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Author(s): Allen Flynn License: Unless otherwise noted, this material is made available under the terms of the Creative Commons Attribution- NonCommercial-ShareAlike 3.0 License: http://creativecommons.org/licenses/by-nc-sa/3.0/ We have reviewed this material in accordance with U.S. Copyright Law and have tried to maximize your ability to use, share, and adapt it. The citation key on the following slide provides information about how you may share and adapt this material. Copyright holders of content included in this material should contact [email protected] with any questions, corrections, or clarification regarding the use of content. For more information about how to cite these materials visit http://open.umich.edu/education/about/terms-of-use. Any medical information in this material is intended to inform and educate and is not a tool for self-diagnosis or a replacement for medical evaluation, advice, diagnosis or treatment by a healthcare professional. Please speak to your physician if you have questions about your medical condition. Viewer discretion is advised: Some medical content is graphic and may not be suitable for all viewers. 1

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Page 1: Author(s): Allen Flynn License: Unless otherwise noted, this material is made available under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike

Author(s): Allen Flynn

License: Unless otherwise noted, this material is made available under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License: http://creativecommons.org/licenses/by-nc-sa/3.0/

We have reviewed this material in accordance with U.S. Copyright Law and have tried to maximize your ability to use, share, and adapt it. The citation key on the following slide provides information about how you may share and adapt this material.

Copyright holders of content included in this material should contact [email protected] with any questions, corrections, or clarification regarding the use of content.

For more information about how to cite these materials visit http://open.umich.edu/education/about/terms-of-use.

Any medical information in this material is intended to inform and educate and is not a tool for self-diagnosis or a replacement for medical evaluation, advice, diagnosis or treatment by a healthcare professional. Please speak to your physician if you have questions about your medical condition.

Viewer discretion is advised: Some medical content is graphic and may not be suitable for all viewers.

Page 2: Author(s): Allen Flynn License: Unless otherwise noted, this material is made available under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike

Citation Keyfor more information see: http://open.umich.edu/wiki/CitationPolicy

Use + Share + Adapt

Make Your Own Assessment

Creative Commons – Attribution License

Creative Commons – Attribution Share Alike License

Creative Commons – Attribution Noncommercial License

Creative Commons – Attribution Noncommercial Share Alike License

GNU – Free Documentation License

Creative Commons – Zero Waiver

Public Domain – Ineligible: Works that are ineligible for copyright protection in the U.S. (17 USC § 102(b)) *laws in your jurisdiction may differ

Public Domain – Expired: Works that are no longer protected due to an expired copyright term.

Public Domain – Government: Works that are produced by the U.S. Government. (17 USC § 105)

Public Domain – Self Dedicated: Works that a copyright holder has dedicated to the public domain.

Fair Use: Use of works that is determined to be Fair consistent with the U.S. Copyright Act. (17 USC § 107) *laws in your jurisdiction may differ

Our determination DOES NOT mean that all uses of this 3rd-party content are Fair Uses and we DO NOT guarantee that your use of the content is Fair.

To use this content you should do your own independent analysis to determine whether or not your use will be Fair.

{ Content the copyright holder, author, or law permits you to use, share and adapt. }

{ Content Open.Michigan believes can be used, shared, and adapted because it is ineligible for copyright. }

{ Content Open.Michigan has used under a Fair Use determination. }

Page 3: Author(s): Allen Flynn License: Unless otherwise noted, this material is made available under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike

3

Key Elements & Functionsof Information Systems

Motivation lecture in Course –

Introduction to Health InformaticsFall 2013Allen Flynn, PharmD

Graduate Student Instructor

Page 4: Author(s): Allen Flynn License: Unless otherwise noted, this material is made available under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike

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Course Map-Week 6

5 DOMAINS 10 METHODS4 INFO.

RESOURCES

EHRs (VistA) Elements & functionsof Info. Systems HIT STANDARDS

time

i

iiSkill

Modules

Lectures DISCUSSION DAY

KICKOFF

END

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Upcoming Course Dates & Other News

• Last day Skill Module 1 full credit today• Next meeting after fall break, Wed. 10/16• New Tutors’ Schedule Posted on Ctools• Paper/Essay 1 due October 16th, 3pm~~~• Materials for Skill Module 2 now available• Open tutoring/testing October 23rd

• Last day Skill Module 2 = Oct 30th

Page 6: Author(s): Allen Flynn License: Unless otherwise noted, this material is made available under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike

6

Agenda for Today• On Computation• Types of Information Systems

– Communication systems– Database systems– Advice-giving systems

• Types of Knowledge• Data Modeling• Data Privacy & Security • Content & materials for Skill Module 2

Page 7: Author(s): Allen Flynn License: Unless otherwise noted, this material is made available under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike

7

Computation is…

noun “determining something by mathematical and/or logical methods”*

*Wordnet 3.0

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Computation is…

Numerical/ArithmeticalMathematical ( + − × ÷ ) interacting with

Qualitative / Logical Procedural

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Bounded rationality.

“The meaning of rationality in situations where the complexity of the environment is immensely greater than the computational powers of the adaptive system”, Simon, The Sciences of the Artificial, p. 166

INFORMATION

TIME

INDIVIDUAL KNOWLEDGE & CAPABILITY(Speed/Memo

ry)

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Human Limitations: Genomic Data and Decision Making

Decisions by clinical phenotype

i.e., traditional health care

1000

Fact

s pe

r Dec

isio

n

10

100

1990 2000 2010 2020

Human Cognitive Capacity

Functional Genetics:

Gene expression profiles

Slide courtesy of Bill Stead & Dan Masys

Proteomics and other

effector molecules

Structural Genetics:

e.g. SNPs, haplotypes

10

Page 11: Author(s): Allen Flynn License: Unless otherwise noted, this material is made available under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike

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Remember the Goal of Informatics

The “practice” of informatics is the pursuit of information and knowledge resources that seek to make people “better” than they would be if unassisted, and also to explore if they have been successful in that pursuit.

*Friedman CP. A ‘fundamental theorem’ of biomedical informatics. Journal of the American Medical Informatics Association, 16: 169-170, 2009.

( + >)

The “Fundamental Theorem”:*

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• On Computation• Types of Information Systems

– Communication systems– Database systems– Advice-giving systems

• Types of Knowledge• Data Modeling• Data Privacy & Security • Content & materials for Skill Module 2

Page 13: Author(s): Allen Flynn License: Unless otherwise noted, this material is made available under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike

Information Systems• A system is an organized set of parts and procedures

for accomplishing a task• A system is composed of elements (sub-systems)

that work together to accomplish a task not achievable by any of the elements alone

• Information systems include:– Hardware (physical parts; “nuts and bolts”)– Software (coded instructions: “bits and bytes”)– People – Socio-cultural context(s)

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Communication Systems

• Sender sends a message to a receiver• Communication is successful if the receiver

derives the same meaning and/or acts as the sender intended

• Complete communication usually includes a confirmation of receipt (send back from receiver to sender)

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MessagesImage removed - copyright

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15

Health Information Exchange is…

(a) Verb “The electronic sharing of health-related information among organizations.”

p. 17For a similar definition to (a) above of HIE see:Image removed - copyright

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Communication and Health Information Exchange

• The Challenge: Requires ‘micrometer precision’ in specifying syntax and semantics– Machines are “brittle” and unforgiving

• Syntax = The structure of the message |>>BEGINNING|What is Being Sent (a Finding)|Name of Finding|How Name Coded|Value|How Value Coded|END<<|• Semantics: The meanings of the codes

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Page 17: Author(s): Allen Flynn License: Unless otherwise noted, this material is made available under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike

Database Management Systems

• Data structured as: fields, records, and files• Transactions change the value of data elements

– Records of transactions are themselves a form of data

• Data management functions: enter, edit, browse, search, analyze, report

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Page 18: Author(s): Allen Flynn License: Unless otherwise noted, this material is made available under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike

Advice-Giving System Architecture

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Data Knowledge

Reasoner

Renderer

Human Decision-Maker

Trigger

Image Removed - Copyright

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What is Advice?

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advice, n, guidance or recommendations concerning prudent future action

from Google, Inc., 2013.

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Key Ingredients of Successful Advice-Giving

(a.k.a., Clinical Decision Support or CDS)

• Go after the right problem• Tell the user:

– something correct or at least plausible – that he/she doesn’t already know

(or cannot reasonably be expected to compute or recall)

• Conform to how:– the user thinks (thoughtflow)– the user works (workflow) 20

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Advice-Giving System Architecture

21

Data Knowledge

Reasoner

Renderer

Human Decision-Maker

Trigger

Image Removed - Copyright

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Selected Alternatives for Representing Knowledge

• Rules• Entities and relations among them

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Representation as Rules

IF:

An order for a FLUOROSCOPY is received AND

The patient’s serum BUN level > 20 mg/dL AND

The patient’s serum CREATININE level is > 2.5 mg/dL,

THEN:

Send a message to the patient's physician indicating a possible adverse effect of fluoroscopy.

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Representation as Entities & Relations

ontology, n, an exhaustive organization of some knowledge domain that contains all the relevant entities and their relations*

*Wordnet 3.0

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Entities & Relations

COURSES

Undergrad.Courses

GraduateCourses

RequiredCourses

STUDENTSINSTRUCTORS

Teach/AreTaught by

Take/AreAvailable to

Include/Are examples of

CompletedCourses

Have been credited tostudents

Get

cre

dit f

or

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Sets: Entities & Relations

Courses requiredfor your degree

Courses you havecompleted

Closedcourses

542721525501

618514515317

425632816

590591

6778xx9xx

Page 27: Author(s): Allen Flynn License: Unless otherwise noted, this material is made available under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike

Advice-Giving System Architecture

27

DataKnowledge

Reasoner

Renderer

Human Decision-Maker

Trigger

Image removed - copyright

Page 28: Author(s): Allen Flynn License: Unless otherwise noted, this material is made available under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike

The Reasoner

• The working of the reasoner depends on the knowledge representation model

• Rules: Logic operations that determine whether the rule “fires” or not

• Sets: Feed patient data to the model and infer a categorization or implication

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Page 29: Author(s): Allen Flynn License: Unless otherwise noted, this material is made available under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike

Can all knowledge berepresented to make

it computableby machines (IT)?

29

Page 30: Author(s): Allen Flynn License: Unless otherwise noted, this material is made available under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike

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• On Computation• Types of Information Systems

– Communication systems– Database systems– Advice-giving systems

• Types of Knowledge• Data Modeling• Data Privacy & Security • Content & materials for Skill Module 2

Page 31: Author(s): Allen Flynn License: Unless otherwise noted, this material is made available under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike

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Exhibit 8.1: Types of Knowledge

© 2012 Health Administration Press

The speed limit is 70 miles per hour

Drive slower in icy conditions

Skilled performances, e.g., evasive maneuver

Solve novel problem: flat tires + wet road

p. 155

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• On Computation• Types of Information Systems

– Communication systems– Database systems– Advice-giving systems

• Types of Knowledge• Data Modeling• Data Privacy & Security • Content & materials for Skill Module 2

Page 33: Author(s): Allen Flynn License: Unless otherwise noted, this material is made available under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike

Modeling

• A representation of a system that allows for investigation of the properties of the system and, in some cases, prediction of future outcomes.

• Models allow us to understand the dynamics of a system, and the consequences of changing a system without having to experiment on the system itself.

• Models are abstractions• Models are never complete

– A good model captures the key features

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Page 34: Author(s): Allen Flynn License: Unless otherwise noted, this material is made available under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike

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Exhibit 9.3: The Modeling Process

© 2012 Health Administration Press

Models are incompleterepresentations of the real world

p. 187

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Important Types of Models

• Data models > includes entity-relationship models

• Decision models• Information flow models

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Page 36: Author(s): Allen Flynn License: Unless otherwise noted, this material is made available under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike

Data Model – Common Cold

36

COMMON COLD

RECENTCONTACTS

SYMPTOMSINDIVIDUAL

REMEDIES

ONSETDURATION

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Information Flow Models

37

Page 38: Author(s): Allen Flynn License: Unless otherwise noted, this material is made available under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike

38

• On Computation• Types of Information Systems

– Communication systems– Database systems– Advice-giving systems

• Types of Knowledge• Data Modeling• Data Privacy & Security • Content & materials for Skill Module 2

Page 39: Author(s): Allen Flynn License: Unless otherwise noted, this material is made available under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike

Privacy and Confidentiality Distinguished from Security

• Privacy: The desire of a person to control disclosure of personal health information

• Confidentiality: The ability of a person to control the release of his/her information

• Security: The protection of privacy and confidentiality through policies, procedures, and safeguards

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Page 40: Author(s): Allen Flynn License: Unless otherwise noted, this material is made available under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike

Three Types of Data Security Safeguards

• Physical: Locked doors and locked cabinets• Technical: Encryption, Password

Authentication• Administrative: Policies, e.g., defining

minimum security standards for software used in an organization

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Page 41: Author(s): Allen Flynn License: Unless otherwise noted, this material is made available under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike

Key Security Concepts:Authentication and Authorization

• Authentication: You are who you say you are.• Authorization: What you are permitted, by

policy, to do/see in an information environment

41

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Authentication Factors

• Something you have – an ID badge• Something you are – a fingerprint scan• Something you know – a password

What is “two-factor” authentication?What would “three-factor” authentication be?

42

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43

Review• What Computation is• 3 Types of Information Systems• 4 Types of Knowledge• Modeling, incl. Data Modeling• Data Privacy & Security, Safeguards,

Authentication, and Authorization

~~~• Content & materials for Skill Module 2

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END

Page 45: Author(s): Allen Flynn License: Unless otherwise noted, this material is made available under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike

Image Attributions• The image “Human Limitations: Genomic Data and Decision Making” is courtesy of Bill Stead & Dan Masys• “Palette and brush” by ejmillan is in the Public Domain. • “Netalloy gears” by netalloy is in the Public Domain. • “Alarm clock” by Anonymous is in the Public Domain. • “Books” by Johnny Automatic is in the Public Domain. • “Brian diagram” by j4p4n is in the Public Domain. • “Health Informatics: a Systems Perspective” by Health Administration Press is All Rights Reserved. • “Tango computer” by warszawianka is in the Public Domain. • “The Computer and the Brain” by Yale University Press is All Rights Reserved. • “The Sciences of the Artificial” by the MIT Press is All Rights Reserved. • “Phone” by tonyk is in the Public Domain. • “Feverish woman” by Moini is in the Public Domain. • “Therapist” by tulvur is in the Public Domain.

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