1-introduction to biotechnology[1]

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    Introduction to

    Biotechnology

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    Grading System

    50 % - Exam Prelim 30%

    40%- Quies !idterm 30%

    "0%- #lass $ctiities Endterm40%

    -------- ------

    "00% &otal &otal "00%

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    'e(erence Boo)

    Introduction toBiotechnology *+0"+, y 'ay./ erren

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    Biotechnology

    &he mani1ulation o( liingorganisms or 1arts o( organisms toma)e 1roducts use(ul to humans/

    2sing the)noledge o(cells to modi(ytheir actiities

    in order toma)e liingorganismsmore eectie

    in seringeo le/

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    Biotechnology

    It deals ith the mani1ulation o(the genes o( organisms to altertheir ehaior characteristics oralue/

    2sing the hole1lant or animal

    and all thesystems thatma)e u1 theorganism/

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    Biotechnology

    'easons the deelo1ment o(iotechnology has een so di6cult are7

    *", Scientists useliing organismsthat gro and

    re1roduce/

    *+, In caseo( higher-

    orderedanimalsthe care

    and el(areo( theanimalshae to e

    ta)en into

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    'easons the deelo1ment o(iotechnology has een so di6cult are7

    *3, !ani1ulation

    o( cells and cell(unction has to edone care(ullyith many

    sa(eguards togoern the1rocess/

    *4, &he 1ulic isery hesitant toacce1t organismsthat ere 1roduced

    through means theyconsider to eunnatural/ Peo1le

    are reluctant toacce1t anything theydo not understand1articularly i( it

    relates to the (ood

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    Bioin(ormatics

    &he use o( in(ormation technology tostore analye sort lael and sharethe many 89$ se:uences generated

    y genome se:uencing 1ro;ects/ In addition to 89$ se:uences there

    are large collection o( 1roteinse:uences 1rotein structures

    metaolic 1athay descri1tionsresearch articles 1atents and manyother ty1es o( iology-related datamanaged y ioin(ormatics scientists/

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    Bioin(ormatics

    &he )noledge o( genomesand the tools o( iotechnologyhae o1ened u1 ne

    1ossiilities in geneticengineering / Some scientistsare no or)ing in the

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    &he 9eed (or Biotechnology

    8uring the 1ast 50 yearstremendous adances haeeen made in the e6ciency

    ith hich e gro (ood/ !ucho( the increase in (ood1roductiity egan in the"=>0s ith hat as termed

    the Green Revolution/

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    &he 9eed (or Biotechnology

    Green 'eolution as initiateddue to 1oorer :uality land iseing 1ut into 1roduction/

    Green 'eolution hastremendous im1lications not

    only (or (eeding the 1eo1leut also (or the im1act on theenironment/

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    Green 'eolution

    - re(ers to a large increase incro1 1roduction y using

    modern agriculturaltechni:ues/

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    Im1acts o( Green 'eolution

    Fertilizersmade1ossile (orhigh yield

    arieties togro

    success(ully/

    rr ga on

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    rr ga onBe(ore the Green reolution

    agriculture as seerely limitedto areas ith a signi

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    &he 9eed (or Biotechnology

    &he 1resent rate o( (ood1roduction cou1led ith thegroing orld 1o1ulation meansthat many countries stand a realdanger o( running out o( (ood inthe (uture/

    Biotechnology holds an enormous

    1otential (or (eeding the orld?s1o1ulation in an enironmentallysustainale ay/

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    #olumn $#olumn B

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    &he 9eed (or Biotechnology

    It is 1ossile to engineer 1lants andanimals ith :uality traits such as

    increased nutritional content or theaility to 1roduce medically use(ul1roteins through iotechnology/

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    Researchers Hope Super BananasWill Combat Vitamin A Defciency

    Source: Time Magazine , June 16, 2014

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    Researchers

    Hope SuperBananasWill Combat

    Vitamin ADefciency

    Biotech ananas (orti

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    A&he conse:uences o(itamin $ de00000 childrenorldide dying eachyear and at least

    another 300000 going

    lindC the 1ro;ectleader Pro(essorDames 8ale (rom$ustralia?s Queensland

    2niersity o(&echnology told $P*$gence des euillesPoliti:ues,/

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    Researchers Hope Super

    Bananas Will CombatVitamin A Defciency

    &he trials ill last (or ee)s ith thesu11ort o( Bill and !elinda Gatesoundation/ 'esults ill e aailale atthe end o( +0"4 and commercialiation

    is ex1ected to start y +0+0 in 2ganda/

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    Researchers Hope Super

    Bananas Will CombatVitamin A Defciency

    &he technology is also intendedto e trans(erred to other $(ricancountries including 'anda#ongo Fenya and &anania/

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    Plant Biotechnology

    Plants hae een geneticallymodi

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    Plant Biotechnology

    ther iotech cro1s hae eenmodi

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    Plant Biotechnology H

    Phytoremediation

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    It is orth noting here that 1hytoextraction and1hyto

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    $nimal Science

    Early ciiliations learned to ma)echeese and other (ood 1roducts (rommil) y using animal enymes and

    acteria/ Scientists are no on the erge o(

    ma)ing animal clonina 1racticalmeans o( re1roducing animals ith

    su1erior genetics/ $nimal cloning is the 1rocess o(

    ma)ing an exact genetic co1y o( ananimal/

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    $nimal

    Sciencearmed salmon that reach

    mature sie in a (raction o(the usual time/ &he grothis s1eeded u1 y theinsertion o( to genes onelin)ed to the 1roduction o(groth hormone and asecond to ensure grothcontinues een in ery coldtem1eratures/

    &he technology allos

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    $nimal Science

    Goats and cos that 1roduce thera1eutic

    1roteins in their mil)/ &hera1eutic 1roteinsare used to treat human diseases/ &heyinclude hormones antiodies accinesgroth (actors and lood clotting (actors/

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    $nimal Science

    !edical mice ithhumanli)e immunesystems/

    &he 2/S/ team o(

    scientists trans1lantedhuman one marrocells and other humantissue into miceithout a (unctioning

    immune system/ &hisgae the mice as1ectso( the human immunesystem/htt17JJconsumer/healthday/comJhealth-technology-in(ormation-

    "KJresearch-and-deelo1ment-health-nes-5>KJmouse-ith-

    human-li)e-immune-system-could-adance-aids-research-

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    Pigs that 1roduce 1hytaseenyme in their salia

    leading to lo-

    1hos1horus manure thatis more enironmentally(riendly/

    Im1acts o( high-1hos1horus leel7 $lgae gro (aster than ecosystems can handle/ Large groths o( algae are called algal looms

    and they can seerely reduce or eliminateoxygen in the ater leading to illnesses in

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    !edicine

    &hera1eutic 1roteins accines and othermedicines may e 1roduced in geneticallyengineered cell cultures throughbiomanu!acturin such as humaninsulin 1roduced in acteria/

    &he cells o( hole iotech 1lants andanimals also may e geneticallyengineered to 1roduce 1harmaceuticals*1harming,/

    Personalied medicine loo)s at thegenome o( indiidual 1atients todetermine molecular causes o( diseaseand identi(y treatments that may e most

    eectie/

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    !edicine

    Personalied genomics is a ne

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    &he Enironment

    Biotechnology is used inmonitoring and cleaning u1 theenironment/

    Plants hae een deelo1ed thatcan indicate hether or not anarea is contaminated ith1ollutants/ &his allos (or early

    detection o( contaminants andremedial measures can e ta)ene(ore the 1rolem ecomesserious/