cervical/vaginal cytology n. shayanfar md associate professor of pathology tehran university of...
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CERVICAL/VAGINAL CYTOLOGY
N. Shayanfar MD
Associate Professor of Pathology
Tehran University of Medical Sciences
INTRODUCTION&HISTORY
Dr.George N.Papanicolaou(1883-1962) Dr.Aurel A.Babes 1927 Dr.George Papanicolaou&Dr.Herbert
F.Traut 1943
Microscopic Anatomy
Vagina:Non-Keratinizing Stratified Squamous Cervix:
Ectocervix:Non-Keratinizing Stratified Sqamous
Endocervix:Tall Columnar Epithelium �ُSquamocolumnar Junction
Original
Transformation zone
ASSESSMENT OF QUALITY OF SMEARS
THE BETHESDA SYSTEM
Statement of specimen adequacy Epithelial cell abnormalities Others
ADEQUACY OF THE SPECIMEN
Satisfactory for evaluation
Unsatisfactory
Epithelial cell abnormalities
Low grade intraepithelial lesion(LSIL)
-CIN1(mild dysplasia) & HPV changes High grade intraepithelial lesion
-CIN2,CIN3,CIS(carcinoma insitu)
LSIL
LSIL,HPV changes
HSIL
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