1.skin histol lina 2011
TRANSCRIPT
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Structure of Skin and Its
Appendages
dr. Ni Made Linawati, M.Si
Histology departmentMedical Faculty of Udayana University
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OUTLINE
1. Skin
! "#ick skin
! "#in skin
layer, cells
$. Skin %ppendages
! Se&aceous gland! Sweat gland
! Hair
! Nail
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Structures of the Skin
'pidermis
(ermis
Hypodermis
Hair follicle
Sweat pore
Nerves
MuscleSweat
gland
Fat
Se&aceous
gland
Hair)loodvessels
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Functionals of the skin structure
1. *ermea&ility &arrier epidermis
$. *rotection from pat#ogen,uv
+. "#ermoregulation sweat gland, &lood vessel
. -eception of continual sensations from t#e
environment merkel cells, meisners
. '/cretion sweat gland
0. *#ysical appearance melanocyte
. 2ound repair3regeneration
4. %&sorpsion epidermis
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kin layer
1. Epidermis
2. Dermis
3.Hypodermis
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EPIDERMIS 5rigin from ectoderm Stratified s6uamous keratini7ed epit#elium or stratums cells types
Dermis 5rigin from mesoderm 8onnective tissue cells, matri/9 fi&ers $ layerscontents
HIPOE!"IS! Loose connective tissue! %ccumulate of adipocyte cells
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CELLS OF THE EPIDERMIS
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I##igrant $ells of The Epider#is
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%eratinoc&tes
"#e largest population ofcells
%rranged in five layer
Morp#ology different
depend on t#e strata
8ells in diff. strata produced
diff. type of keratin protein
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%eratinoc&te differentiation
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"elanoc&tes
Neural crest
epidermis Synt#esi7e melanin (eep layer of epidermis Morp#ology rounded or
cu&oid9 proc of cytoplasmstratum spinosum 8ytoplasmgranules
melanosomescytocrinesecretion
*rotect us from uvradiation ::::::
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E!"IS
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!eticular La&er
Papillar& La&er
dermis: Papiar! and Reticuar a!ers
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SU($UTANEOUS LA)E!
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S%IN APPENA'ES
S')%S'5US =L%N(
S2'%" =L%N(
H%>-
N%>L
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SE(ASEOUS 'LAN
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SE(ASEOUS 'LAN
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S*EAT 'LAN
'88->N' S2'%" =L%N(; M'-58->N'
%*58->N' S2'%" =L%N(UN('- "H'
>NFLU'N8' 5F H5-M5N'S
M5(>F>'( =L%N( 8'-UM>N5US %N(
M%MM%-? =L%N(
S'8-'"5-? UN>", (U8",
M?5'*>"H'L>%L 8'LLS
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S"eat #ands
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S*EAT 'LANS +E$$!INE,
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S*EAT 'LANS +APO$!INE,
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S-eat 'lands
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HAI!
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HAI! Filamentous, keratini7ed
structures t#at pro@ect
from t#e epidermalsurface of t#e skin
"ype+
Hair follicles develop from
epidermis and invade t#edermis and #ypodermis
Hair root and dermalpapilla#air &ul&
Hair s#aft
8ells matri/ cells,melanocytes
HAI! FOLLI$LE
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HAI! FOLLI$LE
Functions warm, s#ield,filter
Hair growt# cyclesanagen, catagen, telogen
NAIL
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NAIL
Aeratini7ed epit#ellialcells arranged in plates of#ard keratin
"erm nail plate, nail &ed,nail matri/, nail root,eponyc#ium,#yponyc#ium, lunula
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SU""A!)
"#ick vs t#in skin different
! in epidermis Bstratum vs C
Skin appendages
! Sweat =land Becrine vs apocrine S=C
! Se&aseous =land
Secretion9 location9 open9 #ormonal influence9
etc
! Hair, nail
skin vs #air vs nail differ in keratin type
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THAN% )OU