animal biotechnology course

Md. Najmul HossainBiotechnology & Genetic Engineering, UODA

ANIMAL BIOTECHNOLO

GY


Animal Biotechnology:Animal biotechnology is the use of science and engineering to modify living organisms.

The goal is to make products, to improve animals and to develop microorganisms for specific agricultural uses.

Examples: creating transgenic animals, using gene knock out or Knock in technology


Round Oak Rag Apple Elevation (born 1965)

1. >80,000 daughters,2. 2.3 million granddaughters, and 3. 6.5 million great-granddaughters

1944: 25.6 million animals; total annual milk production of 53.1 billion kg. 1997: 9.2 million animals; total annual milk production of 84.2 billion kg.

About half of this 369% increase in production efficiency is attributable to genetic improvement enabled by AI

Applications

http://www.google.com/url?sa=i&rct=j&q=Round+Oak+Rag+Apple+Elevation&source=images&cd=&cad=rja&docid=JInAKpO2pjjQLM&tbnid=jxWlrVL3-9iClM:&ved=0CAUQjRw&url=http://bullpages.selectsires.com/pages/webpagegen.dll?cmd=showPage&AniID=7HO58&lang=Eng&ei=9qJgUdzqIeGviQKq-oDIDg&psig=AFQjCNENnMcyBKBv7g96CVQKXw7_lBg24w&ust=1365374022498513


GE Chickens That Don't Transmit Bird FluBreakthrough could prevent future bird flu epidemics

Applications


OMEGA-3 PIGS(PIGS CLONED AFTER GENETICALLY ENGINEERING CELL)

Applications


FAST GROWING SALMONTHE FOUNDER FEMALE WAS GENERATED IN 1989 ~

Applications


Extent of use

Public and government acceptance

Current technical

capability for using

technology

Infrastructure and materials and tools available for using

technology

Relative cost

Skills required for application

Potential for generating

impact (time frame <10

years)

ARTIFICIAL INSEMINATION ++ +++ ++ ++ ++ ++ +++PROGESTERONE MONITORING + +++ + + ++ ++ ++ ESTRUS SYNCHRONIZATION + +++ + + ++ ++ ++

IN VITRO FERTILIZATION/ EMBRYO TRANSFER

+ +++ + + +++ +++ ++

MOLECULAR MARKERS + +++ + + ++ +++ +CRYOPRESERVATION + +++ ++ + ++ +++ ++SEMEN AND EMBRYO SEXING + +++ + + +++ ++ ++CLONING + + + + +++ +++ +TRANSGENESIS/GE 0 + + + +++ +++ +

Current status of animal biotechnologies and factors influencing their applicability in developing countries - GENETICS


The Technology Involved in ABT

•Transgenics (also known as recombinant DNA) Transgenic animals created by two methods

1. DNA microinjection2. Embryonic stem cells & gene knock-

outs/ also Cre-loxP

•Cloning•knock out technology

DNA microinjectionmethod


EDUCATIONAL ACTIVITYThinking Critically

1) Is it acceptable to create an animal that feels no pain through the use of animal biotechnology? Why or why not?

2) An animal has been used to create a promising new drug for the treatment of many types of cancer. However, the process involved might bring pain to the animal used to make the drug. Is this acceptable considering the end result? Why or why not?• Should we make the animal incapable of pain in this case? Why or

why not?


ETHICAL AND SOCIAL CONSIDERATIONS: “playing God”

Two main areas of debate:

1. Animal Welfare

2. Religious Issues

Course Outline Animal physiology and metabolism- an overview.

The principles of cell differentiation, growth and differentiation of blood cells, genetic control of muscle cell differentiation, potency of stem cells and prospects for medical uses.

Hormonal control of development.

Introduction to transgenic animals and overview of methodologies for nuclear transfer.


Thank You

&

Welcome to the world of Animal Biotechnology

animal biotechnology course

Education