from left to right: francois jacob (1920- ), jacques monod (1910-1976)
Post on 14-Jan-2016
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From left to right: Francois Jacob (1920- ), Jacques Monod (1910-1976) and André Lwoff (1902-1994), awarded the Nobel Prize for Physiology or Medicine in 1965. Jacques Monod was director of the Pasteur Institute in Paris from 1971 to 1976.
Element purpose
Operator (LacO) binding site for repressor
Promoter (LacP) binding site for RNA polymerase
Repressor (LacI)gene encoding lac repressor protein
Binds to DNA at operator and blocks binding of RNA polymerase at promoter
Pi promoter for LacI
CAP binding site for cAMP/CAP complex
http://vcell.ndsu.nodak.edu/animations/lacOperon/movie.htm
OperonLeaderLength
Sequence
trp 14 MKAIFVLKGWWRTS
pheA 16 MKHIPFFFAFFFTFP
his 16 MTRVQFKHHHHHHHPD
thr 21MKRISTTITTTITITTQNGAG
leu 28MSHIVRFTGLLLLNAFIVRGRPVGGIQH
ilv 32MTALLRVISLVVISVVVIIIPPCGAALGRGKA
http://employees.csbsju.edu/hjakubowski/classes/ch331/bcintro/list_of_figures.htm
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