06 persisten desai · 2013-08-02 · app supports real-time reporting of drug delivery cycles,...

© 2013 Persistent Systems Ltd

www.persistentsys.com

Persistent Systems SanGeniX Solution on HANA Aarti Desai, Ph.D. Senior Domain Specialist

2 © 2013 Persistent Systems Ltd

Persistent at a Glance Ex

perie

nce

Gro

wth

The

Prac

tice   Publically listed (BSE,

NSE)

  $237.8M FY13 revenue

  Rs 1,294.51 crore FY13 revenue

  23% CAGR

  U.S., APAC and EMEA regions

  6750+ Employees

  ISO 9001:2008

  ISO 27001:2005

  ISO 14001:2004

  OSHAS 18001:2007

•  350 Customers

•  3000+ Product releases in last 5 years

•  14 of Top 20 technology companies in the world are our customers

•  23 Years in business

Leading vendor in Global OPD & Specialty Application Development & Management (ADM)

– Global Services Media

Top 3 player in Smartphone Application Development

– Forrester Research, 2011

Leading Player in Software/ ISV R&D & Consumer Software Segments. Ranked Highly in Cloud & Enterprise Mobility Segments

– Zinnov Management Consulting

Named a “Leader” in the IAOP 2013 Global Outsourcing 100 service providers list

– IAOP

“2013 Computerworld Honors Laureate”

– ComputerWorld


Victoria Seattle

Chicago Toronto

Quebec

Boston

Ohio

Dallas

San Jose

Scotland Netherlands

France

Hyderabad Goa

Pune Nagpur

Singapore

Tokyo

Sales Office Delivery Center

…and more than 6600 employees.

Malaysia London

…With a Global Footprint

Bangalore


www.persistentsys.com

Recognized R&D Center by Department of Scientific and Industrial Research (DSIR), Govt. of India


Four Focus Areas

Partners in Innovation

Systems Biology Next Generation Sequencing (NGS) Data

Analysis

Diabetes Research

Lab Informatics


NGS Data Analysis Group Key Activities •  Developing a comprehensive, affordable and user

friendly data analysis suite. •  Performing analysis of NGS data in a collaborative

manner with leading research institutes in India to validate and fine tune the data analysis pipelines.

•  Establishing thought leadership by publishing in peer-review journals, magazines and public forums.

Key Collaborators

Performed de novo genome assembly and genetic variation analysis of Rubella virus for

submission to a regulatory body.

DBT funded NGS analysis suite development project A 3 year project funded by DBT to develop SanGeniX, an end-to-end NGS data analysis suite.


  Web-based user interface   Grid and cloud enabled   Support for de novo genome assembly   Pre-defined and custom workflows   Advanced visualization   Statistical Analysis

SanGeniX – NGS data analysis suite


Time intensive – Analysis of sequencing data for moderate to large genomes (> 250 MB) takes anywhere between one – three weeks to complete depending on the analysis type.

Computationally intensive – Analysis of sequencing data for moderate to large genomes (> 250 MB) requires hardware with greater than 256 GB RAM.

Resource Intensive – Analysis of NGS data is a multi-step process and requires manual intervention at every step to evaluate data quality and initiate the sequential steps.

Data Interpretation – Results from NGS analysis contains millions of rows and getting to the crux of the analysis is a task that requires large amount of time and efforts.

Key Challenges of NGS data analysis


One platform to do it all

•  One platform to handle all things from Data Management to schematic search to statistics and predictive analysis. •  Statistical Analysis such as SOM, Hierarchical Clustering are already available in HANA and are widely used in

genomic data analysis.

Data Compression

•  HANA compresses the data and the compression is retained even when the data is stored on disk. Genomics data is extremely voluminous and HANA compression can dramatically improve TCO for end customers

Next Generation DB platform

•  HANA as a Next generation DB platform has dramatically improved the processing throughput that can be achieved

SAP HANA – an In-Memory Data Platform for real-time business


Desktop App

3rd Party S

/W

Data Management

Sca

labi

lity

Genomics workbench

API and Plugin

External data source

Postgres Database

Hadoop Cluster

Cloud com.

Add-ons

•  Workflow •  Reporting •  Charting UIs

File system

Workflow engine

Services

Management tool

Customization

Data filter

Statistical tool

  Integration with third part tools and plugins for custom tools/algorithms

  Scalable for deployment on grid cluster or cloud.

  Analysis workflow, reporting and charting interface.

  Scalable data management structure.

SanGeniX – Architecture


SanGeniX Home Page


SanGeniX Predefined Workflow


SanGeniX Custom Workflow


SanGeniX – Running an analysis


SanGeniX Results Dashboard


Summary Business/IT/Scientific Challenges

Technology Value Drivers   Increase the number of projects that an

organization can undertake

  Improve productivity, reduce the time spent on data management

•  SanGeniX platform •  SAP HANA platform •  R Analytical package

•  NGS data analysis is time consuming. Requires anywhere between 1 – 3 weeks for data analysis

•  NGS data analysis is labor intensive and requires analyst involvement at multiple steps.

•  NGS data analysis is computationally intensive.

Process Innovation   Predefined workflows to minimize user

intervention.

  Custom workflows to accommodate lab specific analysis.

  HANA infrastructure for multi-fold increase in data processing speed.

  Visualization dashboard to simplify data interpretation


HANA Competency at Persistent

  HANA App factory for our customers   BWA on HANA   Connectors for various data sources into HANA   Analytics via BO/VI

ShareInsights – BigData Analytics Platform on HANA   A dynamic platform to analyse data and share the insights for events

happening around us   T20 Cricket League dashboard reveals interesting insights on Team/

Player performance against fan conversations   Marquee project was for “Satyamev Javate” show to analyse

sentiments of people per episode

Persistent Overview

SanGeniX on HANA   Persistent LABS team is building a Next Generation Sequencing

(NGS) data analysis application on HANA   Application involves running Burrows-Wheelers algorithm on HANA   ALN step which used to take hours/days to complete now takes only

minutes.

Dealer Enablement Mobile Solution on HANA   Mobility Solution for distributors and suppliers of a Pharma company

to place & track their Drug orders   App supports real-time reporting of drug delivery cycles, statistical

analysis on distributor performance and order execution process using rapid data processing on HANA

Persistent is doing good work in understanding on how HANA applications are built, with a real customer, a pharma giant - Seeker of HANA Solutions at SAP ” “

Expe

rienc

e •  350 Customers

•  3000+ Product releases in last 5 years

•  14 of Top 20 technology companies in the world are our customers

•  23 Years in business

Persistent HANA offering

06 persisten desai · 2013-08-02 · app supports real-time reporting of drug delivery cycles,...

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