applications of mems in healthcare industry

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    by Rahul R. Raut Dessai,

    Goa College of Engineering.

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    The device comprises of three main units :

    i. Housing unit

    ii. Base unitiii. Sensing unit

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    The base unit is pivotally connected to the housing unit.

    The base unit includes electrical circuitry, a flexible ringand a receptacle.

    The sensing unit includes a pressure transducer, flexible

    diaphragm and interface layer.

    Non-invasive technique.

    Lifetime of 24 to 72 hrs.

    Annual production 17 million units per year, with a unitprice less than $10.

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    A conventional disc-type sensor can use only 10% of its total area for sensing.MEMS-based donut-type sensor can increase the sensing area to 50% of its total area.A conventional disc-type sensor can use only 10% of its total area for sensing.MEMS-based donut-type sensor can increase the sensing area to 50% of its total area.

    A conventional disc type sensor uses only 10 % of its total area for sensing.

    MEMS based donut type sensor can increase sensing area to 50 % of its totalarea.

    Sensing unit

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    HUMAN SKIN

    PRESSURE TRANSDUCER

    ELCETRICAL SIGNAL

    DISPLAY

    INTERFACE

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    Device that integrates one or several laboratory functionson a single chip.

    Scaling of single or multiple lab processes down to chip-format.

    Small size - millimeters to a few square centimeters.

    Small f luid volumes - less than Pico liters.

    Consists of mechanical flow control devices like pumpsand valves or sensors like flow meters and viscometers.

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    Basic fabrication processes is photolithography.

    Initially most processes were in silicon, as these well-developed technologies were directly derivedfrom semiconductor fabrication.

    Demands for specific optical characteristics, bio- orchemical compatibility, lower production costs and fasterprototyping increased.

    New processes have been developed such as glass, ceramicsand metal etching, deposition andbonding, PDMS processing (e.g., soft lithography), thick-film- and stereo lithography.

    Fast replication methods via electroplating, injectionmolding and embossing.

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    Low fluid volumes consumption .

    Faster analysis and less response time.

    Better process control.

    Compact systems.

    Lower fabrication costs.

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    Physical and chemical effects

    capillary forces,surface roughness, chemical interactions ofconstruction materials on reaction processes becomemore dominant on small-scale.

    Low signal to noise ratios - detection principles maynot always scale down in a positive way.

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    Real time polymerase chain reaction(PCR) - amplify asingle or a few copies of a piece of DNA.

    Biochemical assays - testing or measuring the activity ofa drug or biochemical in an organism or organic sample.

    Blood sample preparation - can lyse (break down) cells toextract DNA.

    Testing the safety and efficacy of new drugs.

    Glucose meter.

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