you don't think being overweight impacts …...you don't think...
TRANSCRIPT
Body Mass Index (BMI) is an approximate measure of whether someone is underweight, healthy weight or overweight. It is calculated by (weight in kg ÷ height in m2) [1].
Although BMI does not perfectly correlate with fat mass, it provides an estimated risk of disease [1].
BMI is divided into four categories:
The World Health Organization estimates
39% of adults worldwide are
overweight and 13% are obese [2].
Over 340 million children worldwide, aged 5-19 years, are overweight or obese [2].
How does weight gain cause infertility in men?
Excess weight disrupts hormone levels resulting in
ovulation problems and conception
di�culties [9].
Excess weight increases the risk of
miscarriage, gestational diabetes
and stillbirth [9,10].
Obese women with a history of unexplained recurrent miscarriages have a 73%
increased risk of experiencing another miscarriage [10].
Excess weight in women with polycystic ovarian syndrome (the leading cause of infertility among
women of reproductive age) impairs ovulation and conception
chances [9].
Folate supplementation is
less e�ective in preventing neural
tube defects in obese women [16].
Maternal overweight and obesity increases a
prospective child’s risk of asthma. Gaining more
than 25 kg during pregnancy increases
inflammation in the child’s airways, causing asthma by 9 years of age [17, 18].
Excessive weight gain during pregnancy increases a prospective child’s risk of
obesity. This predisposes them to chronic diseases later in life [19].
Obese women have a 37% increased risk of
miscarriage [14].
Obese women with poor blood sugar control (as seen in
diabetes) have a 4-fold increased risk of miscarriage [15].
Maternal obesity increases the risk of a
child developing neural tube defects and structural heart defects 3-fold [16].
Obesity increases the risk of stillbirth and
miscarriage [10].
There is good news!
Losing weight helps to regulate the menstrual cycle, can
restore ovulation and improves sperm parameters. This directly increases a couple’s chance of conceiving and taking home a
healthy baby [13].
Weight loss of 10% body weight for women over 100 kg can restart ovulation. Even a 5 kg loss increases the chance of
giving birth to a baby by 61.9% [13].
The closer to your ideal weight when trying to conceive, the better your chances of taking home a healthy baby when all major factors impacting conception in a couple’s case are
taken into consideration.
Overweight and obese women require higher doses of hormones, have fewer oocytes retrieved and have increased cycle cancellation rates when undergoing assisted reproductive therapies. This
reduces the chance of successful conception even through ICSI or IVF [12].
Obesity increases the risk of gestational diabetes, a condition
that a�ects ~14% of pregnant women worldwide [11].
Gestational diabetes increases the risk of preterm and Caesarean
delivery, and giving birth to a large-for-gestational age baby. This increases the child’s risk of obesity, heart disease and blood
sugar problems [11].
Increased weight a�ects hormone levels which decreases the production of testosterone from Leydig cells in the testes.
The number of sperm is reduced, their ability to swim is decreased and their size and shape are abnormal. This inhibits sperm’s ability
to fertilize an egg [5].
Excess weight upregulates expression of the hormone - Ghrelin, which inhibits testicular function, also causing poor sperm health and infertility [7].
Overweight and obese men have increased heat around the testes. This induces oxidative stress and damages sperm [8].
41 million children worldwide, under the age of 5, are overweight or obese [2].
KGWEIGHT m2
HEIGHT
BMI
- Less than 18.5 kg/㎡ is underweight
- 18.5-24.9 kg/㎡ is healthy weight
- More than 25 kg/㎡ is overweight
- More than 30 kg/㎡ is obese
UN
DER
WEI
GH
T
HEALTHY
WEIGHT
OVERWEIGHT
OB
ESE
18.5 kg/m2
25 kg/m2
30 kg/m2
39%Overweight
13%Obese
5-19YEARS
Reduced numberof sperm
Abnormal sizeand shape
Decreasedability to swim
73%
14%
ICSI
IVF
100KG 5kg / 10%
61.9%
37%
4x
3x
[1] http://apps.who.int/iris/bitstream/han-
dle/10665/44583/9789241501491_eng.pdf?sequence=1
[2] http://www.who.int/mediacentre/factsheets/fs311/en/
[3] https://www.betterhealth.vic.gov.au/health/healthyliving/pregnancy-and-diet
[4] https://www.iasj.net/iasj?func=fulltext&aId=64666
[5] https://www.ncbi.nlm.nih.gov/pubmed/22693175/
[6] https://www.ncbi.nlm.nih.gov/pubmed/14511216/
[7] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464503/
[8] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4492061/
[9] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4456969/
[10] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3515955/
[11] http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD009021.pub2/full
[12]https://www.researchgate.net/publication/233740615_Impact_of_overweight_a
nd_underweight_on_assisted_reproduction_treatmen
[13] https://www.ncbi.nlm.nih.gov/pubmed/28739335?dopt=Abstract
[14] https://www.fertstert.org/article/S0015-0282(07)01525-7/fulltext
[15] https://academic.oup.com/humrep/article/19/7/1644/2356447
[16] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5096465/
[17] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5695645/
[18] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3735244/
[19] https://www.ncbi.nlm.nih.gov/pubmed/29421859
[20] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4691969/
[21] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405647/
[22] https://www.ncbi.nlm.nih.gov/pubmed/29698651
[23] https://www.ncbi.nlm.nih.gov/pubmed/20858697
[24] http://www.who.int/dietphysicalactivity/factsheet_adults/en/
References:
THINK AGAIN!A H E A LT H Y B A B Y ?
B E I N G O V E R W E I G H TI M PA C T S Y O U RC H A N C E S O F G E T T I N G P R E G N A N T A N D TA K I N G H O M E
YOU DON'T THINK
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Who do you know who has been trying to conceive or take a healthy pregnancy to term for over 2 years? Apply for a complimentary fertility assessment with our team today.
For more information visit:
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Increased weight in males disrupts hormones and
increases inflammation in the body, leading to
infertility [5].
The Thermal E�ect
The Real Impact of Excess Weight on Fertility, Miscarriage Risk and Reproductive Outcomes Revealed
Waist-to-hip ratio (WHR) can be used in conjunction with BMI to determine abdominal adiposity and the risk of type 2 diabetes, cardiovascular disease and reproductive function issues including ovarian and testicular cancers. WHR is calculated by (waist measurement in cm ÷ hip measurement in cm) [1].
To decrease disease risk and subfertility, the ideal waist circumference and waist-to-hip ratios are:
For Men
85cm (waist circumference) 0.9 (WHR)
For Women
80cm (waist circumference) 0.7 (WHR)
THE IMPACT OF OVERWEIGHT AND OBESITY ON MALE FERTILITY AND REPRODUCTIVE OUTCOMES
THE IMPACT OF OVERWEIGHT AND OBESITY ON FEMALE FERTILITY AND REPRODUCTIVE OUTCOMES
For women of a healthy weight, gaining 11.5 to 16 kg
during pregnancy is recommended [3].
For women overweight, gaining 5 to 11.5 kg during pregnancy is suggested.
However, the recommendation is to optimise weight prior to becoming pregnant to reduce
complications [3].
Overweight and obesity increase the risk of type 2 diabetes, high blood pressure,
cardiovascular disease, metabolic syndrome, pancreatitis and musculoskeletal diseases [4].
11.5 to 16 kg 5 to 11.5 kg
HEALTHY OVERWEIGHT
Overweight and obesity are a rising global problem.
Overcoming inferfility and recurrent
pregnancy loss in most instances is a task you are very unlikely to be able to accomplish on
your own.
The trouble of staying in this
place too long is that it can result
in no baby.
Self-prescription and treatment when it comes to fertility and recurrent miscarriage is a recipe for continuing to try with very low (to no) chance of
success. Finding the right team for you is of paramount importance.
VITAL CONSIDERATION WHEN WORKINGTO OPTIMISE YOUR CHANCES OFTAKING HOME A HEALTHY BABY
You will need a qualified team, with a proven track record to support you along this journey because under each area
addressed here, there are dozens (if not many more) clues leading to di�erent paths—and if you don’t know what you are doing and lack a very strong, scientific and objective compass,
you will get lost and continue going around in circles until, eventually, you run out of time all together.
Unfortunately, the number one issue that keeps couples
stuck on their journey to
parenthood, without getting there anytime
fast is that they “don’t know what they don’t know”.
Whenever someone says “I’ve tried everything and nothing has worked” it is a sure fire
clue they have exhausted the end of what they knew could
help them and they have arrived in the land of “I don’t
know what I don’t know”.
Fertility is a team sport. Male fertility has a 50% impact on the increased risk of miscarriage and adverse
pregnancy outcomes [20].
Hence why it is essential for both prospective parents to optimise their health prior to a conception attempt,
and why not doing so could mean the di�erence between having a baby or not.
Here are some suggestions you and your partner can begin implementing now.
SCIENTIFICALLY VALIDATED SELF-CARE RECOMMENDATIONS
50%
INCREASE PHYSICAL ACTIVITY
The WHO recommends a minimum of 150 minutes of moderate-intensity or 75 minutes of vigorous-intensity aerobic exercise each week for healthy weight and reduced chronic disease risk.
This translates to just 2.5 hours of moderate exercise or 1.25 hours of vigorous exercise per week [24].
For optimum fertility, aim for 300 minutes (or 5 hours) of moderate-intensity exercise per week [24].
Moderate-intensity aerobic exercise
Vigorous-intensity aerobic exercise
150-300 Minutes
75 Minutes
Regular, moderate exercise is important for optimising fertility [21].
Physically active men can improve all parameters of
their sperm health as exercise reduces in�ammation and
oxidative stress [22].
40%
In females, regular exercise positively in�uences ovarian reserve markers, balances
hormones, reduces the risk of ovulatory infertility, and when combined with dietary
modi�cations, can improve ovulation rates by almost 40% (particularly in overweight and
obese women with PCOS) [21,23].