ISSN 0036-807519 JULY 1996VOLUME 273NUMBER 5273 S

AMERICANAssoCIATION FORTHEADVANCEMENT OFSCIENCE

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307 -Atoms at the quantumedge

335 -wSimulating planetaryatmospheres

AAAS BoardRita R. ColwellRetiring President, Chairman

Jane LubchencoPresident

Mildred S. DresselhausPresident-elect

NEWS & COMMENTBiotech Finds a Growth Industry

AIDS Conference: Chemokines ShareCenter Stage With Drug TherapiesShooting for the Moon With Drugs

1997 Budget: Congress Targets Fusion,Favors NIH

Electronic Publishing: APS StartsElectronic Preprint Service

German Research Budget: Less Money,But Much Needed Reform

Xenotransplants: IOM Backs CautiousExperimentation

Particle Physics: Upgraded LEPBags First W Pairs

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RESEARCH NEWSGiant Atoms Cast Long Shadow

Developmental Biology: Receptor forVital Protein Finally Found

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THIS WEEK IN SCIENCE

EDITORIALRoads Not Taken, YetR. Roy

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LETTERS 293Acid Rain Revisited?: C. R. Frink; J. W. Kirchner;G. E. Likens, C. T. Driscoll, D. C. Buso * Herbivoryin Soft Corals: Correction: K. Fabricius, Y. Benayahu,G. Yahel, A. Genine Diffusion to a Different Drum-mer: M. F. Schumaker * Extinction Rates: J. L. Simon;S. L. Pimm, J. L. Gittleman, G. J. Russell, T. M. Brooks

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Plant Biochemistry: Mutant rAlga Blurs Classic Pictureof Photosynthesis

Galileo Finds Mysterious MagneticField at Ganymede

Materials Science: Throwing-orMolding-a Curve Into Nanofabrication

RANDOM SAMPLES 313Sex and Olfaction * Berkeley Chancellor Plansto Move On * Invulnerable Vole Found at Cher-nobyl * Making Molds for Plastic Antibodies *

Harvard and China Probe Disease Genes * KobeEarthquake Continues to Rattle Walls * "Sociobi-ology" to History's Dustbin?

BOOK REVIEWS 316Creative Couples in the Sciences, reviewed by R. L.Sime * Genomic Imprinting, C. Sapienza * Vignettes* Books Received

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DirectorsSheila JasanoffWilliam A. Lester Jr.Simon A. LevinMarcia C. LinnMichael J. NovacekAnna C. RooseveltJean E. TaylorNancy S. Wexler

William T. GoldenTreasurer

Richard S. NicholsonExecutive Officer

* SCIENCE (ISSN 0036-8075) Is published weekly on Friday, except the last week InDecember, by the American Association for the Advancement of Science, 1200 New YorkAvenue, NW, Washington, DC 20005. Periodicals Mail postage (publication No. 484460) paid atWashington, DC, and additional mailing offices. Copyright 1996 by the American Association forthe Advancement of Science. The title SCIENCE is a registered trademark of the AAAS. Domesticindividual membership and subscription (51 issues): $102 ($55 allocated to subscription). Domesticinstitutional subscription (51 issues): $250. Foreign postage extra: Mexico, Caribbean (surface mail)$55; other countries (air assist delivery) $90. First class, airmail, student, and emeritus rates onrequest. Canadian rates with GST available upon request, GST #1 254 88122. Printed In the U.S.A.

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POLICY FORUM

Psychiatric Drug Developmentin JapanD. Berger and I. Fukunishi

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PERSPECTIVESAtmospheric Dynamics on theOuter PlanetsP. J. Gierasch

Cuprates Fall into a GapN. P. Ong

Mechanosensation and theDEG/ENaC Ion ChannelsD. P. Corey and J. Garcia-Afioveros

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SCIENCE * VOL. 273 * 19 JULY 1996

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Endocytic compartment (-600 nanometers in diameter) ofa human mononuclear phagocyte revealed by electronmicroscopy of thin cryosections. Major histocompatibilitycomplex (MHC) class 11 molecules accumulate in thesemultilaminar compartments, which may be the major sites

RESEARCH ARTICLE

Excitation Gap in the Normal State r 325of Underdoped Bi,SrnCaCu,O5,6A. G. Loeser, Z.-X. Shen, D. S. Dessalu, D. S.M irshall, C. H. Pairk, P'. Fournier, A. Kapitulnik

REPORTS

Role of Lipid Polymorphism in 330Pulmonary SurfactantW. R. Perkins, R. B. DaIuse, R. A. Parente, S.R. Minchev, K. (C. NeuTman, S. M. Gruner, T.F. Taraschi, A. S. Janftd

Hydrogen-Bond Breaking and ProtonExchange in Collisions of Gaseous FormicAcid with Liquid Sulfuric Acid

3. K. Klassen and C. NI. Nathanson

The Morphogenesis of Bands andZonal Winds in the Atmospheres onthe Giant Outer Planets

J. Y.-K. Cho and L. NM. Polvani

CCOVER

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A Magnetic Signature at lo: Initial 337Report from the Galileo Magnetometer

NX. C. Kivelson, K. K. KhuLrana, R. J. Walker,(C. T. RuLssell, J. A. L,inker, D. J. Southwood, C.POaIonskevI

Detection of Ozone on Ganymede 341K. S. Noll, R. E. Johnlson, A. L. Lane, D. L.Po(milngLe, H. A. Weaver

Self-Assembled Smectic Phases in 343Rod-Coil Block Copolymers

J. T. Chen, E. L. Thiomams, (C. K. Oher, G.-P. Mao

Complex Optical Surfaces Formed by 347Replica Molding Against Elastomeric MastersY. Xia, E. Kimn, X.-M. Zhao, J. A. Rogers, M.Prentiss, C. M. Whitesides

Cytoplasmic Tail-I)ependent 349Localization of CDlb Antigen-PresentingMolecules to MIICsM. Sugita, R. M. Jackiman, E. van Ponselaar, S.M. Behar, R. A. Rogers, P. J. Peters, M. B.Breinner, S. A. Porcelli

where endocytosed protein antigens are encountered.CD1 b (smaller, black-stained dots), a non-MHC-encodedmolecule that presents bacterial lipid antigens to T cells,also localizes to these compartments. See page 349. [Image:P. J. Peters, E. van Donselaar, M. Sugita, and S. A. Porcelli]

352

367Bewarefeeding fleas

370Peptide signals in plants

Immunostimulatory DNA SequencesNecessary for Effective IntradermalGene ImmunizationY. Sato, M. Roman, H. Tighe, D. Lee, M. Corr,M.-D. Nguyen, G. J. Silverman, M. Lotz, D. A.Carson, E. Raz

The Secreted Product of XenopusGene lunatic Fringe, a VertebrateSignaling Molecule

J. Y. Wu, L. Wen, W.-J. Zhang, Y. Rao

Resistance to Apoptosis Conferredby Cdk Inhibitors During MyocyteDifferentiation

J. Wang and K. Walsh

Interaction Between a PutativeMechanosensory Membrane Channeland a Collagen

J. Liu, B. Schrank, R. H. Waterston

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Oxygenic Photoautotrophic Growth 59 364Without Photosystem I

J. W. Lee, C. V. Tevault, T. G. Owens, E.Greenbaum

Role of the Yersinia pestis Hemin 367Storage (hms) Locus in the Transmissionof Plague by FleasB. J. Hinnebusch, R. D. Perry, T. G. Schwan

Modification of Phytohormone 370Response by a Peptide Encoded byENOD40 of Legumes and a NonlegumeK. van de Sande, K. Pawlowski, I. Czaja, U.Wieneke, J. Schell, J. Schmidt, R. Walden, M.Matvienko, J. Wellink, A. van Kammen, H.Franssen, T. Bisseling

r Indicates accompanying featureChange of address: allow 4 weeks, giving old and new addresses and 8-digit account number.Postmaster: Send change of address to Science, P.O. Box 1811, Danbury, CT 06813-1811.Single copy sales: $7.00 per issue prepaid includes surface postage; bulk rates on request.Authorization to photocopy material for internal or personal use under circumstances not fallingwithin the fair use provisions of the Copyright Act is granted by AAAS to libraries and other usersregistered with the Copyright Clearance Center (CCC) Transactional Reporting Service, providedthat $4.00 per article is paid directly to CCC, 222 Rosewood Drive, Danvers, MA 01923. Theidentification code for Science is 0036-8075/83 $4.00. Science is indexed in the Reader's Guide toPeriodical Literature and in several specialized indexes.

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