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Post on 03-Jul-2015
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Complete the sequence of DNA of the human genome
There are 35,000 human genes in our genome
The method at use in this project is called a hierarchical shotgun
There are 7 main steps to the method
Break down into a code of 150,000 letters
Each fragment was placed into a bacterial artificial chromosome
The E. coli inside the chromosome would replicate each DNA sample
Special enzymes were used to cut each clone into ‘fingerprint’ of fragments
Combined the clones into a longer strand
Mapped them onto the human chromosome
Broke down the cloned fragments into 1000-2000 based pairs long
Generated a sequence of the individual bases
Shotgun method was used to sequence the fragments of human DNA
Overlaps of the letters of the genetic code were used to assemble the sequence of DNA
The first major experiment to map the human genome is performed on a sheep named Dolly
Deeper concepts were found in this experiment
Map out the single gene that causes genetic diseases or disorders
Discoveries in the medical fields
Cures of diseases
Costs 3 billion dollars
High risk in the project
People will not got a chance to live there lives fairly
DNA is going to determine the opportunities
Someday will be able to tell the life someone is going to live by there human genome
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