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    ANATOMY OF LARYNX &

    TRACHEOBRONCHIAL

    TREE AND CONTROL OF

    BREATHING

    -Dr Ashish Pareek

    1st year residentDept of Anaesthesiology

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    Respiratory System

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    Lower Airway

    Larynx

    Tracheobronchial Tree (TB Tree)

    Trachea

    Bronchi

    Bronchioles

    Respiratory

    Terminal

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    Larynx

    Voice Box

    Function

    Prevents aspiration

    Generates sound for speech

    Conducts air between the pharynx andtrachea

    Creates pressure changes

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    Cartilages of the Larynx

    Composed of nine cartilagesThree unpaired cartilage

    Thyroid

    Cricoid Epiglottitis

    Three paired cartilages (six total)

    Arytenoid

    Corniculates

    Cuneiforms

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    Thyroid Cartilage

    The largest laryngeal cartilage is thethyroid cartilage

    Adams Apple

    Superior border has a V-shaped notch.

    Suspended from hyoid bone.

    Posterior wall is open.

    The true and false vocal cords are found on

    the interior of the larynx.

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    Cricoid Cartilage

    Resembles signet (class) ring.

    Inferior to Thyroid.

    Only complete ring of laryngeal structures.

    Inferior border is attached to the first C-shaped tracheal ring.

    The narrowest portion of the airway in aninfant.

    We use this fact when ventilating infantsas infant ET tubes do not have cuffs toseal the trachea.

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    Epiglottis

    Spoon-shaped cartilagewhich preventsaspiration by covering

    the opening of thelarynx duringswallowing.

    The tongue and the

    epiglottis are connectedby folds of mucousmembranes which forma small space called the

    vallecula.

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    Paired Cartilages

    The Arytenoids, Cuneiforms, and Corniculatesare all associated with movement of the vocal

    cords and are used in phonation.

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    Vocal Cords

    Two pairs of folds that protrude inward:

    Upper pair False cords

    Lower pair True cords

    The space between the vocal cords is called

    the rima glottidis or glottis

    Narrowest portion of the adult airway

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    Vocal Cords

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    Vocal Cords

    Vocal Cord AbductionCords are opening or moving away from

    the midline

    This occurs during inspiration

    Vocal Cord Adduction

    Cords are moving toward the midline or

    coming together

    This occurs during expiration

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    Histology of the Larynx

    Above the vocal cords

    stratified squamous epithelium

    Below the vocal cordspseudostratified columnar

    epithelium

    Trachea to respiratory bronchioles

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    Muscles of larynx

    Cricothyroid

    Posterior cricoarytenoid

    Lateral cricoarytenoid

    Transverse arytenoid Oblique arytenoid

    Aryepiglotticus

    Thyroarytenoid

    Thyroepiglotticus

    Vocalis

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    Nerve supply of larynx

    Motor nerves

    All the muscles of larynx are supplied by the

    recurrent laryngeal nerve except cricothyroidwhich is supplied by external laryngeal nerve

    Sensory nerves

    Internal laryngeal nerve- upto level of vocal foldReccurent laryngeal nerve- below vocal fold

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    Blood supply & lymphatic drainage of

    larynx

    Upto vocal folds - sup laryngeal artery & vein

    - anterosuperior group of

    deep cervical lymph nodes

    Below vocal fold - inf laryngeal artery & vein

    - posteroinferior group of

    deep cervical lymph nodes

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    Applied anatomy

    Laryngospasm

    A laryngeal reflex which will close thevocal cords inside the larynx

    Laryngospasm results from

    Extubations

    Near drowning

    Inhalation of noxious substances

    Smoke inhalation

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    Tracheobronchial Tree

    Two DivisionsCartilaginous Airways

    Primarily conducting airways; no gasexchange.

    Trachea to terminal bronchioles which isciliated for removal of debris, mucuslined

    Noncartilaginous Airways Both conducting airways and sites of gas

    exchange.

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    Cartilaginous Airways

    Trachea

    Main Stem Bronchi

    Lobar Bronchi

    Segmental Bronchi

    Subsegmental Bronchi

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    Lobar Bronchi

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    Trachea

    Generation 0

    11 13 cm long and 1.5 2.5 cmwide.

    Extends from Cricoid cartilage (6

    th

    cervical vertebrae) to the 2nd costalcartilage (5th thoracic vertebrae).

    15 -2

    0 C-shaped cartilages supportsthe trachea.

    Posterior wall is contiguous withesophagus.

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    The end of the trachea is called thecarina.

    This is the division of the trachea intothe right and left mainstem bronchi.

    The carina is located at approximatelyT5 or the Angle ofLouis.

    The surgical opening into the trachea iscalled a tracheostomy.

    2nd or 3rd tracheal ring.

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    Main Stem Bronchi Generation 1

    Trachea divides into the right and leftmainstem bronchi one for each lung

    Right Mainstem is wider, shorter and

    more verticalBranches at a 25 degree angle

    LeftMainstem

    Branches at a 40 60 angle Infants

    Both mainstem bronchi form a 55

    angle with the trachea

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    Newborn

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    Applied-Complications of Intubation

    During intubations, if the tube is advanced tofar, the tube will usually go into the rightmainstem bronchi.

    Lung inflation will be absent on the left but

    present on the right. Withdraw tube until bilateral sounds are

    heard.

    Failure to hear lung sounds or visualize chestinflation on either side means the tube isprobably in the stomach.

    Extubate the patient and re-attempt the

    intubation.

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    Aspiration

    Children who aspirate objects

    Foreign body usually lodged in right

    main stem bronchi secondary to theangle being less acute.

    Wheezing on right or absent lung

    sounds (breath sounds).

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    Lobar Bronchi

    Generation 2

    Lobar Bronchi correlate to the number of

    lobes of the lung.

    The right mainstem bronchi will divide

    into the right upper, right middle and

    right lower lobe bronchi.

    The left mainstem bronchi will divide into

    the left upper and left lower lobe

    bronchi.

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    Segmental Bronchi

    Generation 3

    Correlate with the segments of the lung.

    There are 10 segmental bronchi on theright.

    There are 8 segmental bronchi on the

    left.

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    Subsegmental Bronchi

    4th to 9th Generations

    1 to 4 mm in diameter

    Connective tissue containing:Nerves

    Lymphatics

    Bronchial Arteries

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    Non-Cartilaginous Airways Bronchioles

    10th to 15th Generation.

    1 mm in diameter.

    Simple cuboidal epithelium.

    No cartilage.

    Terminal Bronchioles

    Less than 0.5 mm in diameter.

    No cartilage (lack of support).

    Cilia and mucous glands disappear.

    Clara Cells appear

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    Blood Supply Bronchial Blood Supply

    --Bronchial arteries nourish thetracheobronchial tree

    --The arteries arise from the aorta and follow

    the tracheobronchial tree as far as theterminal bronchioles.

    --Beyond the terminal bronchioles pulmonary

    arteries & capillaries feed the airways &alveoli.

    --Normal bronchial blood flow is approximately

    1% of the cardiac output.

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    Respiratory Areas in Brainstem

    Medullary respiratory center

    Dorsal groups stimulate the diaphragm

    Ventral groups stimulate the intercostaland abdominal muscles

    Pontine (pneumotaxic) respiratory group

    Involved with switching between

    inspiration and expiration

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    Respiratory Structures in Brainstem

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    Rhythmic Ventilation

    Starting inspiration Medullary respiratory center neurons are continuously active

    Center receives stimulation from receptors and simulation from parts ofbrain concerned with voluntary respiratory movements and emotion

    Combined input from all sources causes action potentials to stimulate

    respiratory muscles

    Increasing inspiration More and more neurons are activated

    Stopping inspiration

    Neurons stimulating also responsible for stopping inspiration andreceive input from pontine group and stretch receptors in lungs.Inhibitory neurons activated and relaxation of respiratory musclesresults in expiration.

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    Modification of Ventilation

    Cerebral and limbic

    system

    Respiration can bevoluntarily controlled

    and modified by

    emotions

    Chemical control

    Carbon dioxide is major

    regulator

    Increase or decrease in

    pH can stimulate chemo-

    sensitive area, causing a

    greater rate and depth of

    respiration

    Oxygen levels in blood

    affect respiration when a

    50% or greater decrease

    from normal levels exists

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    Modifying Respiration

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    Regulation of Blood pH and Gases

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    Herring-Breuer Reflex

    Limits the degree of inspiration and prevents

    overinflation of the lungs

    Infants

    Reflex plays a role in regulating basic rhythm of

    breathing and preventing overinflation of lungs

    Adults

    R

    eflex important only when tidal volume large as inexercise

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    Ventilation in Exercise

    Ventilation increases abruptly At onset of exercise

    Movement of limbs has strong influence

    Learned component

    Ventilation increases gradually

    After immediate increase, gradual increaseoccurs (4-6 minutes)

    Anaerobic threshold is highest level of exercisewithout causing significant change in blood pH

    If exceeded, lactic acid produced by skeletal muscles

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    Effects of Aging

    Vital capacity and maximum minute

    ventilation decrease

    Residual volume and dead space increase

    Ability to remove mucus from respiratory

    passageways decreases

    Gas exchange across respiratory membrane

    is reduced