1 | P a g e

Australian Centre for NanoMedicine: 2013 Annual Report. 2 | P a g e

ACN

Contents

Directors’ Report 3

ACN Mission Statement 4

ACN Vision and Goals 5

ACN’s Management Board 6

ACN’s Advisory Panels 7

Team ACN 8

Key ACN Activities 9

Total Projects Commenced in Year 10

Number of DEST “A” and Publications 11

Number of Industry/Government Partner Based Projects 14

Number of Media References/Mentions 15

Number of Australian Conferences Presented 17

Number of International Conferences Presented 18

Number of Community/Practice Presentations 19

Post Doc Years 20

Post Graduate Students 20

PhD Completions 20

NanoMed Conference in Australia 21

Stakeholder Seminar Series (Off Campus) 22

Other External Stakeholder Meetings (On Campus) 23

Grant Funding 24

Other Achievements 25

ACN Financial Report 28

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ACN

Director’s Report

In this the 2013

Annual Report of

the Australian

Centre for

NanoMedicine

(ACN) we reflect

over the last

twelve months

with much pride

on our research

achievements and

how the work of our 50+ team is impacting from our

research benches, all the way to clinical bedside.

Team ACN continues to work on diseases including

neuroblastoma, lung, blood and pancreatic cancers,

while diabetes, asthma and uveitis are part of our non-

cancer portfolio. Our skills in drug delivery, imaging

agents and diagnostic devices are producing valuable

outcomes reflected in the over 50 publications released

between our inception in July 2011 to the end of 2013.

Our success in grants through Australian/State

Governments, cancer institutes and industry

collaboration reached $AUD8M ($3.4M in 2013), with

this figure excluding ACNs involvement in two

Australian Research Council’s Centre of Excellence bids

that were announced in December 2013 for

commencement in 2014.

The two Centre’s, The ARC Centre of Excellence in

Convergent Bio-Nano Science and Technology includes

ACN Team members Scientia Prof Justin Gooding, Prof

Maria Kavallaris, A/Prof Palli Thordarson; while the

ARC Centre of Excellence in Advanced Molecular

Imaging, includes Prof Kat Gaus.

ACN’s has also enjoyed success with a number of

prestigious awards bestowed on individuals. While each

award is great recognition to ACN, there is one award

presented to Maria Kavallaris that is extremely special.

Maria was included in the National Health and Medical

Research Council’s list of High Achievers. We at ACN

know Maria is an excellent researcher and human being,

but it was great to have it publically acknowledged.

Also success for Justin Gooding and Kat Gaus both

winners in the NSW Science and Engineering Awards.

Kat in the Excellence in Biological Science division and

Justin in Emerging Research.

At ACN we are passionate about finding ways to

advance nanomedicine. To aid this mission, we worked

with the Australian Nanotechnology Alliance resulting in

a change of that organisation’s direction from “general

nanotechnology” to nanomedicine. Subsequently

ANA’s name changed to the Australian Society for

NanoMedicine (ASNM).

The decision taken by UNSW in 2011 to established our

unique research centre incorporating researchers from

UNSWs faculties of Engineering, Medicine and Science

and our strategic vision to create disease focused teams

incorporating Team ACNs skills in drug delivery,

diagnostics and imaging, has, in less than three years

brought recognition to UNSW and recognition to

Australia that we are world leaders in this

research/medical discipline.

We hope you enjoy reading about all these important

activities and events of the Centre and we look forward

to reporting on more exciting research and successes in

the future.

PROFESSOR MARIA KAVALLARIS ||

SCIENTIA PROFESSOR JUSTIN GOODING

Australian Centre for NanoMedicine: 2013 Annual Report. 4 | P a g e

ACN is about converging

nanotechnology and

medicine for the

prevention, diagnosis

and curing of disease.

ACN

Mission Statement

The Australian Centre for NanoMedicine (ACN) combines medicine, science and engineering to deliver therapeutic solutions to research problems in medicine. The ACN will become the hub of all nanomedicine research in Australia.

Australian Centre for NanoMedicine: 2013 Annual Report. 5 | P a g e

Summary ACN Objective:

Converge nano research from

engineering and science into

medical research to seek

novel therapies

Create a new academic area of

research and education using

a disease focus

Translate research into

solution driven medicine

Create domestic and

international alliances to

identify research

opportunities

Be an Australian first and a

model for future international

NanoMedicine Centres.

ACN

Vision and Goals Through a commitment to research, education, knowledge transfer and commercialisation, ACN will be dedicated to the prevention, diagnosis and curing of diseases. ACN will be the focus of nanomedicine research in Australia and will attract leading edge staff and students to UNSW.

Internal UNSW goals:

Establishing a world-class multidisciplinary nanomedicine centre

Bringing the existing research strength in nanomedicine at UNSW under a distinct banner

Providing a significant impetus in nanomedicine research and encourage the UNSW research community to work in this area and then using this as a springboard for ARC, NHMRC and international funding

Externally communicable goals: Bringing together a multidisciplinary team of internationally recognised polymer chemists, engineers and other technologists with clinical and medical practitioners to more clearly understand the requirements to deliver improvements in health

Showcasing and promoting nanomedicine through forums, publications, conferences and news outlets and seek feedback

Establish links with external UNSW stakeholders to conduct research and create opportunities for participation

Improving the quality of undergraduate and postgraduate education/

supervision, conferences news outlets and seek feedback

Providing funding support to attract researchers with interests in nanomedicine to UNSW generating critical mass

Working with Australian decision makers to deliver on national priorities for scientific excellence and industrial competitiveness

Partnering with other academics and commercial ventures to contribute to advances in the field

Establishing an annual nanomedicine conference in Sydney as a main conference in the Asia-Pacific region, and using this to leverage a strong network involving medical institutes and companies

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ACN

Management Board ACN has a Management Board with a structure based on the UNSW Centres model. The Board consists of the following people: Management Board Member Meeting

12/03/2013 Meeting

06/08/2013 Meeting

12/11/2013

Prof Graham Davies (Chairman), Dean of Engineering, UNSW

Prof Merlin Crossley, Dean of Science, UNSW

Prof Peter Smith, Dean of Medicine, UNSW*

Prof Maria Kavallaris, Head of Program, Tumour Biology and Targeting Program, Children's Cancer Institute Australia

Prof Justin Gooding, School of Chemistry, UNSW

Prof Ian Dawes, School of Biotechnology and Biomolecular Sciences, UNSW

Prof Peter Gunning, School of Medical Sciences, UNSW

Ms Carla Gerbo, Australian Centre for NanoMedicine, UNSW

*Professor Peter Smith nominated Prof Peter Gunning as his representative

ACN does not have an Advisory Committee; however ACN has established three advisory panels that assist ACN in its positioning towards the Australian leader in this burgeoning field.

Australian Centre for NanoMedicine: 2013 Annual Report. 7 | P a g e

ACN

Advisory Panels

Strategic Advisory Panel

ACN’s Strategic Advisory Panel provides advice on strategic activities including future directions and opportunities, assisting with the clarification and attainment of our vision, creating strategies, implementing actions and measuring results. Strategic panel members include:

Prof Chris Fells

Prof Mark Wainwright

Medical Advisory Panel

ACN’s Medical Advisory Panel is made up of leading clinicians that provide independent medical advice on specific research projects being undertaken. Medical Advisory Panel members include:

Prof Glenn Marshall (Paediatric Haematologist and Oncologist, Professor of Paediatrics and Director of the Centre for Children’s Cancer and Blood Disorders, Sydney Children’s Hospital),

Prof Jacob George (Professor of Gastroenterology and Hepatic Medicine and Head of Gastroenterology and Hepatology at Westmead Hospital)

A/Prof Craig Lewis (Director, Medical Oncology at The Prince of Wales Hospital).

Industry Advisory Panel ACN's Industry Advisory Panel will assist ACN to adopt leading research and provide advice on translating research to the benefit of health based organisations

Dr Jason Harcup, Vice President of R&D and Head of Unilever’s Research Organisation (China)

Dr Sridhar Iyengar, Chief Technical Officer and Founder, Agamatrix (USA)

Dr Peter French, Chief Executive Officer, Benitec (Australia)

Australian Centre for NanoMedicine: 2013 Annual Report. 8 | P a g e

ACN

Team ACN ACN Directors: Prof Justin Gooding

Prof Maria Kavallaris

Prof Tom Davis (resigned July 2013)

Deputy Director: A/Prof Cyrille Boyer

Management: Carla Gerbo

Project Leaders: Prof Katharina Gaus

Conjoint Prof Ivan Greguric

Dr Joshua McCarroll

A/Prof Shelli McAlpine

Dr Palli Thordarson

Dr Renee Whan Research Fellows: Dr Elizabeth Hinde

Dr Stuart Lowe

Dr Helder Marcal (left 2013)

Dr Sharon Sagnella

Dr Orazio Vittorio

Dr S R C Vivekchand

Post Docs: Dr Muhammad Alam

Dr Mariana Beija (left mid 2013)

Dr Ales Benda

Dr Hien Duong

Dr Rafael Erlich (left 2013)

Dr Mathew Jones (left 2013)

Dr Bunyamin Karagoz

Dr Astrid Magenau (left 2013)

Dr Jeremie Rossy

Dr Stacy Slavin (left 2013)

Dr Alex Soeriyadi

Dr Thibault Tabarin

Dr David Williamson (left 2013)

Dr Jason Xu

Postgraduate Students and Researchers:

Swahnnya de Almedia

Amir Atme (Masters)

Shree Augustina

Johan Sebastian Basuki

Carola Benzing

Quill Bowden

Xin Chen (left 2013)

Xiaoyu (Jet) Cheng

Kyloon Chuah

Rhea Cornely

Lars Esser

Zoe Fairjones

Christopher Fife

Bakul Gupta (completed PhD)

Cheng (Johnson) Jiang

Felicity Kao

Alexandre Kross

Daniel Li (Left 2013)

Jinna Liu (completed masters)

Xun Lu

Shyam Sundar Malli Prakash

Mahdie Mollazade

Siti Hawa Ngalim (left 2013)

Stephen Parker

Maryam Parvez

Abigail Pollock

John Rondolo (completed masters)

Sema Sevimli (completed PhD)

Ahmed Abu Siniyeh

Roya Tavallaie

Yui Yamamoto

Zhengmin Yang (research assistant)

Yong (Jerry) Lu

Ying Zhu

Australian Centre for NanoMedicine: 2013 Annual Report. 9 | P a g e

ACN

Key Activities The table below provides a summary of ACNs performance for the year in relation to its identified non-financial targets devised at the

time ACN was established. Columns show both forecast and actual outcomes.

Non-Financial Targets Actual 2011

Forecast 2012

Actual 2012

Forecast 2013

Actual 2013

Total Projects commenced in year

4 2 2 2 2

Number of DEST “A” Publications

10 15 18 20 29

Number of industry/Government partner based projects

2 2 4 2 7

Number of media references/mentions

5 10 50 10 18

Number of Australian conferences presented

3 4 12 5 15

Number of international conferences presented

3 4 31 5 25

Number of community/practice presentations

3 3 22 3 15

Post doc years 3 4 14 5 15

Post graduate students (actuals) – PhD and Researchers

2 4 31 6 33

PhD Completions (cumulative)

0 2 2

Associate Faculty Staff 2 3 4

NanoMed Conference in Australia

1 1 1 1 1

Stakeholder seminar series (off campus)

2 2 5 2 6

Other external stakeholder meetings (on campus)

2 2 6 2 3

Clinician/Research Roundtable

1 1 0 1

Generate additional external research grant income of at least $1,200,000 by 2013

$2,155,732

$2,377,924

$3,458,634

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Non-Financial Targets 2011 Forecast 2012

Actual 2012

Forecast 2013

Actual YTD 2013

Total Projects commenced in year Note: Diagram 1: Enabling Research Diagram 2: Application Research

4 2 2 2 2

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Non-Financial Targets 2011 Forecast

2012

Actual

2012

Forecast

2013

Actual

YTD

2013

Number of DEST “A”

Publications

10 15 18 20 29

February 2013: Oncogene Advance

(DOI: 10.1038/ onc.2013.11). RNAi-

mediated stathmin suppression

reduces lung metastasis in an

orthotopic neuroblastoma mouse

model. F L Byrne, L Yang, P A

Phillips, L M Hansford, J I Fletcher, C

J Ormandy, J A McCarroll, M

Kavallaris

February 2013: Analytical and

Bioanalytical Chemistry (DOI:

10.1007/s00216-013-6782-8). The

impact of antibody/epitope affinity

strength on the sensitivity of

electrochemical immunosensors for

detecting small molecules. Sook Mei

Khor, Pall Thordarson, J Justin

Gooding

March 2013: RSC Advances (DOI:

10.1039/c3ra000102d). Sintered gold

nanoparticles as an electrode material

for paper-based electrochemical

sensors. Devi D Liana, Burkhard

Raguse, Lech Wieczorek, Geoff R

Baxter, Kyloon Chuah, J Justin

Gooding, Edith Chow

April 2013: Journal of Visualized

Experiments (DOI:10.3791/50310).

Creating Adhesive and Soluble

Gradients for Imaging Cell Migration

with Fluorescence Microscopy. Siti

Hawa Ngalim, Astrid Magenau, Ying

Zhu, Lotte Tønnesen, Zoe Fairjones, J

Justin Gooding, Till Böcking,

Katharina Gaus

April 2013: Electroanalysis

(DOI:10.1002/elan.201200333). An

Amperometric Immunosensor Based

on a Gold Nanoparticle-Diazonium

Salt Modified Sensing Interface for

the Detection of HbA1c in Human

Blood. Guozhen Liu, Sridhar G

Iyengar, J Justin Gooding

April 2013: Australian Journal of

Chemistry (DOI 10.1071/ CH13043).

Demonstrating the Use of Bisphenol

A-functionalised Gold Nanoparticles

in Immunoassays. Joshua R Peterson,

Yang Lu, Erwann Luais, Nanju Alice

Lee and J Justin Gooding

April 2013: Langmuir (DOI:

10.1021/la400358e). Using

supramolecular binding motifs to

provide precise control over the ratio

and distribution of species in multiple

component films grafted on surfaces:

demonstration using electrochemical

assembly from aryl diazonium salts. Gui AL, Yau HM, Thomas DS,

Chockalingam M, Harper JB, Gooding

JJ

April 2013: Molecular Pharmaceutics

(DOI: 10.1021/ mp400049e). Effective

Delivery of siRNA into Cancer Cells

and Tumors Using Well-Defined

Biodegradable Cationic Star

Polymers. Cyrille Boyer, Joann Teo,

Phoebe Phillips, Rafael B Erlich,

Sharon Sagnella George Sharbeen,

Tanya Dwarte, Hien T T Duong, David

Goldstein, Thomas P Davis, Maria

Kavallaris, Joshua McCarroll

April 3013: Electroanalysis

(DOI:10.1002/elan.201200667). Gly-

Gly-His Immobilized On Monolayer

Modified Back-Side Contact

Miniaturized Sensors for

Complexation of Copper Ions. Urszula

E. Wawrzyniak, Patrycja Ciosek,

Micha Zaborowski, Guozhen Liu, J

Justin Gooding

May 2013: Physical Chemistry

Chemical Physics (DOI:

10.1039/c3cp50355k). The detailed

characterization of electrochemically

switchable molecular assemblies on

silicon electrodes. Simone Ciampi,

Michael James, Moinul H Choudhury,

Nadim A Darwish, J Justin Gooding

May 2013: Analyst (DOI:

10.1039/c3an00081h). Functionalised

porous silicon as a biosensor:

emphasis on monitoring cells in vivo

and in vitro. Bakul Gupta, Ying Zhu,

Bin Guan, Peter J Reece, J Justin

Gooding

June 2013: European Journal of

Pharmaceutical Sciences (Volume 49,

Issue 3, 14 June 2013). Quercetin

nanocomposite as novel anticancer

therapeutic: Improved efficiency and

reduced toxicity. Giuseppe Cirillo,

Orazio Vittorio, Silke Hampel,

Francesca Iemma, Paolo Parchi, Marco

Cecchini, Francesco Puoci, Nevio Picci

July 2013: Journal of Materials

Chemistry B (DOI: 10.1039/

b000000x). Cancer phototherapy in

living cells by multiphoton release of

doxorubicin from gold nanospheres.

Valerio Voliani, Giovanni Signore,

Orazio Vittorio, Paolo Faraci, Stefano

Luin, Julia Peréz-Prieto, Fabio Beltram

July 2013: Applied Materials and

Interfaces (DOI 10.1021/

am40060121). Photolithographic

Strategy for Patterning Preformed,

Chemically Modified, Porous Silicon

Photonic Crystal Using Click

Chemistry. Ying Zhu, Bakul Gupta,

Bin Guan, Simone Ciampi, Peter J

Reece, J Justin Gooding

July 2013: ChemPhysChem (14, 2183-

2189). Protein Resistance of Surfaces

Modified with Oligo(Ethylene Glycol)

Aryl Diazonium Derivatives. Callie

Fairman, Joshua Z Ginges, Stuart B

Lowe, J Justin Gooding

July 2013: ACS medical Chemistry

Letters (DOI: 10.1021/ ml400082b).

Effectively Delivering a Unique Hsp90

Inhibitor Using Star Polymers. Seong

Jong Kim, Deborah M Ramsey, Cyrille

Boyer, Thomas P Davis, Shelli R

McAlpine

August 2013: Macromolecules (DOI:

10.1021/ma401250f). Grafting of

P(OEGA) Onto Magnetic

Australian Centre for NanoMedicine: 2013 Annual Report. 12 | P a g e

Nanoparticles Using Cu(0) Mediated

Polymerization: Comparing Grafting

“from” and “to” Approaches in

the Search for the Optimal Material

Design of Nanoparticle MRI Contrast

Agents. Johan S Basuki, Lars Esser, Per

B Zetterlund, Michael R Whittaker,

Cyrille Boyer, Thomas P Davis

August 2013: Macromolecules (DOI:

10.1021/ma401171d). Polymer-

Grafted, Nonfouling, Magnetic

Nanoparticles Designed to Selectively

Store and Release Molecules via Ionic

Interactions. Johan Sebastian Basuki,

Hien T T Duong, Alexander

Macmillan, Renee Whan, Cyrille

Boyer, Thomas P Davis

September 2013: Journal of Materials

Chemistry B (DOI:

10.0139/C3TB21090A) Size-dependent

Nanographene Oxide as a Platform

for Efficient Carboplatin Release.

Sami Makharza, Giuseppe Cirilloa,

Alicja Bachmatiuk, Orazio Vittorio,

Rafael Gregorio Mendes, Steffen

Oswald, Silke Hampel, Mark H

Rümmelic

September 2013: Biomaterial Science

(DOI 10.1039/C3BM60148J). Stimuli-

responsive functionalized mesoporous

silica nanoparticles for drug release in

response to various biological stimuli.

Xin Chen, Xiaoyu Cheng, Alexander H

Soeriyadi, Sharon M Sagnella, Xun Lu,

Jason A Scott, Stuart B Lowe, Maria

Kavallaris, J Justin Gooding

September 2013: ACS Macro Letters

(DOI: 10.1021/ mz4004375). Selective

Postmodification of Copolymer

Backbones Bearing Different

Activated Esters with Disparate

Reactivities. Yang Li , Hien TT Duong,

Mathew W Jones, Johan S Basuki,

Jinming Hu, Cyrille Boyer, Thomas P

Davis

October 2013: Recent Advances in

Drug Delivery Research (ISBN: 978-1-

62948-228-6). ACN and the Children's

Cancer Institute Australia produced

Chapter 7. Polyphenol Conjugate:

Synthesis and Potential Biomedical

Applications . O Vittorio, G Cirillo, S

Hampel, F Iemma and M Kavallaris,

Children’s Cancer Institute Australia,

Lowy Cancer Research Centre,

University of New South Wales,

Sydney, Australia and others

October 2013: Polymer Chemistry

(DOI: 10.1039/ C3PY01306E).

Polymerization-Induced Self-Assembly

(PISA) - control over the morphology

of nanoparticles for drug delivery

applications. Bunyamin Karagoz, Lars

Esser, Hien T Duong, Johan S Basuki,

Cyrille Boyer, Thomas P Davis

October 2013: ACS NANO (DOI:

10.1021/nn404407g). Using

Fluorescence Lifetime Imaging

Microscopy to Monitor Theranostic

Nanoparticle Uptake and Intracellular

Doxorubicin Release. Johan S Basuki,

Hien TT Duong, Alexander Macmillan,

Rafael B Erlich, Lars Esser, Mia C

Akerfeldt, Renee Megan Whan, Maria

Kavallaris, Cyrille Boyer, Thomas P

Davis

November 2013: Chemical Science

(DOI: 10.1039/ C3SC52838C).

Magnetic Nanoparticles with Diblock

Glycopolymer Shells give Lectin

Concentration-Dependent MRI

Signals and Selective Cell Uptake.

Johan Basuki, Lars Esser, Hien Duong,

Qiang Zhang, Paul Wilson, Michael R

Whittaker, David Haddleton, Cyrille

Boyer and Thomas P Davis

November 2013: Angewandte Chemie

(DOI: 10.1002/ anie.201202118).

Using an Electrical Potential to

Reversibly Switch Surfaces between

Two States for Dynamically

Controlling Cell Adhesion. Cheuk Chi

Albert Ng, Astrid Magenau, Siti Hawa

Ngalim, Simone Ciampi, Muthukumar

Chockalingham, Jason Brian Harper,

Katharina Gaus, John Justin Gooding

November 2013: Macromolecular

Rapid Communication (DOI:

10.1002/ marc.201300730).

Simultaneous Polymerization-Induced

Self-Assembly (PISA) and Guest

Molecule Encapsulation. Bunyamin

Karagoz, Cyrille Boyer, Tom P Davis

December 2013: Langmuir (DOI:

10.1021/la403669v). Light-Induced

Organic Monolayer Modification of

Iodinated Carbon Electrodes. Callie

Fairman, Muthukumar Chockalingam,

Guozhen Liu, Alexander H Soeriyadi, J

Justin Gooding

December 2013: Polymer Chemistry

(DOI: 10.1039/ C3PY01676E). The

Precise Molecular Location of

Gadolinium Atoms has a Significant

Influence on the Efficacy of

Nanoparticulate MRI Positive

Contrast Agents. Yang Li, Sophie

Laurent, Lars Esser, Luce Vander Elst,

Robert N Muller, Andrew B Lowe,

Cyrille Boyer, Thomas P Davis

.

Australian Centre for NanoMedicine: 2013 Annual Report. 13 | P a g e

INVENTIA

Non-Financial Targets 2011 Forecast

2012

Actual

2012

Forecast

2013

Actual

YTD

2013

Number of industry/Government

partner based projects

2 2 3 2 7

ACN researchers Dr Michael Whittaker and Dr Cyrille Boyer are

working with ANSTO LifeSciences on the Design of New Smart

Polymer structures for dual PET imaging and drug delivery

ACN researchers Prof Tom Davis, Dr Cyrille Boyer and Dr Hien Duong

are working with Dr Jianhua Wang of the Westmead Millennium

Institute on project Liver Fibrosis.

ACN researchers Prof Maria Kavallaris and Dr Joshua McCarroll have

received funding support from Benitec Biopharma for project Lung

Cancer.

A collaborative project is also under way on a NHMRC funded project

grant with Prof Tariq Rana, Sansom-Burham Institute (USA)

ACN Researchers Prof Justin Gooding, Prof Maria Kavallaris and Prof

Tom Davis are working with Dr Julio Ribeiro of Inventia Genetic

Technologies to examine The development of tuneable materials to

allow the three-dimensional printing of cells.

A new partnership between ACN and EnGeneIC Pty Ltd has recently

been established. EnGeneIC’s mission is to change the perception of

cancer from life threatening to curable. They aim to revolutionise the

treatment of cancer through the targeted delivery of therapeutic agents

directly to cancer cells.

AgaMatrix is a development stage venture based in Boston offering

proprietary Digital Signal Processing (DSP) technology that

dramatically improves the functionality and performance of biosensor

devices. AgaMatrix's core DSP algorithms solve a number of immediate

problems in the medical devices market by significantly boosting the

performance of biosensors without costly specialized hardware and

additional chemicals. ACNs Prof Justin Gooding works with AgaMatrix

scientific team.

Australian Centre for NanoMedicine: 2013 Annual Report. 14 | P a g e

Non-Financial Targets 2011 Forecast

2012

Actual

2012

Forecast

2013

Actual

YTD 2013

Number of media

references/mentions

5 10 50 10 18

February 21 2013: Breakthrough in

the Fight Against Childhood Cancer:

Channel 7 News

April 24 2013: How Nanotech is

transforming medicine: Australian

Doctors

August 2 2013: Nine Eureka

Moments: UNSW News Room

August 2 2013: NSW premier honours

top melanoma expert: The Courier

Mail

August 2 2013: NSW premier

honours top melanoma expert:

news.ninemsn.com

August 2 2013: NSW premier

honours top melanoma expert: The

Australian

August 2 2013: NSW premier

honours top melanoma expert: The

West Australian

August 2 2013: NSW premier

honours top melanoma expert: Herald

Sun

August 3 2013: Green Tea Extract

has Anti-Cancer Potential: Sydney

Morning Herald

August 3 2013: Green Tea Extract

has Anti-Cancer Potential:

Zeenews.india.com

August 4 2013: Green Tea Extract

has Anti-Cancer Potential: Deccan

Chronicle

August 5 2013: Triple win for cancer

researchers: UNSW News Room

29 October 2013:

New nanoparticle delivers, tracks

cancer drugs: UNSW News Room

30 October 2013:

New nanoparticle delivers, tracks

cancer drugs: The Conversation

31 October 2013:

New nanoparticle delivers, tracks

cancer drugs: UCL Institute of

Biomedical Engineering

November 1 2013: 2013 Category

Award Winners - Best and brightest

recognised at 2013 NSW Science

and Engineering Awards: NSW

Government Chief Scientist and

Engineer

31/12/2013: Doctor: My Relationship

with Cancer: BBC News

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Non-Financial Targets 2011 Forecast

2012

Actual

2012

Forecast

2013

Actual

YTD 2013

Number of Australian

conferences presented

3 4 12 5 15

November 18-21 2013: Prof Justin Gooding: Plenary address

at the 40th International Symposium on High Performance

Liquid Phase Separations and Related Techniques (Hobart

Australia). Title: Designing and Characterising of Bioaffinity

Surfaces for Sensing

October 31 2013: Prof Justin Gooding: AusBiotech 2013:

Bioeconomy in Transition (Brisbane Australia). Title: Future

Manufacturing Trends

September 8-13 2013: Prof Justin Gooding: invited address at

the 10th Australian Peptide Conference (Penang Malaysia)

.Title: Surface-Bound Peptides for Biosensing and Cell Biology

July 9 2013: Mr Yang (Daniel) Li: 34th Australasian Polymer

Symposium (Darwin Australia). Title: Macromolecular Ligands

for Gadolinium MRI Contrast Agents: Effect of Polymer

Architecture.

July 9 2013: Dr Bunyamin Karagoz: 34th Australasian

Polymer Symposium (Darwin Australia). Title: Preparation of

Amphiphilic Block Copolymers with Various Morphologies in

one Pot Polymerization Reaction.

July 8 2013: A/Prof Cyrille Boyer: 34th Australasian Polymer

Symposium (Darwin Australia). Title: Engineering Polymeric

NanoParticles for Advanced Applications.

July 8 2013: Mr Yang (Daniel) Li: 34th Australasian Polymer

Symposium (Darwin Australia). Title: Intracellular Nitric Oxide

Delivery From Stable NO-Polymeric Nanoparticle Carriers.

July 8 2013: Mr Johan Sebastian Basuki: 34th Australasian

Polymer Symposium (Darwin Australia). Title: Magnetic

Nanoparticles as Dual Chemotherapeutic Delivery and MRI

Contrast Agent

July 1-12 2013: Prof Maria Kavallaris: 2013 International

Science School (ISS). Small Wonders - Big Future. The

proceedings of ISS 2013 includes an interview Maria undertook

on her work "Maria Kavallaris is homing in on cancer".

June 3 2013: ACN PhD student Mr Christopher Fife: Best

Student Poster Prize during Medical Research Week in June.

May 15-17 2013: Prof Maria Kavallaris: 2nd Lowy Cancer

Symposium - Discovering Cancer Therapeutics. (Sydney

Australia). Title: In vivo suppression of the TUBB3 gene using

ddRNAi sensitises non-small cell lung cancer to cisplatin

May 15-17 2013: Prof Tom Davis: 2nd Lowy Cancer

Symposium - Discovering Cancer Therapeutics (Sydney

Australia).

May 5 2013: Prof Justin Gooding: Institute of Glycomics,

Griffith University (Gold Coast Australia). Title:

Nanotechnology and biosensors: From detecting small

molecules to monitoring the activity of whole cells

May 2 2013: Prof Justin Gooding: Eskitis Institute, Griffith

University (Brisbane Australia). Title: Nanotechnology and

biosensors: From detecting small molecules to monitoring the

activity of whole cells

February 6, 2013: Prof Tom Davis: 6th Biennial Australian

Colloid and Interface Symposium, (Noosa Queensland).

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Non-Financial Targets 2011 Forecast

2012

Actual

2012

Forecast

2013

Actual

YTD 2013

Number of international

conferences presented

3 4 31 5 25

December 8-10 2013: Prof Justin Gooding: Keynote address

2th International Conference on Frontiers of Polymers and

Advanced Materials, Auckland NZ.

December 8-10 2013: Dr Alex Soeriyadi: 2th International

Conference on Frontiers of Polymers and Advanced Materials,

Auckland NZ.

October 18-20 2013: Prof Justin Gooding: plenary Taishan

Academic Forum on Life-Organic Analysis and Nano-Chemistry

(TAFLOAN), Qufu City China.

September 29 -October 3 2013: Prof Justin Gooding: ComBio

2013. Perth Australia. Title: Cell Chips: Nanostructured

materials that can report on the release of matrix

metalloproteases from just a few cells

September 9-10 2013: Prof Maria Kavallaris: Workshop on

Chemistry and Biology of Microtubules and Microtubule

Interacting Agents (Beijing, China). Title: Drug Target

Interactions – Role of bIII-Tubulin

September 8-13 2013: Prof Justin Gooding: Invited 10th

Australian Peptide Conference (Penang Malaysia).Title:

Surface-Bound Peptides for Biosensing and Cell Biology

September 8 2013: Mr Yang (Daniel) Li: International

Conference on BioNano Innovations 2013 (ICBNI China 2013).

Title: Macromolecular Ligands for Gadolinium MRI Contrast

Agents: Effect of Polymer Architecture

September 8 2013: Dr Hien Duong: International Conference

on BioNano Innovations 2013 (ICBNI China 2013).

September 8 2013: A/Prof Cyrille Boyer: International

Conference on BioNano Innovations 2013 (ICBNI China 2013).

Title: Engineering Polymeric NanoParticles for Advanced

Applications

September 6 2013: Dr Hien Duong: Tsinghua University China.

Title: Nanoparticles for NO delivery: biomedical applications.

September 5 2013 A/Prof Cyrille Boyer: University of Peking

(China). Title: Engineering nanoparticles for drug delivery

September 4-6 2013: Prof Maria Kavallaris: European

Cytoskeletal Forum (Fribourg Switzerland). The focus of the

28th ECF is The Cytoskeleton in Tissue Repair and Diseases.

Title: TBC

September 3 2013: A/Prof Cyrille Boyer presented at the

University of Hefei (China). Title: Engineering Nanoparticles

for specific delivery of doxorubicin

September 2 2013: A/Prof Cyrille Boyer: University of

Hongzhou (China). Title: Engineering nanoparticles for drug

delivery and imaging

August 19-23: Mr Johan Sebastian Basuki: 15th Asian

Chemical Conference (Singapore). Title: Functionalized

Magnetic Nanoparticles as Dual Chemotherapeutic Delivery

and Magnetic Resonance Imaging Contrast Agent.

June 23-26 2013: Prof Maria Kavallaris: The European

CLINAM & ETPN Summit - Clinical Nanomedicine & Targeted

Medicine: From Antibodies to Nanodrugs, Diagnostic Systems

and Targeted Delivery (Basel Switzerland). Title Targeting lung

cancer using RNAi against TUBB3

June 23-26 2013: Prof Justin Gooding: Invited 87th ACS

Colloid and Surfaces Symposium (UC California Riverside,

USA). Title: Making Silicon Water Friendly for Biosensing and

Biolabelling Applications

June 16-21 2013: A/Prof Cyrille Boyer: European Polymer

Congress (Pisa Italy). Title: Star polymers for the delivery of

chemotherapy drugs

April 1-5 2013: Prof Justin Gooding: Plenary XIX Brazilian

Symposium of Electrochemistry and Electroanalytical (XIX

SIBEE) (Sao Paulo, Brazil). Title: Electrodes that resist protein

fouling when used in biological fluids: Applications for

biosensing, cell biology and implantable electrodes

April 3-4 2013: Prof Maria Kavallaris: Pharmacology

Colloquium Series (University of California Santa Barbara,

USA). Title: Targeting microtubules in cancer therapy

March 15 2013: Prof Justin Gooding: Institute for Analytical

and Bioanalytical Chemistry (Ulm University Germany). Title:

Biosensors: The Benefits of Nanotechnology

March 12 2013: Prof Justin Gooding: Plenary address12th

International Society of Electrochemistry Spring Meeting

(Bochum, Germany). Title: Electrodes that resist protein fouling

Australian Centre for NanoMedicine: 2013 Annual Report. 17 | P a g e

when used in biological fluids: Applications for biosensing, cell

biology and implantable electrodes

March 3 2013: Prof Justin Gooding: School of Chemistry,

University of Geneva Switzerland. Title: Biosensors: The

Benefits of Nanotechnology

February 11-15 2013: Prof Tom Davis: 6th International

Conference on Advanced Materials and Nanotechnology (AMN-

6) (Auckland New Zealand). Title: Nanogel/star polymers as

platforms for therapeutic delivery and bio-imaging

Australian Centre for NanoMedicine: 2013 Annual Report. 18 | P a g e

Non-Financial Targets 2011 Forecast

2012

Actual

2012

Forecast

2013

Actual

YTD 2013

Number of community/practice

presentations

3 3 22 3 15

September 16 2013: Dr Alex Soeriyadi presented at the Team

ACN meeting. Title: Enzymatic responsive materials for

nanomedicine application

August 1 2013: presentation ACN Visiting Professor Prof

Samuel Stupp. Mr Johan S Basuki. Title: Functionalized

Magnetic Nanoparticles for Chemotherapeutic Delivery and

Magnetic Resonance Imaging Applications

August 1 2013: presentation ACN Visiting Professor Prof

Samuel Stupp. Dr Hien Duong. Title: Nanoparticles for NO

delivery: biomedical applications

August 1 2013: presentation ACN Visiting Professor Prof

Samuel Stupp. A/Prof Cyrille Boyer.

August 1 2013: presentation ACN Visiting Professor Prof

Samuel Stupp. Dr Elizabeth Hinde. Title: Measuring

Intracellular Diffusion: a potential tool for monitoring drug

delivery

August 1 2013: presentation ACN Visiting Professor Prof

Samuel Stupp. Dr Orazio Vitorio. Title: Dextran-Catechin

Conjugate: A Potential Treatment against Neuroblastoma

August 1 2013: presentation ACN Visiting Professor Prof

Samuel Stupp. A/Prof Pall Thordarson.

August 1 2013: presentation ACN Visiting Professor Prof

Samuel Stupp. Dr Stuart Lowe. Title: Quantum Dot-Peptide

Conjugates as FRET Probes for the Multiplexed Evaluation of

Enzyme Activity

August 1 2013: presentation ACN Visiting Professor Prof

Samuel Stupp. Ms Bakul Gupta. Title: Porous silicon photonic

crystals for detection of protease activity in vivo

August 1 2013: presentation ACN Visiting Professor Prof

Samuel Stupp. Mr Stephen Parker.

August 1 2013: presentation ACN Visiting Professor Prof

Samuel Stupp. Ms Ying Zhu.

June 17 2013: Ms Joann Teo presented at the June Team ACN

meeting. Title: The delivery of siRNA using Nanoparticles in

Pancreatic Cancer

May 20 2013: Mr Lars Esser presented at the May Team ACN

meeting. Title: New polymeric contrast agents for MRI

April 15 2013: Dr S R C Vivekchand presented at the April

Team ACN meeting. Title: Plasmonics - Applications and New

Directions

March 19 2013: Dr Orazio Vittorio presented at the March

Team ACN meeting. Title: Catechin-Dextran conjugate: a

potential treatment against the pancratic ducted

adenocarcinoma

Australian Centre for NanoMedicine: 2013 Annual Report. 19 | P a g e

Non-Financial Targets 2011 Forecast

2012

Actual

2012

Forecast

2013

Actual

YTD 2013

Post doc years 3 4 14 5 15

Post Docs:

Dr Muhammad Alam

Dr Mariana Beija (left mid 2013)

Dr Ales Benda

Dr Hien Duong

Dr Rafael Erlich (left 2013)

Dr Mathew Jones (left 2013)

Dr Bunyamin Karagoz

Dr Astrid Magenau (left 2013)

Dr Jeremie Rossy

Dr Stacy Slavin (left 2013)

Dr Alex Soeriyadi

Dr Thibault Tabarin

Dr David Williamson (left 2013)

Dr Jason Xu

Dr Dylan Owen

Dr Jeremie Rossy

Dr Stacy Slavin

Dr Alex Soeriyadi

Dr Thibault Tabarin

Dr David Williamson

Dr Jason Xu

Non-Financial Targets 2011 Forecast

2012

Actual

2012

Forecast

2013

Actual

YTD 2013

Post graduate students (actuals)

– PhD and Researchers

2 4 31 6 33

Postgraduate Students and Researchers:

Swahnnya de Almedia

Amir Atme (Masters)

Shree Augustina

Johan Sebastian Basuki

Carola Benzing

Quill Bowden

Xin Chen (left 2013)

Xiaoyu (Jet) Cheng

Kyloon Chuah

Rhea Cornely

Lars Esser

Zoe Fairjones

Christopher Fife

Bakul Gupta (completed PhD)

Cheng (Johnson) Jiang

Felicity Kao

Alexandre Kross

Daniel Li (Left 2013)

Jinna Liu (completed masters)

Xun Lu

Shyam Sundar Malli Prakash

Mahdie Mollazade

Siti Hawa Ngalim (left 2013)

Stephen Parker

Maryam Parvez

Abigail Pollock

John Rondolo (completed masters)

Sema Sevimli (completed PhD)

Ahmed Abu Siniyeh

Roya Tavallaie

Yui Yamamoto

Zhengmin Yang (research assistant)

Yong (Jerry) Lu

Ying Zhu

Bakul Gupta

Cheng (Johnson) Jiang

Felicity Kao

Alexandre Kross

Daniel Li

Jinna Liu

Xun Lu

Siti Hawa Ngalim

Stephen Parker

Maryam Parvez

Abigail Pollock

Ahmed Abu Siniyeh

Roya Tavallaie

Yui Yamamoto

Zhengmin Yang

Yong (Jerry) Lu

Ying Zhu

Non-Financial Targets 2011 Forecast

2012

Actual

2012

Forecast

2013

Actual

YTD 2013

PhD completions - Cumulative 0 2 2

Sema Sevimli

Xin Chen

Australian Centre for NanoMedicine: 2013 Annual Report. 20 | P a g e

Non-Financial Targets 2011 Forecast

2012

Actual

2012

Forecast

2013

Actual

YTD 2013

NanoMed Conference in

Australia

1 1 1 1 1

ACNs unique structure continues with a program of stakeholder engagement that includes the most significant

annual International NanoMedicine conference in the southern hemisphere. Over three days in

Sydney’s CBD, this conference attracts world

leaders in the key areas of targeted delivery,

sensing, diagnostics, regenerative medicine,

imaging and translation of research to practice. In

2013 the conference attracted over 200 attendees

from 23 countries, providing an opportunity to

hear and network with, the very best nanomedicine

researchers including medical clinicians and

industry representatives.

Through this event internationally recognised

names have presented. Plenary speakers have included: Prof Samuel Stupp (Northwestern

University USA); Prof Patrick Stayton (University of Washington USA); Prof Tariq M Rana

(Sanford-Burnham USA); Prof Frank Caruso (The University of Melbourne); Prof Gordon

Wallace, (University of Wollongong); Prof Ian Frazer (Translational Research Institute); Prof

Calum Drummond, (CSIROs Manufacturing, Materials and Minerals); and Prof Mark Kendall,

(Australian Institute for Bioengineering and Nanotechnology), Dr John Mattick (Garvan

Institute of Medical Research), Prof Heather Maynard (UCLA), Dr Scott McNeil –

Nanotechnology Characterization Laboratory (USA), Prof Xiaohu Gao – University of

Washington (USA) and Prof Maria Vicent – Principe Felipe Research Centre (Spain).

Australian Centre for NanoMedicine: 2013 Annual Report. 21 | P a g e

Non-Financial Targets 2011 Forecast

2012

Actual

2012

Forecast

2013

Actual

YTD 2013

Stakeholder seminar series (off

campus)

2 2 5 2 6

July 31 2013: ACN in conjunction with the Lowy Cancer

Research Centre hosted Prof Samuel Stupp, Director, Louis

A Simpson & Kimberly K Querry Centre for Regenerative

NanoMedicine. Director, Institute for BioNanotechnology in

Medicine, Northwestern University USA (Sydney Australia).

Title: Novel Therapies with Biomimetic Supramolecular

Nanostructures

July 29 2013: ACN in conjunction with the Australian

Nanotechnology Alliance and Queensland University of

Technology hosted Prof Samuel Stupp, Director, Louis A

Simpson & Kimberly K Querry Centre for Regenerative

NanoMedicine. Director, Institute for BioNanotechnology in

Medicine, Northwestern University USA (Brisbane

Australia). Title: Biomimetic Strategies in Nanomedicine.

July 23 2013: Prof Maria Kavallaris presented at RMIT

Bundoora Bioscience seminar series. Title: Nanomedicine

strategies for cancer

July 19 2013 : ACN in conjunction with the Monash University

hosted Prof Samuel Stupp, Director, Louis A Simpson &

Kimberly K Querry Centre for Regenerative NanoMedicine.

Director, Institute for BioNanotechnology in Medicine,

Northwestern University USA (Brisbane Australia). Title: Self-

Assembling Peptide Nanostructures for Regenerative Medicine

and Drug Delivery.

June 27-28 2013: Prof Maria Kavallaris presented at CEA

(Commissariat à l'Energie Atomique et aux Energies

Alternatives) Grenoble France

January 20 2013: Dr Cyrille Boyer visited Donghua University

(China), where he presented on Engineering Polymeric

Nanoparticles for Drug Delivery/Imaging and Energy

Sustainability.

Australian Centre for NanoMedicine: 2013 Annual Report. 22 | P a g e

Non-Financial Targets 2011 Forecast

2012

Actual

2012

Forecast

2013

Actual

YTD 2013

Other external stakeholder

meetings (on campus)

2 2 6 2 3

ACN UNSW Seminar Series with speakers including

• Prof Robert Prud’homme, Princeton University USA. Title: Facile Production of Multifunctional

Nanoparticles for Hydrophobic therapeutics by Block-Copolymer-Directed Rapid Precipitation

• Prof Samuel Stupp, Northwestern University USA. Title: Biomimetic Strategies in Nanomedicine

• Professor Eva Harth, Vanderbilt University USA. Title: Nanoparticle delivery systems and

reconfigurable hydrogels.

Australian Centre for NanoMedicine: 2013 Annual Report. 23 | P a g e

Non-Financial Targets 2011 Forecast

2012

Actual

2012

Forecast

2013

Actual

YTD 2013

Generate additional external

research grant income of at least

$1,200,000 by 2013

$2,155,732 $2,377,924 $3,458,634

NHMRC: Prof Katharina Gaus ($601,420). Spatial organization

of T cell signalling: NHMRC Established Career Fellowship

#1059278:

NHMRC: Prof Maria Kavallaris ($601,420). Regulation &

targeting of the cancer cytoskeleton: NHMRC Established

Career Fellowship #1058299:

ARC Discovery: Prof Maria Kavallaris and Prof Linda

Wordeman ($343,000). This study aims to obtain a fundamental

understanding of how the structural domains of the cytoskeletal

protein beta-tubulin are involved in microtubule structures

during cell division and vesicular transport: DP140103290, M

Kavallaris, L Wordeman:

ARC Linkage Infrastructure, Equipment and Facilities (LIEF)

Grant. Gunning, Prof Peter, Prof Maria; etc ($370,000).

Imaging cell and tissue architecture using confocal and super-

resolution microscopy: LE140100166, Gunning, Prof Peter W;

Yang, Prof Hongyuan R; Ittner, A/Prof Lars M; Hardeman, Prof

Edna C; Kavallaris, Prof Maria; King, Prof Nicholas J; Grau,

Prof Georges E; Gamble, Prof Jennifer R; Weninger, Prof Dr

Wolfgang:

The Kids’ Cancer Project Award: Dr Orazio

Vittorio ($25,000) for a research project focusing on

neuroblastoma, the most common childhood cancer

in young children: NO Finance project number as

administered through CCIA not UNSW

Cancer Institute NSW: Prof Maria Kavallaris

successful attained an Infrastructure Grant

($400,000) for major equipment purchase of a pre-

clinical 3D tomographic imaging System:

(13/REG/1-17) M Kavallaris, J Fletcher, P Hogg, A

Katsifis, L Khachigian, R Lock, J McCarroll, G

O’Neill, P Phillips & C Power: Finance project

number: RG133602

UNSW Major Research Equipment and

Infrastructure Scheme: Prof Maria Kavallaris

($42,794). C-Pace Electrical Cellular Stimulation

and Recording System: P Polly, R Whan, J Stehn, P

Gunning, E Hardeman, A Kee, T Fath, S Head, N Di

Girolamo, P Phillips, K Bryant, D Simar, C Geczy, N

Tedla, K Hsu, C Herbert, S Sagnella, M Kavallaris:

Finance project number: RG124522

UNSW GoldStar Award: Prof Maria Kavallaris was

awarded $40,000 for Targeting stathmin in

metastatic cancer: Finance project number:

RG124415

ARC Discovery: Prof Justin Gooding and Dr Peter Reece

($540,000). Smart Surfaces for monitoring cellular activity in

real time: from multiple to single cells: DP110102183 JJ

Gooding, PJ Reece: Finance project number: RM08668

ARC: Professors Justin Gooding, Tom Davis and Maria

Kavallaris in conjunction with Dr Julio Ribeiro of Inventia Pty

Ltd successfully attained an ARC Linkage Grant ($495,000) to

examine The development of tuneable materials to allow the

three-dimensional printing of cells. Industry contribution on this

project was $300,000: LP130101035, JJ Gooding, TP Davis, J

Ribeiro, M Kavallaris: Finance project number: RG124351

Australian Centre for NanoMedicine: 2013 Annual Report. 24 | P a g e

ACN

Other Achievements

ACN members were successful in two Australian

Research Council (ARC) Centre of Excellence

bids. While these Centre’s will not be hosted at

UNSW, ACN members will play major roles.

ARC Centre of Excellence in Convergent Bio-

Nano Science and Technology – ACN Team

members: Prof Justin Gooding, Prof Maria

Kavallaris, A/Prof Palli Thordarson.

($26,000,000) ARC Centre of Excellence in Advanced

Molecular Imaging – ACN Team Member: Prof

Kat Gaus. ($27,999,996)

ACN submitted a National Health and Medical

Research Council (NHMRC) Program Grant.

Unfortunately we weren’t

successful in this round;

however, ACN is

tremendously proud that in

our short existence, we have

submitted two substantial

grants (NHNRC and ARC).

ACNs Professor Maria

Kavallaris announced as a

High Achiever in

Australian Health and

Medical Research.

Australia has an outstanding

record in health and medical research. Our

researchers’ discoveries and ongoing research have

made a significant difference to the lives of people

worldwide.

At a gala Sydney event to celebrate the NSW

Science & Engineering Awards 2013, ACN had

plenty of reason to celebrate with wins in two

categories: Professor Katharina Gaus (Excellence in

Biological Science) and Professor Justin Gooding

(Emerging Research).

Congratulations to ACNs

Prof Maria Kavallaris and

Prof Katharina Gaus,

successful recipients of

NHMRC Established

Career Fellowships.

Dr Orazio Vittorio was interviewed by the

BBC on his personal journey with cancer.

This journey saw Orazio

leave his home country

of Italy in February 2013

to join the Children's

Cancer Institute Australia /

Australian Centre for

NanoMedicine to work on a

solution for childhood cancer.

Prof Maria Kavallaris was successful in a major

equipment grant for the purchase of a pre-clinical3D

tomographic Imaging System. The funding came

from the Cancer Institute NSW Infrastructure

Grant.

Australian Museum

Eureka

Prize

finalists:

Scientia

Professor

Justin

Gooding, Professor

Katharina Gaus and Dr Peter

Reece, University of New

South Wales Professor Justin Gooding’s team of

chemists, physicists and cell biologists has

developed an optical device that can monitor the

activity of captured cells.

ACN/CCIAs Dr Orazio Vittorio

won The Kids' Cancer Project

Award for childhood cancer at the

Premier's Awards for Outstanding

Cancer Research. Orazio’s

research focuses on neuroblastoma, the most

common childhood cancer in young children.

Australian Centre for NanoMedicine: 2013 Annual Report. 25 | P a g e

Professor Maria

Kavallaris and Dr

Joshua McCarroll

were as finalist in

the UNSW Innovation Awards. These Awards

recognise and reward the significant effort and

ingenuity of UNSW staff and students, along with

potential partner organisations, in the creation and

transfer of new knowledge and innovations into

society and the

economy. Maria

and Joshua have

been shortlisted

for their work in

the Development

of a first-in-class

lung cancer

therapeutic.

Maria Kavallaris and Joshua McCarroll won the

People’s Choice Award at the UNSW Innovation

Awards.

ACNs PhD student Christopher Fife won the NSW

Australian Society for Medical Research Best

Student Poster Prize during Medical Research Week

in June.

ARC Linkage Grant. ACNs Directors, Justin

Gooding, Tom Davis and Maria Kavallaris in

conjunction with Dr Julio Ribeiro of partner

company Inventia Pty Ltd, as a result of this grant

will examine The development of tuneable materials

to allow the three-dimensional printing of cells.

ACNs Cyrille Boyer who was appointed by UNSW

to Associate Professor. In July 2013 he was

appointed Deputy Director of ACN.

Australian Doctors magazine reproduced an article

based on the Australian Centre for NanoMedicine.

From cancer drugs to diagnostics, nanotechnology

promises to the ‘next little thing’. Australian Doctor

visits one Australian centre where such advances are

well underway.

ACN had three international post-docs join us in

2013 following success via the UNSW Vice-

Chancellor’s Postdoctoral Research Fellowships.

This fellowship is

awarded to early career researchers of exceptional

calibre wishing to conduct full-time research at

UNSW in any of its areas of research strengths. The

three international researchers are:

Dr Orazio Vittorio, Department of Oncology,

University of Piza (Italy). Orazio will be

working with Prof Maria Kavallaris.

Dr S R C Vivekchand, Department of

Chemistry, Northwestern University (USA). Dr

Vivekchand will be working with Prof Justin

Gooding on nanosensors

Dr Liz Hinde,

Laboratory for Fluorescence

Dynamics, University of

California Irvine. Liz will be

working with Prof Kat Gaus

on how cell integrate external

cues to direct migration using

novel microscopy tools and

nano-structured surfaces

Prof Maria Kavallaris was elected to the Board of

the International Society for Nanomedicine

(ISNM). At the Society's meeting in Basel

Switzerland, Maria became the Australian

representative on ISNMs board, which has the aims

of developing nanomedicine internationally and

boosting international interactions.

ACNs Application to the European Technology

Platform – Nanomedicine (ETPN) was successful

making ACN the only Australian member

organisation. Our representative is Prof Maria

Kavallaris.

ACNs

Prof Justin Gooding was

elected to the board of the

Society of Brain Mapping and Therapeutics -

Australasia (SBMTA)

Australian Centre for NanoMedicine: 2013 Annual Report. 26 | P a g e

ACNs Prof Justin Gooding was elected Local Chair

of the World Biosensor Congress to be Held in

Melbourne in May 2014

ACNs Dr Cyrille Boyer was one of ten Australian's

invited to be part of the 1st China-Australia

Polymer Mission. The Mission is co-hosted by the

Polymer Division, Chinese Chemical Society and the

Royal Australasian Chemical

Institute (RACI) - Polymer

Division with the aim of

bringing together research

collaboration between the two

countries. With a busy

program commencing at

Donghua University (January 20),

which included a

presentation by Cyrille on Engineering Polymeric

NanoParticles for Drug Delivery/Imaging and

Energy Sustainability. On January 22 the delegation

Visited Fudan University and Jiaotong University;

Beijing (23); Tianjin University and Nankai

University (24); Peking University and Tsinghua

University (25).

The International Society of Electrochemistry

appointed ACN's Director, Professor Justin Gooding

as one of its Vice-Presidents.

Two of the four UNSW Engineering Staff

Excellence Awards announced by the Dean of

Engineering Prof Graham Davies went to Team

ACN members: Professional Awards: Carla Gerbo

(Chem Eng) for her work on the implementation and

management of the Australian Centre for

NanoMedicine; Research Award: Cyrille Boyer

(Chem Eng) won for his world leading research in

polymeric nanomaterials which have been exploited

in two different applications – drug delivery and

energy storage

27 | P a g e

ACN

Attachment 1: Financials