

decision that they can only make once,” says

Klohs. “We are trying to position our commu-

nity as the ‘Right’ community for a company.”

OAKLAND COUNTY’S ADDRESS IS “MAIN STREET” Every town has a nucleus called “Main

Street,” but Oakland County has taken the

concept to a new level. The affluent Southeast

Michigan county has come up with Medical

Main Street, a unique alliance of world-class

hospitals, universities, medical device and

pharmaceutical companies that are leverag-

ing their resources to establish the area as a

center of innovation and influence.

Oakland County is already home to numer-

ous bioscience companies including big names

like Somanetics, Lumigen, Oxford Biomedical

Research and Rockwell Medical Technologies.

And they’ve got the statistics (7th wealthiest

U.S. county, twice the Ph.D.’s, Masters’ Degrees

and research professionals than the national

Medical staff reVieW a sonograM at crittenton Hospital, a MeMber of oakland county’s Medical Main street alliance of Hospitals, uniVersities, deVice and pHarMa coMpanies aiMed at branding tHe area as a center of excellence.

average...), the story and the practiced technique

to build their life science base even further.

According to Irene Spanos, senior business

development representative for Oakland County

Planning & Economic Development, Medical

Main Street’s board is made up of CEOs from all

of the region’s major hospitals along with some

of the top bio companies. When a prospective

client company evaluates Medical Main Street,

“that always opens their eyes.”

Spanos works with life sciences companies

that have space requirements of all shapes and

sizes. “Often times it’s office space with a little

bit of warehouse,” she says. “Some users look for

wet laboratory space. Some partner with a re-

search university and use their equipment and

have the office space in their building. Some will

have the R & D and production done internally.

Sometimes it’s an existing company that has

laboratory equipment.”

Molecular Innovations, a provider of re-

agents to scientific researchers, was a small

warehouse operation that began in President

Duane Day’s garage. Spanos explains: “When

they were looking to expand, we helped them

identify the site (a 12,600 square foot build-

ing in Novi) and arrange financing for the

building. Several people there were familiar

with Medical Main Street and wanted to be

part of that initiative.”

Michigan is not always at the top of

the list for some companies, but pointing

out costs comparisons between Michigan

and the coasts and adding incentives, like

Oakland County’s mega tax credit, make

a big difference to the decision makers.

“We just have to increase our venture

capital,” Spanos notes. And that is moving

in the right direction (see story pg. 9)

ANN ARBOR IS ALL ABOUT THE SPARK The presence of the University of Michi-

gan, with its access to leading researchers,

state-of-the-art laboratories, world-class

hospital system, and many innovative

programs to bring technologies to market, is

a magnet-like draw to the Ann Arbor area.

According to Elizabeth Parkinson,

marketing and communications VP for Ann

Arbor SPARK, the region’s official cheer

leader, “The common theme [of companies

seeking an Ann Arbor location] is the avail-

able highly skilled workforce.” In addition,

she points out the region’s ample housing

and quality schools along with “a strong

infrastructure, a major international airport,

good IT, available power, and competitive

incentive packages.”

Ann Arbor SPARK caters to the needs

of entrepreneurs with over 200 networking

and educational events per year, an active

career services program with a database

of more than 5,000 job seekers from tech-

Michigan is not always at the top of the list for some companies, but pointing out costs comparisons...and add-ing incentives...make a big difference to the decision makers.

“The common theme...is the available highly skilled workforce.”

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From discovery to the marketplaceWestern Michigan University and Kalamazoo share and celebrate a legacy of life science education, discovery and commercialization. Explore our resources.

• A vibrAnt business technology And reseArch PArk that is home to 17 life science comPAnies—mAny lAunched in the PArk’s AwArd-winning incubAtor, the southwest michigAn innovAtion center

• A biosciences reseArch And commerciAlizAtion center thAt helPs guide globAl discovery from the reseArch lAb to the mArketPlAce

• the renowned fAculty And reseArch fAcilities of A toP-100 Public reseArch university www.wmich.edu

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CMY

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DBA-A - BioMatters Ad_printready_outlined.pdf 3/12/2009 1:52:54 PM



California | Illinois | Michigan | Texas | Washington, D.C.

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We Know Life SciencesAttorneys and Government Policy Advisors on our Life SciencesTeam provide customized, multi-disciplined and collaborativeservices and formulate legislative strategies for biotechnologyand life sciences clients. Our clients range from start-ups topublic companies to nonprofits in a variety of industry sectorsincluding pharmaceuticals, health care services, biotechnology,medical devices and equipment, and computer technology andsoftware applicable to the biotechnology and life sciencesindustry. For further information or to make an appointmentwith one of our Attorneys or Government Policy Advisors pleasecontact: Jin-Kyu Koh at (313) 568-6627 or [email protected] Theresa Carroll at (734) 214-7698 or [email protected].

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BioMatters Ad 3.2010:Biotech Life Science Ad 3/3/10 2:48 PM Page 1

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nicians to CEOs, myriad loan programs, and

two business incubators with coaching and

administrative services available.

Last October, SPARK, with a coalition

of others including Wayne County, opened

a 57,000+ square foot high-tech facility in

Plymouth, Mich., that boasts wet labs, confer-

ence and office space, a cafeteria and fitness

center along with other amenities.

Currently 15 start-up companies occupy

space in the building, anchored by Esperion

Therapeutics and founded by President and

CEO, Roger Newton, Ph.D. Previously part

of Pfizer, which sold the company in 2008 to

Newton and his investors, Esperion focuses on

the discovery and development of compounds

to treat cardiovascular and metabolic disease.

“It was the resources that kept him here,”

says Parkinson. “It was his ability to attract

and recruit high-level workers. The state was

able to offer tax incentives, [and] we were

able to acquire the facility that was owned by

Pfizer.”

TECHTOWN IS DETROIT’S ENTREPRENEURIAL HEADQUARTERS “Life science companies require many

years’ growth before they have significant

revenue,” says Randal Charlton, executive

director of Detroit’s TechTown. “I think cost

control is key.”

In fact, it’s what convinced Charlton to

move Asterand, a global supplier of human

tissue and human tissue-based research

services, to Detroit from England in 2000.

Charlton founded and is the former presi-

dent and CEO of Asterand, which anchors

the TechTown business incubator that also

houses 160 other companies in a variety of

business sectors.

TechTown makes sure its space is afford-

able, with competitive rates and the option

of short-term leases. Thanks to its proxim-

ity to universities and hospitals, bioscience

companies in the area also have direct

access to resources for partnering and col-

laboration. (For example, Asterand worked

with Wayne State University to develop and

build its tailor-made laboratories.) Wayne

State’s office of Technology Commercializa-

tion is located within TechTown, an added

benefit to the entrepreneurs that reside in the

center.

“We are trying to offer a concierge service,”

Charlton says of TechTown’s approach, which

includes entrepreneurial programs like Fast-

Trac and SmartStart, networking, mentoring

and small business loans as well as access to

investors in the Midwest.

David Shenkenberg contributed to this story.


sHrader labs, a Mass spectroMetry laboratory, is one of oVer 160 sMall businesses Housed at detroit’s tecHtoWn.

ann arbor spark, in concert WitH Wayne county and otHers, opened tHe HigH-tecH MicHigan life science innoVation center in plyMoutH, MicH., last october to attract and support entrepreneurial coMpanies in tHe region.

A competitive package of incentives, introductions to

researchers and partners, incubator space and financing sources

is key to recruiting companies. They “are making a decision that

they can only make once.”

“Life science companies require many years’ growth before they have significant revenue. I think cost control is key.”

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“This is a great time for bioscience companies in Michigan as the state works to revive its economy with more technology-based jobs. the human resources are also available as the state’s outstanding colleges and universities graduate top students in the biosciences.

Jim Herbert, CEONeogen Corporation

“… a wealth of talent with an unbeatable work ethic. Michigan is a great place to live and grow a biotechnology company.”

Bill BrinkerhoffCOO, Cerenis Therapeutics

“… easy access to world-class research and talent coupled with readilyavailable transportation makes Michigan a distinctive place to run abioscience company.”

Karen Studer-RabelerVP, Business Development, Coy Laboratory Products

“… the presence of several biotechnology incubators and state funding provide an ideal environment for starting a biotechnology business.”

Dean ShinabargerCEO, Micromyx

“… bright ideas, superb collaborators, talented and experienced employees of all types, solid infrastructure, capital -- and it is a fabulous place to live!”

Jen BairdFormer President & CEO, Accuri Cytometers

“… a wide variety of resources to support early stage development including funding, mentors, trial sites, a nurturing culture and much more.”

Stuart MainCEO, HealthCure LLC

“One advantage of a Michigan-based company is the cost of running a business. The few competitors we have simply can’t compete with us based on overhead cost. Simply put, we can do the same work for less and still have a higher profit margin. this benefits the client and eventually, the patient.”

Daniel Ross, President & CEOTransPharm Preclinical Solutions, LLC

“… the brain power and diversity of resources (You have a whole corporation essentially right here in your own backyard!)”

Loretta Cipkus Dubray President and CEO, Global Clinical Connections, LLC

“… an excellent location for medical device companies. The state has a large pool of highly trained engineers, a tradition of skilled assembly workers, strong University presence with medical, engineering and business resources to draw from and an underutilized but rich sup-plier base.”

Mark SutterCEO, Terumo Cardiovascular Systems

“… a phenomenal place to accelerate the development of your life science business because of outstanding talent, agile commercializa-tion infrastructure, and access to venture funding.”

Linda Chamberlain, Ph.D.Executive Director, Center for Entrepreneurship & InnovationGrand Valley State University

What’s So Good About Doing Bio-Business in Michigan? Let These Industry Leaders Tell You…

OPINION


My

Opi

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G U E S T O P I N I O N

academic-industry Partnerships: Reaching Out, Reaching In By Jim O’Connell and Daryl Weinert Over the past decade, there has been a trend in many U.S. industries towards less

in-house research and development. Cutting edge technologies are very unpredictable,

both scientifically and commercially. Instead of internally supporting 10 unpredictable

technologies, to maintain consistent financial performance, it makes sense for a company

to look towards mergers and acquisitions for the “next new thing.”

During this same timeframe many universities have begun to understand the value of

commercialization as an important extension of their traditional “basic science” mission.

There are now a large number of programs within Michigan universities and colleges focus-

ing on both learning about and teaching “how to translate technology to industry.”

These programs look to de-risk technologies in an effort to “tee up” licensing deals for

companies and create business opportunities for startup companies. For universities to

effectively de-risk, they have to understand the risk perspective across many industries.

The only way to accomplish this is through regular interaction and partnering with industry.

At the University of Michigan, two entities have been created to reach out and reach in.

In order to unlock the potential of academic-industry partnerships it is critical that

academic institutions develop mechanisms that will support the general ecosystem for

industrial interaction on campus. Traditionally ‘corporate relations’ on campus was a

one-dimensional effort, focused exclusively on the philanthropic relationship between

industry and the university. But here in Michigan that paradigm is rapidly evolving, and

the University of Michigan, Michigan State and Wayne State are all moving forward with

broadly reaching ‘corporate relations’ offices that can help bioscience companies find talent,

explore research partnerships, educate their professional staff, identify technologies, engage

with students, and consult with faculty. Industry now needs to develop similar mechanisms

to promote mutually beneficial connections. At the University of Michigan, this entity is

known as the Business Engagement Center (www.bec.umich.edu).

On the business creation side of the equation, the Michigan Venture Center has been

created to serve as a central connection point for venture opportunity creation resulting

from of University of Michigan intellectual property. The Venture Center takes tech-

nology and faculty with potential to form a startup company, and connects them with

both external entrepreneurs and investors. Staffed with startup and industry-experienced

business people, they form the bridge between the needs of the business world and the huge

technology potential that exists inside the university. A great example was one of the largest,

venture capital series “A” finance rounds in the Midwest; Histosonics, a startup company

based on a novel treatment for benign prostate hyperplasia, recently received $11 million.

With groups like these specifically focused on enhancing the interaction between

academia and industry, we can expect to see an acceleration of new opportunities coming

out the doors of all Michigan universities and colleges to support the bioscience industry

in the state.

Jim O’Connell is the director of the University of Michigan’s Michigan Venture Center

(innovationeconomy.umich.edu/michigan-venture-center/).

Daryl Weinert is the executive director of U-M’s Business Engagement Center

(bec.umich.edu/index/).


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MichBio is pleased to provide the 2010 Michigan Biosciences Directory and Resource Guide, the most comprehensive listing of the state’s biosciences companies and organizations.

The complete directory, which includes the information here plus profiles, and listings by sector and county is available at www.michbio.org.

Please Note: Information contained in the 2010 Michigan Biosciences Directory and Resource Guide is as current as possible. All attempts were made to validate information submitted by companies and to update existing data in MichBio’s database. If your company or organization is not listed, and you believe it should be, please visit the MichBio website at www.michbio.org and register your company. Direct questions to MichBio at [email protected] or 734.527.9150.

2010 DIRECTORY and RESOURCE GUIDE

BioMattersM A Y 2 0 1 0

MichiganBiosciences


CENTERS OF EXCELLENCEBiosciences research and Commer-cialization Center of Western Michigan

University is a commercially focused and

science driven translational research center

that dedicates its pharmaceutical expertise

and resources to the commercialization of

promising bioscience discoveries and the

growth of Michigan’s bio-science business

sector.

www.brcc.wmich.edu

(269) 544-1072

Grand river aseptic Pharmaceutical Packaging is a fully validated, FDA/cGMP

facility associated with the VAI and Grand

Valley State University (GVSU) and serves

the bio/pharmaceutical industry by offering

aseptic fill-finish, lyophilization, client-driven

custom packaging services and cold product

storage.

www.grandriverapp.com

(616) 644-0555

Michigan animal Models Consortium (MaMC) provides services associated with

the development, analysis and maintenance

of mouse models of human disease. The

consortium combines the technological,

IP expertise and facility resources at the

AAALAC-accredited Van Andel Institute

(VAI). The MAMC provides efficient and

cost-effective animal modeling services.

www.ctaalliance.org/cta-cores/michigan-

animal-model-consortium

(616) 234-5684

Michigan economic Development Corporation (MeDC) is the state’s one-

stop resource for businesses seeking to grow

in Michigan. Created through cooperation

between state and local governments, the

MEDC works with local communities and

businesses to retain and expand job op-

portunities and improve Michigan’s overall

business climate.

www.michiganadvantage.org

(888) 522-0103

Michigan Small Business & technology Development Center (SBtDC) provides

counseling, training, research and advocacy

for new ventures, existing small businesses

and innovative technology companies. Head-

quartered at Grand Valley State University,

the SBTDC supports 12 regional offices and

over 30 satellite offices in the state.

www.gvsu.edu/misbtdc

(616) 331-7480

New enterprise Forum links entrepreneurs

with management expertise, joint venture

partners, business services, capital, and other

critical resources.

www.newenterpriseforum.org

(734) 665-4433

Small Business association of Michigan

helps Michigan small businesses succeed by

promoting entrepreneurship, leveraging buy-

ing power and engaging in political advocacy.

www.sbam.org

(800) 362-5461

GENERAL RESOURCESMichBio is the statewide association committed

to building Michigan’s biosciences industry into

a growth engine for a revitalized economy. Its

members are biosciences companies, academic

and research institutions, bioscience service

providers, and related organizations. MichBio

is dedicated to fostering their collective impact

by connecting its members with the essential

resources, including goods, services, educational

and networking programs, legislative representa-

tion, and partners that facilitate success.

www.michbio.org

(734) 527-9150

BioConnections is a job bank resource for

MichBio members matching talented life

sciences pro-fessionals with fulfilling positions

in the state through an online talent search

mechanism.

www.michbio.org/BioConnections

(734) 527-9150

Great Lakes entrepreneur’s Quest (GLeQ) helps Michigan entrepreneurs build high-

growth, new economy business ideas into suc-

cessful ventures by linking them to a statewide

network of resources, expert advice, educa-

tion and capital. Twice a year, GLEQ hosts a

statewide business plan competition with cash

prizes, media exposure and business develop-

ment services.

www.gleq.org

(734) 527-9151

Abundant Resources Help Ideas Become

Life-Changing Realities


Michigan antibody technologies Center (MatC) consists of the Monoclonal

Antibody Technology Core at the VAI and

the Hybridoma Core at the University of

Michigan (U-M). The MATC has extensive

capabilities in the generation, characteriza-

tion, scale-up and purification of mAbs and

fragments.

www.vai.org/Research/Labs/AntibodyTech-

nology.aspx

(616) 234-5342

Michigan Biological Imaging Center (MBIC) provides comprehensive scientific/

technical imaging expertise including drug

safety and efficacy data to pharmaceutical

industry clients.

homepages.wmich.edu/~eversole

(269) 387-5640

Michigan Center for Biological Infor-mation (MCBI) provides advanced bio-

informatics and computational resources

for investigators and in the academic and

industrial sectors. This includes access to

bioinformatics tools, genomics and proteomics

databases, supercomputing resources, bioinfor-

matics training, and bioinformatics consulting.

www.ctaalliance.org/MCBI

(734) 615-5814

Michigan Center for Bioscience Commercialization (MCBC) is a contract

research and development organization

located at the BRCC. The MCBC provides

scientific, medical and regulatory consulta-

tion to aid in the development and commer-

cialization of pharmaceutical, diagnostic

and medical device discoveries.

www.brcc.wmich.edu

(269) 544-1072

Michigan Center for Structural Biology (MCSB) is designed to provide state-of-the-

art instrumentation and support in the area

of macro-molecular structure/function de-

termination for drug discovery. This includes

x-ray crystallography, NMR spectroscopy,

EPR spectroscopy, single molecular spectros-

copy, protein expression and production and

macromolecular structure, synthesis and

sequencing. The MCSB is partnered with and

utilizes beamline resources at the Argonne

National Labs.

mcsb.bch.msu.edu

(517) 355-0199

Michigan High-Throughput Screening Center (MHtSC) is a contract research

facility providing services in assay develop-

ment and optimization and high throughput

screening. Staffed by pharmaceutical industry

scientists with drug discovery and HTS

experience, the MHTSC offers screening of

a 100,000+ compound library for a broad

range of therapeutic targets with the client

retaining IP rights to compounds identified

in the screenings.

www.mhtsc.kvcc.edu

(269) 353-1582

Michigan Proteome Consortium (MPC)

provides proteome mapping (protein interac-

tion maps, membrane protein analysis, post-

translational modifications), high-throughput

yeast two-hybrid screening, and proteome

informatics services to both academic and

industry clients.

www.proteomeconsortium.org

(734) 763-3130

Wayne State university applied Ge-nomic technologies (MCGt) provides

oligonucleotide genechip microarrays, custom

cDNA microarrays, and other genomic tech-

nology services on a fee-basis. State-of-the-

art equipment and a full suite of molecular

genomic tools for processing and analysis

means an integrated offering for gene

expression profiling and HTS data mining.

www.bioinformatics.wayne.edu/MCGT

(313) 577-3555

Michigan-BaSed FUnding SOURCESThe 21st Century Jobs Fund represents

a bold initiative to diversify Michigan’s

economy and stimulate job creation in

emerging technology sectors. After being

introduced by the Governor in 2005, it re-

ceived broad, bi-partisan support in the state

Legislature. Using tobacco settlement dollars,

it has already invested $156 million in over

95 commercialization projects in the life

sciences, advanced manufacturing, alterna-

tive energy, and homeland security/defense

sectors through business plan competitions.

In addition, the 21st Century Jobs Investment

Fund was deployed to invest $109 million

in venture capital and private equity funds.

To date nearly $75 million has been invested

and attracted significant fund management

activity to Michigan, providing Michigan

entrepreneurs access to more diverse capital.

www.michiganadvantage.org/21

Michigan Initiative for Innovation and entrepreneurshipThe Michigan Initiative for Innovation &

Entrepreneurship (MIIE) builds on

Michigan’s universities as economic assets

by speeding the commercialization of

university research while promoting a culture

of entrepreneurial risk-taking. The initiative

partners Michigan’s philanthropic resources

with university and private business resources

to help launch new startup companies, and

strengthen ties between small business,

industry and academia.

www.pcsum.org/miie.html

(734) 647-5730

Michigan Pre-Seed Capital Fund

supports high-tech start-up companies as

they near commercial viability by providing

access to early-stage capital to accelerate

company development. These funds extend

the personal investment of entrepreneurs

during the critical stage when they are

developing their businesses to the point of

readiness for outside investment. Information

is available from local SmartZones™ or

www.AnnArborUSA.org

Venture Michigan Fund is a $95 million

venture capital investment program formed

under the Michigan Early Stage Venture

Investment Act of 2003 to promote Michigan’s

economic health by assisting in the creation

of jobs, new businesses and new industries

D I R E C TO RY & R E S O U R C E G U I D E


within the state. The VMF makes investments

ONLY in venture firms that invest primarily

in Michigan-based early stage companies.

www.venturemichigan.com

Federal Funding Opportunities are listed

in the SSTI Weekly Funding Supplement

offered by the federal government, founda-

tions and other industries.

www.ssti.org/Digest/supplement.htm

Michigan BiO-FOcUSed VENTURE AND ANGEL GROUPSann arbor angels www.annarborangels.org

apjohn Group, LLC www.apjohnventures.com

arbor Partners www.arborpartners.com

arboretum Ventures www.arboretumvc.com

ardesta, LLC www.ardesta.com

Beringea www.beringea.com

BioStar Ventures www.biostarfund.com

Bridge Street Capital www.bridgestreetcapital.com

Capital Community angels www.capitalcommunityangels.org

Dow Venture Capital www.dow.com/venture

eDF Ventures www.edfvc.com

entrepreneurs and Investors exchange www.EntrepreneurInvestorExchange.com

First angels www.swmfirst.com/First_Angels.cfm

Fletcher Spaght Ventures www.fletcherspaght.com/ventures

Grand angels www.grandangels.org

Great Lakes angels www.glangels.org

Great Lakes entrepreneur’s Quest www.gleq.org

Hartwick Capital www.hartwickcapital.com

Hopen Therapeutics www.hopentherapeutics.com

Midwest Venture Partners www.midwestvp.com

Michigan Venture Capital association www.michiganvca.org

North Coast technology Investors www.northcoastvc.com

Oracle Capital Partners, LLC www.oracle-capital.com

Plymouth Management Company www.plymouthvc.com

renaissance Venture Capital Fund www.renvcf.com

Seneca Partners www.senecapartners.com

Sigvion Capital www.sigvion.com

Southwest Michigan First Life Science Fund www.southwestmichiganfirst.com

tGap Ventures www.tgapventures.com

triathlon Medical Ventures www.tmvp.com

Wolverine Venture Fund www.zli.bus.umich.edu/wvf

UNIVERSITY RESEARCH AND TECHNOLOGY TRANSFERMichigan universities Commercializa-tion Initiative (MuCI) complements and

enhances technology transfer functions at

Michigan academic and research institutions

by supporting commercialization of Intel-

lectual Property.

www.muci.org

technology transfer Offices: l Central Michigan university www.orsp.cmich.edu

(989) 774-4000

l eastern Michigan university www.ord.emich.edu

(734) 487-3090

l Ferris State university www.ferris.edu

(231) 591-5983

l Grand Valley State university www.gvsu.edu/research_dev

(616) 331-2281

l Michigan State university http://www.oip.msu.edu/

(517) 355-2186

l Michigan technical university www.admin.mtu.edu/adv/cs/

(906) 487-2228

l Northern Michigan university webb.nmu.edu/Departments/TOS

(906) 227-2190

l Oakland university www2.oakland.edu/research

(248) 370-2552

l Saginaw Valley State university http://www.svsu.edu/cbed

(989) 964-4047

l university of Michigan www.techtransfer.umich.edu

(734) 763-0614

l Van andel research Institute www.vai.org

(616) 234-5000

l Wayne State university www.techtransfer.wayne.edu

(313) 577-5541

l Western Michigan university www. www.brcc.wmich.edu

(269) 544-1072



university research Corridor is an alli-

ance between Michigan’s three major research

universities to transform, strengthen and

diversify the state’s economy. The partners,

Michigan State University, the University of

Michigan and Wayne State University, spark

regional economic development via inven-

tion, innovation and technology transfer,

by educating a work force prepared for the

knowledge economy, and by attracting smart

and talented people to Michigan.

(734) 647-1844

ww.urcmich.org

SMARTZONES AND BUSINESS ACCELERATORS SmartZonestM provide distinct geographi-

cal locations where technology-based firms,

entrepreneurs and researchers locate in close

proximity to all of the community assets that

assist in their endeavors. SmartZoneTM tech-

nology clusters promote resource collabora-

tions between universities, industry, research

organizations, government and other

community institutions, growing technology-

based businesses and jobs. New and emerging

businesses in SmartZoneTM technology

clusters are primarily focused on commercial-

izing ideas, patents and other opportunities

surrounding corporate, university or private

research institute R&D efforts.

www.michigan.org/smartzones

l ann arbor/ypsilanti: Ann Arbor SPARK, University of Michigan, Eastern Michigan University 201 S. Division St., Suite 430 Ann Arbor, MI 48104 (734) 761-9317 www.AnnArborUSA.org Contact: Michael Finney

l automation alley Lawrence Institute of Technology, Oakland University Automation Alley Technology Center 2675 Bellingham Rd Troy, MI 48083 (248) 457-3200 www.automationalley.com Contact: Tom Anderson

l Battle Creek aviation & e-Learning Western Michigan University,

Kellogg Community College

4950 West Dickman Rd.

Battle Creek, MI 49037

(269) 962-7526

www.bcunlimited.org

Contact: Karl Dehn

l Detroit/Woodward technology Corridor: techtown Wayne State University

440 Burroughs, Entrepreneurial Suite

Detroit, MI 48202

(313) 879-5250

www.techtownwsu.org

Contact: Randal Charlton

l Grand rapids: West Michigan Science & technology Initiative Grand Valley State University,

Van Andel Institute

301 Michigan St NE, Suite 536

Grand Rapids, MI 49503

(616) 331-5840

www.wmsti.org

Contact: Rich Cook

l Houghton/Hancock: Michigan tech enterprise Corporation Michigan Technical University

Advance Technology Development

Complex

101 West Lakeshore Drive

Houghton, MI 49931

(906) 487-7000

www.mtecsmart.com

Contact: Carlton K. Crothers

l Jackson technology Park Baker College, Jackson Community

College, Spring Arbor University

One Jackson Square, Suite 1100

Jackson, MI 49201

(517) 788-4455

www.enterprisegroup.org

Contact: Scott Fleming

l Kalamazoo: WMu Business technology & research Park Western Michigan University

4717 Campus Drive, #100

Kalamazoo, MI 49008

(269) 353-1823

www.kazoosmic.com

Contact: Robert DeWit

l Lansing/east Lansing: university Corporate research Park 2727 Alliance Drive, Ste. C

Lansing, MI 48910

(517) 432-1753

ucrp.msu.edu

Contact: George Benson

l Macomb INCubator Oakland University

7205 Sterling Ponds Court

Sterling Heights, MI 48312

(586) 463-2542

www4.oakland.edu/macombouinc

Contact: David Spenser

l Midland: Mt. Pleasant SmartZonetM Satellite MidMichigan Innovation Center

4520 E. Ashman Rd., Suite M

Midland, MI 48642

(989) 839-2333

www.midmichiganinnovationcenter.org

Contact: Chris Moultrup

l Mt. Pleasant: Center for applied research & technology Central Michigan University

2625 Denison Drive

Mt. Pleasant, MI 48858

(989) 774-2424

www.cmurc.com

l Muskegon Lakeshore Grand Valley State University

380 W. Western Ave, Suite 202

Muskegon, MI 49440

(231) 724-6702

www.muskegonareafirst.org

Contact: Ed Garner


MichBio MeMBer AnnuAl corporAte SponSor preferred provider

For the most current list of companies, please visit the MichBio website at www.michbio.org.


lrochester Hills: Oakland university INCubator Oakland University Shotwell-Gustafson

Pavilion, Oakland University

2200 N. Squirrel Road

Rochester, MI 48309

(248) 648-4800

www.oakland.edu/ouinc

Contact: David Spencer

l Sault St. Marie Economic Development Corp.

1301 West Easterday Ave.

Sault Ste. Marie, MI 49783

(906) 635-9131

www.saultedc.com

Contact: Jim Hendricks

l Wayne County: Pinnacle aeropark University of Michigan, Wayne State

University, Detroit Metropolitan Airport

600 Randolph Street, Third Floor

Detroit, MI 48226

(313) 224-6076

www.waynecounty.com

Contact: Dave Tyler

SELECTED MICHIGAN COUNTY ECONOMIC DEVELOPMENT ORGANIZATIONSalcona

ww.alconacountymi.com

allegan www.allegancounty.org

Bay

www.baycounty-mi.gov/EACD/EconomicDe-

velopment.aspx

Benzie

www.benziecountyedc.com

Berrien

www.berriencounty.org

Calhoun

www.calhouncountymi.org

Genesee

www.thegrcc.org

Houghton

www.houghtoncounty.net

Ingham

www.ingham.org/DV/developm.htm

Ionia

www.icea-mi.org

Isabella

www.mmdc.org

Jackson

www.co.jackson.mi.us/JCinfo.asp

Kalamazoo

www.southwestmichiganfirst.com

Kent www.rightplace.org

Leelanau

www.leelanaucounty.com/edc.asp

Lenawee www.lenawee.mi.us

Livingston

www.livingstonedc.com

Manistee

www.allianceforeconomicsuccess.com

Marquette

www.marquette.org/economic_main.html

Macomb

www.macombcountymi.gov/MCPED

Mason

www.masoncountyedc.com

Midland

www.midlandtomorrow.org

Monroe www.monroecountyidc.com

Muskegon

www.muskegonareafirst.org

Newaygo

www.ncedo.org

Oakland

www.oakgov.com/peds

Ontonagon

www.ontcoedc.com

Otsego

www.otsego.org/econdev.htm

Ottawa www.co.ottawa.mi.us

Saginaw

www.saginawfuture.com

Sanilac

www.sanilaccounty.org

Schoolcraft www.schoolcraftedc.com

St. Clair

www.edascc.com

St. Joseph www.sjcedc.com

traverse Bay www.tcchamber.org

Van Buren www.vbco.org/econdev0003.asp

Washtenaw

www.AnnArborUSA.org

Wayne

www.waynecounty.com/jed

For a complete list of Michigan economic

development organizations, please visit

www.ecodevdirectory.com/Michigan.htm








AG-BIO/INDUSTRIAL

53

ag-BiO/indUStRial A.M. Todd 1717 Douglas Avenue Kalamazoo, 49007 269 343-2603 amtodd.com/flash_content.php

Abbott Nutrition 901 North Centerville Rd. Sturgis, 49091 269 651-0787 abbott.com

AEGIS Environments 2205 Ridgewood Dr. Midland, 48642 800 241-9186 microbeshield.com

Agrium 2405 Vassar Rd. Reese, 48757 989 752-2138 agrium.com

Algal Scientific Corp. 46701 Commerce Center Dr. Plymouth, 48170 734 218-5717 algalscientific.com

Bayer CropScience 1740 N. Whitehall Muskegon, 49445 231 719-3000 bayercropscience.com

Bio-lab, Inc. 1400 East Michigan St. Adrian, 49221 517 265-6138 chemtura.com

Bio-Nano Power, LLC 2625 Denison Dr. Mt. Pleasant, 48858 616 682-0367 N/A

Biotectix 3550 W. Liberty Rd., Ste. 3 Ann Arbor, 48103 734 995-9089 biotectix.com

BoroPharm, Inc. 39555 Orchard Hill Place, Ste. 600 Novi, 48375 888 366-1496 boropharm.com

Bridge Organics Co. 311 West Washington St. Vicksburg, 49097 616 649-4200 bridgeorganics.com

Burdick & Jackson 1953 S. Harvey St. Muskegon, 49442 231 726-3171 bandj.com

Caltech Industries, Inc. 4520 East Ashman Rd., Ste. C Midland, 48642 989 496-3110 caltechind.com

Cerise Nutraceuticals, Inc. 1670 Barlow St., Ste. A Traverse City, 49686 231 933-3300 cherrylotion.com

Chemtura 1400 East Michigan St. Adrian, 49221 517 265-6138 chemtura.com

Dendritech, Inc. 3110 Schuette Dr. Midland, 48642 989 496-2016 dendritech.com

Dendritic Nanotechnologies, Inc. 2625 Denison Dr., Ste. B Mt. Pleasant, 48858 989 774-6565 dnanotech.com

Diversified Natural Products 506 East State St. Scottville, 49454 231 757-9241 dnpworld.com

Draths Corp. 2367 Science Parkway, Ste. 2 Okemos, 48864 517 349-0669 drathsCorp..com

EcoSynthetix 3900 Collins Rd. Lansing, 48910 517 336-4649 ecosynthetix.com

Elan Nutrition 4490 44th St. Southeast Grand Rapids, 49512 616 940-6000 elannutrition.com

Emerald BioAgriculture Corp. / Auxein Corp. 2123 University Park Dr., Ste. 105 Okemos, 48864 517 882-7370 emeraldbio.com

GANTEC, Inc. 4520 East Ashman Rd., Ste. A Midland, 48642 877 816-9300 gantecinc.com

Gerber Product Company 445 State St. Fremont, 49413 231 928-2000 gerber.com/

Graminex, LLC 95 Midland Rd. Saginaw, 48638 877 472-6469 graminex.com

H2 EnviroFuel PO Box 36129 Grosse Pointe Shores, 48239 910 232-7601 N/A

Haviland Enterprises 421 Ann NW Grand Rapids, 49504 800 456-1134 havilandusa.com

HealthCure, LLC 390 Park St., Ste. 110 Birmingham, 48009 248 282-9300 healthcure.biz

Healthtreat, Inc. 30777 Northwestern Highway, Ste. 300 Farmington Hills, 48334 248 855-0033 healthtreat.com

Horseshoe Herbals 1219 Anderson Rd. Niles, 49120 269 684-6888 horseshoeherbals.com

Idea Sphere, Inc. 3133 Orchard Vista Dr SE Grand Rapids, 49546 616 464-5000 ideasphereinc.com

Intermediary Biochemicals, LLC 2529 Dustin Rd. Okemos, 48864 N/A N/A

J. Rettenmaier, USA 16369 US Highway 131 Schoolcraft, 49087 877 895-4099 jrsusa.com

Kalsec, Inc. PO Box 5051 Kalamazoo, 49005 269 349-9711 kalsec.com

Kellogg Company One Kellogg Square, PO Box 3599 Battle Creek, 49016 800 962-1413 kelloggcompany.com

Koppert Biological Systems, Inc. 2856 South Main St. Ann Arbor, 48103 734 641-3763 koppert.com

KTM Industries 3327 Ranger Rd. Lansing, 48906 517 703-9140 ktmindustries.com

Labtech Industries 7707 Lyndon Detroit, 48238 313 862-1737 N/A

Mayaterials 661 Airport Blvd., Ste. 1 Ann Arbor, 48108 734 994-7035 mayaterials.com

MBI International 3900 Collins Rd. Lansing, 48910 517 337-3181 mbi.org

Mead Johnson Nutrition 725 E. Main St. Zeeland, 49464 812 429-5000 meadjohnson.com

Microcide, Inc. 2727 Second Ave. #334 Detroit, 48201 888 342-6279 microcide.com

Nanosystems 3588 Plymouth Rd., Ste. 326 Ann Arbor, 48105 734 274-0020 N/A

Neogen Corp. 620 Lesher Place Lansing, 48912 800 234-5333 neogen.com

Next Generation Therapeutics, Inc 46701 Commerce Center Dr., Ste. A-6 Plymouth, 48170 734 527 9139 nextgenerationtherapeutics.com

Nitrate Elimination Company, Inc. 334 Hecla St. Lake Linden, 49945 906 296-1000 nitrate.com

Orthopedic Development, Inc. 6565 West Main St. Kalamazoo, 49009 269 544-4715 N/A

PVS Chemicals, Inc. 10900 Harper Ave. Detroit, 48213 313 921-1200 pvschemicals.com

ReNew Systems 1009 S. Henry St., PO Box 1072 Bay City, 48706 989 892-4552 renewsystems.com

SPI Pharma PO Box 226 Grand Haven, 49417 231 935-6900 spipharma.com

SubTerra LLC PO Box 55, 104 Wilcox Rd. White Pine, 49971 906 885-5953 subterrallc.com

Superior Growers Supply 4870 Dawn Ave. East Lansing, 48823 800 227-0027 superiorgrowers.com

The Dow Chemical Company 2030 Dow Center Midland, 48674 800 258-2436 dowventurecapital.com

Thorn Smith Laboratories 7755 Narrow Gauge Rd. Beulah, 49617 231 882-4672 thornsmithlabs.com

Thumb Oilseed Producers 2145 Leppek Rd. Ubly, 48475 989 658-2344 thumboilseed.com

Troy Polymers 330 E. Maple, Ste. L Troy, 48083 248 733-1030 troypolymers.com

BIOSCIeNCeS





BIOSCIENCES CONTINUED

ag-BiO/indUStRial cOntinUedUckele Health and Nutrition P.O. Box 160 Blissfield, 49228 800 248-0330 uckele.com

Van Beek Nutrition 3537 West YZ Ave. Schoolcraft, 49087 269 679-5441 vanbeeknutrition.com

Vertellus Health and Specialty Products, LLC 215 North Centennial St. Zeeland, 49464 800 223-0453 vertellus.com

Vestaron Corp. 4717 Campus Dr., Ste. 1200 Kalamazoo, 49008 269 372-8745 vestaron.com

Wacker Chemical Corp. 3301 Sutton Rd. Adrian, 49221 517 264-8793 wacker.com

Working Bugs, LLC 16647 Chandler Rd. East Lansing, 48823 517 203-4744 workingbugs.com

XG Sciences, Inc. 5020 Northwind Dr., Ste. 212 East Lansing, 48823 517 203-1110 xgsciences.com

INFORMATION TECHNOLOGYAltarum Institute 3520 Green Ct., Ste. 300, PO Box 134001 Ann Arbor, 48105 734 302-4600 altarum.org

Arivium, Inc. 354 Glen Arbor Dr. NE Rockford, 49341 616 292-5018 arivium.com

Avicenna Medical Systems, Inc. 3090 Dhu Varren Ct. Ann Arbor, 48105 888 284-4080 avicenna-medical.com

Better Rehab, LLC 1170 Morehead Ct. Ann Arbor, 48104 734 604-1966 N/A

BioMedware Inc. 3526 W. Liberty Rd., Ste. 100 Ann Arbor, 48103 734 913-1098 biomedware.com

BioPharma Data Services 1461 Scio Ridge Ct. Ann Arbor, 48103 734 255-1038 BioPharmaDataServices.com

BlueWare, Inc. 3060 West 13th St. Cadillac, 49601 231 779-0224 blueware.net

Cielo MedSolutions 3520 Green Court, Ste. 150 Ann Arbor, 48105 734 827-1000 cielomedsolutions.com

Coherix, Inc. 3980 Ranchero Dr. Ann Arbor, 48108 734 922-4066 coherix.com

Compendia Bioscience 110 Miller Ave., Fl. 2 Ann Arbor, 48104 734 929-3909 compendiabio.com

Concepts in Software 455 Woodland Hills Dr. Walled Lake, 48390 734 730-4692 conceptsinsoftware.com

Contented Hearts, Inc. 11490 East G Ave. Galesburg, 49053 269 665-4420 contentedhearts.com

Critech Research, Inc. 1705 Woodland Dr. East, Ste. 100 Saline, 48176 734 668-0005 critech.com

Cybernet Medical 727 Airport Blvd. Ann Arbor, 48108 800 292-3763 cybernetmedical.com

Data Integrated Scientific Systems 8031 Main St., Ste. 301 Dexter, 48130 734 426-4995 dissdata.com

DataSpeaks, Inc. 2971 Vineyards Dr. Troy, 48098 248 952-1968 dataspeaks.com

DDots, Inc. 4571 Ellsworth Rd. Ypsilanti, 48197 734 434-7734 ddots.com

Dermanaut 702 Dwight St. Ypsilanti, 48198 734 604-8214 dermanaut.com

DNA Software, Inc. 334 East Washington St. Ann Arbor, 48104 734 222-9080 dnasoftware.com

GE Medical Systems Information Technology 3300 Washtenaw Ave., Ste. 225 Ann Arbor, 48104 N/A gehealthcare.com/usen/hit/index.html

Gene Codes 775 Technology Dr., Ste. 100 Ann Arbor, 48108 734 769-7249 genecodes.com

GeneGo, Inc. 500 Renaissance Dr., Ste. 106 St. Joseph, 49085 888 592-3124 genego.com

Genetics Squared, Inc. 401 West Morgan Rd. Ann Arbor, 48108 734 929-9475 genetics2.com

Genomatix Software, Inc. 3025 Boardwalk, Ste. 160 Ann Arbor, 48108 877 436-6628 genomatix-software.com

HealthMedia, Inc. 130 South First St. Ann Arbor, 48104 734 623-0000 healthmedia.com

InformMed 1710 Hermitage Rd. Ann Arbor, 48104 734 332-0612 informmed.com

Integrated Nonclinical Development Solutions, Inc. (INDS) 3005 Miller Ave. Ann Arbor, 48103 734 929-5392 INDS-Inc.com

INVIA Medical Imaging Solutions 3025 Boardwalk St., Ste. 200 Ann Arbor, 48108 734 205-1231 inviasolutions.com

Johnson & Johnson P.O. Box 726 Langhorne, PA 19047 N/A jnj.com

McKesson Pharmacy Systems 30881 Schoolcraft Livonia, 48150 734 779-8800 mckesson.com

MedElephant, Inc. 21700 Northwestern Hwy, Ste. 110 Southfield, 48075 N/A medelephant.com

MedImage, Inc. 6276 Jackson Road, Suite G Ann Arbor, 48103 734 665-5400 medimage.com

MERS, LLC 799 Skynob Dr. Ann Arbor, 48105 734 487-1251 mersllc.com

MetagenX, LLC 4316 Aztec Way Okemos, 48864 517 203-0194 N/A

NeuMedicine PO Box 756 Novi, 48376 877 563-8633 neumedicine.com

Nutriinfo.com 41850 W. 11 Mile Rd., Suite 106 Novi, 48375 866 533-7172 nutriinfo.com

POLY Bioinformatics 12191 E. Austin Rd. Manchester, 48158 734 678-7342 polyergic.com

Qtox, LLC 1828 Yosemite Dr. Okemos, 48864 N/A N/A

ScreenTrack 1603 Peach St. Ann Arbor, 48105 734 665-0701 N/A

Sentry Medical Technologies 1039 Olivia Ave. Ann Arbor, 48104 734 476-8502 N/A

Therapy Charts 228 Nickels Arcade Ann Arbor, 48104 866 288-9758 therapycharts.com

Thomson Reuters 777 East Eisenhower Pkwy. Ann Arbor, 48108 734 913-3000 thomsonreuters.com

Toxicogenomic Informatics and Solutions, LLC PO Box 27482 Lansing, 48909 N/A txisllc.com

Unival, Inc. 2100 Commonwealth Blvd., Ste. 300 Ann Arbor, 48105 800 332-4463 unival-med.com

Versus Technology, Inc. 2600 Miller Dr. Traverse City, 49684 231 946-5868 versustech.com

XB Transmed Solutions 3133 Orchard Vista Dr. SE Grand Rapids, 49546 616 234-5586 xbtransmed.com

YourSurgery.com 7171 First St. West Bloomfield, 48324 248 858-2606 yoursurgery.com







55

MEDICAL DEVICESAccess Medical LLC 1717 Shaffer St., #107 North Professional Bldg. Kalamazoo, 49048 269 276-0068 accessmedicaldirect.com

Accord Biomaterials, Inc. 3550 W. Liberty Rd., Ste. 3 Ann Arbor, 48103 734 995-9089 accordbiomaterials.com

Accumed Systems Inc. 6111 Jackson Road, Ste. 102 Ann Arbor, 48103 734 930-0461 accumedsystemsinc.com

Accuri Cytometers, Inc. 173 Parkland Plaza Ann Arbor, 48103 734 994-8000 AccuriCytometers.com

Adamlab, LLC 55 East Long Lake Rd., Ste. 337 Troy, 48085 248 362-9603 adamlab.com

Advanced Photonix Inc. 2925 Boardwalk Ann Arbor, 48104 734 864-5639 advancedphotonix

AI Medical Devices, Inc. 311 Turner Rd. Williamston, 48895 517 881-8804 aimedicaldevices

Air Force Inc. 933 Butternut Dr. Holland, 49424 616 399-8511 dentalairforce.com

Akervall Technologies 5643 Plymouth Rd. Ann Arbor, 48105 734 485-2949 akervalltechnologies.com

Alivio Corporation 20429 Honor Hwy. Interlochen, 49643 231 275-1345 aliviocorp.com

American Dental Technologies, Inc. 28265 Beck Rd., Ste. C-22 Wixom, 48393 800 359-1959 americandentaltech.com

Amigo Mobility International 6693 Dixie Hwy. Bridgeport, 48722 989 921-5062 myamigo.com

Angott Medical Products, LLC 442 Five Gaits Ct. Bloomfield Hills, 48304 248 444-1492 N/A

AquaBiochip, LLC 1012 North Walnut St., Ste. 101 Lansing, 48906 517 402-2692 aquabiochip.com

ASI Instruments, Inc. 12900 E. Ten Mile Rd. Warren, 48089 586 756-1222 asi-instruments.com

Aspen Surgical Products, Inc. 6945 Southbelt SE Caledonia, 49316 888 364-7004 aspensurgical.com

ATEK Medical Manufacturing 620 Watson SW Grand Rapids, 49504 616 643-5200 atekcompanies.com

Ateq Corporation 42000 Koppernick Rd. Canton, 48187 734 451-9449 atequsa.com

Autocam Medical 4436 Broadmoor SE Kentwood, 49512 800 747-6978 autocam-medicalkk.com

AVAcore Technologies 333 Parkland Plaza Dr., Ste. 700 Ann Arbor, 48103 888 282-2673 avacore.com

Avalon Laboratories LLC 301 Michigan St., Ste. 500 Grand Rapids, 49503 616 331-5843 avalonlabs.com

Axsys Technologies, Inc. 2909 Waterview Dr. Rochester Hills, 48309 248 293-2900 axsys.com

Azenic Dental, Inc. 259 East Michigan Ave., Ste. 409 Kalamazoo, 49007 269 349-8870 N/A

B.A. Maze, Inc. 43311 Joy Rd. Canton, 48187 734 459-5747 purrfectopener.com

BarbLock 11590 S. US-31 Williamsburg, 49690 231 264-0101 barblock.com

BD Diagnostics (formerly HandyLab Inc.) 5230 S. State Rd. Ann Arbor, 48108 734 663-4719 handylab.com

Becker Orthopedic 635 Executive Drive Troy, 48083 248 588-7480 beckerorthopedic.com

Bio Logic Engineering, Inc. 1675 N. Lima Center Rd. Dexter, 48130 734 433-9256 biologicengineering.com

Bio-Coat, Inc. 21249 Bridge St. Southfield, 48034 248 352-4570 N/A

BioLumix, Inc 104 Aprill Dr. Ann Arbor, 48103 734 984-3100 mybiolumix.com

Biophotonic Solutions, Inc. 3590 Breezy Point Dr. Okemos, 48864 517 881-4562 biophotonicsolutions.com

BioPro 2929 Lapeer Rd. Port Huron, 48060 810 982-7777 bioproimplants.com

Birchbrook Technologies L.L.C. 53470 Andrew Circle New Baltimore, 48047 586 648-8267 birchtek.com

Blaze Medical Devices 9146 Dexter Pinckney Rd. Pinckney, 48169 734 945-7764 N/A

Bremer Prosthetics, Inc. G3487 S. Lindin Rd., Ste. U Flint, 48507 810 733-3375 bremerprosthetics.com

Brenner Orthotic and Prosthetic Labs 32975 West Eight Mile Rd. Livonia, 48152 810 615-0601 N/A

CardiArc 7444 Haggerty Rd. Canton, 48187 734 207-3440 cardiarc.com

Cascade Life Solutions 3710 Sysco Ct., SE Grand Rapids, 49512 616 977-2515 N/A

CFI Medical Solutions (Contour Fabricators, Inc.) 14241 Fenton Rd. Fenton, 48430 810 750-5300 cfimedical.com

Christian Roux Ltd. 598 E. Grand Blvd. Ypsilanti, 48198 734 732-6671 hurricanecrutch.com


College Park Industries 17505 Helro Rd. Fraser, 48026 586 294-7950 college-park.com

Compendia Bioscience 110 Miller Ave., Fl. 2 Ann Arbor, 48104 734 929-3909 compendiabio.com

Conceivex PO Box 31, 5 East Main St. Saranac, 48881 616 452-2700 conceptionkit.com

Corium International, Inc. 4558 50th St. Grand Rapids, 49512 616 656-4563 coriumintl.com

Covalent Medical, Inc. 4750 S. State St., Ste. 301 Ann Arbor, 48108 734 429-2451 covamed.com

Coy Laboratory Products Inc. 14500 Coy Drive Grass Lake, 49240 734 475-2200 coylab.com

CPR Mattress 200 Michigan St. Hancock, 49930 906 483-2676 cprmattress.com

Critical Signal Technologies 22600 Haggerty Road Farmington Hills, 48335 888 557-4462 criticalsignaltechnologies.com

Custom Biogenic Systems 150 Shafer Dr. Romeo, 48065 586 331-2600 custombiogenics.com

CVR Global, Inc. 18186 Parke Lane Grosse Ile, 48138 734 604-6023 cvrglobal.com

Cybernet Medical, Cybernet Systems Corporation 727 Airport Blvd. Ann Arbor, 48108 800 292-3763 cybernetmedical.com

CytoPherx 401 W Morgan Ann Arbor, 48108 734 272-4772 cytopherx.com

Danmar Products Inc. 221 Jackson Industrial Dr. Ann Arbor, 48103 800 783-1998 danmarproducts.com

Data Integrated Scientific Systems 8031 Main St., Ste. 301 Dexter, 48130 734 426-4995 dissdata.com






56


MEDICAL DEVICES CONTINUEDDavis Dental Labs 5830 Crossroad, Commerce Parkway Wyoming, 49519 616 261-9191 dentalservices.net/davis

DavisMade, Inc. 2511 Davison Rd. Flint, 48506 810 742-0581 standingdani.com

Diagnostic Instruments Inc. 6540 Burroughs St. Sterling Heights, 48314 586 731-6000 diaginc.com

Diamond General 333 Parkland Plaza Dr. Ann Arbor, 48103 800 678-9856 diamondgeneral.com

Digilab Genomic Solutions 4355 Varsity Dr., Ste. E Ann Arbor, 48108 734 975-4800 genomicsolutions.com

DNADNB LLC 4995 Arrowhead Rd. West Bloomfield, 48323 248 682-3368 N/A

DuPeron Medical Systems 515 N. Washington Ave. Saginaw, 48607 800 383-8479 duperon.com

EADevices, Inc. 7752 Primrose Lane Portage, 49024 412 334-7045 eadevices.com

ECO PHYSICS, INC. 3915 Research Park, Suite A-3 Ann Arbor, 48108 734 998-1600 ecophysics-us.com

EdgeHealth LLC 217 Third Street Ann Arbor, 48103 734 622-8060 N/A

Ennew Medical Devices, LLC 2400 N. 6th Street Kalamazoo, 49009 269 615-5113 N/A

Epsilon Imaging Inc. 3917 Research Park Drive, Suite B7 Ann Arbor, 48108 734 369-5100 epsilon-imaging.com

Essen Bioscience 1156 Oak Valley Drive Ann Arbor, 48108 734 769-1600 essen-instruments.com

EyeLab Group 2350 Washtenaw, Suite 4 Ann Arbor, 48104 734 665-0567 N/A

FlowTech Corporation 7601 Stadium Drive Kalamazoo, 49009 269 375-1290 flowtechfilters.com

Fluid Insights LLC 4995 Arrowhead Road West Bloomfield, 48323 248 682-3368 N/A

Freeman Manufacturing Company 900 W. Chicago Rd. Sturgis, 49091 616 651-2371 freemanmfg.com

Garrison Dental Solutions 150 DeWitt Lane Spring Lake, 49456 616 842-2430 garrisondental.com

Gema Diagnostics 463 Rosewood Avenue East Lansing, 48823 517 775-3007 gemadiagnostics.com

Grant Manufacturing Corporation 10957 Old 27 Hwy N. Vanderbilt, 49795 989 983-3641 granthealingenvironment.com

Green BioWorks 330 East Liberty St., Lower Level Ann Arbor, 48104 734 276-4764 greenbioworks.com

HAC of America, Inc. 1111 West Centre Ave. Kalamazoo, 49024 800 445-9968 hacofamerica.com

Hamztec LLC 1039 Olivia Ave. Ann Arbor, 48104 734 476-8502 N/A

Hanger Prosthetics & Orthodics 2314 Gull Road Kalamazoo, 49001 269 345-1117 hanger.com

Hart Enterprises 400 Applejack Court Sparta, 49345 616 887-0400 hartneedles.com

Haworth, Inc. One Haworth Center Holland, 49423 616 393-3000 haworth.com

Helvetia Development Company LLC 225 Parsons Street Kalamzoo, 49007 877 626-5704 conformamed.com

Herman Miller Inc 855 East Main Ave., PO Box 302 Zeeland, 49464 616 654-3000 hermanmiller.com

HistoSonics, LLC 7819 Kilbirnie Drive Portage, 49024 269 270-4387 N/A

HoMedics 3000 North Pontiac Trail Commerce Twp, 48390 248 863-3000 homedics.com

Hygieia, Inc. 330 E. Liberty Street, Lower Level Ann Arbor, 48104 734 527-9160 N/A

Implants International N.A. 220 E. Huron St., 3rd Floor Ann Arbor, 48104 N/A implantsinternational.com

In the Groove, LLC 7600 Madeline Street Saginaw, 48609 517 781-6030 inthegroovebrace.com

Incept BioSystems 401 W. Morgan Rd. Ann Arbor, 48108 317 508-6972 inceptbio.com

InnerSpace Corporation P.O. Box 2186 Grand Rapids, 49501 616 224-2828 stanleyinnerspace.com

InnoMotus LLC 3710 Frains Lake Ann Arbor, 48105 N/A N/A

Innovational Therapeutics 1404 Cambridge Road Ann Arbor, 48104 734 914-0550

Innovative BioTherapies, Incorporated 401 W. Morgan Rd. Ann Arbor, 48108 734 213-8350 innbio.com

INRAD, Inc. 4375 Donker Ct. SE Kentwood, 49512 616 301-7800 inrad-inc.com

Integrated Sensing Systems (ISSYS) 391 Airport Industrial Drive Ypsilanti, 48198 734 547-9896 mems-issys.com

INVIA Medical Imaging Solutions 3025 Boardwalk Street, Suite 200 Ann Arbor, 48108 734 205-1231 inviasolutions.com

IPGDx LLC P.O. Box 253 Harrisville, 48740 989 724-5631 ipgdx.com


KOA Orthopedics 46985 Enterprise Drive, Suite A-100 Wixom, 48393 248 596-0250 koaorthopedics

Koch’s Orthotics and Prosthetics 5315 Elliot Drive, Suite 104 Ypsilanti, 48197 734 434-0442 N/A

Lake Erie Wholesale Medical Supply 7560 Lewis Avenue Temperance, 48182 734 847-3847 N/A

LaMed, Inc 54283 Meadowood Court, Suite 610 Shelby Township, 48316 248 650-0476 lamedinc.com

Laser Mechanisms, Inc. / Oxid Corporation 25275 Regency Dr. Novi, 48375 248 474-9817 Oxid.com

LDI Incorporated, ETO MAGNETIC Corp., LDI, Inc. 4311 Patterson S.E. Grand Rapids, 49512 N/A ldiinc.com

Life Magnetics N/A Ann Arbor 734 277-2378 lifemagnetics.com

Lift Aid 50714 Century Ct. Wixom, 48393 248 348-1000 liftaid.com

Lodox PTY LTD 23360 Clarkshire South Lyon, 48178 248 446-8480 lodox.com

L-VAD Technologies, Inc. 300 River Place, Suite 6850 Detroit, 48207 313 446-2800 lvadtech.com

Lynn Medical Instruments P.O. Box 930459 Wixom, 48393 248 560-4500 lynnmed.com

Mager Scientific 1100 Baker Rd. Dexter, 48130 734 426-3885 magersci.com

MarketLab P.O. Box 888374 Kentwood, 49588 616 656-2484 marketlabinc.com

MedArray, Inc. 3915 Research Park Dr., Suite A-4 Ann Arbor, 48108 734 769-1066 permselect.com







57

MEDICAL DEVICES CONTINUEDMedBio, Inc. 630 S. Division Ave. Grand Rapids, 49503 616 245-0214 medbioinc.com

MedElute, Inc. 259 East Michigan Ave., Suite 407 Kalamazoo, 49007 269 352-3760 N/A

Medical Accessories & Research Corporation 219 North Church Street Zeeland, 49464 616 748-8950 medacc.com

Medical Imaging Resources, Inc. 120 Enterprise Dr. Ann Arbor, 48103 734 426-3003 mobileleasing.com

MedImage, Inc. 6276 Jackson Road, Suite G Ann Arbor, 48103 734 665-5400 medimage.com

Medi-Nuclear Corp. 3029 Research Dr. New Hudson, 48165 800 423-4266 medinuc.com/index.html

MediQuest Life Sciences, LLC 42030 Koppernick Road Canton, 48187 734 455-7110 mediquestlifesciences.com

Medtronic 620 Watson Street SW Grand Rapids, 49504 616 242-5200 medtronic.com

MemsTech 42503 Steepleview Northville, 48167 734 560-5506 memstech.com


MI4Spine, LLC 1070 Timberlake Dr. Bloomfield Hills, 48302 248 535-6953 mi4spine.e-shopmall.com

Michigan Critical Care Consultants, (MC3) Inc. 3550 W. Liberty, Suite 3 Ann Arbor, 48103 734 995-9089 mc3corp.com

Michigan Instruments 4717 Talon Ct. SE Grand Rapids, 49512 616 554-9696 michiganinstruments.com

Michigan Orthodontic Appliances 1013 East 3rd Street Royal Oak, 48067 248 544-0860 N/A

Michigan Orthopedic Services 13450 Farmington Road Livonia, 48150 734 513-8205 michortho.com

Michigan Surgical Equipment LLC 48797 West Road Wixom, 48393 248 349-5859 michigansurgical.com

Micro Machine Company 2429 North Burdick St. Kalamazoo, 49007 269 388-2440 micromachineco.com

Midbrook, Inc. 2080 Brooklyn Rd. Jackson, 49203 517 787-3481 midbrook.com

Miller Technical Services 7444 Haggerty Rd. Canton, 48187 734 207-2600 ctsmius.com

Mitchell Home Medical 3430 Washtenaw Ann Arbor, 48104 734 477-0202 mitchellhomemedical.com

Monteris Medical, Inc. 4664 Campus Drive Kalamazoo, 49008 269 372-0455 monteris.com

Mt. Clemens Orthopaedic Appliances, Inc. 24432 Crocker Blvd. Clinton Township, 48036 586 463-3600 N/A

M-Vision 12420 Stanley Drive Belleville, 48111 734 697-3933 m-visioninc.com

Nalge Nunc International 9680 Oakhill Rd. Holly, 48442 248 842-8620 nalgenunc.com/default.asp

Nanoderm Therapeutics, Inc. 3081 N. Foxridge Ct. Ann Arbor, 48105 734 665-4105 N/A

NeuroNexus Technologies, Inc. 3985 Research Park Drive, Suite 100 Ann Arbor, 48108 734 913-8858 neuronexustech.com

Next Generation Therapeutics, Inc 46701 Commerce Center Dr., Suite A-6 Plymouth, 48170 734 527-9139 nextgenerationtherapeutics.com

NEXT Mobility 7444 Haggerty Rd. Canton, 48187 888 489-6398 nextmobilitynow.com

Northwest Orthotics-Prosthetic, Inc. 39830 Grand River, Suite BLD Novi, 48375 248 477-1443 N/A

Norwind-Cortez 305 North Hewitt Ypsilanti, 48197 734 434-0575 N/A

NuStep 5111 Venture Drive, Ste. 1 Ann Arbor, 48108 734 769-3939 nustep.com

OcuSciences, Inc. 3201 Asher Rd. Ann Arbor, 48104 734 646-4156 ocusciences.com

Omega Surgical Instruments, Inc. G-8395 S. Saginaw Street Grand Blanc, 48439 800 656-6342 omegasurgical.com

Oncologix Tech P.O. Box 8832 Grand Rapids, 49518 616 977-9933 N/A

Optical Dimensions 711 East 4th Street Royal Oak, 48067 248 541-3790 opticaldimensionslab.com/default.aspx

Optical Supply 1526 Plainfield Ave, NE Grand Rapids, 49505 616 361-6000 optical-supply.com

Orchid Bio-Coat Orthopedic Solutions 21249 Bridge Street Southfield, 48034 248 352-4570 orchid-orthopedics.com/biocoat

Orchid Bio-Vac Orthopedic Solutions 21316 Bridge Street Southfield, 48033 248 350-2150 orchid-orthopedics.com/biovac

Orchid Stealth 1489 Cedar St. Holt, 48842 517 694-2300 orchid-orthopedics.com

Orchid Unique Orthopedic Solutions 6688 Dixie Highway Bridgeport, 48772 989 746-0780 orchid-orthopedics.com/unique

Orthopedic Development, Inc. 6565 West Main St. Kalamazoo, 49009 269 544-4715 N/A

Ostial Solutions 1111 Short Road Kalamazoo, 49008 269 383-3797 ostialsolutions.net

Pall Corporation - Life Sciences 600 S. Wagner Road Ann Arbor, 48103 800 521-3160 pall.com

PBS Biotech 2843 E. Grand River Avenue, Suite 262 Okemos, 48823 N/A pbsbiotech.com

Performace Systematix Inc. 5569 33rd Street, SE Grand Rapids, 49512 616 949-9090 psix.com

Phadia US 4169 Commercial Avenue Portage, 49002 800 346-4364 phadia.us

Physician Technology, LLC 23 East Front Street Monroe, 48161 419 944-8722 willomd.com

PICOCAL 333 Parkland Plaza Ann Arbor, 48103 N/A picocal.com

Pioneer Surgical Technology 375 River Park Circle Marquette, 49855 906 226-9909 pioneersurgical.com

Pixel Velocity Inc. 3917 Research Park Drive Suite 1B Ann Arbor, 48108 734 213-3715 pixel-velocity.com

Plas-Labs, Inc. 401 E. North Street Lansing, 48906 517 372-7177 plas-labs.com

Precision Edge Surgical Products 415 W. 12th Avenue Sault Ste Marie, 49783 906 632-4800 precisionedge.com

Progressive Dynamics Medical 507 Industrial Road Marshall, 49068 269 781-4241 progressivedynamicsmedical.com

Pros-Tech 1717 Stephenson Hwy. Troy, 48083 248 680-2800 pros-tech.com

Prosthetic Center, Inc 1200 S. Washington Avenue Lansing, 48910 517 372-7007 N/A

Proud Mary Prosthetics 6305 Wall St. Sterling Heights, 48312 877 627-9272 proudmaryprosthetics.com






58


MEDICAL DEVICES CONTINUEDRanir, LLC 4701 East Paris Avenue SE Grand Rapids, 49518 616 698-8880 ranir.com

Rapid BioSense 3900 Collins Road Lansing, 48910 800 579-4913 rapidbiosense.com

RealBio Technology, Inc. 4717 Campus Drive, Suite 1500 Kalamazoo, 49008 269 544-1088 realbiotechnology.com

Renko Enterprises, LLC 25344 Carollton Drive Farmington Hills, 48335 248 342-6472 N/A

RG Medical Diagnostics 28351 Beck Rd., Suite G5 Wixom, 48393 888 596-9498 rgmd.com

Richard-Allan Scientific 4481 Campus Dr. Kalamazoo, 49008 616 644-2400 rallansci.com

Rigaku Innovative Technologies 1900 Taylor Road Auburn Hills, 48326 248 232-6400 rigaku.com

RJL Systems, Inc. 33939 Harper Avenue Clinton Township, 48035 586 790-0200 rjlsystems.com

Rockwell Medical Technologies, Inc. 30142 Wixom Road Wixom, 48393 800 449-3353 rockwellmed.com

Rose Technologies 1440 Front Avenue NW Grand Rapids, 49504 616 233-3000 rose-technologies.com

Roush Life Sciences 12447 Levan Livonia, 48150 734 779-7006 roush.com

Rubicon Genomics, Inc. 4355 Varsity Drive, Suite E Ann Arbor, 48108 734 677-6210 rubicongenomics.com

RxDispense, Inc. 2706 Cumberland Berkley, 48072 734 277-0668 rxdispense.com

Sakor Technologies, Inc. 2855 West Jolly Rd. Okemos, 48864 517 332-7256 sakor.com

Selective Technologies, Inc. 132 West First St. Flint, 48502 810 767-7530 N/A

SenSound, LLC 440 Burroughs St., Suite 170 Detroit, 48202 313 882-1065 sensound.com

Siemens Ultrasound Division 400 W. Morgan Ann Arbor, 48108 734 995-5010 usa.siemens.com

Signal Medical Corporation 400 Pyramid Marysville, 48040 810 364-7070 signalmd.com

SkinTreet, LLC 1120 Olivia Avenue Ann Arbor, 48104 734 663-5999 N/A

Skytron 5085 Corporate Exchange Blvd. Grand Rapids, 49512 800 759-8766 skytron.us

Slaughter Instrument Co. 4356 North Roosevelt Stevensville, 49127 269 428-7471 slaughtercoinc.com

SoloHill Engineering, Inc. 4370 Varsity Drive, Suite B Ann Arbor, 48108 734 973-2956 solohill.com

Somanetics Corporation 2600 Troy Center Dr. Troy, 48084 248 244-1400 somanetics.com

Sonetics Ultrasound, Inc. 3550 W. Liberty, Ste. 3 Ann Arbor, 48103 734 260-4800 N/A

Sononir Technology LLC N/A Muskegon N/A N/A

Spartan Medical Supply 50762 Kiawah Trail Mattawan, 49071 866 894-5118 spartanmedicalsupply.com

Stryker Corporation 2825 Airview Boulevard Kalamazoo, 49002 616 385-2600 stryker.com

Stryker Instruments 4100 East Milham Avenue Kalamazoo, 49001 269 323-7700 stryker.com/instruments

Stryker Interventional Pain 2825 Airview Boulevard Kalamazoo, 49002 269 385-2600 stryker.com/en-us/products/ PainManagement/index.htm

Stryker Orthopaedics 44736 Helm St. Plymouth, 48170 734 454-0023 stryker.com/en-us/corporate/ContactUs/ Orthopaedics/index.htm

Stryker Osteosynthesis 2825 Airview Boulevard Kalamazoo, 49002 osteosynthesis.stryker.com

Surge Medical Solutions 3710 Sysco Ct. SE Grand Rapids, 49512 616 949-2392 surgemedical.com

SurgiTel 77 Enterprise Drive Ann Arbor, 48103 734 996-9200 surgitel.com

Symmetry Jet 5212 Aurelius Road Lansing, 48911 517 882-4311 symmetrymedical.com

Systems Specialties 390 Enterprise Court, Suite 200 Bloomfield Hills, 48302 248 332-0099 sysspec.com

Tangent Medical Technologies, LLC 2132 Packard St. Ann Arbor, 48104 800 664-7612 tangentmedical.com

Tech Initiatives Inc. 200 Michigan Street, Suite 408 Hancock, 49930 906 483-2676 cprmattress.com

Teclab 6450 Valley Industrial Drive Kalamazoo, 49009 269 372-6000 teclab.com

Tekna 3400 Tech Circle Kalamazoo, 49008 269 978-3500 teknalink.com

Terumo Cardiovascular Systems 6200 Jackson Road Ann Arbor, 48103 800 262-3304 terumo-cvs.com

Terumo Heart, Inc. 6180 Jackson Road Ann Arbor, 48103 734 741-6114 terumoheart.com

The Tech Group 3116 N. Wilson Ct. NW Walker, 49534 616 643-6001 techgroup.com

Thompson Surgical Instruments 10170 E Cherry Bend Rd Traverse City, 49684 231 922-0177 thompsonsurgical.com

Tissue Regenerating Systems 401 West Morgan Ann Arbor, 48108 N/A N/A

Topspins, Inc. 403 Riverview Dr. Ann Arbor, 48104 734 623-6400 topspins.com

TouchStone Innovations 1039 Olivia Ave. Ann Arbor, 48104 734 476-8502 N/A

Troy Biologicals, Inc. 1238 Rankin St Troy, 48083 800 521-0445 troybio.com

Twin Bay Medical, Inc. 11590 S. US-31 Williamsburg, 49690 231 264-0101 twinbaymedical.com

Ultralight Prosthetics, Inc. 24781 Five Mile Road Redford, 48239 313 538-8500 ultralightprosthetics.com

Ultrasound Medical Devices, Inc. 3917 Research Park, Suite B-7 Ann Arbor, 48108 734 369-5056 N/A

Versus Technology, Inc. 2600 Miller Creek Drive Traverse City, 49684 231 946-5868 versustech.com

Vigor Therapy Solutions 4915 Advance Way Stevensville, 49127 269 429-0191 vigorequipment.com

Waters 2805 S. Industrial Ann Arbor, 48104 734 761-9600 waters.com

Wizard Med LLC 48223 Chesterfield Canton, 48187 734 536-1602 wizardmed.com

Wright & Filippis, Inc. 2845 Crooks Rd. Rochester Hills, 48309 248 853-1888 firsttoserve.com

Xoran Technologies, Inc. 5210 South State Road Ann Arbor, 48108 734 663-7194 xorantech.com







59

RESEARCH & DEVELOPMENTAbsolute Laboratories Inc. 240 W. Auburn Rd. Rochester Hills, 48307 877 343-5227 absolutelabs.net

ADMETRx 4717 Campus Dr. Kalamazoo, 49008 269 372-3272 admetrx.com

Ann Arbor Clinical Research 203 South Zeeb Rd., Ste. 105 Ann Arbor, 48103 734 926-0957 annarborclinicalresearch.com

Antel BioSystems, Inc. 3655 Forest Rd. Lansing, 48910 800 631-3510 antelbio.com

ApoLife, Inc. 100 River Pl., #6850 Detroit, 48207 313 446-2625 apolife.com

Aptuit Consulting, Inc 91 Hartwell Ave. Lexington, MA, 02421 617 538-5688 aptuitconsulting.com

Arbor Preclinical & Consulting, LLC 8975 S. Ave E Scotts, 49088 734 330-4396 arborpcc.com

Arbor Research Collaborative for Health 315 W. Huron St., Ste. 360 Ann Arbor, 48103 734 665-4108 arborresearch.org

Arbor-Biotech LLC N/A Ann Arbor 734 622-1910 N/A

ASC Inc. 1945 Pauline Blvd. Ann Arbor, 48103 734 480-2952 asc-inc.net

ASI Instruments, Inc. 12900 E. 10 Mile Rd. Warren, 48089 586 756-1222 asi-instruments.com

Assay Designs, Inc. 5777 Hines Dr. Ann Arbor, 48108 734 668-6113 assaydesigns.com

Asterand plc TechOne Building, 440 Burroughs, Ste. 501 Detroit, 48202 313 263-0960 asterand.com

AzoRx, Inc. 526 Jasper St. Kalamazoo, 49007 269 585-5953 azorx.com

Beaumont Commercialization Center 3601 West 13 Mile Rd. Royal Oak, 48073 248 551-2667 beaumontcommercializationcenter.com

Bio-Chem Laboratories, Inc. 1049 28th St., SE Grand Rapids, 49508 616 248-4900 bio-chem.com/Home/tabid/36/Default.aspx

Biodiscovery, LLC 5692 Plymouth Rd. Ann Arbor, 48105 734 998-0751 Mycroarray.com

BioPharma Data Services 1461 Scio Ridge Ct Ann Arbor, 48103 734 255-1038 BioPharmaDataServices.com

BioSTAT Consultants, Inc. 528 West Centre Ave. Portage, 49024 269 329-7976 biostat.net/


CeeTox, Inc. 4717 Campus Dr., Ste. 500 Kalamazoo, 49008 269 353-5555 ceetox.com

Cell Culture Characterization Services 1872 North Adams Rochester Hills, 48306 248 656-2542 cellcharacterization.com

Charles River 9801 Shaver Rd. Portage, 49002 269 327-4248 criver.com

ClinSite, Inc. 24 Frank Lloyd Wright Dr., Lobby A Ann Arbor, 48106 734 930-3700 clinsite.com

ClinXus Cook-DeVos Center for Health Sciences Grand Rapids, 49503 616 331-5854 clinxus.org 301 Michigan St. NE, Ste. 520

CNVGenes LLC 4995 Arrowhead Rd. West Bloomfield, 48323 248 682-3368 cnvgenes.com


Covance Research Products 6321 South 6th St. Kalamazoo, 49009 269 375-0482 crpinc.com

Crissman Toxicologic Pathology, LLC 2887 Oakhaven Ct. Midland, 48642 989 631-2790 N/A

Cutting Image Histology, LLC 800 Technology Dr. Ann Arbor, 48108 734 945-9077 cuttingimagehistology.com

DBA Analytical (an NSF International Co.) 789 Dixboro Rd. Ann Arbor, 48113 734 769 8010 dba- global.com

Detroit R & D, Inc. Metropolitan Center for High Technology Detroit, 48201 313 961-1606 detroitrandd.com 2727 Second Ave, Ste. 4113

DNA Software, Inc. 334 East Washington St. Ann Arbor, 48104 734 222-9080 dnasoftware.com

Emil’s Molecular Design, LLC 8772 Trillium Dr Ypsilanti, 48197 N/A N/A

Essen Instruments 1156 Oak Valley Dr. Ann Arbor, 48108 734 769-1600 essen-instruments.com

Eurofins Avtech Laboratories, Inc. 6859 Quality Way Kalamazoo, 49002 269 323-3366 avtechlabs.com

Exponent, Inc. 39100 Country Club Dr. Farmington Hills, 48331 248 324-9135 exponent.com

Ferndale Pharma Group 780 West 8 Mile Rd. Ferndale, 48220 248 548-0900 ferndalelabs.com

Genemarkers LLC 4280 Commercial Ave., Ste. A. Portage, 49002 269 998-8116 genemarkersllc.com

Giri Diagnostics LLC 2611 Parmenter Blvd. Royal Oak, 48073 248 435-4472 giridiagnostics.com

Global Clinical Connections MTEC at the Groves at KVCC Kalamazoo, 49009 269 488-3277 globalclinicalconnections.com 7107 Elm Valley Dr., Ste. 2680

Global Remediation Technologies Inc. 1102 Cass St. Traverse City, 49684 800 899-3703 grtusa.com

Global Strategic Connections, LLC 2125 Butterfield Dr., Ste. 218 Troy, 48084 248 816-6881 gsc-llc.com

Grand River Aseptic Pharmaceutical Packaging, Inc. PO Box 3696 Grand Rapids, 49501 616 331-6980 GranDr.rAPP.com

Great Lakes Drug Development, Inc. 1032 Karl Greimel Dr., Ste. 11 Brighton, 48116 810 224-7500 gldrugdev.com

Housey Pharmaceutical Research Laboratories, LLC 16800 W 12 Mile Rd., Ste. 201 Southfield, 48076 248 663-7000 housey.com

i3 STATPROBE, Inc. 300 W. Morgan Rd. Ann Arbor, 48108 734 769-5000 i3statprobe.com

Inland Waters Pollution Control 2021 South Schaefer Hwy. Detroit, 48217 800 992-9118 inlandwaters.com

Innovative Research Inc. 46430 Peary Ct. Novi, 48377 248 896-0145 innov-research.com

Integrated Nonclinical Development Solutions, Inc. (INDS) 3005 Miller Ave. Ann Arbor, 48103 734 929-5392 INDS-Inc.com

International Discovery Sourcing Consultants LLC 300 N. Main St., Ste. 202 Chelsea, 48118 734 433-9670 idscbiotechnetwork.com

Intervention Insights 710 Kenmoor, Ste. 120 Grand Rapids, 49546 616 949-7500 interventioninsights.com

Jasper Clinical Research & Development, Inc. 526 Jasper St. Kalamazoo, 49007 269 276-8899 jasperclinic.com

JB Laboratories 13295 Reflections Dr. Holland, 49424 616 738-8500 jblabs.com






60


RESEARCH & DEVELOPMENT CONTINUEDJV Biolabs 2245 S. State St. Ann Arbor, 48104 734 395-8891 jvbiolabs.com

Kalexsyn, Inc. 4502 Campus Dr. Kalamazoo, 49008 269 488-8488 kalexsyn.com

KAR Bioanalytical, Inc. 4425 Manchester Rd. Kalamazoo, 49001 269 381-9666 karbio.com

Kendle International 315 E. Eisenhower Pkwy, Ste. 214 Ann Arbor, 48108 734 274-8500 kendle.com

Keystone Solutions Group 5121 East ML Ave., Ste. B-10 Kalamazoo, 49048 269 343-4108 keystone-pd.com

Lead Biopharma Consulting, LLC 7726 Brass Creek Ct. Dexter, 48130 734 418-2296 leadbiopharma.com

LexaMed, Ltd. 705 Front St. Toledo, OH 43605 419 693-5307 lexamed.net

Maximax Pharmaceutical Research 35560 Grand River, Ste.# 292 Farmington Hills, 48335 800 374-5270 maximax.com

MBI International 3900 Collins Rd. Lansing, 48910 517 337-3181 mbi.org

McClinchey Histology Lab, Inc P.O. Box 421, 100 Rice St. Stockbridge, 49285 517 851-9149 mhistolab.com

Merit Laboratories, Inc. 2680 E. Lansing Dr. East Lansing, 48823 517 332-0167 meritlabs.com

Michigan Animal Model Consortium 333 Bostwick Ave. Grand Rapids, 49503 616 234-5684 ctaalliance.org/cta-cores/michigan- animal-model-consortium

Michigan Antibody Technology Center - Center of 333 Bostwick Ave. Grand Rapids, 49503 616 234-5342 ctaalliance.org/cta-cores/michigan- Technology Excellence antibody-technologies-core

Michigan Biological Imaging Center Dept. of Biological Sciences, 3425 Woodhall, WMU Kalamazoo, 49008 269 387-5640 wmich.edu/bios/facilities/imaging-center

Michigan Center for Biological Information 3600 Green Ct., Ste. 700 Ann Arbor, 48105 ctaalliance.org/MCBI

Michigan Center for Structural Biology, MSU Dept. of Biochemistry, 310 A Biochemistry East Lansing, 48824 517 355-0199 mcsb.bch.msu.edu

Michigan Critical Care Consultants, (MC3) Inc. 3550 W. Liberty, Ste. 3 Ann Arbor, 48103 734 995-9089 mc3corp.com

Michigan Diagnostics LLC 2611 Parmenter Blvd. Royal Oak, 48073 248 435-4472 michdiag.com

Michigan High Throughput Screening Center - Kalamazoo Valley Community College Kalamazoo, 49009 269 353-1582 mhtsc.kvcc.edu Center of Technology Excellence 7170 Elm Valley Dr.

Michigan Proteome Consortium 300 North Ingalls Bldg., 11th Fl., Rm. 1198 Ann Arbor, 48109 734 763-3130 proteomeconsortium.org

Michigan Technology and Research Institute, LLC 2245 South State St., Ste. 1100 Ann Arbor, 48104 734 222-0013 MTRInstitute.com

Micro Machine Company 2429 North Burdick St. Kalamazoo, 49007 269 388-2440 micromachineco.com

Microbiological Associates, Inc. 37428 Hills Tech Dr. Farmington Hills, 48331 248 324-4800 microbioassociates.com

Micromyx, LLC 4717 Campus Dr. Kalamazoo, 49008 269 372-3758 micromyx.com

Milad Pharmaceutical Consulting 46701 Commerce Center Dr, Ste. D Plymouth, 48170 734 664-0394 miladpharmaconsulting.com

MIR Preclinical Services (Molecular Imaging Research) 800 Technology Dr. Ann Arbor, 48108 734 821-1063 molecularimaging.com

MitoStem 440 Burroughs Detroit, 48202 313 483-0385 N/A

MMS Holdings, Inc. 6880 Commerce Blvd. Canton, 48187 734 245-0310 mmsholdings.com

Molecular Innovations Inc. 46430 Peary Ct. Novi, 48377 888 557-5055 mol-innov.com

MPI Research 54943 North Main St. Mattawan, 49071 269 668-3336 mpiresearch.com

NextGen Sciences, Inc. 4401 Varsity Dr., Ste. E Ann Arbor, 48108 734 973-7914 nextgensciences.com

Northern Biomedical Research, Inc. 930 W. Sherman Blvd. Muskegon, 49441 231 759-2333 N/A

Oakland Genetics LLC 2925 Bond Rochester Hills ,48309 248 257-0000 oaklandgenetics.com

Ophthigenics LLC 2900 Huron Pkwy. Ste. 4 Ann Arbor, 48105 734 945-5408 ophthigenics.com

Ophthy-DS, Inc. 54943 N. Main St. Mattawan, 49071 269 250-2177 Ophthy-DS.com

Orchid Unique Orthopedic Solutions 6688 Dixie Hwy. Bridgeport, 48772 989 746-0780 orchid-orthopedics.com/unique

Originus, Inc. 3985 Research Park Dr., Ste. 200 Ann Arbor, 48108 734 913-8791 originusinc.com

Oxford Biomedical Research, Inc. 2165 Avon Industrial Dr. Rochester Hills, 48309 248 852-8815 oxfordbiomed.com

Paragon Laboratories, Inc. 12649 Richfield Ct. Livonia, 48150 734 462-3900 paragonlaboratories.com

Pathology Experts, LLC 2887 Oakhaven Ct. Midland, 48642 989 631-2790 pathexperts.com

Penn Pharmaceutical Services 10230 W. 50 N Columbus, IN 48201 812 342-3528 pennpharm.com

PharmOptima, LLC 6710 Quality Way Portage, 49002 269 329-4370 pharmoptima.com

Phillips Plastics Corp. 5706 Stonington Ct. West Bloomfield, 48322 248 851-8300 phillipsplastics.com

PhycoTech 620 BRd. St., Ste. 100 St. Joseph, 49085 616 983-3654 phycotech.com

Proteos, Inc. 4717 Campus Dr. Kalamazoo, 49008 269 372-3423 proteos.net

Quantum Laboratories 28221 Beck Rd., Ste. A-11 Wixom, 48393 248 348-7029 quantumlaboratories.com

Quest Research Institute 31000 Telegraph, Ste. 230 Bingham Farms, 48025 248 644-7770 questri.com

Regional Medical Lab, Inc 175 College St. Battle Creek, 49037 269 969-6161 rml-lab.com

RTI Health Solutions 3005 Boardwalk St., Ste. 105 Ann Arbor, 48108 734 213-5372 rtihs.org

RTI Laboratories, Inc. 31628 Glendale St. Livonia, 48150 734 422-8000 rtilab.com

Rubicon Genomics, Inc. 4355 Varsity Dr., Ste. E Ann Arbor, 48108 734 677-6210 rubicongenomics.com

S & J Laboratories 4669 Executive Dr. Portage, 49002 269 324-7383 sandjlab.com

SciTech Development 281 Kercheval Grosse Pointe Farms, 48236 313 576-8263 scitechdevelopment.com

Secretory IgA Inc. 803 N. Main St. Ann Arbor, 48104 734 994-0966 secretoryiga.com







61

RESEARCH & DEVELOPMENT CONTINUEDSequenom Center for Molecular Medicine 301 Michigan St. NE, Ste. 580 Grand Rapids, 49503 616 391-4330 cmmdx.org

Shrader Analytical and Consulting Laboratories, Inc. 440 Burroughs, Ste. 340 Detroit, 48202 313 894-4440 shraderlabs.com

SoloHill Engineering, Inc. 4370 Varsity Dr., Ste. B Ann Arbor, 48108 734 973-2956 solohill.com

Technology Partnership 8030 Coventry Grosse Ile, 48138 313 675-8295 N/A

Therapeutics Systems Research Laboratories, Inc. 540 Avis Dr., Ste. A Ann Arbor, 48108 734 663-4233 tsrlinc.com

Tolera Therapeutics, Inc. 350 E. Michigan Ave., Ste. 205 Kalamazoo, 49007 269 585-2100 tolera.com

TouchStone Innovations 1039 Olivia Ave. Ann Arbor, 48104 734 476-8502 N/A

Toxicogenomic Informatics and Solutions, LLC P.O. Box 27482 Lansing, 48909 N/A txisllc.com

TransPharm Preclinical Solutions, LLC 7190 Brooklyn Rd. Jackson, 49201 517 536-8210 transpharmsite.com

Troy Polymers 330 E. Maple, Ste. L Troy, 48083 248 733-1030 troypolymers.com

United BioSource Corp. 2200 Commonwealth Blvd., Ste. 100 Ann Arbor, 48105 734 994-8940 unitedbiosource.com

Velesco Pharmaceutical Services 46701 N. Commerce Center Dr. Plymouth, 48170 734 545-0696 velescopharma.com

VetGen, LLC 3728 Plaza Dr., Ste. 1 Ann Arbor, 48108 734 669-8440 vetgen.com

Warde Medical Laboratory 300 W. Textile Rd. Ann Arbor, 48108 734 214-0300 wardelab.com

Wayne State University Applied Genomics Technologies WSU-5197, Biological Science Bldg., Detroit, 48202 313 577-3555 bioinformatics.wayne.edu/MCGT 5047 Gullen Mall

West Michigan Regional Laboratory 1726 Knollcrest Circle SE Grand Rapids, 49546 616 526-8440 calvin.edu/admin/wmrl/


PHARMACEUTICALS 21st Century Therapeutics, Inc. 52673 Seven Oaks, Ste. 105 Shelby Township, 48108 734 945-8131 3d-biomatrix.com

AAPharmaSyn LLC 3985 Research Park Dr. Ann Arbor, 48108 734 213-2123 aapharmasyn.com

Aastrom Biosciences, Inc. 24 Frank Lloyd Wright Dr., Lobby K Ann Arbor, 48105 734 930-5555 aastrom.com

Abbott Nutrition 901 North Centerville Rd. Sturgis, 49091 269 651-0787 abbott.com

Access Business Group 7575 Fulton St. East Ada, 49335 616 787-6767 accessbusinessgroup.com

Adeona Pharmaceuticals 3930 Varsity Dr. Ann Arbor, 48108 734 332-7800 adeonapharma.com

ADMETRx 4717 Campus Dr. Kalamazoo, 49008 269 372-3272 admetrx.com

AFID Therapeutics Inc. 3900 Collins Rd., Ste. 1029 Lansing, 48910 517 336-4641 afidtherapeutics.com

Albemarle Corp. 1421 S. Kalamazoo St. South Haven, 49090 269 637-8474 albemarle.com

Alluvium Biosciences 789 N. Dixboro Rd. Ann Arbor, 48105 734 276-4921 N/A

AlphaCore Pharma 333 Parkland Plaza, Ste. 5 Ann Arbor, 48103 734 527-9137 N/A

Amgen 9935 N. Valley Hill Dr. Mequon, WI, 53092 262 240-9961 amgen.com

Aptuit Consulting, Inc 91 Hartwell Ave Lexington, MA, 02421 617 538-5688 aptuitconsulting.com

Arbor Assay 1514 Eisenhower Pl. Ann Arbor, 48108 734 677-1774 ArborAssays.com

Armune Biosciences, Inc. 350 East Michigan Ave., Ste. 500 Kalamazoo, 49007 269 349-8870 armune.com

Ash Stevens 5861 John C. Lodge Fwy. Detroit, 48202 313 872-6400 ashstevens.com

Assay Designs, Inc. 5777 Hines Dr. Ann Arbor, 48108 734 668-6113 assaydesigns.com

Asterand plc TechOne Building, 440 Burroughs, Ste. 501 Detroit, 48202 313 263-0960 asterand.com

Auburn Pharmaceutical Co. 1775 John R Rd. Troy, 48083 248 526-3700 auburnpharm.com

AureoGen Biosciences, Inc. 6475 Technology Ave., Ste. C Kalamazoo, 49009 269 353-3805 aureogen.com

Aursos, Inc. 350 East Michigan Ave, Ste. 500 Kalamazoo, 49007 269 381-4408 aursos.com

Bauer BioMedical, LLC 2625 Denison Dr. Mt. Pleasant, 48854 810 397-2882 N/A

Bayer Health Care 6549 Braemer Ave. Noblesville, IN, 46069 317 774-8069 bayerhealth.com

BD Diagnostics (formerly HandyLab Inc.) 5230 S. State Rd. Ann Arbor, 48108 734 663-4719 handylab.com

Becton Dickinson - Difco Laboratories 920 Henry St. Detroit, 48201 313 442-8000 bd.com

Berry & Associates, Inc. 2434 Bishop Circle E. Dexter, 48130 734 426-3787 berryassoc.com

Biodiscovery, LLC 5692 Plymouth Rd. Ann Arbor, 48105 734 998-0751 Mycroarray.com

Biomedical Diagnostics, LLC 5692 Plymouth Rd., Ste. B Ann Arbor, 48105 734 913-9040 bio-diagnostics.com

Biomide 21 Kercheval Ave., Ste. 330 Grosse Pointe Farms, 48236 313 886-0589 N/A

Biopelle 780 W. 8 Mile Rd. Ferndale, 48220 866 424-6735 biopelle.com

Biopolymer Innovations 16647 Chandler Rd. East Lansing, 48823 517 432-3044 biopolymerinnovations.com

Biosol, Ltd. 206 Fifth Ave. Ann Arbor, 48104 734 994-5300 liposol.com

BoroPharm, Inc. 39555 Orchard Hill Pl., Ste. 600 Novi, 48375 888 366-1496 boropharm.com


Cancer Stem Cell Genomics 1385 Burgundy Ann Arbor, 48105 734 995-0016 N/A

Caraco Pharmaceutical Laboratories, Ltd. 1150 Elijah McCoy Dr. Detroit, 48202 313 871-8400 caraco.com

Cayman Chemical Company 1180 E. Ellsworth Rd. Ann Arbor, 48108 734 971-3335 caymanchem.com






62


PHARMACEUTICALS CONTINUED Cerenis Therapeutics Inc. 900 Victors Way, Ste. 280 Ann Arbor, 48108 734 769-1110 cerenis.com

Cerise Nutraceuticals, Inc. 1670 Barlow St., Ste. A Traverse City, 49686 231 933-3300 cherrylotion.com

CNVGenes LLC 4995 Arrowhead Rd. West Bloomfield, 48323 248 682-3368 cnvgenes.com

Copagen 5528 Gallery Park Dr. Ann Arbor, 48103 734 904-0365 N/A

Corium International, Inc. 4558 50th St. Grand Rapids, 49512 616 656-4563 coriumintl.com

Detroit R & D, Inc. Metropolitan Center for High Technology, Detroit, 48201 313 961-1606 detroitrandd.com 2727 Second Ave, Ste. 4113

DSC Labs 1979 Latimer Dr. Muskegon, 49442 231 777-3012 dsclab.com

Ecology Health Products, Inc. 12941 E. Townline Rd. Goetzville, 49736 906 297-8770 ecologyproducts.com

Eisai, Inc. 100 Tice Blvd. Woodcliff Lake, NJ 07677 201 692-1100 eisai.com

Eloquest Healthcare 780 West 8 Mile Rd. Ferndale, 48220 877 433-7626 eloquesthealthcare.com

Emergent BioSolutions 3500 Martin Luther King Jr. Blvd. Lansing, 48906 517 327-1500 ebsi.com

Emiliem 4717 Campus Dr., Ste. 700 Kalamazoo, 49009 415 421-0222 emiliem.com

Esperion Therapeutics, Inc. 46701 Commerce Center Dr., Ste. B Plymouth, 48170 734 862-4840 esperion.com

exCel Cosmeceuticals, Inc. 4120 Maple Rd., Ste. 201 Bloomfield Hills, 48301 248 539-1212 xlafa.com

EXT Lifesciences, Inc. 2000 Town Center, Ste. 2370 Southfield, 48075 248 948-6910 extlifesciences.com

Ferndale Laboratories Inc. 780 West 8 Mile Rd. Ferndale, 48220 248 548-2422 ferndalelabs.com

Ferndale Pharma Group 780 West 8 Mile Rd. Ferndale, 48220 248 548-0900 ferndalelabs.com

Genentech 333 W. North Ave. Ste 399 Chicago, IL 60610 650 225-1000 gene.com

Genetics Squared, Inc. 401 West Morgan Rd. Ann Arbor, 48108 734 929-9475 genetics2.com

Giri Diagnostics LLC 2611 Parmenter Blvd. Royal Oak, 48073 248 435-4472 giridiagnostics.com

GlaxoSmithKline 7890 Charlie Ct. Lewis Center, OH, 43035 740 549-2426 gsk.com

Global Strategic Connections, LLC 2125 Butterfield Dr., Ste. 218 Troy, 48084 248 816-6881 gsc-llc.com

GlyTag LLC 32375 Lahser Rd. Beverly Hills, 48025 313 577-9827 glytag.com

Graminex, LLC 95 Midland Rd. Saginaw, 48638 877 472-6469 graminex.com

Grand River Aseptic Pharmaceutical Packaging, Inc. PO Box 3696 Grand Rapids, 49501 616 331-6980 GranDr.rAPP.com

Harvard Drug Company 31778 Enterprise Dr. Livonia, 48150 734 525-8700 harvarddrugs.com

HoMedics 3000 North Pontiac Trail Commerce Twp, 48390 248 863-3000 homedics.com

Horseshoe Herbals 1219 Anderson Rd. Niles, 49120 269 684-6888 horseshoeherbals.com

Housey Pharmaceutical Research Laboratories, LLC 16800 W 12 Mile Rd., Ste. 201 Southfield, 48076 248 663-7000 housey.com

Idea Sphere, Inc. 3133 Orchard Vista Dr SE Grand Rapids, 49546 616 464-5000 ideasphereinc.com

Innova Therapeutics 800 Technology Dr. Ann Arbor, 48108 734 222-9900 N/A

Innovative BioTherapies, Inc. 401 W. Morgan Rd. Ann Arbor, 48108 734 213-8350 innbio.com

Innovative Research Inc. 46430 Peary Ct. Novi, 48377 248 896-0145 innov-research.com

International Diagnostics Systems Corp. 2620 S. Cleveland Ave., Ste. 100, PO Box 799 St. Joseph, 49085 269 428-8400 ids-kits.com

JB Laboratories 13295 Reflections Dr. Holland, 49424 616 738-8500 jblabs.com

JHP Pharmaceuticals 870 Parkedale Rd. Rochester, 48307 248 656-5223 kingpharm.com

Jiva Pharma, Inc. 3995 Holden Dr. Ann Arbor, 48103 734 262-0673 N/A


Kalexsyn, Inc. 4502 Campus Dr. Kalamazoo, 49008 269 488-8488 kalexsyn.com

Komgen 3005 Whisperwood Dr., #288 Ann Arbor, 48105 734 272-5885 N/A

Lumigen, Inc. 22900 W. Eight Mile Rd. Southfield, 48033 248 351-5600 lumigen.com

Luminos LLC 1514 Eisenhower Place Ann Arbor, 48108 734 677-1774 luminosassays.com

Lycera Corp. 46701 N. Commerce Center Dr., Ste. C Plymouth, 48170 734 233-3060 lycera.com

Major Pharmaceuticals 31778 Enterprise Dr. Livonia, 48150 734 427-2576 majorpharmaceuticals.com

McKesson Pharmacy Systems 30881 Schoolcraft Livonia, 48150 734 779-8800 mckesson.com

MedArray, Inc. 3915 Research Park Dr., Ste. A-4 Ann Arbor, 48108 734 769-1066 permselect.com

MedElute, Inc. 259 East Michigan Ave., Ste. 407 Kalamazoo, 49007 269 352-3760 N/A

Meditrina Pharmaceuticals, Inc. 300 North Fifth Ave., Ste. 150 Ann Arbor, 48104 734 926-0966 meditrinapharma.com


Metabolic Solutions Development Co. 3133 Orchard Vista Dr. SE Grand Rapids, 49546 616 464-5071 msdrx.com

Michigan Antibody Technology Center - Center 333 Bostwick Ave. Grand Rapids, 49503 616 234-5342 ctaalliance.org/cta-cores/michigan- of Technology Excellence antibody-technologies-core

Michigan Diagnostics LLC 2611 Parmenter Blvd. Royal Oak, 48073 248 435-4472 michdiag.comMichigan Technology and Research Institute, LLC 2245 South State St., Ste. 1100 Ann Arbor, 48104 734 222-0013 MTRInstitute.com

MitoStem 440 Burroughs Detroit, 48202 313 483-0385 N/AMolecular Innovations Inc. 46430 Peary Ct. Novi, 48377 888 557-5055 mol-innov.com







63

PHARMACEUTICALS CONTINUED MuciMed, Inc 259 East Michigan Ave., Ste. 409 Kalamazoo, 49007 906 842-3212 N/A

Mycol Balm Laboratories, Inc. 9595 Raucholz Rd. St. Charles, 48655 989 585-3357 mycolbalm.com

NanoBio Corp. 2311 Green Rd., Ste. A Ann Arbor, 48105 734 302-4000 nanobio.com

Nanoderm Therapeutics, Inc. 3081 N. Foxridge Ct. Ann Arbor, 48105 734 665-4105 N/A

NanoVir LLC 4717 Campus Dr., Ste. 1300 Kalamazoo, 49008 269 372-3261 nanovirpharm.com

Natural Therapeutics, LLC 401 W. Morgan Rd. Ann Arbor, 48108 734 302-3200 fungalnailrelief.com

Neocutis, Inc. 440 Burroughs Detroit, 48202 734 207-5104 neocutis.com

Neogen Corp. 620 Lesher Pl. Lansing, 48912 800 234-5333 neogen.com

NephRx Corp. 4717 Campus Dr., Ste. 100 Kalamazoo, 49008 317 979-2483 nephrx.com

Next Generation Therapeutics, Inc 46701 Commerce Center Dr., Ste. A-6 Plymouth, 48170 734 527-9139 nextgenerationtherapeutics.com

NextGen Sciences, Inc. 4401 Varsity Dr., Ste. E Ann Arbor, 48108 734 973-7914 nextgensciences.com

Nitrate Elimination Company, Inc. 334 Hecla St. Lake Linden, 49945 906 296-1000 nitrate.com

Northern Biomedical Research, Inc 930 W. Sherman Blvd. Muskegon, 49441 231 759-2333 N/A

Novartis Pharmaceuticals Corp. One Health Plaza East Hanover, NJ 07936 N/A novartis.com

Nymirum 117 N First St. Ann Arbor, 48105 734 604-9597 nymirum.com

OncoImmune, Inc. 2900 N. Huron Pkwy., Ste. 2 Ann Arbor, 48105 734 994-8454 oncoimmune.com

Originus, Inc. 3985 Research Park Dr., Ste. 200 Ann Arbor, 48108 734 913-8791 originusinc.com

OtoMedicine, Inc. 330 East Liberty St., Lower Level Ann Arbor, 48104 269 615-0668 otomedicine.com

Oxford Biomedical Research, Inc. 2165 Avon Industrial Dr. Rochester Hills, 48309 248 852-8815 oxfordbiomed.com

Painex Corp. 18295 James Couzens Hwy. Detroit, 48235 313 863-1200 ringmasternow.com

Penn Pharmaceutical Services 10230 W. 50 N Columbus, IN 48201 812 342-3528 pennpharm.com

Perrigo Co. 515 Eastern Ave. Allegan, 49010 269 673-8451 perrigo.com

Pfizer Inc. 7000 Portage Rd. Kalamazoo, 49001 269 833-4000 pfizer.com

PG Pharmaceuticals, Inc. 2246 N. Monroe St. Monroe, 48162 248 632-1666 pg-pharma.com

Phadia US 4169 Commercial Ave. Portage, 49002 800 346-4364 phadia.us

Phrixus Pharmaceuticals, Inc. 300 N. Fifth Ave.,Ste. 150 Ann Arbor, 48104 734 358-9015 phrixuspharmaceuticals.com

Pointe Scientific, Inc. 5449 Research Dr. Canton, 48188 800 445-9853 pointescientific.com

ProNAi Therapeutics, Inc. 4717 Campus Dr., Ste. 1100 Kalamazoo, 49008 269 372-3289 pronai.com

Proteos, Inc. 4717 Campus Dr. Kalamazoo, 49008 269 372-3423 proteos.net

Quality Care Products 7560 Lewis Ave. Temperance, 48182 734 847-3847 qcpmeds.com

QuatRx Pharmaceuticals 777 East Eisenhower Pkwy., Ste. 100 Ann Arbor, 48108 734 913-9900 quatrx.com

RealBio Technology, Inc. 4717 Campus Dr., Ste. 1500 Kalamazoo, 49008 269 544-1088 realbiotechnology.com

Rockwell Medical Technologies, Inc. 30142 Wixom Rd. Wixom, 48393 800 449-3353 rockwellmed.com

Rubicon Genomics, Inc. 4355 Varsity Dr., Ste. E Ann Arbor, 48108 734 677-6210 rubicongenomics.com

sanofi-aventis US 55 Corporate Dr. Bridgewater, NJ, 08807 636 273-5409 sanofi-aventis.us

ScarPrev Pharmaceuticals 917 Packard St. Ann Arbor, 48104 734 717-9263 N/A

SciTech Development 281 Kercheval Grosse Pointe Farms, 48236 313 576-8263 scitechdevelopment.com

Secretory IgA Inc. 803 N. Main St. Ann Arbor, 48104 734 994-0966 secretoryiga.com

Sequenom Center for Molecular Medicine 301 Michigan St. NE, Ste. 580 Grand Rapids, 49503 616 391-4330 cmmdx.org

SoloHill Engineering, Inc. 4370 Varsity Dr., Ste. B Ann Arbor, 48108 734 973-2956 solohill.com

SPI Pharma PO Box 226 Grand Haven, 49417 231 935-6900 spipharma.com

SSV Therapeutics, LLC 2245 South State St., Ste. 1100 Ann Arbor, 48104 734 262-0673 ssvtherapeutics.com

Sterling Diagnostics 36645 Metro Ct. Sterling Heights, 48312 586 979-2141 sterlingdiagnostics.com

SubTerra LLC P.O. Box 55, 104 Wilcox Rd. White Pine, 49971 906 885-5953 subterrallc.com

Surefill LLC 4560 Danvers Dr. SE Grand Rapids, 49512 616 532-1700 surefill.com

Systems Specialties 390 Enterprise Ct., Ste. 200 Bloomfield Hills, 48302 248 332-0099 sysspec.com

Takeda Pharmaceuticals North America, Inc. One Takeda Pkwy. Deerfield, IL, 60015 715 246-9930 tpna.com

TCH Pharmaceuticals, Inc. 300 N. Fifth Ave., Ste. 150 Ann Arbor, 48104 734 926-0966 N/A

Team Pharmaceutical Inc. 563 116th Ave. Martin, 49070 269 388-5708 N/A

Technology Partnership 8030 Coventry Grosse Ile, 48138 313 675-8295 N/A

Therapeutics Systems Research Laboratories, Inc. 540 Avis Dr., Ste. A Ann Arbor, 48108 734 663-4233 tsrlinc.com

Tolera Therapeutics, Inc. 350 E. Michigan Ave., Ste. 205 Kalamazoo, 49007 269 585-2100 tolera.com

Tower Laboratories Montague 8060 Whitbeck Rd. Montague, 49437 231 893-1472 towerlabs.com

Troy Biologicals, Inc. 1238 Rankin St. Troy, 48083 800 521-0445 troybio.com

Urobiologics 31628 Glendale Ave. Livonia, 48150 313 574-7500 urobiologics.com

Velcura Therapeutics, Inc. 4300 Varsity Dr., Ste. D Ann Arbor, 48108 734 973-1000 velcura.com






64


PHARMACEUTICALS CONTINUED Velesco Pharmaceutical Services 46701 N. Commerce Center Dr. Plymouth, 48170 734 545-0696 velescopharma.com

Vertellus Health and Specialty Products, LLC 215 North Centennial St. Zeeland, 49464 800 223-0453 vertellus.com

Vortech Pharmaceuticals 6851 Chase Rd. Dearborn, 48126 313 584-4088 vortechpharm.com

W.F. Valentine & Co. 7633 Quackenbush Reading, 49274 517 283-3143 horseshoes.com

WelchDry 4270 Sunnyside Dr. Holland, 49424 616 399-2711 welchdry.com


zuSyn 4717 Campus Dr., Ste. 100 Kalamazoo, 49008 312 997-2150 zusyn.com

TESTINGAccess Diagnostics, Inc. 5575 Conner Ave, Ste. 1G Detroit, 48213 313 921-2266 accessdiagnostics.net

Antel BioSystems, Inc. 3655 Forest Rd. Lansing, 48910 800 631-3510 antelbio.com

Biomedical Diagnostics, LLC 5692 Plymouth Rd., Ste. B Ann Arbor, 48105 734 913-9040 bio-diagnostics.com

Biotech Clinical Laboratories 24469 Indoplex Circle Farmington Hills, 48335 248 426-9800 biotechclinical.com

Biotronic Neural Monitoring Specialists 812 Avis Dr. Ann Arbor, 48108 866 856-4404 biotronic.com

Cutting Image Histology, LLC 800 Technology Dr. Ann Arbor, 48108 734 945-9077 cuttingimagehistology.com

DRAMgene 39 Blackburn SW Wyoming, 49509 616 828-2207 N/A

Forensic Fluids Laboratories Inc. 225 Parsons St. Kalamazoo, 49007 269 492-7700 Forensicfluids.com

INVIA Medical Imaging Solutions 3025 Boardwalk St., Ste. 200 Ann Arbor, 48108 734 205-1231 inviasolutions.com

Medical Imaging Resources, Inc. 120 Enterprise Dr. Ann Arbor, 48103 734 426-3003 mobileleasing.com

Michigan Ear Institute 30055 Northwestern Highway, Ste. 101 Farmington Hills, 48336 248 865-4444 michiganear.com

Michigan Technology and Research Institute, LLC 2245 South State St., Ste. 1100 Ann Arbor, 48104 734 222-0013 MTRInstitute.com

Microbiological Associates, Inc. 37428 Hills Tech Dr. Farmington Hills, 48331 248 324-4800 microbioassociates.com

MIR Preclinical Services (Molecular Imaging Research) 800 Technology Dr. Ann Arbor, 48108 734 821-1063 molecularimaging.com

Neogen Corp. 620 Lesher Place Lansing, 48912 800 234-5333 neogen.com

Oakland Genetics LLC 2925 Bond Rochester Hills, 48309 248 257-0000 oaklandgenetics.com

Ophthy-DS, Inc 54943 N. Main St. Mattawan, 49071 269 250-2177 Ophthy-DS.com

Paragon Laboratories, Inc. 12649 Richfield Ct. Livonia, 48150 734 462-3900 paragonlaboratories.com

Phadia US 4169 Commercial Ave. Portage, 49002 800 346-4364 phadia.us

Quantum Laboratories 28221 Beck Rd., Ste. A-11 Wixom, 48393 248 348-7029 quantumlaboratories.com

Quest Diagnostics Inc. 4444 Giddings Rd. Auburn Hills, 48326 248 373-9120 questdiagnostics.com

Regional Medical Lab, Inc. 175 College St Battle Creek, 49037 269 969-6161 rml-lab.com

Roche Biomedical Labs 32355 Capitol St. Livonia, 48150 734 525-0248 N/A

S & J Laboratories 4669 Executive Dr. Portage, 49002 269 324-7383 sandjlab.com

Sequenom Center for Molecular Medicine 301 Michigan St. NE, Ste. 580 Grand Rapids, 49503 616 391-4330 cmmdx.org

Thumb MRI Center, LLC 6320 Van Dyke Rd. Cass City, 48726 989 872-8070 thumbmri.com

Universal Imaging 1159 E. Michigan Ave. Ypsilanti, 48198 734 528-0657 uimedical.com

VetGen, LLC 3728 Plaza Drive, Ste. 1 Ann Arbor, 48108 734 669-8440 vetgen.com

Warde Medical Laboratory 300 W. Textile Rd. Ann Arbor, 48108 734 214-0300 wardelab.com

Western Slope Laboratory 1197 Rochester Road, Ste. K Troy, 48083 248 307-1168 westernslopelabs.com

Apjohn Group, LLC 350 E. Michigan Ave., Ste. 500 Kalamazoo, 49007 269 349-8999 apjohngroup.com

Arboretum Ventures Market Place Bldg., 303 Detroit St., Ste. 301 Ann Arbor, 48104 734 998-3688 arboretumvc.com

Automated Software Technology 1328 Ramblewood East Lansing, 48823 517 316-2138 autosofttech.net

Bank of Ann Arbor 125 S. Fifth Ave., PO Box 8009 Ann Arbor, 48104 734 662-1600 boaa.com

Beaumont Services Company LLC 3601 W. 13 Mile Rd. Royal Oak, 48073 248 551-3010 beaumontservices.com

Biotechnology Business Consultants & BBCetc. 803 N. Main St. Ann Arbor, 48104 734 930-9741 bioconsultants.com

Brown & Brown of Detroit 35735 Mound Rd. Sterling Heights, 48311 586 977-6300 bbdetroit.com

Butzel Long 350 S. Main St., Ste. 300 Ann Arbor, 48104 734 213-3435 butzel.com

Calibrate, Inc. 3600 Green Ct., Ste. 400 Ann Arbor, 48105 919 240-4089 pipetpeople.com

Capital Advisors Group 29 Crafts St., Ste. 270 Newton, MA, 02458 617 630-8100 capitaladvisors.com

Chubb Group of Insurance Co. 5440 Corporate Dr., Ste. 300, PO Box 7078 Troy, 48007 734 741-1850 chubb.com

Consumer Benefits Group LLC 8649 Bonaventure Brighton, 48116 810 231-1231 consumerbg.com

CVCT, Inc. 5005-4 N. Lincoln Ave. Chicago, IL, 60625 773 818-8210 cvct.biz

Detroit Technical Equipment Co. 55 E. Long Lake Rd., PMB #433 Troy, 48085 248 232-8894 detroit-tech.com

Doeren Mayhew 755 West Big Beaver, Ste. 2300 Troy, 48084 248 244-3005 doeren.com

PROFeSS IONAL SeRvICeS







65

Drug & Laboratory Disposal, Inc. 331 Broad St. Plainwell, 49080 269 685-9824 dld-inc.com

Dykema Gossett PLLC 400 Renaissance Center Detroit, 48243 313 568-6800 dykema.com

Elsevier 3675 Crestwood Pkwy. Duluth, GA, 30096 678 344-8219 elsevier.com

Ernst & Young LLP 171 Monroe Ave. NW, Ste. 1000 Grand Rapids, 49503 313 628-7100 ey.com

e-Zassi 1886 S. 14th St. Amelia Island, FL, 32034 904 261-6290 ezassi.com

Farnell Equipment Co. 2950 Todd Dr. Troy, 48084 248 643-8890 farnell-equipment.com

Fulcrum Pharma Developments, Inc. 900 Victors Way, Ste. 160 Ann Arbor, 48108 734 994-7394 fulcrumpharma.com

Fullscope, Inc. 1399 Rand Rd. Canton, 48187 734 667-1204 fullscope.com

GCPM 405 Edgemoor Ave. Kalamazoo, 49001 N/A gettsconsulting.com

Gifford, Krass, Sprinkle, Anderson & Citkowski, PC PO Box 7021 Troy, 48007 248 647-6000 patlaw.com

Grant Thornton LLP 27777 Franklin Rd, Ste. 800 Southfield, 48034 N/A gt.com

Great Lakes Angels, Inc. 568 Woodway Ct., Ste. 1 Bloomfield Hills, 48302 248 540-3758 glangels.org

Harness, Dickey & Pierce, P.L.C. 5445 Corporate Dr., Ste. 200 Troy, 48098 248 641-1600 hdp.com

Honigman Miller Schwartz and Cohn LLP 350 E. Michigan Ave., Ste. 300 Kalamazoo, 49007 269 337-7700 honigman.com

Hylant Group 24 Frank Lloyd Wright Dr., Ste. J4100 Ann Arbor, 48105 734 741-0044 hylant.com

Innovative Analytics 161 E Michigan, Haymarket 5th Kalamazoo, 49007 269 488-3200 ianalytis.biz

Intertek 4700 Broadmoor, Ste. 200 Kentwood, 49512 616 656-0601 intertek.com

Kestrel Consultants, Inc. 410 Rose Dr. Ann Arbor, 48103 734 576-3031 kestrelconsultants.com

Law Offices of Gary Kendra, PC 143 Cady Centre, #319 Northville, 48167 248 596-1879 kendralaw.com

Linde Gas 2100 Western Ct., Ste. 100 Lisle, IL, 60532 734 424-1327 lindeus.com

Mangosoft 29A Riverside St. Nashua, NH, 03062 888 886-2646 mangosoft.com

Marketwire 200 W. Adams St., Ste. 2725 Chicago, IL, 60606 312 261-4212 marketwire.com

Miller, Canfield, Paddock and Stone, PLC 840 W. Long Lake Rd., Ste 200 Troy, 48098 313 963-6420 millercanfield.com

Monitor Liability Mangers Inc. 2850 W. Golf Rd., Ste. 800 Rolling Meadows, IL, 60008 N/A monitorliability.com

Nature Publishing Group 5 Varick St., 9th Fl. New York, NY, 10013 212 726-9760 nature.com

Office Depot 800 Eisenhower Pkwy Ann Arbor, 48106 734 259-9281 officedepot.com

O’Mara Scientific 3025 Sangra Ave. Grandville, 49418 616 531-9500 omarascientific.com

Performance Validation LLC 5148 Lovers Ln., Ste. 200 Portage, 49024 269 373-9112 perfval.com

Pharmacision LLC 1947 Mistwood Ct. Canton, 48187 734 895-3670 pharmacision.com

PharmaMed Resources, LLC 790 Crosswind Ln. Lindenhurst, IL, 60046 269 303-0798 pharmamedresources.com

PharmMor Consulting, LLC PO Box 2570 Portage, 49081 269 327-2215 N/A

Plex Systems 1731 Harmon Rd. Auburn Hills, 48326 248 391-8000 plex.com

Praxis Bio Consulting, LLC 2720 Aspen Ridge Ann Arbor, 48103 734 585-5296 praxisbio.com

Price, Heneveld, Cooper, DeWitt & Litton 695 Kenmoor SE Grand Rapids, 49501 616 949-9610 priceheneveld.com

Product Center for Agriculture and Natural 80 Agriculture Hall East Lansing, 48824 517 432-1676 productcenter.msu.edu Resources, Michigan State University

ProPharma Group 8175 Creekside Dr. Portage, 49024 888 242-0559 propharmagroup.com

ProReg Resources, LLC 8889 2nd St. Mattawan, 49071 269 372-2911 proregresources.com

Quality Air Service, Inc. 6701 Quality Way Portage, 49002 269 327-3055 qairservice.com

Rader, Fishman & Grauer PLLC 39533 Woodward Ave., Ste. 140 Bloomfield Hills, 48304 248 594-0600 raderfishman.com

Safis Solutions LLC 342 Massachusetts Ave., Ste. 402 Indianapolis, IN, 46204 317 777-6200 safis-solutions.com

Science Direct 3675 Crestwood Pkwy., Ste. 400 Duluth, GA, 30096 770 935-6077 elsevier.com

Single Source Procurement, LLC 4717 Campus Dr. Kalamazoo, 49008 269 372-3997 sspusa.com

Skyline Property Group, Inc. 2146 Livernois Troy, 48083 248 680-9900 N/A

Smith Haughey Rice & Roegge 213 S. Ashley, Ste. 400 Ann Arbor, 48104 734 213-8000 shrr.com

Switchback 300 N. Fifth, Ste. 120 Ann Arbor, 48104 734 418-8348 switchbackcms.com

Tech Depot N/A N/A 313 263-0960 bio.techdepot.com

Teresa M. Arnold & Assoc. 8300 Adler Rd. Lambertville, 48144 734 854-1187 tmaapr.com

The Point Services 1515 Chimney Ridge Traverse City, 49686 231 366-4121 thepointservcies.com

The Project Group 7238 Windhaven Ct. Portage, 49024 269 321-0411 N/A

Trialon Corp. 5600 New King St., Ste. 345 Troy, 48098 248 641-1032 trialon.com

Trossen HR Group 58 Parkland Plaza, Suite 200 Ann Arbor, 48103 734 904-5611 trossenhr.com

Validation & Compliance Institute, LLC 1529 Boxford Rd. Dearborn, 48183 734 274-4680 vcillc.com

Varnum, Riddering, Schmidt & Howlett Bridgewater Pl, 333 Bridge St. NW Grand Rapids, 49501 616 336-6000 varnumlaw.com

VWR International 1668 Chapleau Dr. Ann Arbor, 48103 800 932-5000 vwr.com

Warner Norcross & Judd LLP 900 Fifth Third Center, 111 Lyon St NW Grand Rapids, 49503 616 752-2169 wnj.com

PROfESS IONAL SERvICES CONTINUED





66

GOveRNMeNT/NON-PROFIT

Arrow Electronics 44760 Helm St. Plymouth, 48170 937-428-7300 arrow.com

Divtech Equipment Co. PO Box. 58468 Cincinnati, OH 45258 513-941-0483 divtechequipment.com

Landaal Packaging Systems 3256 B. Iron St. Burton, 48529 810 223-0605 landaal.com

Midwest Cleanroom Associates, Inc. 2055 Oak Industrial Dr., Ste A Grand Rapids, 49505 616 458-8533 mcacleanrooms.com

PTI Engineered Plastics, Inc. 50900 Corporate Dr. Clinton Twp, 48044 586 263-5100 teampti.com

SMG Cleanroom Technologies 2685-G Northridge Dr. Grand Rapids, 49544 616-785-3330 smgcleanrooms.com/

Staubli Corporation 44467 Charnwood Dr. Plymouth, 48170 734 417-4970 staubli.us.com

American Society for Microbiology 8205 Huron River Dr. Dexter Twp., 48130 734 845-3661 mi-asm.org

American Society of Employers 23815 Northwestern Hwy. Southfield, 48075 248 355-4500 aseonline.org

American Diabetes Assoc. 30300 Telegraph Rd., Ste 117 Bingham Farms, 48025 248 433-3830 diabetes.org

Ann Arbor SPARK 201 S. Division, Ste. 430 Ann Arbor, 48104 734 761-9317 AnnArborUSA.org

Automation Alley 2675 Bellingham Troy, 48083 248 457-3200 automationalley.com

Biosciences Research & Commercialization Ctr. 4717 Parkview Campus Dr. Kalamazoo, 49008 269 544-1072 brcc.wmich.edu

City of Marshall Economic Development 323 W. Michigan Marshall, 49068 269 781-5183 cityofmarshall.com

Gift of Life Michigan 2203 Platt Rd. Ann Arbor, 48104 800 482-4881 giftoflifemichigan.org

GöteborgBio - BRG 3260 Homestead Ct. Saline, 48176 734 429-4961 goteborgbio.se

Great Lakes Entrepreneur’s Quest 3520 Green Ct. Ann Arbor, 48105 734 647-8951 gleq.org

Juvenile Diabetes Research Fdn. 24359 Northwestern Hwy., #225 Southfield, 48075 248 355-1133 jdrfdetroit.org

International Partnership for 828 W. Grand River Ave. Brighton, 48116 810 494-7193 cmod.org Critical Markers of Disease (CMOD)

Medical Main St.-Oakland County Planning 1200 Pontiac Lake Rd., Bldg 41W Waterford, 48328 248 858-9099 medicalmainst.org & Economic Development

Michigan Agri-Business Assoc. 1501 N. Shore Dr., Ste. A East Lansing, 48823 517 332-8663 miagbiz.org

Michigan Association of Health Plans 327 Seymour Ave. Lansing, 48933 517 371-3181 mahp.org

Michigan Chemistry Council 326 W. Ottawa, Capitol Corners Lansing, 48933 517 372-8898 michiganchemistry.com

Michigan Citizens for Stem Cell Research 27177 Lahser Rd., Ste. 102 Southfield, 48034 248 948-5555 stemcellresearchformichigan.com and Cures (MCSCRC)

Michigan Corn Growers Assoc./Corn Marketing 12800 Escanaba Dr., Ste. B Dewitt, 48820 517 323-6600 micorn.org Program of Michigan

Michigan Economic Development Corporation 300 North Washington Square Lansing, 48913 517 373-9808 michiganadvantage.org

Michigan Health & Hospital Assoc. 6215 W. St. Joseph Hwy. Lansing, 48917 517 323-3443 mha.org

Michigan Health Council 2410 Woodlake Dr., PO Box 30014 Okemos, 48864 517 347-3332 mhc.org

Michigan Israel Business Bridge 3520 Green Ct., Ste. 450 Ann Arbor, 48105 734 604-2479 michiganisrael.com

Michigan Life Science and Innovation Ctr. (MLSIC) 46701 Commerce Center Dr. Plymouth, 48170 N/A mlsic.com

Michigan Medical Dental Assoc. 325 W. Lake Lansing Rd., Ste. C East Lansing, 48823 517 332-8663 smilemichigan.com

Michigan Molecular Institute 1910 W. St. Andrews Rd. Midland, 48640 989 832-5550 mmi.org

Michigan Nurses Assoc. 2310 Jolly Oak Rd. Okemos, 48864 517 349-5818 minurses.org

Michigan Osteopathic Assoc. 2445 Woodlake Circle Okemos, 48864 517 347-1555 mi-osteopathic.org

Michigan Primary Care Assoc. 7215 Westshire Dr. Lansing, 48917 517 381-8000 mpca.net

Michigan Research Institute 401 W. Morgan Rd. Ann Arbor, 48108 734 302-3200

Michigan Science Teachers Assoc. 3300 Washtenaw Ave., Ste. 220 Ann Arbor, 48104 734 973-0433 msta-mich.org

Michigan Small Business & Technology Grand Valley State Univ., 510 W. Fulton St. Grand Rapids, 49504 616 331-7480 misbtdc.org Development Center

Michigan Soybean Promotion Committee 140 W. Tuscola St., PO Box 287 Frankenmuth, 48734 989 652-3294 michigansoybean.org

Michigan State Medical Society 120 W. Saginaw East Lansing, 48826 517 337-1651 msms.org

Michigan Venture Capital Assoc. 425 N. Main St. Ann Arbor, 48104 734 223-3750 michiganvca.org

MidMichigan Innovation Ctr. 4520 E. Ashman Rd., Ste. M Midland, 48642 989 839-2333 mmic.us

National Center for Manufacturing Sciences 3025 Boardwalk Ann Arbor, 48108 800 222-6267 ncms.org

National Kidney Foundation of Michigan 1169 Oak Valley Dr. Ann Arbor, 48108 734 222-9800 nkfm.org

PhRMA (Pharmaceutical Research and 950 F St., NW, Ste. 300 Washington, DC, 20004 202 835-3400 phrma.org Manufacturers of America)

Southwest Michigan First 241 East Michigan Ave. Kalamazoo, 49024 269 553-9588 southwestmichiganfirst.com

Southwest Michigan Innovation Center 4717 Campus Dr., Ste. 100 Kalamazoo, 49008 269 353-1823 kazoosmic.com

The Right Place, Inc. 161 Ottawa Ave. NW, Ste. 400 Grand Rapids, 49503 616 771-0325 rightplace.org

TechTown 440 Burroughs Detroit, 48202 313 879-5250 techtownwsu.org/

West Michigan Science and Technology Initiative 301 Michigan St. NE, Ste. 537 Grand Valley State Univ. Grand Rapids, 49503 616 331-5840 wmsti.org

MANUfACTURING SUPPLIERS







67

American Society of Employers 23815 Northwestern Hwy. Southfield, 48075 248 223-8019 aseonline.org

Beaumont Hospitals 3601 W. Thirteen Mile Rd. Royal Oak, 48073 248 551-8550 beaumonthospitals.com

Borgess Research Institute 1521 Gull Rd. Kalamazoo, 49048 269 226-5407 research.borgess.com

Field Neuroscience Institute 4677 Towne Centre Rd., Ste. 101 Saginaw, 48604 989 497-3117 fni.org

Grand Valley State University 301 Michigan St. NE, Cook-DeVos Center Grand Rapids, 49503 616 331-8643 gvsu.edu for Health Sciences, Ste. 554

Henry Ford Hospital 2799 W. Grand Blvd. Detroit, 48202 313 916-2024 henryford.com

Karmanos Cancer Institute 4100 John R. Detroit, 48201 313 576-8931 karmanos.org

Michigan Nanotechnology Institute 1150 W. Medical Center Dr., Ann Arbor, 48109 734 647-2777 nano.med.umich.edu for Medicine & Biological Sciences, U-M SPC 5648, 9220C MSRB III

Michigan State University Office of 120 W. Saginaw East Lansing, 48826 517 377-1651 vprgs.msu.edu Research & Graduate Studies

Michigan State University Institute for D 132 W. Fee Hall East Lansing, 48824 517 432-4325 ihcs.msu.edu HealthCare Studies

Michigan State University, MSU Technologies 301 Administration Bldg. East Lansing, 48824 517 355-5040 cga.msu.edu

Michigan Technological University Office of 1400 Townsend Dr.Advanced Technology Houghton, 49931 906 487-2228 mtu.edu Technology and Economic Development Development Complex

Michigan Universities Commercialization Initiative (MUCI) 3003 South State St., Wolverine Tower, Rm, 1006 Ann Arbor, 48109 734 647-5730 muci.org

Oakland Community College - Orchard Ridge Campus 27055 Orchard Lake Rd., C-101 Farmington Hills, 48334 248 522-3741 oaklandcc.edu/MolecularBiotechnology/

Oakland University 520 Dowd Hall Rochester, 48309 248 370-2100 oakland.edu

Robertson Research Institute 4215 Fashion Square Blvd. Saginaw, 48603 989 799-8720 robertsoninstitute.org

The MRI Institute for Biomedical Research Imaging 440 East Ferry St., Unit 2 Detroit, 48202 313 758-0065 mrimaging.com

U-M Biomedical Engineering 2200 Bonisteel Blvd. Ann Arbor, 48109 734 764-9588 bme.umich.edu

U-M Center for Oral Health 1011 North University, Rm. 3228 Ann Arbor, 48109 734 647-4622 dent.umich.edu/research/clinicalresearch

U-M Life Sciences Institute 210 Washtenaw Ave. Ann Arbor, 48109 734 763-1200 lsi.umich.edu

U-M Medical Innovation Ctr. 24 Frank Lloyd Wright Dr., Lobby M, Ste. 2600 Ann Arbor, 48106 734 998-6994 med.umich.edu/ummic

U-M Michigan Institute for Clinical Health Research 24 Frank Lloyd Wright Dr., Lobby M Ann Arbor, 48106 734 998-7474 michr.umich.edu

U-M Office of Vice President for Research 4080 Fleming Bldg., 503 Thompson Ann Arbor, 48109 734 764-1185 research.umich.edu

U-M Technology Transfer Office 1214 S. University Ann Arbor, 48104 734 763-0614 techtransfer.umich.edu

Van Andel Institute 333 Bostwick Ave. NE Grand Rapids, 49503 616 234-5000 vai.org

Wayne State University - Technology Commercialization 440 Burroughs, Ste. 201 Detroit, 48202 313 577-5541 techtransfer.wayne.edu

Western Michigan University 1903 W. Michigan Ave. Kalamazoo, 49008 269 387-1000 wmich.edu

EDUCATION/CLINICAL


The Pharmaceutical Research and Manufacturers of America

PhRMA MEMBER COMPANIES ARE COMMITTED TO SUPPORTING ECONOMIC GROWTH & FURTHER RESEARCH

THAT LEADS TO GOOD JOBS & THRIVING COMMUNITIES.

Save the Date6th Annual MichBio expo & ConferenceTuesday, October 26 & Wednesday, October 27, 2010Marriott at Eagle Crest, Ypsilanti

PLAN TO ATTeND THe PReMIeR BIOSCIeNCeS eveNT IN MICHIGAN CONFeReNCe HIGHLIGHTS • Concurrent session tracks in Pharma, Medical Device emerging Business, and Bio-based Technologies • CEO Dinner forum • Business partnering meetings • New technology and emerging company presentations • Exhibit Hall • facility tours and much more! Over 70% of attendees are biosciences executives

ExHIBITOR/SPONSOR INfORMATION & RESERvATIONSContact [email protected]

Reserve Your Ad Now! BioMatters will be published

October 25, 2010. CIRCULATION Print distribution to MichBio members and stakeholders, attendees at the MichBio expo and BIO International Convention and numerous other state and national events. Digital distribution to more than 7,000 addresses including biosciences companies and service providers, state and regional funding sources, economic development organiza-tions, universities and research institutions.

ADveRTISING RATeS MichBio Members (Non-members add 10%): Inside Front Cover $4,000 Back Cover 3,500 Inside Back Cover 3,000 Full page 2,000 Half page 1,000 Quarter page 500 Digital version only e-blast teaser 1,000 Page 0 5,000

INFORMATION/ReSeRvATIONSContact Jayne Berkaw 734.527.9147 [email protected]

IN MICHIGAN, SOMETHING NEW IN HIGH-TECH INNOVATION IS HAPPENING EVERY DAY.

Working with our partners at MichBio, the Michigan Economic Development CorporationSM can connect high-tech companies and entrepreneurs to services, incentives, networking opportunities and venture capital to help them grow and prosper.

Visit MichiganAdvantage.org and learn how Michigan can give your biotech company the Upper Hand.

MichiganAdvantage.org

Nurturing an idea into a market-able product and growing it into a dynamic, self-sustaining bioscience company is a process. How do Michigan companies connect with the right people, learn what they need to know, find the resources to keep the pipeline flowing?

Get Connected.

In a state boasting the world’s longest freshwater coastline, with oceans of lakes, where water is a way of life and life is good; in an industry that studies life at its core, MichBio is there to propel Michigan’s bioscience people, products and prospects.

Join us.

MichBio brings the total continuum together. We know the players, the market; and what it takes. We give you access to a valuable network of people representing all facets of the biosciences community. We are your matchmaker, your guru and your standard bearer.

Ann Arbor, MichigAn 734.527.9150 www.Michbio.org

biomatters - spring 2010

Documents

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university of michigan

michigans economy

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