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CERVICAL/VAGINAL CYTOLOGY N. Shayanfar MD Associate Professor of Pathology Tehran University of Medical Sciences

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Page 1: CERVICAL/VAGINAL CYTOLOGY N. Shayanfar MD Associate Professor of Pathology Tehran University of Medical Sciences

CERVICAL/VAGINAL CYTOLOGY

N. Shayanfar MD

Associate Professor of Pathology

Tehran University of Medical Sciences

Page 2: CERVICAL/VAGINAL CYTOLOGY N. Shayanfar MD Associate Professor of Pathology Tehran University of Medical Sciences

INTRODUCTION&HISTORY

Dr.George N.Papanicolaou(1883-1962) Dr.Aurel A.Babes 1927 Dr.George Papanicolaou&Dr.Herbert

F.Traut 1943

Page 3: CERVICAL/VAGINAL CYTOLOGY N. Shayanfar MD Associate Professor of Pathology Tehran University of Medical Sciences
Page 4: CERVICAL/VAGINAL CYTOLOGY N. Shayanfar MD Associate Professor of Pathology Tehran University of Medical Sciences
Page 5: CERVICAL/VAGINAL CYTOLOGY N. Shayanfar MD Associate Professor of Pathology Tehran University of Medical Sciences

Microscopic Anatomy

Vagina:Non-Keratinizing Stratified Squamous Cervix:

Ectocervix:Non-Keratinizing Stratified Sqamous

Endocervix:Tall Columnar Epithelium �ُSquamocolumnar Junction

Original

Transformation zone

Page 6: CERVICAL/VAGINAL CYTOLOGY N. Shayanfar MD Associate Professor of Pathology Tehran University of Medical Sciences
Page 7: CERVICAL/VAGINAL CYTOLOGY N. Shayanfar MD Associate Professor of Pathology Tehran University of Medical Sciences
Page 8: CERVICAL/VAGINAL CYTOLOGY N. Shayanfar MD Associate Professor of Pathology Tehran University of Medical Sciences
Page 9: CERVICAL/VAGINAL CYTOLOGY N. Shayanfar MD Associate Professor of Pathology Tehran University of Medical Sciences
Page 10: CERVICAL/VAGINAL CYTOLOGY N. Shayanfar MD Associate Professor of Pathology Tehran University of Medical Sciences
Page 11: CERVICAL/VAGINAL CYTOLOGY N. Shayanfar MD Associate Professor of Pathology Tehran University of Medical Sciences
Page 12: CERVICAL/VAGINAL CYTOLOGY N. Shayanfar MD Associate Professor of Pathology Tehran University of Medical Sciences

ASSESSMENT OF QUALITY OF SMEARS

Page 13: CERVICAL/VAGINAL CYTOLOGY N. Shayanfar MD Associate Professor of Pathology Tehran University of Medical Sciences

THE BETHESDA SYSTEM

Statement of specimen adequacy Epithelial cell abnormalities Others

Page 14: CERVICAL/VAGINAL CYTOLOGY N. Shayanfar MD Associate Professor of Pathology Tehran University of Medical Sciences

ADEQUACY OF THE SPECIMEN

Satisfactory for evaluation

Unsatisfactory

Page 15: CERVICAL/VAGINAL CYTOLOGY N. Shayanfar MD Associate Professor of Pathology Tehran University of Medical Sciences

Epithelial cell abnormalities

Low grade intraepithelial lesion(LSIL)

-CIN1(mild dysplasia) & HPV changes High grade intraepithelial lesion

-CIN2,CIN3,CIS(carcinoma insitu)

Page 16: CERVICAL/VAGINAL CYTOLOGY N. Shayanfar MD Associate Professor of Pathology Tehran University of Medical Sciences
Page 17: CERVICAL/VAGINAL CYTOLOGY N. Shayanfar MD Associate Professor of Pathology Tehran University of Medical Sciences
Page 18: CERVICAL/VAGINAL CYTOLOGY N. Shayanfar MD Associate Professor of Pathology Tehran University of Medical Sciences

LSIL

Page 19: CERVICAL/VAGINAL CYTOLOGY N. Shayanfar MD Associate Professor of Pathology Tehran University of Medical Sciences

LSIL,HPV changes

Page 20: CERVICAL/VAGINAL CYTOLOGY N. Shayanfar MD Associate Professor of Pathology Tehran University of Medical Sciences

HSIL


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