applications of mems in healthcare industry
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by Rahul R. Raut Dessai,
Goa College of Engineering.
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The device comprises of three main units :
i. Housing unit
ii. Base unitiii. Sensing unit
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The base unit is pivotally connected to the housing unit.
The base unit includes electrical circuitry, a flexible ringand a receptacle.
The sensing unit includes a pressure transducer, flexible
diaphragm and interface layer.
Non-invasive technique.
Lifetime of 24 to 72 hrs.
Annual production 17 million units per year, with a unitprice less than $10.
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A conventional disc-type sensor can use only 10% of its total area for sensing.MEMS-based donut-type sensor can increase the sensing area to 50% of its total area.A conventional disc-type sensor can use only 10% of its total area for sensing.MEMS-based donut-type sensor can increase the sensing area to 50% of its total area.
A conventional disc type sensor uses only 10 % of its total area for sensing.
MEMS based donut type sensor can increase sensing area to 50 % of its totalarea.
Sensing unit
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HUMAN SKIN
PRESSURE TRANSDUCER
ELCETRICAL SIGNAL
DISPLAY
INTERFACE
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Device that integrates one or several laboratory functionson a single chip.
Scaling of single or multiple lab processes down to chip-format.
Small size - millimeters to a few square centimeters.
Small f luid volumes - less than Pico liters.
Consists of mechanical flow control devices like pumpsand valves or sensors like flow meters and viscometers.
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Basic fabrication processes is photolithography.
Initially most processes were in silicon, as these well-developed technologies were directly derivedfrom semiconductor fabrication.
Demands for specific optical characteristics, bio- orchemical compatibility, lower production costs and fasterprototyping increased.
New processes have been developed such as glass, ceramicsand metal etching, deposition andbonding, PDMS processing (e.g., soft lithography), thick-film- and stereo lithography.
Fast replication methods via electroplating, injectionmolding and embossing.
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Low fluid volumes consumption .
Faster analysis and less response time.
Better process control.
Compact systems.
Lower fabrication costs.
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Physical and chemical effects
capillary forces,surface roughness, chemical interactions ofconstruction materials on reaction processes becomemore dominant on small-scale.
Low signal to noise ratios - detection principles maynot always scale down in a positive way.
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Real time polymerase chain reaction(PCR) - amplify asingle or a few copies of a piece of DNA.
Biochemical assays - testing or measuring the activity ofa drug or biochemical in an organism or organic sample.
Blood sample preparation - can lyse (break down) cells toextract DNA.
Testing the safety and efficacy of new drugs.
Glucose meter.
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