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Havener Eye InstituteDepartment of Ophthalmology

The Ohio State University

2008-2009

Annual Report

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e are establishing a tradition of excellence in phthalmology

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Thomas F. Mauger, MDirector and Chairmanhe Carl M & race C Baldwin Chair in phthalmologyavener ye nstitute epartment of phthalmology

Dear Friends and Colleagues,n phthalmology we have a unique opportunity to improve the

lives of others through the restoration of vision to the visually

impaired and blind

he epartment of phthalmology continued its growth dur-

ing the 00 009 academic year xciting developmentshave occurred in all three of our mission areas As the medical

center embarks on a one-billion dollar expansion the avener

ye nstitute has moved to a new facility at the ye and

ar nstitute he new avener ye nstitute site encompasses

our main clinical research and educational activities as well as

surgical facilities ur research and clinical faculty continue

to grow hile the new facility will help us meet our patients

needs it is the people within the facilities that bring our vision

to life on a daily basis e are very fortunate to have a dedicat-

ed and caring team of administrative and clinical staff facultyresidents and fellows who support each element of our mission

esearch efforts continue to expand in the areas of ocular tu-

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he epartment has been very active in clinical trials involving

age-related macular degeneration diabetic retinopathy pseudo-

tumor cerebri glaucoma and cataract surgery he residents

annual research program continues to improve in the quality of

the research and presentations

he ophthalmology residency program remains a key element

of our epartment Applications to the residency program are

at an all-time high in terms of quantity and quality hanks to

the efforts of esidency rogram irector Alan etson M and

rogram Coordinator rish ebish along with all of the in-

volved faculty and residents the program had another success-

ful year of interviews and selection concluding in yet another

outstanding class of residents

he resident surgical volume remains very high he faculty and

residents have new operating room facilities at the ationwide Chil-

drens ospital the Columbus A and at the new ye & ar

nstitute he fellowship program remains active with fellows cur-

rently in cornea glaucoma and retina hanks to aul eber M

the medical student lecture series remains one of the highest ranked in

the curriculum r etson has continued to improve the ophthalmol-RJ\FOHUNVKLS'XHWRWKHVHHIIRUWVRYHUYHSHUFHQWRI268PHGLFDO

students have selected ophthalmology as their career choice

ealthcare is at a critical point in the nited tates and globally

hile many medical centers are stagnant or retrenching we are for-

WXQDWHWRKDYHDPHGLFDOFHQWHUDQGDGHSDUWPHQWWKDWLVRXULVKLQJLQ

these challenging times t is our goal to continue to contribute to the

solution by training excellent physician leaders and by restoring sight

and preventing blindness through clinical care and research

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Chairman - Thomas Mauger, MD

Administrator - Robert LaFollette, MBA

Outreach Director - Laura Sladoje, BS

Program Coordinator - Christina Stetson, BA

Cover Photo: The new OSU Eye & Ear Institute (OEEI) with a highly skilled team of ocularspecialists and on-site surgical facilities, is central Ohios newest center for advanced eye care.

For more information, contact Ophthalmology Outreach at (614) 293-8760 or eye@osu.edu.

CONTENTS

1 Giving & Outreach

9 Education

11 Patient Care

15 Research & Grants

19 Division Reports & Awards

23 Publications & Presentations

28Faculty

NEW SPACE, NEW OPPORTUNITIES

INTERNATIONAL OUTLOOK

GIVING MAKES THE DIFFERENCE2

14

5

OUTSTANDING RESIDENTS9

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Giving2XWUHDFK

Vision helps us see a better world, butphilanthropy makes a better world possible.

John Christoforidis, MD

Havener Eye Institute lobby

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kestos $1, onation

A new tissue bank is being established at avener ye nsti-

tute due to a generous donation from real estate developers eorge

and ina kestos he $100000 donation was given to support

research on diopathic ntracranial ypertension ()

is a potentially

blinding disease thataffects women of

childbearing age

aised intracra-

nial pressure in these

patients can cause

blindness chronic

headaches hearing

loss ringing reduced

cognition and even

deathhe kestos generosity will enable the creation of a tissue bank of

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prior to the initiation of treatment toring these tissues will allow

researchers the opportunity to discover the underlying etiology of

as well as the effects of pharmaceutical interventions

he tissue bank will be instituted under the direction of r teven

.DW]DQDWLRQDOO\UHFRJQL]HGVSHFLDOLVWLQWKHHOGRIQHXURRSK-

thalmology atients from all over the world consult with r atz

on e has been involved in both clinical and basic science

UHVHDUFKRQ,,+IRU\HDUVDQGKHLVDVFLHQWLFDGYLVRUIRUWKHntracranial ypertension esearch oundation

r atz will be working with r ohn Mcregor eurosurgery

and r ubinoy as tolaryngology to create a team approach to

provide excellent clinical care to patients with and to spur multi-

disciplinary research strategies

eorge and ina kestos contribution will greatly increase our

knowledge of the causes and treatment of this debilitating disease

his will establish the avener ye nstitute as a center of

excellence in the care of patients with

'U0UV:LOOLDP+REEV'RQDWLRQAlumni Shares Thoughts on Giving Back

aving recently attended my 40th medical school

reunion celebrated 39 years of wedded bliss and

completed 33 years of rewarding litigation-free

general ophthalmology practice in ynchburg

irginia decided it was time to procrastinate no

ORQJHUEHIRUHFRQWULEXWLQJQDQFLDOO\WRWKHLO-

liam avener ye nstitute und

realize that none of us can stand on the sidelines for very long with-

out undermining the full potential of the epartment of phthal-

mology ecognizing familiar Columbus physicians and many of my

fellow residents from the early 1970s on the donor list reassures me

that the current residency program remains strong and the leadership

faithful to the core values and ongoing mission of the department

t is my hope that my gift to the avener und will assist in the sus-

tainability of ophthalmic education and quality eye care at hio tate

Sincerely,

William Hobbs, MD

Chief Resident , Class of 1975

2

6DJH0HPRULDO*LIW

arry M age M was a distiguished Columbus

ophthalmologist A Buckeye at heart he receivedhis undergraduate and medical degrees from he

hio tate niversity before becoming a resi-

dent at the phathlmology epartment

e was a veteran of the avy and served in

is dedication to his alma mater led him

to bequest $10000 to further the mission of the

epartment: excellence in research education

and patient care is support like the support of

so many former residents continues to validate

our efforts and encourage us to take every oppor-

tunity to make a difference

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OXPQL'LUHFWRU\

his year we unveiled the inaugural edition

of the avener ye nstitute Alumni

irectory he irectory was organized by

last name with a section by year for cross-

referencing

e scanned the many photos hanging onthe hallowed hallways of the department

showing alumni in their graduating year

his was done not only to make it so our

past residents can remain forever young

but will also make them easier to recognize

as they were

xcellence in education and clinical

training second to none has always been the goal of the residency

program at the epartment of phthalmology

rom the very beginning our faculty have committed to excellence inclinical training of ophthalmology residents his tradition of excellence

KDVSURYLGHGWKH'HSDUWPHQWZLWKDOXPQLWKDWDUHVRPHRIWKHQHVW

ophthalmologists in the country e are proud to have been a part of their

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2OXPQL5HFHSWLRQ

XWXPQLVDWLPHIRUUHHFWLRQDVOHDYHVIDGHDQG

summers warmth becomes a memory very fall

in the spirit of the season we host an annual alumni

reception at the American Academy of phthalmology

(AA) Celebrating our rich tradition of ophthalmic

excellence we welcome all of the alumni that the e-partment has trained over the years

his years Alumni eception was held at one of

Atlantas premier hotels the estin eachtree his

landmark hotel which towers over the city skyline was

the perfect setting for our annual reception that brings

together alumni from all over the country e were

happy that so many alumni were able to attend this

special event

3

Left Photo: eynell arder mith homas

Mauger M ebecca uennen M

Middle Photo: ohn ajka M on alker M

Right Photo: enry Croci M athryne Mcinney

ohn techschulte M

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his year we were fortunate to have a bonus

guest r andon Colling an ophthal-

mology resident who was 3rd in the 00orld ong-rive Championship r Colling

shared with participants his tips on how to

drive the golf ball over 400 yards

aving Clark ellogg and r Colling as

our special guests was even better than we

hoped said aura ladoje utreach irec-

tor hey were so friendly and personable

e had a great time and raised a lot of

money for the residents

e want to thank all of our sponsors in-

cluding ifth hird Bank tar phthalmics

aft aw irm and Morgan tanley to

name a few said r Alan etson esi-

dency rogram irector heir support

provides the resources and helps us educate

to the best of our ability After all the oph-

thalmologists that we are training today will

be taking care of our grandchildren; thats

not a responsibility that we take lightly

0DJQXVRQ)DPLO\*LIW$33,000 Supports Education

ames Magnuson son of r obertMagnuson recently shared My father

believed deeply in education and lovedto attend phthalmology rand oundse even continued to attend long after

he retired

r Magnuson created the obert Magnuson phthalmology ducationund at the avener ye nstitute beforehis death e recognized the need for ameeting room within the department andestablished the Magnuson Conferenceoom which is used for rand oundsresident and medical student educationresearch conferences and other depart-

mental activities r Magnusons wifelizabeth ighe Magnuson passed awayon anuary 11 007

riends of the Magnuson family havecontributed over $5000 in memory ofMrs Magnuson in addition to a familycontribution of $33000 e appreciatethe generosity and foresight of the Mag-nuson family and friends as the confer-ence room is utilized daily for diverseophthalmology activities

An early morning rain did little to dampen the

spirit of the enthusiasm that infused the 009

Buck olf Classic he heavily anticipated

event was held at the carlet course one of

the top collegiate courses in the nation he as-

sembled charity golfers looked forward to playing

WKHGLIFXOWFRXUVHEXWZHUHHTXDOO\H[FLWHGWRmeet former basketball player Clark el-

logg ellogg a lead BC basketball analyst

was an extremely charming and outgoing special

guest e signed autographs posed for photos

with guests and answered hard-hitting sports

questions while the golf course dried out

&ODUN.HOORJJ+HDGOLQHV*ROI2XWLQJ

Top: r Alan etson r andon Colling

Clark ellogg llen ressel and ina kestos

Middle: carlet olf Course Clubhouse

Bottom Left: esident r Andrea awchyn

Bottom Right: inners r ack ingle Michael

Baker r odd owling and r oug Baker

4

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Ghana & Nicaragua MissionsSaving sight in developing countries

ith the recent national discussion on healthcare it is easy to forget that such a debate is only pos-

sible because of the level of healthcare already available in the nited tates eveloping nations

are constantly struggling with a severe shortage of physicians trained staff and basic medical sup-plies ecognizing that need faculty and alumni from the avener ye nstitute have volunteeredtheir time and skills in icaragua and hana two of the poorest countries in the world

espite being the largest country in Central America icaragua is the second poorest country in theestern emisphere At least partially due to these factors medical care for the almost six millioncitizens of icaragua is limited and can be far more expensive than many icaraguans can afford

RKHOSDOOHYLDWHWKHGLIFXOWLHVIDFLQJLFDUDJXDVKHDOWKFDUHV\VWHPYROXQWHHUSK\VLFLDQVand staff operate a free clinic called el Centro acional de ftalmologa (the ational ph-thalmology ospital) in Managua icaragua Among these volunteers are some of our own

faculty r homas Mauger department chairman and r ebecca uennen one of ournewest faculty members n additional epartment alumni rs avid eorge ohn ajkaBrian tahl and on alker have been instrumental in creating an active collaboration with

the local ophthalmologists and furthering local ophthalmic training programs

n uly 009 rs Mauger and uennen traveled to icaragua to volunteer their time and

abilities and were also able to take ten donated corneas supplied by the issue Bank nterna-tional Because icaragua does not have a tissue bank these donated corneas were a particu-lar blessing to those requiring extensive surgery

here was one girl said r uennen about twelve or thirteen who needed a corneatransplant he was a beautiful girl but her cornea had been badly scarred After the surgery

she was crying she was so happy she could see again

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,QRQHZHHNWKH\WUHDWHGDERXWIW\SDWLHQWVUDQJLQJLQDJHIURPWZRWRHLJKW\KH\SHU-

formed corneal transplants and other necessary surgeries while the local physicians resi-

dents and staff at the hospital watched and learned

n a letter one grateful nurse shared her appreciation: hanks to our dear friends r omMauger and r ebecca uennen icaragua is a needy nation the patients hospital

and doctors here are very grateful

hana is another nation struggling to provide even basic eye care n addition to having toofew ophthalmologists for a population of 3 million almost 30% of hanaians are unable toafford healthcare as they live below the international poverty line of $15 per day

r Mauger and r avid Adam a community faculty member of the avener ye nstitute haveboth conducted trips to the impoverished nation April 009 was r Maugers third trip to the t

heresa ye Center in Akim Akroso hana n 005 and again in 009 r Adam traveled tohana to volunteer at the Bishop Ackon Christian ye Center in Cape Coast where he performedsurgeries and trained hanian physicians and residents e also provided instruction in phacoemulsi-

FDWLRQDPRGHUQFDWDUDFWVXUJLFDOWHFKQLTXHWRVRPHRIWKHORFDORSKWKDOPRORJLVWVLQHPD*KDQD

admire the many people in ophthalmology at hio tate who have done multiple missiontrips over the years said r Adam at Carroll M from ayton made several trips tohana with hio tate residents and that helped inspire me to go also estoring sight to

people who otherwise would not have access to care at any price helps me to get back to thebest reasons we all went into ophthalmology

he avener ye nstitute is proud of the faculty and alumni who have volunteered to help

out in these developing countries heir generosity inspires us all to greater levels of giving

Top: ye un/alk for ight participants in front of hio tadiumBottom: inners of the male and female categories r homas

Mauger and Marie Burleson

6

LEFT PAGE Top Left: r Mauger in hana Top Middle: r uennen with icaraguan patient Top Right: r Adam with ahanan patient Middle Left: ema hana Bottom Left: r Mauger and r uennen performing surgery in icaraguaRIGHT PAGELeft: roup of icaragua children at a food bankRight: wo icaraguan girls in their home

Run/Walk Supports International Missions

n an unusually beautiful and sunny ovember morning

runners lined up along the south side of the hio tadium

IRUWKHUVWDQQXDO\HXQDONIRU6LJKW,WZDVWKH

SHUIHFWGD\IRUWKHYHPLOHUXQDORQJWKH2OHQWDQJ\

iver rail

hose walking took the time to cheer the runners onbefore beginning a one-mile tour through the heart of

campus led by Brutus Buckeye ildly colorful autumn

leaves viewed against a backdrop of architecturally stun-

ning historic landmarks are a part of what makes

Campus a breathtaking place to visit

owever the purpose of the day was not just exhilarat-

ing competition or beautiful views All of the participants

were gathered in support of the nternational phthalmol-

ogy Missions which bring

much needed ophthalmiccare to developing countries

like hana and icaragua

roceeds from the ye un/

alk for ight go toward

sending ophthalmology

residents and fellows to help

this worthy cause

8/7/2019 AR_2008-2009

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$100,000 and abovearner & atti Bloweorge & ina kestos

$10,000 to $49,000erry Colphyllis avenerohn MartinMichael Martinrs homas Mauger & Carol axson

arry ager ale & Bonnie olze

$5,000 to $9,999r A & Ann Christoforidis

$2,500 to $4,999r avid Adamr Colleen Cebullars ack & Candace endershotr teven atzr arret & ristina Mouser

rs effrey & Mary ehler

$1,000 to $2,499r ouis Bloombergr atrick Carrollr enry & uzanne Crocir Mark ersmanr van & Marcie ilbertCarolyn reshemerCharles owarthohn auffmanobert aollette

r Alan & usan etsonohn Marakasr obert Mcinlayr Carl Minningr ames Mosesrs tephen & Ami rrr arl appar eonard uick

ancy obinsonoseph & ynne omanor Carl hin

aura & oug ladoje

$500 to $999ohn Alberinir ouglas Bakerr homas Batesr obert Chambersevin endersonr aurence arnsrs Carol & rank ollaritsr Charles & llen eone

r obert ytler teven Meadowsr Bernard & oris Mudrockr illiam enlandichard offenbaughaul itter rr Mac onningr dward chechterobert & elenor mithim & llen resselavid llmanr Albert an ossen

r aul eberr ohn ilding

$100 to $499Alan Alfordr eoffrey Allenirginia Armstrongr obin Beranr ohn Burnsr enneth Cahillr ohn Christoforidisr rederick avidorfr onathan avidorf

r ack ingler odd owlingCatherine endersonr loria lemingMargery orryelli oxMildred loverames & ally rossmanr eborah rzybowskiobert ammMonica ansonr ames arris

Ann avener

$100 to $499 (Cont.)Audrey enryirginia essohn ummel & Mary ayne oxr ary & ancy atzr Curtin elleyhonda ee itzlerDUEDUDDQGROr Carrie embach

r ichard embachr Max ernerlaine ewinr tuart Marksr effrey & ue McAdoor Mary ou Mcregorathryne Mcinneyr andy Mcaughlinim Mcemarill & arl Millironian Montgomeryora Moore

red & Cheryl icelyAlla udelMarlene airr hilip onnellrs eorge & uth aulsoneorgiana earsonaren ricerish ebishAnn oush wain ayreichard cheetzREHUWIH6KLIIBill peer

raham & Christina tetsonMike teyerr Michael toneChad tuckeyr Amit andonr onathan alkerames eanerBrian eeksobert enzisa illiamsonr & Mrs effrey inckoeorge intringer

r atie ulff

BuckEYEBenefactorsRecognizing Annual Contributions

January 1, 2009 - December 31, 2009

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%HQHIDFWRU5HFRJQLWLRQ:DOOHonoring the rich legacy of support

A beautiful new location allows for many new

possibilities ith the opening of the ye

& ar nstitute we welcomed the opportunity to

recognize all of our generous benefactors he

Benefactor ecognition all located in the lobby

proudly displays the names of those that have made

generous contributions to the epartment n ad-

dition information on upcoming events and new

developments is also on display

he ecognition all is a major focal point for

our new space he design brings together the

modern state-of-the-art facilities with the strong

tradition built by over 0 years of excellence in

ophthalmology

$1,000,000 and aboveCarl M. Baldwin*Grace C. Baldwin*

Warner & Patti BlowIrene D. Hirsch*

$500,000 - $999,999Martha Staub*

$100,000 - $499,999Jerry R. ColpPhyllis HavenerDr. William H. Havener*Drs. Thomas Mauger &

L. Carol Laxson

Dr. Milton C. Oakes*George & Tina Skestos

$50,000 - $99,999Dr. N. Douglas BakerDr. John BurnsDr. Kenneth CahillDr. Henry & Suzanne CrociDr. Frederick DavidorfLeo & Grace Faust*Drs. Jack & Candace HendershotDr. Roger & Margery Henderson*

Gayle Huffman*Eleanor Kilgore*Dr. Richard H. KeatesMary K. Laughlin*Dr. Alan LetsonDr. Holton LetsonDr. Robert & Elizabeth Magnuson*Dr. Torrence Makley*Dr. Robert & Helen McKinlayRuby Nowak*Dr. Dale & Bonnie SolzeRuth Tankersley*

Eldon J. Tobias*

$25,000 - $49,999Dr. Patrick CarrollDr. Robert Chambers

Helen Clabaugh*Fances ClontzHelen Coast*Helen Crane*Dr. William Hobbs Jr.Dr. Marilyn J. HuheeyKatherine Kessler*Lois Ann MoorDr. Alfred NicelyDr. Dick NisbetDr. Karl PappaDr. John StechschulteElmer Tankersley*Dr. Joel* & Ileen WachtelDr. Paul Weber

$10,000 - $24,999Dr. David AdamDr. Donald AndersonDr. James Andrew*Dr. Paul ArmstrongDr. William Banks IIIDr. Morris Battles*

Dr. Susan BenesDr. James Bennett*Joseph L. Bitonte*Dr. Wilbur Blount*Dr. Hans BredemeyerDr. Robert Bruce*Dr. Robert Bruce, Jr.Howard BurnettDr. Elson CraigDr. Robert DerickDr. Jack DingleGladys Dunlap*

Gilbert Eggleston

$10,000 - $24,999 (cont.)Harry Esbenshade, Jr.Dr. Sanders FarberDr. John Charles GarvinEdward Gerhold, Sr.*Dr. Gregory GibbFlorence Johnson*Dr. Fred & Audrey KapetanskyDr. John D. KayDr. Curtin KelleyDr. Charles Kunesh*Dr. Richard LembachDr. Jerrold LevinDr. Donald LewisDr. John MaderJohn L. MarakasDr. John Thomas MartinMichael T. MartinDr. W. Thomas MartinDr. Randy McLaughlin

Timothy McNemarAnn E. Meiling*Dr. Carl Minning, Jr.Dr. Garret MouserDr. James MosesDr. Robert* & Marlene ODairDr. E. Mitchel OpremcakDr. Richard OrlandoDorothy OsborneMaude Osborne*Dr. Paul RichardsGilbert & Ermal RobertsDr. Harry SageMary Ellen SharshalDr. Carl ShinDr. Richard SimmonsDr. James StewartDr. Ted Suie, Jr.*Dr. Lloyd TaustinePatti TewellDr. Peter UtrataDr. Albert Van FossenDr. Charles Zepp

Harold F. Zieg*

HavenerLegacy

8

Havener Legacy honors thoseindividuals who embody the spirit ofgenerosity of Dr. William Havener,their impact on the lives of ourpatients can never be measured.

*Indicates deceased

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EDUCATION The ophthalmologists that we

are training today will be taking

care of our grandchildren; thats a

responsibility we dont take lightly.

Alan Letson, MD

Third Year Residents (Top Photo)Carla Ford, MD, Ted Loizos, MD, Andrea Sawchyn, MD, Andrew Hendershot, MD,

and Anupama Horne, MD

Second Year Residents (Botton Left)Cedric Pratt, DO, Wendy Smith, MD, Rick Whitehead, MD, Katie Baston, MD,

and Landon Colling, MD

First Year Residents (Middle)Alla Kukuyev, MD, Vishal Verma, MD, Lena Chheda, MD, Aaron Davis, MD,

Cate Olson, MD, and Bill Lawhon, MD

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he avener ye nstitute is dedicated to developing

high-quality educational programs o this end wehave created 0/0 eminars a series of compli-

mentary continuing education events n the pring

RIWKHUVWRIWKHVHYHU\GD\HWLQDZDV

held at our ublin location Anterior egment ivi-

sion held eady Aim efract! which focused on

refractive surgery this past all

uture events will cover a variety of topics and will

qualify for continuing education credit e hope that

the success of these educational events will continue

to foster the community spirit that is an importantpart of the avener ye nstitutes Mission

Left to Right: Bob aollette r avid Castellano

r ebecca uennen and awn elfry

5HVLGHQW+XPDQLVPZDUG

Carla ord M a recent graduate of the

epartment of phthalmology was honored

with obyn owson umanism Award he

umanism Award is given to recognize a housestaff

member who is widely regarded as routinely

exhibiting attributes of ethics integrity caring

and compassion for patients and patients family

members; effective communication with patients

physicians and other healthcare professionals; and

excellent customer service

f the nearly 70 MC residents and fellowstraining r ord was one of 5 recipients of this

award r ord is very deserving of this award he

routinely received thank you letters from patients

while in training er nomination letter stated that

'URUGZRUNVVHOHVVO\DQGHIIHFWLYHO\6KHLV

enthusiastic about ophthalmology and her enthusiasm

is contagious r ord truly makes our department

better just by being in it hile we will certainly

miss having her around next year we will certainly

be proud to call her a graduate of our program

March Meeting &

Education Awards

he 5nd Annual ostgraduate ymposium in

phthalmology / he 3nd Annual Midwest

laucoma ymposium was held ebruary

7 009 at the ilton Columbus at aston

with nearly 00 participants in attendancehis years course directors loria leming

M rederick apetansky M and auleber M assembled an impressive lineupof guest speakers which included eter et-land M h ale euer M eon erndon M ydie Miller M oel chuman M ouglas hee Mohn Cohen M ay atz M Anup

hatana M

e are thankful for everyone that helpedmake this years ymposium such a success

AWARDS:

Katie Baston, MD

2009 First Place Resident Research Award (Tie)

Andrea Sawchyn, MD

2009 First Place Resident Research Award (Tie)

Anupama Horne, MD

2009 Third Place Resident Research Award

Bongsu Kim, MS

2009 Graduate Student Research Award

David Rogers, MD

2009 Makley-Battles Teaching Award

Michael Wells, MD

2009 Fellows Teaching Award

Amit Tandon, MD2009 Excellence in Teaching Award

10

Drs. Andrew Thomas, Carla Ford, and Alan Letson

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Vision is so important. Iwant to my patients to enjoytheirs for a long time.

Amit Tandon, MD

ta

,

New Topcon camera helps keep our physicians ahead of retinal disease.

Slack Fund Purchases Cameran the rapidly developing technology of digital cameras retinal imaging techniques

have been advancing quickly towards more sophisticated methods hanks to thegenerosity of Muskingum County Community oundation and the arah lacketina esearch und we have acquired a opcon C-5 etinal Camera

ohn Christoforidis M an retina specialist and assistant professor saidhis new camera will help to resolve diagnostic dilemmas and direct treatmentdecisions in patients with a wide array of macular disorders he C-5LQFRUSRUDWHVQHZIXQFWLRQVVXFKDVDXWRXRUHVFHQFHZKLFKHQKDQFHVLWVYHUVDWLO-

LW\ZLWKRXWVDFULFLQJ7RSFRQVXQVXUSDVVHGTXDOLW\RILPDJHUHVROXWLRQ

PatientCare

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3DWLHQWLQ)RFXVMildred Glover

Mrs Mildred lover is a retired nurse from hio

tate who was blind for several years due to a com-

bination of glaucoma and corneal edema he had

two failed cornea transplants and it seemed unlikely

that she would ever see again

n view of the failed transplants r homas

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plant or keratoprosthesis (-pro) on Mrs lover

evelopment of the Boston -pro began in the

196s and received A approval in 199 he -

pro is made of MMA (polymethyl methacrylate)

and consists of two basic parts he center button

or optic portion and the outer skirt are clamped

together on the outer rim of a donor cornea he

entire prosthetic cornea is then sutured to the host

cornea like a normal cornea transplant A soft ban-

dage contact lens is placed and the patient must useOLIHORQJWRSLFDODQWLELRWLFV7KHEHQHWRIWKH.SUR

is that the central portion will always remain clear

$IWHUWKHVXUJHU\VKHZDVGHOLJKWHGWRQGWKDWKHU

vision had improved to or the holidays she

was able to go tosee her family in orth Carolina

which she had not been able to do in years

3DWLHQW,Q)RFXVPatricia Shuter

atricia huter was told years ago that she had a slow-growing

cataract his clouding of the natural lens of the eye would mean

that the lens would eventually need to be removed and be replaced

E\DQDUWLFLDOOHQVLPSODQWNQRZQDVLQWUDRFXODUOHQV,2/KHQ

she came across an article on the Acryof e Multifocal

she cut it out and saved it he knew that when the time

came these were the lenses she wanted e implantsare designed to provide enhanced image quality and a full range

of visionup close far away and everything inbetweengiving

cataract patients the best opportunity to live life free of glasses

Mrs huter started seeing r Amit andon when he joined the

avener ye nstitute two years ago h think that he has been a

very wonderful guy to work with said Mrs huter es friendly

and hes fun arlier this year when she came in for her annual vision

exam r andon noticed that her cataracts had progressed and needed

to be removed e discussed cataract surgery and the different

options available to her hey both agreed that the e wouldgive her a full range of vision near and was the best

for her to eliminate her need for glasses he

possibility of being glasses-free after cataract

surgery was very attractive to Mrs huter who

has worn glasses since she was 1 years old

ow 85 she is thrilled that she no longer needs

to wear glasses for distance or near vision After

her cataract surgery she continues to maintain

her lifestyle and her driving ability

g ve er a u range o v s on near an was e es

for her to eliminate her need for glasses he

possibility of being glasses-free after cataract

surgery was very attractive to Mrs huter who

has worn glasses since she was 1 years old

ow 85 she is thrilled that she no longer needs

to wear glasses for distance or near vision After

her cataract surgery she continues to maintain

her lifestyle and her driving ability

3DWLHQWLQ)RFXVM

Mrs Mildred lover is a retired n

tate who was blind for several ye

bination of glaucoma and corneal

two failed cornea transplants and it

that she would ever see again

n view of the failed transplants

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plant or keratoprosthesis (-pro)

evelopment of the Boston -pro

96s and received A approva

pro is made of MMA (polymeth

and consists of two basic parts

or optic portion and the outer skirt

together on the outer rim of a don

entire prosthetic cornea is then sut

cornea like a normal cornea trans

dage contact lens is placed and thOLIHORQJWRSLFDODQWLELRWLFV7KHE

is that the central portion will alw

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vision had improved to o

was able to go tosee her family in

which she had not been able to do

12

t took me a long time toQDOO\UHPHPEHU,GLGQWKDYH

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atricia Shuter

$XWRXRUHVFHQFHSKRWRJUDSK\LVDQRQLQYDVLYHGLDJQRVWLFWRROVDLG&KULVWRIR-ridis t is very helpful in detecting and assessing patients with subtle lesions ina variety of retinal diseases that are not easily seen with other imaging modalityhis equipment can be used for early detection of unhealthy or damaged retinal

pigment epithelial cells () t can also monitor the effects of new treatments

he C-5 will aid in research of hereditary retinal diseases

Muskingum County Community oundation funded the camera through the arah

lack etina esearch und in a large part because arah lack was a long-time

patient of r Alan etson irector of the etina ivision know arah would

be extremely pleased with the use of her funds for this camera equipment that

detects early retinal damage etson said

7RSIURPOHIW : homas Mauger M

Andrew endershot M aul eber M

and Mildred lover (seated)

Bottom Closeup of eratoprosthesis mplant

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THENU

MBERSA

DDUPTO

BIGCHANG

E.

110,000Sqft Flooring

10,000Drywall Sheets

2,000Glass Panes

8/7/2019 AR_2008-2009

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150Lobby Seats

06.15.09Opening Day

150Lobby Seats

275,000Cable Ft

8/7/2019 AR_2008-2009

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Research*UDQWV

Research is an importantcatalyst for change. The effectsripple outward, changing lives

and saving sight.

Paul Weber, MD

esident Dr. Adam Cloud examines slides in the pathology lab for a research project.

8/7/2019 AR_2008-2009

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,Q'HFHPEHUWKH2FXODU+\SHUWHQVLRQ7UHDWPHQWWXG\2+7RIFLDOO\HQGHG

7KLVKLJKO\DFFODLPHGFOLQLFDOWULDOKDGEHHQLQH[LVWHQFHIRUIWHHQ\HDUV7KH+DYHQHU

ye nstitute epartment of phthalmology was one of only research sites na-

tionwide or the past 1 years r aul eber has served as rincipal nvestigator for this

important study

t is known that people with elevated eye pressure are at risk for developing glaucoma

+RZHYHUSULRUWRWKHUVWSKDVHRI2+7WKHUHZDVFRQLFWLQJHYLGHQFHDVWRZKHWKHUHDU-

ly medical treatment with eye pressure lowering drops was effective in delaying or prevent-

ing the onset of glaucoma he study enrolled over 16 participants with elevated

eye pressure but no evidence of glaucoma hey were randomized into two groups: treat-

ment with eye drops or no treatment After 5 years it was determined that the individuals

in the observation group were developing glaucoma at a much greater rate his conclusion

ZDVLQGHHGDQH[FLWLQJQGLQJEXWLWDOVRSRVHGDQRWKHUTXHVWLRQ,VWKHUHDSHQDOW\RUGLV-

advantage of delaying treatment for ocular hypertensive individuals? n a transition

was made from to to answer this question

articipants in the study have provided a unique and valuable information base

concerning the long-term effects of ocular hypertension his one study has yielded a

ZHDOWKRILQIRUPDWLRQ,WLVQRZNQRZQWKDWWUHDWLQJRFXODUK\SHUWHQVLRQLVEHQHFLDO

LQGHOD\LQJWKHRQVHWRIJODXFRPD,WLGHQWLHGUDFLDOULVNIDFWRUVIRU$IULFDQ$PHUL-

can individuals with elevated eye pressure he thickness of the clear front of the

eye (cornea) was also found to be a risk factor in the development of glaucoma

he data from is currently being collected and analyzed esults will be

available in the coming months

he study has already changed the way that physicians in this country

and around the world treat people with high pressure said eber n addition it

will stimulate new research that will lead to earlier diagnosis and better treatment

to help prevent glaucoma he clinical trial has been an important and very

EHQHFLDOVWXG\7KH+DYHQHU\H,QVWLWXWHLVYHU\SURXGWRKDYHEHHQDSDUWRIWKLV

landmark study

:LWKDOORIWKLVLQIRUPDWLRQ2+766WXG\*URXSKDVGHYLVHGD\HDU5LVN

)DFWRU(VWLPDWRUKWWSRKWVZXVWOHGXULVN7KLV5LVN)DFWRU(VWLPDWRUPD\

EHXVHIXOWRFOLQLFLDQVDQGSDWLHQWVLQGHFLGLQJWKHIUHTXHQF\RIWHVWVDQGH[DPL

QDWLRQVDQGWKHSRWHQWLDOEHQHWVRIVWDUWLQJWUHDWPHQW%HVXUHWRORJRQDQG

FDOFXODWH\RXUULVNIDFWRUIRUGHYHORSLQJJODXFRPD

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&OLQLFDO7ULDOV

avener ye nstitute is currently involved

in many clinical trials in nearly every area

of ophthalmology including Age-elated

Macular egeneration rug Comparison

tudy (CA) and iabetic Macular dema

ose Comparison tudy ()

Clinical trials are conducted to allow safety

DQGHIFDF\GDWDWREHFROOHFWHGIRUQHZ

drugs or devices hese trials can only take

place once satisfactory pre-clinical informa-

tion has been gathered and ealth Authority

thics Committee approval is granted

epending on the type of product and the

stage of its development investigators enroll

healthy volunteers and patients into small

pilot studies initially followed by larger scalestudies in patients that often compare the new

product with the currently prescribed treat-

PHQW$VSRVLWLYHVDIHW\DQGHIFDF\GDWDDUH

gathered the number of patients is typically

increased Clinical trials can vary in size

from a single center in one country to multi-

center trials in multiple countries

e want to thank all of our clinical trial

participants hese incredible volunteers are

helping to shape the future of medicine

CATT Study

he ational nstitute of ealth () spon-

sored CA study evaluates patients with wet

age-related macular degeneration (AM)

ualifying participants have untreated

newly diagnosed wet AM CA is being

conducted to compare two different AM

medications ucentis and Avastin he studywill also compare treatment schedules: half

RIWKHSDWLHQWVZLOOEHWUHDWHGRQD[HGYLVLW

schedule and half will be treated on an as-

needed visit basis ver a two-year period

the 1 participants will be closely monitored

E Study

he study sponsored by enentech

harmaceuticals evaluates the safety and

HIFDF\RI/XFHQWLVLQWUDYLWUHDOLQHFWLRQVfor diabetic macular edema (M)

,'LVWKHUVWWULDOXVLQJ/XFHQWLVIRU

patients with diabetes mellitus he par-

ticipants are randomized to one of three

treatment groups: 3mg 5mg or placebo

he study visits are monthly over a 3-year

period After years of study participation

all participants are eligible to receive the

full standard dose of 5mg he avener

ye nstitute has 11 participants in this trial

*URXQGEUHDNLQJ05,6WXG\

early 1 cases per year present with blockage of the centralretinal artery and vein as well as the posterior ciliary vessels e-

spite this we have no method that exists for imaging these vesselsto determine where the blockage has occurred because they arelocated behind the surface of the optic nerve (igures B C)

ohn Christoforidis M a retina specialist at the avener ye

nstitute has been working in collaboration with Michael noppM and other members of the epartment of adiology to im-age these structures with the use of a esla M machine inconjunction with a dedicated eye coil (igures A ) his iscurrently the only such system in the world and the initial imagesare already unprecedented in terms of their resolution

r Christoforidis presented the initial results at the Associationfor esearch in ision and phthalmology (A) on normalvolunteers this past year but there is still reasearch to be doner Christoforidis hopes for additional funding which would allow

for the continued improvement of the parameters and optimize theresolution of the imaging system

A B

C D17

Dr. John Christoforidis with a research patient

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GrantsChristoforidis JB () etson A avidorf Chang S C:anibizumab for Macular dema econdary to Central etinal ein cclusions

(C) enentech harmaceuticals 8

Christoforidis JB () etson A avidorf Chang S BA:anibizumab for Macular dema econdary to Branch etinal ein cclusion(B) enentech harmaceuticals 8

Christoforidis JB () etson A avidorf Chang S C rotocol :anibizumab vs riamcinolone vs ham as an adjunctive therapy for patientswith or severe on-roliferative iabetic etinopathy () who requireanretinal hotocoagulation () ational nstitute of ealth () 8-9

iabetic etinopathy Clinical esearch (C) etwork ( ite: Christo-foridis JB () avidorf Chang S) ntravitreal riamcinolone for ia-

betic Macular dema ational ye nstitute () 4-8

sei () ziengelewski A Breedlove Boland Boyer CC Cataland reenA rwin chuster arga-pangler Bowles eiland Arnold vans Bouttamy Craig E avidorf etson A Action to Control Cardiovascular

isk in iabetes tudy (ACC) ational nstitute of ealth () 4-9

iabetic etinopathy Clinical esearch (C) etwork ( ite: avidorf () Christoforidis JB Chang S) bservational tudy of iabetic Macu-lar dema after ational ye nstitute () 6-8

iabetic etinopathy Clinical esearch (C) etwork ( ite: avidorf () Christoforidis JB Chang S) ubclinical iabetic Macular demawith C ational ye nstitute () 6-8

iabetic etinopathy Clinical esearch (C) etwork ( ite: avidorf () Christoforidis JB Chang S) eribulbar riamcinolone for iabetic

Macular dema ational ye nstitute () 4-8avidorf () etson A Christoforidis J, Chang S CA: a multi cen-ter Comparison of AM reatment rial (Avastin vs ucentis) in the treatmentof wet AM ational nstitute of ealth 8-1

etson A () avidorf Christoforidis JB : A hase ouble-0DVNHG0XOWLFHQWHUDQGRPL]HGKDP&RQWUROOHGWXG\RIWKHIFDF\DQGDIHW\RIDQLEL]XPDE,QHFWLRQLQXEHFWVZLWK&OLQLFDOO\LJQLFDQW0DFXODUdema with Center nvolvement econdary to iabetes Mellitus enetechharmaceuticals 6-1

etson A () avidorf Christoforidis JB Chang S hase pen a-

bel Multi-center rial of Maintenance intravitreous injections of Macugen given

every 6 weeks for 48 weeks in subjects with subfoveal neovascular AM initiallytreated with a modality resulting in maculopathy improvement yetech har-maceuticals 6-8

etson A () Christoforidis JB avidorf Chang S Age-elated yeisease tudy (A): A Multi-Center andomized rial f utein ea-xanthin and mega-3 ong-Chain olyunsaturated atty Acids (ocosahexae-noic Acid A and icosapentaenoic Acid A) in Age-elated Macularegeneration ational ye nstitute ational nstitute of ealth 6-1

Mauger T () embach angel ME arder mith ates and riskfactors for fungal keratitis among contact lens wearers ohn opkins 6-8

Mauger T () embach Castellano arder mith A double-masked randomized study of the safety and ef-fectiveness of M as an agent for selective staining of theanterior capsule during cataract surgery Aqumen Biopharma-ceuticals -8

oberts CJ () itsky A embach eber A Measurement and valuation of the

lastic and iscous roperties of the Cornea inlaucoma Columbus oundation 6-8

eber A () iu J oberts CJ he mpactof Corneal lasticity on and CC measure-ments in laucoma Management Columbusoundation 9-1

eber A () Baker apetansky er-ick cular ypertension reatment tudy ()

ational ye nstitute () 1994-9

18iew of downtown Columbus from S Eye & Ear nstitute

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Division Reports

We have specialists to treat every condition,so patients get the care they need, fast.Steve Katz, MD

Anterior egmentRebecca Kuennen, MD

he Anterior egment ivision includes the areas of Cornea and

xternal isease Comprehensive phthalmology ptometry

and efractive urgery he division is actively involved in

teaching research and clinical care

r ulie Meier joined the epartment as a comprehensive

ophthalmologist in 8 he completed her residency at the

niversity of isconsinMilwaukee Along with r avid

Castellano and r Amit andon this team provides compre-

hensive ophthalmic care to the university community and at our

outreach clinics hey are integral to our resident clinical educa-

tion on campus and through the Columbus A clinic hey also

provide outstanding role models of comprehensive ophthalmol-

ogy to our residents and medical students r elly ingsbury

joined the epartment to provide optometric care includingcomprehensive examination contact lens services and visual re-

habilitation services r ara uffman joined the department to

provide visual rehabilitation service to the patients at the odd

all ehabilitation ospital at the Medical Center r

andy Mcaughlin continues to provide comprehensive exami-

nations and contact lens services rs ingsbury uffman and

Mcaughlin are involved in resident education

Columbus A where S faculty and residents provide care to our nations veterans.

8/7/2019 AR_2008-2009

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*ODXFRPD'LYLVLRQPaul Weber, MD

he laucoma ivision feels that patient care educationand research are all critical to out mission

hanks in part to the generosity of erry Colp a patient andbenefactor we have state-of-the-art equipment to provide

the most up-to-date care for our patients: the ptovue p-tical Coherence omographer can detect glaucoma damagein some patients before any other abnormality is foundhis results in earlier treatment and will result in fewer

patients going blind from glaucoma he ascal ynamicContour onometer can detect those patients whose eye

SUHVVXUHLVIRXQGWREHDUWLFLDOO\ORZZKHQPHDVXUHGZLWKthe standard tonometer his results in better managementof their glaucoma and again fewer cases of blindness ofurther enhance patient care we have added a full-time

glaucoma specialist to the division M yad Azrak M

is addition has resulted in expanded medical and surgicalofferings for our patients and referring doctors

n the research arena we just completed participation in the cular ypertension reatmenttudy his 15 year - funded study was a ground-breaking study that has alreadychanged how physicians around the world diagnose and treat glaucoma and will have a majorLPSDFWRQSUHYHQWLQJORVVRIYLVLRQ7KHQGLQJVIURPWKLVVWXG\KDYHJHQHUDWHGDZKROHQHZarea of glaucoma research the area of biomechanical properties of the eye and their effects in

glaucoma artnering with our faculty from Biomechanical ngineering rs Cynthia ob-erts and un iu the avener ye nstitute has some of the leading minds in this importantarea umerous clinical and laboratory research projects are underway in this area

n the education mission laucoma has been educating medical students ophthalmicpersonnel ophthalmology residents residents of other medical disciplines optometristsand practicing physicians his past years Annual ostgraduate ymposium partnered withthe Midwest laucoma ociety to host national and international glaucoma experts in ourlaucomahats ried and rue and ew symposium t drew over 15 physicians

he ophthalmology module presented to the second-year medical students once again re-ceived one of the highest ratings by the students

he glaucoma division takes great pride in contributing in a very positive and impactingway in all three mission areas critical to the success of the hio tate niversity Medical

Center and avener ye nstitute

20

he Cornea ervice remains active performing a full spec-

trum of corneal procedures including penetrating lamellar

and endothelial keratoplasty keratoprosthesis corneal stem

cell transplants and phototherapeutic keratoplasty he

Cornea ervice is routinely consulted for the evaluation of

complex external disease problems such as acanthamoeba

and fungal keratitis ocular pemphigoid herpetic keratitis

and ocular surface neoplasia he service currently includesrs ichard embach Matthew angel homas Mauger

and ebecca uennen r Matthew hr completed his

cornea fellowship in une of 9 and took a position on the

staff of the Cleveland Clinic oraine Campus r Andrew

endershot was the Chief esident in phthalmology and

is the current cornea fellow for 91 he division is

conducting clinical research trials with A use in diabet-

ic cataract surgeries corneal cross-linking and intra-operative

corneal topography

he phthalmology ervice at the Columbus A clinic is led

by r Carol axson he new A outpatient clinic was opened

less than one year ago and patient visits and surgeries continue

to grow he new ambulatory surgery center at the A started

treating eye cases in uly of 9 and the volume and spectrum

of cases has continually increased Currently three residents

are in attendance at the A and the supervising ophthalmolo-

gists cover the entire spectrum of eye disease ensuring that

veterans in central hio get state-of-the-art eye care

he ivision has been involved in two ongoing internationalmissions r Mauger performed cataract and severe pte-

rygium surgeries in the village of Akima Akosa hana in

April 9 rs uennen and Mauger traveled to Managua

icaragua in uly of 9 and performed successful kerato-

plasty procedures thanks to the donation of corneal tissue by

issue Banks nternational rs uennen and Mauger had

discussions with the Ministry of ealth in icaragua about

creating a new eye bank in their country here are plans for

additional trips during the coming year

8/7/2019 AR_2008-2009

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2FXORSODVWLF'LYLVLRQKenneth Cahill, MD

he culoplastic urgery ervice is commit-

ted to excellence in clinical care research and

teaching Active participation in medical school

teaching occurs in core curriculum instruction

physical diagnosis instruction clinical rota-

tions elective rotations and research projectsesident teaching is organized with didactic

OHFWXUHVVWDIQJRI2FXORSODVWLFV&OLQLFVDWWKH

campus and the A Clinic weekly surgery

and clinic for phthalmic lastic urgery dur-

ing the second year pediatric rotation and third

year resident culoplastic urgery rotations he

American ociety of phthalmic lastic and

econstructive urgery (A) ellowship

training program compliments the residency

teaching program and provides additional edu-

cational and research resources to the residents

Members of the culoplastic service are ohn

Burns M enneth Cahill M elly ver-

man M ill oster M teven atz M

evin Michels M and ames Moses M

ocal regional and national instructional cours-

es are presented in oculofacial surgery pediatric

oculoplastics cosmetic facial surgery blepharo-

spasm thyroid eye disease and ptosis esearch

presentations and publications during this past

year included topics of ptosis the lacrimal out-RZV\VWHPPLQLPDOO\LQYDVLYHVXUJHU\WK\URLG

eye disease eye socket reconstruction injectable

WLVVXHOOHUVDQGIDWJUDIWLQJ'U%XUQVFRP-

pleted a prospective masked study of a new form

of botulinum A toxin in the treatment of benign

essential blepharospasm e have developed

techniques for virtual endoscopy of the lacrimal

drainage system his enables us to visualize

anatomical structures and pathology that were

previously only visable with surgical dissection

1HXUR2SKWKDOPRORJ\'LYLVLRQSteven Katz, MD

he euro-ophthalmology ivision continues to con-tribute to the epartmental mission in the core areas

of clinical care teaching and research epartmental

faculty including avid irsh usan Benes and te-

ven atz are responsible for the esident lecture series

as well as medical student teaching in neuro-ophthal-

mology r irsh organized the esident morning

lecture series and was an active clinical instructor

rs irsch and Benes were regular contributors to the

rand ounds focused on neuro-ophthalmology

r atz hosted a ymposium on eadache Manage-ment on ebruary 9 at hio tate where he

also gave an update on the iagnosis and Manage-

ment of eadache in iant Cell Arteritis r atz

VHUYHVDVDVFLHQWLFDGYLVRUIRUWKHIRXQGDWLRQDQG

regularly sees problem patients nationally who are

referred through the foundation

r atz had three publications in peer reviewed jour-

nals and one book chapter published in the past year

e was also a manuscript reviewer for the journals

phthalmic lastic econstructive urgery and

ye r atz was a grant reviewer for eye and vi-

sion research for the American nstitute of Biological

ciences and nited tates Army Medical esearch

and Material Command (as part of the Congressio-nally irected Medical esearch rogram) in 9

e also continues to review grants for the Ann llis

und at the Columbus oundation n 9 r atz

was again selected for Best octors in America by his

peers and he was also appointed to the orrence A

Makley esearch rofessorship in phthalmology

n anuary 1 we will embark on A Multicenter

ouble-blind andomized lacebo-controlled tudy

of eight eduction andor ow odium iet plus

Acetazolamide vs iet plus lacebo in ubjectswith idiopathic ntracranial ypertension with Mild

isual oss he study was proposed by C

and is sponsored by the ational ye nstitute hio

tate is a study center for the trial and r atz is the

rincipal nvestigator here are currently 3 other

clinical trials going on in the division

he division received a generous donation of

1 from eorge and ustine kestos toward

the generation of a tissue bank for patients with

diopathic ntracranial ypertension

21

Director of outpatient surgery, inda Meikle, giving a tour of a surgical suite

8/7/2019 AR_2008-2009

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Pathology DivisionElson Craig, MD

or the 8-9 academic year a total f 556

FDVHVZHUHH[DPLQHGUHSRUWHGDQGOHGLQWKH

ivision Archives of phthalmic athology

his total included the following cases:

1 nucleations including 1 malignant melanomas

6 viscerations

3 rbital tissues including lacrimal gland biopsies

51 emporal artery biopsies

155 ye lid lesions

85 Conjunctival lesions

153 Cornea tissues including 6 escemets

membraneendothelial specimens

9 ris tissue including 1 malignant memanoma

ntraocular lens removal14 Miscellaneous specimens including 6 foreign

bodies 1 optic nerve sheath specimens

nasal lacrimal tissues

34 utside slides for consultation

he ivision of phthalmic athology in the pro-

vides support to faculty residents and students when

preparing presentations publications and for research

projects he ivision has an extensive Archives of

pathology cases and microscopic and photographic

equipment available to support these activities

3HGLDWULF'LYLVLRQGary Rogers, MD

he outpatient clinic visits once again shows strong

numbers he report indicates we had 956 clinic

visits for this reporting period which is a 1

increase from last year he clinic continues to be

VWDIIHGE\WKUHHUVWDQGVHFRQG\HDUUHVLGHQWVIURP

he hio tate niversity and two optometrists 5days a week

he ediatric ivision continues to be enormously

active surgically continuously showing improved

numbers in the surgery center he division partici-

pates in both funded and unfunded research everal

amblyopia protocols and a randomized nasolacri-

mal duct study are being conducted in association

with the ediatric ye isease nvestigator roup

() rs on Bremer and ick olden are

the rincipal nvestigators for these trials

arry eguire h continues to work with the

epartment of phthalmology in functional M

research with an interest in congenital ocular motor

nystagmus An eye tracker in the M scanner has

been acquired for these studies r avid ogers

has been active in teaching and in clinical research

r avid ogers submitted six abstracts for pre-

sentation at the American Association for edi-

atric phthalmology meeting in an rancisco

CA his could represent the greatest number

of abstracts presented from a single department

r avid ogers and r ick hitehead won a

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entitled Corneal ower Measurements in ixating

HUVXV$QHVWKHWL]HGRQ[DWLQJ&KLOGUHQVLQJ

a andheld eratometer r ary ogers was

the honoree of the avid riendly award at the

Costenbader ociety Annual Meeting in Annapolis

M this past eptember

am very pleased with the progress of our division

and its continued success e have worked with the

hospital and have increased lab space freeing up

space for our clinic t continues to be our goal to be

a leader in the research of fM and changes to the

visual cortex in patients with amblyopia and nystag-

mus has recognized our previous research

with sinemet and amblyopia and has just completed

WKHUVWPXOWLFHQWHUVWXG\LQDPEO\RSLDLQYROYLQJthe treatment of older children using a similar le-

vodopa-carbidopa combination

22ediatric atient

8/7/2019 AR_2008-2009

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5HIUDFWLYH6XUJHU\David Castellano, MD

n the spring of 9 the efractive urgery ivision implemented

the Allegretto A xcimer aser his laser utilizes ave-

front-ptimized software which considers the unique curvature of

the eye preserves quality of vision and addresses the spherical dis-

tortions that may induce glare and affect night vision e use the

Allegretto A laser in conjunction with the ntraase femato-second () laser which allows us to perform bladeless customized

refractive treatments while preserving more corneal tissue

ith the large range of correction even patients with high

degrees of myopia hyperopia and astigmatism are typically

treatable Another correction option is monovision or blended

correction for patients over 4 with presbyopia ur surgical

outcomes have been excellent and our patients are extremely

VDWLVHGZLWKWKHLUUHVXOWV

oric and Multifocal intraocular lenses continue to be popular

treatment options for patients needing cataract surgery and de-

siring the best possible post-operative vision oric intraocular

lenses allow patients to obtain astigmatism correction during

cataract surgery and multifocal lenses are used to correct both

distance and near vision

Research DivisionDeborah Grzybowski, PhD

he esearch ivision which covers all subspecialties in phthalmology continued to

expand and attain national and international recognition he department now has research ef-

forts in retinal detachments cataract and macular edema ry AM topical inhibitors

ZRXQGKHDOLQJPHODQRPDUHJXODWLRQRIFHUHEURVSLQDOXLGRXWRZFRUQHDOELRPHFKDQLFVLQ

normal and pathologic eyes glaucoma idiopathic intracranial hypertension bacterial conjunc-

tivitis fungal keratitis managing ocular hypertension and others he addition of Mohamed

Abdel ahman M h in the etina ivision gives the epartment expertise in both

pathology and genetics and adds uveal melanoma genetics research to our program

or the 9 academic year the epartment of phthalmology received 9 new research awards

and continued work on 1 multiple year grants hese awards focused on age-related macular

degeneration corneal biomechanics in normal and pathologic eyes diabetic macular edema

retinal vein occlusion glaucoma idiopathic intracranial hypertension bacterial conjunctivitis

fungal keratitis managing ocular hypertension and others unding sources included the ational

nstitutes of ealth the Columbus oundation and the hio ions ye esearch oundation as

well as numerous industry awards

7KHUHVHDUFKQGLQJVSURGXFHGSHHUUHYLHZHGSXEOLFDWLRQVDQGERRNFKDSWHUVDQG

were reported in multiple presentations at a variety of phthalmology-related conferences

around the world including the American Academy of phthalmology and A the ma-

RUDQQXDOLQWHUQDWLRQDOVFLHQWLFPHHWLQJIRUYLVLRQUHVHDUFK

7KHUHVLGHQWUHVHDUFKSURJUDPH[SRVHVWKHUHVLGHQWVWRWKHVFLHQWLFUHVHDUFKSURFHVVE\LQYROY-ing them with a faculty mentor in either basic science or clinical studies Many residents choose

a project that spans all three years of their residency to allow adequate time for a fully developed

project All residents fellows and medical students are encouraged to attend A and present

their research raduate students in either an M or h program are advised by either Cynthia

oberts h or eborah rzybowski h in their vision-related research n addition some

RIRXUDIOLDWHGIDFXOW\DOVRDGYLVHJUDGXDWHVWXGHQWVLQYLVLRQUHVHDUFK

Many small research projects are supported by the hio ions ye esearch oundation

from which the department receives an annual endowment he past year has witnessed

many accomplishments in the esearch ivision accomplishments that move us to the

forefront of vision research in multiple areas

23

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efractive surgery patient

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Retina DivisionAlan Letson, MD

he etina ivision faculty for the 89 aca-

demic year included ohn Christoforidis M usie

Chang M red avidorf M aul urz M

and Alan etson M r urz joined the faculty in

ovember 8 after having completed fellowships

in Medical etina at uke as well as two additional

one year fellowships in veitis and cular enet-

ics at the Casey ye nstitute he end of the year

was highlighted by the move to the new owdy

ields facility acquisition of a eiss Cirrus pectral

omain C an additional eiss tratus C and

upgrades for the other tratus machines for clini-

FDOWULDOZRUNDGGLWLRQDOXQGXV$XWRXRUHVFHQFH

capability for use at all retina locations and two new

Alcon Constellation itrectomy units for use in the

new surgical facility at owdy ields

atient care activity included over 9 patient vis-

its with over diagnostic imaging procedures

for the division and the department including time

and spectral domain C luorescein Angiography

A and B scan iagnostic ltrasound (anterior and

posterior segments) and undus Auto luorescence

he surgical retina team performed over 139 major

vitreo-retinal procedures ver 13 intravitreal

injections were given for wet AM and other causes

of C and macular edema red avidorf M

managed the ocular oncology portion of the service

ZLWKDVWHDG\LQRZRIRFXODUPHODQRPDSDWLHQWV

HVHDUFKHIIRUWVLQFUHDVHGVLJQLFDQWO\GXULQJWKH

year ed by research manager aura ladoje and

clinical coordinators ill alerno ill Milliron

and athy Mcinney the division was actively

involved in studies sponsored by ational ye

nstituteational nstitutes of ealth C and

enentech Applications and preparations were

made for additional clinical trials and funding for

studies to begin in the upcoming year including

studies on retinal detachments cataract and macu-

lar edema ry AM and topical inhibitors

cott avage and his team of photographers of

tephen helley and Amanda Barnett contributed

to imaging for these retinal trials as well as other

trials performed by other departmental divisions

n addition to the sponsored clinical trials listed

below red avidorf continued his research in

ocular melanoma ohn Christoforidis has

been developing high-resolution M for

ocular diseases in conjunction with the

radiology department and completed

studies on wound healing and

inhibitors in mouse models

he basic science research effort was

boosted by the addition of Mohamed

Abdel ahman Mh who has a

h in athology from hio tate and

recently completed a -year fellowship in

cancer genetics at in 6 e is cur-

rently working with r avidorf on various projects

involving uveal melanoma genetics

he division maintained its teaching activity by sup-

porting two retinal fellows Mark Barsamian

and Mike ells M and working with residents

LQWKHLUUVW\HDUDQGVHFRQG\HDUUHWLQDURWDWLRQV

e have medical students also rotate on the service

etina faculty deliver weekly retina lectures to resi-

dents and hold imaging conferences with residents

and fellows he faculty also serves as preceptors for

resident research projects and is active in the cur-

riculum of the College of Medicine

AMERICAS BEST DOCTORSwenty years ago Best octors was founded

by two arvard Medical chool physicianswith the vision of making the best medicalexpertise available around the world orColumbus hio this years list is comprisedentirely of phthalmology faculty an

appreciated but not surprising distinction

ouglas Baker M*obert Bennett M*obin Beran M*ohn Burns M*enneth Cahill M*avid Castellano Mobert Chambers *ouis Chorich M*ohn Christoforidis Mrederick avidorf Mobert errick M*

ack ingle M*Alice pitropoulos M*Avrom pstein M*elly verman M*ill oster M*teven atz MCurtin elley M*ebecca uennen M Carol axson Mavid ehman M*Carrie embach *ichard embach M

Alan etson MMark omeo M*homas Mauger M Mitchel premcak M*arl appa M*ohn techschulte M*eter trata M*aul eber M

,QGLFDWHVDFRPPXQLW\IDFXOW\PHPEHU)RU

DFRPSOHWHOLVWRIRXUFRPPXQLW\IDFXOW\YLVLW

ZZZH\HRVXHGXGLUHFWRU\FRPPXQLW\

24

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Publicationsresentations

S Eye & Ear nstitute conference room for on-site presentations and continuing education

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Publications

iabetic etinopathy Clinical esearch (C) et-work ( ite: Christoforidis JB () avidorf Chang S) ptical Coherence omographyMeasurements and analysis methods in optical coher-ence tomography studies of diabetic macular edemaphthalmology 115 (8):1366-131e1 Aug 8

iabetic etinopathy Clinical esearch (C)etwork ( ite: Christoforidis JB () a-vidorf Chang S) ffects of dilation onelectronic- visual acuity (A) in diabetic

patients nvestigative phthalmology isualcience -ub ct 8

iabetic etinopathy Clinical esearch (C)etwork ( ite: Christoforidis JB () avi-dorf Chang S) Comparison of ptical Coher-

ence omography etinal hickness Measurementsin iabetic Macular dema with and without ead-ing Center Manual rading from a clinical rialserspective nvestigative phthalmology isualcience 5 ():56-566 eb 9

iabetic etinopathy Clinical esearch (C) et-work ( ite: Christoforidis JB () avidorf Chang S) iabetic Macular dema: hat isocal and hat is iffuse? American ournal ofphthalmology 146 (5):649-55 ov 8

iabetic etinopathy Clinical esearch (C) etwork( ite: Christoforidis JB () avidorf ChangS) An bservational tudy of the evelopment of ia-

betic Macular dema ollowing anretinal (catter) ho-tocoagulation () iven in 1 or 4 ittings Archives inphthalmology 1 (): 13-14 9

ubow M rzybowski M etson A en-nebohm and usac luorescein and indo-cyanine green angiographies in usac syndrome

etina 8(8): 114-5 ct 8

apoor atz SE rzybowski M ubow M&HUHEURVSLQDOOXLG2XWRZ$QYROYLQJHUVSHF-tive Brain esearch Bulletin (6): 3-334 8

Baker immerman A rzybowski MMcaughlin atz SE friem B ood ptical uality and mpact esistance Compari-sons of ootball elmet aceshields ptometry9(8):455-63 Aug 8

limcher A olman ubow M rzybowskiM[YLYRPRGHORI&RXWRZWKURXJK+X-PDQ$UDFKQRLGUDQXODWLRQV0HFKDQLVPVRIXLGRXWRZDQGLPSOLFDWLRQVIRUGLVRUGHUVRI&KR-meostasis nvestigative phthalmology isualcience 49(11):41-8 ov 8

rzybowski M and ubow M cular isease:Mechanisms and Management n: evin A and AlbertM ed diopathic ntracranial ypertension (diopathic

seudotumor Cerebri) lsevier imited; ear Chapter 39

oyle C atz SE and ewton B rognosisof efractory eurosarcoidosis Altered by ha-lidomide: Case eport ournal of Medical Caseeports : (pp 1-5) 8

Criden M atz, SE embach Corneal andConjunctival oreign Bodies n: Brightbill Mc-onnell Mchee C arjo A erdarevic Corne-al urgery: heory echnique issue 4th dition

Mosby lsevier t ouis M 9 133-13

uhler B mith iles auer A ertheimM urz urz A im Mackensen ickard7'RVHQEDXP7,QL[LPDE7KHUDS\IRUHIUDF-tory veitis: -ear esults of a rospective rialArchives of phthalmology 1(6) un 9

urz A uhler B Choi osenbaum LWX[LPDEIRU7UHDWPHQWRI2FXODU,QDPPDWRU\isease: a series of four cases British ournal of

phthalmology 93(4) Apr 9

Martin hang urz A ose C Chen u lanck avey M osenbaum he efect in Blau yndrome oes not result in excessinterleukin 1 activity Arthritis heumatism6(): 611-618 eb 9

urz A ntravitreal teroid njections n:

Becker M and avis M d urgical Manage-

PHQWRI,QDPPDWRU\\H'LVHDVHSULQJHUHUODJBerlin eidelberg; ul 8 5-16

he Action to Control Cardiovascular isk in ia-betes tudy (ACC) roup ( ite: Craig

E, avidorf , etson A) ffects of ntensivelucose owering in ype iabetes ew nglandournal of Medicine 358(4): 545-559 un 8

avitt B obson uinn ardy ung B

ood with the arly reatment for etinopa-

thy of rematurity Cooperative roup ( ite:etson A) Astigmatism in the arly reatmentfor etinopathy of rematurity tudy indings to 3ears of Age phthalmology 116:33339 9

ewis J nellinger A Mahmoud AM MaugerT ffect of oft Contact enses on pticalMeasurements of Axial ength and eratometryfor Biometry in yes with Corneal rregularitiesnvestigative phthalmology isual cience 49:

331-338 8

iu J and e Corneal stiffening leads to higher elevation associated with an increase of intraoc-XODUXLG,QYHVWLJDWLYH2SKWKDOPRORJ\DQGLVXDOcience 5(5): 4-9 9

e and iu J A quantitative ultrasonic spectros-copy method for non-invasive determination of corneal

biomechanical properties nvestigative phthalmol-ogy and isual cience 5: 5148-5154 9

26

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Presentations

Abdel-ahman AM etinoblastoma a paradigm

for the practice of clinical cancer genetics Children

Cancer ospital of gypt Cairo gypt April 16

9

rzybowski M Arachnoid pathways for C

absorption ydrocephalus 9 orkshop:

mproving utcomes in ydrocephalus: Bridgingthe ap between Basic cience and Clinical Man-

agement Baltimore M eptember 14 9

rzybowski M etinoid signaling pathway pro-

teins in human arachnoid membrane: ole in regulat-

ing intracranial pressure ydrocephalus 9

orkshop: mproving utcomes in ydrocephalus:

Bridging the ap between Basic cience and Clini-

cal Management Baltimore M eptember 19

9

rzybowski M Arachnoid pathways for C

absorption Ahmedabad Academy of phthalmol-

ogy Cataract and efractive urgery ymposium

Ahmedabad ujarat tate ndia March 9

rzybowski M op ive to tay Alive: ive

euro-ophthalmology earls and itfalls for the

eneralist: apilledema with isual oss oint

Meeting of the American Academy of phthalmol-ogy (AA) and uropean ociety of phthalmology

() orth American euro-phthalmology oci-

ety (A) ymposium Atlanta A ovember

1 8

rzybowski M ision research from an ngi-

neering erspective College of ptometry

Columbus August 14 8

atz SE op ive to tay Alive: ive euro-

ophthalmology earls and itfalls for the eneralist:

iant Cell Arteritis oint Meeting of the American

Academy of phthalmology (AA) and uropean

ociety of phthalmology () orth American

euro-phthalmology ociety (A) ympo-

sium Atlanta A ovember 1 8

atz SE eadache in iant Cell Arteritis: iagno-

sis and Management he eadache: 9 pdate

in iagnosis Management he hio tate ni-

versity Columbus ebruary 9

atz SE rbital iseases hio phthalmologi-

cal ociety () Annual Meeting Advanced ech-

nician session Columbus ebruary 1 9

atz SE Cummings: A mall-ye ainter

from ew ngland Anther Cummings: enre

and ntertext ymposium he Cummings o-

ciety at the American iterature Association Annual

Meeting Boston MA May 9

atz SE apilledema diopathic ntracranial yper-

tension and econdary seudotumor Cerebri

College of ptometry Columbus May 9 9

ingsbury cular Manifestations of ystemic

isease C ecture ast ospital Colum-

bus une 6 9

etson A iabetic etinopathy Medet1 (ational telecast program) March 6 9

ewis J Mahmoud AM Beran oberts C

Clinical Comparison between single- and dual-

FKHLPSXJNHUDWRPHWU\DQGSDFK\PHWU\DQGUH-

sponse to misalignment uropean ociety of Cata-

ract and efractive urgery (C) nternational

Meeting Berlin ermany eptember 15 8

ewis J Comparison of esponse to Misalignment

in achymetry Measurement Between ingle- and'XDOFKHLPSXJ'HYLFHV7KH$PHULFDQRFLHW\

of Cataract and efractive urgery Annual Meeting

(AC) an rancisco CA April 5 9

ewis J Mahmoud AM Beran oberts

C Comparison of esponse to Misalignment

in achymetry Measurement Between ingle- and

'XDOFKHLPSXJ'HYLFHV$PHULFDQ$VVRFLDWLRQ

of Cataract and efractive urgery (AC) Annual

Meeting an rancisco CA April 5 9

ewis J Meek M rgel nvestigation of i-

bril ltrastructure in ptic erve by -ay cattering

Association for ision and phthalmology (A) An-

nual Meeting t auderdale May 9

iu J Changes in Corneal Biomechanical roper-

ties after Corneal Collagen Crosslinking: etection

etection by ew mmersion ltrasonic evice

Association for ision and phthalmology (A)

Annual Meeting an rancisco CA Apr 6 9

27

Dr. Amit Tandon teaching residents

Ophthalmology Faculty

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Rebecca Kuennen, MDAnterior Segment

Julie Meier, MDComprehensive

Kelly Kingsbury, ODptometry

Ophthalmology Faculty

W. Randall McLaughlin, ODptometry

Elson Craig, MDathology

Matthew Dangel, MDAnterior Segment

David Castellano, MDefractive Surgery

Deborah Grzybowski, PhDesearch

Steven Katz, MDNeuro-phthalmology

David Hirsh, MDNeuro-phthalmology

Gloria Fleming, MDlaucoma

Cynthia Roberts, PhDesearch Amit Tandon, MDComprehensive Paul Weber, MDlaucoma

Thomas Mauger, MDAnterior Segment

Annette Terebuh, MDlaucoma

Susie Chang, MDetina

Carol Laxson, MD, PhDetina

John Christoforidis MDetina

Richard Lembach, MDAnterior Segment

Alan Letson, MDetina

Frederick Davidorf, MDetina

Colleen Cebulla, MD, PhDetina

Paul Kurz, MDetina

M. Iyad Azrak, MDlaucoma

Jun Liu, MDesearch

Ronald Xu, MDesearchMohammed Abdel-Rahman, MDesearch

This is a list of our full-time, onsite faculty. For a complete list of our faculty, visit www.eye.osu.edu/directory.

Ha ener E e Inst t te

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wwweyeosuedu

Havener Eye Institute

915 lentangy iver d uite 5

Columbus hio 431

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ostage

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Columbus hio

ermit o 11

avener Eye nstitute has witnessed amazing

developments in phthalmology since it was

established in 1929. The past 80 years have

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in the rest of human history. e are able to

to treat eye conditions and ocular diseases

that were unknown at the beginning of the

20th Century. ith each patient, we renew

our efforts to save sight and restore hope. e

believe that the contribution we make today

will echo forever in the lives of our patients.

OSUEye

&EarInst

itute