président : jean-philippe spano - md, phd paris, france international medical events 19-21 rue...

dent :PrésiJean-Philippe SPANO - MD, PhDParis, France

www.ifods.com

International Medical Events19-21 rue Saint Denis - 92100 Boulogne-Billancourt

Tel. : 00 33 (0)1 41 04 04 04 Fax : 00 33 (0) 1 41 04 04 11

Focus on Consensus and Guidelines for a better Practice

PROGRAM

Comité d’organisation : David Azria, Fabrice Barlesi, Jean-Yves Blay, Anne Charrasse, Rosine Guimbaud, Nicolas Girard, Joseph Gligorov,

Aurélien Gobert, Nathalie Laouti-Savariaud, Thierry Lebret, Philippe Maingon, Jean-Philippe Metges,Françoise Mornex, Hervé Naman, Muriel Paul, Frédérique Penault-Llorca, Edith Perez, Pascal Pujol, Isabelle Ray-Coquard,

Manuel Rodrigues, Jean-Jacques Zambrowski

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International Medical Events (IME)19-21 rue Saint Denis- 92100 Boulogne Billancourt

Web site : www.im-events.com - Email : [email protected]

Organisation CommitteeCONTACT : Valérie CAILLON Tél : + 33 1 41 04 04 04 Fax : +33 1 41 04 04 11 / Email : [email protected]

Travel Information & AccommodationContact : Mathilde MANGIN Tél : + 33 1 41 04 04 04 Fax : +33 1 41 04 04 11 / Email : [email protected]

Dear Friends,

On behalf of the entire IFODS Scientific Committee, it is our honor to announce the second edition of IFODS, which will be held from the 11th to the 13th of JUNE 2019. Following the

success of the first edition in 2018, and thanks to you, your presence, your commitment and your participation, a great number of our fellow oncologists and many of our partners asked us to organize another IFODS. In order to make the meeting even more special, we have decided to change the venue and opt for a more symbolic location: THE “MAISON INTERNATIONALE” AT THE HEART OF THE “CITÉ UNIVERSITAIRE DE PARIS”. This location is consistent with our focus on innovation in the context of French and international collaboration.

Faced with the staggering rise in the incidence of cancer, fortunately offset by outstanding advances in the area of cancer research, both scientific and therapeutic, in which France plays an exemplary role internationally, more than ever we must gather our efforts to fight this disease. Today IFODS is the only French oncology conference which brings together the majority of the relevant French scientific societies (devoted to cancer science and patients) with some other international scientific societies (such as newly for this year AACR and EACR) This year, once again, the “Société Française du Cancer” (SFC) will provide its commitment to IFODS by opening the conference with an extraordinary session on “The Future of Oncology”, organized with the support of scientists, young oncologists and other international scientific societies. IFODS is deeply honored to welcome within its scientific committee and during several sessions the patients and patient’s organizations. They can not only benefit from learning with us during the conference, but can also find a welcoming forum for interaction with healthcare professionals. France maintains a position of excellence and remains a key player in the area of oncology on a glo-bal scale. Scientific exchange is critical for us and the entire field. We would be delighted for you to join us for the Second Edition of IFODS, from the 11th to the 13th of June 2019, at a special venue in Paris. The meeting will include a state of the art update on the rapid evolution in cancer research, biomarkers, and issues related to patient access to newer therapeutic modalities — with an excep-tional panel of French and International Experts in the Oncology field. We thank you in advance for your support and your participation.

Kind regards, Jean-Philippe SPANO, MD, PhD

THE INTERNATIONAL SCIENTIFIC COMMITTEE

AAPRO Matti, Genolier, SwitzerlandAIMARD Lydie, Marseille, FranceALBIGES Laurence, Villejuif, France ANDRE Thierry, Paris, FranceANTOINE Eric-Charles, Neuilly-sur-Seine, France ARMAND Jean-Pierre, Villejuif, FranceASTIER Alain, Paris, FranceAZRIA David, Montpellier, FranceBACHET Jean-Baptiste, Paris, France BARANES Maryline, Paris, France BARLESI Fabrice, Marseille, FranceBELLANGER Agnès, Paris, FranceBLANC Félix, Marseille, FranceBLAY Jean-Yves, Lyon, FranceBONNET Clément, Paris, FranceBENNOUNA Jaafar, Nantes, France BOUILLET Thierry, Paris, FranceCHAHINE Georges, Beyrouth, LibanCHAMPIAT Stéphane, Villejuif, FranceCHARRASSE Anne, Monaco, FranceCHIRAS Jacques, Paris, France CLASSE Jean-Marc, Paris, FranceCLOUGH Krishna, Paris, FranceCOEFFIC David, Reims, FranceCOSCAS Yvan, Paris, FranceDAHAN Muriel, Paris, France DEBIAIS Dominique, Paris, FranceDELALOGE Suzette, Villejuif, FranceDEUTSCH Eric, Villejuif, FranceDICATO Mario, LuxembourgDIELENSEGER Pascale, Paris, FranceDIERAS Véronique, Rennes, France DOHOLLOU Nadine, Bordeaux, FranceDUCREUX Michel, Villejuif, FranceDUTREIX Marie, Paris, FranceESPIÉ Natacha, Paris, France ESPIÉ Marc, Paris, FranceFREYER Gilles, Lyon, FranceGARNIER Georges, Monaco, FranceGILLIET Christophe, Paris, FranceGIRARD Nicolas, Paris, FranceGLIGOROV Joseph, Paris, FranceGOBERT Aurélien, Paris, FranceGONCALVES Anthony, Marseille, FranceGUIMBAUD Rosine, Toulouse, France HANNOUN-LEVI Jean-Michel, Nice, FranceHARDY-BESSARD Anne-Claire, Plerin, FranceHORTOBAGYI Gabriel, Houston, USAHUGUET Florence, Paris, FranceJACQUILLAT Laurence, Paris, France

KAROUI Mehdi, Paris, FranceKRAKOWSKI Ivan, Bordeaux, FranceLAOUTI-SAVARIAUD Nathalie, Biarritz, France LEBBE Celeste, Paris, FranceLEBRET Thierry, Suresnes, FranceLE CESNE Axel, Villejuif, FranceMAINGON Philippe, Paris, FranceMASSARD Christophe, Villejuif, FranceMETGES Jean-Philippe, Brest, FranceMEJEAN Arnaud, Paris, FranceMILANO Gérard, Nice, FranceMORERE Jean-François, Villejuif, FranceMORNEX Françoise, Lyon, FranceMORO-SIBILOT Denis, Grenoble, FranceNAMAN Hervé, Mougins, FranceNAMER Moïse, Nice, FranceNGO Charlotte, Paris, France PAUL Muriel, Créteil, FrancePAUTIER Patricia, Villejuif, FrancePENAULT-LLORCA Frédérique, Clermont-Ferrand, FrancePEREZ Edith, Jacksonville, USAPIERGA Jean-Yves, Paris, FrancePOMEL Christophe, Paris, FrancePUJOL Pascal, Montpellier, FranceRAY-COQUARD Isabelle, Lyon, FranceREBILLON MARYLINE, Paris, France RODRIGUES Manuel, Paris, FranceROBERT Caroline, Paris, FranceROTENBERG Luc, Paris, France ROUPRET Morgan, Paris, FranceROZET François, Paris, FranceSAGHATCHIAN Mahasti, Villejuif, France SAIAG Philippe, Paris, France SAMALIN Emmanuelle, Montpellier, FranceSCOTTÉ Florian, Paris, FranceSHEPHERD Frances, Toronto, CanadaSOUQUET Pierre-Jean, Lyon, FranceSPANO Jean-Philippe, Paris, France SPIELMANN Marc, Paris, FranceSWAIN Sandra, Washington, USATOUBIANA Thierry, Marne-la-Vallée, FranceTOURETTE-TURGIS Catherine, Paris, France UZAN Catherine, Paris, FranceVAN CUTSEM Eric, Leuven, BelgiumVANNIER Marie-Paule, Paris, France VIEILLARD Marie-Hélène, Lille, France VINCENT-SALOMON Anne, Paris, FranceWASSERMANN Johanna, Paris, France ZAMBROWSKI Jean-Jacques, Paris, France

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THE INTERNATIONAL SPEAKERS COMMITTEE

ALBIN Nicolas, Rouen, France ALLORY Yves, Créteil, France ANDRE Fabrice, Villejuif, FranceANDRÉ Thierry , Paris, FranceASSAKER Richard, Lille, FranceASTIER Alain, Paris, FranceAZRIA David, Montpellier, FranceBACHET Jean-Baptiste, Paris, FranceBAEHNER Rick, San Francisso, USBAROUDJIAN Barouyr, Paris, FranceBARRANGER Emmanuel, Nice, FranceBEDDOCK Arnaud, Paris, FranceBERTOLUS Chloé, Paris, Fran≤ceBOIGE Valérie, Villejuif, FranceBOSSI Alberto, Villejuif, FranceBOUDALI Lotfi, Saint-Denis, France BOUILLET Thierry (TBC)BOURGIER Céline, Montpellier, FranceBREILH Dominique, Bordeaux, FranceBRUNET POSSENTI Florence, Paris, FranceCAPPUZZO Frederico, Ravenna, ItalyCHAHINE W. Georges, Beirut, LibanCHAMPIAT Stéphane, Villejuif, FranceCHAPUT Nathalie, Villejuif, France (TBC)CHARBONNIER-BEAUPEL Fanny, Paris, FranceCLASSE Jean-Marc, Paris, FranceCOGOS KatiaCOMPERAT Eva, Paris, France CONFORTI Rosa, Paris, FranceCOURAUD Sébastien, Lyon, FranceDAHAN Muriel, Paris, FranceD’ARRIPE-LONGUEVILLE Fabienne, Nice, France (TBC)DAUCHY Sarah, Villejuif, France (TBC)DE KONING Harry, Glasgow, ScotlandDE LA MOTTE ROUGE Thibault, Paris, FranceDEPIL Stéphane, Lyon, FranceDESCOTES Jean-Marc, Paris, FranceDESPIAU Frédéric, Toulouse, FranceDIPALMA Mario, Villejuif, FranceDOUILLARD Jean-Yves, Lugano, SwitzerlandDUBOIS Eliane, Dijon, FranceDUFFAUD Florence, Marseille, FranceDUFRESNE Armelle, Lyon, FranceELALAMY Ismaïl, Paris, FranceFAIDERBE Sylvie, Paris, France FELIP Enriqueta, Barcelona, SpainFOY Jean-Philippe, Paris, France FRENEL Jean-Sébastien, Nantes, FranceGAUTIER Christelle, Paris, France (TBC)GORRY Philippe, Bordeaux, FranceGUIMBAUD Rosine, Toulouse, FranceHARDY BESSARD Anne-Claire, Plérin, FranceHAZIZA Jean-Luc, Paris, FranceHUGUET Florence, Paris, FranceIDBAIH Ahmed, Paris, FranceIFRAH Norbert, Angers, France IRANI Jacques, Kremlin Bicêtre, FranceITALIANO Antoine, Bordeaux, France KAASA Stein, Trondhein, NorwayKUHNOWSKI Frédérique, Paris, France (TBC)LARGHERO Jérome, Paris, FranceLASSOUED Donia, Paris, France

LAUNAY VACHER Vincent, Paris, FranceLE GUYADER Maud, Saint-Etienne, FranceLEBRET Thierry, Suresnes, FranceLEDOS Christine, Paris, France LE SAUX Olivia, Lyon, France LESUEUR Paul, Caen, FranceLEVERGER Guy, Paris, France (TBC)LIEVRE Astrid, Rennes, FranceLOUVET Christophe, Paris, FranceMAINGON Philippe, Paris, FranceMALKA David, Villejuif, FranceMASSARD Christophe, Villejuif, FranceMEHIZ Sabrina, Lausanne, Switzerland MEJEAN Arnaud, Paris, FranceMETZ Carole, Paris, FranceMEUNIER Françoise, Brussels, BelgiumMILANO Gérard, Nice, FranceMORARDET Laetitia, Paris, FranceMONIOT Valérie Anne, Paris, France NOVELLO Sylvia, Turin, ItalyPAGES-LAURENT Cécile, Paris, FrancePAUL Muriel, Créteil, FrancePEEPER Daniel, Leiden, NetherlandsPENEL Nicolas, Lille, FrancePEREZ Edith, Jacksonville, USAPEROL Maurice, Lyon, FrancePERRIER Lionel, Genova, SwitzerlandPIERRE Michel, Rouen, FrancePLAIS Henri, Paris, FranceQUIDET Mathilde, Lille, France RAMA Nicole, Paris, FranceRAY-COQUARD Isabelle, Lyon, FranceREBILLON Maryline, Paris, FranceREMON Jordi, Barcelona, Spain RICHARD Lee, London, UKROBERT Jacques, Paris, FranceRODIN Gary, Toronto, Canada RODRIGUES Manuel, Paris, FranceROUPRET Morgan, Paris, FranceROUTIER Emilie, Villejuif, FranceSAADA-BOUZID Esma, Nice, FranceSFERRAZZO Karine, Marseille, France SPANO Jean-Philippe, Paris, FranceSUKADI Ida, Paris, France TAQUET Anne, Paris, France (TBC)TERRASSIER Dominique, Paris, France THIBAULT Constance, Paris, FranceTHUREAU Sébastien, Rouen, FranceTOLEDANO Valérie, Paris, France TOURNIGAND Christophe, Paris, FranceTREDAN Olivier, Lyon, FranceUZAN Catherine, Paris, FranceVASSAL Gilles, Villejuif, France VIGNOZZI Annick, Villejuif, FranceWATERFALL Joshua, Paris, FranceWISLEZ Marie, Paris, FranceYCHOU Marc, Montpellier, FranceZAANAN Azize, Paris, FranceZEHOU Ouidad, Paris, France

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Conférence Multidisciplinaire d’oncologie / Multidisciplinary Oncology Conference / Consensus and Guidelines for a better practiceSCIENTIFIC SYMPOSIUM ON PROGRAM

Scientific Symposia are sessions during which some of the world best experts will, upon invitation, address different issues related to a specific topic. Each scientific symposium will end with a round

table discussion and Q & A with the audience.

iTHE FUTURE OF ONCOLOGY (Basic Science)/LE FUTUR DE L’ONCOLOGIERoom ADENAUER • 02:30-04:30 PMUnder the aegis of SFC, EACR and AACRPresident: Manuel Rodrigues Moderators: Jean-Pierre Armand, Marie Dutreix, Aurélien Gobert, Gérard Milano, Jacques Robert, Jean-Philippe SpanoSpeakers:• 02:30-03:00 PM: Future of research: Daniel Peeper (EACR & Cancer Research UK)• 03:00-03:30 PM: Future of cancer genomics: Joshua Waterfall (Group leader translational Research Department, Institut Curie)• 03:30-04:00 PM: Future of immunotherapy: Stéphane Depil, Senior Vice President of R&D, Cellectis• 04:00-04:30 PM: Financial impact of innovation in Oncology: Lionel Perrier (Head of innovation and health strategies department /Léon Bérard/Lyon)4:30-5:00 PM: pause / visite sur les stands / break

iAWARDS CEREMONYRoom ADENAUER • 05:00-06:00 PM• THESIS on behalf of AERIO & SFC• CLAUDE JACQUILLAT on behalf of SFCHonorary Presidents: Edith Perez & Sandra Swain i PHARMACIST SESSION/ SESSION DES PHARMACIENSRoom GULBENKIAN • 02:30-04:30 PMPresidents: George Garnier & Muriel PaulnThe new therapeutic decor: old revisited and contemporary blend togetherModerators: Muriel Paul, Georges Garnier• 02:30-02:45 PM: Repositioning of old drugs in oncology: a challenge. Alain Astier • 02:50-03:05 PM: ImmunoT: more and more associations, inventory and consequences. Esma Saada-Bouzid

• 03:10-03:25 PM: ImmunoT: the need to identify the right candidates for the host's level. Gerard Milano • 03:30-03:45 PM: The CAR T cells: which drug is it? Muriel Paul • 03:50-04:05 PM What role of the hospital pharmacist in the management of the CAR-T cells distribution circuit. Fanny Charbonnier-Beaupel/Carole Metz• 04:10-04:25 PM ATMP at the academic level: the example of the Meary Center for Cell and Gene therapy. Jérôme Larghero

4:30-5:00 PM: pause / visite sur les stands / break

èoPOSTERS SESSION

iNURSE SESSION/ SESSION INFIRMIÈRESRoom DAVID-WEILL • 02:30-05:00 PMUnder the aegis of AFICPresidente: Pascale DielensegerModérateurs : Pascale Dielenseger, Frédéric Despiau, Eliane Dubois• 02:30 PM: Introduction : « Guidelines et Bonnes Pratiques dans la prise en charge infirmière des effets secondaires….. » : Pascale Dielenseger, Cadre Supérieure de Santé, Présidente AFIC• 02:35 PM: Dans les traitements par chimiothérapie : Eliane Dubois, Infirmière CLCC, AFIC• 02:55 PM: Dans les traitements par TKI : Frédéric Despiau, Cadre Supérieur de Santé, CLCC, AFIC• 03:15 PM: Dans les traitements par Immuno-thérapie : Nicole Rama, Chargée de Mission AFIC• 03:35 PM: Dans les traitements par Radiothérapie / exemple des radiodermites : Annick Vignozzi, Cadre de Santé • 03:55 PM: Recherche en soins / Evidence best Nursing : Sabrina Mehiz, Chargée de mission AFIC• 04:25 PM: Comparatifs de prise en charge selon les traitements d’un « même » effet secondaire : Oncologue, TBC• 04:55 PM: Conclusion : Pascale Dielenseger, Présidente AFIC

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iCONSENSUS AND GUIDELINES ON BREAST CANCER (1)

INNOVATION: ACCELERATE OR SLOW DOWN

Room ADENAUER • 09:00-12:30 AMUnder the aegis of St Paulwith the institutional support of GUERBET Presidents: Moïse Namer & Joseph GligorovSpeakers: Céline Bourgier, Jean-Marc Classe, Rosa Conforti, Véronique Dieras, Edith Perez, Luc Rotenberg, Marc Spielmann, Sandra Swain, Catherine Uzan, Johanna Wassermann

nPart I: Accelerate • 09:00-10:30 AM: Locoregional treatment and evaluation Chair Persons: Johanna Wassermann, Jean-Marc Classe• 09:00-09:25 AM: Tomosynthesis and angio-mamography: the need of the MRI? Luc Rotenberg• 09:30-09:55 AM: Sentinel lymph node for every EBC: enlarging the indications? Catherine Uzan• 10:00-10:25 AM: Deescalate radiotherapy for some EBC: a standard or an option? Céline Bourgier

• 10:30-11:00 AM: Pause/Visite sur les stands/Break

• 11:00-12:30 AM: Systemic therapies Chair Persons: Rosa Conforti, Marc Spielmann• 11:00-11:25 AM: PARP inhibitors for BRCAmut patients: really usefull in MBCs? Veronique Dieras• 11:30-11:55 AM: PIK3CAmut: does it really matter for treatment strategies in ER+ MBCs ? Sandra Swain• 12:00-12:25 AM: Immune therapy for breast cancers: revolution or evolution in MBCs? Edith Perez

oPOSTERS SESSIONh12:30 AM-2:00 PM

ROOM ADENAUER • BREAST CANCER HIGHLIGHTS FITI * SESSION (International Meetings Update) With the support of PFIZER

Room DAVID-WEILL • ÇÇ LUNCH/DEBATE ÇÇ With the support of TESARO

iCONSENSUS AND GUIDELINES ON BREAST CANCER (2)

INNOVATION: ACCELERATE OR SLOW DOWN

Room ADENAUER • 02:00-03:00 PMUnder the aegis of St Paul & SFMPP

Presidents: Moïse Namer & Joseph GligorovSpeakers: Georges Chahine, Suzette Delaloge, Gilles Freyer, Edith Perez, Jean-Yves Pierga, Pascal Pujol, Sandra Swain, Frederique Penault-Llorca

nPart II: Slow Down

• 02:00-03h00 PM: Molecular signatures for Breast Cancers: French specificity or lack of expertise?Chair Persons: Georges Chahine, Pascal Pujol

Round table

• 02:00-02:15 PM: French HAS conclusions for molecular signature place in EBC/ Frederique Penault-Llorca

• 02:15-02:30 PM: AJCC 8th edition and ASCO guidelines for molecular signatures: Sandra Swain

• 02:30-02:45 PM: French Experience with various molecular signatures: Suzette Delaloge

• 02:45-03:00 PM: Round table discussion with Jean-Yves Pierga, Gilles Freyer, Edith Perez

iOVARIAN CANCERS: THE NEW THERAPEUTIC APPROACHES TO KNOW/CANCERS DE L’OVAIRE : LES NOUVELLES APPROCHES THÉRAPEUTIQUES À CONNAÎTRE

Room ADENAUER • 03:00-04:30 PMUnder the aegis of SFCO

Presidents: Jean-Marc Classe, Isabelle Ray-Coquard

Chair Persons: Jean-Marc Classe, Isabelle Ray-Coquard et Olivia Le Saux• 03:00-03:20 PM: What's new from Chicago for ovarian cancer? Thibault de la Motte rouge• 03:20-03:40 PM: What's new from Chicago for endometrial and cervical cancer? Jean-Sébastien Frenel• 03:40-04:00 PM: The important points for surgery in ovarian cancer (with the rationale of chrono etc.). Jean-Marc Classe• 04:00-04:20 PM: Immunotherapy and PARP inhibitor in ovarian cancer where we are? Olivia Le Saux• 04:20-04:30 PM: Resistance to PARP inhibitor, Mecanisms and how to restore? Manuel Rodrigues

• 04:30-04:35 PM: Take home message. Isabelle Ray-Coquard, Jean-Marc Classe

WEDNESDAY 12th JUNE

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iTHE BIOSIMILARS: THE POINT OF VIEW OF THE PATIENTS/LES BIOSIMILAIRES : LE POINT DE VUE DES PATIENTSRoom ADENAUER • 05:00-06:30 PM Patients Associations : Europa Donna, Life is RosePresidents: Maryline Baranes, Muriel Dahan, Dominique Debiais, Natacha Espié, Gilles Freyer, Nathalie Laouti-Savariaud, Jean-Jacques Zambrowski

• 5:00-5:45 PM: The trauma of cancer: psychological consequences and therapeutic interventions. Gary Rodin, Jean-Luc Haziza, Maryline Baranes

• 5:45-6:30 PM: Round Table

Chair Person: Jean-Jacques Zambrowski Room ADENAUER • 06:30-07:30 PM w Soirée Grand Témoin - Luc FerryTroisième révolution industrielle, intelligence artificielle et transhumanisme

u COCKTAIL DÎNATOIRE/DINER COCKTAIL • 07:30-09:30 PM

iCONSENSUS AND GUIDELINES ON GI TUMORSRoom GULBENKIAN • 09:00-12:30 AMUnder the aegis of Prodige Group, UNICANCER GI, GERCOR & FFCDPresidents: Pierre Michel & Emmanuelle Samalin

1/nColorectal and OesoGastric SessionChair Persons: Christophe Louvet, Florence Huguet• 09:00-09:15 AM: Adjuvant standard for colon cancer in 2019 and future perspectives. Thierry André• 09:20-09:35 AM: Metastatic BRAF mutated colorectal cancer. Emmanuelle Samalin• 09:40-09:55 AM: Immunotherapy in oesophagel and gastric cancers? Jean-Philippe Metges• 10:00-10:15 AM: Cancer of the anal canal. Astrid Lievre• 10:20-10:35 AM: Adenocarcinoma in metastatic stomach cancer setting. Azize Zaanan

2/nBiliary & Pancreatic SessionChair Persons: Valérie Boige, Rosine Guimbaud

• 11:00-11:15 AM: Pancreatic cancer in adjuvant situation. The point in 2019. Jean-Baptiste Bachet• 11:20-11:35 AM: Hepatocellular carcinoma. Jean-Frédéric Blanc• 11:40-11:55 AM: Biliary carcinomas: the point in 2019. David Malka• 12:00-12:15 AM: Circulating DNA in GI cancer: what’ s new ? Marc Ychou• 12:20-12:30 AM: Take home message/discutant. Christophe Tournigand

10:30-11:00 AM: pause / visite sur les stands / break

h12:30AM-2:00 PM

Room GULBENKIAN • ÇÇ LUNCH/DEBATE ÇÇ PAN TUMORS With the support of PIERRE FABRE

iCONSENSUS AND GUIDELINES ON DERMATOLOGYRoom GULBENKIAN • 02:00-03:30 PM With the Institutional support of BMSPresidents: Barouyr Baroudjian & Cécile Pages-Laurent

Chair Persons: Philippe Saiag, Donia Lassoued

• 02:00-02:15 PM: Update in melanoma management : what are the strong ideas and the ways to improve? Philippe Saiag• 02:20-02:35 PM: What biomarkers to guide our prescriptions in melanoma ? Ouidad Zehou• 02:40-02:55 PM: Adjuvant treatments for melanoma: which patients? What benefits? What risks? Florence Brunet Possenti• 03:00-03:15 PM: Can we stop anti-melanoma treatments in patients in complete remission? Emilie Routier• 03:15-03:30 PM: Checkpoint inhibitors in oncodermatology, beyond melanoma. Cécile Pagès-Laurent

iDUETS SESSION NTRK GENE FUSION: "FROM BENCH TO BEDSIDE"/SESSION SPÉCIFIQUE BIO- MARQUEURS: "GÈNE DE FUSION NTRK"Room GULBENKIAN • 03:30-04:30 PMExperts: Edith Perez, Frédérique Penault-LlorcaChair Persons: Sandra Swain, Jean-Michel Hannoun-Levi



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iCONSENSUS AND GUIDELINES ON UROLOGYRoom DAVID-WEILL • 09:00-12:30 AM Under the aegis of AFUChair Persons: David Azria, Thierry Lebret, Arnaud Méjean, Morgan Roupret

nNodal involvement in onco-urology • 09:00 AM: Physiopathology of nodal involvement Eva Comperat• 09:15 AM: Discussion around 3 clinical cases• 09:30 AM: Prostate : Thierry Lebret• 09:h45 AM: Kidney : Arnaud Mejean• 10:15 AM: Bladder : Morgan Roupret

• 10:30 AM: Experts: Alberto Bossi (radiation oncologist) - Aurélien Gobert (medical oncologist) - Jacques Irani (Urology)

10:45 AM: pause / visite sur les stands / break

oPOSTERS SESSION

11:15-12:30 AM: SYMPOSIUMWith the support of RECORDATInSystemic immunotherapy in renal and bladder neoplasms: an update Chair Person: Thierry Lebret• Kidney : Arnaud Mejean• Non muscle invasive bladder cancer: Morgan Roupret• Metastatic muscle invasive bladder cancer +: Constance Thibault


h12:30AM-2:00 PM

iCONSENSUS AND GUIDELINES ON RADIOTHERAPY

Room DAVID-WEILL • 02:00-04:30 PM Under the aegis of SFRO

Presidents: David Azria, Florence Huguet, Philippe Maingon, Françoise Mornex• 02:20-02:35 PM: IO-RT combination for NSCLC: State of the art in 2019. Françoise Mornex• 02:40-03:15 PM: Individual radiosensitivity for tumors: Potential clinical implementation in 2019 ? David Azria• 03:20-03:55 PM: SFRO: Present and Future. Philippe Maingon• 04:00-04:30 PM: Role of SABR in the therapeutic management of Oligometastasis. Florence Huguet


iEMERGING AND CURRENT THERAPEUTIC APPROACHES IN HEAD AND NECK CANCER (HPV+ and HPV-)/LES APPROCHES THÉRAPEUTIQUES ÉMERGENTES ET ACTUELLES DANS LE CANCER DE LA TÊTE ET DU COU (HPV+ et HPV-)Room DAVID-WEILL • 05:00-06:30 PMUnder the aegis of AERIO and the SFJRO With the Institutional support of MSD

Presidents: Felix Blanc, Florence Huguet, Paul LesueurModerators: Chloé Bertolus, Philippe Maingon

• 05:00-05:15 PM: The use of proton therapy in the treatment of head and neck cancers by Arnaud Beddok, assistant, boarded by Professor Philippe Maingon

• 05:20-05:35 PM: Therapeutic De-intensification for patients with head and neck HPV positive cancers by Maud Le Guyader, Intern in Nice boarded by Professor Florence Huguet

• 05:40-05:55 PM: HPV Vaccine, current knowledge and pratices. Jean-Philippe Foy boarded by Chloé Bertolus

• 06:00-06:15 PM: Immunotherapy or chemotherapy for advanced H&N cancer: which treatment when? Henri Plais boarded by Esma Saada-Bouzid

• 06:20-06:30 PM:Take home message, Philippe Maingon

THURSDAY 13th JUNE


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iCONSENSUS AND GUIDELINES ON LUNG CANCER (1)

Room ADENAUER • 09:00-12:30 AMUnder the auspices of our respective groups: IFCT, Oncology Group/SPLF Presidents: Sébastien Couraud, Nicolas Girard, Françoise Mornex, Denis Moro-Sibilot, Pierre-Jean SouquetnPrecision medicine strategies: key questions in 2019Chair Persons: Fabrice Barlesi, Frances Shepherd, Denis Moro-Sibilot• 09:00 AM: EGFR+ NSCLC: when to use third generation TKIs? Frances Shepherd • 09:30 AM: ALK+ NSCLC: is rebiopsy worth to sequence TKIs? Sylvia Novello• 10:00 AM: MET+ NSCLC: towards next generation inhibitors? Frederico Cappuzzo• 11:00 AM: HER2+ NSCLC: how to use available targeted agents? Nicolas Girard• 11:30 AM: RET+: what are the ongoing trials? Marie Wislez• 12:00 AM: special session on lung cancer screening. Richard Lee10:30-11:00 AM: pause / visite sur les stands / break

oPOSTERS SESSIONh12:30AM-2:00 PM: adjourn

iATELIER SPORT & CANCER Room ADENAUER • 02:00-04:30 PMUnder the aegis of CAMIPresidents: Thierry Bouillet & Jean-Marc Descotesn Loi Sport sur Ordonnance : de l’inclusion au remboursement ? • 14h00 : Introduction. Thierry Bouillet (Co-fondateur et Président de la CAMI Sport & Cancer)• 14h15 : Table ronde - Quelles effets de la thérapie sportive ? - En oncologie : Catherine Uzan (oncologue, Hôpital Pitié-Salpêtrière) (TBC) - En hématologie : Frédérique Kuhnowski (hématologue, Institut Curie) (TBC) - En pédiatrie : Plan A : Guy Leverger (hématologue, Hôpital Trousseau) (TBC) • 15h00 : Table ronde - Quels freins et leviers à la pratique ? - Sarah Dauchy (psychiatre, Gustave Roussy) (TBC) - Fabienne d’Arripe-Longueville (psychologue, Université Nice Sophia Antipolis) (TBC) - Anne Taquet (action pour les malades, Ligue Nationale contre le Cancer) (TBC)

• 15h45 : Table ronde - Quelle évaluation médico-économique de la thérapie sportive ? - Christelle Gautier (Cheffe de projet Stratégie Nationale Sport Santé, Direction des sports) (TBC) - 1 représentant du Ministère de la Santé - 1 représentant de la CNAM

• 16h15 : Conclusion. Jean-Marc DESCOTES (Co-fondateur et Directeur Général de la CAMI Sport & Cancer)

• 16h30 - FIN

h05:00-05:30 PM

oPOSTERS SESSION

iPRIVATE ONCOLOGIST SESSION/ LES ONCOLOGUES PRIVÉSRoom GULBENKIAN • 09:00-10:30 AMUnder the aegis of CROL & SOFOMPresidents: Lydie Aimard, Eric-Charles Antoine, Dominique Breilh, David Coeffic, Yvan Coscas, Muriel Dahan, Nadine Dohollou, Philippe Gorry, Hervé Naman, Thierry Toubiana

• 09:00-09:20 AM: Access to therapeutic innovations in Europe: Philippe Gorry• 09:20-09:40 AM: The "CAQES process in France: what else?”: Dominique Breilh

• 09:40-10:00 AM: Contributions of the new health law to facilitate access to innovations: Muriel Dahan

• 10:00-10:20 AM: The legal aspect of inequalities of access to innovation: Karine Sferrazzo

• 10:20-10:30 AM: Discussion



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iUNIVERSITÉS DES PATIENTS :LA CHORÉGRAPHIE DES ANNONCES EN CANCÉROLOGIE SELON UNE PERSPECTIVE PATIENTRoom GULBENKIAN • 11:00-12:30 AMPatients Associations : Université des Patients (From Sorbonne University)Présidentes : Maryline Rebillon, Professeur associé, Sorbonne Université, Marie-Paule Vannier, MCF, Ingénieur pédagogique dans le DU «Mission d’accompagnant du parcours patient en cancérologie», Université des patients-Sorbonne Université.Intervenantes : Sylvie Faiderbe, Christine Ledos, Valérie-Anne Moniot, Ida Sukadi, Dominique Terrassier, Valérie Toledano, patientes expertes, Université des Patients – Sorbonne Université.Discutants invités : médecin oncologue, psycho oncologue, communicant. (à préciser)

• 11:00 AM: Temps 1 : Les annonces du répertoire de la cancérologie – l’annonce du cancer, la récidive, la rémission: point de vue, rôle et place du patient expert / patient partenaire pour mieux entendre ces annonces.• 11:30 AM: Temps 2 : Les annonces « orphelines » en cancérologie - du doute à l'annonce, l'annonce aux proches et aux aidants, l'annonce de la guérison : point de vue, rôle et place du patient expert / patient partenaire pour favoriser leur visibilité et leur prise en compte dans le parcours de soin.• 12:00 AM: Temps 3 : Les apports d’une perspective patient: synthèse et mise en débat.

h12:30AM-2:00 PM

iSUPPORTIVE CARE & SOCIO-AESTHETICS SESSION/SESSION SOINS DE SUPPORT & SOCIO-ESTHÉTIQUESRoom GULBENKIAN • 02:00-04:30 PMUnder the aegis of AFSOS Presidents: Matti Aapro, Ivan Krakowski, Vincent Launay-Vachet, Mahasti Saghatchian, Florian Scotté

• 02:00-02:25 PM: Siog combined session (thrombosis prophylaxis and frailty). Ismaïl Elalamy• 02:30-02:55 PM: Monitoring - PRO. Mario Dipalma

• 03:00-03:25 PM: Survivorship program. Françoise Meunier, Vice Président of FEAM• 03:30-03:55 PM: Specific toxicities: Immunothérapie case vignettes. Stéphane Champiat• 04:00-04:25 PM: Integration palliative care. Stein Kaasa


iIMMUNOTHERAPY SESSION: A TRANSVERSAL APPROACH IN ONCOLOGY / SESSION IMMUNOTHERAPIE : UNE APPROCHE TRANSVERSALE EN ONCOLOGIERoom GULBENKIAN • 05:00-06:00 PMChair Persons: Sandra Swain, Frédérique Penault-LlorcaSpeakers: Nathalie Chaput, Ahmed Idbaih, Edith Perez • 05:00-05:10 PM: Immunology breaking news: Nathalie Chaput• 05:10-05:20 PM: Rational for combination in immunology field: Edith Perez• 05:20-05:30 PM: Neuro oncology: Ahmed Idbaih• 05:30-05:40 PM: Immunocompromised cancer Patients: Aurélien Gobert• 05:40-05:50 PM: Perspectives and patients monitoring: Stéphane Champiat• 05:50-06:00 PM: Discussion

iEARLY CLINICAL TRIALS: HOW, WHO, WHERE CAN PATIENTS GET ACCESS?/ ESSAIS CLINIQUES PRÉCOCES: COMMENT, QUI, OÙ LES PATIENTS PEUVENT-ILS AVOIR ACCÈS ?Room DAVID-WEILL • 09:00-10:30 AMPresidents: Jean-Yves Blay & Christophe MassardRound table with: Lofti Boudali (ANSM), Gilles Vassal, Antoine Italiano, Katia Cogos (patiente)

• 09:00-09:10 AM: nINTRODUCTION: Perspective of the program and issues and presentation of the speakers. Jean-Yves Blay, Christophe Massard• 09:10-09:25 AM: 1-The new approaches and solutions of the ANSM to take up the challenge of the attractiveness of France in the early stages! Lotfi Boudali or Nicolas Albin (ANSM Product Management Oncology Hematology)

ROOM GULBENKIAN • IMMUNOTHERAPY HIGHLIGHTS FITI* SESSION (International Meetings Update) With the support of MSD

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• 09:30-09:45 AM: 2-How is pediatric oncology organized to accelerate access to clinical trials? Gilles Vassal • 09:50-10:05 AM: 3-Genomic screening an accelerator for recruitment in the early stages? Antoine Italiano • 10:10-10:25 AM: 4-The AcSé program 6 years already... Assessment and prospects! (TBD) 10:30-11:00 AM: pause / visite sur les stands / break

oPOSTERS SESSION

iCONSENSUS AND GUIDELINES ON SARCOMARoom DAVID-WEILL • 11:00-12:30 AMUnder the aegis of GSF-GETOChair Persons: Jean-Yves Blay, Axel Le Cesne• 11:00-11:15 AM: A) Guidelines update : Florence Duffaud gist bone soft tissue

• 11:20-11:35 AM: New drugs and new trials in GIST: new interesting drugs in sarcoma. Nicolas Penel

• 11:40-11:55 AM: Immunotherapy in sarcoma: next question? Armelle Dufresne

• 12:00-12:15 AM: Why did announce fail? lessons learned: Axel Le Cesne

• 12:20-12:30 AM: B) General discussion

h12:30AM-2:00 PM

Room DAVID-WEILL • ÇÇ LUNCH/DEBATE ÇÇ

With the support of ASTRA ZENECA

Actualités et perspectives d'avenir dans la prise en charge des CBNPC

iCONSENSUS AND GUIDELINES ON LUNG CANCER (2)

Room DAVID-WEILL • 02:00-03:30 PMUnder the auspices of our respective groups: IFCT, Oncology Group/SPLF Presidents: Fabrice Barlesi, Sébastien Couraud, Nicolas Girard, Françoise Mornex, Frances Shepherd, Pierre-Jean Souquet

nImmunotherapy: one fits all or need for customization?Chair Persons: Pierre-Jean Souquet, Nicolas Girard, Maurice Perol• 02:00 PM: Immunotherapy as a standard for first-line treatment: single agent or combination? Maurice Perol • 02:30 PM: Is there still a room for PD-1/PD-L1 inhibition beyond first-line? Jordi Remon

• 03:00 PM: Biomarkers beyond PD-L1: what is the true evidence in NSCLC? Fabrice Barlesi

iRPC: INTERACTIVE WEBCONFERENCE MULTIDISCIPLINARY BOARD / BONE METS: THE BEST LOCAL TREATMENT FOR A BETTER OUTCOM / RCP: WEB CONFERENCES INTERACTIVES, RÉUNION MULTIDISCIPLINAIRE/Room DAVID-WEILL • 03:30-04:30 PM

Under the aegis of GEMO

nLa prise en charge des métastases osseusesChair Persons: Nicolas Girard, Jacques Chiras, Marie-Hélène Vieillard

From 3 clinical situations:

• 03:30-03:45 PM: Episode 1: Fracture... did you say fracture? Laetitia Morardet

• 03:50-04:05 PM: Episode 2: Decompression of Friday night. Mathilde Quidet, Richard Assaker

• 04:10-04:25 PM: Episode 3: Oligometastatic Bone Disease: Looking Ahead. Sébastien Thureau



- Abstracts have to be submitted electronically and in English- Abstracts received after the deadline (April 15th, 2019) will not be considered- Supply as much information as possible: the precise subject of study, methods used where appropriate, summary of results obtained, conclusion- As it is assumed that original work will be presented, no bibliographic references are necessary- Selected abstracts will be published in the abstract book exactly as you submitted it. Therefore, proofreading is essential, no modification will be possible after submission.- Your abstract should not contain accents or any other invalid character, which would not be part of the English alphabet.- Your abstract’s text should not exceed 3,000 characters (excluding spaces)- The main author (presenter) confirms that all authors are aware of and agree to the content of the abstract and support of the data presented. By submitting his abstract, the author allows the IFODS to publish and distribute or sell his abstract as part of the Abstract Book, which may be distributed on paper.- All selected abstracts will be published in the abstract book. Papers accepted for IPOSTER presentation will be displayed during poster sessions.- Acceptance or rejection of the paper by the Scientific Committee will be notified by email to the main author (presenter) by April 26th, 2019- Only persons whose registration is complete will be able to present their abstracts- IPOSTERS will be awarded or encouraged: a special jury will select the three best posters and their authors will receive IFODS Poster Award and a cheque of 500E each.

Registration (Allows to access all satellite meetings of the IFODS)

REGISTRATION FEES (in Euros) Regular Registration

From Nov. 15th 17 to March. 15th 2019 p 500 e

From March. 16th 2019 and on site p 600 e

WAY OF REGISTRATIONOnline Registration: secure online registration and payment by credit card via the website www.ifods.comRegistration will be validated only with payment by credit card (Visa, Mastercard).Registration Form sent by Fax or Mail:you can download the registration form on the website and send it duly completed to the Organisation Committee.Registration will be validated only with payment attached or credit card information completed.Cancellation PolicyBefore April 2nd, 2019: 50% cancellation feesFrom April 3rd, 2019: no refund

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International Medical Events (IME )19-21 rue Saint Denis - 92100 Boulogne-Billancourt - France - Web site : www.im-events.com - Email: [email protected] CommitteeContact : Valérie CAILLON : Tel : + 33 1 41 04 04 04 - Fax : +33 1 41 04 04 11 Email: [email protected] Information & AccommodationContact : Mathilde MANGIN : Tel : + 33 1 41 04 04 04 - Fax : +33 1 41 04 04 11Email: [email protected]

SUBMISION GUIDELINES

AbstractsSubmission

Deadline: April 15h,

2019ABSTRACT


PCOMedical Department

[email protected]. : 00 33 (0)1 41 04 04 04 / Fax : 00 33 (0) 1 41 04 04 11

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EN VOITUREEn arrivant en voiture : Empruntez le Périphérique Sud, sortie Porte d’Orléans ou Porte de Gentilly. L’entrée réservée aux voitures est située au 17 bd Jourdan uniquement pour les clients. Payant au-delà de 5 voitures.Le public doit être dirigé vers le parking Charlety (8 minutes à pied de la maison internationale)

EN TRANSPORTS EN COMMUNEn arrivant en RER : RER B, arrêt Cité UniversitaireEn arrivant en métro : Métro ligne 4, station Porte d’OrléansEn arrivant en tramway : T3, arrêt Cité Universitaire

Maison Internationale

CONGRESS LOCATION CITY MAISON INTERNATIONALE


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GLOBAL MEETINGS PROGRAM - TICKETS PURCHASINGThe Discount Agreement will be for travel between June 4th through June 20th, 2019.

To benefit from these special offers, link up with http://globalmeetings.skyteam.com and quote the Identifier Code 34 283 AF Tickets purchased on the following Carriers are eligible for the SkyTeam Global Meetings programme:

Aeroflot, Aerolíneas Argentinas, Aeroméxico, Air Europa, Air France, Alitalia, China Airlines, China Eastern, China Southern, Czech Airlines, Delta Air Lines, Kenya Airways, KLM Royal Dutch Airlines, Korean Air, Middle East Airlines, Saudia, TAROM,

Vietnam Airlines and Xiamen Air.

To book your travel now, visit www.skyteam.com/GlobalMeetings and enter your Event ID, 34 283 AF

AIR FARE DISCOUNT - Event ID : 34 283 AFSkyTeam Global Meetings Agreement - This Agreement is entered into by and among member airlines of the SkyTeam Alliance and EQUATOUR. The airlines of SKYTEAM, Official Alliance Network for the IFODS 2019, offer attractive airfares for participants.

SKYTEAM comprises 19 leading international airlines serving 1000 destinations in 187 countries with over 15 000 flights daily.

Whether you are the organiser or the participant, the Global Meetings Program allows you to benefit from the expertise of SkyTeam’s network covering over 1,000 destinations worldwide. Via the online portal, not only can participants obtain discounted travel, but fl ights and connections are made more convenient. Organisers can also take advantage of an online solution especially designed to meet their needs, including a productivity reward program. Additionally, we provide you with a communications kit and one point of contact to help manage your event. Visit our website www.skyteam.com/globalmeetings

Through this site you can also access the schedules of all SkyTeam partners to plan your flights on the airline of your choice.

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président : jean-philippe spano - md, phd paris, france international medical events 19-21 rue...

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