outcome: meaningful (~30%) pain improvement...neuropathic pain: pharmacotherapy treatment outcome:...
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NeuropathicPain:PharmacotherapyTreatment
Outcome:Meaningful(~30%)PainImprovementOrderedbydecreasingestimatedefficacy
Limitations1. Basedonindirect
comparisons.2. Timeframe~4to
12weeks.3. Detailsonmethods
availableinonlinesupplement.
Amitriptyline
Venlafaxine
Gabapentin
Cannabinoids
25Improvewithtreatment
25Improvewithplaceboornotreatment
50Noimprovement
17Improvewithtreatment
25Improvewithplaceboornotreatment
58Noimprovement
15Improvewithtreatment
25Improvewithplaceboornotreatment
60Noimprovement
9Improvewithtreatment
25Improvewithplaceboornotreatment
66Noimprovement
HighDoseOpioids*
*60-110mgoralmorphineperday
Pregabalin
Duloxetine
18Improvewithtreatment
25Improvewithplaceboornotreatment
57Noimprovement
16Improvewithtreatment
25Improvewithplaceboornotreatment
59Noimprovement
13Improvewithtreatment
25Improvewithplaceboornotreatment
62Noimprovement
Improvewithtreatment
Improvewithplaceboornotreatment
Noimprovement
2018
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