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HOW DOES BLOOD CLOT

ROSHNI KULKARNI MDProfessor, Department of Pediatrics & Human Development, Michigan State University

USHA M REDDY MDVisiting Scholar, MSUMultimedia, Graphics, Webpage Consultant

BRUCE L EVATT MDDirector, Hematologic Disease Branch

Center for Disease Control (CDC)

HEMOSTASIS

• How does blood clot– Hemostasis overview– Platelet activation– Extrinsic pathway– Intrinsic pathway– Tissue factor pathway

• Platelet– Platelet Production– Platelet Membrane– Platelet Body– Platelet Granules– Platelet role in Hemostasis

HOW DOES BLOOD CLOT - OVERVIEW

PLATELET ACTIVATION

EXTRINSIC PATHWAY

INTRINSIC PATHWAY

TISSUE FACTOR PATHWAY

PLATELET

PLATELET PRODUCTION

THE PLATELET MEMBRANE

THE PLATELET BODY

THE PLATELET GRANULES

THE PLATELET ROLE IN HEMOSTASIS

END

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