a designer amphetamine that has become one of the most widely abused drugs in the adolescents a...
TRANSCRIPT
A designer amphetamine that has become one of the most widely abused drugs in the adolescents
A blending of sympathomimetic amphetamine stimulation with the hallucinogenic effects of mescaline
The drug is popular at “rave “ parties and at dance clubs. Following ingestion, the onset of action is 30 – to 90
minutes, plateau effects are achieved in 2- 3 hours The drug is abused because it induces extreme
euphoria, increased energy, feeling of belongings, heightened sensations, empathy, music appreciation
(3,4,methylenedioxymethamphetamine) Ecstasy
Toxic effects & Major complications Bruxism Trismus Short-term memory loss Confusion Headches Vertigo Ataxia Vomiting Depression&psychological
addiction
Profound hyperthermia Hypertension Seizures Dehydration Hyponatremi Hepatic and renal failure Rhabdomyolysis MI & ICH
Psychological
Euphoria Closeness to others love drug Serotonergic properties Shimmering visual effects
Differential Diagnosis
Amphetamines LSD Phencyclidine abuse
Management
Supportive care, airway management, rapid cooling
Liberal doses of benzodiazepines for tachycardia,hypertension, and agitation
Activated charcoal Toxicology urine screens that are marketed to
detect amphetamines can be negative after ecstacy and desighner amphetamine use
Fluid
Management
Consultation with a local or regional poison center Observation for4 to 6 hours Because of 10 -50% repeat ingestion, families must
be received a kind of instuction about poison prevention
Admission to the hospital(slow release substances and or ingestion of significant amounts of drug
A conservative approach for toxins that can cause potential mortality in small doses (camphor, benzocaine, lomotil, chloroquin, methyl salicylate
All patients with intentional overdoses should undergo psychiatric assessment