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BARCELONA, September 14 th -16 th , 2017 SYMPOSIUM VENUE: UNIVERSITAT DE BARCELONA – PARANIMF PRESIDENTS Antonio Montero, Carmelo Scarpignato, Giustino Varrassi SCIENTIFIC PROGRAMME Promoted by PAIN MANAGEMENT UNMET NEEDS IN ACUTE PAIN BRIDGING MENARINI FOUNDATION TO PAIN MEDICINE

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BARCELONA, September 14th-16th, 2017SYMPOSIUM VENUE: UNIVERSITAT DE BARCELONA – PARANIMF

PRESIDENTS Antonio Montero, Carmelo Scarpignato, Giustino Varrassi

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Promoted by

PAIN MANAGEMENTUNMET NEEDS IN ACUTE PAIN

BRIDGING MENARINI FOUNDATION

TO PAIN MEDICINE

PRESIDENTS Antonio Montero, Carmelo Scarpignato, Giustino Varrassi2

BARCELONA, September 14th-16th, 2017SYMPOSIUM VENUE: UNIVERSITAT DE BARCELONA – PARANIMF

PAIN MANAGEMENTUNMET NEEDS IN ACUTE PAIN

SECOND JOINT MENARINI INTERNATIONAL FOUNDATION/EULAP SYMPOSIUM

The fi rst edition of this scientifi c event has been – everybody agreed – an overwhelming success. Over 400 delegates were already pre-registered, but by the date of the Opening Ceremony in Budapest (13th of October 2016) the number exceeded 500 attendants, willing to enjoy the extremely high level scientifi c discussion on Pain Medicine, held during the three days of the Symposium.

This was the main reason why we decided to organize a second edition, this time in Barcelona. It will be a fantastic occasion to discuss one of the most interesting aspects of pain medicine, i.e. Acute Pain. This event will be a very interesting one and will certainly shed light on the current management of acute pain, highlighting the unmet needs still present in the third millennium.

As customary, the Faculty will gather topfl ight experts in the fi eld. In particular, the opening lecture, devoted to the one of the great dilemmas of pain mechanisms, Bioethics in Acute Pain, will be delivered by Professor Jaime Boceta, universally considered the world number one in this topic. The current knowledge about acute pain will be then presented by outstanding speakers, who will give the background to focus on post-operative pain, the most frequent problems in pain medicine. Established and new therapeutic approaches, from the multi-modal analgesia to the “futuristic” therapeutic approaches like the “fast-track analgesia” or the “procedure-specifi c analgesia”, will complete the picture.

We do hope to see you all in Barcelona, but also expect that you will become addicted to the high scientifi c level of these events. Your enthusiastic attendance will guarantee a large diffusion of the knowledge delivered at the Symposium and represent the best reword for the organizers. Our common efforts will certainly contribute to relieve suffering and induce wellbeing of the many pain patients worldwide.

Antonio Montero Carmelo Scarpignato Giustino Varrassi

PRESIDENTS Antonio Montero, Carmelo Scarpignato, Giustino Varrassi 3

BARCELONA, September 14th-16th, 2017SYMPOSIUM VENUE: UNIVERSITAT DE BARCELONA – PARANIMF

PAIN MANAGEMENTUNMET NEEDS IN ACUTE PAIN

PRESIDENTS

Antonio Montero, MD

Professor of Anesthesiology and Pain Management, University of Lleida, SpainDirector, Deparment of Anesthesiology, Intensive Care and Pain Management,Hospital Universitario Arnau de Vilanova, Lleida, Spain

Carmelo Scarpignato, MD, DSc, PharmD, MPH, FRCP (London), FACP, FCP, FACG, AGAF

Professor of Clinical Pharmacology, University of Parma, ItalyAssociate Professor of Gastroenterology, University of Nantes, FranceGeneral Secretary, World Organization for Esophageal Diseases (OESO), Paris, FranceGovernor for Italy, American College of Gastroenterology (AGA)

Giustino Varrassi, MD, PhD, FIPP

President, Paolo Procacci Foundation (PPF)President, European League Against Pain (EuLAP)President-Elect, WIPRome, Italy

SCIENTIFIC SECRETARIAT AND ORGANIZING COMMITTEE

Anna Bertelé, MD

Clinical Pharmacology & Digestive Pathophysiology Unit Department of Clinical & Experimental Pharmacology University of Parma, Italy E-mail: [email protected]

Antonella Paladini, MD, PhD

Anesthesiology & Pain MedicineDepartment of Clinical Medicine, Public Health & Health SciencesUniversity of L’Aquila, ItalyE-mail: [email protected]

Scientifi c coordination byASSOCI

AZIONE

ITALIANA PER LO STUDIO DEL DOLORE

AISD

UNDER THE AUSPICES OF:

Spanish Pain Society

Catalan Pain Society

Spanish Society of Anaesthesiology, Resuscitation and Pain Relief

Italian Association forthe Study of Pain (AISD)

Paolo Procacci Foundation

PRESIDENTS Antonio Montero, Carmelo Scarpignato, Giustino Varrassi4

BARCELONA, September 14th-16th, 2017SYMPOSIUM VENUE: UNIVERSITAT DE BARCELONA – PARANIMF

PAIN MANAGEMENTUNMET NEEDS IN ACUTE PAIN

SCIENTIFIC PROGRAM COMMITTEE

José Luis Aguilar (Palma, Spain)

Eli Alon (Zurich, Switzerland)

Caterina Aurilio (Naples, Italy)

Corrado Blandizzi (Pisa, Italy)

Elena Catalá (Barcelona, Spain)

Stefano Coaccioli (Perugia, Italy)

Antonio Corcione (Naples, Italy)

Francesco Di Mario (Parma, Italy)

Juan Carlos Flores (Buenos Aires, Argentina)

Victor Mayoral (Barcelona, Spain)

Antonio Montes (Barcelona, Spain)

Marco A. Narvaez Tamayo (La Paz, Bolivia)

Vincenzo Piras (Cagliari, Italy)

Ricardo Plancarte (San Nicolás, Mexico)

Luigi Fabrizio Rodella (Brescia, Italy)

Stephan Schug (Perth, WA, Australia)

Rosalba Tufano (Naples, Italy)

Athina Vadalouka (Athens, Greece)

FACULTY

José Luis Aguilar (Palma, Spain)

Eli Alon (Zurich, Switzerland)

Caterina Aurilio (Naples, Italy)

Corrado Blandizzi (Pisa, Italy)

Jaime Boceta (Sevilla, Spain)

Candela Calle (Barcelona, Spain)

Elena Catalá (Barcelona, Spain)

Stefano Coaccioli (Perugia, Italy)

Asbjørn Mohr Drewes (Copenhagen, Denmark)

Juan Carlos Flores (Buenos Aires, Argentina)

Giandomenico Iannetti (London, UK)

Alan D. Kaye (New Orleans, LA, USA)

Martin Koltzenburg (London, UK)

Rudolf Likar (Klagenfurt, Austria)

Francisco Macule (Barcelona, Spain)

Marco Abraham Marcus (Doha, Qatar)

César Margarit (Alicante, Spain)

Victor Mayoral (Barcelona, Spain)

Francisco Javier Medel (Barcelona, Spain)

Antonio Montero (Lleida, Spain)

Jordi Montero (Barcelona, Spain)

Antonio Montes (Barcelona, Spain)

Marco A. Narvaez Tamayo (La Paz, Bolivia)

Mercé Pallàs (Barcelona, Spain)

Marco Pappagallo (New York, NY, USA)

Ricardo Plancarte (San Nicolás, Mexico)

Gisela Roca (Badalona, Spain)

Daniel Samper (Badalona, Spain)

Carmelo Scarpignato (Parma, Italy)

Stephan Schug (Perth, WA, Australia)

Knox H. Todd (Mendoza, Argentina)

Carlos Tornero (Valencia, Spain)

Rosalba Tufano (Naples, Italy)

Athina Vadalouka (Athens, Greece)

Giustino Varrassi (Rome, Italy)

Xavier Vila (Lleida, Spain)

John Zeppetella (Hastingwood, UK)

PRESIDENTS Antonio Montero, Carmelo Scarpignato, Giustino Varrassi 5

PAIN MANAGEMENTUNMET NEEDS IN ACUTE PAIN

BARCELONA, September 14th-16th, 2017SYMPOSIUM VENUE: UNIVERSITAT DE BARCELONA – PARANIMF

THURSDAY, September 14th, 2017

09:00 a.m. Registration of the Delegates

POST-GRADUATE COURSE – PART I

ACUTE POSTOPERATIVE PAIN (APP) – STRATEGIES FOR MANAGEMENT

10:45 a.m. Presentation of the Course Antonio Montero (Lleida, Spain) – Giustino Varrassi (Rome, Italy)

GENERAL ASPECTS

11:00 a.m. APP: Novelties in Physiopathology José Luis Aguilar (Palma, Spain)

11:30 a.m. Clinical Features and Prevalence: (Ambulatory Surgery, Emergency Dpt., Wards...) Daniel Samper (Badalona, Spain)

12:00 p.m. Chronifi cation of APP. Prevention and Prevalence Following Different Surgical Procedures Antonio Montes (Barcelona, Spain)

12:30 p.m. APP in the Elderly: Novelties and Precautions Gisela Roca (Badalona, Spain)

01:00 p.m. Lunch

MANAGEMENT

02:00 p.m. APP Teams and Programs: Different Models and Adaptation to Hospital Environment. Measure of Results and Indicators Francisco Javier Medel (Barcelona, Spain)

02:30 p.m. Global Strategies of Treatment in APP Xavier Vila (Lleida, Spain)

03:00 p.m. Paracetamol and NSAIDs Carmelo Scarpignato (Parma, Italy)

03:30 p.m. Opioids Stephan Schug (Perth, WA, Australia)

04:00 p.m. Adjuvants Marco Pappagallo (New York, NY, USA)

PRESIDENTS Antonio Montero, Carmelo Scarpignato, Giustino Varrassi6

BARCELONA, September 14th-16th, 2017SYMPOSIUM VENUE: UNIVERSITAT DE BARCELONA – PARANIMF

PAIN MANAGEMENTUNMET NEEDS IN ACUTE PAIN

OPENING CEREMONY

06:00 p.m. Welcome Addresses • President of Fondazione Internazionale Menarini Alessandro Casini (Florence, Italy)

• Vicerector of the University of Barcelona Mercé Pallàs (Barcelona, Spain)

• Director of the Catalan Institute of Health Candela Calle (Barcelona, Spain) • Symposium Presidents: Antonio Montero (Lleida, Spain),

Carmelo Scarpignato (Parma, Italy), Giustino Varrassi (Rome, Italy)

06:30 p.m. Opening Lecture Bioethics in Acute Pain Jaime Boceta (Sevilla, Spain)

07:15 p.m. Welcome Cocktail

FRIDAY, September 15th, 2017

SYMPOSIUMPAIN MANAGEMENT – UNMET NEEDS IN ACUTE PAIN

SESSION I: WHAT WE KNOW ABOUT ACUTE PAINChairpersons: Victor Mayoral (Barcelona, Spain) – Eli Alon (Zurich, Switzerland)

09:00 a.m. Pain in the Emergency Department Knox H. Todd (Mendoza, Argentina)

09:30 a.m. Acute Visceral Pain Asbjørn Mohr Drewes (Copenhagen, Denmark)

10:00 a.m. Acute and Breakthrough Pain in Cancer Patients John Zeppetella (Hastingwood, UK)

10:30 a.m. Discussion

11:00 a.m. Coffee Break

PRESIDENTS Antonio Montero, Carmelo Scarpignato, Giustino Varrassi 7

PAIN MANAGEMENTUNMET NEEDS IN ACUTE PAIN

BARCELONA, September 14th-16th, 2017SYMPOSIUM VENUE: UNIVERSITAT DE BARCELONA – PARANIMF

SESSION II: WHAT WE KNOW ABOUT ACUTE PAINChairpersons: Juan Carlos Flores (Buenos Aires, Argentina) – Caterina Aurilio (Naples, Italy)

11:30 a.m. Spontaneous and Evoked Pain: Clinical Relevance for Acute Pain Conditions Jordi Montero (Barcelona, Spain)

12:00 p.m. Cortical Mechanisms of Nociception in Acute Pain Giandomenico Iannetti (London, UK)

12:30 p.m. Infl ammatory Pain: Mechanisms and Consequences Stefano Coaccioli (Perugia, Italy)

01:00 p.m. Discussion

01:30 p.m. Lunch

SESSION III: POST-OPERATIVE PAINChairpersons: José Luis Aguilar (Palma, Spain)

Marco A. Narvaez Tamayo (La Paz, Bolivia)

02:30 p.m. Post-Operative Pain in Europe Elena Catalá (Barcelona, Spain)

03:00 p.m. How is Incisional Pain Different? José Luis Aguilar (Palma, Spain)

03:30 p.m. Pain and Outcome After Orthopedic and Trauma Surgery Marco Abraham Marcus (Doha, Qatar)

04:00 p.m. Discussion

04:30 p.m. Coffee Break

PRESIDENTS Antonio Montero, Carmelo Scarpignato, Giustino Varrassi8

BARCELONA, September 14th-16th, 2017SYMPOSIUM VENUE: UNIVERSITAT DE BARCELONA – PARANIMF

PAIN MANAGEMENTUNMET NEEDS IN ACUTE PAIN

SESSION IV: POST-OPERATIVE PAIN: PREVENTION AND TREATMENTChairpersons: Corrado Blandizzi (Pisa, Italy) – Elena Catalá (Barcelona, Spain)

05:00 p.m. Chronic Post-Surgical Pain: Epidemiology, Risk Factors and Prevention Antonio Montes (Barcelona, Spain)

05:30 p.m. Acute Pain Mechanisms and Targets for Novel Analgesic Drugs Martin Koltzenburg (London, UK)

06:00 p.m. Guidelines for the Treatment of Acute Pain Stephan Schug (Perth, WA, Australia)

06:30 p.m. Discussion

SATURDAY, September 16th, 2017

SESSION V: ACUTE PAIN: TREATMENTChairpersons: Antonio Montero (Lleida, Spain) – Rosalba Tufano (Naples, Italy)

09:00 a.m. Patient-Controlled Analgesia: What is Left Rudolf Likar (Klagenfurt, Austria)

09:30 a.m. Interventional Approaches to Acute Pain Carlos Tornero (Valencia, Spain)

10:00 a.m. Fast Track Analgesia Francisco Macule (Barcelona, Spain)

10:30 a.m. Discussion

11:00 a.m. Coffee break

PRESIDENTS Antonio Montero, Carmelo Scarpignato, Giustino Varrassi 9

BARCELONA, September 14th-16th, 2017SYMPOSIUM VENUE: UNIVERSITAT DE BARCELONA – PARANIMF

PAIN MANAGEMENTUNMET NEEDS IN ACUTE PAIN

SESSION VI: ACUTE PAIN: TREATMENTChairpersons: Athina Vadalouka (Athens, Greece) – Ricardo Plancarte (San Nicolás, Mexico)

11:30 a.m. Mutimodal Analgesia: Pharmacologic Rationale and Clinical Application Alan D. Kaye (New Orleans, LA, USA)

12:00 a.m. NSAID-Opioid Combinations Carmelo Scarpignato (Parma, Italy)

12:30 p.m. Adjuvant Analgesics in Acute Pain Marco Pappagallo (New York, NY, USA)

01:00 p.m. Discussion

01:30 p.m. Lunch

POST-GRADUATE COURSE – PART II

ACUTE POSTOPERATIVE PAIN (APP) – STRATEGIES FOR MANAGEMENT

CLINICAL CASES

02:30 p.m. APP Relief in Patients with Previous Chronic Pain, or Under Opioid Treatment or Addiction César Margarit (Alicante, Spain)

03:00 p.m. Clinical Cases Discussion Victor Mayoral (Barcelona, Spain)

05:30 p.m. Closing Remarks

PRESIDENTS Antonio Montero, Carmelo Scarpignato, Giustino Varrassi10

BARCELONA, September 14th-16th, 2017SYMPOSIUM VENUE: UNIVERSITAT DE BARCELONA – PARANIMF

PAIN MANAGEMENTUNMET NEEDS IN ACUTE PAIN

GENERAL INFORMATION

SYMPOSIUM VENUEUniversitat de Barcelona – ParanimfGran Via De Les Corts Catalanes, 585Barcelona, Spain

REGISTRATIONThe Symposium is free to attend.Please register on the website:https://webplatform.planning.it/BRC2017/register

SECRETARIAT COUNTERThe Secretariat will be open at the following times: THURSDAY, September 14th, 2017

from 09.00 a.m. to 08.00 p.m. FRIDAY, September 15th, 2017

from 08:00 a.m. to 06.00 p.m. SATURDAY, September 16th, 2017

from 08.00 a.m. to 06.00 p.m.

OFFICIAL LANGUAGEThe offi cial language of the congress will be English. Please note that a simultaneous translation English to Spanish and Spanish to English will be provided.

EUROPEAN CME (ECMEC’S) ACCREDITATIONAn application has been submitted for European CME (ECMEC’s) credits.

LUNCHES AND COFFEE BREAKSLunches and coffee breaks will be served at the congress venue.

CERTIFICATE OF ATTENDANCEThe certificate of attendance will be available on request at the end of the Congress at the Secretariat Counter.

SPEAKERS’ PREVIEW ROOM / SPEAKERS’ LOUNGEInvited speakers must report to the Speakers’ Preview Room at least two hours prior to their presentation to upload and check their presentation. The Speakers’ Preview Room and Speaker’s Lounge will be open during the following times: THURSDAY, September 14th, 2017

from 09.00 a.m. to 08.00 p.m. FRIDAY, September 15th, 2017

from 08.00 a.m. to 06.00 p.m. SATURDAY, September 16th, 2017

from 08.00 a.m. to 06.00 p.m.

TECHNICAL FACILITIESFacilities will be available for computer presentations and overhead projections. A Speakers’ Preview Room with PC (Power-point for Windows) will be available for check and preview of presentations. It is essential that speakers deliver their presentations to the Speakers’ Preview Room at least one hour before the session starts.

PRESIDENTS Antonio Montero, Carmelo Scarpignato, Giustino Varrassi 11

BARCELONA, September 14th-16th, 2017SYMPOSIUM VENUE: UNIVERSITAT DE BARCELONA – PARANIMF

PAIN MANAGEMENTUNMET NEEDS IN ACUTE PAIN

HOW TO REACH THE SYMPOSIUM VENUE

METRO: The nearest metro station is called Universitat (red line L1 and purple line L2). Alternatively, you can stop at Catalunya (red line L1 and green line L3) or Passeig de Gràcia (purple line L2, green line L3 and yellow line L4), which are ten minutes walking from the venue. BUS: There are different bus routes which stop in front of the conference venue (Plaça Universitat or Aribau – Gran Via). All the following routes stop within walking distance to the Universitat de Barcelona: 50, 54, 59, 63, 66, 67, 68, H12 and V13. Please beware that Barcelona buses operate vertically (V), horizontally (H) or diagonally (D), which is indicated in the name of each bus route. AIRPORT: from both Terminal 1 and Terminal 2, you can take the Aerobus which stops just in front of the symposium venue. Alternatively, you can take the train that leaves the Terminal 2 and stops at Barcelona, Passeig de Gràcia (R2), which is 15-minute walking to the venue.

TAXI: you will easily distinguish Barcelona city taxis as they bear a black and yellow livery. There is a taxi rank just in front of the Universitat de Barcelona. You can also hail a taxi by calling Radio Taxi (+34 933 033 033).

NOTES

PRESIDENTS Antonio Montero, Carmelo Scarpignato, Giustino Varrassi

BARCELONA, September 14th-16th, 2017SYMPOSIUM VENUE: UNIVERSITAT DE BARCELONA – PARANIMF

PAIN MANAGEMENTUNMET NEEDS IN ACUTE PAIN

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ORGANIZING SECRETARIATCME PROVIDER

Via Guelfa 9 – 40138 Bologna (Italy)www.planning.it

Project leader: Michela GorgoglioneE-mail: [email protected]

Phone +39 051 300100 Ext. 134Mobile +39 346 0394052Fax +39 051 309477