~o}~lai ~b-~ visceral leishmaniasis · 2018. 10. 12. · 35 ±o}5'1jl} : al110 1'1 all...
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35
±o}5'1 Jl} : Al110 1'1 All 1:Q.. 2004\'! Vol. 10. No. 1. June 2004
~o}~lAi ~B-~ Visceral Leishmaniasis
Visceral Leishmaniasis in a Child
Hyun-Young Kim, MD., Seung-Eun Jung, MD., Kwi-Won Park, MD., Woo-Ki Kim, MD.
Department of Surgery, Seoul National University College of Medicine
Seoul, Korea
Visceral leishmaniasis is a life-threatening systemic infection caused by a protozoa of the genus leishmania and transmitted by sandfly. We report the first case of visceral leishmanaisis in Korea. The patient was a one-year-old girl admitted with the symptoms of fever,
abdominal distension, pancytopenia, and purpura. She traveled to Argentina 5 months ago, and has had symptoms such as fever and pale appearance. Laboratory findings were: WBC, 12,680/mm3 ; Hg, 3.7g/dL; platelet, lOOK; total bilirubin, 1.2mg/dL; AST/ALT, 48/10 U/L. CT scan
and MRI showed hepato-splenomegaly. On laparotomy, excision of an accessory spleen and splenic hilar lymph nodes were performed. Many amastigotes were microscopically identified in histiocytes from the biopsy tissues. Sodium stibogluconate was administrated for 2 weeks,
which did not relieve the symptoms. After administration of the additional Amphotericin B for 3 weeks. symptoms were improved. (J Kor Assoc Pediatr Surg lO(l)::1'5~38), 2004.
Index Words: Visceral leishmaniasis, Non-endemic areas, Child
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Correspondence: Kwi-Won Park, MD., Department of Surgery,
Seoul National University College of Medicine, 28 Yongon-dong,
Chongno-Gu, Seoul 110-744, Korea
Tel : 02) 760-3635, Fax: 02) 766-3975 E-mail: pedsurg@plaza.snu.ac.kr
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36
Fig. 1. Skin lesion: purpuric macular lesion abdominal wall(A), and face(8).
Fig. 2. Hepatosplenomegaly in CT image(A) and MRI image(8)
Fig. 3. Microscopic photography, showing the amastigotes in the celis: A, accessory spleen (Giemsa staining: x 400); 8, splenic hilar lymph node (Immunohistochemical staining: x 400).
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