zeiss axio scan · calibration guarantees reproducible output power levels for each wavelength. you...

ZEISS Axio Scan.Z1Your Fast and Flexible Slide Scanner for Fluorescence and Brightfield

Product Information

Version 2.0

2

Digitize your specimens with Axio Scan.Z1 – the reliable, reproducible way to

create high quality virtual slides. The excellence of the components guarantees

the excellence of the image – just as you would expect from a ZEISS device.

And the quality of the virtual slides remains consistently high, even when

capturing fluorescence images at unprecedented speed.

This outstanding image quality is based on plan-apochromatic objectives with

numerical aperture up to 0.95. Highly automated and very simple to operate,

Axio Scan.Z1 tackles the most demanding research tasks as easily as it handles

your routine work, controlled by familiar ZEN software from ZEISS: operation is

designed specifically for the workflow of capturing virtual slides for your research

tasks. ZEN image analysis tools process your data accurately.

Virtual slides are organized in a web-based database where you can view your

data at any time, regardless of where you are or what operating system you are

using. Share your images online with colleagues and organize entire projects,

even when you are on the go.

Your Fast and Flexible Slide Scanner for Fluorescence and Brightfield

› In Brief

› The Advantages

› The Applications

› The System

› Technology and Details

› Service

3

Simpler. More Intelligent. More Integrated.

Fluorescence Images:

High Speed. Top Quality.

Now you can digitize up to five fluorescence

channels using three synchronized high-speed filter

wheels for excitation, beam splitting and emission.

Using standard filter cubes it is possible to capture

up to 9 fluorescence channels. Even so, speed alone

is not enough. With its sensitive cameras, highly

corrected optics and perfected light sources,

Axio Scan.Z1 achieves the best possible image

quality. The fast LED light source Colibri 7 treats

your samples very gently. You can switch excitation

wavelengths in milliseconds and when using triband

and quadband filter sets, no mechanical compo-

nents will move in the optical beam path.

The Modular Tray Concept:

Allow Your System to Grow

Decide how many slides, what detection modes

and what camera you want to use at the outset,

then retrofit your Axio Scan.Z1 as required:

as your tasks grow, it grows alongside them.

The tray design affords you maximum freedom

with very broad tolerances for the slides, giving

you the capacity for digitizing specimen slides

of 26 mm × 77 mm, 52 mm × 77 mm and

106 mm × 77 mm.

Reproducible Results Through Automatic

Adjustment Routines

Calibrate your Axio Scan.Z1 automatically from

geometry to color rendition. Your virtual slides will

be reproduced precisely at any time: comparable

between systems and over time. Your Axio Scan.Z1

is designed to generate a high volume of repro-

ducible data - unattended and over long periods

of time. You can now add ZEISS Predictive Service:

expert service technicians remotely monitor your

system performance. They diagnose component

status and preventive maintenance can be

scheduled to your convenience. You profit from

maximum system uptime.

› In Brief

› The Advantages


› The System


› Service

4

Your Insight into the Technology Behind It

Gentle and Fast LED Illumination Gives You Reproducible Data

Speed, gentle treatment and the optimal wavelength are what counts when it comes to multispectral

fluorescence imaging. That's why Axio Scan.Z1 employs fast and reproducible LED illumination. Automatic

calibration guarantees reproducible output power levels for each wavelength. You always get consistent

quantitative data. Using triband and quadband filter sets, Axio Scan.Z1 generates multichannel images

within milliseconds for highest acquisition speed. You can acquire up to 9 spectrally separated fluorescence

channels with single band filtersets. Highly sensitive cameras give you perfect image quality. You profit from

shortest possible exposure times, maximum specimen protection and unparalleled information density.

You get highest imaging speed without compromising data quality.

Freely Definable Profiles:

Flexibility Meets Ease of Operation

Axio Scan.Z1 affords you maximum freedom in

the choice of components as well as in controlling

your imaging. You will always have access to all

the settings yet it's very easy to operate, thanks

to automated and monitored profiles for your

experiments.

› In Brief

› The Advantages


› The System


› Service

5

ZEISS Predictive Service

Maximizes System Uptime

Once connected to your network and activated,

this advanced technology will automatically track

the health status of your instrument and collect

system log files in the background to improve

remote diagnosis.

Relevant technical data such as operating hours,

cycle counts or voltages are periodically moni-

tored via a secure connection to our data center.

The ZEISS Predictive Service application evaluates

the performance of your microscope as system

data can be received and analyzed.

Our support engineers will diagnose any issues by

analyzing data on the Enterprise Server – remotely

and without interruption to your operation.

Expand Your Possibilities

• Maintain highest system availability

Increase your uptime through close monitoring

of the system’s condition as remote support

can often provide immediate solutions

• Data security

Ensure highest data security standards using well

established technologies like PTC Thingworx and

Microsoft Azure Cloud. No personal or image

data is uploaded, only machine data

• Fast and competent support

Use secure remote desktop sharing to easily

get an expert connected

• Optimum instrument performance

As the status of your system is monitored,

necessary actions can be planned before they

become urgent

Your NetworkZEISS

Enterprise Server

HTTPS

HTTPS

› In Brief

› The Advantages


› The System


› Service

6

ZEN Software: Versatile and Easy

Advanced imaging software brings real benefits to

biomedical research, coping with your wideranging

and complex tasks while remaining easy to operate.

ZEN imaging software from ZEISS is founded upon

an intuitive user concept. You define the functions

for users and user groups according to knowledge

and responsibilities. ZEN then responds by proposing

settings and following up with action where appro-

priate. Smart Setup, for example, provides you

with an intuitive interface and workflow even for

complex fluorescence samples. Just choose the

dyes and ZEN will propose all the other settings.

That way you can work quickly and safely –

especially when several peers are accessing one

device.

Seamless Imaging: Capture and Process

ZEN lets you capture virtual slides as well as analyze them and then continue processing the image data –

all on the one and same platform. A wizard sorts the image analysis functions and you can create an algorithm

with just a few mouse clicks. ZEN makes your images sharper and smoother, reinforcing contours and contrasts,

and you can also control brightness and color. Meanwhile deconvolution produces crystal clear images that

correspond to an optical section, free of out-of-focus light.


› In Brief

› The Advantages


› The System


› Service

7

Open Platform:

Securely Storing Your Images

You will usually capture a large number of slides

with Axio Scan.Z1. These images are valuable,

of course, and you will naturally want to be able

to evaluate them in future analyses. ZEN works

with an open and documented interface that lets

you access your data with your own programs.

Unlike a closed platform, this means you can

export the images and continue using the data

in any way you choose.


Images with Metadata:

Ready at the Click of a Button

In addition to image data, ZEN stores metadata,

putting away a complete record of all the operations

in a log file so you can retrieve the data at the click

of a button. This facilitates documentation and re-

producibility.

› In Brief

› The Advantages


› The System


› Service

8

ZEN lite: Free Basic Software from ZEISS

Axio Scan.Z1 comes complete with ZEN lite, the

standard software package for editing and viewing

your images. You can use the overview screen to

navigate to your regions of interest.

Even the labeling area of the slide is always visible.

Make annotations at will with circles, rectangles,

lines, arrows, text, contours and profiles. Compare

up to 16 images and then link them for navigation,

thus – for example – creating a way to make a direct

comparison with serial sections. You can process

the CZI file format from ZEISS as well as images in

TIFF, JPEG, PNG and GIF format.

Choose 2D or other views, or use the gallery.

Use sharpen, blur, geometric functions and color

adjustments in single and batch mode.

With ZEN lite, you can carry out simple interactive

measurements and export your measurements

(such as lengths, areas and angles) as data tables

for your spreadsheet program. Rounding off the

ZEN lite solution are the zooming workspace,

design schemas for darkened and bright areas.


› In Brief

› The Advantages


› The System


› Service

9


ZEN browser:

It's Easy to Organize Your Data

Virtual slides provide you with a multitude of

valuable data so you will need plenty of storage

space and a good filing structure to achieve high

throughput. ZEN browser organizes your data

online and cross-platform via an intuitive web

interface. That keeps your images filed together

with metadata and supporting documents.

The user management function restricts access

to authorized individuals only. Simply go to

www.zeiss.com/zen-browser to access our demo

server with impressive Axio Scan.Z1 imaging data.

Use the free ZEN browser app for iPads to access

your image database via a mobile front end. Down-

load the app to your iPad via www.appstore.com/

zenbrowser. Now you can access your data wherever

work takes you: just imagine presenting your latest

virtual specimen to an astonished colleague at the

next conference! You can insert annotations and

view images in transmitted light and multichannel

fluorescence images with a Z stack.

The CZI format from ZEISS provides a wealth of

benefits, and is supported by a growing number

of other manufacturers. For an updated list, please

visit www.zeiss.com/czi.

› In Brief

› The Advantages


› The System


› Service

10

Tailored Precisely to Your Applications

Typical Applications / Typical Samples Task ZEISS Axio Scan.Z1 Offers

The pathogenesis of Alzheimer‘s and other age-related diseases

Developing analytical models for amyloid deposition (plaques) High-resolution virtual slides in brightfield with image analysis

Cancer research Researching the basics of cancer Excellent image quality in fluorescence combined with high throughput thanks to fast filter wheels and sensitive cameras

ADME / Toxicology Automated image analysis workflow and peer reviews with colleagues at other locations

Findings are reproducible thanks to automated calibration, image analysis, and remote viewing

Fluorescence in-situ hybridization (FISH) Determining the number of single sequence copies in the genome Multichannel fluorescence, extended depth of field

Target identification and characterization Identifying and characterizing targets for pharmaceutical active substance searches

Sensitive fluorescence imaging combined with gentle treatment of specimens, image analysis functions

Immunological response to allografts and xenografts Identifying specific cell phenotypes and developing an understanding of cellular interactions in tissues

High dynamic range and zero artifact imaging

Research in the area of neurotraumas Quantifying brain injury measurements, including functional pathways of regeneration and microglia

Z stack imaging and robust digitization of the samples with high throughput

Tissue microarrays (TMA) Resource-friendly use of reagents and tissues with increased throughput Reliable sample detection and robust scanning process

Contract research in the biomedical field Use of slides that are hard to standardize and various applications Flexible and configurable imaging options and tray concept

Organization of expert networks Organizing the efficient exchange of information from experts around the world (e.g., cancer centers, tumor databases)

Database with integrated platform-independent access to images and documents

Inter-study group information management Sustained organization of the data pool in local study groups and evaluation of research findings

Multi-user access to database with specific access rights

Exchange of information during spur of the moment discussions / meetings

Discussing findings with peers spontaneously, irrespective of location Excellent image quality and remote data access, including by iPad

Publishing projects online Making own data and images accessible to other people Project-based web-centric database system with integrated web-viewing

› In Brief

› The Advantages


› The System


› Service

ZEISS Axio Scan.Z1 at Work

11

Kidney section, 4 μm, PAS (Periodic acid-Schiff reaction) stained glomerulus. Courtesy of K. Isse, Department of Pathology, University of Pittsburgh, USA; T. Starzl, Transplantation Institute, USA

Colon tissue, 4 μm, qDOT labeled: DAPI, CD56, CD3, CD68 and CD20. Courtesy of K. Isse, Department of Pathology, University of Pittsburgh, USA; T. Starzl, Transplantation Institute, USA


Kidney section, 4 μm, PAS (Periodic acid-Schiff reaction) stained glomerulus. Courtesy of K. Isse, Department of Pathology, University of Pittsburgh, USA; T. Starzl, Transplantation Institute, USA

Mouse brain, 5 μm, cryo section, qDOT labeled: DAPI, CD31 (endothel), GFAP (astrocytes). Courtesy of K. Isse, Department of Pathology, University of Pittsburgh, USA; T. Starzl, Transplantation Institute, USA

› In Brief

› The Advantages


› The System


› Service

12


Rat knee, 5 µm, Sirius red. Linear crossed polarization is a good method to analyze structures which cannot be differentiated by standard bright field. Samples can be digitized faster than with fluorescent labels. This is especially useful for fibrosis analysis, validation of implantation progress and analysis of bone structures.


Cryohistology of Mineralized Tissue. Multiple rounds of staining and imaging allowed the analysis of unique biological relationships between different labeled structures in mouse femur serial sections. Fluorescent reference markers at the periphery where used to align individual images of the same sections. (A) Mineralized tissue containing mineral labels (green, red) and stained with calcein blue (white), (B) tartrate resistant acid phosphatase (TRAP) stain for osteoclasts (yellow), (C) alkaline phosphatase (red) and DAPI nuclei (blue), and (D) hematoxylin stain.

2000 µm

A CB D› In Brief

› The Advantages


› The System


› Service

5

1 2 3 4

13

ZEISS Axio Scan.Z1: Your Flexible Choice of Components

1 Microscope

• Axio Scan.Z1

• Magazines for 12 or 100 slides

• Trays for four 26 mm × 77 mm slides, two

52 mm × 77 mm slides or 48 mm × 26 mm and

106 mm × 77 mm slides

2 Objectives

• N-Achroplan (2.5×, 10×, 20×, 40×)

• Fluar (2.5×, 5×)

• Plan-Apochromat (10×, 20×, 40×)

• Other objectives on request

3 Illumination

• Transmitted light: LED (wavelength

400 to 700 nm, maximum at 460 nm)

• Fluorescence: LED: 385 nm, 423 nm, 511 nm,

555 nm, 590 nm, 631 nm, 735 nm

or HXP 120 V

• Filter wheels:

• 10-position ACR for filter cubes or

• 6-position high-speed excitation

• 6-position high-speed beamsplitter

• 6-position high-speed emission

4 Cameras

• Hitachi HV F202

• Axiocam 506 mono

• Hamamatsu ORCA-Flash 4.0

5 Software

• ZEN slidescan

• ZEN lite

• ZEN browser

› In Brief

› The Advantages


› The System


› Service

Camera Set 3CCDHitachi HV-F202SCL for Axio Scan.Z1426513-9000-000plusZEN Software Driver Hitachi (Dongle)410136-1057-120orZEN Software Driver Hitachi (Software License Key)410136-0057-120

Magazine 12 slides for Axio Scan.Z1432337-9003-000orMagazine 100 slidesfor Axio Scan.Z1432337-9013-000

Camera Adapter60N-C 1" 1.0x426114-0000-000

Support for mounting of 4 slides 26 x 76 mmor mounting of 2 slides 52 x 76 mm

Accessories:Case for transport and storage for 4 mounting frames 432337-9040-000

optional:Universal desk for microscope systems1500 x 800 mm 430025-9201-000

System Overview Axio Scan.Z1 for brightfield applications

Country-specific language package

Tube module 60N, 90°for Axio Scan.Z1 425524-9000-000

High-End Workstation ZEISS 55 A Rev. 2410203-9909-000

4x Memory 32 GB (2 x 16) DDR3-1600 MHz ECC registered RAM 410303-3202-000

Fluar 5x/0.25 420130-9900-000plus up to 4 other objectsfrom the following list:

Monitor TFT 24" HPZ24n (61 cm) (O)410350-2405-000

Local Area Network

ZEN 2.3 slidescan (Dongle)410135-1006-230

Mounting frame for 1 slide 100 x 76 mm432337-9080-000

Mounting frame insert for 1 slide 28 x 48 mm432337-9090-000

Mounting frame for 2 slides 52 x 76 mm432337-9030-000


Axio Scan.Z1 430038-9001-000

Upgrade kit Polarization430038-9010-000

Fluar 2.5x/0.12 420120-9901-000Plan-Apochromat 10x/0.45 420640-9900-000Plan-Apochromat 20x/0.8420650-9902-000Plan-Apochromat 40x/0.95 Korr420660-9970-000 N-Achroplan 2.5x/0.07 420920-9901-000N-Achroplan 10x/0.25 420940-9901-000N-Achroplan 20x/0.45420950-9901-000N-Achroplan 40x/0.65 420960-9901-000

Accessories:Case for transport and storage for 4 mounting frames 432337-9040-000

Mounting frame for 1 slide 100 x 76 mm432337-9080-000

Mounting frame support for 1 slide 28 x 48 mm432337-9090-000




optional:Universal desk for microscope systems 1500 x 800 mm430025-9201-000

Tube module 3x 60N mot. 90°for Axio Scan.Z1 425524-9010-000


Camera Adapter60N-C 1" 1.0x426114-0000-000

Camera Set Axiocam 506 m for Axio Scan.Z1426513-5020-000

Reflected-light illumination mot. FL for Axio Scan.Z1423670-9000-000

Replacement:Lightguide HXP with liquid fill, 2 m 000000-0482-760Lamp HXP 120000000-0482-730

4x Memory 32 GB (2 x 16) DDR3-1600 MHz ECC registered RAM 410303-3202-000

Fluar 5x/0.25 420130-9900-000plus up to 4 other objectivesfrom the following list:Fluar 2.5x/0.12 420120-9901-000Plan-Apochromat 10x/0.45 420640-9900-000Plan-Apochromat 20x/0.8420650-9902-000Plan-Apochromat 40x/0.95 Corr420660-9970-000

Camera Set Hitachi HV-F202SCL for Axio Scan.Z1426513-9000-000plus

orZEN Software Driver Hitachi (Dongle)410136-1057-120

ZEN Software Driver Hitachi (Software License Key)410136-0057-120

Magazine 12 slides for Axio Scan.Z1432337-9003-000orMagazine 100 slidesfor Axio Scan.Z1432337-9013-000

High-End WorkstationZEISS 55 A Rev. 2410203-9909-000

System Overview Axio Scan.Z1 for brightfield and fluorescence applications


Local Area Network

ZEN Software Driver Hamamatsu Cameras(Dongle)410136-1045-110orZEN Software Driver Hamamatsu Cameras(Software License Key) 410136-0045-110

Camera Set Hamamatsu Orca Flash 4.0 K3 for Axio Scan.Z1426513-9013-000plusCamera Adapter

60N-C 1" 1.0x426114-0000-000

Filter wheels 2x 6 Pos. Beamsplitter and Emission 424953-9012-000orReflector turret mot. 10 pos.with ACR for P&C modules for Axio Scan.Z1424953-9002-000

or:HXP 120 V illuminator423013-9010-000HXP illumination adapter433302-0000-000Optical fiber sheath423302-9000-000

Axio Scan.Z1 430038-9001-000

Upgrade kit Polarization430038-9010-000

Support for mounting of 4 slides 26 x 76 mmor mounting of 2 slides 52 x 76 mm

Trigger-Board PCI xPress Rev. 5410358-0103-000

Trigger cable for trigger board Rev. 4 and Axio Scan430038-5034-000

optional:Solid-State Light Source Colibri 7, Type RGB-UV , 423052-9710-000Solid-State Light Source Colibri 7, Type RYB-UV , 423052-9720-000Solid-State Light Source Colibri 7, Type R [G / Y] B-UV, 423052-9730-000Solid-State Light Source Colibri 7, Type R [G / Y] CBV-UV, 423052-9741-000Solid-State Light Source Colibri 7, Type FR-R [G / Y] BV-UV, 423052-9770-000

14

System Overview

› In Brief

› The Advantages


› The System


› Service

System Overview of Axio Scan.Z1 network solution

Storage Area Network Wide Area NetworkLocal Area Network

PC for system control


Server(image and project database)

Axio Scan.Z1430038-9001-000

Monitor TFT 27" HP Z27n (68 cm)410350-2700-000

ZEN (blue edition)

Further information and configuration options see ZEN (blue edition)



Remote Workstation(configuration example)

Image and Database Server ZEISS410204-0000-000 (Tower)or 410205-0000-000 (Rack)

optional:Additional 11 TB HDD (RAID 6)for Image and Database Server ZEISS410324-0015-000

ZEN 2 browser (Dongle)410135-1007-200

ZEN 2 browser (Software License Key)410135-0007-200


Image analysis workstation 1 ... n(configuration example)

- 2x Intel Xeon- 64 GB RAM- 22 TB HDD (RAID 6)- Redundant power supply - Redundant fan kit- Windows Server 2012 R2 64Bit, english- Keyboard and mouse

High-End WorkstationZEISS 55 A Rev. 2 410203-9909-000

4x Memory 32 GB (2x16) DDR3-1600 MHz ECC registered RAM 410303-3202-000


Mid-Range Workstation410202-0000-000

2x Memory 16 GB (2x8) DDR3-1600 MHz ECC410303-1602-000


High-End WorkstationZEISS 55 A Rev. 2 410203-9909-000

4x Memory 32 GB (2x16) DDR3-1600 MHz ECC registered RAM 410303-3202-000


15

System Overview

› In Brief

› The Advantages


› The System


› Service

16

Dimensions (width × depth × height)

Axio Scan.Z1 (brightfield) approx. 695 mm × 579 mm × 813 mm

Axio Scan.Z1 (brightfield and fluorescence with Colibri 7) approx. 912 mm × 579 mm × 813 mm

Mass

Axio Scan.Z1 (brightfield, 12 slides) approx. 98 kg

Axio Scan.Z1 (brightfield and fluorescence with Colibri 7 and 100 slides) approx. 112 kg

Environmental conditions for transport (in packaging)

Permissible ambient temperature –40 °C to +70 °C

Storage

Permissible ambient temperature +10 °C to +40 °C

Permissible relative humidity (without condensation) max. 75 % at 35 °C

Operation

Permissible ambient temperature +10 °C to +30 °C

Permissible relative humidity max. 75 % at 30 °C

Highest permitted altitude of use max. 2000 m

Atmospheric pressure 500 hPa to 1060 hPa

Degree of pollution 2

Operating data

Operational area closed spaces

Protection class I

Ingress protection rating IP 20

Electrical safety conforms to DIN EN 61010-1 (IEC 61010-1) in consideration of CSA and UL directives

Overvoltage category II

RFI suppression under EN 55011 class A

Noise immunity under DIN EN 61326-1

Input voltage, basic unit (Mains voltage does not need to be converted!) 100 V AC to 240 V AC

Power frequency 50 / 60 Hz

Power consumption max. 260 VA

Fuses 2× T 5.0 A / H 250 V, 5 × 20 mm

Technical Specifications

› In Brief

› The Advantages


› The System


› Service

17


Pixel resolution (example: Hitachi HV F202)

10× 0.44 µm / pixel

20× 0.22 µm / pixel

40× 0.11 µm / pixel

Reflector turret

Reflector turret with ACR for push and click filter sets

Number of channels 10

Type Optically encoded (no detents)

Switching time Approx. 400 ms (from eye to eye)

High-speed filter wheels for single filter or beamsplitter

Number of channels 6


Separate control of excitation, beamsplitter and emission filter wheel

Switching time Approx. 50 ms (from eye to eye)

Motorized condenser wheel

Number of positions 9


Contrasting techniques

Transmitted light brightfield

Transmitted light Ring Aperture Contrast (RAC)

Transmitted light linear polarization

Reflected light fluorescence

› In Brief

› The Advantages


› The System


› Service

18


Fluorescence light sources Transmitted light source

Colibri 7 VIS-LED

HXP 120 V

Thumbnail generation

Labeling area Separate camera with reflected light illumination

Specimen area (brightfield) Separate camera with transmitted light illumination

Specimen area (fluorescence) 2.5× or 5× objective with transmitted light illumination (RAC) or reflected light illumination (fluorescence)

Z stack

Imaging of Z stacks and application of the extended depth of field

Bar codes and optical character recognition List of readable 1D bar codes List of readable 2D bar codes

Code 11 (ASCII encoding) Code Interleaved 2 of 5 DataMatrix (Numeric encoding, Alpha encoding, AlphaNumericPunc encoding, AlphaNumeric encoding, ASCII encoding, IS08 encoding)

Code 39 (ASCII encoding) Path code PDF417 (Standard encoding type) AlphaNumeric encoding, ASCII encoding

Code 39 Extended (ASCII encoding) EAN-8 (Numeric encoding) QR Code (QR code Model 1, 2 encoding)

Code 93 (ASCII encoding) EAN-13 (Numeric encoding) Micro QR Code

Code128 (UCC/EAN128) (ASCII encoding) UPC-A (Numeric encoding)

Codebar (ASCII encoding) UPC-E (Numeric encoding)

Optical Character Recognition (OCR)

Compression

Lossless or compression with JPEGXR (quality can be adjusted)

Optional software components

Image analysis ZEN (blue edition) image analysis modules

Database and remote viewing ZEN browser

Image viewing ZEN lite (freeware)

› In Brief

› The Advantages


› The System


› Service

19

Magazine

Capacity 12 slides (26 mm × 77 mm) 100 slides (26 mm × 77 mm)

Tray for 4 slides (26 mm × 77 mm) for 2 slides (52 mm × 77 mm or 48 mm x 26 mm) for 1 slide (106 mm × 77 mm)

Usable slides Length Width Thickness

26 mm × 77 mm (DIN ISO 8037/1 and A-A 50831) 73.5 mm … 77.0 mm 24.0 mm … 26.0 mm 0.8 mm … 1.3 mm

52 mm × 77 mm (DIN ISO 8037/1) 73.5 mm … 77.0 mm 50.0 mm … 52.0 mm 0.8 mm … 1.3 mm

106 mm × 77 mm 73.5 mm … 77.0 mm 99.0 mm … 106.0 mm 0.8 mm … 1.3 mm

48 mm × 26 mm 26.0 mm … 28.2 mm 46.0 mm … 48.2 mm 1.0 mm … 1.5 mm

Other dimensions on request

Speed

Brightfield 15 mm × 15 mm @ 0.22 µm / pixel 4 min

Objectives

Number of usable objectives up to 5 with automatic switching

List of usable objectives (other objectives on request)

Fluar 2.5× / 0.12 M27 Plan-Apochromat 20× / 0.8 M27 N-Achroplan 20× / 0.45 M27

Fluar 5× / 0.25 M27 Plan-Apochromat 40× / 0.95 Corr M27 N-Achroplan 40× / 0.65 M27

Plan-Neofluar 20× / 0.5 M27 N-Achroplan 2.5× / 0.07 M27 N-Achroplan 20× / 0.45 Pol M27

Plan-Apochromat 10× / 0.45 M27 N-Achroplan 10× / 0.25 M27

Cameras

Number of cameras up to 2 with automatic switching

List of usable cameras

Hitachi HV F202 (brightfield)

Axiocam 506 mono (fluorescence)

Hamamatsu ORCA-Flash 4.0 (fluorescence)


› In Brief

› The Advantages


› The System


› Service

>> www.zeiss.com/microservice

Because the ZEISS microscope system is one of your most important tools, we make sure it is always ready

to perform. What’s more, we’ll see to it that you are employing all the options that get the best from your

microscope. You can choose from a range of service products, each delivered by highly qualified ZEISS

specialists who will support you long beyond the purchase of your system. Our aim is to enable you to

experience those special moments that inspire your work.

Repair. Maintain. Optimize.

Attain maximum uptime with your microscope. A ZEISS Protect Service Agreement lets you budget for

service costs, all the while reducing costly downtime and achieving the best results through the maintained

performance of your system. Choose from service agreements designed to give you a range of options and

control levels. We’ll work with you to select the service program that addresses your system needs and

usage requirements, in line with your organization’s standard practices.

Enhance Your Microscope System.

Your ZEISS microscope system is designed for a variety of updates: open interfaces allow you to maintain

a high technological level at all times. As a result you’ll work more efficiently now, while extending the

productive lifetime of your microscope as new update possibilities come on stream.

Profit from the optimized performance of your microscope system with services from ZEISS – now and for years to come.

Count on Service in the True Sense of the Word

20

› In Brief

› The Advantages


› The System


› Service

Not

for t

hera

peut

ic, t

reat

men

t or m

edic

al d

iagn

ostic

evi

denc

e. N

ot a

ll pr

oduc

ts a

re a

vaila

ble

in e

very

cou

ntry

. Con

tact

you

r loc

al Z

EISS

repr

esen

tativ

e fo

r mor

e in

form

atio

n.

EN_4

1_01

1_02

3 | C

Z 06

-201

8 | D

esig

n, s

cope

of d

eliv

ery,

and

tech

nica

l pro

gres

s su

bjec

t to

chan

ge w

ithou

t not

ice.

| ©

Car

l Zei

ss M

icro

scop

y G

mbH

Carl Zeiss Microscopy GmbH 07745 Jena, Germany [email protected] www.zeiss.com/axioscan

Video Play 10:

zeiss axio scan · calibration guarantees reproducible output power levels for each wavelength. you...

Documents