plasma cell mucositis

Case Report

•A 47-year-old male patient

• Complains of burning sensation of mouth

•Duration-2 years

Chief Complaint

History of Presenting Illness

•History of diffuse large B cell lymphoma for which he underwent chemo and radiation therapy.

•He developed the present problem 3 months after the therapy.

•Numbness in the tongue.

Clinical Examination ExtraoralNo abnormality detected.IntraoralRevealed linear ulceration of size 2.5 x 1 cms covered by a yellowish white pseudomembrane on the buccal mucosa bilaterally at the level of the occlusal plane.

Right buccal mucosa

Provisional diagnosis:

• Erosive / Bullous lichen planus• Lichenoid reaction• Chronic ulcerative stomatitis• Chemotherapy induced oral mucositis

Histopathology

Superficial stratified squamous epithelium

(10x)

Histopathology

Sheets of plasmacytoid cells in the connective tissue40X

Histopathology

Cellular and nuclear pleomorphism

HISTOPATHOLOGY

Vesiculated and hyperchromatic nuclei

peripheral chromatin condensation

Immunohistochemistry Kappa and lambda

Kappa Lambda

Plasma cell mucositis / Chronic

ulcerative stomatitis

Plasma cell mucositis