nexo web poster for ismb 2014 biovis sig

Keiichiro Ono (kono@ucsd.edu)University of California, San Diego Department of Medicine

What is NeXO Web?

NeXO WebAn Integrated Ontology Visualization Application for Modern Web Platforms

Technologies

Gene Ontology Visualizations

Search & Term EnrichmentAnalysis Window

Ontology Tree (DAG) View

Raw Interaction View

Term Details

A gene ontology inferred from molecular networks. Janusz Dutkowski, Michael Kramer, Michal A Surma, Rama Balakrishnan, J Michael Cherry, Nevan J Krogan & Trey Ideker. Nature Biotechnology 31, 38–45 (2013).

NeXO (Network eXtracted Ontology) is a data-driven gene ontology inferred directly from ‘omics data. The NeXO Web application is designed to visualize the NeXO data sets and existing ontologies, such as GO, utilizing modern web technologies. - Provides a new way to visualize ontology data sets with modern web technologies - Integrate multi-omics data into a HTML5-based Single Page Application (SPA) - Open for future expansion

Theoritical BackgroundNeXO Web: the NeXO ontology database and visualization platform. Dut-kowski J, Ono K, Kramer M, Yu M, Pratt D, Demchak B, Ideker T. Nucleic Acids Res. 2014 Jan;42 (Database issue)

Thechnical Background

nexontology.org

sigma.jsClient-Side Server-Side

Cytoscape.js