z- selective rh-catalyzed reduction of dienes...introduction amy wohlgemuth, raphael dada and rylan...
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Introduction
Amy Wohlgemuth, Raphael Dada and Rylan J. LundgrenDepartment of Chemistry, University of Alberta, Edmonton, AB, T6G 2G2
Acknowledgements
Supported by:
Z- Selective Rh-Catalyzed Reduction of Dienes
Making of the Starting Material (Diene)
Conclusion
- Wittig Reaction
- Synthesis of Wittig Reagent
References1. Org. Synth. 2012, 89, 501-509.2. J. Am. Chem. Soc, 2015,137,3482-3485.3. Angew. Chem. Int. Ed. 2014, 53, 4186-4190.4. Angew. Chem. Int. Ed. 2018, 57, 3981-3984.
Selective Z-Olefin Synthesis
- Achieved reduction of diene to obtain Z-olefin.- Reaction achieved under mild condition. - This method has been shown to tolerate other
unsaturated functionalities.
Yield = 0.1g, 80%
NMR spectra of diene
NMR spectra of Z-olefin product
HAHC,HDHB
HA
HD
HB,HC