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1 2016 Drug Trends Series – Opioids & Compounds First Script 2016 Drug Trends Series Part 3: Assessing opioids and compounds Published August 2017

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Page 1: 2016 Drug Trends Series · 5 2016 Drug Trends Series Opioids & Compounds irst Script Top Opioid Trends, Unmanaged 2016 Trend 2015-2016 Medication % of Total % of Total Scripts Cost

1 2016 Drug Trends Series – Opioids & Compounds First Script

2016 Drug Trends SeriesPart 3: Assessing opioids and compounds

Published August 2017

Page 2: 2016 Drug Trends Series · 5 2016 Drug Trends Series Opioids & Compounds irst Script Top Opioid Trends, Unmanaged 2016 Trend 2015-2016 Medication % of Total % of Total Scripts Cost

1 2016 Drug Trends Series – Opioids & Compounds First Script

Aggregate prescription cost per claim, including both managed and unmanaged script usage, decreased 8.4%

Opioid costs and utilization dropped significantly

• A 10.7% drop in utilization drove a 10.7% decrease in cost per claim.• Opioids represented a smaller share of overall cost and utilization, declining 1.2% points and nearly 1% point,

respectively.

Although opioid trends have shown marked improvement for both the managed and unmanaged settings, differences in claim age and severity of injury have driven trends in opioid utilization, costs, and drug mix

• Opioid utilization continued to trend downward for the managed population, both on a per-claim basis (9.3%) and for the percentage of injured workers utilizing opioids (3.1% points). Similarly, the cost per claim has declined substantially (12.5%).

• Non-opioid medications used to treat pain are on the rise with the younger claim age population represented in the unmanaged setting. This helped reduce opioid utilization (down 19.7% per claim), cost (down 19.8% per claim), and the number of injured workers utilizing opioids (down 3.5% points).

Utilization of compound medications continued to fall with the greatest impact occurring in the managed setting

Managed

• The number of injured workers using compounds is 1%, nearly half of what it was in 2015.• Compound costs also dropped by half from 2015, accounting for only 2.5% of all drug spend.• Several key states (NY, CA, TX, PA, and IL) experienced a reduction of more than 50% in both the percent

of claims using compounds and the percentage of cost associated with their usage.

Unmanaged

• The number of injured workers using compounds fell to 3.1%; this is a drop of nearly 25% from 2015.• Costs associated with compounds accounted for 26.1% of all drug spend, down from 31.9% in 2015.• California, the state with the most injured workers using compounds, saw its compound user population

drop 54%, from 7.1% to 3.3%.

Introduction

Highlights

As with the first two editions in Coventry’s 2016 Drug Trends Series, our analysis is based on all calendar-year transactions billed through our Pharmacy Benefit Management (PBM) program, First Script, as well as transactions from medical bill review to reflect the total pharmacy experience for our client base.

This third installment of our series is dedicated to opioids and compound drugs. These two therapeutic classes are frequently discussed in workers’ comp as opioids are prescribed to treat pain associated with injuries and compounds have been growing in popularity with physician dispensers.

We will share aggregate opioid and compound information which includes all drugs; we also will break out the results for comparison into the managed and unmanaged views.

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2 2016 Drug Trends Series – Opioids & Compounds First Script

Cost and Utilization Trend Changes (2015 to 2016)

Aggregate View Data Includes Managed + Unmanaged Prescriptions

Aggregate Key Trends

The Aggregate View Represents:

100% of Total Pharmacy Cost

The charts in this section incorporate all pharmacy transactions that have been shared in the two prior editions of our series. Comparisons between the traditional and aggregate views follow.

Aggregate data indicated a greater decrease in opioid prescriptions and cost per claim, but a smaller decrease in compounds when compared with traditional data. There was a different injury mix for the unmanaged group.

OpioidsTop 10 ClassesAll Classes

Per-claim costs for all prescription drugs decreased 8.4% between 2015 and 2016.

Eight of the top 10 drug therapy classes experienced lower costs in 2016.

100% of Total Prescriptions

Compound usage per claim

Opioid usage per claim

Traditional: -8.5% Aggregate: -10.7%

Dermatological & topical medications

Traditional: +1.3%Aggregate: +5.1%

Traditional: -43% Aggregate: -24.8%

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3 2016 Drug Trends Series – Opioids & Compounds First Script

Aggregate View — High-Impact Drug Classes

Specialty Drugs Specialty Drugs

Compounds Compounds

2016 Aggregate by Volume

2016 Aggregate by Cost*

2015 Aggregate by Volume

2015 Aggregate by Cost

Opioid use continued to decline in 2016.

Compound cost fell 4.2% points, driven by decreases in both utilization per injured worker (24.8%) and cost per script (22.9%).

Opioids Opioids

All Other Classes All Other Classes

Specialty Drugs

Compounds

Opioids

All Other Classes

Specialty Drugs

Compounds

Opioids

All Other Classes

The 1.2% point drop in opioid volume (shown above) has translated into a nearly 1% point drop in opioid cost (as shown in the chart below).

*The numbers reflected in this and other charts throughout this report may not add up to 100% due to rounding.

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4 2016 Drug Trends Series – Opioids & Compounds First Script

Opioid Trends

Top Opioid Trends, Managed

There has been a slow yet continuous shift away from opioid medications to non-opioid therapies. In both the managed and unmanaged populations, opioid prescriptions are increasingly being replaced with non-steroidal anti-inflammatory drugs (NSAIDs), anticonvulsants, and muscle relaxants. To better understand the drivers behind this welcome trend, we have analyzed some of the differences in opioid utilization and cost across claim ages in both the managed and unmanaged populations.

2016 Trend 2015-2016

Medication %ofTotal %ofTotal Scripts Cost Opioid Scripts Opioid Cost per Claim per Claim

Hydrocodone/ 33.1% 9.9% -11.9% -22.1% acetaminophen

Oxycodone/ 15.2% 18.5% -7.5% -8.7% acetaminophen

Tramadol 14.3% 4.0% -4.4% -9.0%

Oxycodone 9.8% 6.9% -3.2% -12.2%

OxyContin® 5.9% 20.7% -10.6% -8.7%

All other opioids 21.7% 40.0% -11.8% -13.7%

Allopioids -9.3% -12.5%

Top 5 Opioid Medications Ranked by Utilization – Managed Prescriptions

The top 5 most utilized opioids,

shown here, accounted for

78.3% of utilization and

60% of cost for all opioids

The number of injured workers

using opioids dropped from

57.3% to 54.2%

Nucynta® Nucynta® ER Only two opioids among the top 20 experienced increasing trends in cost per claim. Both Nucynta and Nucynta ER, schedule II controlled substances well suited for pain conditions requiring a strong opioid component, had price increases above 24%.

8.4%cost per

claim

31.4%cost per

claim

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5 2016 Drug Trends Series – Opioids & Compounds First Script

Top Opioid Trends, Unmanaged

2016 Trend 2015-2016

Medication %ofTotal %ofTotal Scripts Cost Opioid Scripts Opioid Cost per Claim per Claim

Hydrocodone/ 29.9% 10.4% -29.2% -34.9% acetaminophen

Tramadol 26.7% 11.7% -10.8% -7.7%

Oxycodone/ 9.9% 14.9% -19.0% -11.4% acetaminophen

Acetaminophen/ 8.2% 1.7% -9.9% -0.8% codeine

Tramadol/ 6.3% 1.7% -12.1% -42.2% acetaminophen

All other opioids 18.9% 59.7% -20.6% -20.0%

Allopioids -19.7% -19.8%

Top 5 Opioid Medications Ranked by Utilization – Unmanaged Prescriptions

The number of injured workers

using opioids dropped from

24.3% to 20.8%

The top 5 most utilized opioids,

shown here, accounted

for 81.1% of utilization and 40.3% of cost for all opioids

Extended-release tramadol

#6 in utilization #1 in cost per claim

Extended-release tramadol declined substantially for utilization and cost per claim.29% 32.6%

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6 2016 Drug Trends Series – Opioids & Compounds First Script

Opioid Utilization by Claim Age

Opioid Utilization by Claim Age – Managed Prescriptions*

Opioid Utilization by Claim Age – Unmanaged Prescriptions*

20152016

20152016

*Opioid claims only

Greater medical severity among

the managed population drives

opioid usage that results in an

average of 5 opioid scripts per injured

worker using opioids in 2016

Only 32.5% of all unmanaged opioid

scripts are for claims aged 3+ years

Less severe injuries among

the unmanaged population yields an average of 2 opioid

scripts per injured worker using

opioids in 2016

Opioid usage per claim* continues to decline in almost all claim ages for both the managed and unmanaged population.

Injured workers filling opioids in the managed setting contrast significantly in medical severity and drug mix with their unmanaged counterparts.

Managed claims tend to be older with an average claim age of 5.8 years compared with 2.1 years for unmanaged.

70.4% of all managed opioid scripts are for claims aged 3+ years.

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7 2016 Drug Trends Series – Opioids & Compounds First Script

Opioid Cost by Claim Age

Opioid Cost by Claim Age – Managed Prescriptions*

Opioid Cost by Claim Age – Unmanaged Prescriptions*

20152016

20152016

*Opioid claims only

Cost per script for opioids has fallen

3.5%with 7 of the first

10 claim age years experiencing

decreases

Cost decreases in claims aged 1-3 years (73.9% of opioid scripts) have been offset by increases in per script costs for more mature claims.

Overall cost perscript for opioidshas experienced

a negligibledecrease of

0.04%

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8 2016 Drug Trends Series – Opioids & Compounds First Script

Compound Trends — Aggregate View

Injured Workers Filling At Least One Compound Prescription

Compound Cost

2013201420152016

2013201420152016

The percentage of injured workers filling compound prescriptions for

both the managed and unmanaged

populations declined by roughly

1% point

Compound drugs represented only

2.5% of total drug costs

in the managed population as

compared with

26.1% of total drug costs in the unmanaged

populationThe percentage of drug costs associated with compounds declined 2.9% points for the managed population and 5.8% points of the unmanaged population.

Compounds per claim dropped for both populations: 44.2% for managed and 15.4% for unmanaged.

Compounds Represent:

7.7% of Aggregate Cost

1.3% of Aggregate Prescriptions

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9 2016 Drug Trends Series – Opioids & Compounds First Script

Compound Utilization in Top States Ranked by Total Drug Cost

Compound Utilization in Top States – Managed Prescriptions

Compound Utilization in Top States – Unmanaged Prescriptions

20152016

20152016

While not in the top 10 states by total drug cost, 6.1% of scripts in Colorado were for compounds — the highest for all states.

The top 10 states accounted for

47.5% of all injured workers

using compounds

NY, CA, TX, PA, IL, and CT each experienced a more than 50% reduction in the percentage of all claims utilizing compounds.

Five of the top 10 states incurred increasing trends, with CO experiencing the greatest increase at 66.7%.

California accounted for

31.3% of all compound

claimsCalifornia’s 54% reduction in injured workers utilizing compounds was the key driver behind the decrease in unmanaged compound use.

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10 2016 Drug Trends Series – Opioids & Compounds First Script

The top 10 states accounted for

60% of all managed

compound cost

California experienced the

greatest reduction at

43.9%

The percentage of total managed drug costs dropped at least 50% for compounds in NY, CA, TX, PA, and IL.

The top 10 states accounted for 79.6% of all compound cost with CA, PA, and TX representing 59.6%.

Compound Cost in Top States Ranked by Total Drug Cost

Among the top 10 states, Texas had the highest percentage of cost for compounds at 6%.

The percentage of total unmanaged drug costs dropped at least 30% for compounds in CA, GA, and NY.

Compound Cost in Top States – Managed Prescriptions

Compound Cost in Top States – Unmanaged Prescriptions

20152016

20152016

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12 2016 Drug Trends Series – Opioids & Compounds First Script

Conclusion & Recommendations

The opioid and compound drug trends highlighted in this installment of our 2016 Drug Trends Series illustrate the progress made on an aggregate level as well as the differences in these drug categories between the managed and unmanaged populations. As stated in our second installment, understanding the differences between the managed and unmanaged populations allows us to tailor solutions for each of these populations.

• The managed prescription population tends to be made up of injured workers facing greater medical severity and longer-duration claims. The higher rate of opioid utilization in the managed population confirms the importance of directing injured workers to network pharmacies where clinical oversight is most impactful. This allows the PBM to work closely with the prescribers to reduce opioid utilization and identify opportunities for addiction screening and opioid disorder assessments.

• It is encouraging to see trends in both opioid utilization and cost continuing to decline across the aggregate view of claims. This is attributable, in part, to increased attention concerning inappropriate prescribing of opioids and the risks associated with this class of drugs; these include misuse, abuse, and death from overdose. Our early intervention efforts have helped drive down opioid utilization over time as well.

• Extended-release (ER) or long-acting opioid medications are more commonly utilized within the managed injured worker population. These types of opioids are associated with unique risks and present an opportunity to analyze drug mix and ensure that evidence-based recommendations for use are appropriately reflected in the patient’s treatment plan. These recommendations may include the presence of a pain treatment agreement with routine physician evaluation of the continued need for ER opioids, the presence of rescue medication where appropriate, ongoing urine drug monitoring, and ultimately return to work/function for the injured worker.

• Compound utilization and cost declined for both the managed and unmanaged populations in 2016. Payors who leverage processes allowing only compound prescriptions expected to provide medical benefit will continue to see a decline in both utilization and cost.

In our next installment of the Drug Trends Series, we will consider future trends, including specialty drugs and drug formularies.

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13 2016 Drug Trends Series – Opioids & Compounds First Script

Coventry is the leading provider of care and cost management solutions for workers' comp, disability, and auto insurance carriers, third-party administrators, and self-insured employers. We design best-in-class products and services to help our partners return injured workers to work, to play, and to life as quickly and as cost effectively as possible. We accomplish this by developing and maintaining consultative partnerships with our clients and stakeholders, built on a foundation of trust that supports the claims management process.

First Script is the Pharmacy Benefit and Drug Utilization Management Program offered as part of the Coventry suite of products. First Script offers an end-to-end program designed specifically for workers’ compensation. We realize that getting 100% of the prescriptions into the network isn’t the end game; it’s what you do with those scripts that matters. Early triage of each injured worker ensures that injured workers know how and where to get a prescription filled, and permits us to intervene aggressively on potentially problematic opioid utilization at the earliest point possible. Through integration with our bill review and case management programs, we are positioned to capture all prescription activity for utilization and total pharmacy risk management, ensuring that we manage not only the First Script, but Every Script.

Coventry Connect® MobileIndustry leading care and cost management solutions on the go

Coventry Connect technology works with Coventry’s integrated suite of

solutions to help adjusters and case managers make informed decisions

that lead to better outcomes.

3200HighlandAve.•DownersGrove,IL•60515•800.243.2336•www.coventrywcs.com©2017CoventryHealthCareWorkersCompensation,Inc.Allrightsreserved.

The information which is provided herein is offered as a courtesy to our clients. All material is intended for information, communication, and educational purpose only and is in no manner an endorsement, recommendation, or approval of any information. Coventry accepts no liability for the content of this distribution, or for the consequences of any actions taken on the basis of the information provided.

Coventry Workers’ Comp Services@CoventryWC