becoming a pi – how do i get from here to there? philip norris bsri
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Becoming a PI –How do I get from here to there?
Philip NorrisPhilip Norris
BSRI
Success rates for R01 grants
0%
10%
20%
30%
40%
2001
2002
2003
2004
2005
2006
2007
2008
2009
2010
NIAID R01 success rates
New R01 (all NIH)
http://report.nih.gov/success_rates/index.aspx
Funding by submission #
0% 10% 20% 30% 40% 50%
SecondResubmission (A2)
First Resubmission(A1)
First (Original)Submission
http://report.nih.gov/success_rates/index.aspx
Average Age of New Investigators at Initial R01 Equivalent award
34
36
38
40
42
44
19
70
19
71
19
72
19
73
19
74
19
75
19
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19
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19
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19
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95
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96
19
97
19
98
19
99
20
00
20
01
20
02
20
03
20
04
MDMD-PhD
PhD
http://grants.nih.gov/grants/new_investigators/Average_age_initial_R01.xls
Case study of a PI start-up
PI support
$-
$50,000
$100,000
$150,000
$200,000
$250,000
2004 2005 2006
PI direct
PI indirect
PI total
Grant applications
0
1
2
3
4
5
6
2004 2005 2006
PI
Total
Publications during start-up
0
1
2
3
4
5
6
2004 2005 2006
First/last author
Total
Collaboration can save lives
Overall support increasing in spite of decreased PI awards
$-
$200,000
$400,000
$600,000
$800,000
2004 2005 2006
Overall direct
Overall indirect
Overall total
$-
$50,000
$100,000
$150,000
$200,000
$250,000
2004 2005 2006
PI direct
PI indirect
PI total
PI funding Total funding
Keep trying!
Grant applications
0
4
8
12
2004 2005 2006 2007 2008 2009
PI
Total
Extramural supportPI funding
$-
$400,000
$800,000
$1,200,000
$1,600,000
$2,000,000
2004
2005
2006
2007
2008
2009
2010
pro
jecte
d
PI direct
PI indirect
PI total
Extramural supportTotal
$-
$400,000
$800,000
$1,200,000
$1,600,000
$2,000,000
2004
2005
2006
2007
2008
2009
2010
pro
jecte
d
Overall direct
Overall indirect
Overall total
Publications
0
4
8
12
2004 2005 2006 2007 2008 2009 2010
First/last author
Total
Don’t spread yourself too thin
Diverse projects and funding streams
Funding sources HIVHIV -- CHAVI, CFAR,
WIHS WNV – NHLBI / NIAID MicrochimerismMicrochimerism – NHLBI TRALI – REDS /
SCCOR Pathogen reduction –
DOD / Industry Transfusion immunology
–NHLBI / DOD
HIV Immunology Immune correlates of protection Early HIV/SIV immunity
WNV Immunology CD4+ T cell epitope definition Treg quantification
Transfusion Immunology Defining immunology of
microchimerism Immune responses to transfusion TRALI / HLA antibody quantification Pathogen reduction effects on WBCs
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