a patient with chest pain and st-elevation in avr and st ... · a patient with chest pain and...

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A patient with chest pain and ST-elevation in aVR and ST depression in all other leads ACCA Masterclass 2017 Sofie Gevaert

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A patient with chest pain and ST-elevation in aVR and ST depression in all other leads

ACCA Masterclass 2017

Sofie Gevaert

Mr LP, 55-years-old

• History:

• Hypertension, treated with Perindopril 5mg and Nebivolol 5mg

• Current:

• 01.00 am: progressive severe thoracic pain radiating to left arm

• Orthopnoea

• 112Medical emergency team

• Other CV risk factors:

• Hyperlipidaemia

• Obesity

• Sudden death of father at 50 y

ACCA Masterclass 2017

MET 08.00 am: parameters, clinical exam

• BP 142/72 mmHg, HR 160 bpm, regular, SaO2 88%, Resp R 27/min

• Clammy, cold extremities

• No jugular distension

• No cardiac murmur

• Bilateral crepitations

• No peripheral edema

ACCA Masterclass 2017

ACCA Masterclass 2017

FMC in patient with chest pain

ACCA toolkit 2015

ECG 08.05 am

ACCA Masterclass 2017

ACCA Masterclass 2017

1. ER: Patient with chest pain, 08.28 am

ACCA toolkit 2015

Further strategy?

• Further stabilisation, diagnostics in ER?

• Direct transfer to cathlab?

ACCA Masterclass 2017

2. ER: dyspnoea, orthopnoea

ACCA Masterclass 2017ACCA toolkit 2015

Chest X-ray 08.32 am

ACCA Masterclass 2017

Furosemide 40mg IV (MET)

Quick look echo

ACCA Masterclass 2017

?

ACCA toolkit 2015

ACCA Masterclass 2017

CONGESTION - +

HYPO _PERFU S +IOn

ESC guidelines AHF 2015

ACCA Masterclass 2017ACCA toolkit 2015

08.45 am

• Ongoing chest pain despite high dose opioids

• SaO2 90 despite FiO2 90%

• Persisting respiratory failure despite initial measures

• Troponin T 435 ng/L, creatinine 2.1 mg/dL (CKD-EPI 30 mL/min), Hct 42%

• PH 7.24, PCO2 47mmHg, lactate 34.1 mg/dL (<11.3 mg/dL, =3.8mmol/L)

ACCA Masterclass 2017Sedation, Intubation

Invasive strategy: Timing, antithrombotic R/ andaccess

• Timing?• Antiplatelet?

• None

• ASA mono

• DAPT

• Anticoagulation?• None

• UFH

• LMWH

• Fondaparinux

• Bivalirudin

• Access?

ACCA Masterclass 2017

ACCA Masterclass 2017ACCA toolkit-ESC guidelines NSTE-ACS2015

Timing

ACCA Masterclass 2017ACCA toolkit 2015

Ischemic risk

ACCA Masterclass 2017

Bleeding risk

ACCA Masterclass 2017

High ischemic and high bleeding riskKD and shock state

UFH 5000 IU bolus

ASA 200mg IV

ACCA Masterclass 2017ESC guidelines NSTE-ACS 2015

Coronary angiography 09.20 am

ACCA Masterclass 2017

Shock, peripheral VC:Femoral access

ACCA Masterclass 2017

CT angiography 09.50 am

ESC guidelines Aortic dis. 2014

Type A dissection with dissection left main

• Urgent surgery

• Tear ascending aorta

• Urgent surgery:Hemiarch

Sinotubular junction proximal arch

• Postoperative: stroke, AKI

• Rehab program

ACCA Masterclass 2017

THANK YOU

ACCA Masterclass 2017

Sofie Gevaert