a framework for diagnosing and treating cteph

A Framework for Diagnosing and Treating CTEPH

Program Goals

Pulmonary Embolism and CTEPH

CTEPH Mortality

CTEPH Risk Factors

Autopsy Findings

Case Presentation

Case Presentation (cont)

Case Presentation (cont)

Case Presentation (cont)

Case Presentation (cont)

Echocardiographic Findings

The Patient’s Echocardiogram

Ventilation-Perfusion Scan

Differential Diagnosis of Major Vessel Pulmonary Vascular Disease

Differential Diagnosis (cont)

CT Angiography: CTEPH

CT Angiogram: CTEPH (cont)

CT Angiogram of the Pulmonary Arteries: CTEPH

CT Angiogram (cont)

Right Pulmonary Artery Angiogram

Left Pulmonary Artery Angiogram

Right-Heart Catheterization Data

Right-Heart Catheterization Data (cont)

Main Principles of Surgery for CTEPH

Main Principles of Surgery for CTEPH (cont)

Thromboendarterectomy Specimen

Factors That Affect Decisions About Operability

How Do We Treat Inoperable CTEPH or Persistent PH After Pulmonary Endarterectomy?

Treating Inoperable CTEPH or Persistent PH After Pulmonary

Endarterectomy (cont)

Targets for Current Therapies in PAH

Bosentan in CTEPH (BENEFIT)

Riociguat for the Treatment of CTEPH (CHEST-1)

Methods

Riociguat for CTEPH Secondary Endpoints

Riociguat for CTEPHSecondary Endpoints (cont)

Summary

Abbreviations

Abbreviations (cont)

References

References (cont)

References (cont)