a potent and selective nonpeptide antagonist of the melanocortin-4 receptor induces food intake in...
Post on 06-Jun-2016
217 Views
Preview:
TRANSCRIPT
2005
Receptor binding activityX 0280 A Potent and Selective Nonpeptide Antagonist of the Melanocortin-4 Receptor In-
duces Food Intake in Satiated Mice. — Compound (I) is reported to show the stron-gest antagonistic activity and highest selectivity towards the targeted receptor of all tested compounds. — (CHEN*, C.; et al.; Bioorg. Med. Chem. Lett. 15 (2005) 10, 2541-2546; Dep. Med. Chem., Neurocrine Biosci., Inc., San Diego, CA 92121, USA; Eng.) — C. Oppel
39- 215
top related