[xls]media.nature.com · web viewsupp-table s2b supp-table s2a gene name uniprot accession fasta...

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Gene name Fasta protein description Unique peptides Spectral counts A1BG P04217 >sp|P04217|A1BG_HUMAN Alpha-1B-glycoprotein OS=Homo sapiens 12 75 A2M P01023 >sp|P01023|A2MG_HUMAN Alpha-2-macroglobulin OS=Homo sapiens 73 417 A30 A2MYE2 >tr|A2MYE2|A2MYE2_HUMAN A30 protein (Fragment) OS=Homo sapie 1 1 AAMDC Q9H7C9 >sp|Q9H7C9|AAMDC_HUMAN Mth938 domain-containing protein OS=H 1 1 AARS P49588 >sp|P49588|SYAC_HUMAN Alanine--tRNA ligase, cytoplasmic OS=H 8 10 ABCA8 O94911 >sp|O94911|ABCA8_HUMAN ATP-binding cassette sub-family A mem 2 2 ABCB9 Q9NP78 >sp|Q9NP78|ABCB9_HUMAN ATP-binding cassette sub-family B mem 1 1 ABHD14B Q96IU4 >sp|Q96IU4|ABHEB_HUMAN Alpha/beta hydrolase domain-containin 7 23 ABHD14B Q96IU4-2 >sp|Q96IU4-2|ABHEB_HUMAN Isoform 2 of Alpha/beta hydrolase d 1 1 ABHD5 Q8WTS1 >sp|Q8WTS1|ABHD5_HUMAN 1-acylglycerol-3-phosphate O-acyltran 6 20 ABI3BP Q7Z7G0 >sp|Q7Z7G0|TARSH_HUMAN Target of Nesh-SH3 OS=Homo sapiens GN 2 2 ABO Q70V32 >tr|Q70V32|Q70V32_HUMAN ABO glycosyltransferase (Fragment) O 1 1 ACAA1 P09110 >sp|P09110|THIK_HUMAN 3-ketoacyl-CoA thiolase, peroxisomal O 3 5 ACAA2 P42765 >sp|P42765|THIM_HUMAN 3-ketoacyl-CoA thiolase, mitochondrial 26 97 ACACA Q13085 >sp|Q13085|ACACA_HUMAN Acetyl-CoA carboxylase 1 OS=Homo sapi 4 9 ACACB O00763 >sp|O00763|ACACB_HUMAN Acetyl-CoA carboxylase 2 OS=Homo sapi 26 38 ACAD11 Q709F0 >sp|Q709F0|ACD11_HUMAN Acyl-CoA dehydrogenase family member 1 1 ACAD9 Q9H845 >sp|Q9H845|ACAD9_HUMAN Acyl-CoA dehydrogenase family member 2 4 ACADM P11310 >sp|P11310|ACADM_HUMAN Medium-chain specific acyl-CoA dehydr 9 20 ACADS P16219 >sp|P16219|ACADS_HUMAN Short-chain specific acyl-CoA dehydro 11 31 ACADSB P45954 >sp|P45954|ACDSB_HUMAN Short/branched chain specific acyl-Co 1 1 ACADVL P49748 >sp|P49748|ACADV_HUMAN Very long-chain specific acyl-CoA deh 25 100 ACAT1 P24752 >sp|P24752|THIL_HUMAN Acetyl-CoA acetyltransferase, mitochon 15 49 ACAT2 Q9BWD1 >sp|Q9BWD1|THIC_HUMAN Acetyl-CoA acetyltransferase, cytosoli 2 4 ACBD3 Q9H3P7 >sp|Q9H3P7|GCP60_HUMAN Golgi resident protein GCP60 OS=Homo 1 1 ACBD5 Q5T8D3 >sp|Q5T8D3|ACBD5_HUMAN Acyl-CoA-binding domain-containing pr 1 2 ACE P12821 >sp|P12821|ACE_HUMAN Angiotensin-converting enzyme OS=Homo s 1 1 ACLY P53396 >sp|P53396|ACLY_HUMAN ATP-citrate synthase OS=Homo sapiens G 10 16 ACO1 P21399 >sp|P21399|ACOC_HUMAN Cytoplasmic aconitate hydratase OS=Hom 35 113 ACO2 Q99798 >sp|Q99798|ACON_HUMAN Aconitate hydratase, mitochondrial OS= 23 90 ACOT1 Q86TX2 >sp|Q86TX2|ACOT1_HUMAN Acyl-coenzyme A thioesterase 1 OS=Hom 12 51 ACOT13 Q9NPJ3 >sp|Q9NPJ3|ACO13_HUMAN Acyl-coenzyme A thioesterase 13 OS=Ho 2 3 ACOX1 Q15067 >sp|Q15067|ACOX1_HUMAN Peroxisomal acyl-coenzyme A oxidase 1 1 1 ACP1 P24666 >sp|P24666|PPAC_HUMAN Low molecular weight phosphotyrosine p 2 2 ACSF2 Q96CM8 >sp|Q96CM8|ACSF2_HUMAN Acyl-CoA synthetase family member 2, 4 4 ACSL1 P33121 >sp|P33121|ACSL1_HUMAN Long-chain-fatty-acid--CoA ligase 1 O 39 284 ACSL3 O95573 >sp|O95573|ACSL3_HUMAN Long-chain-fatty-acid--CoA ligase 3 O 2 3 ACSL4 O60488 >sp|O60488|ACSL4_HUMAN Long-chain-fatty-acid--CoA ligase 4 O 1 1 ACSL6 Q9UKU0 >sp|Q9UKU0|ACSL6_HUMAN Long-chain-fatty-acid--CoA ligase 6 O 1 1 ACSS2 Q9NR19 >sp|Q9NR19|ACSA_HUMAN Acetyl-coenzyme A synthetase, cytoplas 2 2 ACSS3 Q9H6R3 >sp|Q9H6R3|ACSS3_HUMAN Acyl-CoA synthetase short-chain famil 1 1 ACT Q562L6 >tr|Q562L6|Q562L6_HUMAN Actin-like protein (Fragment) OS=Hom 2 8 ACT Q562M3 >tr|Q562M3|Q562M3_HUMAN Actin-like protein (Fragment) OS=Hom 1 3 ACT Q562M5 >tr|Q562M5|Q562M5_HUMAN Actin-like protein (Fragment) OS=Hom 1 1 ACT Q562V5 >tr|Q562V5|Q562V5_HUMAN Actin-like protein (Fragment) OS=Hom 1 8 ACT Q562W2 >tr|Q562W2|Q562W2_HUMAN Actin-like protein (Fragment) OS=Hom 1 4 ACTA2 P62736 >sp|P62736|ACTA_HUMAN Actin, aortic smooth muscle OS=Homo sa 33 543 ACTB P60709 >sp|P60709|ACTB_HUMAN Actin, cytoplasmic 1 OS=Homo sapiens G 17 445 ACTBL2 Q562R1 >sp|Q562R1|ACTBL_HUMAN Beta-actin-like protein 2 OS=Homo sap 4 9 ACTN1 P12814 >sp|P12814|ACTN1_HUMAN Alpha-actinin-1 OS=Homo sapiens GN=AC 40 184 ACTN4 O43707 >sp|O43707|ACTN4_HUMAN Alpha-actinin-4 OS=Homo sapiens GN=AC 36 141 ACTR10 G3V5Y4 >tr|G3V5Y4|G3V5Y4_HUMAN Actin-related protein 10 OS=Homo sap 1 1 ACTR1A P61163 >sp|P61163|ACTZ_HUMAN Alpha-centractin OS=Homo sapiens GN=AC 4 12 ACTR1B P42025 >sp|P42025|ACTY_HUMAN Beta-centractin OS=Homo sapiens GN=ACT 5 9 ACTR2 P61160 >sp|P61160|ARP2_HUMAN Actin-related protein 2 OS=Homo sapien 6 14 ACTR3 P61158 >sp|P61158|ARP3_HUMAN Actin-related protein 3 OS=Homo sapien 9 35 ACY1 Q03154 >sp|Q03154|ACY1_HUMAN Aminoacylase-1 OS=Homo sapiens GN=ACY1 6 9 ACYP2 P14621 >sp|P14621|ACYP2_HUMAN Acylphosphatase-2 OS=Homo sapiens GN= 1 1 ADA P00813 >sp|P00813|ADA_HUMAN Adenosine deaminase OS=Homo sapiens GN= 1 1 ADAM10 O14672 >sp|O14672|ADA10_HUMAN Disintegrin and metalloproteinase dom 1 1 ADAMTSL5 X6R4H8 >tr|X6R4H8|X6R4H8_HUMAN ADAMTS-like protein 5 OS=Homo sapien 1 1 ADCK3 Q8NI60 >sp|Q8NI60|ADCK3_HUMAN Chaperone activity of bc1 complex-lik 1 1 ADD1 P35611 >sp|P35611|ADDA_HUMAN Alpha-adducin OS=Homo sapiens GN=ADD1 15 21 ADD3 Q9UEY8 >sp|Q9UEY8|ADDG_HUMAN Gamma-adducin OS=Homo sapiens GN=ADD3 3 10 ADH1A P07327 >sp|P07327|ADH1A_HUMAN Alcohol dehydrogenase 1A OS=Homo sapi 17 239 ADH1B P00325 >sp|P00325|ADH1B_HUMAN Alcohol dehydrogenase 1B OS=Homo sapi 15 227 ADH1C P00326 >sp|P00326|ADH1G_HUMAN Alcohol dehydrogenase 1C OS=Homo sapi 1 1 ADH5 P11766 >sp|P11766|ADHX_HUMAN Alcohol dehydrogenase class-3 OS=Homo 16 95 Supplementary Table S2A. Proteins identified in VAT samples at 1% FDR. UniProt accession codes, Fasta protein description and the corresponding gene names (N/A means "Not Assigned") are displayed. Unique peptides and spectral counts are also reported. The FDR for peptide identification was set at 1%. UniProt accession

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Page 1: [XLS]media.nature.com · Web viewSupp-Table S2B Supp-Table S2A Gene name UniProt accession Fasta protein description Unique peptides Spectral counts A1BG P04217 >sp|P04217|A1BG_HUMAN

Gene name Fasta protein description Unique peptides Spectral counts

A1BG P04217 >sp|P04217|A1BG_HUMAN Alpha-1B-glycoprotein OS=Homo sap 12 75A2M P01023 >sp|P01023|A2MG_HUMAN Alpha-2-macroglobulin OS=Homo sap 73 417A30 A2MYE2 >tr|A2MYE2|A2MYE2_HUMAN A30 protein (Fragment) OS=Homo s 1 1

AAMDC Q9H7C9 >sp|Q9H7C9|AAMDC_HUMAN Mth938 domain-containing protein 1 1AARS P49588 >sp|P49588|SYAC_HUMAN Alanine--tRNA ligase, cytoplasmic O 8 10

ABCA8 O94911 >sp|O94911|ABCA8_HUMAN ATP-binding cassette sub-family A 2 2ABCB9 Q9NP78 >sp|Q9NP78|ABCB9_HUMAN ATP-binding cassette sub-family B 1 1

ABHD14B Q96IU4 >sp|Q96IU4|ABHEB_HUMAN Alpha/beta hydrolase domain-contai 7 23ABHD14B Q96IU4-2 >sp|Q96IU4-2|ABHEB_HUMAN Isoform 2 of Alpha/beta hydrolase 1 1

ABHD5 Q8WTS1 >sp|Q8WTS1|ABHD5_HUMAN 1-acylglycerol-3-phosphate O-acyl 6 20ABI3BP Q7Z7G0 >sp|Q7Z7G0|TARSH_HUMAN Target of Nesh-SH3 OS=Homo sapi 2 2

ABO Q70V32 >tr|Q70V32|Q70V32_HUMAN ABO glycosyltransferase (Fragment 1 1ACAA1 P09110 >sp|P09110|THIK_HUMAN 3-ketoacyl-CoA thiolase, peroxisoma 3 5ACAA2 P42765 >sp|P42765|THIM_HUMAN 3-ketoacyl-CoA thiolase, mitochondri 26 97ACACA Q13085 >sp|Q13085|ACACA_HUMAN Acetyl-CoA carboxylase 1 OS=Homo 4 9ACACB O00763 >sp|O00763|ACACB_HUMAN Acetyl-CoA carboxylase 2 OS=Homo 26 38ACAD11 Q709F0 >sp|Q709F0|ACD11_HUMAN Acyl-CoA dehydrogenase family me 1 1ACAD9 Q9H845 >sp|Q9H845|ACAD9_HUMAN Acyl-CoA dehydrogenase family mem 2 4ACADM P11310 >sp|P11310|ACADM_HUMAN Medium-chain specific acyl-CoA deh 9 20ACADS P16219 >sp|P16219|ACADS_HUMAN Short-chain specific acyl-CoA dehyd 11 31

ACADSB P45954 >sp|P45954|ACDSB_HUMAN Short/branched chain specific acyl- 1 1ACADVL P49748 >sp|P49748|ACADV_HUMAN Very long-chain specific acyl-CoA d 25 100ACAT1 P24752 >sp|P24752|THIL_HUMAN Acetyl-CoA acetyltransferase, mitoch 15 49ACAT2 Q9BWD1 >sp|Q9BWD1|THIC_HUMAN Acetyl-CoA acetyltransferase, cytos 2 4ACBD3 Q9H3P7 >sp|Q9H3P7|GCP60_HUMAN Golgi resident protein GCP60 OS= 1 1ACBD5 Q5T8D3 >sp|Q5T8D3|ACBD5_HUMAN Acyl-CoA-binding domain-containing 1 2

ACE P12821 >sp|P12821|ACE_HUMAN Angiotensin-converting enzyme OS=Ho 1 1ACLY P53396 >sp|P53396|ACLY_HUMAN ATP-citrate synthase OS=Homo sapi 10 16ACO1 P21399 >sp|P21399|ACOC_HUMAN Cytoplasmic aconitate hydratase OS 35 113ACO2 Q99798 >sp|Q99798|ACON_HUMAN Aconitate hydratase, mitochondrial 23 90

ACOT1 Q86TX2 >sp|Q86TX2|ACOT1_HUMAN Acyl-coenzyme A thioesterase 1 O 12 51ACOT13 Q9NPJ3 >sp|Q9NPJ3|ACO13_HUMAN Acyl-coenzyme A thioesterase 13 2 3ACOX1 Q15067 >sp|Q15067|ACOX1_HUMAN Peroxisomal acyl-coenzyme A oxid 1 1ACP1 P24666 >sp|P24666|PPAC_HUMAN Low molecular weight phosphotyrosin 2 2

ACSF2 Q96CM8 >sp|Q96CM8|ACSF2_HUMAN Acyl-CoA synthetase family member 4 4ACSL1 P33121 >sp|P33121|ACSL1_HUMAN Long-chain-fatty-acid--CoA ligase 39 284ACSL3 O95573 >sp|O95573|ACSL3_HUMAN Long-chain-fatty-acid--CoA ligase 2 3ACSL4 O60488 >sp|O60488|ACSL4_HUMAN Long-chain-fatty-acid--CoA ligase 1 1ACSL6 Q9UKU0 >sp|Q9UKU0|ACSL6_HUMAN Long-chain-fatty-acid--CoA ligase 1 1ACSS2 Q9NR19 >sp|Q9NR19|ACSA_HUMAN Acetyl-coenzyme A synthetase, cyto 2 2ACSS3 Q9H6R3 >sp|Q9H6R3|ACSS3_HUMAN Acyl-CoA synthetase short-chain fam 1 1

ACT Q562L6 >tr|Q562L6|Q562L6_HUMAN Actin-like protein (Fragment) OS=H 2 8ACT Q562M3 >tr|Q562M3|Q562M3_HUMAN Actin-like protein (Fragment) OS= 1 3ACT Q562M5 >tr|Q562M5|Q562M5_HUMAN Actin-like protein (Fragment) OS= 1 1ACT Q562V5 >tr|Q562V5|Q562V5_HUMAN Actin-like protein (Fragment) OS=H 1 8ACT Q562W2 >tr|Q562W2|Q562W2_HUMAN Actin-like protein (Fragment) OS= 1 4

ACTA2 P62736 >sp|P62736|ACTA_HUMAN Actin, aortic smooth muscle OS=Hom 33 543ACTB P60709 >sp|P60709|ACTB_HUMAN Actin, cytoplasmic 1 OS=Homo sapie 17 445

ACTBL2 Q562R1 >sp|Q562R1|ACTBL_HUMAN Beta-actin-like protein 2 OS=Homo 4 9ACTN1 P12814 >sp|P12814|ACTN1_HUMAN Alpha-actinin-1 OS=Homo sapiens 40 184ACTN4 O43707 >sp|O43707|ACTN4_HUMAN Alpha-actinin-4 OS=Homo sapiens 36 141ACTR10 G3V5Y4 >tr|G3V5Y4|G3V5Y4_HUMAN Actin-related protein 10 OS=Homo 1 1ACTR1A P61163 >sp|P61163|ACTZ_HUMAN Alpha-centractin OS=Homo sapiens 4 12ACTR1B P42025 >sp|P42025|ACTY_HUMAN Beta-centractin OS=Homo sapiens G 5 9ACTR2 P61160 >sp|P61160|ARP2_HUMAN Actin-related protein 2 OS=Homo sap 6 14ACTR3 P61158 >sp|P61158|ARP3_HUMAN Actin-related protein 3 OS=Homo sap 9 35

Supplementary Table S2A. Proteins identified in VAT samples at 1% FDR. UniProt accession codes, Fasta protein description and the corresponding gene names (N/A means "Not Assigned") are displayed. Unique peptides and spectral counts are also reported. The FDR for peptide identification was set at 1%.

UniProt accession

Page 2: [XLS]media.nature.com · Web viewSupp-Table S2B Supp-Table S2A Gene name UniProt accession Fasta protein description Unique peptides Spectral counts A1BG P04217 >sp|P04217|A1BG_HUMAN

ACY1 Q03154 >sp|Q03154|ACY1_HUMAN Aminoacylase-1 OS=Homo sapiens G 6 9ACYP2 P14621 >sp|P14621|ACYP2_HUMAN Acylphosphatase-2 OS=Homo sapie 1 1

ADA P00813 >sp|P00813|ADA_HUMAN Adenosine deaminase OS=Homo sapie 1 1ADAM10 O14672 >sp|O14672|ADA10_HUMAN Disintegrin and metalloproteinase do 1 1

ADAMTSL5 X6R4H8 >tr|X6R4H8|X6R4H8_HUMAN ADAMTS-like protein 5 OS=Homo 1 1ADCK3 Q8NI60 >sp|Q8NI60|ADCK3_HUMAN Chaperone activity of bc1 complex-li 1 1ADD1 P35611 >sp|P35611|ADDA_HUMAN Alpha-adducin OS=Homo sapiens GN 15 21ADD3 Q9UEY8 >sp|Q9UEY8|ADDG_HUMAN Gamma-adducin OS=Homo sapiens 3 10

ADH1A P07327 >sp|P07327|ADH1A_HUMAN Alcohol dehydrogenase 1A OS=Hom 17 239ADH1B P00325 >sp|P00325|ADH1B_HUMAN Alcohol dehydrogenase 1B OS=Hom 15 227ADH1C P00326 >sp|P00326|ADH1G_HUMAN Alcohol dehydrogenase 1C OS=Hom 1 1ADH5 P11766 >sp|P11766|ADHX_HUMAN Alcohol dehydrogenase class-3 OS=H 16 95

ADHFE1 Q8IWW8 >sp|Q8IWW8|HOT_HUMAN Hydroxyacid-oxoacid transhydrogenase 1 2ADIPOQ Q15848 >sp|Q15848|ADIPO_HUMAN Adiponectin OS=Homo sapiens GN= 2 2ADIRF Q15847 >sp|Q15847|ADIRF_HUMAN Adipogenesis regulatory factor OS= 7 74ADIRF Q5TBU2 >tr|Q5TBU2|Q5TBU2_HUMAN Adipogenesis regulatory factor (Fr 1 1ADK P55263 >sp|P55263|ADK_HUMAN Adenosine kinase OS=Homo sapiens 4 5

ADRM1 Q16186 >sp|Q16186|ADRM1_HUMAN Proteasomal ubiquitin receptor A 1 1AFG3L2 Q9Y4W6 >sp|Q9Y4W6|AFG32_HUMAN AFG3-like protein 2 OS=Homo sapi 1 1

AFM P43652 >sp|P43652|AFAM_HUMAN Afamin OS=Homo sapiens GN=AFM P 18 42AGFG1 P52594 >sp|P52594|AGFG1_HUMAN Arf-GAP domain and FG repeat-conta 1 1

AGPAT2 O15120 >sp|O15120|PLCB_HUMAN 1-acyl-sn-glycerol-3-phosphate acylt 1 5AGT P01019 >sp|P01019|ANGT_HUMAN Angiotensinogen OS=Homo sapiens 6 20

AHCY P23526 >sp|P23526|SAHH_HUMAN Adenosylhomocysteinase OS=Homo s 7 16AHCYL1 O43865 >sp|O43865|SAHH2_HUMAN Putative adenosylhomocysteinase 2 3AHNAK Q09666 >sp|Q09666|AHNK_HUMAN Neuroblast differentiation-associate 268 1093AHSA1 O95433 >sp|O95433|AHSA1_HUMAN Activator of 90 kDa heat shock prot 1 3AHSG P02765 >sp|P02765|FETUA_HUMAN Alpha-2-HS-glycoprotein OS=Homo 12 51AHSP Q9NZD4 >sp|Q9NZD4|AHSP_HUMAN Alpha-hemoglobin-stabilizing protei 1 1AIDA Q96BJ3 >sp|Q96BJ3|AIDA_HUMAN Axin interactor, dorsalization-associa 1 1AIFM1 O95831 >sp|O95831|AIFM1_HUMAN Apoptosis-inducing factor 1, mitocho 7 16AIFM2 Q9BRQ8 >sp|Q9BRQ8|AIFM2_HUMAN Apoptosis-inducing factor 2 OS=Ho 7 17AK1 P00568 >sp|P00568|KAD1_HUMAN Adenylate kinase isoenzyme 1 OS=Ho 8 25AK2 P54819 >sp|P54819|KAD2_HUMAN Adenylate kinase 2, mitochondrial O 5 8AK3 Q9UIJ7 >sp|Q9UIJ7|KAD3_HUMAN GTP:AMP phosphotransferase AK3, mi 5 16AK4 P27144 >sp|P27144|KAD4_HUMAN Adenylate kinase 4, mitochondrial O 3 5AK9 Q5TCS8 >sp|Q5TCS8|KAD9_HUMAN Adenylate kinase 9 OS=Homo sapien 1 3

AKAP12 Q02952 >sp|Q02952|AKA12_HUMAN A-kinase anchor protein 12 OS=Hom 50 144AKAP13 Q12802 >sp|Q12802|AKP13_HUMAN A-kinase anchor protein 13 OS=Hom 1 1AKAP2 Q9Y2D5 >sp|Q9Y2D5|AKAP2_HUMAN A-kinase anchor protein 2 OS=Homo 13 23AKAP2 Q9Y2D5-4 >sp|Q9Y2D5-4|AKAP2_HUMAN Isoform 2 of A-kinase anchor prot 6 10AKAP9 Q99996-3 >sp|Q99996-3|AKAP9_HUMAN Isoform 3 of A-kinase anchor prot 1 1

AKR1A1 P14550 >sp|P14550|AK1A1_HUMAN Alcohol dehydrogenase [NADP(+)] 8 24AKR1B1 P15121 >sp|P15121|ALDR_HUMAN Aldose reductase OS=Homo sapiens 7 10AKR1C1 Q04828 >sp|Q04828|AK1C1_HUMAN Aldo-keto reductase family 1 memb 24 136AKR1C2 P52895 >sp|P52895|AK1C2_HUMAN Aldo-keto reductase family 1 memb 4 7AKR1C3 P42330 >sp|P42330|AK1C3_HUMAN Aldo-keto reductase family 1 memb 7 31AKR7A2 O43488 >sp|O43488|ARK72_HUMAN Aflatoxin B1 aldehyde reductase m 8 21

ALAD P13716 >sp|P13716|HEM2_HUMAN Delta-aminolevulinic acid dehydrata 7 45ALB B7WNR0 >tr|B7WNR0|B7WNR0_HUMAN Serum albumin OS=Homo sapiens 1 3ALB C9JKR2 >tr|C9JKR2|C9JKR2_HUMAN Albumin, isoform CRA_k OS=Homo 1 2ALB P02768 >sp|P02768|ALBU_HUMAN Serum albumin OS=Homo sapiens GN 87 6109

ALDH16A1 Q8IZ83 >sp|Q8IZ83|A16A1_HUMAN Aldehyde dehydrogenase family 16 1 2ALDH1A1 P00352 >sp|P00352|AL1A1_HUMAN Retinal dehydrogenase 1 OS=Homo 33 204ALDH1A2 O94788 >sp|O94788|AL1A2_HUMAN Retinal dehydrogenase 2 OS=Homo 3 7ALDH1B1 P30837 >sp|P30837|AL1B1_HUMAN Aldehyde dehydrogenase X, mitocho 1 1ALDH1L1 O75891 >sp|O75891|AL1L1_HUMAN Cytosolic 10-formyltetrahydrofolate 33 118

ALDH2 P05091 >sp|P05091|ALDH2_HUMAN Aldehyde dehydrogenase, mitochond 29 253ALDH3A2 P51648 >sp|P51648|AL3A2_HUMAN Fatty aldehyde dehydrogenase OS= 9 26ALDH4A1 P30038 >sp|P30038|AL4A1_HUMAN Delta-1-pyrroline-5-carboxylate dehy 7 13ALDH6A1 Q02252 >sp|Q02252|MMSA_HUMAN Methylmalonate-semialdehyde dehydrog 15 32ALDH7A1 P49419 >sp|P49419|AL7A1_HUMAN Alpha-aminoadipic semialdehyde de 7 15ALDH9A1 P49189 >sp|P49189|AL9A1_HUMAN 4-trimethylaminobutyraldehyde deh 18 59ALDOA P04075 >sp|P04075|ALDOA_HUMAN Fructose-bisphosphate aldolase A 29 267

Page 3: [XLS]media.nature.com · Web viewSupp-Table S2B Supp-Table S2A Gene name UniProt accession Fasta protein description Unique peptides Spectral counts A1BG P04217 >sp|P04217|A1BG_HUMAN

ALDOB P05062 >sp|P05062|ALDOB_HUMAN Fructose-bisphosphate aldolase B 1 4ALDOC P09972 >sp|P09972|ALDOC_HUMAN Fructose-bisphosphate aldolase C 12 63ALOX15 P16050 >sp|P16050|LOX15_HUMAN Arachidonate 15-lipoxygenase OS=H 5 6AMBP P02760 >sp|P02760|AMBP_HUMAN Protein AMBP OS=Homo sapiens GN 10 31

ANAPC5 Q9UJX4 >sp|Q9UJX4|APC5_HUMAN Anaphase-promoting complex subuni 1 1ANK1 P16157 >sp|P16157|ANK1_HUMAN Ankyrin-1 OS=Homo sapiens GN=ANK 3 6

ANKFY1 Q9P2R3 >sp|Q9P2R3|ANFY1_HUMAN Ankyrin repeat and FYVE domain-con 1 1ANKRD20A1 Q5TYW2 >sp|Q5TYW2|A20A1_HUMAN Ankyrin repeat domain-containing 1 9

ANO6 Q4KMQ2 >sp|Q4KMQ2|ANO6_HUMAN Anoctamin-6 OS=Homo sapiens GN 1 2ANO7 Q6IWH7 >sp|Q6IWH7|ANO7_HUMAN Anoctamin-7 OS=Homo sapiens GN= 1 1

ANP32A P39687 >sp|P39687|AN32A_HUMAN Acidic leucine-rich nuclear phosphop 3 8ANP32B Q92688 >sp|Q92688|AN32B_HUMAN Acidic leucine-rich nuclear phospho 1 3ANP32E Q9BTT0 >sp|Q9BTT0|AN32E_HUMAN Acidic leucine-rich nuclear phospho 1 1ANPEP P15144 >sp|P15144|AMPN_HUMAN Aminopeptidase N OS=Homo sapien 4 4ANXA1 P04083 >sp|P04083|ANXA1_HUMAN Annexin A1 OS=Homo sapiens GN= 25 272ANXA11 P50995 >sp|P50995|ANX11_HUMAN Annexin A11 OS=Homo sapiens GN 7 17ANXA11 Q6ICS0 >tr|Q6ICS0|Q6ICS0_HUMAN Annexin (Fragment) OS=Homo sapi 1 2ANXA2 P07355 >sp|P07355|ANXA2_HUMAN Annexin A2 OS=Homo sapiens GN= 34 403ANXA3 P12429 >sp|P12429|ANXA3_HUMAN Annexin A3 OS=Homo sapiens GN= 7 18ANXA4 P09525 >sp|P09525|ANXA4_HUMAN Annexin A4 OS=Homo sapiens GN= 5 10ANXA5 P08758 >sp|P08758|ANXA5_HUMAN Annexin A5 OS=Homo sapiens GN= 24 149ANXA6 A6NN80 >tr|A6NN80|A6NN80_HUMAN Annexin OS=Homo sapiens GN=AN 1 1ANXA6 P08133 >sp|P08133|ANXA6_HUMAN Annexin A6 OS=Homo sapiens GN= 52 260ANXA7 P20073 >sp|P20073|ANXA7_HUMAN Annexin A7 OS=Homo sapiens GN= 5 7ANXA8 P13928 >sp|P13928|ANXA8_HUMAN Annexin A8 OS=Homo sapiens GN= 4 9AOC2 O75106 >sp|O75106|AOC2_HUMAN Retina-specific copper amine oxidas 4 24AOC3 Q16853 >sp|Q16853|AOC3_HUMAN Membrane primary amine oxidase OS 26 440AOX1 Q06278 >sp|Q06278|AOXA_HUMAN Aldehyde oxidase OS=Homo sapiens 3 9AP1B1 Q10567 >sp|Q10567|AP1B1_HUMAN AP-1 complex subunit beta-1 OS=Ho 7 10AP1G1 O43747 >sp|O43747|AP1G1_HUMAN AP-1 complex subunit gamma-1 OS 1 1AP2A1 O95782 >sp|O95782|AP2A1_HUMAN AP-2 complex subunit alpha-1 OS=H 8 13AP2A2 O94973 >sp|O94973|AP2A2_HUMAN AP-2 complex subunit alpha-2 OS=H 5 7AP2B1 P63010 >sp|P63010|AP2B1_HUMAN AP-2 complex subunit beta OS=Homo 3 5AP2M1 Q96CW1 >sp|Q96CW1|AP2M1_HUMAN AP-2 complex subunit mu OS=Homo 3 7AP2S1 P53680 >sp|P53680|AP2S1_HUMAN AP-2 complex subunit sigma OS=Ho 1 1APBA1 Q02410 >sp|Q02410|APBA1_HUMAN Amyloid beta A4 precursor protein-b 1 2

APBB1IP Q7Z5R6 >sp|Q7Z5R6|AB1IP_HUMAN Amyloid beta A4 precursor protein-bin 1 2APCS P02743 >sp|P02743|SAMP_HUMAN Serum amyloid P-component OS=Hom 7 20APEH P13798 >sp|P13798|ACPH_HUMAN Acylamino-acid-releasing enzyme O 5 13APEX1 P27695 >sp|P27695|APEX1_HUMAN DNA-(apurinic or apyrimidinic site) 6 9APMAP Q9HDC9 >sp|Q9HDC9|APMAP_HUMAN Adipocyte plasma membrane-associ 14 57APOA1 P02647 >sp|P02647|APOA1_HUMAN Apolipoprotein A-I OS=Homo sapie 48 476

APOA1BP Q8NCW5 >sp|Q8NCW5|NNRE_HUMAN NAD(P)H-hydrate epimerase OS=Ho 2 3APOA2 P02652 >sp|P02652|APOA2_HUMAN Apolipoprotein A-II OS=Homo sapie 6 31APOA4 P06727 >sp|P06727|APOA4_HUMAN Apolipoprotein A-IV OS=Homo sapi 27 100APOB P04114 >sp|P04114|APOB_HUMAN Apolipoprotein B-100 OS=Homo sapi 62 122

APOC2 P02655 >sp|P02655|APOC2_HUMAN Apolipoprotein C-II OS=Homo sapi 2 2APOC3 P02656 >sp|P02656|APOC3_HUMAN Apolipoprotein C-III OS=Homo sapi 4 25APOD P05090 >sp|P05090|APOD_HUMAN Apolipoprotein D OS=Homo sapiens 6 23APOE P02649 >sp|P02649|APOE_HUMAN Apolipoprotein E OS=Homo sapiens 9 22APOH P02749 >sp|P02749|APOH_HUMAN Beta-2-glycoprotein 1 OS=Homo sap 14 49APOL1 O14791 >sp|O14791|APOL1_HUMAN Apolipoprotein L1 OS=Homo sapien 2 2APOL2 Q9BQE5 >sp|Q9BQE5|APOL2_HUMAN Apolipoprotein L2 OS=Homo sapie 2 3APOM O95445 >sp|O95445|APOM_HUMAN Apolipoprotein M OS=Homo sapiens 3 3APOO Q9BUR5 >sp|Q9BUR5|APOO_HUMAN Apolipoprotein O OS=Homo sapien 1 2APRT P07741 >sp|P07741|APT_HUMAN Adenine phosphoribosyltransferase O 5 14AQP1 P29972 >sp|P29972|AQP1_HUMAN Aquaporin-1 OS=Homo sapiens GN=A 2 2

ARCN1 P48444 >sp|P48444|COPD_HUMAN Coatomer subunit delta OS=Homo sa 3 3ARF1 P84077 >sp|P84077|ARF1_HUMAN ADP-ribosylation factor 1 OS=Homo s 10 64ARF4 P18085 >sp|P18085|ARF4_HUMAN ADP-ribosylation factor 4 OS=Homo s 5 6ARF5 P84085 >sp|P84085|ARF5_HUMAN ADP-ribosylation factor 5 OS=Homo s 2 3ARF6 P62330 >sp|P62330|ARF6_HUMAN ADP-ribosylation factor 6 OS=Homo s 1 1

ARFGEF2 Q9Y6D5 >sp|Q9Y6D5|BIG2_HUMAN Brefeldin A-inhibited guanine nucleot 1 2ARHGAP1 Q07960 >sp|Q07960|RHG01_HUMAN Rho GTPase-activating protein 1 13 31

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ARHGAP11A Q6P4F7 >sp|Q6P4F7|RHGBA_HUMAN Rho GTPase-activating protein 11 1 3ARHGAP17 Q68EM7 >sp|Q68EM7|RHG17_HUMAN Rho GTPase-activating protein 17 1 1ARHGAP31 Q2M1Z3 >sp|Q2M1Z3|RHG31_HUMAN Rho GTPase-activating protein 31 1 2ARHGDIA P52565 >sp|P52565|GDIR1_HUMAN Rho GDP-dissociation inhibitor 1 O 8 40ARHGDIB P52566 >sp|P52566|GDIR2_HUMAN Rho GDP-dissociation inhibitor 2 O 7 16

ARHGEF11 O15085 >sp|O15085|ARHGB_HUMAN Rho guanine nucleotide exchange f 1 1ARHGEF12 Q9NZN5 >sp|Q9NZN5|ARHGC_HUMAN Rho guanine nucleotide exchange 1 2

ARID1A O14497 >sp|O14497|ARI1A_HUMAN AT-rich interactive domain-containin 1 2ARL3 P36405 >sp|P36405|ARL3_HUMAN ADP-ribosylation factor-like protein 1 3

ARL6IP5 O75915 >sp|O75915|PRAF3_HUMAN PRA1 family protein 3 OS=Homo sap 5 25ARL8B Q9NVJ2 >sp|Q9NVJ2|ARL8B_HUMAN ADP-ribosylation factor-like protei 2 7

ARPC1A Q92747 >sp|Q92747|ARC1A_HUMAN Actin-related protein 2/3 complex s 2 3ARPC1B O15143 >sp|O15143|ARC1B_HUMAN Actin-related protein 2/3 complex s 5 8ARPC2 O15144 >sp|O15144|ARPC2_HUMAN Actin-related protein 2/3 complex s 8 21ARPC3 O15145 >sp|O15145|ARPC3_HUMAN Actin-related protein 2/3 complex s 3 14ARPC4 P59998 >sp|P59998|ARPC4_HUMAN Actin-related protein 2/3 complex s 4 16ARPC5 O15511 >sp|O15511|ARPC5_HUMAN Actin-related protein 2/3 complex s 3 5

ARPC5L Q9BPX5 >sp|Q9BPX5|ARP5L_HUMAN Actin-related protein 2/3 complex su 3 4ARRB1 P49407 >sp|P49407|ARRB1_HUMAN Beta-arrestin-1 OS=Homo sapiens 3 5ARSA P15289 >sp|P15289|ARSA_HUMAN Arylsulfatase A OS=Homo sapiens G 1 1

ASAH1 D3DSQ1 >tr|D3DSQ1|D3DSQ1_HUMAN N-acylsphingosine amidohydrolase 1 1ASAH1 Q13510 >sp|Q13510|ASAH1_HUMAN Acid ceramidase OS=Homo sapiens 9 49ASIC2 Q16515-2 >sp|Q16515-2|ASIC2_HUMAN Isoform 2 of Acid-sensing ion chan 1 2ASMTL O95671 >sp|O95671|ASML_HUMAN N-acetylserotonin O-methyltransferas 1 1ASNA1 O43681 >sp|O43681|ASNA_HUMAN ATPase ASNA1 OS=Homo sapiens G 4 5ASPA P45381 >sp|P45381|ACY2_HUMAN Aspartoacylase OS=Homo sapiens G 1 2ASPH Q12797 >sp|Q12797|ASPH_HUMAN Aspartyl/asparaginyl beta-hydroxyla 29 139ASPN Q9BXN1 >sp|Q9BXN1|ASPN_HUMAN Asporin OS=Homo sapiens GN=ASPN 11 48ASS1 P00966 >sp|P00966|ASSY_HUMAN Argininosuccinate synthase OS=Homo 17 35

ATAD3A Q9NVI7 >sp|Q9NVI7|ATD3A_HUMAN ATPase family AAA domain-containi 1 1ATG3 Q9NT62 >sp|Q9NT62|ATG3_HUMAN Ubiquitin-like-conjugating enzyme 1 1ATIC P31939 >sp|P31939|PUR9_HUMAN Bifunctional purine biosynthesis pro 16 35ATL3 Q6DD88 >sp|Q6DD88|ATLA3_HUMAN Atlastin-3 OS=Homo sapiens GN=AT 11 23

ATOX1 O00244 >sp|O00244|ATOX1_HUMAN Copper transport protein ATOX1 O 1 1ATP12A P54707 >sp|P54707|AT12A_HUMAN Potassium-transporting ATPase alph 1 1ATP13A5 Q4VNC0 >sp|Q4VNC0|AT135_HUMAN Probable cation-transporting ATPa 1 1ATP1A1 P05023 >sp|P05023|AT1A1_HUMAN Sodium/potassium-transporting ATPa 7 11ATP1B1 P05026 >sp|P05026|AT1B1_HUMAN Sodium/potassium-transporting ATPa 1 1ATP2A1 O14983 >sp|O14983|AT2A1_HUMAN Sarcoplasmic/endoplasmic reticulum 5 10ATP2A2 P16615 >sp|P16615|AT2A2_HUMAN Sarcoplasmic/endoplasmic reticulum 7 8ATP2B1 P20020 >sp|P20020|AT2B1_HUMAN Plasma membrane calcium-transport 6 15ATP2B4 P23634 >sp|P23634|AT2B4_HUMAN Plasma membrane calcium-transport 8 18ATP5A1 P25705 >sp|P25705|ATPA_HUMAN ATP synthase subunit alpha, mitocho 31 168ATP5B P06576 >sp|P06576|ATPB_HUMAN ATP synthase subunit beta, mitochon 30 264

ATP5C1 P36542 >sp|P36542|ATPG_HUMAN ATP synthase subunit gamma, mitoch 7 16ATP5D P30049 >sp|P30049|ATPD_HUMAN ATP synthase subunit delta, mitocho 2 12

ATP5EP2 Q5VTU8 >sp|Q5VTU8|AT5EL_HUMAN ATP synthase subunit epsilon-like pr 1 1ATP5F1 P24539 >sp|P24539|AT5F1_HUMAN ATP synthase F(0) complex subunit B 3 6ATP5G1 P05496 >sp|P05496|AT5G1_HUMAN ATP synthase F(0) complex subunit 1 1ATP5H O75947 >sp|O75947|ATP5H_HUMAN ATP synthase subunit d, mitochondr 9 41ATP5I P56385 >sp|P56385|ATP5I_HUMAN ATP synthase subunit e, mitochondri 1 8ATP5J P18859 >sp|P18859|ATP5J_HUMAN ATP synthase-coupling factor 6, mit 3 6ATP5J2 P56134 >sp|P56134|ATPK_HUMAN ATP synthase subunit f, mitochondria 2 22ATP5L O75964 >sp|O75964|ATP5L_HUMAN ATP synthase subunit g, mitochondr 2 4ATP5O P48047 >sp|P48047|ATPO_HUMAN ATP synthase subunit O, mitochondri 9 27

ATP6V1A P38606 >sp|P38606|VATA_HUMAN V-type proton ATPase catalytic subu 3 5ATP6V1C1 P21283 >sp|P21283|VATC1_HUMAN V-type proton ATPase subunit C 1 1 1ATP6V1G1 O75348 >sp|O75348|VATG1_HUMAN V-type proton ATPase subunit G 1 1 1

ATRIP Q8WXE1 >sp|Q8WXE1|ATRIP_HUMAN ATR-interacting protein OS=Homo s 1 1AZGP1 P25311 >sp|P25311|ZA2G_HUMAN Zinc-alpha-2-glycoprotein OS=Homo 11 30

B2M P61769 >sp|P61769|B2MG_HUMAN Beta-2-microglobulin OS=Homo sapi 2 2B3GNT8 Q7Z7M8 >sp|Q7Z7M8|B3GN8_HUMAN UDP-GlcNAc:betaGal beta-1,3-N-acet 1 1BABAM1 Q9NWV8 >sp|Q9NWV8|BABA1_HUMAN BRISC and BRCA1-A complex memb 2 4

BAG2 O95816 >sp|O95816|BAG2_HUMAN BAG family molecular chaperone regu 1 1

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BAG3 O95817 >sp|O95817|BAG3_HUMAN BAG family molecular chaperone regu 3 7BAIAP3 O94812 >sp|O94812|BAIP3_HUMAN BAI1-associated protein 3 OS=Homo 1 1BANF1 O75531 >sp|O75531|BAF_HUMAN Barrier-to-autointegration factor OS= 3 3BANK1 Q8NDB2 >sp|Q8NDB2|BANK1_HUMAN B-cell scaffold protein with ankyri 1 7BASP1 P80723 >sp|P80723|BASP1_HUMAN Brain acid soluble protein 1 OS=Ho 8 19BAZ1B Q9UIG0 >sp|Q9UIG0|BAZ1B_HUMAN Tyrosine-protein kinase BAZ1B OS= 1 1BCAM P50895 >sp|P50895|BCAM_HUMAN Basal cell adhesion molecule OS=Ho 8 13

BCAP29 Q9UHQ4 >sp|Q9UHQ4|BAP29_HUMAN B-cell receptor-associated protein 2 2BCAP31 P51572 >sp|P51572|BAP31_HUMAN B-cell receptor-associated protein 7 37BCAT2 O15382 >sp|O15382|BCAT2_HUMAN Branched-chain-amino-acid aminotran 1 2BCHE P06276 >sp|P06276|CHLE_HUMAN Cholinesterase OS=Homo sapiens G 1 2

BCKDHB P21953 >sp|P21953|ODBB_HUMAN 2-oxoisovalerate dehydrogenase subun 1 1BDH2 Q9BUT1 >sp|Q9BUT1|BDH2_HUMAN 3-hydroxybutyrate dehydrogenase ty 2 2BGN P21810 >sp|P21810|PGS1_HUMAN Biglycan OS=Homo sapiens GN=BGN 13 47BIN1 O00499 >sp|O00499|BIN1_HUMAN Myc box-dependent-interacting protei 5 9

BLVRA P53004 >sp|P53004|BIEA_HUMAN Biliverdin reductase A OS=Homo sapi 7 14BLVRB P30043 >sp|P30043|BLVRB_HUMAN Flavin reductase (NADPH) OS=Homo 11 76BNC2 Q6ZN30 >sp|Q6ZN30|BNC2_HUMAN Zinc finger protein basonuclin-2 OS 1 1

BOLA2 Q9H3K6 >sp|Q9H3K6|BOLA2_HUMAN BolA-like protein 2 OS=Homo sapie 1 1BPGM P07738 >sp|P07738|PMGE_HUMAN Bisphosphoglycerate mutase OS=Ho 2 2BPHL Q86WA6 >sp|Q86WA6|BPHL_HUMAN Valacyclovir hydrolase OS=Homo sa 2 2BPNT1 O95861 >sp|O95861|BPNT1_HUMAN 3'(2'),5'-bisphosphate nucleotidase 1 2

BRE Q9NXR7 >sp|Q9NXR7|BRE_HUMAN BRCA1-A complex subunit BRE OS=H 1 1BSG P35613 >sp|P35613|BASI_HUMAN Basigin OS=Homo sapiens GN=BSG P 6 11BST1 Q10588 >sp|Q10588|BST1_HUMAN ADP-ribosyl cyclase/cyclic ADP-ribos 2 9BST2 Q10589 >sp|Q10589|BST2_HUMAN Bone marrow stromal antigen 2 OS=H 3 5BTF3 P20290 >sp|P20290|BTF3_HUMAN Transcription factor BTF3 OS=Homo s 1 1

BZRAP1 O95153 >sp|O95153|RIMB1_HUMAN Peripheral-type benzodiazepine recep 1 1BZW1 Q7L1Q6 >sp|Q7L1Q6|BZW1_HUMAN Basic leucine zipper and W2 domain-c 3 4

C11orf54 Q9H0W9 >sp|Q9H0W9|CK054_HUMAN Ester hydrolase C11orf54 OS=Homo 2 5C14orf159 Q7Z3D6 >sp|Q7Z3D6|CN159_HUMAN UPF0317 protein C14orf159, mitocho 1 1C14orf166 Q9Y224 >sp|Q9Y224|CN166_HUMAN UPF0568 protein C14orf166 OS=Hom 5 8C17orf104 A2RUB1 >sp|A2RUB1|CQ104_HUMAN Uncharacterized protein C17orf104 1 1C17orf62 Q9BQA9 >sp|Q9BQA9|CQ062_HUMAN Uncharacterized protein C17orf62 1 1C19orf10 Q969H8 >sp|Q969H8|CS010_HUMAN UPF0556 protein C19orf10 OS=Homo 2 3C19orf25 Q9UFG5 >sp|Q9UFG5|CS025_HUMAN UPF0449 protein C19orf25 OS=Homo 1 1C19orf43 Q9BQ61 >sp|Q9BQ61|CS043_HUMAN Uncharacterized protein C19orf43 O 1 2C1orf123 Q9NWV4 >sp|Q9NWV4|CA123_HUMAN UPF0587 protein C1orf123 OS=Homo 5 10C1orf168 Q5VWT5 >sp|Q5VWT5|CA168_HUMAN Uncharacterized protein C1orf168 1 1C1orf198 Q9H425 >sp|Q9H425|CA198_HUMAN Uncharacterized protein C1orf198 O 1 2

C1QA P02745 >sp|P02745|C1QA_HUMAN Complement C1q subcomponent subun 1 2C1QB P02746 >sp|P02746|C1QB_HUMAN Complement C1q subcomponent subun 3 8

C1QBP Q07021 >sp|Q07021|C1QBP_HUMAN Complement component 1 Q subcompon 1 2C1QL3 Q5VWW1 >sp|Q5VWW1|C1QL3_HUMAN Complement C1q-like protein 3 OS 1 3

C1R P00736 >sp|P00736|C1R_HUMAN Complement C1r subcomponent OS=Ho 6 7C1S P09871 >sp|P09871|C1S_HUMAN Complement C1s subcomponent OS=Ho 5 7

C20orf27 Q9GZN8 >sp|Q9GZN8|CT027_HUMAN UPF0687 protein C20orf27 OS=Homo 1 1C21orf33 P30042 >sp|P30042|ES1_HUMAN ES1 protein homolog, mitochondrial OS 8 23

C3 P01024 >sp|P01024|CO3_HUMAN Complement C3 OS=Homo sapiens GN 118 725C4A P0C0L4-2 >sp|P0C0L4-2|CO4A_HUMAN Isoform 2 of Complement C4-A OS 1 2C4B F5GXS0 >tr|F5GXS0|F5GXS0_HUMAN Complement C4-B OS=Homo sapie 55 213C4B Q6U2E0 >tr|Q6U2E0|Q6U2E0_HUMAN C4B2 (Fragment) OS=Homo sapien 1 6C4B Q6U2M2 >tr|Q6U2M2|Q6U2M2_HUMAN C4B1 (Fragment) OS=Homo sapien 2 5

C4BPA P04003 >sp|P04003|C4BPA_HUMAN C4b-binding protein alpha chain O 6 8C5 P01031 >sp|P01031|CO5_HUMAN Complement C5 OS=Homo sapiens GN 8 14C6 P13671 >sp|P13671|CO6_HUMAN Complement component C6 OS=Homo s 1 1C7 P10643 >sp|P10643|CO7_HUMAN Complement component C7 OS=Homo s 4 6

C8A P07357 >sp|P07357|CO8A_HUMAN Complement component C8 alpha cha 5 6C8B P07358 >sp|P07358|CO8B_HUMAN Complement component C8 beta chai 3 5C8G P07360 >sp|P07360|CO8G_HUMAN Complement component C8 gamma ch 1 2C9 P02748 >sp|P02748|CO9_HUMAN Complement component C9 OS=Homo s 9 14

C9orf117 Q5JU67 >sp|Q5JU67|CI117_HUMAN Uncharacterized protein C9orf117 O 1 3CA1 P00915 >sp|P00915|CAH1_HUMAN Carbonic anhydrase 1 OS=Homo sapi 12 226CA2 P00918 >sp|P00918|CAH2_HUMAN Carbonic anhydrase 2 OS=Homo sapi 12 55

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CA3 P07451 >sp|P07451|CAH3_HUMAN Carbonic anhydrase 3 OS=Homo sapi 7 16CA4 P22748 >sp|P22748|CAH4_HUMAN Carbonic anhydrase 4 OS=Homo sapi 3 5

CAB39 Q9Y376 >sp|Q9Y376|CAB39_HUMAN Calcium-binding protein 39 OS=Hom 1 2CAB39L Q9H9S4 >sp|Q9H9S4|CB39L_HUMAN Calcium-binding protein 39-like OS 1 1

CACNA1I Q9P0X4 >sp|Q9P0X4|CAC1I_HUMAN Voltage-dependent T-type calcium ch 1 4CACNA2D1 P54289 >sp|P54289|CA2D1_HUMAN Voltage-dependent calcium channel s 7 8CACNA2D1 P54289-3 >sp|P54289-3|CA2D1_HUMAN Isoform 3 of Voltage-dependent cal 1 1

CACYBP Q9HB71 >sp|Q9HB71|CYBP_HUMAN Calcyclin-binding protein OS=Homo 2 2CAD P27708 >sp|P27708|PYR1_HUMAN CAD protein OS=Homo sapiens GN=C 2 2

CADM3 Q8N126 >sp|Q8N126|CADM3_HUMAN Cell adhesion molecule 3 OS=Homo 1 1CALB1 P05937 >sp|P05937|CALB1_HUMAN Calbindin OS=Homo sapiens GN=CA 1 5CALB2 P22676 >sp|P22676|CALB2_HUMAN Calretinin OS=Homo sapiens GN=CA 12 32CALD1 Q05682 >sp|Q05682|CALD1_HUMAN Caldesmon OS=Homo sapiens GN=C 27 62CALD1 Q05682-3 >sp|Q05682-3|CALD1_HUMAN Isoform 3 of Caldesmon OS=Homo 1 1CALD1 Q05682-4 >sp|Q05682-4|CALD1_HUMAN Isoform 4 of Caldesmon OS=Homo 1 2CALM1 P62158 >sp|P62158|CALM_HUMAN Calmodulin OS=Homo sapiens GN=C 15 261

CALML3 P27482 >sp|P27482|CALL3_HUMAN Calmodulin-like protein 3 OS=Homo 2 10CALR P27797 >sp|P27797|CALR_HUMAN Calreticulin OS=Homo sapiens GN=C 16 107CALU O43852 >sp|O43852|CALU_HUMAN Calumenin OS=Homo sapiens GN=CA 6 12

CAMK1 Q14012 >sp|Q14012|KCC1A_HUMAN Calcium/calmodulin-dependent prote 1 1CAMK2A Q9UQM7 >sp|Q9UQM7|KCC2A_HUMAN Calcium/calmodulin-dependent protei 1 4CAMK2D Q13557 >sp|Q13557|KCC2D_HUMAN Calcium/calmodulin-dependent protein 4 5CAND1 Q86VP6 >sp|Q86VP6|CAND1_HUMAN Cullin-associated NEDD8-dissociate 15 25CANX P27824 >sp|P27824|CALX_HUMAN Calnexin OS=Homo sapiens GN=CAN 24 109CAP1 D3DPU2 >tr|D3DPU2|D3DPU2_HUMAN Adenylyl cyclase-associated prote 2 17CAP1 Q01518 >sp|Q01518|CAP1_HUMAN Adenylyl cyclase-associated protein 15 62CAP2 P40123 >sp|P40123|CAP2_HUMAN Adenylyl cyclase-associated protein 3 5CAPG P40121 >sp|P40121|CAPG_HUMAN Macrophage-capping protein OS=Hom 8 15CAPN1 P07384 >sp|P07384|CAN1_HUMAN Calpain-1 catalytic subunit OS=Homo 8 16CAPN2 P17655 >sp|P17655|CAN2_HUMAN Calpain-2 catalytic subunit OS=Homo 17 39

CAPNS1 P04632 >sp|P04632|CPNS1_HUMAN Calpain small subunit 1 OS=Homo s 12 36CAPZA1 P52907 >sp|P52907|CAZA1_HUMAN F-actin-capping protein subunit alp 9 33CAPZA2 P47755 >sp|P47755|CAZA2_HUMAN F-actin-capping protein subunit alp 5 20CAPZB P47756 >sp|P47756|CAPZB_HUMAN F-actin-capping protein subunit be 8 28CAPZB P47756-2 >sp|P47756-2|CAPZB_HUMAN Isoform 2 of F-actin-capping prote 1 2

CARHSP1 Q9Y2V2 >sp|Q9Y2V2|CHSP1_HUMAN Calcium-regulated heat stable prot 1 3CARKD Q8IW45 >sp|Q8IW45|NNRD_HUMAN ATP-dependent (S)-NAD(P)H-hydrate 1 1CARS P49589 >sp|P49589|SYCC_HUMAN Cysteine--tRNA ligase, cytoplasmic 1 1CAST P20810 >sp|P20810|ICAL_HUMAN Calpastatin OS=Homo sapiens GN=CA 15 35CAST P20810-5 >sp|P20810-5|ICAL_HUMAN Isoform 5 of Calpastatin OS=Homo s 1 1CAT P04040 >sp|P04040|CATA_HUMAN Catalase OS=Homo sapiens GN=CAT 29 176

CAV1 Q03135 >sp|Q03135|CAV1_HUMAN Caveolin-1 OS=Homo sapiens GN=CA 12 146CAV2 P51636 >sp|P51636|CAV2_HUMAN Caveolin-2 OS=Homo sapiens GN=CA 4 19CBR1 P16152 >sp|P16152|CBR1_HUMAN Carbonyl reductase [NADPH] 1 OS=H 14 35CBX1 P83916 >sp|P83916|CBX1_HUMAN Chromobox protein homolog 1 OS=Ho 2 2CBX3 Q13185 >sp|Q13185|CBX3_HUMAN Chromobox protein homolog 3 OS=Ho 1 1

CC2D1B Q5T0F9 >sp|Q5T0F9|C2D1B_HUMAN Coiled-coil and C2 domain-containi 1 1CCAR2 Q8N163 >sp|Q8N163|CCAR2_HUMAN Cell cycle and apoptosis regulator 1 1CCBL2 Q6YP21 >sp|Q6YP21|KAT3_HUMAN Kynurenine--oxoglutarate transamina 1 1

CCDC114 Q96M63 >sp|Q96M63|CC114_HUMAN Coiled-coil domain-containing prot 1 1CCDC168 Q8NDH2 >sp|Q8NDH2|CC168_HUMAN Coiled-coil domain-containing prot 1 1CCDC39 Q9UFE4 >sp|Q9UFE4|CCD39_HUMAN Coiled-coil domain-containing prot 1 1CCDC53 Q9Y3C0 >sp|Q9Y3C0|CCD53_HUMAN WASH complex subunit CCDC53 OS 1 1CCDC57 Q2TAC2 >sp|Q2TAC2|CCD57_HUMAN Coiled-coil domain-containing prot 1 1CCDC62 Q6P9F0 >sp|Q6P9F0|CCD62_HUMAN Coiled-coil domain-containing prot 1 1CCDC69 A6NI79 >sp|A6NI79|CCD69_HUMAN Coiled-coil domain-containing prote 1 1CCNB2 O95067 >sp|O95067|CCNB2_HUMAN G2/mitotic-specific cyclin-B2 OS=H 1 1CCNK O75909 >sp|O75909|CCNK_HUMAN Cyclin-K OS=Homo sapiens GN=CCN 1 1CCS O14618 >sp|O14618|CCS_HUMAN Copper chaperone for superoxide dis 1 1CCT2 P78371 >sp|P78371|TCPB_HUMAN T-complex protein 1 subunit beta OS 12 28CCT3 P49368 >sp|P49368|TCPG_HUMAN T-complex protein 1 subunit gamma 9 27CCT4 P50991 >sp|P50991|TCPD_HUMAN T-complex protein 1 subunit delta O 9 22CCT5 P48643 >sp|P48643|TCPE_HUMAN T-complex protein 1 subunit epsilon 8 19

CCT6A P40227 >sp|P40227|TCPZ_HUMAN T-complex protein 1 subunit zeta OS 6 13

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CCT7 Q99832 >sp|Q99832|TCPH_HUMAN T-complex protein 1 subunit eta OS= 8 16CCT8 P50990 >sp|P50990|TCPQ_HUMAN T-complex protein 1 subunit theta O 15 34CD109 Q6YHK3 >sp|Q6YHK3|CD109_HUMAN CD109 antigen OS=Homo sapiens 1 1CD14 P08571 >sp|P08571|CD14_HUMAN Monocyte differentiation antigen CD 3 4

CD151 P48509 >sp|P48509|CD151_HUMAN CD151 antigen OS=Homo sapiens G 4 11CD163 Q86VB7 >sp|Q86VB7|C163A_HUMAN Scavenger receptor cysteine-rich ty 6 8CD209 Q9NNX6 >sp|Q9NNX6|CD209_HUMAN CD209 antigen OS=Homo sapiens 1 1CD248 Q9HCU0 >sp|Q9HCU0|CD248_HUMAN Endosialin OS=Homo sapiens GN=C 1 1

CD300LG Q6UXG3 >sp|Q6UXG3|CLM9_HUMAN CMRF35-like molecule 9 OS=Homo s 1 1CD302 Q8IX05 >sp|Q8IX05|CD302_HUMAN CD302 antigen OS=Homo sapiens G 1 1CD34 P28906 >sp|P28906|CD34_HUMAN Hematopoietic progenitor cell antige 3 3CD36 P16671 >sp|P16671|CD36_HUMAN Platelet glycoprotein 4 OS=Homo sap 16 218CD44 P16070 >sp|P16070|CD44_HUMAN CD44 antigen OS=Homo sapiens GN= 2 6CD47 Q08722 >sp|Q08722|CD47_HUMAN Leukocyte surface antigen CD47 OS= 2 2CD59 P13987 >sp|P13987|CD59_HUMAN CD59 glycoprotein OS=Homo sapiens 3 23CD5L O43866 >sp|O43866|CD5L_HUMAN CD5 antigen-like OS=Homo sapiens 3 3CD63 P08962 >sp|P08962|CD63_HUMAN CD63 antigen OS=Homo sapiens GN= 1 1CD81 P60033 >sp|P60033|CD81_HUMAN CD81 antigen OS=Homo sapiens GN= 4 34CD9 P21926 >sp|P21926|CD9_HUMAN CD9 antigen OS=Homo sapiens GN=CD 3 13CD99 P14209 >sp|P14209|CD99_HUMAN CD99 antigen OS=Homo sapiens GN= 5 14

CDC25B P30305 >sp|P30305|MPIP2_HUMAN M-phase inducer phosphatase 2 OS 1 1CDC37 Q16543 >sp|Q16543|CDC37_HUMAN Hsp90 co-chaperone Cdc37 OS=Hom 4 8CDC42 P60953 >sp|P60953|CDC42_HUMAN Cell division control protein 42 ho 8 36CDH13 P55290 >sp|P55290|CAD13_HUMAN Cadherin-13 OS=Homo sapiens GN= 6 20CDH5 P33151 >sp|P33151|CADH5_HUMAN Cadherin-5 OS=Homo sapiens GN= 3 4

CDHR1 Q96JP9 >sp|Q96JP9|CDHR1_HUMAN Cadherin-related family member 1 1 1CDIPT O14735 >sp|O14735|CDIPT_HUMAN CDP-diacylglycerol--inositol 3-phosp 1 4

CDK5RAP3 Q96JB5 >sp|Q96JB5|CK5P3_HUMAN CDK5 regulatory subunit-associated 1 2CDKAL1 Q5VV42-2 >sp|Q5VV42-2|CDKAL_HUMAN Isoform 2 of Threonylcarbamoylade 1 1

CDS2 O95674 >sp|O95674|CDS2_HUMAN Phosphatidate cytidylyltransferase 3 4CDV3 Q9UKY7 >sp|Q9UKY7|CDV3_HUMAN Protein CDV3 homolog OS=Homo sa 1 2

CELF2-AS1 Q8N7Q2 >sp|Q8N7Q2|CEAS1_HUMAN Putative uncharacterized protein 1 1CEP63 Q96MT8 >sp|Q96MT8|CEP63_HUMAN Centrosomal protein of 63 kDa OS= 1 1CES1 P23141 >sp|P23141|EST1_HUMAN Liver carboxylesterase 1 OS=Homo s 31 255

CES1P1 Q9UKY3 >sp|Q9UKY3|CES1P_HUMAN Putative inactive carboxylesterase 4 50CFB P00751 >sp|P00751|CFAB_HUMAN Complement factor B OS=Homo sapie 17 57CFD P00746 >sp|P00746|CFAD_HUMAN Complement factor D OS=Homo sapi 4 7CFH P08603 >sp|P08603|CFAH_HUMAN Complement factor H OS=Homo sapi 40 108CFI P05156 >sp|P05156|CFAI_HUMAN Complement factor I OS=Homo sapien 9 15

CFL1 P23528 >sp|P23528|COF1_HUMAN Cofilin-1 OS=Homo sapiens GN=CFL1 14 76CFL2 Q9Y281 >sp|Q9Y281|COF2_HUMAN Cofilin-2 OS=Homo sapiens GN=CFL2 3 8CGB2 Q6NT52-2 >sp|Q6NT52-2|CGB2_HUMAN Isoform 2 of Choriogonadotropin sub 1 1

CHCHD3 Q9NX63 >sp|Q9NX63|CHCH3_HUMAN Coiled-coil-helix-coiled-coil-helix do 5 8CHD3 Q12873 >sp|Q12873|CHD3_HUMAN Chromodomain-helicase-DNA-binding 1 1CHID1 Q9BWS9 >sp|Q9BWS9|CHID1_HUMAN Chitinase domain-containing protei 2 3

CHMP2A O43633 >sp|O43633|CHM2A_HUMAN Charged multivesicular body prote 1 1CHMP4B Q9H444 >sp|Q9H444|CHM4B_HUMAN Charged multivesicular body prote 1 2

CHRD Q9H2X0 >sp|Q9H2X0|CHRD_HUMAN Chordin OS=Homo sapiens GN=CHR 1 1CISD1 Q9NZ45 >sp|Q9NZ45|CISD1_HUMAN CDGSH iron-sulfur domain-containing 3 4CISD2 Q8N5K1 >sp|Q8N5K1|CISD2_HUMAN CDGSH iron-sulfur domain-containin 1 2CKAP4 Q07065 >sp|Q07065|CKAP4_HUMAN Cytoskeleton-associated protein 4 8 9

CKB P12277 >sp|P12277|KCRB_HUMAN Creatine kinase B-type OS=Homo sap 15 65CKMT1A P12532 >sp|P12532|KCRU_HUMAN Creatine kinase U-type, mitochondri 1 2CLCC1 Q96S66 >sp|Q96S66|CLCC1_HUMAN Chloride channel CLIC-like protein 1 1CLDN5 O00501 >sp|O00501|CLD5_HUMAN Claudin-5 OS=Homo sapiens GN=CLD 1 1

CLEC14A Q86T13 >sp|Q86T13|CLC14_HUMAN C-type lectin domain family 14 mem 1 1CLEC3B P05452 >sp|P05452|TETN_HUMAN Tetranectin OS=Homo sapiens GN=C 5 22

CLIC1 O00299 >sp|O00299|CLIC1_HUMAN Chloride intracellular channel protei 11 32CLIC3 O95833 >sp|O95833|CLIC3_HUMAN Chloride intracellular channel protei 1 1CLIC4 Q9Y696 >sp|Q9Y696|CLIC4_HUMAN Chloride intracellular channel prote 4 6

CLINT1 Q14677 >sp|Q14677|EPN4_HUMAN Clathrin interactor 1 OS=Homo sapie 1 1CLTA P09496 >sp|P09496|CLCA_HUMAN Clathrin light chain A OS=Homo sapi 1 3CLTA P09496-2 >sp|P09496-2|CLCA_HUMAN Isoform Non-brain of Clathrin light 1 7CLTB P09497 >sp|P09497|CLCB_HUMAN Clathrin light chain B OS=Homo sapi 3 9

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CLTC Q00610 >sp|Q00610|CLH1_HUMAN Clathrin heavy chain 1 OS=Homo sap 53 155CLU P10909 >sp|P10909|CLUS_HUMAN Clusterin OS=Homo sapiens GN=CLU 9 41

CLUH O75153 >sp|O75153|CLU_HUMAN Clustered mitochondria protein homol 1 2CMA1 P23946 >sp|P23946|CMA1_HUMAN Chymase OS=Homo sapiens GN=CMA 3 5CMBL Q96DG6 >sp|Q96DG6|CMBL_HUMAN Carboxymethylenebutenolidase hom 2 3

CMPK1 P30085 >sp|P30085|KCY_HUMAN UMP-CMP kinase OS=Homo sapiens 5 13CMTM7 Q96FZ5 >sp|Q96FZ5|CKLF7_HUMAN CKLF-like MARVEL transmembrane do 1 1CNBP P62633 >sp|P62633|CNBP_HUMAN Cellular nucleic acid-binding protei 1 3

CNDP2 Q96KP4 >sp|Q96KP4|CNDP2_HUMAN Cytosolic non-specific dipeptidase 10 31CNN1 P51911 >sp|P51911|CNN1_HUMAN Calponin-1 OS=Homo sapiens GN=CN 2 5CNN2 Q99439 >sp|Q99439|CNN2_HUMAN Calponin-2 OS=Homo sapiens GN=CN 1 2CNN3 Q15417 >sp|Q15417|CNN3_HUMAN Calponin-3 OS=Homo sapiens GN=CN 2 2CNP P09543 >sp|P09543|CN37_HUMAN 2',3'-cyclic-nucleotide 3'-phosphodie 5 7

CNPY2 Q9Y2B0 >sp|Q9Y2B0|CNPY2_HUMAN Protein canopy homolog 2 OS=Hom 2 3CNRIP1 Q96F85 >sp|Q96F85|CNRP1_HUMAN CB1 cannabinoid receptor-interactin 2 5CNTFR P26992 >sp|P26992|CNTFR_HUMAN Ciliary neurotrophic factor receptor 1 1

COBLL1 Q53SF7 >sp|Q53SF7|COBL1_HUMAN Cordon-bleu protein-like 1 OS=Hom 1 1COIL P38432 >sp|P38432|COIL_HUMAN Coilin OS=Homo sapiens GN=COIL PE 1 1

COL14A1 Q05707 >sp|Q05707|COEA1_HUMAN Collagen alpha-1(XIV) chain OS=Ho 41 95COL15A1 P39059 >sp|P39059|COFA1_HUMAN Collagen alpha-1(XV) chain OS=Ho 6 13COL18A1 P39060 >sp|P39060|COIA1_HUMAN Collagen alpha-1(XVIII) chain OS=H 14 35COL1A1 D3DTX7 >tr|D3DTX7|D3DTX7_HUMAN Collagen, type I, alpha 1, isofor 1 5COL1A1 P02452 >sp|P02452|CO1A1_HUMAN Collagen alpha-1(I) chain OS=Homo 4 14COL1A2 P08123 >sp|P08123|CO1A2_HUMAN Collagen alpha-2(I) chain OS=Homo 8 21COL2A1 P02458 >sp|P02458|CO2A1_HUMAN Collagen alpha-1(II) chain OS=Hom 1 3COL3A1 P02461 >sp|P02461|CO3A1_HUMAN Collagen alpha-1(III) chain OS=Hom 1 1COL4A1 P02462 >sp|P02462|CO4A1_HUMAN Collagen alpha-1(IV) chain OS=Hom 4 9COL4A2 P08572 >sp|P08572|CO4A2_HUMAN Collagen alpha-2(IV) chain OS=Hom 3 3COL6A1 P12109 >sp|P12109|CO6A1_HUMAN Collagen alpha-1(VI) chain OS=Hom 15 37COL6A2 P12110 >sp|P12110|CO6A2_HUMAN Collagen alpha-2(VI) chain OS=Hom 9 15COL6A2 P12110-2 >sp|P12110-2|CO6A2_HUMAN Isoform 2C2A of Collagen alpha-2( 1 1COL6A3 P12111 >sp|P12111|CO6A3_HUMAN Collagen alpha-3(VI) chain OS=Hom 60 199COL6A3 P12111-4 >sp|P12111-4|CO6A3_HUMAN Isoform 4 of Collagen alpha-3(VI) 1 2COL7A1 Q02388 >sp|Q02388|CO7A1_HUMAN Collagen alpha-1(VII) chain OS=Ho 1 2COMMD2 Q86X83 >sp|Q86X83|COMD2_HUMAN COMM domain-containing protein 1 1COMMD3 Q9UBI1 >sp|Q9UBI1|COMD3_HUMAN COMM domain-containing protein 1 2

COMT P21964 >sp|P21964|COMT_HUMAN Catechol O-methyltransferase OS=H 6 12COPA P53621 >sp|P53621|COPA_HUMAN Coatomer subunit alpha OS=Homo sa 7 8

COPB1 P53618 >sp|P53618|COPB_HUMAN Coatomer subunit beta OS=Homo sap 6 9COPB2 P35606 >sp|P35606|COPB2_HUMAN Coatomer subunit beta' OS=Homo s 4 6COPE O14579 >sp|O14579|COPE_HUMAN Coatomer subunit epsilon OS=Homo 2 2

COPG1 Q9Y678 >sp|Q9Y678|COPG1_HUMAN Coatomer subunit gamma-1 OS=Ho 4 6COPS2 P61201 >sp|P61201|CSN2_HUMAN COP9 signalosome complex subunit 2 2COPS3 Q9UNS2 >sp|Q9UNS2|CSN3_HUMAN COP9 signalosome complex subunit 2 2COPS4 Q9BT78 >sp|Q9BT78|CSN4_HUMAN COP9 signalosome complex subunit 2 3COPS5 Q92905 >sp|Q92905|CSN5_HUMAN COP9 signalosome complex subunit 1 1COPS6 Q7L5N1 >sp|Q7L5N1|CSN6_HUMAN COP9 signalosome complex subunit 1 2COPS8 Q99627 >sp|Q99627|CSN8_HUMAN COP9 signalosome complex subunit 3 4COPZ1 P61923 >sp|P61923|COPZ1_HUMAN Coatomer subunit zeta-1 OS=Homo 1 1COQ9 O75208 >sp|O75208|COQ9_HUMAN Ubiquinone biosynthesis protein COQ 1 2

CORO1A P31146 >sp|P31146|COR1A_HUMAN Coronin-1A OS=Homo sapiens GN= 5 9CORO1B Q9BR76 >sp|Q9BR76|COR1B_HUMAN Coronin-1B OS=Homo sapiens GN 1 1CORO1C Q9ULV4 >sp|Q9ULV4|COR1C_HUMAN Coronin-1C OS=Homo sapiens GN 7 18COTL1 Q14019 >sp|Q14019|COTL1_HUMAN Coactosin-like protein OS=Homo sa 5 10COX4I1 P13073 >sp|P13073|COX41_HUMAN Cytochrome c oxidase subunit 4 isof 5 16COX5A P20674 >sp|P20674|COX5A_HUMAN Cytochrome c oxidase subunit 5A, m 6 18COX5B P10606 >sp|P10606|COX5B_HUMAN Cytochrome c oxidase subunit 5B, m 2 2COX6B1 P14854 >sp|P14854|CX6B1_HUMAN Cytochrome c oxidase subunit 6B1 1 1COX6C P09669 >sp|P09669|COX6C_HUMAN Cytochrome c oxidase subunit 6C 2 6COX7A1 P24310 >sp|P24310|CX7A1_HUMAN Cytochrome c oxidase subunit 7A1, 1 4COX7A2 P14406 >sp|P14406|CX7A2_HUMAN Cytochrome c oxidase subunit 7A2, 2 9

CP P00450 >sp|P00450|CERU_HUMAN Ceruloplasmin OS=Homo sapiens GN 33 156CPA3 P15088 >sp|P15088|CBPA3_HUMAN Mast cell carboxypeptidase A OS=H 3 6CPD O75976 >sp|O75976|CBPD_HUMAN Carboxypeptidase D OS=Homo sapie 1 1

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CPM P14384 >sp|P14384|CBPM_HUMAN Carboxypeptidase M OS=Homo sapie 2 3CPN2 P22792 >sp|P22792|CPN2_HUMAN Carboxypeptidase N subunit 2 OS=Ho 2 3

CPNE1 Q99829 >sp|Q99829|CPNE1_HUMAN Copine-1 OS=Homo sapiens GN=CP 2 2CPNE2 Q96FN4 >sp|Q96FN4|CPNE2_HUMAN Copine-2 OS=Homo sapiens GN=CP 1 5CPNE3 O75131 >sp|O75131|CPNE3_HUMAN Copine-3 OS=Homo sapiens GN=CP 5 10CPT2 P23786 >sp|P23786|CPT2_HUMAN Carnitine O-palmitoyltransferase 2, m 1 2

CREB3L4 Q8TEY5 >sp|Q8TEY5|CR3L4_HUMAN Cyclic AMP-responsive element-bindin 1 17CRELD1 Q96HD1 >sp|Q96HD1|CREL1_HUMAN Cysteine-rich with EGF-like domain 1 1

CRHR1-IT1 Q96LR1 >sp|Q96LR1|CRIT1_HUMAN Putative uncharacterized protein e 1 1CRIP1 P50238 >sp|P50238|CRIP1_HUMAN Cysteine-rich protein 1 OS=Homo sa 1 2CRIP2 P52943 >sp|P52943|CRIP2_HUMAN Cysteine-rich protein 2 OS=Homo sa 2 5CRK P46108 >sp|P46108|CRK_HUMAN Adapter molecule crk OS=Homo sapie 2 5CRK P46108-2 >sp|P46108-2|CRK_HUMAN Isoform Crk-I of Adapter molecule c 1 1

CRMP1 Q14194 >sp|Q14194|DPYL1_HUMAN Dihydropyrimidinase-related protei 4 16CRYAB P02511 >sp|P02511|CRYAB_HUMAN Alpha-crystallin B chain OS=Homo 15 344CRYL1 Q9Y2S2 >sp|Q9Y2S2|CRYL1_HUMAN Lambda-crystallin homolog OS=Hom 1 1CRYZ Q08257 >sp|Q08257|QOR_HUMAN Quinone oxidoreductase OS=Homo sa 3 3

CS O75390 >sp|O75390|CISY_HUMAN Citrate synthase, mitochondrial OS=H 12 71CSDE1 O75534 >sp|O75534|CSDE1_HUMAN Cold shock domain-containing prot 1 2CSE1L P55060 >sp|P55060|XPO2_HUMAN Exportin-2 OS=Homo sapiens GN=CS 1 2

CSGALNACT1 Q8TDX6 >sp|Q8TDX6|CGAT1_HUMAN Chondroitin sulfate N-acetylgalact 1 1CSNK2B P67870 >sp|P67870|CSK2B_HUMAN Casein kinase II subunit beta OS=H 1 1CSPG4 Q6UVK1 >sp|Q6UVK1|CSPG4_HUMAN Chondroitin sulfate proteoglycan 3 3CSRP1 P21291 >sp|P21291|CSRP1_HUMAN Cysteine and glycine-rich protein 7 31CST3 P01034 >sp|P01034|CYTC_HUMAN Cystatin-C OS=Homo sapiens GN=CS 2 2CSTB P04080 >sp|P04080|CYTB_HUMAN Cystatin-B OS=Homo sapiens GN=CS 4 24

CTNNA1 P35221 >sp|P35221|CTNA1_HUMAN Catenin alpha-1 OS=Homo sapiens 2 5CTNNB1 P35222 >sp|P35222|CTNB1_HUMAN Catenin beta-1 OS=Homo sapiens 2 2CTNND1 O60716 >sp|O60716|CTND1_HUMAN Catenin delta-1 OS=Homo sapiens 1 2

CTSB P07858 >sp|P07858|CATB_HUMAN Cathepsin B OS=Homo sapiens GN=C 5 9CTSC P53634 >sp|P53634|CATC_HUMAN Dipeptidyl peptidase 1 OS=Homo sap 2 5CTSD P07339 >sp|P07339|CATD_HUMAN Cathepsin D OS=Homo sapiens GN=C 16 91CTSG P08311 >sp|P08311|CATG_HUMAN Cathepsin G OS=Homo sapiens GN= 4 12CTSZ Q9UBR2 >sp|Q9UBR2|CATZ_HUMAN Cathepsin Z OS=Homo sapiens GN= 1 4CTTN Q14247 >sp|Q14247|SRC8_HUMAN Src substrate cortactin OS=Homo sa 3 4

CTTNBP2NL Q9P2B4 >sp|Q9P2B4|CT2NL_HUMAN CTTNBP2 N-terminal-like protein 1 1CUL3 Q13618 >sp|Q13618|CUL3_HUMAN Cullin-3 OS=Homo sapiens GN=CUL3 1 1CUTA O60888 >sp|O60888|CUTA_HUMAN Protein CutA OS=Homo sapiens GN= 4 7

CYB5A P00167 >sp|P00167|CYB5_HUMAN Cytochrome b5 OS=Homo sapiens G 5 34CYB5B O43169 >sp|O43169|CYB5B_HUMAN Cytochrome b5 type B OS=Homo sa 1 2CYB5R1 Q9UHQ9 >sp|Q9UHQ9|NB5R1_HUMAN NADH-cytochrome b5 reductase 1 6 14CYB5R3 P00387 >sp|P00387|NB5R3_HUMAN NADH-cytochrome b5 reductase 3 O 20 113CYBB P04839 >sp|P04839|CY24B_HUMAN Cytochrome b-245 heavy chain OS= 3 3

CYBRD1 Q53TN4 >sp|Q53TN4|CYBR1_HUMAN Cytochrome b reductase 1 OS=Hom 2 4CYC1 P08574 >sp|P08574|CY1_HUMAN Cytochrome c1, heme protein, mitocho 5 11CYCS P99999 >sp|P99999|CYC_HUMAN Cytochrome c OS=Homo sapiens GN= 9 26

CYFIP1 Q7L576 >sp|Q7L576|CYFP1_HUMAN Cytoplasmic FMR1-interacting prote 2 2CYGB Q8WWM9 >sp|Q8WWM9|CYGB_HUMAN Cytoglobin OS=Homo sapiens GN= 1 1

CYP51A1 Q16850 >sp|Q16850|CP51A_HUMAN Lanosterol 14-alpha demethylase O 1 1CYTH1 Q15438 >sp|Q15438|CYH1_HUMAN Cytohesin-1 OS=Homo sapiens GN=C 1 1DAD1 P61803 >sp|P61803|DAD1_HUMAN Dolichyl-diphosphooligosaccharide--pr 1 1DAG1 Q14118 >sp|Q14118|DAG1_HUMAN Dystroglycan OS=Homo sapiens GN= 1 3DAK Q3LXA3 >sp|Q3LXA3|DHAK_HUMAN Bifunctional ATP-dependent dihydroxy 2 3

DARS P14868 >sp|P14868|SYDC_HUMAN Aspartate--tRNA ligase, cytoplasmic 5 6DARS2 Q6PI48 >sp|Q6PI48|SYDM_HUMAN Aspartate--tRNA ligase, mitochondri 1 1

DBI P07108 >sp|P07108|ACBP_HUMAN Acyl-CoA-binding protein OS=Homo s 7 47DBNL Q9UJU6 >sp|Q9UJU6|DBNL_HUMAN Drebrin-like protein OS=Homo sapie 4 9DBT P11182 >sp|P11182|ODB2_HUMAN Lipoamide acyltransferase component of 2 2

DCDC1 H0Y2Q8 >tr|H0Y2Q8|H0Y2Q8_HUMAN Doublecortin domain-containing pro 1 2DCN P07585 >sp|P07585|PGS2_HUMAN Decorin OS=Homo sapiens GN=DCN 18 173

DCPS Q96C86 >sp|Q96C86|DCPS_HUMAN m7GpppX diphosphatase OS=Homo s 1 1DCTN1 Q14203 >sp|Q14203|DCTN1_HUMAN Dynactin subunit 1 OS=Homo sapie 9 17DCTN1 Q14203-5 >sp|Q14203-5|DCTN1_HUMAN Isoform 5 of Dynactin subunit 1 1 3DCTN2 Q13561 >sp|Q13561|DCTN2_HUMAN Dynactin subunit 2 OS=Homo sapie 14 35

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DCTN4 Q9UJW0 >sp|Q9UJW0|DCTN4_HUMAN Dynactin subunit 4 OS=Homo sapi 1 1DCUN1D3 Q8IWE4 >sp|Q8IWE4|DCNL3_HUMAN DCN1-like protein 3 OS=Homo sap 2 3DCUN1D5 Q9BTE7 >sp|Q9BTE7|DCNL5_HUMAN DCN1-like protein 5 OS=Homo sap 1 1

DCXR Q7Z4W1 >sp|Q7Z4W1|DCXR_HUMAN L-xylulose reductase OS=Homo sap 6 14DDAH1 O94760 >sp|O94760|DDAH1_HUMAN N(G),N(G)-dimethylarginine dimethy 2 4DDAH2 O95865 >sp|O95865|DDAH2_HUMAN N(G),N(G)-dimethylarginine dimethy 10 48DDB1 Q16531 >sp|Q16531|DDB1_HUMAN DNA damage-binding protein 1 OS=H 7 12

DDOST P39656 >sp|P39656|OST48_HUMAN Dolichyl-diphosphooligosaccharide--p 8 17DDRGK1 Q96HY6 >sp|Q96HY6|DDRGK_HUMAN DDRGK domain-containing protein 1 1

DDT J3KQ18 >tr|J3KQ18|J3KQ18_HUMAN D-dopachrome decarboxylase OS=H 1 1DDT P30046 >sp|P30046|DOPD_HUMAN D-dopachrome decarboxylase OS=Ho 1 8

DDTL A6NHG4 >sp|A6NHG4|DDTL_HUMAN D-dopachrome decarboxylase-like pr 4 9DDX1 Q92499 >sp|Q92499|DDX1_HUMAN ATP-dependent RNA helicase DDX1 3 4DDX17 Q92841 >sp|Q92841|DDX17_HUMAN Probable ATP-dependent RNA helic 2 2

DDX19A Q9NUU7 >sp|Q9NUU7|DD19A_HUMAN ATP-dependent RNA helicase DDX 2 3DDX39A O00148 >sp|O00148|DX39A_HUMAN ATP-dependent RNA helicase DDX3 4 5DDX39B Q13838 >sp|Q13838|DX39B_HUMAN Spliceosome RNA helicase DDX39B 2 4DDX55 Q8NHQ9 >sp|Q8NHQ9|DDX55_HUMAN ATP-dependent RNA helicase DDX 1 1DDX6 P26196 >sp|P26196|DDX6_HUMAN Probable ATP-dependent RNA helica 1 1

DECR1 Q16698 >sp|Q16698|DECR_HUMAN 2,4-dienoyl-CoA reductase, mitochon 8 32DEFA1 P59665 >sp|P59665|DEF1_HUMAN Neutrophil defensin 1 OS=Homo sapi 2 3

DENND4A Q7Z401 >sp|Q7Z401|MYCPP_HUMAN C-myc promoter-binding protein O 1 1DENR O43583 >sp|O43583|DENR_HUMAN Density-regulated protein OS=Homo 2 4DERA Q9Y315 >sp|Q9Y315|DEOC_HUMAN Putative deoxyribose-phosphate ald 1 1DERL1 Q9BUN8 >sp|Q9BUN8|DERL1_HUMAN Derlin-1 OS=Homo sapiens GN=DE 1 2

DES P17661 >sp|P17661|DESM_HUMAN Desmin OS=Homo sapiens GN=DES 5 51DGKG P49619 >sp|P49619|DGKG_HUMAN Diacylglycerol kinase gamma OS=Ho 1 1DHRS1 Q96LJ7 >sp|Q96LJ7|DHRS1_HUMAN Dehydrogenase/reductase SDR fami 2 2DHRS7 Q9Y394 >sp|Q9Y394|DHRS7_HUMAN Dehydrogenase/reductase SDR fami 2 4

DHRS7B Q6IAN0 >sp|Q6IAN0|DRS7B_HUMAN Dehydrogenase/reductase SDR fami 1 1DHX30 Q7L2E3 >sp|Q7L2E3|DHX30_HUMAN Putative ATP-dependent RNA helic 1 2DHX9 Q08211 >sp|Q08211|DHX9_HUMAN ATP-dependent RNA helicase A OS= 3 3

DIABLO Q9NR28 >sp|Q9NR28|DBLOH_HUMAN Diablo homolog, mitochondrial OS 1 2DKFZp434E2321Q9UF43 >tr|Q9UF43|Q9UF43_HUMAN Putative uncharacterized protein 1 1DKFZp666M0710Q658W4 >tr|Q658W4|Q658W4_HUMAN Putative uncharacterized protein 1 1DKFZp686A0568Q5CZ93 >tr|Q5CZ93|Q5CZ93_HUMAN Putative uncharacterized protein 1 1

DKFZp686C15213Q6MZU6 >tr|Q6MZU6|Q6MZU6_HUMAN Putative uncharacterized protein 2 20DKFZp686G11190Q6MZQ6 >tr|Q6MZQ6|Q6MZQ6_HUMAN Putative uncharacterized protei 1 1DKFZp686I04196Q6N093 >tr|Q6N093|Q6N093_HUMAN Putative uncharacterized protein D 1 1DKFZp686K04218Q7Z379 >tr|Q7Z379|Q7Z379_HUMAN Putative uncharacterized protein 1 1DKFZp686M0430Q5CZB5 >tr|Q5CZB5|Q5CZB5_HUMAN Putative uncharacterized protein 3 15DKFZp686N02209Q7Z351 >tr|Q7Z351|Q7Z351_HUMAN Putative uncharacterized protein 1 2DKFZp686P15220Q6N089 >tr|Q6N089|Q6N089_HUMAN Putative uncharacterized protein 2 2

DLAT P10515 >sp|P10515|ODP2_HUMAN Dihydrolipoyllysine-residue acetyltran 6 18DLD P09622 >sp|P09622|DLDH_HUMAN Dihydrolipoyl dehydrogenase, mitoch 12 30

DLG5 Q8TDM6 >sp|Q8TDM6|DLG5_HUMAN Disks large homolog 5 OS=Homo sap 1 2DLGAP4 Q9Y2H0 >sp|Q9Y2H0|DLGP4_HUMAN Disks large-associated protein 4 1 3

DLST P36957 >sp|P36957|ODO2_HUMAN Dihydrolipoyllysine-residue succinyltra 8 36DMD P11532 >sp|P11532|DMD_HUMAN Dystrophin OS=Homo sapiens GN=DM 2 2

DNAJA1 P31689 >sp|P31689|DNJA1_HUMAN DnaJ homolog subfamily A member 1 1DNAJA2 O60884 >sp|O60884|DNJA2_HUMAN DnaJ homolog subfamily A member 4 8DNAJA3 Q96EY1 >sp|Q96EY1|DNJA3_HUMAN DnaJ homolog subfamily A member 3 1 1DNAJB1 P25685 >sp|P25685|DNJB1_HUMAN DnaJ homolog subfamily B member 2 2

DNAJB11 Q9UBS4 >sp|Q9UBS4|DJB11_HUMAN DnaJ homolog subfamily B member 1 1DNAJB2 P25686 >sp|P25686|DNJB2_HUMAN DnaJ homolog subfamily B member 1 1

DNAJC17 Q9NVM6 >sp|Q9NVM6|DJC17_HUMAN DnaJ homolog subfamily C member 1 1DNAJC8 O75937 >sp|O75937|DNJC8_HUMAN DnaJ homolog subfamily C member 1 2DNALI1 O14645 >sp|O14645|IDLC_HUMAN Axonemal dynein light intermediate po 1 1DNM1 Q05193 >sp|Q05193|DYN1_HUMAN Dynamin-1 OS=Homo sapiens GN=DN 3 7

DNM1L O00429 >sp|O00429|DNM1L_HUMAN Dynamin-1-like protein OS=Homo s 4 4DNM2 P50570 >sp|P50570|DYN2_HUMAN Dynamin-2 OS=Homo sapiens GN=DN 1 2

DNPEP Q9ULA0 >sp|Q9ULA0|DNPEP_HUMAN Aspartyl aminopeptidase OS=Homo 4 6DNPH1 O43598 >sp|O43598|DNPH1_HUMAN 2'-deoxynucleoside 5'-phosphate N- 3 3DOCK7 Q96N67 >sp|Q96N67|DOCK7_HUMAN Dedicator of cytokinesis protein 7 1 1

Page 11: [XLS]media.nature.com · Web viewSupp-Table S2B Supp-Table S2A Gene name UniProt accession Fasta protein description Unique peptides Spectral counts A1BG P04217 >sp|P04217|A1BG_HUMAN

DPM1 O60762 >sp|O60762|DPM1_HUMAN Dolichol-phosphate mannosyltransfer 1 1DPP3 Q9NY33 >sp|Q9NY33|DPP3_HUMAN Dipeptidyl peptidase 3 OS=Homo sap 2 2DPP4 P27487 >sp|P27487|DPP4_HUMAN Dipeptidyl peptidase 4 OS=Homo sap 2 2DPT Q07507 >sp|Q07507|DERM_HUMAN Dermatopontin OS=Homo sapiens G 4 13

DPYSL2 Q16555 >sp|Q16555|DPYL2_HUMAN Dihydropyrimidinase-related protei 20 70DPYSL3 Q14195 >sp|Q14195|DPYL3_HUMAN Dihydropyrimidinase-related protei 11 23DPYSL3 Q14195-2 >sp|Q14195-2|DPYL3_HUMAN Isoform LCRMP-4 of Dihydropyrimid 2 6

DRG2 P55039 >sp|P55039|DRG2_HUMAN Developmentally-regulated GTP-bindi 1 3DROSHA Q9NRR4 >sp|Q9NRR4|RNC_HUMAN Ribonuclease 3 OS=Homo sapiens G 1 1

DSC1 Q08554 >sp|Q08554|DSC1_HUMAN Desmocollin-1 OS=Homo sapiens GN 1 2DST Q03001 >sp|Q03001|DYST_HUMAN Dystonin OS=Homo sapiens GN=DST 1 3

DSTN P60981 >sp|P60981|DEST_HUMAN Destrin OS=Homo sapiens GN=DSTN 7 16DUSP3 P51452 >sp|P51452|DUS3_HUMAN Dual specificity protein phosphatase 2 5

DYNC1H1 Q14204 >sp|Q14204|DYHC1_HUMAN Cytoplasmic dynein 1 heavy chain 63 120DYNC1I2 Q13409 >sp|Q13409|DC1I2_HUMAN Cytoplasmic dynein 1 intermediate c 6 10DYNC1I2 Q13409-2 >sp|Q13409-2|DC1I2_HUMAN Isoform 2B of Cytoplasmic dynein 1 2 6

DYNC1LI1 Q9Y6G9 >sp|Q9Y6G9|DC1L1_HUMAN Cytoplasmic dynein 1 light intermed 1 2DYNC1LI2 O43237 >sp|O43237|DC1L2_HUMAN Cytoplasmic dynein 1 light intermed 5 7DYNLL1 P63167 >sp|P63167|DYL1_HUMAN Dynein light chain 1, cytoplasmic OS 4 10DYNLL2 Q96FJ2 >sp|Q96FJ2|DYL2_HUMAN Dynein light chain 2, cytoplasmic O 3 8

DYNLRB1 Q9NP97 >sp|Q9NP97|DLRB1_HUMAN Dynein light chain roadblock-type 2 4DYNLT3 P51808 >sp|P51808|DYLT3_HUMAN Dynein light chain Tctex-type 3 OS 1 2

DYSF O75923 >sp|O75923|DYSF_HUMAN Dysferlin OS=Homo sapiens GN=DYS 2 2ECH1 Q13011 >sp|Q13011|ECH1_HUMAN Delta(3,5)-Delta(2,4)-dienoyl-CoA iso 12 28

ECHDC1 Q9NTX5 >sp|Q9NTX5|ECHD1_HUMAN Ethylmalonyl-CoA decarboxylase 10 24ECHDC3 Q96DC8 >sp|Q96DC8|ECHD3_HUMAN Enoyl-CoA hydratase domain-containi 5 5ECHS1 P30084 >sp|P30084|ECHM_HUMAN Enoyl-CoA hydratase, mitochondrial 19 60

ECI1 P42126 >sp|P42126|ECI1_HUMAN Enoyl-CoA delta isomerase 1, mitocho 4 9ECI2 O75521 >sp|O75521|ECI2_HUMAN Enoyl-CoA delta isomerase 2, mitocho 1 2ECM1 Q16610 >sp|Q16610|ECM1_HUMAN Extracellular matrix protein 1 OS=H 2 2EDC4 Q6P2E9 >sp|Q6P2E9|EDC4_HUMAN Enhancer of mRNA-decapping protei 1 1EDF1 O60869 >sp|O60869|EDF1_HUMAN Endothelial differentiation-related fa 1 1EEA1 Q15075 >sp|Q15075|EEA1_HUMAN Early endosome antigen 1 OS=Homo 14 23

EEF1A1 P68104 >sp|P68104|EF1A1_HUMAN Elongation factor 1-alpha 1 OS=Hom 26 205EEF1B2 P24534 >sp|P24534|EF1B_HUMAN Elongation factor 1-beta OS=Homo sa 5 14EEF1D P29692 >sp|P29692|EF1D_HUMAN Elongation factor 1-delta OS=Homo s 4 10EEF1G P26641 >sp|P26641|EF1G_HUMAN Elongation factor 1-gamma OS=Homo 9 20EEF2 P13639 >sp|P13639|EF2_HUMAN Elongation factor 2 OS=Homo sapiens 30 95

EFEMP1 Q12805 >sp|Q12805|FBLN3_HUMAN EGF-containing fibulin-like extracell 4 10EFHD1 Q9BUP0 >sp|Q9BUP0|EFHD1_HUMAN EF-hand domain-containing protein 1 1EFHD2 Q96C19 >sp|Q96C19|EFHD2_HUMAN EF-hand domain-containing protein 1 1EFR3B Q9Y2G0 >sp|Q9Y2G0|EFR3B_HUMAN Protein EFR3 homolog B OS=Homo 1 1EGFR P00533 >sp|P00533|EGFR_HUMAN Epidermal growth factor receptor OS 1 2

EGLN2 Q96KS0 >sp|Q96KS0|EGLN2_HUMAN Egl nine homolog 2 OS=Homo sapi 1 1EHBP1L1 Q8N3D4 >sp|Q8N3D4|EH1L1_HUMAN EH domain-binding protein 1-like pr 1 1

EHD1 Q9H4M9 >sp|Q9H4M9|EHD1_HUMAN EH domain-containing protein 1 OS= 14 62EHD2 Q9NZN4 >sp|Q9NZN4|EHD2_HUMAN EH domain-containing protein 2 OS= 53 521EHD3 Q9NZN3 >sp|Q9NZN3|EHD3_HUMAN EH domain-containing protein 3 OS= 1 2EHD4 Q9H223 >sp|Q9H223|EHD4_HUMAN EH domain-containing protein 4 OS= 10 21EHF Q9NZC4 >sp|Q9NZC4|EHF_HUMAN ETS homologous factor OS=Homo sap 1 1

EHHADH Q08426 >sp|Q08426|ECHP_HUMAN Peroxisomal bifunctional enzyme O 2 2EIF1AX P47813 >sp|P47813|IF1AX_HUMAN Eukaryotic translation initiation fac 1 1

EIF2AK4 Q9P2K8 >sp|Q9P2K8|E2AK4_HUMAN Eukaryotic translation initiation fact 1 1EIF2S1 P05198 >sp|P05198|IF2A_HUMAN Eukaryotic translation initiation factor 3 5EIF2S3 P41091 >sp|P41091|IF2G_HUMAN Eukaryotic translation initiation factor 2 4

EIF2S3L Q2VIR3 >sp|Q2VIR3|IF2GL_HUMAN Putative eukaryotic translation initiati 1 1EIF3A Q14152 >sp|Q14152|EIF3A_HUMAN Eukaryotic translation initiation fact 3 4EIF3B P55884 >sp|P55884|EIF3B_HUMAN Eukaryotic translation initiation fact 2 5EIF3C Q99613 >sp|Q99613|EIF3C_HUMAN Eukaryotic translation initiation fact 2 5EIF3D O15371 >sp|O15371|EIF3D_HUMAN Eukaryotic translation initiation fact 2 3EIF3F O00303 >sp|O00303|EIF3F_HUMAN Eukaryotic translation initiation facto 2 2EIF3G O75821 >sp|O75821|EIF3G_HUMAN Eukaryotic translation initiation fact 1 3EIF3H O15372 >sp|O15372|EIF3H_HUMAN Eukaryotic translation initiation fact 2 4EIF3I Q13347 >sp|Q13347|EIF3I_HUMAN Eukaryotic translation initiation factor 1 1

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EIF3K Q9UBQ5 >sp|Q9UBQ5|EIF3K_HUMAN Eukaryotic translation initiation fact 2 3EIF3L Q9Y262 >sp|Q9Y262|EIF3L_HUMAN Eukaryotic translation initiation facto 1 1

EIF4A1 P60842 >sp|P60842|IF4A1_HUMAN Eukaryotic initiation factor 4A-I OS= 13 47EIF4A2 Q14240 >sp|Q14240|IF4A2_HUMAN Eukaryotic initiation factor 4A-II OS 3 6EIF4A3 P38919 >sp|P38919|IF4A3_HUMAN Eukaryotic initiation factor 4A-III O 2 2EIF4B P23588 >sp|P23588|IF4B_HUMAN Eukaryotic translation initiation facto 2 2EIF4E P06730 >sp|P06730|IF4E_HUMAN Eukaryotic translation initiation facto 2 2

EIF4G1 Q04637 >sp|Q04637|IF4G1_HUMAN Eukaryotic translation initiation fac 5 5EIF4H Q15056 >sp|Q15056|IF4H_HUMAN Eukaryotic translation initiation facto 2 2EIF5 P55010 >sp|P55010|IF5_HUMAN Eukaryotic translation initiation factor 1 2

EIF5A P63241 >sp|P63241|IF5A1_HUMAN Eukaryotic translation initiation fact 7 35EIF5B O60841 >sp|O60841|IF2P_HUMAN Eukaryotic translation initiation facto 1 1EIF6 P56537 >sp|P56537|IF6_HUMAN Eukaryotic translation initiation factor 1 5

ELANE P08246 >sp|P08246|ELNE_HUMAN Neutrophil elastase OS=Homo sapien 3 4ELMO1 Q92556 >sp|Q92556|ELMO1_HUMAN Engulfment and cell motility protei 1 1

ELMSAN1 Q6PJG2 >sp|Q6PJG2|EMSA1_HUMAN ELM2 and SANT domain-containing 1 1EMC2 Q15006 >sp|Q15006|EMC2_HUMAN ER membrane protein complex subun 2 2EMC4 Q5J8M3 >sp|Q5J8M3|EMC4_HUMAN ER membrane protein complex subun 1 1EMID1 Q96A84 >sp|Q96A84|EMID1_HUMAN EMI domain-containing protein 1 O 1 1EML2 O95834 >sp|O95834|EMAL2_HUMAN Echinoderm microtubule-associated p 1 1EML6 Q6ZMW3 >sp|Q6ZMW3|EMAL6_HUMAN Echinoderm microtubule-associated 1 1EMP2 P54851 >sp|P54851|EMP2_HUMAN Epithelial membrane protein 2 OS=H 1 2EMR1 Q14246 >sp|Q14246|EMR1_HUMAN EGF-like module-containing mucin-lik 1 2EN2 P19622 >sp|P19622|HME2_HUMAN Homeobox protein engrailed-2 OS=Ho 1 1

ENAH Q8N8S7 >sp|Q8N8S7|ENAH_HUMAN Protein enabled homolog OS=Homo 1 5ENDOD1 O94919 >sp|O94919|ENDD1_HUMAN Endonuclease domain-containing 1 1 1

ENO1 P06733 >sp|P06733|ENOA_HUMAN Alpha-enolase OS=Homo sapiens GN 39 298ENO2 P09104 >sp|P09104|ENOG_HUMAN Gamma-enolase OS=Homo sapiens 1 1ENO3 P13929 >sp|P13929|ENOB_HUMAN Beta-enolase OS=Homo sapiens GN= 1 2ENSA O43768 >sp|O43768|ENSA_HUMAN Alpha-endosulfine OS=Homo sapiens 1 1EPB41 P11171 >sp|P11171|41_HUMAN Protein 4.1 OS=Homo sapiens GN=EPB41 2 2

EPB41L1 Q9H4G0 >sp|Q9H4G0|E41L1_HUMAN Band 4.1-like protein 1 OS=Homo s 6 7EPB41L2 O43491 >sp|O43491|E41L2_HUMAN Band 4.1-like protein 2 OS=Homo sa 35 83EPB41L3 Q9Y2J2 >sp|Q9Y2J2|E41L3_HUMAN Band 4.1-like protein 3 OS=Homo sa 5 6EPB41L3 Q9Y2J2-2 >sp|Q9Y2J2-2|E41L3_HUMAN Isoform 2 of Band 4.1-like protein 1 1EPDR1 Q9UM22 >sp|Q9UM22|EPDR1_HUMAN Mammalian ependymin-related prot 1 1EPHX1 P07099 >sp|P07099|HYEP_HUMAN Epoxide hydrolase 1 OS=Homo sapie 23 131EPHX2 P34913 >sp|P34913|HYES_HUMAN Bifunctional epoxide hydrolase 2 OS 3 3EPN1 Q9Y6I3 >sp|Q9Y6I3|EPN1_HUMAN Epsin-1 OS=Homo sapiens GN=EPN1 2 2

EPPK1 P58107 >sp|P58107|EPIPL_HUMAN Epiplakin OS=Homo sapiens GN=EPP 2 2EPRS P07814 >sp|P07814|SYEP_HUMAN Bifunctional glutamate/proline--tRNA 1 1EPS15 P42566 >sp|P42566|EPS15_HUMAN Epidermal growth factor receptor su 2 3

EPS15L1 Q9UBC2 >sp|Q9UBC2|EP15R_HUMAN Epidermal growth factor receptor su 1 1ERAP1 Q9NZ08 >sp|Q9NZ08|ERAP1_HUMAN Endoplasmic reticulum aminopeptid 16 35ERGIC1 Q969X5 >sp|Q969X5|ERGI1_HUMAN Endoplasmic reticulum-Golgi interme 3 4

ERH P84090 >sp|P84090|ERH_HUMAN Enhancer of rudimentary homolog OS= 2 3ERLIN1 O75477 >sp|O75477|ERLN1_HUMAN Erlin-1 OS=Homo sapiens GN=ERLIN 4 12ERLIN2 O94905 >sp|O94905|ERLN2_HUMAN Erlin-2 OS=Homo sapiens GN=ERLIN 6 12ERO1L Q96HE7 >sp|Q96HE7|ERO1A_HUMAN ERO1-like protein alpha OS=Homo 3 4ERP29 P30040 >sp|P30040|ERP29_HUMAN Endoplasmic reticulum resident prot 6 12ERP44 Q9BS26 >sp|Q9BS26|ERP44_HUMAN Endoplasmic reticulum resident pro 6 15ESCO2 Q56NI9 >sp|Q56NI9|ESCO2_HUMAN N-acetyltransferase ESCO2 OS=Ho 1 1

ESD P10768 >sp|P10768|ESTD_HUMAN S-formylglutathione hydrolase OS=Ho 8 19ESRRB O95718 >sp|O95718|ERR2_HUMAN Steroid hormone receptor ERR2 OS= 1 1ESYT1 Q9BSJ8 >sp|Q9BSJ8|ESYT1_HUMAN Extended synaptotagmin-1 OS=Homo 19 58ESYT2 A0FGR8 >sp|A0FGR8|ESYT2_HUMAN Extended synaptotagmin-2 OS=Hom 5 9ESYT2 A0FGR8-2 >sp|A0FGR8-2|ESYT2_HUMAN Isoform 2 of Extended synaptotag 1 3ETFA P13804 >sp|P13804|ETFA_HUMAN Electron transfer flavoprotein subunit 9 43ETFB P38117 >sp|P38117|ETFB_HUMAN Electron transfer flavoprotein subuni 7 47

ETFDH Q16134 >sp|Q16134|ETFD_HUMAN Electron transfer flavoprotein-ubiquin 9 18ETS1 P14921 >sp|P14921|ETS1_HUMAN Protein C-ets-1 OS=Homo sapiens GN 1 1

EVA1B Q9NVM1 >sp|Q9NVM1|EVA1B_HUMAN Protein eva-1 homolog B OS=Homo 1 1EXOC8 Q8IYI6 >sp|Q8IYI6|EXOC8_HUMAN Exocyst complex component 8 OS=H 2 3EXT2 Q93063 >sp|Q93063|EXT2_HUMAN Exostosin-2 OS=Homo sapiens GN=E 1 1

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EZR P15311 >sp|P15311|EZRI_HUMAN Ezrin OS=Homo sapiens GN=EZR PE= 23 75F10 P00742 >sp|P00742|FA10_HUMAN Coagulation factor X OS=Homo sapien 1 1

F11R Q9Y624 >sp|Q9Y624|JAM1_HUMAN Junctional adhesion molecule A OS= 5 6F12 P00748 >sp|P00748|FA12_HUMAN Coagulation factor XII OS=Homo sapi 2 2

F13A1 P00488 >sp|P00488|F13A_HUMAN Coagulation factor XIII A chain OS=H 29 102F2 P00734 >sp|P00734|THRB_HUMAN Prothrombin OS=Homo sapiens GN=F 19 63

FABP4 P15090 >sp|P15090|FABP4_HUMAN Fatty acid-binding protein, adipocy 25 1177FABP5 Q01469 >sp|Q01469|FABP5_HUMAN Fatty acid-binding protein, epiderm 19 110FAF2 Q96CS3 >sp|Q96CS3|FAF2_HUMAN FAS-associated factor 2 OS=Homo sa 1 1FAH P16930 >sp|P16930|FAAA_HUMAN Fumarylacetoacetase OS=Homo sapi 12 43

FAHD1 Q6P587 >sp|Q6P587|FAHD1_HUMAN Acylpyruvase FAHD1, mitochondria 3 3FAM114A1 Q8IWE2 >sp|Q8IWE2|NXP20_HUMAN Protein NOXP20 OS=Homo sapiens 1 1FAM134C Q86VR2 >sp|Q86VR2|F134C_HUMAN Protein FAM134C OS=Homo sapien 1 1FAM135B Q49AJ0 >sp|Q49AJ0|F135B_HUMAN Protein FAM135B OS=Homo sapiens 1 1

FAM160B1 Q5W0V3 >sp|Q5W0V3|F16B1_HUMAN Protein FAM160B1 OS=Homo sapie 1 1FAM162A Q96A26 >sp|Q96A26|F162A_HUMAN Protein FAM162A OS=Homo sapien 2 4FAM213A Q9BRX8 >sp|Q9BRX8|F213A_HUMAN Redox-regulatory protein FAM213A 13 82FAM21A Q641Q2 >sp|Q641Q2|FA21A_HUMAN WASH complex subunit FAM21A OS 1 3FAM45A Q8TCE6 >sp|Q8TCE6|FA45A_HUMAN Protein FAM45A OS=Homo sapiens 1 1FAM45A Q8TCE6-2 >sp|Q8TCE6-2|FA45A_HUMAN Isoform 2 of Protein FAM45A OS 1 1FAM49B Q9NUQ9 >sp|Q9NUQ9|FA49B_HUMAN Protein FAM49B OS=Homo sapiens 6 11FAM65A Q6ZS17 >sp|Q6ZS17|FA65A_HUMAN Protein FAM65A OS=Homo sapiens 2 4FAM83B Q5T0W9 >sp|Q5T0W9|FA83B_HUMAN Protein FAM83B OS=Homo sapiens 1 2FARSA Q9Y285 >sp|Q9Y285|SYFA_HUMAN Phenylalanine--tRNA ligase alpha su 1 1FARSB Q9NSD9 >sp|Q9NSD9|SYFB_HUMAN Phenylalanine--tRNA ligase beta su 1 1FASN P49327 >sp|P49327|FAS_HUMAN Fatty acid synthase OS=Homo sapiens 103 520FAU P62861 >sp|P62861|RS30_HUMAN 40S ribosomal protein S30 OS=Homo 1 1

FBLN1 P23142 >sp|P23142|FBLN1_HUMAN Fibulin-1 OS=Homo sapiens GN=FBL 7 11FBLN1 P23142-4 >sp|P23142-4|FBLN1_HUMAN Isoform C of Fibulin-1 OS=Homo s 2 2FBLN2 P98095 >sp|P98095|FBLN2_HUMAN Fibulin-2 OS=Homo sapiens GN=FBL 1 1FBLN5 Q9UBX5 >sp|Q9UBX5|FBLN5_HUMAN Fibulin-5 OS=Homo sapiens GN=FB 2 2FBN1 P35555 >sp|P35555|FBN1_HUMAN Fibrillin-1 OS=Homo sapiens GN=FBN 10 13FBP1 P09467 >sp|P09467|F16P1_HUMAN Fructose-1,6-bisphosphatase 1 OS= 2 10FBP2 O00757 >sp|O00757|F16P2_HUMAN Fructose-1,6-bisphosphatase isozym 1 1

FBXO38 Q6PIJ6-3 >sp|Q6PIJ6-3|FBX38_HUMAN Isoform 3 of F-box only protein 3 1 1FCGRT P55899 >sp|P55899|FCGRN_HUMAN IgG receptor FcRn large subunit p 5 11FCN1 O00602 >sp|O00602|FCN1_HUMAN Ficolin-1 OS=Homo sapiens GN=FCN1 1 2

FCRLB Q6BAA4 >sp|Q6BAA4|FCRLB_HUMAN Fc receptor-like B OS=Homo sapie 1 1FDPS P14324 >sp|P14324|FPPS_HUMAN Farnesyl pyrophosphate synthase OS 2 3

FERMT1 Q9BQL6 >sp|Q9BQL6|FERM1_HUMAN Fermitin family homolog 1 OS=Hom 1 7FERMT2 Q96AC1 >sp|Q96AC1|FERM2_HUMAN Fermitin family homolog 2 OS=Hom 22 64

FGA P02671 >sp|P02671|FIBA_HUMAN Fibrinogen alpha chain OS=Homo sap 34 210FGB P02675 >sp|P02675|FIBB_HUMAN Fibrinogen beta chain OS=Homo sapi 36 258

FGD6 Q6ZV73 >sp|Q6ZV73|FGD6_HUMAN FYVE, RhoGEF and PH domain-contain 1 2FGF2 P09038 >sp|P09038|FGF2_HUMAN Fibroblast growth factor 2 OS=Homo 1 1FGG P02679 >sp|P02679|FIBG_HUMAN Fibrinogen gamma chain OS=Homo sa 28 230FH P07954 >sp|P07954|FUMH_HUMAN Fumarate hydratase, mitochondrial 9 20

FHL1 Q13642 >sp|Q13642|FHL1_HUMAN Four and a half LIM domains protein 13 163FHL1 Q13642-1 >sp|Q13642-1|FHL1_HUMAN Isoform 1 of Four and a half LIM dom 5 46FIS1 Q9Y3D6 >sp|Q9Y3D6|FIS1_HUMAN Mitochondrial fission 1 protein OS=Ho 1 1

FKBP1A P62942 >sp|P62942|FKB1A_HUMAN Peptidyl-prolyl cis-trans isomeras 2 6FKBP2 P26885 >sp|P26885|FKBP2_HUMAN Peptidyl-prolyl cis-trans isomerase 3 10FKBP3 Q00688 >sp|Q00688|FKBP3_HUMAN Peptidyl-prolyl cis-trans isomeras 1 1FKBP4 Q02790 >sp|Q02790|FKBP4_HUMAN Peptidyl-prolyl cis-trans isomeras 2 4FKBP9 O95302 >sp|O95302|FKBP9_HUMAN Peptidyl-prolyl cis-trans isomeras 1 1

FLG L8E7P6 >tr|L8E7P6|L8E7P6_HUMAN Alternative protein FLG OS=Homo s 1 1FLII Q13045 >sp|Q13045|FLII_HUMAN Protein flightless-1 homolog OS=Homo 1 3

FLJ00144 Q8TEP9 >tr|Q8TEP9|Q8TEP9_HUMAN FLJ00144 protein (Fragment) OS=H 1 1FLNA P21333 >sp|P21333|FLNA_HUMAN Filamin-A OS=Homo sapiens GN=FLN 104 462FLNB O75369 >sp|O75369|FLNB_HUMAN Filamin-B OS=Homo sapiens GN=FLN 27 51FLNC Q14315 >sp|Q14315|FLNC_HUMAN Filamin-C OS=Homo sapiens GN=FLN 5 9FLOT1 O75955 >sp|O75955|FLOT1_HUMAN Flotillin-1 OS=Homo sapiens GN=FL 2 3FLOT2 Q14254 >sp|Q14254|FLOT2_HUMAN Flotillin-2 OS=Homo sapiens GN=FL 3 5FMO1 Q01740 >sp|Q01740|FMO1_HUMAN Dimethylaniline monooxygenase [N-ox 1 1

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FMOD Q06828 >sp|Q06828|FMOD_HUMAN Fibromodulin OS=Homo sapiens GN 2 2FN1 P02751 >sp|P02751|FINC_HUMAN Fibronectin OS=Homo sapiens GN=FN 8 9

FN3K Q9H479 >sp|Q9H479|FN3K_HUMAN Fructosamine-3-kinase OS=Homo sap 1 1FN3KRP Q9HA64 >sp|Q9HA64|KT3K_HUMAN Ketosamine-3-kinase OS=Homo sapi 1 1

FNTA P49354 >sp|P49354|FNTA_HUMAN Protein farnesyltransferase/geranylger 1 1FOLR2 P14207 >sp|P14207|FOLR2_HUMAN Folate receptor beta OS=Homo sapi 3 8FSBP O95073 >sp|O95073|FSBP_HUMAN Fibrinogen silencer-binding protein 1 2

FSCN1 Q16658 >sp|Q16658|FSCN1_HUMAN Fascin OS=Homo sapiens GN=FSCN 10 30FSTL1 Q12841 >sp|Q12841|FSTL1_HUMAN Follistatin-related protein 1 OS=Hom 2 3FTH1 P02794 >sp|P02794|FRIH_HUMAN Ferritin heavy chain OS=Homo sapien 7 24FTL P02792 >sp|P02792|FRIL_HUMAN Ferritin light chain OS=Homo sapiens 8 46

FUBP1 Q96AE4 >sp|Q96AE4|FUBP1_HUMAN Far upstream element-binding prote 1 1FUCA1 P04066 >sp|P04066|FUCO_HUMAN Tissue alpha-L-fucosidase OS=Homo 1 2

FYN P06241 >sp|P06241|FYN_HUMAN Tyrosine-protein kinase Fyn OS=Homo 1 2G3BP1 Q13283 >sp|Q13283|G3BP1_HUMAN Ras GTPase-activating protein-bindi 2 3G6PD P11413 >sp|P11413|G6PD_HUMAN Glucose-6-phosphate 1-dehydrogena 11 19GAA P10253 >sp|P10253|LYAG_HUMAN Lysosomal alpha-glucosidase OS=Ho 1 1GALE Q14376 >sp|Q14376|GALE_HUMAN UDP-glucose 4-epimerase OS=Homo 1 1

GALK1 P51570 >sp|P51570|GALK1_HUMAN Galactokinase OS=Homo sapiens G 1 1GALNT5 Q7Z7M9 >sp|Q7Z7M9|GALT5_HUMAN Polypeptide N-acetylgalactosaminyl 1 1GANAB Q14697 >sp|Q14697|GANAB_HUMAN Neutral alpha-glucosidase AB OS= 29 72GANAB Q14697-2 >sp|Q14697-2|GANAB_HUMAN Isoform 2 of Neutral alpha-gluco 1 1GAP43 P17677 >sp|P17677|NEUM_HUMAN Neuromodulin OS=Homo sapiens GN 1 1GAPDH P04406 >sp|P04406|G3P_HUMAN Glyceraldehyde-3-phosphate dehydro 31 380

GAPDHS O14556 >sp|O14556|G3PT_HUMAN Glyceraldehyde-3-phosphate dehydrog 1 2GAREML Q75VX8 >sp|Q75VX8|GAREL_HUMAN GRB2-associated and regulator of 1 1

GARS P41250 >sp|P41250|SYG_HUMAN Glycine--tRNA ligase OS=Homo sapie 2 2GATM P50440 >sp|P50440|GATM_HUMAN Glycine amidinotransferase, mitocho 2 4GBE1 Q04446 >sp|Q04446|GLGB_HUMAN 1,4-alpha-glucan-branching enzyme 11 27

GC D6RF35 >tr|D6RF35|D6RF35_HUMAN Vitamin D-binding protein OS=Homo 2 3GC P02774 >sp|P02774|VTDB_HUMAN Vitamin D-binding protein OS=Homo 28 110

GCA P28676 >sp|P28676|GRAN_HUMAN Grancalcin OS=Homo sapiens GN=GC 1 1GCDH Q92947 >sp|Q92947|GCDH_HUMAN Glutaryl-CoA dehydrogenase, mitoch 1 1GCLC P48506 >sp|P48506|GSH1_HUMAN Glutamate--cysteine ligase catalytic 3 10GCLM P48507 >sp|P48507|GSH0_HUMAN Glutamate--cysteine ligase regulator 1 1GCSH P23434 >sp|P23434|GCSH_HUMAN Glycine cleavage system H protein, m 2 4gdf7 Q75RY1 >tr|Q75RY1|Q75RY1_HUMAN Growth differentiation factor 7 OS= 1 1GDI1 P31150 >sp|P31150|GDIA_HUMAN Rab GDP dissociation inhibitor alpha 15 41GDI2 P50395 >sp|P50395|GDIB_HUMAN Rab GDP dissociation inhibitor beta 13 41GFAP P14136 >sp|P14136|GFAP_HUMAN Glial fibrillary acidic protein OS=Ho 2 9GFER P55789 >sp|P55789|ALR_HUMAN FAD-linked sulfhydryl oxidase ALR OS 1 1GFPT1 Q06210 >sp|Q06210|GFPT1_HUMAN Glutamine--fructose-6-phosphate amin 2 2GGCT O75223 >sp|O75223|GGCT_HUMAN Gamma-glutamylcyclotransferase OS 2 2GGT5 P36269 >sp|P36269|GGT5_HUMAN Gamma-glutamyltransferase 5 OS=Ho 4 4

GIMAP4 Q9NUV9 >sp|Q9NUV9|GIMA4_HUMAN GTPase IMAP family member 4 OS= 5 6GLG1 Q92896 >sp|Q92896|GSLG1_HUMAN Golgi apparatus protein 1 OS=Homo 2 3

GLIPR2 Q9H4G4 >sp|Q9H4G4|GAPR1_HUMAN Golgi-associated plant pathogenesis 3 4GLO1 Q04760 >sp|Q04760|LGUL_HUMAN Lactoylglutathione lyase OS=Homo s 6 20

GLOD4 Q9HC38 >sp|Q9HC38|GLOD4_HUMAN Glyoxalase domain-containing prot 3 5GLOD4 Q9HC38-2 >sp|Q9HC38-2|GLOD4_HUMAN Isoform 2 of Glyoxalase domain-co 1 1GLRX P35754 >sp|P35754|GLRX1_HUMAN Glutaredoxin-1 OS=Homo sapiens 4 17

GLRX3 O76003 >sp|O76003|GLRX3_HUMAN Glutaredoxin-3 OS=Homo sapiens 3 4GLT6D1 Q7Z4J2 >sp|Q7Z4J2|GL6D1_HUMAN Glycosyltransferase 6 domain-contai 1 1GLUD1 P00367 >sp|P00367|DHE3_HUMAN Glutamate dehydrogenase 1, mitocho 20 60GLUL P15104 >sp|P15104|GLNA_HUMAN Glutamine synthetase OS=Homo sapi 3 4

GLYAT Q6IB77 >sp|Q6IB77|GLYAT_HUMAN Glycine N-acyltransferase OS=Homo 2 2GLYR1 Q49A26 >sp|Q49A26|GLYR1_HUMAN Putative oxidoreductase GLYR1 OS 1 1GMFB P60983 >sp|P60983|GMFB_HUMAN Glia maturation factor beta OS=Hom 2 4GMFG O60234 >sp|O60234|GMFG_HUMAN Glia maturation factor gamma OS=H 1 1

GMPR2 Q9P2T1 >sp|Q9P2T1|GMPR2_HUMAN GMP reductase 2 OS=Homo sapie 2 2GNA11 P29992 >sp|P29992|GNA11_HUMAN Guanine nucleotide-binding protein 3 3GNA12 Q03113 >sp|Q03113|GNA12_HUMAN Guanine nucleotide-binding protein 1 5GNA13 Q14344 >sp|Q14344|GNA13_HUMAN Guanine nucleotide-binding protein 2 2GNAI1 P63096 >sp|P63096|GNAI1_HUMAN Guanine nucleotide-binding protein G 16 64

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GNAI2 P04899 >sp|P04899|GNAI2_HUMAN Guanine nucleotide-binding protein G 11 49GNAI3 P08754 >sp|P08754|GNAI3_HUMAN Guanine nucleotide-binding protein G 2 5GNAQ P50148 >sp|P50148|GNAQ_HUMAN Guanine nucleotide-binding protein G 3 5GNAS Q5JWF2 >sp|Q5JWF2|GNAS1_HUMAN Guanine nucleotide-binding protein 11 22GNB1 P62873 >sp|P62873|GBB1_HUMAN Guanine nucleotide-binding protein G( 15 65GNB2 P62879 >sp|P62879|GBB2_HUMAN Guanine nucleotide-binding protein G( 10 46

GNB2L1 P63244 >sp|P63244|GBLP_HUMAN Guanine nucleotide-binding protein su 13 42GNG12 Q9UBI6 >sp|Q9UBI6|GBG12_HUMAN Guanine nucleotide-binding protein 5 19GNG2 P59768 >sp|P59768|GBG2_HUMAN Guanine nucleotide-binding protein G 5 36

GNPDA1 P46926 >sp|P46926|GNPI1_HUMAN Glucosamine-6-phosphate isomeras 3 8GNS P15586 >sp|P15586|GNS_HUMAN N-acetylglucosamine-6-sulfatase OS= 2 2

GOLIM4 O00461 >sp|O00461|GOLI4_HUMAN Golgi integral membrane protein 4 1 1GOT1 P17174 >sp|P17174|AATC_HUMAN Aspartate aminotransferase, cytopla 2 2GOT2 P00505 >sp|P00505|AATM_HUMAN Aspartate aminotransferase, mitocho 2 2GPAM Q9HCL2 >sp|Q9HCL2|GPAT1_HUMAN Glycerol-3-phosphate acyltransferas 6 11

GPATCH2 Q9NW75 >sp|Q9NW75|GPTC2_HUMAN G patch domain-containing protei 1 1GPC4 O75487 >sp|O75487|GPC4_HUMAN Glypican-4 OS=Homo sapiens GN=GP 1 3GPD1 P21695 >sp|P21695|GPDA_HUMAN Glycerol-3-phosphate dehydrogenase 46 481

GPD1L Q8N335 >sp|Q8N335|GPD1L_HUMAN Glycerol-3-phosphate dehydrogenase 5 7GPD2 P43304 >sp|P43304|GPDM_HUMAN Glycerol-3-phosphate dehydrogenase, 4 5GPI P06744 >sp|P06744|G6PI_HUMAN Glucose-6-phosphate isomerase OS=H 27 113

GPS1 Q13098 >sp|Q13098|CSN1_HUMAN COP9 signalosome complex subunit 3 3GPT P24298 >sp|P24298|ALAT1_HUMAN Alanine aminotransferase 1 OS=Hom 4 5

GPX1 P07203 >sp|P07203|GPX1_HUMAN Glutathione peroxidase 1 OS=Homo s 14 55GPX3 P22352 >sp|P22352|GPX3_HUMAN Glutathione peroxidase 3 OS=Homo s 7 15GPX4 P36969 >sp|P36969|GPX4_HUMAN Phospholipid hydroperoxide glutathion 8 23GRB2 P62993 >sp|P62993|GRB2_HUMAN Growth factor receptor-bound protei 1 1

GRHPR Q9UBQ7 >sp|Q9UBQ7|GRHPR_HUMAN Glyoxylate reductase/hydroxypyruv 9 25GRIN2C Q14957 >sp|Q14957|NMDE3_HUMAN Glutamate receptor ionotropic, NM 1 1

gs58 Q96S09 >tr|Q96S09|Q96S09_HUMAN Putative uncharacterized protein g 1 2GSN P06396 >sp|P06396|GELS_HUMAN Gelsolin OS=Homo sapiens GN=GSN 30 118GSR P00390 >sp|P00390|GSHR_HUMAN Glutathione reductase, mitochondria 5 8GSS P48637 >sp|P48637|GSHB_HUMAN Glutathione synthetase OS=Homo sa 3 9

GSTK1 Q9Y2Q3 >sp|Q9Y2Q3|GSTK1_HUMAN Glutathione S-transferase kappa 1 3 9GSTM1 P09488 >sp|P09488|GSTM1_HUMAN Glutathione S-transferase Mu 1 OS 10 23GSTM2 P28161 >sp|P28161|GSTM2_HUMAN Glutathione S-transferase Mu 2 OS 5 20GSTM3 P21266 >sp|P21266|GSTM3_HUMAN Glutathione S-transferase Mu 3 OS 9 19GSTO1 P78417 >sp|P78417|GSTO1_HUMAN Glutathione S-transferase omega-1 8 16GSTP1 C7DJS2 >tr|C7DJS2|C7DJS2_HUMAN Glutathione S-transferase pi (Frag 1 9GSTP1 P09211 >sp|P09211|GSTP1_HUMAN Glutathione S-transferase P OS=Ho 11 122GSTT1 P30711 >sp|P30711|GSTT1_HUMAN Glutathione S-transferase theta-1 3 8GSTT2 P0CG29 >sp|P0CG29|GST2_HUMAN Glutathione S-transferase theta-2 O 1 1GSTZ1 O43708 >sp|O43708|MAAI_HUMAN Maleylacetoacetate isomerase OS=Ho 1 1GUSB P08236 >sp|P08236|BGLR_HUMAN Beta-glucuronidase OS=Homo sapie 1 1GYG1 P46976 >sp|P46976|GLYG_HUMAN Glycogenin-1 OS=Homo sapiens GN= 1 1GYPA P02724 >sp|P02724|GLPA_HUMAN Glycophorin-A OS=Homo sapiens GN 1 2GYPC P04921 >sp|P04921|GLPC_HUMAN Glycophorin-C OS=Homo sapiens GN 1 4GYS1 P13807 >sp|P13807|GYS1_HUMAN Glycogen [starch] synthase, muscle 4 6H1F0 P07305 >sp|P07305|H10_HUMAN Histone H1.0 OS=Homo sapiens GN=H1 3 15H1FX Q92522 >sp|Q92522|H1X_HUMAN Histone H1x OS=Homo sapiens GN=H1 2 6

H2AFV Q71UI9 >sp|Q71UI9|H2AV_HUMAN Histone H2A.V OS=Homo sapiens GN 2 6H2AFY O75367 >sp|O75367|H2AY_HUMAN Core histone macro-H2A.1 OS=Homo 2 4

H2AFY2 Q9P0M6 >sp|Q9P0M6|H2AW_HUMAN Core histone macro-H2A.2 OS=Homo 1 2H6PD O95479 >sp|O95479|G6PE_HUMAN GDH/6PGL endoplasmic bifunctional 5 8HADH Q16836 >sp|Q16836|HCDH_HUMAN Hydroxyacyl-coenzyme A dehydrogena 16 77

HADHA P40939 >sp|P40939|ECHA_HUMAN Trifunctional enzyme subunit alpha, 38 166HADHB P55084 >sp|P55084|ECHB_HUMAN Trifunctional enzyme subunit beta, m 20 64HAGH Q16775 >sp|Q16775|GLO2_HUMAN Hydroxyacylglutathione hydrolase, mi 6 7HARS P12081 >sp|P12081|SYHC_HUMAN Histidine--tRNA ligase, cytoplasmic 2 2HBA1 I1VZV6 >tr|I1VZV6|I1VZV6_HUMAN Hemoglobin alpha 1 OS=Homo sapie 3 4HBA1 P69905 >sp|P69905|HBA_HUMAN Hemoglobin subunit alpha OS=Homo s 13 1755HBA1 Q86YQ4 >tr|Q86YQ4|Q86YQ4_HUMAN Alpha-1 globin (Fragment) OS=Hom 3 7HBA2 Q7Z6G4 >tr|Q7Z6G4|Q7Z6G4_HUMAN HBA2 (Fragment) OS=Homo sapien 1 2HBA2 Q86YQ1 >tr|Q86YQ1|Q86YQ1_HUMAN Hemoglobin alpha-2 (Fragment) O 2 2

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HBA2 U3PXP0 >tr|U3PXP0|U3PXP0_HUMAN Alpha globin chain (Fragment) OS 1 1HBA2 U6A3P2 >tr|U6A3P2|U6A3P2_HUMAN Mutant hemoglobin alpha 2 globin c 1 5HBB E9M263 >tr|E9M263|E9M263_HUMAN Hemoglobin beta chain (Fragment) 2 13HBB E9NGZ5 >tr|E9NGZ5|E9NGZ5_HUMAN Hemoglobin beta globin chain (Fra 1 1HBB P68871 >sp|P68871|HBB_HUMAN Hemoglobin subunit beta OS=Homo sa 19 1780HBB Q3Y9I8 >tr|Q3Y9I8|Q3Y9I8_HUMAN Hemoglobin beta (Fragment) OS=Ho 2 2HBB Q4TZM4 >tr|Q4TZM4|Q4TZM4_HUMAN Hemoglobin beta chain (Fragment) 3 24HBB Q6VFQ6 >tr|Q6VFQ6|Q6VFQ6_HUMAN Hemoglobin beta chain (Fragment) 1 55HBB Q7Z2K5 >tr|Q7Z2K5|Q7Z2K5_HUMAN Beta-globin (Fragment) OS=Homo s 1 4HBB Q8IUL9 >tr|Q8IUL9|Q8IUL9_HUMAN Hemoglobin beta chain variant Hb.Si 2 6HBB Q8IZI0 >tr|Q8IZI0|Q8IZI0_HUMAN Hemoglobin beta chain variant Hb-I_ 1 2HBB Q9BWU5 >tr|Q9BWU5|Q9BWU5_HUMAN Mutant hemoglobin beta chain (Fr 1 1HBD P02042 >sp|P02042|HBD_HUMAN Hemoglobin subunit delta OS=Homo sa 10 213HBD Q4F786 >tr|Q4F786|Q4F786_HUMAN Hemoglobin delta Etolia variant (F 1 1

HBD/HBB Q5XTR9 >tr|Q5XTR9|Q5XTR9_HUMAN Hemoglobin delta-beta fusion prot 1 1HBE1 P02100 >sp|P02100|HBE_HUMAN Hemoglobin subunit epsilon OS=Homo 1 4HBG1 P69891 >sp|P69891|HBG1_HUMAN Hemoglobin subunit gamma-1 OS=Ho 10 48HBG2 P69892 >sp|P69892|HBG2_HUMAN Hemoglobin subunit gamma-2 OS=Ho 1 4HBZ P02008 >sp|P02008|HBAZ_HUMAN Hemoglobin subunit zeta OS=Homo s 1 22

HCLS1 P14317 >sp|P14317|HCLS1_HUMAN Hematopoietic lineage cell-specific 1 1HDGF P51858 >sp|P51858|HDGF_HUMAN Hepatoma-derived growth factor OS 3 6

HDHD2 Q9H0R4 >sp|Q9H0R4|HDHD2_HUMAN Haloacid dehalogenase-like hydrolas 1 2HEBP1 Q9NRV9 >sp|Q9NRV9|HEBP1_HUMAN Heme-binding protein 1 OS=Homo 7 16HEBP2 Q9Y5Z4 >sp|Q9Y5Z4|HEBP2_HUMAN Heme-binding protein 2 OS=Homo s 5 12

HECTD4 Q9Y4D8 >sp|Q9Y4D8|HECD4_HUMAN Probable E3 ubiquitin-protein lig 1 1HEL-213 V9HW34 >tr|V9HW34|V9HW34_HUMAN Epididymis luminal protein 213 OS 1 1

HEPACAM Q14CZ8 >sp|Q14CZ8|HECAM_HUMAN Hepatocyte cell adhesion molecul 1 1HEPH Q9BQS7 >sp|Q9BQS7|HEPH_HUMAN Hephaestin OS=Homo sapiens GN= 1 1

HERC2 O95714 >sp|O95714|HERC2_HUMAN E3 ubiquitin-protein ligase HERC2 1 1HIBADH P31937 >sp|P31937|3HIDH_HUMAN 3-hydroxyisobutyrate dehydrogenase, 7 15HIBCH Q6NVY1 >sp|Q6NVY1|HIBCH_HUMAN 3-hydroxyisobutyryl-CoA hydrolase, 6 8HINT1 P49773 >sp|P49773|HINT1_HUMAN Histidine triad nucleotide-binding pr 3 6HINT2 Q9BX68 >sp|Q9BX68|HINT2_HUMAN Histidine triad nucleotide-binding pro 3 12HINT3 Q9NQE9 >sp|Q9NQE9|HINT3_HUMAN Histidine triad nucleotide-binding p 1 1HIP1 O00291 >sp|O00291|HIP1_HUMAN Huntingtin-interacting protein 1 OS=H 1 1

HIST1H1A Q02539 >sp|Q02539|H11_HUMAN Histone H1.1 OS=Homo sapiens GN=H 4 39HIST1H1B P16401 >sp|P16401|H15_HUMAN Histone H1.5 OS=Homo sapiens GN=HI 1 3HIST1H1C P16403 >sp|P16403|H12_HUMAN Histone H1.2 OS=Homo sapiens GN=HI 4 49

HIST1H2AA Q96QV6 >sp|Q96QV6|H2A1A_HUMAN Histone H2A type 1-A OS=Homo sa 6 31HIST1H2AB P04908 >sp|P04908|H2A1B_HUMAN Histone H2A type 1-B/E OS=Homo s 2 59HIST1H2AD P20671 >sp|P20671|H2A1D_HUMAN Histone H2A type 1-D OS=Homo sap 1 5HIST1H2BA Q96A08 >sp|Q96A08|H2B1A_HUMAN Histone H2B type 1-A OS=Homo sap 3 32HIST1H2BB P33778 >sp|P33778|H2B1B_HUMAN Histone H2B type 1-B OS=Homo sap 10 89HIST1H2BC P62807 >sp|P62807|H2B1C_HUMAN Histone H2B type 1-C/E/F/G/I OS=H 2 16HIST1H4A P62805 >sp|P62805|H4_HUMAN Histone H4 OS=Homo sapiens GN=HIST 12 144

HIST2H3PS2 Q5TEC6 >tr|Q5TEC6|Q5TEC6_HUMAN Histone H3 OS=Homo sapiens GN= 1 4HIST3H3 Q16695 >sp|Q16695|H31T_HUMAN Histone H3.1t OS=Homo sapiens GN= 5 11

HK1 P19367 >sp|P19367|HXK1_HUMAN Hexokinase-1 OS=Homo sapiens GN= 7 12HK2 P52789 >sp|P52789|HXK2_HUMAN Hexokinase-2 OS=Homo sapiens GN= 3 3

HLA-A P01892 >sp|P01892|1A02_HUMAN HLA class I histocompatibility antigen 1 2HLA-A P30443 >sp|P30443|1A01_HUMAN HLA class I histocompatibility antigen 4 14HLA-B P01889 >sp|P01889|1B07_HUMAN HLA class I histocompatibility antigen 1 6HLA-B P30461 >sp|P30461|1B13_HUMAN HLA class I histocompatibility antigen 1 2

HLA-DRA P01903 >sp|P01903|DRA_HUMAN HLA class II histocompatibility antige 5 14HLA-DRB1 P01912 >sp|P01912|2B13_HUMAN HLA class II histocompatibility antig 1 3HLA-DRB1 P04229 >sp|P04229|2B11_HUMAN HLA class II histocompatibility antig 5 9HLA-DRB1 P13761 >sp|P13761|2B17_HUMAN HLA class II histocompatibility antig 1 1HMG20A Q9NP66 >sp|Q9NP66|HM20A_HUMAN High mobility group protein 20A O 1 1HMGB1 P09429 >sp|P09429|HMGB1_HUMAN High mobility group protein B1 OS 6 13

HMGB1P1 B2RPK0 >sp|B2RPK0|HGB1A_HUMAN Putative high mobility group protei 6 22HMGB2 P26583 >sp|P26583|HMGB2_HUMAN High mobility group protein B2 OS 2 2HMGB3 O15347 >sp|O15347|HMGB3_HUMAN High mobility group protein B3 OS 1 1HMGCL P35914 >sp|P35914|HMGCL_HUMAN Hydroxymethylglutaryl-CoA lyase, m 2 3HMGN2 P05204 >sp|P05204|HMGN2_HUMAN Non-histone chromosomal protein 2 2

Page 17: [XLS]media.nature.com · Web viewSupp-Table S2B Supp-Table S2A Gene name UniProt accession Fasta protein description Unique peptides Spectral counts A1BG P04217 >sp|P04217|A1BG_HUMAN

HNMT P50135 >sp|P50135|HNMT_HUMAN Histamine N-methyltransferase OS= 4 12HNRNPA1L2 Q32P51 >sp|Q32P51|RA1L2_HUMAN Heterogeneous nuclear ribonucleopr 4 7HNRNPA2B1 P22626 >sp|P22626|ROA2_HUMAN Heterogeneous nuclear ribonucleopr 7 11

HNRNPA3 P51991 >sp|P51991|ROA3_HUMAN Heterogeneous nuclear ribonucleopr 2 4HNRNPAB Q99729-2 >sp|Q99729-2|ROAA_HUMAN Isoform 2 of Heterogeneous nuclear 1 1HNRNPC P07910 >sp|P07910|HNRPC_HUMAN Heterogeneous nuclear ribonucleop 6 18

HNRNPCL1 O60812 >sp|O60812|HNRCL_HUMAN Heterogeneous nuclear ribonucleopr 2 7HNRNPD Q14103 >sp|Q14103|HNRPD_HUMAN Heterogeneous nuclear ribonucleop 7 12

HNRNPDL O14979 >sp|O14979|HNRDL_HUMAN Heterogeneous nuclear ribonucleopr 3 5HNRNPF P52597 >sp|P52597|HNRPF_HUMAN Heterogeneous nuclear ribonucleop 2 3

HNRNPH1 P31943 >sp|P31943|HNRH1_HUMAN Heterogeneous nuclear ribonucleop 5 10HNRNPK P61978 >sp|P61978|HNRPK_HUMAN Heterogeneous nuclear ribonucleop 8 22HNRNPL P14866 >sp|P14866|HNRPL_HUMAN Heterogeneous nuclear ribonucleop 1 2HNRNPM P52272 >sp|P52272|HNRPM_HUMAN Heterogeneous nuclear ribonucleop 5 10HNRNPU Q00839 >sp|Q00839|HNRPU_HUMAN Heterogeneous nuclear ribonucleop 5 13

HNRNPUL1 Q9BUJ2 >sp|Q9BUJ2|HNRL1_HUMAN Heterogeneous nuclear ribonucleopro 1 1HNRNPUL2 Q1KMD3 >sp|Q1KMD3|HNRL2_HUMAN Heterogeneous nuclear ribonucleopr 2 2

HOOK3 Q86VS8 >sp|Q86VS8|HOOK3_HUMAN Protein Hook homolog 3 OS=Homo 1 1HP P00738 >sp|P00738|HPT_HUMAN Haptoglobin OS=Homo sapiens GN=HP 15 203

HP1BP3 Q5SSJ5 >sp|Q5SSJ5|HP1B3_HUMAN Heterochromatin protein 1-binding p 2 6HPCA P84074 >sp|P84074|HPCA_HUMAN Neuron-specific calcium-binding prot 1 4

HPCAL4 Q9UM19 >sp|Q9UM19|HPCL4_HUMAN Hippocalcin-like protein 4 OS=Hom 1 1HPR P00739 >sp|P00739|HPTR_HUMAN Haptoglobin-related protein OS=Homo 17 163

HPRT1 P00492 >sp|P00492|HPRT_HUMAN Hypoxanthine-guanine phosphoribosyl 1 1HPX P02790 >sp|P02790|HEMO_HUMAN Hemopexin OS=Homo sapiens GN=H 27 315

HRAS P01112 >sp|P01112|RASH_HUMAN GTPase HRas OS=Homo sapiens GN 2 3HRC L8E9Z3 >tr|L8E9Z3|L8E9Z3_HUMAN Alternative protein HRC OS=Homo s 1 1HRG P04196 >sp|P04196|HRG_HUMAN Histidine-rich glycoprotein OS=Homo 5 24

HRSP12 P52758 >sp|P52758|UK114_HUMAN Ribonuclease UK114 OS=Homo sapi 3 8HS1BP3 Q53T59 >sp|Q53T59|H1BP3_HUMAN HCLS1-binding protein 3 OS=Homo 1 1HSBP1 O75506 >sp|O75506|HSBP1_HUMAN Heat shock factor-binding protein 1 3

HSD17B10 Q99714 >sp|Q99714|HCD2_HUMAN 3-hydroxyacyl-CoA dehydrogenase t 8 16HSD17B11 Q8NBQ5 >sp|Q8NBQ5|DHB11_HUMAN Estradiol 17-beta-dehydrogenase 3 6HSD17B12 Q53GQ0 >sp|Q53GQ0|DHB12_HUMAN Estradiol 17-beta-dehydrogenase 5 10HSD17B13 Q7Z5P4 >sp|Q7Z5P4|DHB13_HUMAN 17-beta-hydroxysteroid dehydrogen 1 1HSD17B4 P51659 >sp|P51659|DHB4_HUMAN Peroxisomal multifunctional enzyme 6 7

HSDL2 Q6YN16 >sp|Q6YN16|HSDL2_HUMAN Hydroxysteroid dehydrogenase-like 7 13HSP90AA1 P07900 >sp|P07900|HS90A_HUMAN Heat shock protein HSP 90-alpha O 28 102HSP90AA2 Q14568 >sp|Q14568|HS902_HUMAN Putative heat shock protein HSP 90 2 7

HSP90AA4P Q58FG1 >sp|Q58FG1|HS904_HUMAN Putative heat shock protein HSP 9 2 5HSP90AA5P Q58FG0 >sp|Q58FG0|HS905_HUMAN Putative heat shock protein HSP 9 2 10HSP90AB1 P08238 >sp|P08238|HS90B_HUMAN Heat shock protein HSP 90-beta OS 13 42

HSP90AB2P Q58FF8 >sp|Q58FF8|H90B2_HUMAN Putative heat shock protein HSP 90 7 29HSP90AB3P Q58FF7 >sp|Q58FF7|H90B3_HUMAN Putative heat shock protein HSP 90 9 39HSP90AB4P Q58FF6 >sp|Q58FF6|H90B4_HUMAN Putative heat shock protein HSP 90 1 1

HSP90B1 P14625 >sp|P14625|ENPL_HUMAN Endoplasmin OS=Homo sapiens GN= 28 124HSP90B2P Q58FF3 >sp|Q58FF3|ENPLL_HUMAN Putative endoplasmin-like protein 8 16HSPA12A O43301 >sp|O43301|HS12A_HUMAN Heat shock 70 kDa protein 12A OS 18 52HSPA12B Q96MM6 >sp|Q96MM6|HS12B_HUMAN Heat shock 70 kDa protein 12B OS 3 6HSPA1A P08107 >sp|P08107|HSP71_HUMAN Heat shock 70 kDa protein 1A/1B O 22 142HSPA1L P34931 >sp|P34931|HS71L_HUMAN Heat shock 70 kDa protein 1-like O 14 100HSPA2 P54652 >sp|P54652|HSP72_HUMAN Heat shock-related 70 kDa protein 6 25HSPA4 P34932 >sp|P34932|HSP74_HUMAN Heat shock 70 kDa protein 4 OS=Ho 6 11

HSPA4L O95757 >sp|O95757|HS74L_HUMAN Heat shock 70 kDa protein 4L OS=H 1 2HSPA5 P11021 >sp|P11021|GRP78_HUMAN 78 kDa glucose-regulated protein 35 162HSPA6 P17066 >sp|P17066|HSP76_HUMAN Heat shock 70 kDa protein 6 OS=Ho 1 5HSPA8 P11142 >sp|P11142|HSP7C_HUMAN Heat shock cognate 71 kDa protein 26 147HSPA9 P38646 >sp|P38646|GRP75_HUMAN Stress-70 protein, mitochondrial O 20 68HSPB1 P04792 >sp|P04792|HSPB1_HUMAN Heat shock protein beta-1 OS=Homo 17 136HSPB2 Q16082 >sp|Q16082|HSPB2_HUMAN Heat shock protein beta-2 OS=Homo 1 1HSPB6 O14558 >sp|O14558|HSPB6_HUMAN Heat shock protein beta-6 OS=Homo 8 77HSPB7 Q9UBY9 >sp|Q9UBY9|HSPB7_HUMAN Heat shock protein beta-7 OS=Hom 1 1HSPD1 P10809 >sp|P10809|CH60_HUMAN 60 kDa heat shock protein, mitochond 29 121HSPE1 P61604 >sp|P61604|CH10_HUMAN 10 kDa heat shock protein, mitochond 7 26

Page 18: [XLS]media.nature.com · Web viewSupp-Table S2B Supp-Table S2A Gene name UniProt accession Fasta protein description Unique peptides Spectral counts A1BG P04217 >sp|P04217|A1BG_HUMAN

HSPG2 P98160 >sp|P98160|PGBM_HUMAN Basement membrane-specific heparan s 27 49HSPH1 Q92598 >sp|Q92598|HS105_HUMAN Heat shock protein 105 kDa OS=Ho 1 3

HuVH8B VH A2NYQ9 >tr|A2NYQ9|A2NYQ9_HUMAN Anti-folate binding protein (Frag 1 2HUWE1 Q7Z6Z7 >sp|Q7Z6Z7|HUWE1_HUMAN E3 ubiquitin-protein ligase HUWE 2 2HVCN1 Q96D96 >sp|Q96D96|HVCN1_HUMAN Voltage-gated hydrogen channel 1 1 1HYAL4 Q2M3T9 >sp|Q2M3T9|HYAL4_HUMAN Hyaluronidase-4 OS=Homo sapiens 1 1HYDIN Q4G0P3 >sp|Q4G0P3|HYDIN_HUMAN Hydrocephalus-inducing protein ho 1 1

HYI Q5T013 >sp|Q5T013|HYI_HUMAN Putative hydroxypyruvate isomerase O 2 5HYOU1 Q9Y4L1 >sp|Q9Y4L1|HYOU1_HUMAN Hypoxia up-regulated protein 1 OS 6 10

IAH1 Q2TAA2 >sp|Q2TAA2|IAH1_HUMAN Isoamyl acetate-hydrolyzing esterase 5 6IARS2 Q9NSE4 >sp|Q9NSE4|SYIM_HUMAN Isoleucine--tRNA ligase, mitochondri 3 3ICAM1 P05362 >sp|P05362|ICAM1_HUMAN Intercellular adhesion molecule 1 O 1 3IDH1 O75874 >sp|O75874|IDHC_HUMAN Isocitrate dehydrogenase [NADP] cyt 27 114IDH2 P48735 >sp|P48735|IDHP_HUMAN Isocitrate dehydrogenase [NADP], mit 14 22

IDH3A P50213 >sp|P50213|IDH3A_HUMAN Isocitrate dehydrogenase [NAD] subun 7 13IDH3B O43837 >sp|O43837|IDH3B_HUMAN Isocitrate dehydrogenase [NAD] subun 2 2IDH3G P51553 >sp|P51553|IDH3G_HUMAN Isocitrate dehydrogenase [NAD] subu 1 1IFI16 Q16666 >sp|Q16666|IF16_HUMAN Gamma-interferon-inducible protein 16 1 1

IGF2R P11717 >sp|P11717|MPRI_HUMAN Cation-independent mannose-6-phosph 2 2IGFBP7 Q16270 >sp|Q16270|IBP7_HUMAN Insulin-like growth factor-binding pro 1 1IGH@ Q6GMX6 >tr|Q6GMX6|Q6GMX6_HUMAN IGH@ protein OS=Homo sapiens 2 8IGHA1 P01876 >sp|P01876|IGHA1_HUMAN Ig alpha-1 chain C region OS=Homo 15 276IGHA2 P01877 >sp|P01877|IGHA2_HUMAN Ig alpha-2 chain C region OS=Homo 1 4IGHD P01880 >sp|P01880|IGHD_HUMAN Ig delta chain C region OS=Homo sap 2 3

IGHG1 P01857 >sp|P01857|IGHG1_HUMAN Ig gamma-1 chain C region OS=Homo 19 653IGHG2 P01859 >sp|P01859|IGHG2_HUMAN Ig gamma-2 chain C region OS=Homo 14 372IGHG3 P01860 >sp|P01860|IGHG3_HUMAN Ig gamma-3 chain C region OS=Homo 6 69IGHG4 P01861 >sp|P01861|IGHG4_HUMAN Ig gamma-4 chain C region OS=Homo 9 51IGHM P01871 >sp|P01871|IGHM_HUMAN Ig mu chain C region OS=Homo sapie 19 122

IGHV4OR15-8 A6NJ16 >sp|A6NJ16|IV4F8_HUMAN Putative V-set and immunoglobulin do 1 3IGJ P01591 >sp|P01591|IGJ_HUMAN Immunoglobulin J chain OS=Homo sapie 3 8

IGK@ Q6PJF2 >tr|Q6PJF2|Q6PJF2_HUMAN IGK@ protein OS=Homo sapiens G 1 17IGKC P01834 >sp|P01834|IGKC_HUMAN Ig kappa chain C region OS=Homo sa 7 597

IGKV4-1 P06312 >sp|P06312|KV401_HUMAN Ig kappa chain V-IV region (Fragmen 3 8IGL@ Q8N355 >tr|Q8N355|Q8N355_HUMAN IGL@ protein OS=Homo sapiens G 1 16IGLC2 P0CG05 >sp|P0CG05|LAC2_HUMAN Ig lambda-2 chain C regions OS=Hom 3 122IGLC7 A0M8Q6 >sp|A0M8Q6|LAC7_HUMAN Ig lambda-7 chain C region OS=Homo 1 2IGLL1 P15814 >sp|P15814|IGLL1_HUMAN Immunoglobulin lambda-like polypept 2 5IGLL5 B9A064 >sp|B9A064|IGLL5_HUMAN Immunoglobulin lambda-like polypept 7 109ILF2 Q12905 >sp|Q12905|ILF2_HUMAN Interleukin enhancer-binding factor 2 2 2ILF3 Q12906 >sp|Q12906|ILF3_HUMAN Interleukin enhancer-binding factor 3 3 3ILK Q13418 >sp|Q13418|ILK_HUMAN Integrin-linked protein kinase OS=Homo 21 60

ILVBL A1L0T0 >sp|A1L0T0|ILVBL_HUMAN Acetolactate synthase-like protein O 3 4IMMP2L Q96T52 >sp|Q96T52|IMP2L_HUMAN Mitochondrial inner membrane protea 2 2

IMMT Q16891 >sp|Q16891|IMMT_HUMAN Mitochondrial inner membrane protei 11 28IMPA1 P29218 >sp|P29218|IMPA1_HUMAN Inositol monophosphatase 1 OS=Hom 1 2

IMPAD1 Q9NX62 >sp|Q9NX62|IMPA3_HUMAN Inositol monophosphatase 3 OS=Ho 1 1IMPDH2 P12268 >sp|P12268|IMDH2_HUMAN Inosine-5'-monophosphate dehydrog 1 3

INA Q16352 >sp|Q16352|AINX_HUMAN Alpha-internexin OS=Homo sapiens G 1 26INF2 Q27J81 >sp|Q27J81|INF2_HUMAN Inverted formin-2 OS=Homo sapiens G 3 3IPO5 O00410 >sp|O00410|IPO5_HUMAN Importin-5 OS=Homo sapiens GN=IPO 4 4IPO7 O95373 >sp|O95373|IPO7_HUMAN Importin-7 OS=Homo sapiens GN=IPO 3 4IPO9 Q96P70 >sp|Q96P70|IPO9_HUMAN Importin-9 OS=Homo sapiens GN=IPO 1 1

IQGAP1 P46940 >sp|P46940|IQGA1_HUMAN Ras GTPase-activating-like protein 41 94IQGAP2 Q13576 >sp|Q13576|IQGA2_HUMAN Ras GTPase-activating-like protein 1 1ISOC1 Q96CN7 >sp|Q96CN7|ISOC1_HUMAN Isochorismatase domain-containing 3 10ISOC2 Q96AB3 >sp|Q96AB3|ISOC2_HUMAN Isochorismatase domain-containing pr 3 4IST1 P53990 >sp|P53990|IST1_HUMAN IST1 homolog OS=Homo sapiens GN=I 1 1

ISYNA1 Q9NPH2 >sp|Q9NPH2|INO1_HUMAN Inositol-3-phosphate synthase 1 OS= 2 3ITFG2 Q969R8 >sp|Q969R8|ITFG2_HUMAN Integrin-alpha FG-GAP repeat-contain 1 1ITGA1 P56199 >sp|P56199|ITA1_HUMAN Integrin alpha-1 OS=Homo sapiens GN 6 9

ITGA2B P08514 >sp|P08514|ITA2B_HUMAN Integrin alpha-IIb OS=Homo sapiens 1 1ITGA6 P23229-2 >sp|P23229-2|ITA6_HUMAN Isoform Alpha-6X1A of Integrin alph 4 4ITGA7 Q13683 >sp|Q13683|ITA7_HUMAN Integrin alpha-7 OS=Homo sapiens GN 15 38

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ITGA7 Q13683-3 >sp|Q13683-3|ITA7_HUMAN Isoform Alpha-7X1B of Integrin alph 1 3ITGAM P11215 >sp|P11215|ITAM_HUMAN Integrin alpha-M OS=Homo sapiens G 1 1ITGAV P06756 >sp|P06756|ITAV_HUMAN Integrin alpha-V OS=Homo sapiens G 3 4ITGB1 P05556 >sp|P05556|ITB1_HUMAN Integrin beta-1 OS=Homo sapiens GN= 23 108ITGB2 D3DSM0 >tr|D3DSM0|D3DSM0_HUMAN Integrin beta OS=Homo sapiens G 1 1ITGB2 P05107 >sp|P05107|ITB2_HUMAN Integrin beta-2 OS=Homo sapiens GN= 1 1ITGB5 P18084 >sp|P18084|ITB5_HUMAN Integrin beta-5 OS=Homo sapiens GN= 1 1ITIH1 P19827 >sp|P19827|ITIH1_HUMAN Inter-alpha-trypsin inhibitor heavy ch 8 31ITIH2 D3DRR6 >tr|D3DRR6|D3DRR6_HUMAN Inter-alpha (Globulin) inhibitor H2 1 1ITIH2 P19823 >sp|P19823|ITIH2_HUMAN Inter-alpha-trypsin inhibitor heavy ch 9 21ITIH3 Q06033 >sp|Q06033|ITIH3_HUMAN Inter-alpha-trypsin inhibitor heavy ch 1 1ITIH4 Q14624 >sp|Q14624|ITIH4_HUMAN Inter-alpha-trypsin inhibitor heavy ch 17 57ITIH5 Q86UX2 >sp|Q86UX2|ITIH5_HUMAN Inter-alpha-trypsin inhibitor heavy c 1 1ITLN1 Q8WWA0 >sp|Q8WWA0|ITLN1_HUMAN Intelectin-1 OS=Homo sapiens GN= 3 6ITPK1 Q13572 >sp|Q13572|ITPK1_HUMAN Inositol-tetrakisphosphate 1-kinase 1 1ITPR2 F5GYT5 >tr|F5GYT5|F5GYT5_HUMAN Inositol 1,4,5-trisphosphate recept 1 1

IVD P26440 >sp|P26440|IVD_HUMAN Isovaleryl-CoA dehydrogenase, mitocho 2 3JAGN1 Q8N5M9 >sp|Q8N5M9|JAGN1_HUMAN Protein jagunal homolog 1 OS=Hom 1 1JARID2 Q92833 >sp|Q92833|JARD2_HUMAN Protein Jumonji OS=Homo sapiens 1 1KANK1 Q14678 >sp|Q14678|KANK1_HUMAN KN motif and ankyrin repeat domain- 1 2KANK2 Q63ZY3 >sp|Q63ZY3|KANK2_HUMAN KN motif and ankyrin repeat domain- 6 6KARS Q15046 >sp|Q15046|SYK_HUMAN Lysine--tRNA ligase OS=Homo sapien 4 4

KATNAL2 Q8IYT4 >sp|Q8IYT4|KATL2_HUMAN Katanin p60 ATPase-containing subun 1 3KAZN Q674X7 >sp|Q674X7|KAZRN_HUMAN Kazrin OS=Homo sapiens GN=KAZN 1 1

KCTD12 Q96CX2 >sp|Q96CX2|KCD12_HUMAN BTB/POZ domain-containing protei 9 20KDM3A Q9Y4C1 >sp|Q9Y4C1|KDM3A_HUMAN Lysine-specific demethylase 3A O 1 1KDM4B K7EQ54 >tr|K7EQ54|K7EQ54_HUMAN Lysine-specific demethylase 4B (F 1 1KDM6A O15550 >sp|O15550|KDM6A_HUMAN Lysine-specific demethylase 6A O 1 1KDM6B O15054 >sp|O15054|KDM6B_HUMAN Lysine-specific demethylase 6B O 1 1KDSR Q06136 >sp|Q06136|KDSR_HUMAN 3-ketodihydrosphingosine reductase 1 2

KHNYN O15037 >sp|O15037|KHNYN_HUMAN Protein KHNYN OS=Homo sapiens 1 1KHSRP Q92945 >sp|Q92945|FUBP2_HUMAN Far upstream element-binding prote 1 1

KIAA1033 Q2M389 >sp|Q2M389|WASH7_HUMAN WASH complex subunit 7 OS=Homo 1 1KIAA1324L A8MWY0 >sp|A8MWY0|K132L_HUMAN UPF0577 protein KIAA1324-like OS 1 1KIAA1881 A8E631 >tr|A8E631|A8E631_HUMAN KIAA1881 protein (Fragment) OS=H 3 27

KIF19 Q2TAC6 >sp|Q2TAC6|KIF19_HUMAN Kinesin-like protein KIF19 OS=Homo 1 2KIF1B O60333-3 >sp|O60333-3|KIF1B_HUMAN Isoform 3 of Kinesin-like protein K 1 1

KIF1Bbeta Q4R9M9 >tr|Q4R9M9|Q4R9M9_HUMAN Kinesin family member 1Bbeta isof 1 1KIF5A Q12840 >sp|Q12840|KIF5A_HUMAN Kinesin heavy chain isoform 5A OS= 2 3KIF5B P33176 >sp|P33176|KINH_HUMAN Kinesin-1 heavy chain OS=Homo sapi 5 9KLC1 Q07866 >sp|Q07866|KLC1_HUMAN Kinesin light chain 1 OS=Homo sapie 1 1

KLKB1 P03952 >sp|P03952|KLKB1_HUMAN Plasma kallikrein OS=Homo sapiens 1 1KMT2B Q9UMN6 >sp|Q9UMN6|KMT2B_HUMAN Histone-lysine N-methyltransferas 1 1KNG1 P01042 >sp|P01042|KNG1_HUMAN Kininogen-1 OS=Homo sapiens GN=K 17 57KNG1 P01042-2 >sp|P01042-2|KNG1_HUMAN Isoform LMW of Kininogen-1 OS=H 2 12

KPNA4 O00629 >sp|O00629|IMA3_HUMAN Importin subunit alpha-3 OS=Homo s 3 4KPNB1 Q14974 >sp|Q14974|IMB1_HUMAN Importin subunit beta-1 OS=Homo sa 14 23KRT1 P04264 >sp|P04264|K2C1_HUMAN Keratin, type II cytoskeletal 1 OS=Ho 16 49

KRT10 P13645 >sp|P13645|K1C10_HUMAN Keratin, type I cytoskeletal 10 OS= 18 38KRT13 P13646 >sp|P13646|K1C13_HUMAN Keratin, type I cytoskeletal 13 OS= 2 5KRT14 P02533 >sp|P02533|K1C14_HUMAN Keratin, type I cytoskeletal 14 OS= 3 11KRT17 Q04695 >sp|Q04695|K1C17_HUMAN Keratin, type I cytoskeletal 17 OS= 1 3KRT18 P05783 >sp|P05783|K1C18_HUMAN Keratin, type I cytoskeletal 18 OS= 7 23KRT19 P08727 >sp|P08727|K1C19_HUMAN Keratin, type I cytoskeletal 19 OS= 11 30KRT2 P35908 >sp|P35908|K22E_HUMAN Keratin, type II cytoskeletal 2 epide 7 18

KRT6A P02538 >sp|P02538|K2C6A_HUMAN Keratin, type II cytoskeletal 6A OS 4 10KRT7 P08729 >sp|P08729|K2C7_HUMAN Keratin, type II cytoskeletal 7 OS=Ho 6 8

KRT73 Q86Y46 >sp|Q86Y46|K2C73_HUMAN Keratin, type II cytoskeletal 73 OS 1 1KRT76 Q01546 >sp|Q01546|K22O_HUMAN Keratin, type II cytoskeletal 2 oral 1 1KRT8 P05787 >sp|P05787|K2C8_HUMAN Keratin, type II cytoskeletal 8 OS=Ho 9 52KRT9 P35527 >sp|P35527|K1C9_HUMAN Keratin, type I cytoskeletal 9 OS=Ho 6 11KTN1 Q86UP2 >sp|Q86UP2|KTN1_HUMAN Kinectin OS=Homo sapiens GN=KTN1 10 12

LAGE3 Q14657 >sp|Q14657|LAGE3_HUMAN EKC/KEOPS complex subunit LAGE 1 1LAMA4 H0UI49 >tr|H0UI49|H0UI49_HUMAN Laminin, alpha 4, isoform CRA_b O 2 13

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LAMA4 Q16363 >sp|Q16363|LAMA4_HUMAN Laminin subunit alpha-4 OS=Homo 45 153LAMB1 P07942 >sp|P07942|LAMB1_HUMAN Laminin subunit beta-1 OS=Homo s 36 122LAMB2 P55268 >sp|P55268|LAMB2_HUMAN Laminin subunit beta-2 OS=Homo s 40 107LAMC1 P11047 >sp|P11047|LAMC1_HUMAN Laminin subunit gamma-1 OS=Homo 47 167LAMC2 Q13753 >sp|Q13753|LAMC2_HUMAN Laminin subunit gamma-2 OS=Homo 1 2LAMP1 P11279 >sp|P11279|LAMP1_HUMAN Lysosome-associated membrane glyc 4 11LAMP2 P13473 >sp|P13473|LAMP2_HUMAN Lysosome-associated membrane glyc 2 3

LAMTOR1 Q6IAA8 >sp|Q6IAA8|LTOR1_HUMAN Ragulator complex protein LAMTO 1 2LAMTOR3 Q9UHA4 >sp|Q9UHA4|LTOR3_HUMAN Ragulator complex protein LAMTO 1 2LANCL1 O43813 >sp|O43813|LANC1_HUMAN LanC-like protein 1 OS=Homo sapie 3 4

LAP3 P28838 >sp|P28838|AMPL_HUMAN Cytosol aminopeptidase OS=Homo sa 20 71LARP1 Q6PKG0 >sp|Q6PKG0|LARP1_HUMAN La-related protein 1 OS=Homo sapi 1 1LARS Q9P2J5 >sp|Q9P2J5|SYLC_HUMAN Leucine--tRNA ligase, cytoplasmic O 1 1LASP1 Q14847 >sp|Q14847|LASP1_HUMAN LIM and SH3 domain protein 1 OS=H 10 22

LBP P18428 >sp|P18428|LBP_HUMAN Lipopolysaccharide-binding protein OS 2 3LCN2 P80188 >sp|P80188|NGAL_HUMAN Neutrophil gelatinase-associated lip 2 2LCP1 P13796 >sp|P13796|PLSL_HUMAN Plastin-2 OS=Homo sapiens GN=LCP1 19 68LDHA P00338 >sp|P00338|LDHA_HUMAN L-lactate dehydrogenase A chain OS 23 153

LDHAL6A Q6ZMR3 >sp|Q6ZMR3|LDH6A_HUMAN L-lactate dehydrogenase A-like 6A 1 4LDHB P07195 >sp|P07195|LDHB_HUMAN L-lactate dehydrogenase B chain OS 21 182LETM1 O95202 >sp|O95202|LETM1_HUMAN LETM1 and EF-hand domain-containing 4 5

LGALS1 P09382 >sp|P09382|LEG1_HUMAN Galectin-1 OS=Homo sapiens GN=LG 10 106LGALS3 P17931 >sp|P17931|LEG3_HUMAN Galectin-3 OS=Homo sapiens GN=LG 6 19

LGALS3BP Q08380 >sp|Q08380|LG3BP_HUMAN Galectin-3-binding protein OS=Hom 7 18LGMN Q99538 >sp|Q99538|LGMN_HUMAN Legumain OS=Homo sapiens GN=LG 1 2LHPP Q9H008 >sp|Q9H008|LHPP_HUMAN Phospholysine phosphohistidine inorg 2 2

LILRB5 O75023 >sp|O75023|LIRB5_HUMAN Leukocyte immunoglobulin-like recep 1 1LIMA1 Q9UHB6 >sp|Q9UHB6|LIMA1_HUMAN LIM domain and actin-binding prote 3 6

LIMCH1 Q9UPQ0 >sp|Q9UPQ0|LIMC1_HUMAN LIM and calponin homology domains- 3 5LIMK2 P53671 >sp|P53671|LIMK2_HUMAN LIM domain kinase 2 OS=Homo sapie 1 1LIMS1 P48059 >sp|P48059|LIMS1_HUMAN LIM and senescent cell antigen-like-c 9 28LIPE Q05469 >sp|Q05469|LIPS_HUMAN Hormone-sensitive lipase OS=Homo sa 37 184

LMAN1 P49257 >sp|P49257|LMAN1_HUMAN Protein ERGIC-53 OS=Homo sapien 3 3LMAN2 Q12907 >sp|Q12907|LMAN2_HUMAN Vesicular integral-membrane protei 5 6LMCD1 Q9NZU5 >sp|Q9NZU5|LMCD1_HUMAN LIM and cysteine-rich domains pro 2 3LMNA P02545 >sp|P02545|LMNA_HUMAN Prelamin-A/C OS=Homo sapiens GN= 41 235LMNB1 P20700 >sp|P20700|LMNB1_HUMAN Lamin-B1 OS=Homo sapiens GN=LM 6 9LMNB2 Q03252 >sp|Q03252|LMNB2_HUMAN Lamin-B2 OS=Homo sapiens GN=LM 11 20

LNP Q9C0E8 >sp|Q9C0E8|LNP_HUMAN Protein lunapark OS=Homo sapiens G 4 4LNPEP Q9UIQ6 >sp|Q9UIQ6|LCAP_HUMAN Leucyl-cystinyl aminopeptidase OS= 1 1LONP1 P36776 >sp|P36776|LONM_HUMAN Lon protease homolog, mitochondria 3 8LPAR1 Q92633 >sp|Q92633|LPAR1_HUMAN Lysophosphatidic acid receptor 1 O 1 1

LPL P06858 >sp|P06858|LIPL_HUMAN Lipoprotein lipase OS=Homo sapiens 1 1LPP Q93052 >sp|Q93052|LPP_HUMAN Lipoma-preferred partner OS=Homo sa 2 4

LRG1 P02750 >sp|P02750|A2GL_HUMAN Leucine-rich alpha-2-glycoprotein O 7 27LRMP Q12912 >sp|Q12912|LRMP_HUMAN Lymphoid-restricted membrane prote 1 13LRP1 Q07954 >sp|Q07954|LRP1_HUMAN Prolow-density lipoprotein receptor-re 32 49

LRPAP1 P30533 >sp|P30533|AMRP_HUMAN Alpha-2-macroglobulin receptor-assoc 2 4LRPPRC P42704 >sp|P42704|LPPRC_HUMAN Leucine-rich PPR motif-containing pr 8 14LRRC39 Q96DD0 >sp|Q96DD0|LRC39_HUMAN Leucine-rich repeat-containing prot 1 5LRRC47 Q8N1G4 >sp|Q8N1G4|LRC47_HUMAN Leucine-rich repeat-containing prot 4 5LRRC59 Q96AG4 >sp|Q96AG4|LRC59_HUMAN Leucine-rich repeat-containing prot 2 3LRRFIP1 Q32MZ4 >sp|Q32MZ4|LRRF1_HUMAN Leucine-rich repeat flightless-intera 1 1LRRN4 Q8WUT4 >sp|Q8WUT4|LRRN4_HUMAN Leucine-rich repeat neuronal prote 1 1LSM2 Q9Y333 >sp|Q9Y333|LSM2_HUMAN U6 snRNA-associated Sm-like protei 2 4LSM3 P62310 >sp|P62310|LSM3_HUMAN U6 snRNA-associated Sm-like protei 1 1LSP1 P33241 >sp|P33241|LSP1_HUMAN Lymphocyte-specific protein 1 OS=Ho 1 1LSS P48449 >sp|P48449|ERG7_HUMAN Lanosterol synthase OS=Homo sapie 2 4

LTA4H P09960 >sp|P09960|LKHA4_HUMAN Leukotriene A-4 hydrolase OS=Homo 9 22LTF P02788 >sp|P02788|TRFL_HUMAN Lactotransferrin OS=Homo sapiens G 12 21

LTN1 O94822 >sp|O94822|LTN1_HUMAN E3 ubiquitin-protein ligase listerin O 1 8LUM P51884 >sp|P51884|LUM_HUMAN Lumican OS=Homo sapiens GN=LUM P 15 267LXN Q9BS40 >sp|Q9BS40|LXN_HUMAN Latexin OS=Homo sapiens GN=LXN PE 3 7

LYPLA1 O75608 >sp|O75608|LYPA1_HUMAN Acyl-protein thioesterase 1 OS=Hom 1 1

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LYVE1 Q9Y5Y7 >sp|Q9Y5Y7|LYVE1_HUMAN Lymphatic vessel endothelial hyaluro 2 3LYZ P61626 >sp|P61626|LYSC_HUMAN Lysozyme C OS=Homo sapiens GN=L 3 4LZIC Q8WZA0 >sp|Q8WZA0|LZIC_HUMAN Protein LZIC OS=Homo sapiens GN=L 1 1M6PR P20645 >sp|P20645|MPRD_HUMAN Cation-dependent mannose-6-phospha 3 7

MAGEA13P A6NCF6 >sp|A6NCF6|MA13P_HUMAN Putative MAGE domain-containing 1 1MAL2 Q969L2 >sp|Q969L2|MAL2_HUMAN Protein MAL2 OS=Homo sapiens GN= 1 9

MAMDC4 Q6UXC1 >sp|Q6UXC1|AEGP_HUMAN Apical endosomal glycoprotein OS= 1 1MAOA P21397 >sp|P21397|AOFA_HUMAN Amine oxidase [flavin-containing] A 16 94MAOB P27338 >sp|P27338|AOFB_HUMAN Amine oxidase [flavin-containing] B 11 29MAP1B P46821 >sp|P46821|MAP1B_HUMAN Microtubule-associated protein 1B 5 6MAP2 P11137 >sp|P11137|MTAP2_HUMAN Microtubule-associated protein 2 O 1 1

MAP2K1 Q02750 >sp|Q02750|MP2K1_HUMAN Dual specificity mitogen-activated p 2 2MAP4 P27816 >sp|P27816|MAP4_HUMAN Microtubule-associated protein 4 OS 29 69MAP4 P27816-5 >sp|P27816-5|MAP4_HUMAN Isoform 5 of Microtubule-associated 1 1

MAP7D1 Q3KQU3 >sp|Q3KQU3|MA7D1_HUMAN MAP7 domain-containing protein 1 1 1MAP7D2 Q96T17 >sp|Q96T17|MA7D2_HUMAN MAP7 domain-containing protein 2 1 1MAPK1 P28482 >sp|P28482|MK01_HUMAN Mitogen-activated protein kinase 1 3 10MAPK3 P27361 >sp|P27361|MK03_HUMAN Mitogen-activated protein kinase 3 6 11

MAPRE1 Q15691 >sp|Q15691|MARE1_HUMAN Microtubule-associated protein RP/ 6 10MAPT P10636 >sp|P10636|TAU_HUMAN Microtubule-associated protein tau O 2 2

MARC1 Q5VT66 >sp|Q5VT66|MARC1_HUMAN Mitochondrial amidoxime-reducing 4 14MARC2 Q969Z3 >sp|Q969Z3|MARC2_HUMAN Mitochondrial amidoxime reducing 5 9

MARCKS P29966 >sp|P29966|MARCS_HUMAN Myristoylated alanine-rich C-kinas 6 16MARCKSL1 P49006 >sp|P49006|MRP_HUMAN MARCKS-related protein OS=Homo sa 2 4

MAST4 H7C2A9 >tr|H7C2A9|H7C2A9_HUMAN Microtubule-associated serine/threo 1 1MAT2A P31153 >sp|P31153|METK2_HUMAN S-adenosylmethionine synthase isof 2 2MAT2B Q9NZL9 >sp|Q9NZL9|MAT2B_HUMAN Methionine adenosyltransferase 2 s 1 1MATR3 P43243 >sp|P43243|MATR3_HUMAN Matrin-3 OS=Homo sapiens GN=MA 3 5MAVS Q7Z434 >sp|Q7Z434|MAVS_HUMAN Mitochondrial antiviral-signaling pro 1 2

MBOAT1 Q6ZNC8 >sp|Q6ZNC8|MBOA1_HUMAN Lysophospholipid acyltransferase 1 5MCAM P43121 >sp|P43121|MUC18_HUMAN Cell surface glycoprotein MUC18 26 117MCCC2 Q9HCC0 >sp|Q9HCC0|MCCB_HUMAN Methylcrotonoyl-CoA carboxylase bet 2 4MCMBP Q9BTE3 >sp|Q9BTE3|MCMBP_HUMAN Mini-chromosome maintenance comp 1 1MDH1 P40925 >sp|P40925|MDHC_HUMAN Malate dehydrogenase, cytoplasmic 19 143MDH2 P40926 >sp|P40926|MDHM_HUMAN Malate dehydrogenase, mitochondria 17 90ME1 P48163 >sp|P48163|MAOX_HUMAN NADP-dependent malic enzyme OS=H 13 26

MECR Q9BV79 >sp|Q9BV79|MECR_HUMAN Trans-2-enoyl-CoA reductase, mitoc 1 1MED14 O60244 >sp|O60244|MED14_HUMAN Mediator of RNA polymerase II trans 1 1MEST Q5EB52 >sp|Q5EB52|MEST_HUMAN Mesoderm-specific transcript homolo 2 2

METAP2 P50579 >sp|P50579|MAP2_HUMAN Methionine aminopeptidase 2 OS=Ho 1 1METTL7A Q9H8H3 >sp|Q9H8H3|MET7A_HUMAN Methyltransferase-like protein 7A 6 20

MFAP4 P55083 >sp|P55083|MFAP4_HUMAN Microfibril-associated glycoprotein 5 11MFAP5 Q13361 >sp|Q13361|MFAP5_HUMAN Microfibrillar-associated protein 5 1 1MFN2 O95140 >sp|O95140|MFN2_HUMAN Mitofusin-2 OS=Homo sapiens GN=M 1 1

MFSD10 Q14728 >sp|Q14728|MFS10_HUMAN Major facilitator superfamily domain 1 3MGLL Q99685 >sp|Q99685|MGLL_HUMAN Monoglyceride lipase OS=Homo sapi 7 25MGMT P16455 >sp|P16455|MGMT_HUMAN Methylated-DNA--protein-cysteine me 2 2MGST1 P10620 >sp|P10620|MGST1_HUMAN Microsomal glutathione S-transfera 10 58MGST3 O14880 >sp|O14880|MGST3_HUMAN Microsomal glutathione S-transfera 7 20MICAL1 Q8TDZ2 >sp|Q8TDZ2|MICA1_HUMAN Protein-methionine sulfoxide oxida 1 1MICU2 Q8IYU8 >sp|Q8IYU8|MICU2_HUMAN Calcium uptake protein 2, mitochond 1 1

MIF P14174 >sp|P14174|MIF_HUMAN Macrophage migration inhibitory factor 2 7MKKS Q9HB66 >tr|Q9HB66|Q9HB66_HUMAN Alternative protein MKKS OS=Hom 1 1MLEC Q14165 >sp|Q14165|MLEC_HUMAN Malectin OS=Homo sapiens GN=MLE 5 11MMAB Q96EY8 >sp|Q96EY8|MMAB_HUMAN Cob(I)yrinic acid a,c-diamide adenosy 1 2MMP9 P14780 >sp|P14780|MMP9_HUMAN Matrix metalloproteinase-9 OS=Homo 1 1MOGS Q13724 >sp|Q13724|MOGS_HUMAN Mannosyl-oligosaccharide glucosid 1 1

MORF4L2 Q15014 >sp|Q15014|MO4L2_HUMAN Mortality factor 4-like protein 2 O 1 1MOV10 Q9HCE1 >sp|Q9HCE1|MOV10_HUMAN Putative helicase MOV-10 OS=Hom 1 1MPDU1 O75352 >sp|O75352|MPU1_HUMAN Mannose-P-dolichol utilization defec 1 2

MPI P34949 >sp|P34949|MPI_HUMAN Mannose-6-phosphate isomerase OS=H 2 3MPO P05164 >sp|P05164|PERM_HUMAN Myeloperoxidase OS=Homo sapiens 8 14MPP1 Q00013 >sp|Q00013|EM55_HUMAN 55 kDa erythrocyte membrane protei 1 3MPP6 Q9NZW5 >sp|Q9NZW5|MPP6_HUMAN MAGUK p55 subfamily member 6 OS 2 2

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MPST P25325 >sp|P25325|THTM_HUMAN 3-mercaptopyruvate sulfurtransferas 6 10MRAS O14807 >sp|O14807|RASM_HUMAN Ras-related protein M-Ras OS=Homo 2 2MRC1 L8E7Q9 >tr|L8E7Q9|L8E7Q9_HUMAN Alternative protein MRC1 OS=Homo 1 1MRC1 P22897 >sp|P22897|MRC1_HUMAN Macrophage mannose receptor 1 OS 7 8MRC2 Q9UBG0 >sp|Q9UBG0|MRC2_HUMAN C-type mannose receptor 2 OS=Hom 1 1

MRGPRF Q96AM1 >sp|Q96AM1|MRGRF_HUMAN Mas-related G-protein coupled rec 1 1MRPL12 P52815 >sp|P52815|RM12_HUMAN 39S ribosomal protein L12, mitochon 1 1MRPL37 Q9BZE1 >sp|Q9BZE1|RM37_HUMAN 39S ribosomal protein L37, mitochon 1 2MRPS7 Q9Y2R9 >sp|Q9Y2R9|RT07_HUMAN 28S ribosomal protein S7, mitochond 1 1MSLN Q13421 >sp|Q13421|MSLN_HUMAN Mesothelin OS=Homo sapiens GN=M 2 4MSN P26038 >sp|P26038|MOES_HUMAN Moesin OS=Homo sapiens GN=MSN 35 115MT1A P04731 >sp|P04731|MT1A_HUMAN Metallothionein-1A OS=Homo sapien 1 2MT1E P04732 >sp|P04732|MT1E_HUMAN Metallothionein-1E OS=Homo sapien 1 5MTAP Q13126 >sp|Q13126|MTAP_HUMAN S-methyl-5'-thioadenosine phosphor 3 5

MT-ATP6 P00846 >sp|P00846|ATP6_HUMAN ATP synthase subunit a OS=Homo sa 1 1MTCH1 A4FVA6 >tr|A4FVA6|A4FVA6_HUMAN MTCH1 protein (Fragment) OS=Hom 1 1MTCH1 Q9NZJ7 >sp|Q9NZJ7|MTCH1_HUMAN Mitochondrial carrier homolog 1 O 1 2MTCH2 Q9Y6C9 >sp|Q9Y6C9|MTCH2_HUMAN Mitochondrial carrier homolog 2 O 4 10MT-CO1 P00395 >sp|P00395|COX1_HUMAN Cytochrome c oxidase subunit 1 OS= 1 1MT-CO2 P00403 >sp|P00403|COX2_HUMAN Cytochrome c oxidase subunit 2 OS= 1 7MTDH Q86UE4 >sp|Q86UE4|LYRIC_HUMAN Protein LYRIC OS=Homo sapiens G 1 2

MTHFD1 P11586 >sp|P11586|C1TC_HUMAN C-1-tetrahydrofolate synthase, cytop 22 56MTPN P58546 >sp|P58546|MTPN_HUMAN Myotrophin OS=Homo sapiens GN=M 2 10

MTRF1L H0UI12 >tr|H0UI12|H0UI12_HUMAN Mitochondrial translational release f 1 1MTURN Q8N3F0 >sp|Q8N3F0|MTURN_HUMAN Maturin OS=Homo sapiens GN=MT 1 1MTX1 H0Y6Y5 >tr|H0Y6Y5|H0Y6Y5_HUMAN Metaxin-1 OS=Homo sapiens GN=M 1 1MTX1 Q13505 >sp|Q13505|MTX1_HUMAN Metaxin-1 OS=Homo sapiens GN=MTX 1 1MUT P22033 >sp|P22033|MUTA_HUMAN Methylmalonyl-CoA mutase, mitochon 3 3MVP Q14764 >sp|Q14764|MVP_HUMAN Major vault protein OS=Homo sapiens 11 18

MXRA7 P84157 >sp|P84157|MXRA7_HUMAN Matrix-remodeling-associated prote 3 6MXRA7 P84157-2 >sp|P84157-2|MXRA7_HUMAN Isoform 2 of Matrix-remodeling-ass 1 3MYADM Q96S97 >sp|Q96S97|MYADM_HUMAN Myeloid-associated differentiation 3 9MYCLP1 P12525 >sp|P12525|MYCP1_HUMAN Putative myc-like protein MYCLP1 1 1MYEOV Q96EZ4 >sp|Q96EZ4|MYEOV_HUMAN Myeloma-overexpressed gene prot 1 1MYH10 P35580 >sp|P35580|MYH10_HUMAN Myosin-10 OS=Homo sapiens GN=M 47 159MYH11 P35749 >sp|P35749|MYH11_HUMAN Myosin-11 OS=Homo sapiens GN=M 44 135MYH14 Q7Z406 >sp|Q7Z406|MYH14_HUMAN Myosin-14 OS=Homo sapiens GN=M 7 9MYH7 P12883 >sp|P12883|MYH7_HUMAN Myosin-7 OS=Homo sapiens GN=MYH 1 1MYH9 P35579 >sp|P35579|MYH9_HUMAN Myosin-9 OS=Homo sapiens GN=MYH 102 512

MYL12A P19105 >sp|P19105|ML12A_HUMAN Myosin regulatory light chain 12A 11 64MYL6 P60660 >sp|P60660|MYL6_HUMAN Myosin light polypeptide 6 OS=Homo 9 47

MYL6B P14649 >sp|P14649|MYL6B_HUMAN Myosin light chain 6B OS=Homo sap 4 16MYL9 P24844 >sp|P24844|MYL9_HUMAN Myosin regulatory light polypeptide 4 15MYLK Q15746 >sp|Q15746|MYLK_HUMAN Myosin light chain kinase, smooth m 1 2

MYO18A Q92614 >sp|Q92614|MY18A_HUMAN Unconventional myosin-XVIIIa OS= 1 1MYO1B O43795 >sp|O43795|MYO1B_HUMAN Unconventional myosin-Ib OS=Hom 1 2MYO1C D3DTH7 >tr|D3DTH7|D3DTH7_HUMAN Myosin IC, isoform CRA_a OS=Ho 1 13MYO1C O00159 >sp|O00159|MYO1C_HUMAN Unconventional myosin-Ic OS=Hom 54 295MYO1C O00159-3 >sp|O00159-3|MYO1C_HUMAN Isoform 3 of Unconventional myos 1 3MYO5A Q9Y4I1 >sp|Q9Y4I1|MYO5A_HUMAN Unconventional myosin-Va OS=Hom 1 1MYOF Q9NZM1 >sp|Q9NZM1|MYOF_HUMAN Myoferlin OS=Homo sapiens GN=MY 7 9

MYPOP Q86VE0 >sp|Q86VE0|MYPOP_HUMAN Myb-related transcription factor, pa 1 3N/A A0A5E4 >tr|A0A5E4|A0A5E4_HUMAN Uncharacterized protein OS=Homo s 1 1N/A A2J1M4 >tr|A2J1M4|A2J1M4_HUMAN Rheumatoid factor RF-ET7 (Fragmen 1 5N/A A2J1N0 >tr|A2J1N0|A2J1N0_HUMAN Rheumatoid factor RF-IP14 (Fragmen 1 2N/A A2J1N2 >tr|A2J1N2|A2J1N2_HUMAN Rheumatoid factor RF-IP18 (Fragmen 1 1N/A A2J1N5 >tr|A2J1N5|A2J1N5_HUMAN Rheumatoid factor RF-ET6 (Fragmen 1 3N/A A2J1N6 >tr|A2J1N6|A2J1N6_HUMAN Rheumatoid factor RF-ET9 (Fragmen 1 6N/A A2JA19 >tr|A2JA19|A2JA19_HUMAN Anti-mucin1 light chain variable regi 1 7N/A A2NW97 >tr|A2NW97|A2NW97_HUMAN Rheumatoid factor Vh I region (Fra 1 1N/A A2NYU7 >tr|A2NYU7|A2NYU7_HUMAN Heavy chain Fab (Fragment) OS=Ho 1 1N/A A7L8C6 >tr|A7L8C6|A7L8C6_HUMAN Alpha-1-antitrypsin (Fragment) OS= 1 1N/A A8K6H1 >tr|A8K6H1|A8K6H1_HUMAN cDNA FLJ76662, highly similar to Homo 1 1N/A A8K787 >tr|A8K787|A8K787_HUMAN cDNA FLJ75273, highly similar to Homo s 1 1

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N/A A8K7N0 >tr|A8K7N0|A8K7N0_HUMAN cDNA FLJ75556, highly similar to Ho 1 3N/A A8K8C4 >tr|A8K8C4|A8K8C4_HUMAN cDNA FLJ77693, highly similar to Homo 1 1N/A A8K9P0 >tr|A8K9P0|A8K9P0_HUMAN cDNA FLJ78413, highly similar to H 1 14N/A B2R582 >tr|B2R582|B2R582_HUMAN cDNA, FLJ92374, highly similar to Ho 1 1N/A B2R6Y1 >tr|B2R6Y1|B2R6Y1_HUMAN Histone H3 OS=Homo sapiens PE=2 1 1N/A B2RDV2 >tr|B2RDV2|B2RDV2_HUMAN cDNA, FLJ96778, highly similar to H 1 1N/A B3KN06 >tr|B3KN06|B3KN06_HUMAN Coronin OS=Homo sapiens PE=2 SV 1 1N/A B3KSS2 >tr|B3KSS2|B3KSS2_HUMAN cDNA FLJ36849 fis, clone ASTRO20141 1 1N/A B3VL31 >tr|B3VL31|B3VL31_HUMAN Beta globin (Fragment) OS=Homo sa 1 2N/A B4DDH0 >tr|B4DDH0|B4DDH0_HUMAN cDNA FLJ55146, highly similar to 3 8N/A B4DI57 >tr|B4DI57|B4DI57_HUMAN cDNA FLJ54111, highly similar to Ser 2 4N/A B4DLA1 >tr|B4DLA1|B4DLA1_HUMAN cDNA FLJ53453, highly similar to EH- 1 2N/A B4DPR2 >tr|B4DPR2|B4DPR2_HUMAN cDNA FLJ50830, highly similar to S 2 17N/A B4DS79 >tr|B4DS79|B4DS79_HUMAN cDNA FLJ56828, highly similar to Adap 1 1N/A B4DSH0 >tr|B4DSH0|B4DSH0_HUMAN cDNA FLJ56240, highly similar to Dedi 1 1N/A B4DTF2 >tr|B4DTF2|B4DTF2_HUMAN Annexin OS=Homo sapiens PE=2 S 1 3N/A B4DUF4 >tr|B4DUF4|B4DUF4_HUMAN cDNA FLJ51684, moderately similar to 1 1N/A B4DVJ0 >tr|B4DVJ0|B4DVJ0_HUMAN Glucose-6-phosphate isomerase OS 1 1N/A B4DW52 >tr|B4DW52|B4DW52_HUMAN cDNA FLJ55253, highly similar to Ac 4 30N/A B4E106 >tr|B4E106|B4E106_HUMAN cDNA FLJ53399, highly similar to Mon 2 2N/A B4E1B2 >tr|B4E1B2|B4E1B2_HUMAN cDNA FLJ53691, highly similar to Ser 4 44N/A B7Z539 >tr|B7Z539|B7Z539_HUMAN cDNA FLJ56954, highly similar to Inter 1 2N/A E5KSE7 >tr|E5KSE7|E5KSE7_HUMAN Mitochondrial short-chain specific 1 1N/A F6KPG5 >tr|F6KPG5|F6KPG5_HUMAN Albumin (Fragment) OS=Homo sapi 2 109N/A G1FM90 >tr|G1FM90|G1FM90_HUMAN Anti-Influenza A hemagglutinin heavy 1 1N/A G3GAU4 >tr|G3GAU4|G3GAU4_HUMAN Anti-H1N1 influenza HA kappa chain 1 3N/A H1AE11 >tr|H1AE11|H1AE11_HUMAN Glycine-N-acyltransferase OS=Homo 1 1N/A P01593 >sp|P01593|KV101_HUMAN Ig kappa chain V-I region AG OS=Hom 3 29N/A P01596 >sp|P01596|KV104_HUMAN Ig kappa chain V-I region CAR OS=H 2 14N/A P01598 >sp|P01598|KV106_HUMAN Ig kappa chain V-I region EU OS=Hom 1 2N/A P01611 >sp|P01611|KV119_HUMAN Ig kappa chain V-I region Wes OS=Ho 2 9N/A P01613 >sp|P01613|KV121_HUMAN Ig kappa chain V-I region Ni OS=Hom 2 5N/A P01614 >sp|P01614|KV201_HUMAN Ig kappa chain V-II region Cum OS=H 2 9N/A P01615 >sp|P01615|KV202_HUMAN Ig kappa chain V-II region FR OS=Ho 1 1N/A P01617 >sp|P01617|KV204_HUMAN Ig kappa chain V-II region TEW OS=H 2 17N/A P01620 >sp|P01620|KV302_HUMAN Ig kappa chain V-III region SIE OS=H 4 33N/A P01624 >sp|P01624|KV306_HUMAN Ig kappa chain V-III region POM OS= 1 2N/A P01625 >sp|P01625|KV402_HUMAN Ig kappa chain V-IV region Len OS=H 2 22N/A P01700 >sp|P01700|LV102_HUMAN Ig lambda chain V-I region HA OS=Ho 1 6N/A P01714 >sp|P01714|LV301_HUMAN Ig lambda chain V-III region SH OS=H 1 3N/A P01715 >sp|P01715|LV401_HUMAN Ig lambda chain V-IV region Bau OS= 1 1N/A P01717 >sp|P01717|LV403_HUMAN Ig lambda chain V-IV region Hil OS=H 1 2N/A P01743 >sp|P01743|HV102_HUMAN Ig heavy chain V-I region HG3 OS=Ho 1 3N/A P01763 >sp|P01763|HV302_HUMAN Ig heavy chain V-III region WEA OS= 1 11N/A P01764 >sp|P01764|HV303_HUMAN Ig heavy chain V-III region VH26 OS 2 12N/A P01765 >sp|P01765|HV304_HUMAN Ig heavy chain V-III region TIL OS=H 1 10N/A P01766 >sp|P01766|HV305_HUMAN Ig heavy chain V-III region BRO OS= 1 15N/A P01767 >sp|P01767|HV306_HUMAN Ig heavy chain V-III region BUT OS= 1 2N/A P01770 >sp|P01770|HV309_HUMAN Ig heavy chain V-III region NIE OS=H 1 2N/A P01780 >sp|P01780|HV319_HUMAN Ig heavy chain V-III region JON OS= 1 1N/A P01781 >sp|P01781|HV320_HUMAN Ig heavy chain V-III region GAL OS= 2 16N/A P01814 >sp|P01814|HV201_HUMAN Ig heavy chain V-II region OU OS=Ho 1 4N/A P01825 >sp|P01825|HV207_HUMAN Ig heavy chain V-II region NEWM OS 1 3N/A P04211 >sp|P04211|LV001_HUMAN Ig lambda chain V region 4A OS=Hom 1 1N/A P04220 >sp|P04220|MUCB_HUMAN Ig mu heavy chain disease protein O 1 3N/A P04430 >sp|P04430|KV122_HUMAN Ig kappa chain V-I region BAN OS=Ho 1 1N/A P04433 >sp|P04433|KV309_HUMAN Ig kappa chain V-III region VG (Frag 2 8N/A P04434 >sp|P04434|KV310_HUMAN Ig kappa chain V-III region VH (Frag 1 1N/A P06331 >sp|P06331|HV209_HUMAN Ig heavy chain V-II region ARH-77 O 1 6N/A P80748 >sp|P80748|LV302_HUMAN Ig lambda chain V-III region LOI OS= 2 5N/A Q0ZCH6 >tr|Q0ZCH6|Q0ZCH6_HUMAN Immunglobulin heavy chain variable 1 1N/A Q0ZCI6 >tr|Q0ZCI6|Q0ZCI6_HUMAN Immunglobulin heavy chain variable 1 6N/A Q12938 >tr|Q12938|Q12938_HUMAN 12-lipoxygenase (Fragment) OS=Hom 1 1N/A Q56G89 >tr|Q56G89|Q56G89_HUMAN Serum albumin OS=Homo sapiens P 1 5

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N/A Q59EF6 >tr|Q59EF6|Q59EF6_HUMAN Calpain 2, large [catalytic] subunit v 2 12N/A Q59GM9 >tr|Q59GM9|Q59GM9_HUMAN Phosphorylase (Fragment) OS=Hom 1 1N/A Q6ZNW4 >tr|Q6ZNW4|Q6ZNW4_HUMAN CDNA FLJ27022 fis, clone SLV062 1 2N/A Q6ZTZ0 >tr|Q6ZTZ0|Q6ZTZ0_HUMAN cDNA FLJ44107 fis, clone TESTI40 1 1N/A Q6ZUJ7 >tr|Q6ZUJ7|Q6ZUJ7_HUMAN cDNA FLJ43649 fis, clone SYNOV40 1 1N/A Q6ZW64 >tr|Q6ZW64|Q6ZW64_HUMAN cDNA FLJ41552 fis, clone COLON20044 1 1N/A Q71RB1 >tr|Q71RB1|Q71RB1_HUMAN PP7080 OS=Homo sapiens PE=4 S 1 1N/A Q71U45 >tr|Q71U45|Q71U45_HUMAN Cytochrome c oxidase VIIc OS=Homo 2 4N/A Q86SX2 >tr|Q86SX2|Q86SX2_HUMAN Full-length cDNA clone CS0DL004YM19 1 10N/A Q86TT1 >tr|Q86TT1|Q86TT1_HUMAN Full-length cDNA clone CS0DD006YL0 1 7N/A Q86VZ9 >tr|Q86VZ9|Q86VZ9_HUMAN AngRem52 OS=Homo sapiens PE=2 1 1N/A Q96K68 >tr|Q96K68|Q96K68_HUMAN cDNA FLJ14473 fis, clone MAMMA1001 1 3N/A Q9HB02 >tr|Q9HB02|Q9HB02_HUMAN Ornithine decarboxylase antizyme 1 1N/A Q9HCC1 >tr|Q9HCC1|Q9HCC1_HUMAN Single chain Fv (Fragment) OS=Ho 1 7N/A Q9NPP6 >tr|Q9NPP6|Q9NPP6_HUMAN Immunoglobulin heavy chain variant 2 5N/A Q9UL77 >tr|Q9UL77|Q9UL77_HUMAN Myosin-reactive immunoglobulin light 1 1N/A Q9UL83 >tr|Q9UL83|Q9UL83_HUMAN Myosin-reactive immunoglobulin light 2 11N/A Q9UL86 >tr|Q9UL86|Q9UL86_HUMAN Myosin-reactive immunoglobulin kappa 1 2N/A Q9UL88 >tr|Q9UL88|Q9UL88_HUMAN Myosin-reactive immunoglobulin heavy 1 10N/A Q9UL89 >tr|Q9UL89|Q9UL89_HUMAN Myosin-reactive immunoglobulin heavy 1 1N/A Q9UL90 >tr|Q9UL90|Q9UL90_HUMAN Myosin-reactive immunoglobulin heavy 2 5N/A S6BGD4 >tr|S6BGD4|S6BGD4_HUMAN IgG H chain OS=Homo sapiens PE= 1 1N/A S6BGF5 >tr|S6BGF5|S6BGF5_HUMAN IgG H chain OS=Homo sapiens PE= 1 2

NACA Q13765 >sp|Q13765|NACA_HUMAN Nascent polypeptide-associated comp 3 6NAE1 Q13564 >sp|Q13564|ULA1_HUMAN NEDD8-activating enzyme E1 regulato 1 3NAGK Q9UJ70 >sp|Q9UJ70|NAGK_HUMAN N-acetyl-D-glucosamine kinase OS= 2 2NAGS Q8N159 >sp|Q8N159|NAGS_HUMAN N-acetylglutamate synthase, mitocho 1 1

NAMPT P43490 >sp|P43490|NAMPT_HUMAN Nicotinamide phosphoribosyltransf 3 4NAP1L1 P55209 >sp|P55209|NP1L1_HUMAN Nucleosome assembly protein 1-like 4 6NAP1L4 Q99733 >sp|Q99733|NP1L4_HUMAN Nucleosome assembly protein 1-like 3 4NAPA P54920 >sp|P54920|SNAA_HUMAN Alpha-soluble NSF attachment prote 6 14

NAPRT1 Q6XQN6 >sp|Q6XQN6|PNCB_HUMAN Nicotinate phosphoribosyltransfera 3 4NARS O43776 >sp|O43776|SYNC_HUMAN Asparagine--tRNA ligase, cytoplasm 1 1

NCAM2 L0R512 >tr|L0R512|L0R512_HUMAN Alternative protein NCAM2 OS=Hom 1 3NCBP1 Q09161 >sp|Q09161|NCBP1_HUMAN Nuclear cap-binding protein subuni 2 2

NCL P19338 >sp|P19338|NUCL_HUMAN Nucleolin OS=Homo sapiens GN=NCL 10 26NCLN Q969V3 >sp|Q969V3|NCLN_HUMAN Nicalin OS=Homo sapiens GN=NCLN 1 1ND5 R9Y4B7 >tr|R9Y4B7|R9Y4B7_HUMAN NADH-ubiquinone oxidoreductase c 1 2

NDRG1 Q92597 >sp|Q92597|NDRG1_HUMAN Protein NDRG1 OS=Homo sapiens 5 8NDRG2 Q9UN36 >sp|Q9UN36|NDRG2_HUMAN Protein NDRG2 OS=Homo sapiens 2 3

NDUFA10 O95299 >sp|O95299|NDUAA_HUMAN NADH dehydrogenase [ubiquinone] 1 1 4NDUFA13 Q9P0J0 >sp|Q9P0J0|NDUAD_HUMAN NADH dehydrogenase [ubiquinone] 1 3 5NDUFA2 O43678 >sp|O43678|NDUA2_HUMAN NADH dehydrogenase [ubiquinone] 1 2 2NDUFA4 O00483 >sp|O00483|NDUA4_HUMAN NADH dehydrogenase [ubiquinone] 1 3 14NDUFA5 Q16718 >sp|Q16718|NDUA5_HUMAN NADH dehydrogenase [ubiquinone] 1 4 5NDUFA6 P56556 >sp|P56556|NDUA6_HUMAN NADH dehydrogenase [ubiquinone] 1 1 2NDUFA8 P51970 >sp|P51970|NDUA8_HUMAN NADH dehydrogenase [ubiquinone] 1 2 11NDUFA9 Q16795 >sp|Q16795|NDUA9_HUMAN NADH dehydrogenase [ubiquinone] 1 a 3 5

NDUFAB1 O14561 >sp|O14561|ACPM_HUMAN Acyl carrier protein, mitochondrial 3 8NDUFAF2 Q8N183 >sp|Q8N183|MIMIT_HUMAN Mimitin, mitochondrial OS=Homo sa 1 1NDUFB1 O75438 >sp|O75438|NDUB1_HUMAN NADH dehydrogenase [ubiquinone] 1 1 1NDUFB10 O96000 >sp|O96000|NDUBA_HUMAN NADH dehydrogenase [ubiquinone] 1 4 5NDUFB4 O95168 >sp|O95168|NDUB4_HUMAN NADH dehydrogenase [ubiquinone] 1 3 6NDUFB6 O95139 >sp|O95139|NDUB6_HUMAN NADH dehydrogenase [ubiquinone] 1 1 1NDUFB7 P17568 >sp|P17568|NDUB7_HUMAN NADH dehydrogenase [ubiquinone] 1 2 3NDUFB9 Q9Y6M9 >sp|Q9Y6M9|NDUB9_HUMAN NADH dehydrogenase [ubiquinone] 1 1 1NDUFS1 P28331 >sp|P28331|NDUS1_HUMAN NADH-ubiquinone oxidoreductase 75 13 30NDUFS2 O75306 >sp|O75306|NDUS2_HUMAN NADH dehydrogenase [ubiquinone] iro 3 6NDUFS3 O75489 >sp|O75489|NDUS3_HUMAN NADH dehydrogenase [ubiquinone] iro 4 14NDUFS4 O43181 >sp|O43181|NDUS4_HUMAN NADH dehydrogenase [ubiquinone] iro 2 8NDUFS5 O43920 >sp|O43920|NDUS5_HUMAN NADH dehydrogenase [ubiquinone] ir 1 1NDUFS7 O75251 >sp|O75251|NDUS7_HUMAN NADH dehydrogenase [ubiquinone] iro 1 1NDUFS8 O00217 >sp|O00217|NDUS8_HUMAN NADH dehydrogenase [ubiquinone] iro 5 6NDUFV1 P49821 >sp|P49821|NDUV1_HUMAN NADH dehydrogenase [ubiquinone] fla 4 12

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NDUFV2 P19404 >sp|P19404|NDUV2_HUMAN NADH dehydrogenase [ubiquinone] fla 3 10NECAP1 Q8NC96 >sp|Q8NC96|NECP1_HUMAN Adaptin ear-binding coat-associate 1 1NEDD8 Q15843 >sp|Q15843|NEDD8_HUMAN NEDD8 OS=Homo sapiens GN=NED 1 2NEDD9 Q14511 >sp|Q14511|CASL_HUMAN Enhancer of filamentation 1 OS=Hom 1 4NEGR1 Q7Z3B1 >sp|Q7Z3B1|NEGR1_HUMAN Neuronal growth regulator 1 OS=H 1 1NEK2 P51955 >sp|P51955|NEK2_HUMAN Serine/threonine-protein kinase Nek 1 14NEK4 P51957 >sp|P51957|NEK4_HUMAN Serine/threonine-protein kinase Nek 1 1NEK6 Q9HC98 >sp|Q9HC98|NEK6_HUMAN Serine/threonine-protein kinase Nek 1 1NEK7 Q8TDX7 >sp|Q8TDX7|NEK7_HUMAN Serine/threonine-protein kinase Nek 2 2

NELFB Q8WX92 >sp|Q8WX92|NELFB_HUMAN Negative elongation factor B OS=H 1 1NELL2 Q99435-3 >sp|Q99435-3|NELL2_HUMAN Isoform 3 of Protein kinase C-bind 1 1NENF Q9UMX5 >sp|Q9UMX5|NENF_HUMAN Neudesin OS=Homo sapiens GN=NE 2 2NES P48681 >sp|P48681|NEST_HUMAN Nestin OS=Homo sapiens GN=NES PE 1 1

NEXN Q0ZGT2 >sp|Q0ZGT2|NEXN_HUMAN Nexilin OS=Homo sapiens GN=NEXN 2 2NHP2L1 P55769 >sp|P55769|NH2L1_HUMAN NHP2-like protein 1 OS=Homo sapie 1 1

NID1 P14543 >sp|P14543|NID1_HUMAN Nidogen-1 OS=Homo sapiens GN=NID1 24 91NID2 Q14112 >sp|Q14112|NID2_HUMAN Nidogen-2 OS=Homo sapiens GN=NID 20 44

NIF3L1 Q9GZT8 >sp|Q9GZT8|GTPC1_HUMAN Putative GTP cyclohydrolase 1 type 2 2NIPSNAP1 Q9BPW8 >sp|Q9BPW8|NIPS1_HUMAN Protein NipSnap homolog 1 OS=Ho 1 1

NIPSNAP3A Q9UFN0 >sp|Q9UFN0|NPS3A_HUMAN Protein NipSnap homolog 3A OS=H 6 14NIPSNAP3B Q9BS92 >sp|Q9BS92|NPS3B_HUMAN Protein NipSnap homolog 3B OS=H 1 1

NIT1 Q86X76 >sp|Q86X76|NIT1_HUMAN Nitrilase homolog 1 OS=Homo sapiens 2 6NIT2 Q9NQR4 >sp|Q9NQR4|NIT2_HUMAN Omega-amidase NIT2 OS=Homo sapie 7 12

NLRP13 Q86W25 >sp|Q86W25|NAL13_HUMAN NACHT, LRR and PYD domains-conta 1 1NME1 P15531 >sp|P15531|NDKA_HUMAN Nucleoside diphosphate kinase A OS 6 14NME2 P22392 >sp|P22392|NDKB_HUMAN Nucleoside diphosphate kinase B OS 2 6

NME2P1 O60361 >sp|O60361|NDK8_HUMAN Putative nucleoside diphosphate kin 4 29NMT1 P30419 >sp|P30419|NMT1_HUMAN Glycylpeptide N-tetradecanoyltransf 5 8NNMT P40261 >sp|P40261|NNMT_HUMAN Nicotinamide N-methyltransferase O 3 6NNT Q13423 >sp|Q13423|NNTM_HUMAN NAD(P) transhydrogenase, mitochond 15 30

NOA1 Q8NC60 >sp|Q8NC60|NOA1_HUMAN Nitric oxide-associated protein 1 O 1 1NOL3 O60936 >sp|O60936|NOL3_HUMAN Nucleolar protein 3 OS=Homo sapien 1 1NOL3 O60936-2 >sp|O60936-2|NOL3_HUMAN Isoform 2 of Nucleolar protein 3 O 1 2

NOMO1 Q15155 >sp|Q15155|NOMO1_HUMAN Nodal modulator 1 OS=Homo sapi 1 1NONO Q15233 >sp|Q15233|NONO_HUMAN Non-POU domain-containing octamer- 1 1NPAS2 Q99743 >sp|Q99743|NPAS2_HUMAN Neuronal PAS domain-containing pr 1 1NPC2 P61916 >sp|P61916|NPC2_HUMAN Epididymal secretory protein E1 OS= 2 3

NPEPL1 Q8NDH3 >sp|Q8NDH3|PEPL1_HUMAN Probable aminopeptidase NPEPL1 2 3NPEPPS P55786 >sp|P55786|PSA_HUMAN Puromycin-sensitive aminopeptidase 9 22

NPEPPSL1 A6NEC2 >sp|A6NEC2|PSAL_HUMAN Puromycin-sensitive aminopeptidase- 4 6NPLOC4 Q8TAT6 >sp|Q8TAT6|NPL4_HUMAN Nuclear protein localization protein 2 4

NPM1 P06748 >sp|P06748|NPM_HUMAN Nucleophosmin OS=Homo sapiens GN 10 31NPR2 P20594 >sp|P20594|ANPRB_HUMAN Atrial natriuretic peptide receptor 1 1NPTN Q9Y639 >sp|Q9Y639|NPTN_HUMAN Neuroplastin OS=Homo sapiens GN= 3 5NQO1 P15559 >sp|P15559|NQO1_HUMAN NAD(P)H dehydrogenase [quinone] 1 12 36NQO2 P16083 >sp|P16083|NQO2_HUMAN Ribosyldihydronicotinamide dehydrog 4 8

NSDHL Q15738 >sp|Q15738|NSDHL_HUMAN Sterol-4-alpha-carboxylate 3-dehydr 1 1NSF P46459 >sp|P46459|NSF_HUMAN Vesicle-fusing ATPase OS=Homo sapi 1 1

NSFL1C Q9UNZ2 >sp|Q9UNZ2|NSF1C_HUMAN NSFL1 cofactor p47 OS=Homo sapi 3 3NT5E P21589 >sp|P21589|5NTD_HUMAN 5'-nucleotidase OS=Homo sapiens G 3 10NTM Q9P121 >sp|Q9P121|NTRI_HUMAN Neurotrimin OS=Homo sapiens GN=N 1 1

NUCB1 Q02818 >sp|Q02818|NUCB1_HUMAN Nucleobindin-1 OS=Homo sapiens 2 6NUCKS1 Q9H1E3 >sp|Q9H1E3|NUCKS_HUMAN Nuclear ubiquitous casein and cycli 1 2

NUDC Q9Y266 >sp|Q9Y266|NUDC_HUMAN Nuclear migration protein nudC OS= 1 1NUDCD1 Q96RS6 >sp|Q96RS6|NUDC1_HUMAN NudC domain-containing protein 1 1 1NUDT5 Q9UKK9 >sp|Q9UKK9|NUDT5_HUMAN ADP-sugar pyrophosphatase OS=H 4 7NUDT6 P53370 >sp|P53370|NUDT6_HUMAN Nucleoside diphosphate-linked moie 1 3NUMA1 Q14980 >sp|Q14980|NUMA1_HUMAN Nuclear mitotic apparatus protein 2 3NUP155 O75694 >sp|O75694|NU155_HUMAN Nuclear pore complex protein Nup1 1 1NUP205 Q92621 >sp|Q92621|NU205_HUMAN Nuclear pore complex protein Nup2 1 1NUTF2 P61970 >sp|P61970|NTF2_HUMAN Nuclear transport factor 2 OS=Homo 4 8OAT P04181 >sp|P04181|OAT_HUMAN Ornithine aminotransferase, mitochond 1 1

OCIAD1 Q9NX40 >sp|Q9NX40|OCAD1_HUMAN OCIA domain-containing protein 1 1 1OGDH Q02218 >sp|Q02218|ODO1_HUMAN 2-oxoglutarate dehydrogenase, mitoc 17 31

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OGN P20774 >sp|P20774|MIME_HUMAN Mimecan OS=Homo sapiens GN=OGN 10 60OLA1 Q9NTK5 >sp|Q9NTK5|OLA1_HUMAN Obg-like ATPase 1 OS=Homo sapien 5 9

OLFML1 Q6UWY5 >sp|Q6UWY5|OLFL1_HUMAN Olfactomedin-like protein 1 OS=Ho 6 12OLFML3 Q9NRN5 >sp|Q9NRN5|OLFL3_HUMAN Olfactomedin-like protein 3 OS=Ho 4 4

OPA1 O60313 >sp|O60313|OPA1_HUMAN Dynamin-like 120 kDa protein, mitoch 5 6OPLAH O14841 >sp|O14841|OPLA_HUMAN 5-oxoprolinase OS=Homo sapiens G 1 2OPTN Q96CV9 >sp|Q96CV9|OPTN_HUMAN Optineurin OS=Homo sapiens GN=O 1 1

OR2M4 Q96R27 >sp|Q96R27|OR2M4_HUMAN Olfactory receptor 2M4 OS=Homo s 1 1ORM1 P02763 >sp|P02763|A1AG1_HUMAN Alpha-1-acid glycoprotein 1 OS=Ho 12 134ORM2 P19652 >sp|P19652|A1AG2_HUMAN Alpha-1-acid glycoprotein 2 OS=Ho 7 40

OSBPL3 Q9H4L5 >sp|Q9H4L5|OSBL3_HUMAN Oxysterol-binding protein-related p 1 2OSGIN2 Q9Y236 >sp|Q9Y236|OSGI2_HUMAN Oxidative stress-induced growth inh 1 1OSTC Q9NRP0 >sp|Q9NRP0|OSTC_HUMAN Oligosaccharyltransferase complex 1 2OSTF1 Q92882 >sp|Q92882|OSTF1_HUMAN Osteoclast-stimulating factor 1 OS 2 4OTUB1 Q96FW1 >sp|Q96FW1|OTUB1_HUMAN Ubiquitin thioesterase OTUB1 OS= 3 3OXCT1 P55809 >sp|P55809|SCOT1_HUMAN Succinyl-CoA:3-ketoacid coenzyme A 8 16OXR1 Q8N573 >sp|Q8N573|OXR1_HUMAN Oxidation resistance protein 1 OS=H 1 1

OXSR1 O95747 >sp|O95747|OXSR1_HUMAN Serine/threonine-protein kinase O 2 2P4HB P07237 >sp|P07237|PDIA1_HUMAN Protein disulfide-isomerase OS=Hom 31 147

PA2G4 Q9UQ80 >sp|Q9UQ80|PA2G4_HUMAN Proliferation-associated protein 2 5 7PABPC1 P11940 >sp|P11940|PABP1_HUMAN Polyadenylate-binding protein 1 OS 7 10PACSIN2 Q9UNF0 >sp|Q9UNF0|PACN2_HUMAN Protein kinase C and casein kinase s 1 1

PAFAH1B1 P43034 >sp|P43034|LIS1_HUMAN Platelet-activating factor acetylhydro 7 14PAFAH1B2 P68402 >sp|P68402|PA1B2_HUMAN Platelet-activating factor acetylhydr 3 11

PAICS P22234 >sp|P22234|PUR6_HUMAN Multifunctional protein ADE2 OS=Hom 3 3PAK2 Q13177 >sp|Q13177|PAK2_HUMAN Serine/threonine-protein kinase PAK 1 3PALM O75781 >sp|O75781|PALM_HUMAN Paralemmin-1 OS=Homo sapiens GN 9 27

PALMD Q9NP74 >sp|Q9NP74|PALMD_HUMAN Palmdelphin OS=Homo sapiens GN 4 8PANK4 Q9NVE7 >sp|Q9NVE7|PANK4_HUMAN Pantothenate kinase 4 OS=Homo s 1 1PARK7 Q99497 >sp|Q99497|PARK7_HUMAN Protein DJ-1 OS=Homo sapiens GN 15 83PARP1 P09874 >sp|P09874|PARP1_HUMAN Poly [ADP-ribose] polymerase 1 OS 1 1PARVA Q9NVD7 >sp|Q9NVD7|PARVA_HUMAN Alpha-parvin OS=Homo sapiens G 9 52PAWR Q96IZ0 >sp|Q96IZ0|PAWR_HUMAN PRKC apoptosis WT1 regulator prot 1 1

PC P11498 >sp|P11498|PYC_HUMAN Pyruvate carboxylase, mitochondrial 17 27PCBD1 P61457 >sp|P61457|PHS_HUMAN Pterin-4-alpha-carbinolamine dehydra 2 5PCBP1 Q15365 >sp|Q15365|PCBP1_HUMAN Poly(rC)-binding protein 1 OS=Hom 11 26PCBP2 Q15366 >sp|Q15366|PCBP2_HUMAN Poly(rC)-binding protein 2 OS=Hom 4 9PCCA P05165 >sp|P05165|PCCA_HUMAN Propionyl-CoA carboxylase alpha chai 3 3PCCB P05166 >sp|P05166|PCCB_HUMAN Propionyl-CoA carboxylase beta chain 3 7

PCDH1 Q08174 >sp|Q08174|PCDH1_HUMAN Protocadherin-1 OS=Homo sapiens 1 1PCK2 Q16822 >sp|Q16822|PCKGM_HUMAN Phosphoenolpyruvate carboxykinase 5 7

PCMT1 P22061 >sp|P22061|PIMT_HUMAN Protein-L-isoaspartate(D-aspartate) O 3 6PCOLCE Q15113 >sp|Q15113|PCOC1_HUMAN Procollagen C-endopeptidase enha 1 2PCYOX1 Q9UHG3 >sp|Q9UHG3|PCYOX_HUMAN Prenylcysteine oxidase 1 OS=Hom 21 82PCYT2 Q99447 >sp|Q99447|PCY2_HUMAN Ethanolamine-phosphate cytidylyltra 3 6PDAP1 Q13442 >sp|Q13442|HAP28_HUMAN 28 kDa heat- and acid-stable phosp 2 5PDCD4 Q53EL6 >sp|Q53EL6|PDCD4_HUMAN Programmed cell death protein 4 O 2 2PDCD5 O14737 >sp|O14737|PDCD5_HUMAN Programmed cell death protein 5 O 2 4PDCD6 O75340 >sp|O75340|PDCD6_HUMAN Programmed cell death protein 6 O 3 9

PDCD6IP Q8WUM4 >sp|Q8WUM4|PDC6I_HUMAN Programmed cell death 6-interactin 12 23PDE1B Q01064 >sp|Q01064|PDE1B_HUMAN Calcium/calmodulin-dependent 3',5'-c 1 1

PDGFRA P16234 >sp|P16234|PGFRA_HUMAN Platelet-derived growth factor rece 1 1PDHA1 P08559 >sp|P08559|ODPA_HUMAN Pyruvate dehydrogenase E1 component 3 5PDHA2 P29803 >sp|P29803|ODPAT_HUMAN Pyruvate dehydrogenase E1 component 1 2PDHB P11177 >sp|P11177|ODPB_HUMAN Pyruvate dehydrogenase E1 component 7 20PDHX O00330 >sp|O00330|ODPX_HUMAN Pyruvate dehydrogenase protein X co 1 1PDIA3 H7BZJ3 >tr|H7BZJ3|H7BZJ3_HUMAN Thioredoxin (Fragment) OS=Homo s 1 10PDIA3 P30101 >sp|P30101|PDIA3_HUMAN Protein disulfide-isomerase A3 OS= 34 129PDIA4 P13667 >sp|P13667|PDIA4_HUMAN Protein disulfide-isomerase A4 OS= 13 26PDIA6 Q15084 >sp|Q15084|PDIA6_HUMAN Protein disulfide-isomerase A6 OS= 10 46

PDLIM1 O00151 >sp|O00151|PDLI1_HUMAN PDZ and LIM domain protein 1 OS=H 8 16PDLIM2 Q96JY6 >sp|Q96JY6|PDLI2_HUMAN PDZ and LIM domain protein 2 OS=H 1 1PDLIM7 Q9NR12 >sp|Q9NR12|PDLI7_HUMAN PDZ and LIM domain protein 7 OS=H 1 1PDXK O00764 >sp|O00764|PDXK_HUMAN Pyridoxal kinase OS=Homo sapiens 7 23

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PEA15 Q15121 >sp|Q15121|PEA15_HUMAN Astrocytic phosphoprotein PEA-15 8 16PEBP1 P30086 >sp|P30086|PEBP1_HUMAN Phosphatidylethanolamine-binding p 11 87

PECAM1 P16284 >sp|P16284|PECA1_HUMAN Platelet endothelial cell adhesion 7 11PEPD P12955 >sp|P12955|PEPD_HUMAN Xaa-Pro dipeptidase OS=Homo sapie 6 9PEX14 O75381 >sp|O75381|PEX14_HUMAN Peroxisomal membrane protein PEX 1 1PEX19 P40855 >sp|P40855|PEX19_HUMAN Peroxisomal biogenesis factor 19 O 3 4PFAS H0YGH1 >tr|H0YGH1|H0YGH1_HUMAN Phosphoribosylformylglycinamidine 1 2

PFDN1 O60925 >sp|O60925|PFD1_HUMAN Prefoldin subunit 1 OS=Homo sapien 1 2PFDN2 Q9UHV9 >sp|Q9UHV9|PFD2_HUMAN Prefoldin subunit 2 OS=Homo sapie 1 7PFDN4 Q9NQP4 >sp|Q9NQP4|PFD4_HUMAN Prefoldin subunit 4 OS=Homo sapie 2 5PFDN6 O15212 >sp|O15212|PFD6_HUMAN Prefoldin subunit 6 OS=Homo sapien 2 4PFKL P17858 >sp|P17858|K6PL_HUMAN 6-phosphofructokinase, liver type OS 10 25PFKM P08237 >sp|P08237|K6PF_HUMAN 6-phosphofructokinase, muscle type 3 5PFKP Q01813 >sp|Q01813|K6PP_HUMAN 6-phosphofructokinase type C OS=Ho 2 2PFN1 P07737 >sp|P07737|PROF1_HUMAN Profilin-1 OS=Homo sapiens GN=PF 12 80PFN2 P35080 >sp|P35080|PROF2_HUMAN Profilin-2 OS=Homo sapiens GN=PF 1 1

PGAM1 P18669 >sp|P18669|PGAM1_HUMAN Phosphoglycerate mutase 1 OS=Ho 15 70PGD P52209 >sp|P52209|6PGD_HUMAN 6-phosphogluconate dehydrogenase, d 23 104

PGK1 P00558 >sp|P00558|PGK1_HUMAN Phosphoglycerate kinase 1 OS=Homo 28 211PGLS O95336 >sp|O95336|6PGL_HUMAN 6-phosphogluconolactonase OS=Homo 8 28

PGLYRP2 Q96PD5 >sp|Q96PD5|PGRP2_HUMAN N-acetylmuramoyl-L-alanine amida 2 6PGM1 P36871 >sp|P36871|PGM1_HUMAN Phosphoglucomutase-1 OS=Homo sa 30 142PGM2 Q96G03 >sp|Q96G03|PGM2_HUMAN Phosphoglucomutase-2 OS=Homo sa 2 3PGM3 O95394 >sp|O95394|AGM1_HUMAN Phosphoacetylglucosamine mutase 1 1PGM5 Q15124 >sp|Q15124|PGM5_HUMAN Phosphoglucomutase-like protein 5 3 4

PGRMC1 O00264 >sp|O00264|PGRC1_HUMAN Membrane-associated progesterone 8 23PGRMC2 O15173 >sp|O15173|PGRC2_HUMAN Membrane-associated progesterone 9 25

PHB P35232 >sp|P35232|PHB_HUMAN Prohibitin OS=Homo sapiens GN=PHB 16 43PHB2 Q99623 >sp|Q99623|PHB2_HUMAN Prohibitin-2 OS=Homo sapiens GN=P 15 42PHC3 Q8NDX5 >sp|Q8NDX5|PHC3_HUMAN Polyhomeotic-like protein 3 OS=Hom 1 1

PHGDH O43175 >sp|O43175|SERA_HUMAN D-3-phosphoglycerate dehydrogenas 17 80PHLDB1 Q86UU1 >sp|Q86UU1|PHLB1_HUMAN Pleckstrin homology-like domain fa 7 11PHLDB1 Q86UU1-2 >sp|Q86UU1-2|PHLB1_HUMAN Isoform 2 of Pleckstrin homology-l 1 1PHPT1 Q9NRX4 >sp|Q9NRX4|PHP14_HUMAN 14 kDa phosphohistidine phosphat 1 1

PHYKPL Q8IUZ5 >sp|Q8IUZ5|AT2L2_HUMAN 5-phosphohydroxy-L-lysine phospho 1 1PI16 Q6UXB8 >sp|Q6UXB8|PI16_HUMAN Peptidase inhibitor 16 OS=Homo sapi 1 1

PI4KA P42356 >sp|P42356|PI4KA_HUMAN Phosphatidylinositol 4-kinase alpha 1 2PICALM Q13492 >sp|Q13492|PICAL_HUMAN Phosphatidylinositol-binding clathri 2 3PIK3R3 Q92569 >sp|Q92569|P55G_HUMAN Phosphatidylinositol 3-kinase regulat 1 1

PIN1 Q13526 >sp|Q13526|PIN1_HUMAN Peptidyl-prolyl cis-trans isomerase NI 1 1PIP4K2C Q8TBX8 >sp|Q8TBX8|PI42C_HUMAN Phosphatidylinositol 5-phosphate 4- 1 1

PIR O00625 >sp|O00625|PIR_HUMAN Pirin OS=Homo sapiens GN=PIR PE=1 2 3PITHD1 Q9GZP4 >sp|Q9GZP4|PITH1_HUMAN PITH domain-containing protein 1 1 4PITPNB P48739 >sp|P48739|PIPNB_HUMAN Phosphatidylinositol transfer protein 3 4PITRM1 Q5JRX3-2 >sp|Q5JRX3-2|PREP_HUMAN Isoform 2 of Presequence protease, 1 1PITX1 P78337 >sp|P78337|PITX1_HUMAN Pituitary homeobox 1 OS=Homo sapi 1 1PKM P14618 >sp|P14618|KPYM_HUMAN Pyruvate kinase PKM OS=Homo sapi 34 169PKM P14618-2 >sp|P14618-2|KPYM_HUMAN Isoform M1 of Pyruvate kinase PK 1 1

PLA2G4C Q9UP65 >sp|Q9UP65|PA24C_HUMAN Cytosolic phospholipase A2 gamma 1 1PLA2G4E B7WPN2 >tr|B7WPN2|B7WPN2_HUMAN Cytosolic phospholipase A2 epsil 2 3

PLCB3 Q01970 >sp|Q01970|PLCB3_HUMAN 1-phosphatidylinositol 4,5-bisphosph 1 1PLCD1 P51178 >sp|P51178|PLCD1_HUMAN 1-phosphatidylinositol 4,5-bisphosph 1 1PLCH1 Q4KWH8 >sp|Q4KWH8|PLCH1_HUMAN 1-phosphatidylinositol 4,5-bisphosp 1 1PLD3 Q8IV08 >sp|Q8IV08|PLD3_HUMAN Phospholipase D3 OS=Homo sapiens 1 1PLEC Q15149 >sp|Q15149|PLEC_HUMAN Plectin OS=Homo sapiens GN=PLEC 55 86

PLEKHG4B Q96PX9 >sp|Q96PX9|PKH4B_HUMAN Pleckstrin homology domain-contai 1 2PLEKHO2 Q8TD55 >sp|Q8TD55|PKHO2_HUMAN Pleckstrin homology domain-contain 3 7

PLG P00747 >sp|P00747|PLMN_HUMAN Plasminogen OS=Homo sapiens GN= 14 29PLGRKT Q9HBL7 >sp|Q9HBL7|PLRKT_HUMAN Plasminogen receptor (KT) OS=Hom 1 1

PLIN1 O60240 >sp|O60240|PLIN1_HUMAN Perilipin-1 OS=Homo sapiens GN=PL 38 466PLIN3 O60664 >sp|O60664|PLIN3_HUMAN Perilipin-3 OS=Homo sapiens GN=PL 4 8PLIN4 Q96Q06 >sp|Q96Q06|PLIN4_HUMAN Perilipin-4 OS=Homo sapiens GN=PL 94 719PLIN4 Q96Q06-2 >sp|Q96Q06-2|PLIN4_HUMAN Isoform 2 of Perilipin-4 OS=Homo s 1 13PLP2 Q04941 >sp|Q04941|PLP2_HUMAN Proteolipid protein 2 OS=Homo sapie 2 7

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PLS1 Q14651 >sp|Q14651|PLSI_HUMAN Plastin-1 OS=Homo sapiens GN=PLS1 3 10PLS3 P13797 >sp|P13797|PLST_HUMAN Plastin-3 OS=Homo sapiens GN=PLS3 14 28

PLSCR4 Q9NRQ2 >sp|Q9NRQ2|PLS4_HUMAN Phospholipid scramblase 4 OS=Homo 1 1PLTP P55058 >sp|P55058|PLTP_HUMAN Phospholipid transfer protein OS=Hom 2 2

PLVAP Q9BX97 >sp|Q9BX97|PLVAP_HUMAN Plasmalemma vesicle-associated pr 1 2PLXNC1 O60486 >sp|O60486|PLXC1_HUMAN Plexin-C1 OS=Homo sapiens GN=PL 1 1PLXND1 Q9Y4D7 >sp|Q9Y4D7|PLXD1_HUMAN Plexin-D1 OS=Homo sapiens GN=P 1 1

PML P29590 >sp|P29590|PML_HUMAN Protein PML OS=Homo sapiens GN=PM 6 7PNP P00491 >sp|P00491|PNPH_HUMAN Purine nucleoside phosphorylase OS 3 10

PNPLA2 Q96AD5 >sp|Q96AD5|PLPL2_HUMAN Patatin-like phospholipase domain-c 1 2PODXL O00592 >sp|O00592|PODXL_HUMAN Podocalyxin OS=Homo sapiens GN 2 4POFUT1 Q9H488 >sp|Q9H488|OFUT1_HUMAN GDP-fucose protein O-fucosyltrans 1 2

PON1 P27169 >sp|P27169|PON1_HUMAN Serum paraoxonase/arylesterase 1 O 6 12PON2 Q15165 >sp|Q15165|PON2_HUMAN Serum paraoxonase/arylesterase 2 1 5POP1 Q99575 >sp|Q99575|POP1_HUMAN Ribonucleases P/MRP protein subuni 1 1POR P16435 >sp|P16435|NCPR_HUMAN NADPH--cytochrome P450 reductase 5 12

POSTN Q15063 >sp|Q15063|POSTN_HUMAN Periostin OS=Homo sapiens GN=PO 4 10POSTN Q15063-3 >sp|Q15063-3|POSTN_HUMAN Isoform 3 of Periostin OS=Homo 1 2POTEI P0CG38 >sp|P0CG38|POTEI_HUMAN POTE ankyrin domain family member 1 12POTEJ P0CG39 >sp|P0CG39|POTEJ_HUMAN POTE ankyrin domain family membe 1 3

POTEKP Q9BYX7 >sp|Q9BYX7|ACTBM_HUMAN Putative beta-actin-like protein 3 3 29PPA1 Q15181 >sp|Q15181|IPYR_HUMAN Inorganic pyrophosphatase OS=Homo 10 34PPA2 Q9H2U2 >sp|Q9H2U2|IPYR2_HUMAN Inorganic pyrophosphatase 2, mitoc 3 4PPIA P62937 >sp|P62937|PPIA_HUMAN Peptidyl-prolyl cis-trans isomerase A 16 155

PPIAL4A Q9Y536 >sp|Q9Y536|PAL4A_HUMAN Peptidyl-prolyl cis-trans isomerase 6 43PPIB P23284 >sp|P23284|PPIB_HUMAN Peptidyl-prolyl cis-trans isomerase B 15 52PPL O60437 >sp|O60437|PEPL_HUMAN Periplakin OS=Homo sapiens GN=PPL 6 7

PPM1B O75688 >sp|O75688|PPM1B_HUMAN Protein phosphatase 1B OS=Homo 1 3PPM1F A8MX49 >tr|A8MX49|A8MX49_HUMAN Protein phosphatase 1F OS=Homo 1 1PPM1F P49593 >sp|P49593|PPM1F_HUMAN Protein phosphatase 1F OS=Homo s 3 4PPME1 Q9Y570 >sp|Q9Y570|PPME1_HUMAN Protein phosphatase methylesteras 1 1

PPP1CA P62136 >sp|P62136|PP1A_HUMAN Serine/threonine-protein phosphatase 11 24PPP1CB P62140 >sp|P62140|PP1B_HUMAN Serine/threonine-protein phosphatase 3 4

PPP1R12A O14974 >sp|O14974|MYPT1_HUMAN Protein phosphatase 1 regulatory s 3 3PPP1R12C Q9BZL4 >sp|Q9BZL4|PP12C_HUMAN Protein phosphatase 1 regulatory s 1 1PPP1R14A Q96A00 >sp|Q96A00|PP14A_HUMAN Protein phosphatase 1 regulatory s 1 1PPP1R18 Q6NYC8 >sp|Q6NYC8|PPR18_HUMAN Phostensin OS=Homo sapiens GN= 1 1PPP1R1B Q9UD71 >sp|Q9UD71|PPR1B_HUMAN Protein phosphatase 1 regulatory s 1 1PPP1R7 Q15435 >sp|Q15435|PP1R7_HUMAN Protein phosphatase 1 regulatory s 3 5PPP2CA P67775 >sp|P67775|PP2AA_HUMAN Serine/threonine-protein phosphatase 7 13PPP2CB P62714 >sp|P62714|PP2AB_HUMAN Serine/threonine-protein phosphatase 1 2

PPP2R1A P30153 >sp|P30153|2AAA_HUMAN Serine/threonine-protein phosphatase 15 39PPP2R4 Q15257 >sp|Q15257|PTPA_HUMAN Serine/threonine-protein phosphatase 1 4PPP3CA Q08209 >sp|Q08209|PP2BA_HUMAN Serine/threonine-protein phosphatase 4 6PPP6C O00743 >sp|O00743|PPP6_HUMAN Serine/threonine-protein phosphatase 1 2PPT1 P50897 >sp|P50897|PPT1_HUMAN Palmitoyl-protein thioesterase 1 OS= 1 4

PRAMEF12 O95522 >sp|O95522|PRA12_HUMAN PRAME family member 12 OS=Homo 1 1PRDX1 Q06830 >sp|Q06830|PRDX1_HUMAN Peroxiredoxin-1 OS=Homo sapiens 17 117PRDX2 P32119 >sp|P32119|PRDX2_HUMAN Peroxiredoxin-2 OS=Homo sapiens 12 128PRDX3 P30048 >sp|P30048|PRDX3_HUMAN Thioredoxin-dependent peroxide redu 8 39PRDX4 Q13162 >sp|Q13162|PRDX4_HUMAN Peroxiredoxin-4 OS=Homo sapiens 6 16PRDX5 P30044 >sp|P30044|PRDX5_HUMAN Peroxiredoxin-5, mitochondrial OS 11 31PRDX6 P30041 >sp|P30041|PRDX6_HUMAN Peroxiredoxin-6 OS=Homo sapiens 21 181PREB Q9HCU5 >sp|Q9HCU5|PREB_HUMAN Prolactin regulatory element-binding 1 1PRELP P51888 >sp|P51888|PRELP_HUMAN Prolargin OS=Homo sapiens GN=PR 15 165PREP P48147 >sp|P48147|PPCE_HUMAN Prolyl endopeptidase OS=Homo sapi 1 1

PRKACA P17612 >sp|P17612|KAPCA_HUMAN cAMP-dependent protein kinase cata 11 20PRKACB P22694 >sp|P22694|KAPCB_HUMAN cAMP-dependent protein kinase cata 1 1

PRKAR1A P10644 >sp|P10644|KAP0_HUMAN cAMP-dependent protein kinase type I 2 3PRKAR2A P13861 >sp|P13861|KAP2_HUMAN cAMP-dependent protein kinase type II 12 44PRKAR2B P31323 >sp|P31323|KAP3_HUMAN cAMP-dependent protein kinase type II 25 99

PRKCD Q05655 >sp|Q05655|KPCD_HUMAN Protein kinase C delta type OS=Hom 1 2PRKCDBP Q969G5 >sp|Q969G5|PRDBP_HUMAN Protein kinase C delta-binding pro 13 59PRKCSH P14314 >sp|P14314|GLU2B_HUMAN Glucosidase 2 subunit beta OS=Ho 21 64

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PRKD3 O94806 >sp|O94806|KPCD3_HUMAN Serine/threonine-protein kinase D3 1 1PRKDC P78527 >sp|P78527|PRKDC_HUMAN DNA-dependent protein kinase catal 8 8PRMT6 Q96LA8 >sp|Q96LA8|ANM6_HUMAN Protein arginine N-methyltransferas 1 1PROCR Q9UNN8 >sp|Q9UNN8|EPCR_HUMAN Endothelial protein C receptor OS= 3 8PROSC O94903 >sp|O94903|PROSC_HUMAN Proline synthase co-transcribed bac 2 2PRPH P41219 >sp|P41219|PERI_HUMAN Peripherin OS=Homo sapiens GN=PRP 5 93PRPS1 P60891 >sp|P60891|PRPS1_HUMAN Ribose-phosphate pyrophosphokina 2 4

PRPSAP1 Q14558 >sp|Q14558|KPRA_HUMAN Phosphoribosyl pyrophosphate syntha 1 1PRSS1 P07477 >sp|P07477|TRY1_HUMAN Trypsin-1 OS=Homo sapiens GN=PRS 1 10PRTN3 P24158 >sp|P24158|PRTN3_HUMAN Myeloblastin OS=Homo sapiens GN 2 2PSAP P07602 >sp|P07602|SAP_HUMAN Prosaposin OS=Homo sapiens GN=PSA 10 43PSAT1 Q9Y617 >sp|Q9Y617|SERC_HUMAN Phosphoserine aminotransferase OS 1 1PSEN2 P49810 >sp|P49810|PSN2_HUMAN Presenilin-2 OS=Homo sapiens GN=P 1 2PSMA1 P25786 >sp|P25786|PSA1_HUMAN Proteasome subunit alpha type-1 OS 11 24PSMA2 P25787 >sp|P25787|PSA2_HUMAN Proteasome subunit alpha type-2 OS 4 4PSMA3 P25788 >sp|P25788|PSA3_HUMAN Proteasome subunit alpha type-3 OS 5 9PSMA4 P25789 >sp|P25789|PSA4_HUMAN Proteasome subunit alpha type-4 OS 8 23PSMA5 P28066 >sp|P28066|PSA5_HUMAN Proteasome subunit alpha type-5 OS 6 12PSMA6 P60900 >sp|P60900|PSA6_HUMAN Proteasome subunit alpha type-6 OS 6 16PSMA7 O14818 >sp|O14818|PSA7_HUMAN Proteasome subunit alpha type-7 OS 7 10PSMA8 Q8TAA3 >sp|Q8TAA3|PSA7L_HUMAN Proteasome subunit alpha type-7-l 3 7PSMB1 P20618 >sp|P20618|PSB1_HUMAN Proteasome subunit beta type-1 OS= 6 15PSMB10 P40306 >sp|P40306|PSB10_HUMAN Proteasome subunit beta type-10 O 1 2PSMB2 P49721 >sp|P49721|PSB2_HUMAN Proteasome subunit beta type-2 OS= 1 10PSMB3 P49720 >sp|P49720|PSB3_HUMAN Proteasome subunit beta type-3 OS= 5 8PSMB4 P28070 >sp|P28070|PSB4_HUMAN Proteasome subunit beta type-4 OS= 4 4PSMB5 P28074 >sp|P28074|PSB5_HUMAN Proteasome subunit beta type-5 OS= 2 2PSMB6 P28072 >sp|P28072|PSB6_HUMAN Proteasome subunit beta type-6 OS= 3 6PSMB7 Q99436 >sp|Q99436|PSB7_HUMAN Proteasome subunit beta type-7 OS= 4 7PSMB8 P28062 >sp|P28062|PSB8_HUMAN Proteasome subunit beta type-8 OS= 1 3PSMC1 P62191 >sp|P62191|PRS4_HUMAN 26S protease regulatory subunit 4 O 7 12PSMC2 P35998 >sp|P35998|PRS7_HUMAN 26S protease regulatory subunit 7 O 8 12PSMC3 P17980 >sp|P17980|PRS6A_HUMAN 26S protease regulatory subunit 6 5 6PSMC4 P43686 >sp|P43686|PRS6B_HUMAN 26S protease regulatory subunit 6 1 1PSMC5 P62195 >sp|P62195|PRS8_HUMAN 26S protease regulatory subunit 8 O 4 6PSMC6 P62333 >sp|P62333|PRS10_HUMAN 26S protease regulatory subunit 1 4 5PSMD1 Q99460 >sp|Q99460|PSMD1_HUMAN 26S proteasome non-ATPase regulat 10 16PSMD11 O00231 >sp|O00231|PSD11_HUMAN 26S proteasome non-ATPase regulat 7 8PSMD12 O00232 >sp|O00232|PSD12_HUMAN 26S proteasome non-ATPase regulat 2 3PSMD13 Q9UNM6 >sp|Q9UNM6|PSD13_HUMAN 26S proteasome non-ATPase regulat 7 11PSMD14 O00487 >sp|O00487|PSDE_HUMAN 26S proteasome non-ATPase regulato 1 1PSMD2 Q13200 >sp|Q13200|PSMD2_HUMAN 26S proteasome non-ATPase regulat 5 10PSMD3 O43242 >sp|O43242|PSMD3_HUMAN 26S proteasome non-ATPase regulat 6 12PSMD5 Q16401 >sp|Q16401|PSMD5_HUMAN 26S proteasome non-ATPase regulat 3 3PSMD6 Q15008 >sp|Q15008|PSMD6_HUMAN 26S proteasome non-ATPase regulat 2 5PSMD7 P51665 >sp|P51665|PSMD7_HUMAN 26S proteasome non-ATPase regulat 2 2PSMD8 P48556 >sp|P48556|PSMD8_HUMAN 26S proteasome non-ATPase regulat 2 2PSMD9 O00233 >sp|O00233|PSMD9_HUMAN 26S proteasome non-ATPase regulat 2 3PSME1 Q06323 >sp|Q06323|PSME1_HUMAN Proteasome activator complex subu 13 36PSME2 Q9UL46 >sp|Q9UL46|PSME2_HUMAN Proteasome activator complex subu 4 8PTBP1 P26599 >sp|P26599|PTBP1_HUMAN Polypyrimidine tract-binding protei 3 10PTBP2 Q9UKA9 >sp|Q9UKA9|PTBP2_HUMAN Polypyrimidine tract-binding protei 1 1

PTGER2 P43116 >sp|P43116|PE2R2_HUMAN Prostaglandin E2 receptor EP2 sub 1 1PTGES O14684 >sp|O14684|PTGES_HUMAN Prostaglandin E synthase OS=Homo 1 1PTGES2 Q9H7Z7 >sp|Q9H7Z7|PGES2_HUMAN Prostaglandin E synthase 2 OS=Ho 1 1PTGES3 Q15185 >sp|Q15185|TEBP_HUMAN Prostaglandin E synthase 3 OS=Hom 1 4PTGFRN Q9P2B2 >sp|Q9P2B2|FPRP_HUMAN Prostaglandin F2 receptor negative 1 1PTGIS Q16647 >sp|Q16647|PTGIS_HUMAN Prostacyclin synthase OS=Homo sap 7 13PTGR1 Q14914 >sp|Q14914|PTGR1_HUMAN Prostaglandin reductase 1 OS=Hom 6 11PTGR2 Q8N8N7 >sp|Q8N8N7|PTGR2_HUMAN Prostaglandin reductase 2 OS=Hom 1 1PTMA P06454 >sp|P06454|PTMA_HUMAN Prothymosin alpha OS=Homo sapien 4 14PTMS P20962 >sp|P20962|PTMS_HUMAN Parathymosin OS=Homo sapiens GN 4 40

PTP4A1 Q93096 >sp|Q93096|TP4A1_HUMAN Protein tyrosine phosphatase type 1 2PTPLAD1 Q9P035 >sp|Q9P035|HACD3_HUMAN Very-long-chain (3R)-3-hydroxyacyl-[ 2 3

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PTPN11 Q06124 >sp|Q06124|PTN11_HUMAN Tyrosine-protein phosphatase non-re 3 5PTPRC P08575 >sp|P08575|PTPRC_HUMAN Receptor-type tyrosine-protein pho 1 2PTPRG P23470 >sp|P23470|PTPRG_HUMAN Receptor-type tyrosine-protein ph 1 1PTPRQ Q9UMZ3 >sp|Q9UMZ3|PTPRQ_HUMAN Phosphatidylinositol phosphatase 2 3PTPRS Q13332 >sp|Q13332|PTPRS_HUMAN Receptor-type tyrosine-protein pho 1 1PTRF Q6NZI2 >sp|Q6NZI2|PTRF_HUMAN Polymerase I and transcript release 30 503

PTTG1IP P53801 >sp|P53801|PTTG_HUMAN Pituitary tumor-transforming gene 1 pr 1 1PURA Q00577 >sp|Q00577|PURA_HUMAN Transcriptional activator protein Pu 5 7PURB Q96QR8 >sp|Q96QR8|PURB_HUMAN Transcriptional activator protein Pu 1 2

PYCARD Q9ULZ3 >sp|Q9ULZ3|ASC_HUMAN Apoptosis-associated speck-like prot 2 2PYCR1 P32322 >sp|P32322|P5CR1_HUMAN Pyrroline-5-carboxylate reductase 1 1 5PYGB P11216 >sp|P11216|PYGB_HUMAN Glycogen phosphorylase, brain form 19 51PYGL P06737 >sp|P06737|PYGL_HUMAN Glycogen phosphorylase, liver form 43 131PZP P20742 >sp|P20742|PZP_HUMAN Pregnancy zone protein OS=Homo sapi 1 2

QARS P47897 >sp|P47897|SYQ_HUMAN Glutamine--tRNA ligase OS=Homo sap 1 2QDPR P09417 >sp|P09417|DHPR_HUMAN Dihydropteridine reductase OS=Homo 8 37QIL1 Q5XKP0 >sp|Q5XKP0|QIL1_HUMAN Protein QIL1 OS=Homo sapiens GN=Q 1 1

RAB10 P61026 >sp|P61026|RAB10_HUMAN Ras-related protein Rab-10 OS=Hom 4 22RAB11A P62491 >sp|P62491|RB11A_HUMAN Ras-related protein Rab-11A OS=Ho 6 29RAB11B Q15907 >sp|Q15907|RB11B_HUMAN Ras-related protein Rab-11B OS=Ho 2 11RAB13 P51153 >sp|P51153|RAB13_HUMAN Ras-related protein Rab-13 OS=Hom 2 6RAB14 P61106 >sp|P61106|RAB14_HUMAN Ras-related protein Rab-14 OS=Hom 9 20RAB15 P59190 >sp|P59190|RAB15_HUMAN Ras-related protein Rab-15 OS=Hom 1 4RAB17 Q9H0T7 >sp|Q9H0T7|RAB17_HUMAN Ras-related protein Rab-17 OS=Hom 1 1RAB18 Q9NP72 >sp|Q9NP72|RAB18_HUMAN Ras-related protein Rab-18 OS=Hom 5 13RAB1A P62820 >sp|P62820|RAB1A_HUMAN Ras-related protein Rab-1A OS=Hom 9 49RAB1B Q9H0U4 >sp|Q9H0U4|RAB1B_HUMAN Ras-related protein Rab-1B OS=Ho 3 14RAB21 Q9UL25 >sp|Q9UL25|RAB21_HUMAN Ras-related protein Rab-21 OS=Hom 3 3

RAB22A Q9UL26 >sp|Q9UL26|RB22A_HUMAN Ras-related protein Rab-22A OS=H 1 1RAB2A P61019 >sp|P61019|RAB2A_HUMAN Ras-related protein Rab-2A OS=Hom 12 42RAB32 Q13637 >sp|Q13637|RAB32_HUMAN Ras-related protein Rab-32 OS=Hom 1 1RAB35 Q15286 >sp|Q15286|RAB35_HUMAN Ras-related protein Rab-35 OS=Hom 2 11RAB3D O95716 >sp|O95716|RAB3D_HUMAN Ras-related protein Rab-3D OS=Ho 1 6RAB5A P20339 >sp|P20339|RAB5A_HUMAN Ras-related protein Rab-5A OS=Hom 5 11RAB5B P61020 >sp|P61020|RAB5B_HUMAN Ras-related protein Rab-5B OS=Hom 5 8RAB5C P51148 >sp|P51148|RAB5C_HUMAN Ras-related protein Rab-5C OS=Ho 6 19RAB6A P20340 >sp|P20340|RAB6A_HUMAN Ras-related protein Rab-6A OS=Hom 2 3RAB6A P20340-2 >sp|P20340-2|RAB6A_HUMAN Isoform 2 of Ras-related protein 1 1RAB6B Q9NRW1 >sp|Q9NRW1|RAB6B_HUMAN Ras-related protein Rab-6B OS=Ho 1 1RAB7A P51149 >sp|P51149|RAB7A_HUMAN Ras-related protein Rab-7a OS=Hom 12 55RAB8A P61006 >sp|P61006|RAB8A_HUMAN Ras-related protein Rab-8A OS=Hom 2 5RAB8B Q92930 >sp|Q92930|RAB8B_HUMAN Ras-related protein Rab-8B OS=Ho 1 3

RABEP1 Q15276 >sp|Q15276|RABE1_HUMAN Rab GTPase-binding effector prote 1 1RABGGTA Q92696 >sp|Q92696|PGTA_HUMAN Geranylgeranyl transferase type-2 s 2 2

RAC1 P63000 >sp|P63000|RAC1_HUMAN Ras-related C3 botulinum toxin subst 8 34RAD23A P54725 >sp|P54725|RD23A_HUMAN UV excision repair protein RAD23 4 5RAD23B P54727 >sp|P54727|RD23B_HUMAN UV excision repair protein RAD23 12 57RAD50 Q92878 >sp|Q92878|RAD50_HUMAN DNA repair protein RAD50 OS=Homo 1 1RAI1 Q7Z5J4 >sp|Q7Z5J4|RAI1_HUMAN Retinoic acid-induced protein 1 OS=H 1 1RALA P11233 >sp|P11233|RALA_HUMAN Ras-related protein Ral-A OS=Homo 6 21RALB P11234 >sp|P11234|RALB_HUMAN Ras-related protein Ral-B OS=Homo 1 1RALY Q53GL6 >tr|Q53GL6|Q53GL6_HUMAN RNA binding protein (Autoantigenic, h 1 2RAN P62826 >sp|P62826|RAN_HUMAN GTP-binding nuclear protein Ran OS= 6 22

RANBP1 P43487 >sp|P43487|RANG_HUMAN Ran-specific GTPase-activating prot 2 2RANBP2 P49792 >sp|P49792|RBP2_HUMAN E3 SUMO-protein ligase RanBP2 OS 2 2RAP1A P62834 >sp|P62834|RAP1A_HUMAN Ras-related protein Rap-1A OS=Hom 12 56RAP1B P61224 >sp|P61224|RAP1B_HUMAN Ras-related protein Rap-1b OS=Hom 5 27RAP2A P10114 >sp|P10114|RAP2A_HUMAN Ras-related protein Rap-2a OS=Hom 3 6RAP2B P61225 >sp|P61225|RAP2B_HUMAN Ras-related protein Rap-2b OS=Hom 1 3

RAPGEF6 Q8TEU7 >sp|Q8TEU7|RPGF6_HUMAN Rap guanine nucleotide exchange f 1 1RARRES2 Q99969 >sp|Q99969|RARR2_HUMAN Retinoic acid receptor responder p 2 3

RARS P54136 >sp|P54136|SYRC_HUMAN Arginine--tRNA ligase, cytoplasmic 2 3RASIP1 Q5U651 >sp|Q5U651|RAIN_HUMAN Ras-interacting protein 1 OS=Homo s 1 3RBBP4 Q09028 >sp|Q09028|RBBP4_HUMAN Histone-binding protein RBBP4 OS 1 1

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RBBP9 O75884 >sp|O75884|RBBP9_HUMAN Putative hydrolase RBBP9 OS=Homo 1 1RBM Q13382 >tr|Q13382|Q13382_HUMAN RNA binding motif (Fragment) OS= 1 1RBP4 P02753 >sp|P02753|RET4_HUMAN Retinol-binding protein 4 OS=Homo s 5 11RBP7 Q96R05 >sp|Q96R05|RET7_HUMAN Retinoid-binding protein 7 OS=Homo 3 4RCN1 Q15293 >sp|Q15293|RCN1_HUMAN Reticulocalbin-1 OS=Homo sapiens 12 32RCN2 Q14257 >sp|Q14257|RCN2_HUMAN Reticulocalbin-2 OS=Homo sapiens 1 6RCN3 Q96D15 >sp|Q96D15|RCN3_HUMAN Reticulocalbin-3 OS=Homo sapiens 3 3RDH13 Q8NBN7 >sp|Q8NBN7|RDH13_HUMAN Retinol dehydrogenase 13 OS=Hom 2 3RDH5 Q92781 >sp|Q92781|RDH1_HUMAN 11-cis retinol dehydrogenase OS=Ho 4 13RDX P35241 >sp|P35241|RADI_HUMAN Radixin OS=Homo sapiens GN=RDX P 1 2

RECQL P46063 >sp|P46063|RECQ1_HUMAN ATP-dependent DNA helicase Q1 O 1 1REEP5 Q00765 >sp|Q00765|REEP5_HUMAN Receptor expression-enhancing pro 8 21RENBP P51606 >sp|P51606|RENBP_HUMAN N-acylglucosamine 2-epimerase OS 1 2REPS2 Q8NFH8 >sp|Q8NFH8|REPS2_HUMAN RalBP1-associated Eps domain-conta 1 1

RETSAT Q6NUM9 >sp|Q6NUM9|RETST_HUMAN All-trans-retinol 13,14-reductase 12 41REXO2 Q9Y3B8 >sp|Q9Y3B8|ORN_HUMAN Oligoribonuclease, mitochondrial OS 1 1RFTN1 Q14699 >sp|Q14699|RFTN1_HUMAN Raftlin OS=Homo sapiens GN=RFTN 8 14RGPD1 P0DJD0 >sp|P0DJD0|RGPD1_HUMAN RANBP2-like and GRIP domain-conta 1 1RGS10 O43665 >sp|O43665|RGS10_HUMAN Regulator of G-protein signaling 1 1 1RHOA P61586 >sp|P61586|RHOA_HUMAN Transforming protein RhoA OS=Homo 14 70RHOC P08134 >sp|P08134|RHOC_HUMAN Rho-related GTP-binding protein R 1 4RHOG P84095 >sp|P84095|RHOG_HUMAN Rho-related GTP-binding protein R 3 4RHOU Q7L0Q8 >sp|Q7L0Q8|RHOU_HUMAN Rho-related GTP-binding protein R 1 1RHPN2 Q8IUC4 >sp|Q8IUC4|RHPN2_HUMAN Rhophilin-2 OS=Homo sapiens GN= 1 2RMDN1 Q96DB5 >sp|Q96DB5|RMD1_HUMAN Regulator of microtubule dynamics p 1 2RMDN3 Q96TC7 >sp|Q96TC7|RMD3_HUMAN Regulator of microtubule dynamics p 1 3RNASE3 P12724 >sp|P12724|ECP_HUMAN Eosinophil cationic protein OS=Homo 1 1

RND1 Q92730 >sp|Q92730|RND1_HUMAN Rho-related GTP-binding protein Rh 1 1RNF170 Q96K19 >sp|Q96K19|RN170_HUMAN E3 ubiquitin-protein ligase RNF170 1 1RNF39 Q2L6J4 >tr|Q2L6J4|Q2L6J4_HUMAN Ring finger protein 39 OS=Homo sa 1 10RNH1 P13489 >sp|P13489|RINI_HUMAN Ribonuclease inhibitor OS=Homo sapi 20 98

RNPEP Q9H4A4 >sp|Q9H4A4|AMPB_HUMAN Aminopeptidase B OS=Homo sapien 7 18ROCK1 Q13464 >sp|Q13464|ROCK1_HUMAN Rho-associated protein kinase 1 O 2 3RORA P35398 >sp|P35398|RORA_HUMAN Nuclear receptor ROR-alpha OS=Hom 1 1RP2 O75695 >sp|O75695|XRP2_HUMAN Protein XRP2 OS=Homo sapiens GN= 1 2

RPA3 P35244 >sp|P35244|RFA3_HUMAN Replication protein A 14 kDa subunit 2 2RPE Q96AT9 >sp|Q96AT9|RPE_HUMAN Ribulose-phosphate 3-epimerase OS= 1 1

RPL10 P27635 >sp|P27635|RL10_HUMAN 60S ribosomal protein L10 OS=Homo 1 1RPL10A P62906 >sp|P62906|RL10A_HUMAN 60S ribosomal protein L10a OS=Hom 8 16RPL10L Q96L21 >sp|Q96L21|RL10L_HUMAN 60S ribosomal protein L10-like OS= 1 2RPL11 P62913 >sp|P62913|RL11_HUMAN 60S ribosomal protein L11 OS=Homo 3 8RPL12 P30050 >sp|P30050|RL12_HUMAN 60S ribosomal protein L12 OS=Homo 6 22RPL13 P26373 >sp|P26373|RL13_HUMAN 60S ribosomal protein L13 OS=Homo 7 17

RPL13A P40429 >sp|P40429|RL13A_HUMAN 60S ribosomal protein L13a OS=Hom 3 4RPL13AP3 Q6NVV1 >sp|Q6NVV1|R13P3_HUMAN Putative 60S ribosomal protein L13 1 2

RPL14 P50914 >sp|P50914|RL14_HUMAN 60S ribosomal protein L14 OS=Homo 3 15RPL15 P61313 >sp|P61313|RL15_HUMAN 60S ribosomal protein L15 OS=Homo 4 7RPL17 P18621 >sp|P18621|RL17_HUMAN 60S ribosomal protein L17 OS=Homo 4 13RPL18 Q07020 >sp|Q07020|RL18_HUMAN 60S ribosomal protein L18 OS=Homo 4 15

RPL18A Q02543 >sp|Q02543|RL18A_HUMAN 60S ribosomal protein L18a OS=Hom 3 7RPL19 P84098 >sp|P84098|RL19_HUMAN 60S ribosomal protein L19 OS=Homo 1 1RPL21 P46778 >sp|P46778|RL21_HUMAN 60S ribosomal protein L21 OS=Homo 1 1RPL22 P35268 >sp|P35268|RL22_HUMAN 60S ribosomal protein L22 OS=Homo 5 18RPL23 P62829 >sp|P62829|RL23_HUMAN 60S ribosomal protein L23 OS=Homo 3 7

RPL23A P62750 >sp|P62750|RL23A_HUMAN 60S ribosomal protein L23a OS=Hom 4 11RPL24 P83731 >sp|P83731|RL24_HUMAN 60S ribosomal protein L24 OS=Homo 2 9

RPL26L1 Q9UNX3 >sp|Q9UNX3|RL26L_HUMAN 60S ribosomal protein L26-like 1 O 3 6RPL27 P61353 >sp|P61353|RL27_HUMAN 60S ribosomal protein L27 OS=Homo 2 6

RPL27A P46776 >sp|P46776|RL27A_HUMAN 60S ribosomal protein L27a OS=Hom 3 6RPL28 P46779 >sp|P46779|RL28_HUMAN 60S ribosomal protein L28 OS=Homo 5 8RPL29 P47914 >sp|P47914|RL29_HUMAN 60S ribosomal protein L29 OS=Homo 1 5RPL3 P39023 >sp|P39023|RL3_HUMAN 60S ribosomal protein L3 OS=Homo sa 7 12

RPL30 P62888 >sp|P62888|RL30_HUMAN 60S ribosomal protein L30 OS=Homo 5 15RPL31 P62899 >sp|P62899|RL31_HUMAN 60S ribosomal protein L31 OS=Homo 2 2

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RPL32 P62910 >sp|P62910|RL32_HUMAN 60S ribosomal protein L32 OS=Homo 2 4RPL34 P49207 >sp|P49207|RL34_HUMAN 60S ribosomal protein L34 OS=Homo 2 5RPL35 P42766 >sp|P42766|RL35_HUMAN 60S ribosomal protein L35 OS=Homo 2 4

RPL35A P18077 >sp|P18077|RL35A_HUMAN 60S ribosomal protein L35a OS=Hom 2 2RPL36 Q9Y3U8 >sp|Q9Y3U8|RL36_HUMAN 60S ribosomal protein L36 OS=Homo 3 5RPL38 P63173 >sp|P63173|RL38_HUMAN 60S ribosomal protein L38 OS=Homo 2 2RPL3L Q92901 >sp|Q92901|RL3L_HUMAN 60S ribosomal protein L3-like OS=Ho 1 1RPL4 P36578 >sp|P36578|RL4_HUMAN 60S ribosomal protein L4 OS=Homo sa 12 27RPL5 P46777 >sp|P46777|RL5_HUMAN 60S ribosomal protein L5 OS=Homo sa 10 17RPL6 Q02878 >sp|Q02878|RL6_HUMAN 60S ribosomal protein L6 OS=Homo sa 7 26RPL7 P18124 >sp|P18124|RL7_HUMAN 60S ribosomal protein L7 OS=Homo sa 12 29

RPL7A P62424 >sp|P62424|RL7A_HUMAN 60S ribosomal protein L7a OS=Homo 7 12RPL8 P62917 >sp|P62917|RL8_HUMAN 60S ribosomal protein L8 OS=Homo sa 1 3RPL9 P32969 >sp|P32969|RL9_HUMAN 60S ribosomal protein L9 OS=Homo sa 3 13

RPLP0 P05388 >sp|P05388|RLA0_HUMAN 60S acidic ribosomal protein P0 OS= 2 16RPLP0P6 Q8NHW5 >sp|Q8NHW5|RLA0L_HUMAN 60S acidic ribosomal protein P0-li 5 14

RPLP1 P05386 >sp|P05386|RLA1_HUMAN 60S acidic ribosomal protein P1 OS= 2 22RPLP2 P05387 >sp|P05387|RLA2_HUMAN 60S acidic ribosomal protein P2 OS= 5 38RPN1 P04843 >sp|P04843|RPN1_HUMAN Dolichyl-diphosphooligosaccharide--pro 21 45RPN2 P04844 >sp|P04844|RPN2_HUMAN Dolichyl-diphosphooligosaccharide--pro 10 25RPS10 P46783 >sp|P46783|RS10_HUMAN 40S ribosomal protein S10 OS=Homo 4 14

RPS10P5 Q9NQ39 >sp|Q9NQ39|RS10L_HUMAN Putative 40S ribosomal protein S10 3 4RPS11 P62280 >sp|P62280|RS11_HUMAN 40S ribosomal protein S11 OS=Homo 5 11RPS12 P25398 >sp|P25398|RS12_HUMAN 40S ribosomal protein S12 OS=Homo 5 12RPS13 P62277 >sp|P62277|RS13_HUMAN 40S ribosomal protein S13 OS=Homo 7 19RPS14 P62263 >sp|P62263|RS14_HUMAN 40S ribosomal protein S14 OS=Homo 2 5RPS15 P62841 >sp|P62841|RS15_HUMAN 40S ribosomal protein S15 OS=Homo 1 1

RPS15A P62244 >sp|P62244|RS15A_HUMAN 40S ribosomal protein S15a OS=Hom 3 5RPS16 P62249 >sp|P62249|RS16_HUMAN 40S ribosomal protein S16 OS=Homo 4 8

RPS17L P0CW22 >sp|P0CW22|RS17L_HUMAN 40S ribosomal protein S17-like OS 4 9RPS18 P62269 >sp|P62269|RS18_HUMAN 40S ribosomal protein S18 OS=Homo 4 6RPS19 P39019 >sp|P39019|RS19_HUMAN 40S ribosomal protein S19 OS=Homo 8 19RPS2 P15880 >sp|P15880|RS2_HUMAN 40S ribosomal protein S2 OS=Homo sa 4 7

RPS20 P60866 >sp|P60866|RS20_HUMAN 40S ribosomal protein S20 OS=Homo 2 2RPS21 P63220 >sp|P63220|RS21_HUMAN 40S ribosomal protein S21 OS=Homo 1 3RPS23 P62266 >sp|P62266|RS23_HUMAN 40S ribosomal protein S23 OS=Homo 2 2RPS24 P62847 >sp|P62847|RS24_HUMAN 40S ribosomal protein S24 OS=Homo 3 9RPS25 P62851 >sp|P62851|RS25_HUMAN 40S ribosomal protein S25 OS=Homo 4 12RPS26 P62854 >sp|P62854|RS26_HUMAN 40S ribosomal protein S26 OS=Homo 1 1

RPS26P11 Q5JNZ5 >sp|Q5JNZ5|RS26L_HUMAN Putative 40S ribosomal protein S26- 2 3RPS28 P62857 >sp|P62857|RS28_HUMAN 40S ribosomal protein S28 OS=Homo 2 3RPS29 P62273 >sp|P62273|RS29_HUMAN 40S ribosomal protein S29 OS=Homo 1 2RPS3 P23396 >sp|P23396|RS3_HUMAN 40S ribosomal protein S3 OS=Homo sa 10 26

RPS3A P61247 >sp|P61247|RS3A_HUMAN 40S ribosomal protein S3a OS=Homo 11 29RPS4X P62701 >sp|P62701|RS4X_HUMAN 40S ribosomal protein S4, X isoform 8 20RPS5 P46782 >sp|P46782|RS5_HUMAN 40S ribosomal protein S5 OS=Homo sa 5 13RPS6 P62753 >sp|P62753|RS6_HUMAN 40S ribosomal protein S6 OS=Homo sa 2 3RPS7 P62081 >sp|P62081|RS7_HUMAN 40S ribosomal protein S7 OS=Homo sa 2 5RPS8 P62241 >sp|P62241|RS8_HUMAN 40S ribosomal protein S8 OS=Homo sa 6 11RPS9 P46781 >sp|P46781|RS9_HUMAN 40S ribosomal protein S9 OS=Homo sa 5 9RPSA P08865 >sp|P08865|RSSA_HUMAN 40S ribosomal protein SA OS=Homo 8 18RPSA Q96RS2 >tr|Q96RS2|Q96RS2_HUMAN 40S ribosomal protein SA OS=Hom 1 3RRAS P10301 >sp|P10301|RRAS_HUMAN Ras-related protein R-Ras OS=Homo 11 29

RRAS2 P62070 >sp|P62070|RRAS2_HUMAN Ras-related protein R-Ras2 OS=Ho 5 27RRBP1 Q9P2E9 >sp|Q9P2E9|RRBP1_HUMAN Ribosome-binding protein 1 OS=Ho 7 8

RSPH10B P0C881 >sp|P0C881|R10B1_HUMAN Radial spoke head 10 homolog B O 1 1RSU1 Q15404 >sp|Q15404|RSU1_HUMAN Ras suppressor protein 1 OS=Homo s 12 50RTCA O00442 >sp|O00442|RTCA_HUMAN RNA 3'-terminal phosphate cyclase 1 1RTCB Q9Y3I0 >sp|Q9Y3I0|RTCB_HUMAN tRNA-splicing ligase RtcB homolog 3 3RTN1 Q16799 >sp|Q16799|RTN1_HUMAN Reticulon-1 OS=Homo sapiens GN=R 1 2RTN3 O95197 >sp|O95197|RTN3_HUMAN Reticulon-3 OS=Homo sapiens GN=R 1 12RTN3 O95197-3 >sp|O95197-3|RTN3_HUMAN Isoform 3 of Reticulon-3 OS=Homo 1 2RTN4 Q9NQC3 >sp|Q9NQC3|RTN4_HUMAN Reticulon-4 OS=Homo sapiens GN=R 10 112RTN4 Q9NQC3-2 >sp|Q9NQC3-2|RTN4_HUMAN Isoform 2 of Reticulon-4 OS=Homo 1 2

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RTN4 Q9NQC3-3 >sp|Q9NQC3-3|RTN4_HUMAN Isoform 3 of Reticulon-4 OS=Homo 2 3RTN4 Q9NQC3-5 >sp|Q9NQC3-5|RTN4_HUMAN Isoform 5 of Reticulon-4 OS=Homo 1 2

RUVBL1 Q9Y265 >sp|Q9Y265|RUVB1_HUMAN RuvB-like 1 OS=Homo sapiens GN= 1 1S100A1 P23297 >sp|P23297|S10A1_HUMAN Protein S100-A1 OS=Homo sapiens 2 7S100A10 P60903 >sp|P60903|S10AA_HUMAN Protein S100-A10 OS=Homo sapiens 3 37S100A11 P31949 >sp|P31949|S10AB_HUMAN Protein S100-A11 OS=Homo sapiens 4 45S100A13 Q99584 >sp|Q99584|S10AD_HUMAN Protein S100-A13 OS=Homo sapien 6 23S100A16 Q96FQ6 >sp|Q96FQ6|S10AG_HUMAN Protein S100-A16 OS=Homo sapien 1 1S100A4 P26447 >sp|P26447|S10A4_HUMAN Protein S100-A4 OS=Homo sapiens 6 30S100A6 P06703 >sp|P06703|S10A6_HUMAN Protein S100-A6 OS=Homo sapiens 7 28S100A8 P05109 >sp|P05109|S10A8_HUMAN Protein S100-A8 OS=Homo sapiens 5 22S100A9 P06702 >sp|P06702|S10A9_HUMAN Protein S100-A9 OS=Homo sapiens 5 25S100B P04271 >sp|P04271|S100B_HUMAN Protein S100-B OS=Homo sapiens G 4 18SAA1 P0DJI8 >sp|P0DJI8|SAA1_HUMAN Serum amyloid A-1 protein OS=Homo 1 3SAA4 P35542 >sp|P35542|SAA4_HUMAN Serum amyloid A-4 protein OS=Homo 4 6

SACM1L Q9NTJ5 >sp|Q9NTJ5|SAC1_HUMAN Phosphatidylinositide phosphatase 3 8SAMHD1 Q9Y3Z3 >sp|Q9Y3Z3|SAMH1_HUMAN Deoxynucleoside triphosphate trip 4 7SAMM50 Q9Y512 >sp|Q9Y512|SAM50_HUMAN Sorting and assembly machinery co 2 3SAR1A Q9NR31 >sp|Q9NR31|SAR1A_HUMAN GTP-binding protein SAR1a OS=Ho 7 36SAR1B Q9Y6B6 >sp|Q9Y6B6|SAR1B_HUMAN GTP-binding protein SAR1b OS=Ho 1 4SARNP P82979 >sp|P82979|SARNP_HUMAN SAP domain-containing ribonucleop 2 2SARS P49591 >sp|P49591|SYSC_HUMAN Serine--tRNA ligase, cytoplasmic OS 4 9SBDS Q9Y3A5 >sp|Q9Y3A5|SBDS_HUMAN Ribosome maturation protein SBDS 7 16SBF1 O95248 >sp|O95248|MTMR5_HUMAN Myotubularin-related protein 5 OS= 1 2

SCAMP2 O15127 >sp|O15127|SCAM2_HUMAN Secretory carrier-associated membr 1 3SCAMP4 Q969E2 >sp|Q969E2|SCAM4_HUMAN Secretory carrier-associated membr 1 1SCARB2 Q14108 >sp|Q14108|SCRB2_HUMAN Lysosome membrane protein 2 OS= 3 8SCCPDH Q8NBX0 >sp|Q8NBX0|SCPDL_HUMAN Saccharopine dehydrogenase-like 2 6

SCD O00767 >sp|O00767|ACOD_HUMAN Acyl-CoA desaturase OS=Homo sapi 1 2SCFD1 Q8WVM8 >sp|Q8WVM8|SCFD1_HUMAN Sec1 family domain-containing pro 2 2SCP2 P22307 >sp|P22307|NLTP_HUMAN Non-specific lipid-transfer protein O 5 12

SCRN1 Q12765 >sp|Q12765|SCRN1_HUMAN Secernin-1 OS=Homo sapiens GN= 2 3SCRN2 Q96FV2 >sp|Q96FV2|SCRN2_HUMAN Secernin-2 OS=Homo sapiens GN= 4 12SDCBP O00560 >sp|O00560|SDCB1_HUMAN Syntenin-1 OS=Homo sapiens GN= 1 1SDHA P31040 >sp|P31040|SDHA_HUMAN Succinate dehydrogenase [ubiquinone] 7 18SDHB P21912 >sp|P21912|SDHB_HUMAN Succinate dehydrogenase [ubiquinone] 5 16SDPR O95810 >sp|O95810|SDPR_HUMAN Serum deprivation-response protein 16 101SDSL Q96GA7 >sp|Q96GA7|SDSL_HUMAN Serine dehydratase-like OS=Homo s 1 1

SEC11A P67812 >sp|P67812|SC11A_HUMAN Signal peptidase complex catalytic 4 6SEC22B O75396 >sp|O75396|SC22B_HUMAN Vesicle-trafficking protein SEC22b 10 23SEC24C P53992 >sp|P53992|SC24C_HUMAN Protein transport protein Sec24C O 1 3SEC31A O94979 >sp|O94979|SC31A_HUMAN Protein transport protein Sec31A O 4 8SEC61A1 P61619 >sp|P61619|S61A1_HUMAN Protein transport protein Sec61 subu 1 1

SEC62 Q99442 >sp|Q99442|SEC62_HUMAN Translocation protein SEC62 OS=Ho 1 1SECISBP2 Q96T21 >sp|Q96T21|SEBP2_HUMAN Selenocysteine insertion sequence-b 1 1SELENBP1 Q13228 >sp|Q13228|SBP1_HUMAN Selenium-binding protein 1 OS=Homo 33 244

SEMA6C Q24JR3 >tr|Q24JR3|Q24JR3_HUMAN SEMA6C protein OS=Homo sapien 1 2SEPT10 Q9P0V9 >sp|Q9P0V9|SEP10_HUMAN Septin-10 OS=Homo sapiens GN=SE 1 1SEPT11 Q9NVA2 >sp|Q9NVA2|SEP11_HUMAN Septin-11 OS=Homo sapiens GN=S 6 10SEPT14 Q6ZU15 >sp|Q6ZU15|SEP14_HUMAN Septin-14 OS=Homo sapiens GN=SE 1 2SEPT2 Q15019 >sp|Q15019|SEPT2_HUMAN Septin-2 OS=Homo sapiens GN=SEP 13 46SEPT7 Q16181 >sp|Q16181|SEPT7_HUMAN Septin-7 OS=Homo sapiens GN=SEP 12 34SEPT9 Q9UHD8 >sp|Q9UHD8|SEPT9_HUMAN Septin-9 OS=Homo sapiens GN=SE 5 7

SERBP1 Q8NC51 >sp|Q8NC51|PAIRB_HUMAN Plasminogen activator inhibitor 1 R 2 3SERPINA1 P01009 >sp|P01009|A1AT_HUMAN Alpha-1-antitrypsin OS=Homo sapien 37 626SERPINA2 P20848 >sp|P20848|A1ATR_HUMAN Putative alpha-1-antitrypsin-related 1 11SERPINA3 P01011 >sp|P01011|AACT_HUMAN Alpha-1-antichymotrypsin OS=Homo 14 61SERPINA4 P29622 >sp|P29622|KAIN_HUMAN Kallistatin OS=Homo sapiens GN=SER 3 3SERPINA5 P05154 >sp|P05154|IPSP_HUMAN Plasma serine protease inhibitor OS 1 2SERPINA6 P08185 >sp|P08185|CBG_HUMAN Corticosteroid-binding globulin OS=H 3 4SERPINA7 P05543 >sp|P05543|THBG_HUMAN Thyroxine-binding globulin OS=Homo 2 4SERPINB1 P30740 >sp|P30740|ILEU_HUMAN Leukocyte elastase inhibitor OS=Hom 1 1SERPINB6 P35237 >sp|P35237|SPB6_HUMAN Serpin B6 OS=Homo sapiens GN=SER 12 33SERPINC1 P01008 >sp|P01008|ANT3_HUMAN Antithrombin-III OS=Homo sapiens G 28 81

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SERPIND1 P05546 >sp|P05546|HEP2_HUMAN Heparin cofactor 2 OS=Homo sapien 7 20SERPINF1 P36955 >sp|P36955|PEDF_HUMAN Pigment epithelium-derived factor O 7 17SERPINF2 P08697 >sp|P08697|A2AP_HUMAN Alpha-2-antiplasmin OS=Homo sapie 9 30SERPING1 P05155 >sp|P05155|IC1_HUMAN Plasma protease C1 inhibitor OS=Homo 10 32SERPINH1 P50454 >sp|P50454|SERPH_HUMAN Serpin H1 OS=Homo sapiens GN=S 16 38

SET Q01105 >sp|Q01105|SET_HUMAN Protein SET OS=Homo sapiens GN=SE 3 7SF3A2 Q15428 >sp|Q15428|SF3A2_HUMAN Splicing factor 3A subunit 2 OS=Ho 1 1SF3B3 Q15393 >sp|Q15393|SF3B3_HUMAN Splicing factor 3B subunit 3 OS=Ho 1 1SFN P31947 >sp|P31947|1433S_HUMAN 14-3-3 protein sigma OS=Homo sapi 1 3

SFXN1 Q9H9B4 >sp|Q9H9B4|SFXN1_HUMAN Sideroflexin-1 OS=Homo sapiens G 1 1SFXN3 Q9BWM7 >sp|Q9BWM7|SFXN3_HUMAN Sideroflexin-3 OS=Homo sapiens 1 1SGCD Q92629 >sp|Q92629|SGCD_HUMAN Delta-sarcoglycan OS=Homo sapien 1 1SGCE O43556 >sp|O43556|SGCE_HUMAN Epsilon-sarcoglycan OS=Homo sapi 1 1SGCG Q13326 >sp|Q13326|SGCG_HUMAN Gamma-sarcoglycan OS=Homo sapi 1 1SGTA O43765 >sp|O43765|SGTA_HUMAN Small glutamine-rich tetratricopeptide 1 1

SH3BGRL O75368 >sp|O75368|SH3L1_HUMAN SH3 domain-binding glutamic acid-ri 6 15SH3BGRL2 Q9UJC5 >sp|Q9UJC5|SH3L2_HUMAN SH3 domain-binding glutamic acid-ri 1 1SH3BGRL3 Q9H299 >sp|Q9H299|SH3L3_HUMAN SH3 domain-binding glutamic acid-ri 5 16

SH3D19 Q5HYK7 >sp|Q5HYK7|SH319_HUMAN SH3 domain-containing protein 19 1 1SH3GL1 Q99961 >sp|Q99961|SH3G1_HUMAN Endophilin-A2 OS=Homo sapiens G 2 3

SH3GLB1 Q9Y371 >sp|Q9Y371|SHLB1_HUMAN Endophilin-B1 OS=Homo sapiens G 8 17SH3KBP1 Q96B97 >sp|Q96B97|SH3K1_HUMAN SH3 domain-containing kinase-bindi 2 2SHCBP1L Q9BZQ2 >sp|Q9BZQ2|SHP1L_HUMAN SHC SH2 domain-binding protein 1-l 1 1

SHMT1 P34896 >sp|P34896|GLYC_HUMAN Serine hydroxymethyltransferase, cy 2 4SIK1 P57059 >sp|P57059|SIK1_HUMAN Serine/threonine-protein kinase SIK1 1 4SIM2 H7BZX8 >tr|H7BZX8|H7BZX8_HUMAN Single-minded homolog 2 (Fragmen 1 1

SIPA1L1 O43166 >sp|O43166|SI1L1_HUMAN Signal-induced proliferation-associate 1 1SIRT2 Q8IXJ6 >sp|Q8IXJ6|SIR2_HUMAN NAD-dependent protein deacetylase si 1 1SKP1 P63208 >sp|P63208|SKP1_HUMAN S-phase kinase-associated protein 1 6 13

SLC14A2 Q15849 >sp|Q15849|UT2_HUMAN Urea transporter 2 OS=Homo sapiens 1 1SLC16A1 P53985 >sp|P53985|MOT1_HUMAN Monocarboxylate transporter 1 OS=H 1 1SLC16A7 O60669 >sp|O60669|MOT2_HUMAN Monocarboxylate transporter 2 OS=H 1 2SLC19A3 Q9BZV2 >sp|Q9BZV2|S19A3_HUMAN Thiamine transporter 2 OS=Homo sa 1 1SLC1A3 P43003 >sp|P43003|EAA1_HUMAN Excitatory amino acid transporter 1 1 1SLC1A5 Q15758 >sp|Q15758|AAAT_HUMAN Neutral amino acid transporter B(0) 1 1SLC25A1 P53007 >sp|P53007|TXTP_HUMAN Tricarboxylate transport protein, mit 6 11

SLC25A10 Q9UBX3 >sp|Q9UBX3|DIC_HUMAN Mitochondrial dicarboxylate carrier O 1 4SLC25A11 Q02978 >sp|Q02978|M2OM_HUMAN Mitochondrial 2-oxoglutarate/malate c 6 8SLC25A12 O75746 >sp|O75746|CMC1_HUMAN Calcium-binding mitochondrial carrier 2 3SLC25A20 O43772 >sp|O43772|MCAT_HUMAN Mitochondrial carnitine/acylcarnitine 2 3SLC25A24 Q6NUK1 >sp|Q6NUK1|SCMC1_HUMAN Calcium-binding mitochondrial carr 3 7SLC25A26 Q70HW3 >sp|Q70HW3|SAMC_HUMAN S-adenosylmethionine mitochondrial 1 4SLC25A3 Q00325 >sp|Q00325|MPCP_HUMAN Phosphate carrier protein, mitochond 11 30SLC25A3 Q00325-2 >sp|Q00325-2|MPCP_HUMAN Isoform B of Phosphate carrier prot 1 5SLC25A4 P12235 >sp|P12235|ADT1_HUMAN ADP/ATP translocase 1 OS=Homo sap 12 37SLC25A5 P05141 >sp|P05141|ADT2_HUMAN ADP/ATP translocase 2 OS=Homo sap 4 18SLC25A6 P12236 >sp|P12236|ADT3_HUMAN ADP/ATP translocase 3 OS=Homo sap 1 7SLC27A1 Q6PCB7 >sp|Q6PCB7|S27A1_HUMAN Long-chain fatty acid transport pro 1 2SLC27A3 Q5K4L6 >sp|Q5K4L6|S27A3_HUMAN Long-chain fatty acid transport prot 2 3SLC29A1 Q99808 >sp|Q99808|S29A1_HUMAN Equilibrative nucleoside transporte 1 1SLC2A1 P11166 >sp|P11166|GTR1_HUMAN Solute carrier family 2, facilitated gl 2 12SLC32A1 Q9H598 >sp|Q9H598|VIAAT_HUMAN Vesicular inhibitory amino acid tran 1 1SLC35A4 L0R6Q1 >tr|L0R6Q1|L0R6Q1_HUMAN Alternative protein SLC35A4 OS=H 2 2SLC35F6 Q8N357 >sp|Q8N357|S35F6_HUMAN Solute carrier family 35 member F6 1 2SLC39A4 Q6P5W5 >sp|Q6P5W5|S39A4_HUMAN Zinc transporter ZIP4 OS=Homo sa 1 1SLC39A7 Q92504 >sp|Q92504|S39A7_HUMAN Zinc transporter SLC39A7 OS=Homo 1 1SLC3A2 P08195 >sp|P08195|4F2_HUMAN 4F2 cell-surface antigen heavy chain 3 4SLC44A2 Q8IWA5 >sp|Q8IWA5|CTL2_HUMAN Choline transporter-like protein 2 O 3 3SLC4A1 P02730 >sp|P02730|B3AT_HUMAN Band 3 anion transport protein OS=H 20 99

SLC9A3R1 O14745 >sp|O14745|NHRF1_HUMAN Na(+)/H(+) exchange regulatory co 2 5SLC9A3R2 Q15599 >sp|Q15599|NHRF2_HUMAN Na(+)/H(+) exchange regulatory co 1 1SLITRK2 Q9H156 >sp|Q9H156|SLIK2_HUMAN SLIT and NTRK-like protein 2 OS=Ho 1 1

SLK Q9H2G2 >sp|Q9H2G2|SLK_HUMAN STE20-like serine/threonine-protein k 1 1SLX4 Q8IY92 >sp|Q8IY92|SLX4_HUMAN Structure-specific endonuclease subu 1 1

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SMARCD2 Q92925 >sp|Q92925|SMRD2_HUMAN SWI/SNF-related matrix-associated ac 1 1SMC3 Q9UQE7 >sp|Q9UQE7|SMC3_HUMAN Structural maintenance of chromoso 3 4SMG1 Q96Q15 >sp|Q96Q15|SMG1_HUMAN Serine/threonine-protein kinase SM 1 1

SMPDL3B Q92485 >sp|Q92485|ASM3B_HUMAN Acid sphingomyelinase-like phosph 1 1SMS P52788 >sp|P52788|SPSY_HUMAN Spermine synthase OS=Homo sapien 2 2

SNCA P37840 >sp|P37840|SYUA_HUMAN Alpha-synuclein OS=Homo sapiens 2 5SNCB Q16143 >sp|Q16143|SYUB_HUMAN Beta-synuclein OS=Homo sapiens G 2 4SNCG O76070 >sp|O76070|SYUG_HUMAN Gamma-synuclein OS=Homo sapiens 13 69SND1 Q7KZF4 >sp|Q7KZF4|SND1_HUMAN Staphylococcal nuclease domain-cont 8 10

SNRPA P09012 >sp|P09012|SNRPA_HUMAN U1 small nuclear ribonucleoprotein 1 1SNRPB2 P08579 >sp|P08579|RU2B_HUMAN U2 small nuclear ribonucleoprotein B 1 1SNRPD2 P62316 >sp|P62316|SMD2_HUMAN Small nuclear ribonucleoprotein Sm 1 1SNRPD3 P62318 >sp|P62318|SMD3_HUMAN Small nuclear ribonucleoprotein Sm 1 2SNRPE P62304 >sp|P62304|RUXE_HUMAN Small nuclear ribonucleoprotein E O 1 2SNTB2 Q13425 >sp|Q13425|SNTB2_HUMAN Beta-2-syntrophin OS=Homo sapien 3 4SNX1 Q13596 >sp|Q13596|SNX1_HUMAN Sorting nexin-1 OS=Homo sapiens G 7 15

SNX10 Q9Y5X0 >sp|Q9Y5X0|SNX10_HUMAN Sorting nexin-10 OS=Homo sapiens 1 1SNX12 Q9UMY4 >sp|Q9UMY4|SNX12_HUMAN Sorting nexin-12 OS=Homo sapien 1 2SNX13 Q86XC4 >tr|Q86XC4|Q86XC4_HUMAN Sorting nexin 13 OS=Homo sapien 1 4SNX2 O60749 >sp|O60749|SNX2_HUMAN Sorting nexin-2 OS=Homo sapiens G 4 4SNX3 O60493 >sp|O60493|SNX3_HUMAN Sorting nexin-3 OS=Homo sapiens G 5 11

SNX31 Q8N9S9 >sp|Q8N9S9|SNX31_HUMAN Sorting nexin-31 OS=Homo sapiens 1 1SNX32 Q86XE0 >sp|Q86XE0|SNX32_HUMAN Sorting nexin-32 OS=Homo sapiens 2 2SNX5 Q9Y5X3 >sp|Q9Y5X3|SNX5_HUMAN Sorting nexin-5 OS=Homo sapiens G 3 5SNX6 Q9UNH7 >sp|Q9UNH7|SNX6_HUMAN Sorting nexin-6 OS=Homo sapiens 11 20SNX9 Q9Y5X1 >sp|Q9Y5X1|SNX9_HUMAN Sorting nexin-9 OS=Homo sapiens G 2 2SOD1 P00441 >sp|P00441|SODC_HUMAN Superoxide dismutase [Cu-Zn] OS=H 7 42SOD2 P04179 >sp|P04179|SODM_HUMAN Superoxide dismutase [Mn], mitochon 10 65SOD3 P08294 >sp|P08294|SODE_HUMAN Extracellular superoxide dismutase 6 40

SORBS1 Q9BX66 >sp|Q9BX66|SRBS1_HUMAN Sorbin and SH3 domain-containing 23 109SORBS1 Q9BX66-4 >sp|Q9BX66-4|SRBS1_HUMAN Isoform 4 of Sorbin and SH3 domai 1 4

SORD Q00796 >sp|Q00796|DHSO_HUMAN Sorbitol dehydrogenase OS=Homo s 1 1SORT1 Q99523 >sp|Q99523|SORT_HUMAN Sortilin OS=Homo sapiens GN=SORT 1 2

SP7 Q8TDD2 >sp|Q8TDD2|SP7_HUMAN Transcription factor Sp7 OS=Homo sa 1 1SP-A2 Q16139 >tr|Q16139|Q16139_HUMAN SP-A2 delta (Fragment) OS=Homo s 1 4

SPACA4 Q8TDM5 >sp|Q8TDM5|SACA4_HUMAN Sperm acrosome membrane-associat 1 1SPARC P09486 >sp|P09486|SPRC_HUMAN SPARC OS=Homo sapiens GN=SPAR 6 19

SPARCL1 Q14515 >sp|Q14515|SPRL1_HUMAN SPARC-like protein 1 OS=Homo sap 1 1SPCS2 Q15005 >sp|Q15005|SPCS2_HUMAN Signal peptidase complex subunit 1 1SPEG Q15772 >sp|Q15772|SPEG_HUMAN Striated muscle preferentially expres 1 1SPG11 Q96JI7 >sp|Q96JI7|SPTCS_HUMAN Spatacsin OS=Homo sapiens GN=SP 1 1SPG7 Q9UQ90 >sp|Q9UQ90|SPG7_HUMAN Paraplegin OS=Homo sapiens GN=S 1 1

SPON1 Q9HCB6 >sp|Q9HCB6|SPON1_HUMAN Spondin-1 OS=Homo sapiens GN= 1 1SPR P35270 >sp|P35270|SPRE_HUMAN Sepiapterin reductase OS=Homo sap 6 12

SPTA1 P02549 >sp|P02549|SPTA1_HUMAN Spectrin alpha chain, erythrocytic 11 19SPTAN1 Q13813 >sp|Q13813|SPTN1_HUMAN Spectrin alpha chain, non-erythrocy 163 638SPTAN1 Q13813-3 >sp|Q13813-3|SPTN1_HUMAN Isoform 3 of Spectrin alpha chain, 1 2

SPTB P11277 >sp|P11277|SPTB1_HUMAN Spectrin beta chain, erythrocytic O 18 32SPTBN1 Q01082 >sp|Q01082|SPTB2_HUMAN Spectrin beta chain, non-erythrocyt 106 427SPTBN4 Q9H254 >sp|Q9H254|SPTN4_HUMAN Spectrin beta chain, non-erythrocyt 1 1SQRDL Q9Y6N5 >sp|Q9Y6N5|SQRD_HUMAN Sulfide:quinone oxidoreductase, mit 5 6

SRI P30626 >sp|P30626|SORCN_HUMAN Sorcin OS=Homo sapiens GN=SRI P 5 5SRM P19623 >sp|P19623|SPEE_HUMAN Spermidine synthase OS=Homo sapi 1 1

SRP54 P61011 >sp|P61011|SRP54_HUMAN Signal recognition particle 54 kDa p 2 2SRP68 Q9UHB9 >sp|Q9UHB9|SRP68_HUMAN Signal recognition particle subuni 1 1SRP9 P49458 >sp|P49458|SRP09_HUMAN Signal recognition particle 9 kDa pr 1 1

SRPRB Q9Y5M8 >sp|Q9Y5M8|SRPRB_HUMAN Signal recognition particle recepto 1 1SRRM4 A7MD48 >sp|A7MD48|SRRM4_HUMAN Serine/arginine repetitive matrix p 1 3SRSF2 Q01130 >sp|Q01130|SRSF2_HUMAN Serine/arginine-rich splicing factor 1 1

SSB P05455 >sp|P05455|LA_HUMAN Lupus La protein OS=Homo sapiens GN= 5 11SSBP1 Q04837 >sp|Q04837|SSBP_HUMAN Single-stranded DNA-binding protein, 3 7SSR1 P43307 >sp|P43307|SSRA_HUMAN Translocon-associated protein subuni 2 5SSR4 P51571 >sp|P51571|SSRD_HUMAN Translocon-associated protein subuni 2 6ST13 P50502 >sp|P50502|F10A1_HUMAN Hsc70-interacting protein OS=Homo 9 33

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ST3GAL6 F8WC98 >tr|F8WC98|F8WC98_HUMAN Type 2 lactosamine alpha-2,3-sialy 1 1STAT1 P42224 >sp|P42224|STAT1_HUMAN Signal transducer and activator of tr 3 3STAT3 P40763 >sp|P40763|STAT3_HUMAN Signal transducer and activator of tr 3 3

STAT5A P42229 >sp|P42229|STA5A_HUMAN Signal transducer and activator of t 3 4STAT6 P42226 >sp|P42226|STAT6_HUMAN Signal transducer and activator of tr 2 2

STEAP4 Q687X5 >sp|Q687X5|STEA4_HUMAN Metalloreductase STEAP4 OS=Homo 1 3STIP1 P31948 >sp|P31948|STIP1_HUMAN Stress-induced-phosphoprotein 1 OS 12 38STK10 O94804 >sp|O94804|STK10_HUMAN Serine/threonine-protein kinase 10 1 1STMN1 P16949 >sp|P16949|STMN1_HUMAN Stathmin OS=Homo sapiens GN=ST 4 4STOM P27105 >sp|P27105|STOM_HUMAN Erythrocyte band 7 integral membran 11 42

STOML2 Q9UJZ1 >sp|Q9UJZ1|STML2_HUMAN Stomatin-like protein 2, mitochondr 4 4STRA6 Q9BX79 >sp|Q9BX79|STRA6_HUMAN Stimulated by retinoic acid gene 6 1 1STRAP Q9Y3F4 >sp|Q9Y3F4|STRAP_HUMAN Serine-threonine kinase receptor-as 3 5STT3A P46977 >sp|P46977|STT3A_HUMAN Dolichyl-diphosphooligosaccharide--p 3 6STT3B Q8TCJ2 >sp|Q8TCJ2|STT3B_HUMAN Dolichyl-diphosphooligosaccharide--p 2 2STX11 O75558 >sp|O75558|STX11_HUMAN Syntaxin-11 OS=Homo sapiens GN= 1 2STX12 Q86Y82 >sp|Q86Y82|STX12_HUMAN Syntaxin-12 OS=Homo sapiens GN= 4 5STX7 O15400 >sp|O15400|STX7_HUMAN Syntaxin-7 OS=Homo sapiens GN=ST 4 5

STXBP1 P61764 >sp|P61764|STXB1_HUMAN Syntaxin-binding protein 1 OS=Hom 3 5STXBP3 O00186 >sp|O00186|STXB3_HUMAN Syntaxin-binding protein 3 OS=Hom 2 2

SUB1 P53999 >sp|P53999|TCP4_HUMAN Activated RNA polymerase II transcrip 1 1SUCLA2 Q9P2R7 >sp|Q9P2R7|SUCB1_HUMAN Succinyl-CoA ligase [ADP-forming] s 7 10SUCLG1 P53597 >sp|P53597|SUCA_HUMAN Succinyl-CoA ligase [ADP/GDP-forming 5 7SUCLG2 Q96I99 >sp|Q96I99|SUCB2_HUMAN Succinyl-CoA ligase [GDP-forming] su 12 20SULT1A1 P50225 >sp|P50225|ST1A1_HUMAN Sulfotransferase 1A1 OS=Homo sap 9 15SULT1A3 P50224 >sp|P50224|ST1A3_HUMAN Sulfotransferase 1A3/1A4 OS=Homo 3 5SUMO2 P61956 >sp|P61956|SUMO2_HUMAN Small ubiquitin-related modifier 2 1 3SUN2 Q9UH99 >sp|Q9UH99|SUN2_HUMAN SUN domain-containing protein 2 O 1 1

SURF4 O15260 >sp|O15260|SURF4_HUMAN Surfeit locus protein 4 OS=Homo sa 2 8SWAP70 Q9UH65 >sp|Q9UH65|SWP70_HUMAN Switch-associated protein 70 OS= 1 1SYNCRIP O60506 >sp|O60506|HNRPQ_HUMAN Heterogeneous nuclear ribonucleop 6 9

SYNM O15061 >sp|O15061|SYNEM_HUMAN Synemin OS=Homo sapiens GN=SY 14 20SYNPO2 Q9UMS6 >sp|Q9UMS6|SYNP2_HUMAN Synaptopodin-2 OS=Homo sapiens 1 1SYPL1 Q16563 >sp|Q16563|SYPL1_HUMAN Synaptophysin-like protein 1 OS=Ho 1 8TAAR1 Q96RJ0 >sp|Q96RJ0|TAAR1_HUMAN Trace amine-associated receptor 1 2 2TACC2 O95359 >sp|O95359|TACC2_HUMAN Transforming acidic coiled-coil-cont 1 1TAGLN Q01995 >sp|Q01995|TAGL_HUMAN Transgelin OS=Homo sapiens GN=TA 18 103

TAGLN2 P37802 >sp|P37802|TAGL2_HUMAN Transgelin-2 OS=Homo sapiens GN 13 72TAGLN3 Q9UI15 >sp|Q9UI15|TAGL3_HUMAN Transgelin-3 OS=Homo sapiens GN 2 5TALDO1 P37837 >sp|P37837|TALDO_HUMAN Transaldolase OS=Homo sapiens G 15 38TAPBP O15533 >sp|O15533|TPSN_HUMAN Tapasin OS=Homo sapiens GN=TAPB 1 1

TARDBP Q13148 >sp|Q13148|TADBP_HUMAN TAR DNA-binding protein 43 OS=Ho 1 2TARS P26639 >sp|P26639|SYTC_HUMAN Threonine--tRNA ligase, cytoplasmic 1 2

TAX1BP3 O14907 >sp|O14907|TX1B3_HUMAN Tax1-binding protein 3 OS=Homo sa 1 1TBC1D15 Q8TC07-2 >sp|Q8TC07-2|TBC15_HUMAN Isoform 2 of TBC1 domain family 1 2TBC1D24 Q9ULP9 >sp|Q9ULP9|TBC24_HUMAN TBC1 domain family member 24 OS 2 3

TBCA O75347 >sp|O75347|TBCA_HUMAN Tubulin-specific chaperone A OS=Ho 2 6TBCB Q99426 >sp|Q99426|TBCB_HUMAN Tubulin-folding cofactor B OS=Homo 2 3TBCD Q9BTW9 >sp|Q9BTW9|TBCD_HUMAN Tubulin-specific chaperone D OS=H 1 1

TCEAL3 Q969E4 >sp|Q969E4|TCAL3_HUMAN Transcription elongation factor A pr 4 7TCEB2 Q15370 >sp|Q15370|ELOB_HUMAN Transcription elongation factor B pol 2 4

TCHHL1 Q5QJ38 >sp|Q5QJ38|TCHL1_HUMAN Trichohyalin-like protein 1 OS=Hom 1 1TCP1 F5GZ03 >tr|F5GZ03|F5GZ03_HUMAN T-complex protein 1 subunit alpha 1 1TCP1 P17987 >sp|P17987|TCPA_HUMAN T-complex protein 1 subunit alpha O 18 42TECR Q9NZ01 >sp|Q9NZ01|TECR_HUMAN Very-long-chain enoyl-CoA reductas 1 3TENC1 Q63HR2 >sp|Q63HR2|TENC1_HUMAN Tensin-like C1 domain-containing 1 3TENM1 Q9UKZ4 >sp|Q9UKZ4|TEN1_HUMAN Teneurin-1 OS=Homo sapiens GN=T 1 1

TES Q9UGI8 >sp|Q9UGI8|TES_HUMAN Testin OS=Homo sapiens GN=TES PE= 1 1TET3 O43151 >sp|O43151|TET3_HUMAN Methylcytosine dioxygenase TET3 OS 1 1

TEX11 Q8IYF3 >sp|Q8IYF3|TEX11_HUMAN Testis-expressed sequence 11 prote 1 3TF B4DHZ6 >tr|B4DHZ6|B4DHZ6_HUMAN Transferrin, isoform CRA_c OS=Ho 1 23TF P02787 >sp|P02787|TRFE_HUMAN Serotransferrin OS=Homo sapiens GN 65 868

TFAM Q00059 >sp|Q00059|TFAM_HUMAN Transcription factor A, mitochondria 1 1TFG Q92734 >sp|Q92734|TFG_HUMAN Protein TFG OS=Homo sapiens GN=TF 1 1

Page 37: [XLS]media.nature.com · Web viewSupp-Table S2B Supp-Table S2A Gene name UniProt accession Fasta protein description Unique peptides Spectral counts A1BG P04217 >sp|P04217|A1BG_HUMAN

TFRC P02786 >sp|P02786|TFR1_HUMAN Transferrin receptor protein 1 OS=Ho 1 1TGFB1I1 O43294 >sp|O43294|TGFI1_HUMAN Transforming growth factor beta-1-ind 2 3TGFBI Q15582 >sp|Q15582|BGH3_HUMAN Transforming growth factor-beta-induc 3 4TGM2 P21980 >sp|P21980|TGM2_HUMAN Protein-glutamine gamma-glutamyltra 2 2

TGOLN2 O43493 >sp|O43493|TGON2_HUMAN Trans-Golgi network integral membr 1 1THBS1 P07996 >sp|P07996|TSP1_HUMAN Thrombospondin-1 OS=Homo sapiens 4 8THEM6 Q8WUY1 >sp|Q8WUY1|THEM6_HUMAN Protein THEM6 OS=Homo sapiens 2 2THOC3 Q96J01 >sp|Q96J01|THOC3_HUMAN THO complex subunit 3 OS=Homo s 1 3THY1 P04216 >sp|P04216|THY1_HUMAN Thy-1 membrane glycoprotein OS=Ho 3 11

TIMM10 P62072 >sp|P62072|TIM10_HUMAN Mitochondrial import inner membrane 1 1TIMM13 Q9Y5L4 >sp|Q9Y5L4|TIM13_HUMAN Mitochondrial import inner membrane 1 1TIMP1 P01033 >sp|P01033|TIMP1_HUMAN Metalloproteinase inhibitor 1 OS=Ho 1 2TJP1 Q07157 >sp|Q07157|ZO1_HUMAN Tight junction protein ZO-1 OS=Homo 2 2TJP2 Q9UDY2 >sp|Q9UDY2|ZO2_HUMAN Tight junction protein ZO-2 OS=Homo 1 1TKT P29401 >sp|P29401|TKT_HUMAN Transketolase OS=Homo sapiens GN=T 34 208TLK2 D3DU05 >tr|D3DU05|D3DU05_HUMAN Tousled-like kinase 2, isoform CR 1 1TLN1 Q9Y490 >sp|Q9Y490|TLN1_HUMAN Talin-1 OS=Homo sapiens GN=TLN1 107 397TLN2 Q9Y4G6 >sp|Q9Y4G6|TLN2_HUMAN Talin-2 OS=Homo sapiens GN=TLN2 58 143

TMBIM6 P55061 >sp|P55061|BI1_HUMAN Bax inhibitor 1 OS=Homo sapiens GN=T 1 1TMCO1 Q9UM00 >sp|Q9UM00|TMCO1_HUMAN Transmembrane and coiled-coil doma 1 1TMED10 P49755 >sp|P49755|TMEDA_HUMAN Transmembrane emp24 domain-contai 5 24TMED4 Q7Z7H5 >sp|Q7Z7H5|TMED4_HUMAN Transmembrane emp24 domain-conta 2 6TMED7 Q9Y3B3 >sp|Q9Y3B3|TMED7_HUMAN Transmembrane emp24 domain-conta 2 2TMED9 Q9BVK6 >sp|Q9BVK6|TMED9_HUMAN Transmembrane emp24 domain-conta 3 4

TMEM109 Q9BVC6 >sp|Q9BVC6|TM109_HUMAN Transmembrane protein 109 OS=Ho 2 14TMEM119 Q4V9L6 >sp|Q4V9L6|TM119_HUMAN Transmembrane protein 119 OS=Ho 2 3

TMEM126A Q9H061 >sp|Q9H061|T126A_HUMAN Transmembrane protein 126A OS=H 1 1TMEM205 Q6UW68 >sp|Q6UW68|TM205_HUMAN Transmembrane protein 205 OS=Ho 1 1TMEM245 Q9H330 >sp|Q9H330|TM245_HUMAN Transmembrane protein 245 OS=Ho 2 4TMEM245 Q9H330-2 >sp|Q9H330-2|TM245_HUMAN Isoform 2 of Transmembrane prot 1 1TMEM33 P57088 >sp|P57088|TMM33_HUMAN Transmembrane protein 33 OS=Hom 1 7TMEM43 Q9BTV4 >sp|Q9BTV4|TMM43_HUMAN Transmembrane protein 43 OS=Hom 10 15TMOD1 P28289 >sp|P28289|TMOD1_HUMAN Tropomodulin-1 OS=Homo sapiens 1 1TMOD3 Q9NYL9 >sp|Q9NYL9|TMOD3_HUMAN Tropomodulin-3 OS=Homo sapiens 2 2TMPO P42166 >sp|P42166|LAP2A_HUMAN Lamina-associated polypeptide 2, is 2 4TMPO P42167 >sp|P42167|LAP2B_HUMAN Lamina-associated polypeptide 2, i 1 1

TMSB10 P63313 >sp|P63313|TYB10_HUMAN Thymosin beta-10 OS=Homo sapien 2 9TMSB4X P62328 >sp|P62328|TYB4_HUMAN Thymosin beta-4 OS=Homo sapiens 5 28TMSB4X Q0P5P4 >tr|Q0P5P4|Q0P5P4_HUMAN TMSB4X protein (Fragment) OS=H 1 2

TMX1 Q9H3N1 >sp|Q9H3N1|TMX1_HUMAN Thioredoxin-related transmembrane p 2 2TMX2 Q9Y320 >sp|Q9Y320|TMX2_HUMAN Thioredoxin-related transmembrane p 1 1TMX4 Q9H1E5 >sp|Q9H1E5|TMX4_HUMAN Thioredoxin-related transmembrane p 1 2

TNFAIP2 Q03169 >sp|Q03169|TNAP2_HUMAN Tumor necrosis factor alpha-induced 2 3TNFRSF10B O14763 >sp|O14763|TR10B_HUMAN Tumor necrosis factor receptor sup 1 1

TNFRSF8 P28908 >sp|P28908|TNR8_HUMAN Tumor necrosis factor receptor supe 1 1TNFRSF9 Q07011 >sp|Q07011|TNR9_HUMAN Tumor necrosis factor receptor supe 1 4

TNKS O95271 >sp|O95271|TNKS1_HUMAN Tankyrase-1 OS=Homo sapiens GN 1 1TNKS1BP1 Q9C0C2 >sp|Q9C0C2|TB182_HUMAN 182 kDa tankyrase-1-binding prote 8 11

TNPO1 Q92973 >sp|Q92973|TNPO1_HUMAN Transportin-1 OS=Homo sapiens G 4 5TNRC6B Q9UPQ9 >sp|Q9UPQ9|TNR6B_HUMAN Trinucleotide repeat-containing ge 2 2

TNS1 B2RU35 >tr|B2RU35|B2RU35_HUMAN Tensin 1 OS=Homo sapiens GN=TN 1 2TNS1 Q9HBL0 >sp|Q9HBL0|TENS1_HUMAN Tensin-1 OS=Homo sapiens GN=TN 28 69TNXB P22105 >sp|P22105|TENX_HUMAN Tenascin-X OS=Homo sapiens GN=TN 1 2

TOLLIP Q9H0E2 >sp|Q9H0E2|TOLIP_HUMAN Toll-interacting protein OS=Homo sa 3 5TOMM20 Q15388 >sp|Q15388|TOM20_HUMAN Mitochondrial import receptor subu 1 1TOMM22 Q9NS69 >sp|Q9NS69|TOM22_HUMAN Mitochondrial import receptor sub 1 3TOMM6 Q96B49 >sp|Q96B49|TOM6_HUMAN Mitochondrial import receptor subun 2 3

TOMM70A O94826 >sp|O94826|TOM70_HUMAN Mitochondrial import receptor sub 6 8TOP2A P11388 >sp|P11388|TOP2A_HUMAN DNA topoisomerase 2-alpha OS=Hom 1 1TP53I3 Q53FA7 >sp|Q53FA7|QORX_HUMAN Quinone oxidoreductase PIG3 OS=Ho 1 1TPBGL P0DKB5 >sp|P0DKB5|TPBGL_HUMAN Trophoblast glycoprotein-like OS= 1 1

TPD52L2 O43399 >sp|O43399|TPD54_HUMAN Tumor protein D54 OS=Homo sapien 7 34TPI1 P60174 >sp|P60174|TPIS_HUMAN Triosephosphate isomerase OS=Homo 19 150

TPM1 P09493 >sp|P09493|TPM1_HUMAN Tropomyosin alpha-1 chain OS=Homo 20 113

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TPM1 P09493-2 >sp|P09493-2|TPM1_HUMAN Isoform 2 of Tropomyosin alpha-1 c 3 3TPM1 P09493-5 >sp|P09493-5|TPM1_HUMAN Isoform 5 of Tropomyosin alpha-1 c 1 3TPM1 P09493-6 >sp|P09493-6|TPM1_HUMAN Isoform 6 of Tropomyosin alpha-1 c 5 14TPM2 P07951 >sp|P07951|TPM2_HUMAN Tropomyosin beta chain OS=Homo sa 9 35TPM2 P07951-2 >sp|P07951-2|TPM2_HUMAN Isoform 2 of Tropomyosin beta cha 4 14TPM3 P06753-2 >sp|P06753-2|TPM3_HUMAN Isoform 2 of Tropomyosin alpha-3 c 19 83TPM3 Q5VU62 >tr|Q5VU62|Q5VU62_HUMAN TPM3 protein OS=Homo sapiens G 1 2TPM4 P67936 >sp|P67936|TPM4_HUMAN Tropomyosin alpha-4 chain OS=Homo 14 51TPP1 O14773 >sp|O14773|TPP1_HUMAN Tripeptidyl-peptidase 1 OS=Homo sap 4 16

TPPP3 Q9BW30 >sp|Q9BW30|TPPP3_HUMAN Tubulin polymerization-promoting pr 3 8TPR P12270 >sp|P12270|TPR_HUMAN Nucleoprotein TPR OS=Homo sapiens 2 2

TPSAB1 Q15661 >sp|Q15661|TRYB1_HUMAN Tryptase alpha/beta-1 OS=Homo sa 5 20TPSB2 Q6NZY1 >tr|Q6NZY1|Q6NZY1_HUMAN TPSB2 protein OS=Homo sapiens 1 2TPT1 P13693 >sp|P13693|TCTP_HUMAN Translationally-controlled tumor prot 8 16

TRAM1 Q15629 >sp|Q15629|TRAM1_HUMAN Translocating chain-associated mem 1 1TRAP1 Q12931 >sp|Q12931|TRAP1_HUMAN Heat shock protein 75 kDa, mitocho 1 9TRIM25 Q14258 >sp|Q14258|TRI25_HUMAN E3 ubiquitin/ISG15 ligase TRIM25 O 2 3TRIM28 Q13263 >sp|Q13263|TIF1B_HUMAN Transcription intermediary factor 1- 2 4TRIM54 Q9BYV2 >sp|Q9BYV2|TRI54_HUMAN Tripartite motif-containing protein 1 1TRIM60 Q495X7 >sp|Q495X7|TRI60_HUMAN Tripartite motif-containing protein 1 1TRIP10 Q15642 >sp|Q15642|CIP4_HUMAN Cdc42-interacting protein 4 OS=Homo 1 1TRMT13 Q9NUP7 >sp|Q9NUP7|TRM13_HUMAN tRNA:m(4)X modification enzyme T 1 1TRPV2 Q9Y5S1 >sp|Q9Y5S1|TRPV2_HUMAN Transient receptor potential cation 1 3

TSN Q15631 >sp|Q15631|TSN_HUMAN Translin OS=Homo sapiens GN=TSN P 3 7TSNAX Q99598 >sp|Q99598|TSNAX_HUMAN Translin-associated protein X OS= 1 1

TST Q16762 >sp|Q16762|THTR_HUMAN Thiosulfate sulfurtransferase OS=Ho 6 15TSTA3 Q13630 >sp|Q13630|FCL_HUMAN GDP-L-fucose synthase OS=Homo sapi 1 2TTLL12 Q14166 >sp|Q14166|TTL12_HUMAN Tubulin--tyrosine ligase-like protein 1 2

TTR P02766 >sp|P02766|TTHY_HUMAN Transthyretin OS=Homo sapiens GN= 6 30TUBA1A Q71U36 >sp|Q71U36|TBA1A_HUMAN Tubulin alpha-1A chain OS=Homo s 35 364TUBA1B P68363 >sp|P68363|TBA1B_HUMAN Tubulin alpha-1B chain OS=Homo s 2 19TUBA1C Q9BQE3 >sp|Q9BQE3|TBA1C_HUMAN Tubulin alpha-1C chain OS=Homo 1 2TUBA4A P68366 >sp|P68366|TBA4A_HUMAN Tubulin alpha-4A chain OS=Homo s 2 4TUBA4B Q9H853 >sp|Q9H853|TBA4B_HUMAN Putative tubulin-like protein alpha 1 1

TUBB P07437 >sp|P07437|TBB5_HUMAN Tubulin beta chain OS=Homo sapiens 6 62TUBB1 Q9H4B7 >sp|Q9H4B7|TBB1_HUMAN Tubulin beta-1 chain OS=Homo sapi 6 77

TUBB2A Q13885 >sp|Q13885|TBB2A_HUMAN Tubulin beta-2A chain OS=Homo sa 25 233TUBB2B Q9BVA1 >sp|Q9BVA1|TBB2B_HUMAN Tubulin beta-2B chain OS=Homo sa 1 1TUBB3 Q13509 >sp|Q13509|TBB3_HUMAN Tubulin beta-3 chain OS=Homo sapie 6 53

TUBB4A P04350 >sp|P04350|TBB4A_HUMAN Tubulin beta-4A chain OS=Homo sa 7 30TUBB4B P68371 >sp|P68371|TBB4B_HUMAN Tubulin beta-4B chain OS=Homo sa 1 11TUBB6 Q9BUF5 >sp|Q9BUF5|TBB6_HUMAN Tubulin beta-6 chain OS=Homo sapi 6 25TUBB8 Q3ZCM7 >sp|Q3ZCM7|TBB8_HUMAN Tubulin beta-8 chain OS=Homo sapi 1 1

TUBGCP3 Q96CW5 >sp|Q96CW5|GCP3_HUMAN Gamma-tubulin complex component 1 1TUFM P49411 >sp|P49411|EFTU_HUMAN Elongation factor Tu, mitochondrial 11 43TUSC5 A5PKU2 >tr|A5PKU2|A5PKU2_HUMAN TUSC5 protein OS=Homo sapiens 1 16TUSC5 Q8IXB3 >sp|Q8IXB3|TUSC5_HUMAN Tumor suppressor candidate 5 OS= 4 20TWF2 Q6IBS0 >sp|Q6IBS0|TWF2_HUMAN Twinfilin-2 OS=Homo sapiens GN=TW 4 8

TXLNG Q9NUQ3 >sp|Q9NUQ3|TXLNG_HUMAN Gamma-taxilin OS=Homo sapiens 1 1TXN P10599 >sp|P10599|THIO_HUMAN Thioredoxin OS=Homo sapiens GN=TX 7 24

TXNDC12 O95881 >sp|O95881|TXD12_HUMAN Thioredoxin domain-containing prot 1 1TXNDC17 Q9BRA2 >sp|Q9BRA2|TXD17_HUMAN Thioredoxin domain-containing pro 2 2TXNDC5 Q8NBS9 >sp|Q8NBS9|TXND5_HUMAN Thioredoxin domain-containing pro 12 42TXNL1 O43396 >sp|O43396|TXNL1_HUMAN Thioredoxin-like protein 1 OS=Homo 2 2

TXNRD1 Q16881 >sp|Q16881|TRXR1_HUMAN Thioredoxin reductase 1, cytoplas 1 1TXNRD2 Q9NNW7 >sp|Q9NNW7|TRXR2_HUMAN Thioredoxin reductase 2, mitochon 1 1

TYMP P19971 >sp|P19971|TYPH_HUMAN Thymidine phosphorylase OS=Homo s 7 16UBA1 P22314 >sp|P22314|UBA1_HUMAN Ubiquitin-like modifier-activating en 28 113UBA5 Q9GZZ9 >sp|Q9GZZ9|UBA5_HUMAN Ubiquitin-like modifier-activating e 3 3UBA52 P62987 >sp|P62987|RL40_HUMAN Ubiquitin-60S ribosomal protein L40 8 89UBA6 A0AVT1 >sp|A0AVT1|UBA6_HUMAN Ubiquitin-like modifier-activating e 1 1UBA7 P41226 >sp|P41226|UBA7_HUMAN Ubiquitin-like modifier-activating en 1 1

UBE2E2 Q96LR5 >sp|Q96LR5|UB2E2_HUMAN Ubiquitin-conjugating enzyme E2 E 1 2UBE2I P63279 >sp|P63279|UBC9_HUMAN SUMO-conjugating enzyme UBC9 OS= 1 2

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UBE2L3 P68036 >sp|P68036|UB2L3_HUMAN Ubiquitin-conjugating enzyme E2 L3 3 12UBE2N P61088 >sp|P61088|UBE2N_HUMAN Ubiquitin-conjugating enzyme E2 N 7 31UBE2V1 Q13404 >sp|Q13404|UB2V1_HUMAN Ubiquitin-conjugating enzyme E2 va 4 13UBQLN2 Q9UHD9 >sp|Q9UHD9|UBQL2_HUMAN Ubiquilin-2 OS=Homo sapiens GN= 1 1

UBR5 O95071 >sp|O95071|UBR5_HUMAN E3 ubiquitin-protein ligase UBR5 OS 1 1UBTF P17480 >sp|P17480|UBF1_HUMAN Nucleolar transcription factor 1 OS= 1 1

UBXN4 Q92575 >sp|Q92575|UBXN4_HUMAN UBX domain-containing protein 4 O 1 1UBXN6 Q9BZV1 >sp|Q9BZV1|UBXN6_HUMAN UBX domain-containing protein 6 1 2UCHL1 P09936 >sp|P09936|UCHL1_HUMAN Ubiquitin carboxyl-terminal hydrola 6 21UFC1 Q9Y3C8 >sp|Q9Y3C8|UFC1_HUMAN Ubiquitin-fold modifier-conjugating 1 1

UFD1L Q92890 >sp|Q92890|UFD1_HUMAN Ubiquitin fusion degradation protein 2 2UFL1 O94874 >sp|O94874|UFL1_HUMAN E3 UFM1-protein ligase 1 OS=Homo s 1 1UFM1 P61960 >sp|P61960|UFM1_HUMAN Ubiquitin-fold modifier 1 OS=Homo s 2 2UGDH O60701 >sp|O60701|UGDH_HUMAN UDP-glucose 6-dehydrogenase OS=H 4 4UGGT1 Q9NYU2 >sp|Q9NYU2|UGGG1_HUMAN UDP-glucose:glycoprotein glucosyl 9 17UGP2 Q16851 >sp|Q16851|UGPA_HUMAN UTP--glucose-1-phosphate uridylyltr 25 147

UQCR10 Q9UDW1 >sp|Q9UDW1|QCR9_HUMAN Cytochrome b-c1 complex subunit 1 2UQCRB P14927 >sp|P14927|QCR7_HUMAN Cytochrome b-c1 complex subunit 7 6 13

UQCRC1 P31930 >sp|P31930|QCR1_HUMAN Cytochrome b-c1 complex subunit 1, 13 41UQCRC2 P22695 >sp|P22695|QCR2_HUMAN Cytochrome b-c1 complex subunit 2, 15 61UQCRFS1 P47985 >sp|P47985|UCRI_HUMAN Cytochrome b-c1 complex subunit Rie 1 5

UQCRFS1P1 P0C7P4 >sp|P0C7P4|UCRIL_HUMAN Putative cytochrome b-c1 complex su 2 5UQCRH P07919 >sp|P07919|QCR6_HUMAN Cytochrome b-c1 complex subunit 6, 3 7UQCRQ O14949 >sp|O14949|QCR8_HUMAN Cytochrome b-c1 complex subunit 8 2 3USO1 O60763 >sp|O60763|USO1_HUMAN General vesicular transport factor p 7 12USP14 P54578 >sp|P54578|UBP14_HUMAN Ubiquitin carboxyl-terminal hydrola 6 13USP21 Q9UK80 >sp|Q9UK80|UBP21_HUMAN Ubiquitin carboxyl-terminal hydrola 1 1USP5 P45974 >sp|P45974|UBP5_HUMAN Ubiquitin carboxyl-terminal hydrolas 13 24USP8 P40818 >sp|P40818|UBP8_HUMAN Ubiquitin carboxyl-terminal hydrolas 1 1UTP18 Q9Y5J1 >sp|Q9Y5J1|UTP18_HUMAN U3 small nucleolar RNA-associated 1 1UTP20 O75691 >sp|O75691|UTP20_HUMAN Small subunit processome componen 1 1UTRN P46939 >sp|P46939|UTRO_HUMAN Utrophin OS=Homo sapiens GN=UTR 18 23

V<kappa>3 A0N5G5 >tr|A0N5G5|A0N5G5_HUMAN Rheumatoid factor D5 light chain ( 1 12V1-17 A2MYD0 >tr|A2MYD0|A2MYD0_HUMAN V1-17 protein (Fragment) OS=Homo 1 1V1-2 A2MYD6 >tr|A2MYD6|A2MYD6_HUMAN V1-2 protein (Fragment) OS=Homo 1 4

V1-22 Q5NV88 >tr|Q5NV88|Q5NV88_HUMAN V1-22 protein (Fragment) OS=Homo 1 1V1-3 Q5NV84 >tr|Q5NV84|Q5NV84_HUMAN V1-3 protein (Fragment) OS=Homo 1 1V4-2 Q5NV82 >tr|Q5NV82|Q5NV82_HUMAN V4-2 protein (Fragment) OS=Homo 1 1V5-2 A2MYC8 >tr|A2MYC8|A2MYC8_HUMAN V5-2 protein (Fragment) OS=Homo 1 2V5-6 Q5NV92 >tr|Q5NV92|Q5NV92_HUMAN V5-6 protein (Fragment) OS=Homo 1 2

VAMP2 P63027 >sp|P63027|VAMP2_HUMAN Vesicle-associated membrane prote 3 22VAMP3 Q15836 >sp|Q15836|VAMP3_HUMAN Vesicle-associated membrane prote 2 4VAMP5 O95183 >sp|O95183|VAMP5_HUMAN Vesicle-associated membrane prote 1 1VAPA Q9P0L0 >sp|Q9P0L0|VAPA_HUMAN Vesicle-associated membrane protein- 4 9VAPB O95292 >sp|O95292|VAPB_HUMAN Vesicle-associated membrane protein- 2 7VARS P26640 >sp|P26640|SYVC_HUMAN Valine--tRNA ligase OS=Homo sapie 3 4VASP P50552 >sp|P50552|VASP_HUMAN Vasodilator-stimulated phosphoprote 4 4VAT1 Q99536 >sp|Q99536|VAT1_HUMAN Synaptic vesicle membrane protein V 15 66VBP1 P61758 >sp|P61758|PFD3_HUMAN Prefoldin subunit 3 OS=Homo sapien 2 2

VCAM1 P19320 >sp|P19320|VCAM1_HUMAN Vascular cell adhesion protein 1 O 1 1VCL P18206 >sp|P18206|VINC_HUMAN Vinculin OS=Homo sapiens GN=VCL P 70 342VCP P55072 >sp|P55072|TERA_HUMAN Transitional endoplasmic reticulum 37 154

VDAC1 P21796 >sp|P21796|VDAC1_HUMAN Voltage-dependent anion-selective c 10 27VDAC2 P45880 >sp|P45880|VDAC2_HUMAN Voltage-dependent anion-selective c 11 62VDAC3 Q9Y277 >sp|Q9Y277|VDAC3_HUMAN Voltage-dependent anion-selective c 5 11

VH3 Q9Y509 >tr|Q9Y509|Q9Y509_HUMAN VH3 protein (Fragment) OS=Homo s 2 2VIM P08670 >sp|P08670|VIME_HUMAN Vimentin OS=Homo sapiens GN=VIM 61 1107

VKORC1 Q9BQB6 >sp|Q9BQB6|VKOR1_HUMAN Vitamin K epoxide reductase compl 1 1VKORC1L1 Q8N0U8 >sp|Q8N0U8|VKORL_HUMAN Vitamin K epoxide reductase complex 4 9

VL87-2 A2N2G6 >tr|A2N2G6|A2N2G6_HUMAN VL87-2 protein (Fragment) OS=Hom 1 1VPS26A O75436 >sp|O75436|VP26A_HUMAN Vacuolar protein sorting-associated 6 9VPS29 Q9UBQ0 >sp|Q9UBQ0|VPS29_HUMAN Vacuolar protein sorting-associated 6 8VPS35 Q96QK1 >sp|Q96QK1|VPS35_HUMAN Vacuolar protein sorting-associated 16 42VTI1B Q9UEU0 >sp|Q9UEU0|VTI1B_HUMAN Vesicle transport through interactio 1 5

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VTN P04004 >sp|P04004|VTNC_HUMAN Vitronectin OS=Homo sapiens GN=VT 8 44VWF P04275 >sp|P04275|VWF_HUMAN von Willebrand factor OS=Homo sapie 7 11

WARS P23381 >sp|P23381|SYWC_HUMAN Tryptophan--tRNA ligase, cytoplasm 12 35WASF2 Q9Y6W5 >sp|Q9Y6W5|WASF2_HUMAN Wiskott-Aldrich syndrome protein 1 1WDFY1 Q8IWB7 >sp|Q8IWB7|WDFY1_HUMAN WD repeat and FYVE domain-contain 1 1WDR1 O75083 >sp|O75083|WDR1_HUMAN WD repeat-containing protein 1 OS= 12 32WDR36 Q8NI36 >sp|Q8NI36|WDR36_HUMAN WD repeat-containing protein 36 O 1 2WDR44 Q5JSH3 >sp|Q5JSH3|WDR44_HUMAN WD repeat-containing protein 44 1 1WDR77 Q9BQA1 >sp|Q9BQA1|MEP50_HUMAN Methylosome protein 50 OS=Homo 1 1WFS1 O76024 >sp|O76024|WFS1_HUMAN Wolframin OS=Homo sapiens GN=WF 4 4WNK1 Q9H4A3 >sp|Q9H4A3|WNK1_HUMAN Serine/threonine-protein kinase W 1 1XPO1 O14980 >sp|O14980|XPO1_HUMAN Exportin-1 OS=Homo sapiens GN=XP 1 3XPO4 Q9C0E2 >sp|Q9C0E2|XPO4_HUMAN Exportin-4 OS=Homo sapiens GN=XP 1 1XPO7 Q9UIA9 >sp|Q9UIA9|XPO7_HUMAN Exportin-7 OS=Homo sapiens GN=XP 1 1

XRCC5 P13010 >sp|P13010|XRCC5_HUMAN X-ray repair cross-complementing p 15 28XRCC6 P12956 >sp|P12956|XRCC6_HUMAN X-ray repair cross-complementing p 15 25YAP1 P46937 >sp|P46937|YAP1_HUMAN Yorkie homolog OS=Homo sapiens G 2 2YBX1 P67809 >sp|P67809|YBOX1_HUMAN Nuclease-sensitive element-binding 4 16YBX3 P16989 >sp|P16989|YBOX3_HUMAN Y-box-binding protein 3 OS=Homo s 1 1YKT6 O15498 >sp|O15498|YKT6_HUMAN Synaptobrevin homolog YKT6 OS=Hom 2 2

YTHDF1 Q9BYJ9 >sp|Q9BYJ9|YTHD1_HUMAN YTH domain-containing family prot 1 1YWHAB P31946 >sp|P31946|1433B_HUMAN 14-3-3 protein beta/alpha OS=Homo 19 135YWHAE P62258 >sp|P62258|1433E_HUMAN 14-3-3 protein epsilon OS=Homo sa 19 121YWHAG P61981 >sp|P61981|1433G_HUMAN 14-3-3 protein gamma OS=Homo sa 13 111YWHAH Q04917 >sp|Q04917|1433F_HUMAN 14-3-3 protein eta OS=Homo sapie 7 18YWHAQ P27348 >sp|P27348|1433T_HUMAN 14-3-3 protein theta OS=Homo sapi 8 25YWHAZ P63104 >sp|P63104|1433Z_HUMAN 14-3-3 protein zeta/delta OS=Homo 13 118ZHX3 H0YLR4 >tr|H0YLR4|H0YLR4_HUMAN Zinc fingers and homeoboxes protei 1 1

ZMPSTE24 O75844 >sp|O75844|FACE1_HUMAN CAAX prenyl protease 1 homolog O 1 1ZMYM4 Q5VZL5 >sp|Q5VZL5|ZMYM4_HUMAN Zinc finger MYM-type protein 4 OS 1 1

ZMYND8 Q9ULU4 >sp|Q9ULU4|PKCB1_HUMAN Protein kinase C-binding protein 1 1ZNF268 Q14587 >sp|Q14587|ZN268_HUMAN Zinc finger protein 268 OS=Homo sa 2 166

ZNF518B Q9C0D4 >sp|Q9C0D4|Z518B_HUMAN Zinc finger protein 518B OS=Homo 1 1ZNF648 Q5T619 >sp|Q5T619|ZN648_HUMAN Zinc finger protein 648 OS=Homo sa 1 4ZNF812 P0C7V5 >sp|P0C7V5|ZN812_HUMAN Putative zinc finger protein 812 OS 1 1

ZSCAN21 G3V1M0 >tr|G3V1M0|G3V1M0_HUMAN Zinc finger and SCAN domain-conta 1 1ZYX Q15942 >sp|Q15942|ZYX_HUMAN Zyxin OS=Homo sapiens GN=ZYX PE=1 2 2

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Annotation Database Category Count % Fold enrichmentGOTERM_BP_FAT GO:0006414~translational elongation 80 3.53 0.00 5.57GOTERM_BP_FAT GO:0006091~generation of precursor metabolites and energy 138 6.09 0.00 3.10GOTERM_BP_FAT GO:0055114~oxidation reduction 211 9.31 0.00 2.32GOTERM_BP_FAT GO:0006412~translation 137 6.05 0.00 2.91GOTERM_BP_FAT GO:0045333~cellular respiration 57 2.52 0.00 4.13GOTERM_BP_FAT GO:0015980~energy derivation by oxidation of organic compounds 69 3.05 0.00 3.37GOTERM_BP_FAT GO:0046907~intracellular transport 180 7.94 0.00 1.93GOTERM_BP_FAT GO:0016044~membrane organization 122 5.38 0.00 2.25GOTERM_BP_FAT GO:0022900~electron transport chain 57 2.52 0.00 3.52GOTERM_BP_FAT GO:0016052~carbohydrate catabolic process 54 2.38 0.00 3.48GOTERM_BP_FAT GO:0006732~coenzyme metabolic process 66 2.91 0.00 3.03GOTERM_BP_FAT GO:0046164~alcohol catabolic process 45 1.99 0.00 3.91GOTERM_BP_FAT GO:0044275~cellular carbohydrate catabolic process 46 2.03 0.00 3.81GOTERM_BP_FAT GO:0006457~protein folding 71 3.13 0.00 2.82GOTERM_BP_FAT GO:0006007~glucose catabolic process 37 1.63 0.00 4.49GOTERM_BP_FAT GO:0051351~positive regulation of ligase activity 42 1.85 0.00 4.05GOTERM_BP_FAT GO:0051443~positive regulation of ubiquitin-protein ligase activity 41 1.81 0.00 4.12GOTERM_BP_FAT GO:0006006~glucose metabolic process 64 2.82 0.00 2.94GOTERM_BP_FAT GO:0007010~cytoskeleton organization 128 5.65 0.00 2.06GOTERM_BP_FAT GO:0051186~cofactor metabolic process 74 3.27 0.00 2.67GOTERM_BP_FAT GO:0046365~monosaccharide catabolic process 40 1.77 0.00 3.96GOTERM_BP_FAT GO:0051437~positive regulation of ubiquitin-protein ligase activity during mitoti 39 1.72 0.00 4.03GOTERM_BP_FAT GO:0051436~negative regulation of ubiquitin-protein ligase activity during mitot 38 1.68 0.00 4.11GOTERM_BP_FAT GO:0031145~anaphase-promoting complex-dependent proteasomal ubiquitin-de 38 1.68 0.00 4.11GOTERM_BP_FAT GO:0030029~actin filament-based process 84 3.71 0.00 2.45GOTERM_BP_FAT GO:0051248~negative regulation of protein metabolic process 71 3.13 0.00 2.67GOTERM_BP_FAT GO:0032269~negative regulation of cellular protein metabolic process 69 3.05 0.00 2.70GOTERM_BP_FAT GO:0051352~negative regulation of ligase activity 38 1.68 0.00 3.99GOTERM_BP_FAT GO:0051444~negative regulation of ubiquitin-protein ligase activity 38 1.68 0.00 3.99GOTERM_BP_FAT GO:0022904~respiratory electron transport chain 37 1.63 0.00 4.06GOTERM_BP_FAT GO:0031400~negative regulation of protein modification process 53 2.34 0.00 3.13GOTERM_BP_FAT GO:0031398~positive regulation of protein ubiquitination 43 1.90 0.00 3.60GOTERM_BP_FAT GO:0006119~oxidative phosphorylation 47 2.07 0.00 3.37GOTERM_BP_FAT GO:0051439~regulation of ubiquitin-protein ligase activity during mitotic cell cy 39 1.72 0.00 3.86GOTERM_BP_FAT GO:0051340~regulation of ligase activity 42 1.85 0.00 3.65GOTERM_BP_FAT GO:0030036~actin cytoskeleton organization 79 3.49 0.00 2.46GOTERM_BP_FAT GO:0010498~proteasomal protein catabolic process 48 2.12 0.00 3.31GOTERM_BP_FAT GO:0043161~proteasomal ubiquitin-dependent protein catabolic process 48 2.12 0.00 3.31GOTERM_BP_FAT GO:0019318~hexose metabolic process 71 3.13 0.00 2.60GOTERM_BP_FAT GO:0051438~regulation of ubiquitin-protein ligase activity 41 1.81 0.00 3.70GOTERM_BP_FAT GO:0019320~hexose catabolic process 38 1.68 0.00 3.87GOTERM_BP_FAT GO:0016192~vesicle-mediated transport 151 6.66 0.00 1.84GOTERM_BP_FAT GO:0005996~monosaccharide metabolic process 77 3.40 0.00 2.44GOTERM_BP_FAT GO:0002526~acute inflammatory response 46 2.03 0.00 3.30GOTERM_BP_FAT GO:0031397~negative regulation of protein ubiquitination 39 1.72 0.00 3.71GOTERM_BP_FAT GO:0006096~glycolysis 30 1.32 0.00 4.49GOTERM_BP_FAT GO:0009060~aerobic respiration 25 1.10 0.00 5.02GOTERM_BP_FAT GO:0015031~protein transport 181 7.99 0.00 1.67GOTERM_BP_FAT GO:0042773~ATP synthesis coupled electron transport 32 1.41 0.00 4.02GOTERM_BP_FAT GO:0042775~mitochondrial ATP synthesis coupled electron transport 32 1.41 0.00 4.02GOTERM_BP_FAT GO:0045184~establishment of protein localization 182 8.03 0.00 1.66GOTERM_BP_FAT GO:0008104~protein localization 202 8.91 0.00 1.61GOTERM_BP_FAT GO:0031396~regulation of protein ubiquitination 44 1.94 0.00 3.09GOTERM_BP_FAT GO:0006099~tricarboxylic acid cycle 19 0.84 0.00 5.81GOTERM_BP_FAT GO:0046356~acetyl-CoA catabolic process 19 0.84 0.00 5.81GOTERM_BP_FAT GO:0032268~regulation of cellular protein metabolic process 123 5.43 0.00 1.82GOTERM_BP_FAT GO:0006084~acetyl-CoA metabolic process 22 0.97 0.00 4.99GOTERM_BP_FAT GO:0051187~cofactor catabolic process 22 0.97 0.00 4.99GOTERM_BP_FAT GO:0009109~coenzyme catabolic process 20 0.88 0.00 5.41

Table S2B. GO enrichment analysis of the 2,525 VAT proteins identified. ‘Count’ represents the number of proteins within the corresponding categories. The percentage represents the proportion of gene-coded proteins in the corresponding GOBP. The magnitude of GOPB enrichment is measured by the corresponding fold enrichment, and p values indicate the significance level. Only GOBP terms with p < 0.05 are shown. Green cells correspond to GOBPs represented in Supplementary Fig. S1B.

p value

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GOTERM_BP_FAT GO:0065003~macromolecular complex assembly 158 6.97 0.00 1.67GOTERM_BP_FAT GO:0034622~cellular macromolecular complex assembly 91 4.02 0.00 2.01GOTERM_BP_FAT GO:0043933~macromolecular complex subunit organization 165 7.28 0.00 1.63GOTERM_BP_FAT GO:0043623~cellular protein complex assembly 57 2.52 0.00 2.47GOTERM_BP_FAT GO:0009820~alkaloid metabolic process 25 1.10 0.00 4.29GOTERM_BP_FAT GO:0006986~response to unfolded protein 34 1.50 0.00 3.37GOTERM_BP_FAT GO:0006769~nicotinamide metabolic process 24 1.06 0.00 4.22GOTERM_BP_FAT GO:0046496~nicotinamide nucleotide metabolic process 24 1.06 0.00 4.22GOTERM_BP_FAT GO:0045454~cell redox homeostasis 31 1.37 0.00 3.46GOTERM_BP_FAT GO:0007264~small GTPase mediated signal transduction 86 3.80 0.00 1.98GOTERM_BP_FAT GO:0034621~cellular macromolecular complex subunit organization 96 4.24 0.00 1.89GOTERM_BP_FAT GO:0048193~Golgi vesicle transport 48 2.12 0.00 2.58GOTERM_BP_FAT GO:0010035~response to inorganic substance 64 2.82 0.00 2.20GOTERM_BP_FAT GO:0006120~mitochondrial electron transport, NADH to ubiquinone 24 1.06 0.00 4.02GOTERM_BP_FAT GO:0019362~pyridine nucleotide metabolic process 24 1.06 0.00 4.02GOTERM_BP_FAT GO:0043603~cellular amide metabolic process 28 1.24 0.00 3.52GOTERM_BP_FAT GO:0007265~Ras protein signal transduction 40 1.77 0.00 2.68GOTERM_BP_FAT GO:0006886~intracellular protein transport 96 4.24 0.00 1.80GOTERM_BP_FAT GO:0051493~regulation of cytoskeleton organization 47 2.07 0.00 2.43GOTERM_BP_FAT GO:0006090~pyruvate metabolic process 23 1.02 0.00 3.85GOTERM_BP_FAT GO:0006979~response to oxidative stress 53 2.34 0.00 2.27GOTERM_BP_FAT GO:0034613~cellular protein localization 102 4.50 0.00 1.74GOTERM_BP_FAT GO:0010033~response to organic substance 158 6.97 0.00 1.54GOTERM_BP_FAT GO:0008064~regulation of actin polymerization or depolymerization 28 1.24 0.00 3.23GOTERM_BP_FAT GO:0070727~cellular macromolecule localization 102 4.50 0.00 1.73GOTERM_BP_FAT GO:0031399~regulation of protein modification process 79 3.49 0.00 1.88GOTERM_BP_FAT GO:0031401~positive regulation of protein modification process 57 2.52 0.00 2.14GOTERM_BP_FAT GO:0070271~protein complex biogenesis 118 5.21 0.00 1.64GOTERM_BP_FAT GO:0006461~protein complex assembly 118 5.21 0.00 1.64GOTERM_BP_FAT GO:0051789~response to protein stimulus 39 1.72 0.00 2.56GOTERM_BP_FAT GO:0006631~fatty acid metabolic process 59 2.60 0.00 2.10GOTERM_BP_FAT GO:0030832~regulation of actin filament length 28 1.24 0.00 3.12GOTERM_BP_FAT GO:0006733~oxidoreduction coenzyme metabolic process 25 1.10 0.00 3.38GOTERM_BP_FAT GO:0032270~positive regulation of cellular protein metabolic process 66 2.91 0.00 1.99GOTERM_BP_FAT GO:0051247~positive regulation of protein metabolic process 68 3.00 0.00 1.97GOTERM_BP_FAT GO:0006958~complement activation, classical pathway 18 0.79 0.00 4.36GOTERM_BP_FAT GO:0006956~complement activation 22 0.97 0.00 3.68GOTERM_BP_FAT GO:0010324~membrane invagination 63 2.78 0.00 2.01GOTERM_BP_FAT GO:0006897~endocytosis 63 2.78 0.00 2.01GOTERM_BP_FAT GO:0032271~regulation of protein polymerization 29 1.28 0.00 3.00GOTERM_BP_FAT GO:0006518~peptide metabolic process 25 1.10 0.00 3.32GOTERM_BP_FAT GO:0002541~activation of plasma proteins involved in acute inflammatory re 22 0.97 0.00 3.60GOTERM_BP_FAT GO:0044093~positive regulation of molecular function 131 5.78 0.00 1.57GOTERM_BP_FAT GO:0034637~cellular carbohydrate biosynthetic process 29 1.28 0.00 2.96GOTERM_BP_FAT GO:0043254~regulation of protein complex assembly 34 1.50 0.00 2.66GOTERM_BP_FAT GO:0046364~monosaccharide biosynthetic process 20 0.88 0.00 3.80GOTERM_BP_FAT GO:0046165~alcohol biosynthetic process 22 0.97 0.00 3.52GOTERM_BP_FAT GO:0002455~humoral immune response mediated by circulating immunoglobu 18 0.79 0.00 4.08GOTERM_BP_FAT GO:0043086~negative regulation of catalytic activity 73 3.22 0.00 1.85GOTERM_BP_FAT GO:0019748~secondary metabolic process 31 1.37 0.00 2.76GOTERM_BP_FAT GO:0006749~glutathione metabolic process 17 0.75 0.00 4.27GOTERM_BP_FAT GO:0006635~fatty acid beta-oxidation 17 0.75 0.00 4.27GOTERM_BP_FAT GO:0051129~negative regulation of cellular component organization 45 1.99 0.00 2.23GOTERM_BP_FAT GO:0030833~regulation of actin filament polymerization 24 1.06 0.00 3.12GOTERM_BP_FAT GO:0009611~response to wounding 118 5.21 0.00 1.57GOTERM_BP_FAT GO:0043085~positive regulation of catalytic activity 116 5.12 0.00 1.57GOTERM_BP_FAT GO:0043244~regulation of protein complex disassembly 23 1.02 0.00 3.17GOTERM_BP_FAT GO:0033043~regulation of organelle organization 59 2.60 0.00 1.91GOTERM_BP_FAT GO:0006739~NADP metabolic process 12 0.53 0.00 5.27GOTERM_BP_FAT GO:0051258~protein polymerization 22 0.97 0.00 3.16GOTERM_BP_FAT GO:0044092~negative regulation of molecular function 81 3.57 0.00 1.71GOTERM_BP_FAT GO:0007599~hemostasis 36 1.59 0.00 2.34GOTERM_BP_FAT GO:0043039~tRNA aminoacylation 21 0.93 0.00 3.21GOTERM_BP_FAT GO:0006418~tRNA aminoacylation for protein translation 21 0.93 0.00 3.21GOTERM_BP_FAT GO:0043038~amino acid activation 21 0.93 0.00 3.21GOTERM_BP_FAT GO:0006575~cellular amino acid derivative metabolic process 48 2.12 0.00 2.03

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GOTERM_BP_FAT GO:0006892~post-Golgi vesicle-mediated transport 24 1.06 0.00 2.91GOTERM_BP_FAT GO:0006511~ubiquitin-dependent protein catabolic process 63 2.78 0.00 1.83GOTERM_BP_FAT GO:0009259~ribonucleotide metabolic process 44 1.94 0.00 2.10GOTERM_BP_FAT GO:0034599~cellular response to oxidative stress 20 0.88 0.00 3.27GOTERM_BP_FAT GO:0051494~negative regulation of cytoskeleton organization 23 1.02 0.00 2.94GOTERM_BP_FAT GO:0046395~carboxylic acid catabolic process 36 1.59 0.00 2.28GOTERM_BP_FAT GO:0016054~organic acid catabolic process 36 1.59 0.00 2.28GOTERM_BP_FAT GO:0050817~coagulation 34 1.50 0.00 2.34GOTERM_BP_FAT GO:0007596~blood coagulation 34 1.50 0.00 2.34GOTERM_BP_FAT GO:0032956~regulation of actin cytoskeleton organization 31 1.37 0.00 2.45GOTERM_BP_FAT GO:0016050~vesicle organization 22 0.97 0.00 2.97GOTERM_BP_FAT GO:0051604~protein maturation 38 1.68 0.00 2.19GOTERM_BP_FAT GO:0043242~negative regulation of protein complex disassembly 19 0.84 0.00 3.26GOTERM_BP_FAT GO:0030834~regulation of actin filament depolymerization 15 0.66 0.00 3.91GOTERM_BP_FAT GO:0031333~negative regulation of protein complex assembly 17 0.75 0.00 3.52GOTERM_BP_FAT GO:0043648~dicarboxylic acid metabolic process 17 0.75 0.00 3.52GOTERM_BP_FAT GO:0009150~purine ribonucleotide metabolic process 41 1.81 0.00 2.09GOTERM_BP_FAT GO:0006901~vesicle coating 11 0.49 0.00 5.16GOTERM_BP_FAT GO:0006957~complement activation, alternative pathway 11 0.49 0.00 5.16GOTERM_BP_FAT GO:0002449~lymphocyte mediated immunity 26 1.15 0.00 2.61GOTERM_BP_FAT GO:0032970~regulation of actin filament-based process 31 1.37 0.00 2.37GOTERM_BP_FAT GO:0019319~hexose biosynthetic process 16 0.71 0.00 3.63GOTERM_BP_FAT GO:0016064~immunoglobulin mediated immune response 22 0.97 0.00 2.86GOTERM_BP_FAT GO:0006081~cellular aldehyde metabolic process 15 0.66 0.00 3.77GOTERM_BP_FAT GO:0016051~carbohydrate biosynthetic process 34 1.50 0.00 2.23GOTERM_BP_FAT GO:0006734~NADH metabolic process 8 0.35 0.00 7.03GOTERM_BP_FAT GO:0044242~cellular lipid catabolic process 27 1.19 0.00 2.50GOTERM_BP_FAT GO:0042743~hydrogen peroxide metabolic process 14 0.62 0.00 3.94GOTERM_BP_FAT GO:0006094~gluconeogenesis 14 0.62 0.00 3.94GOTERM_BP_FAT GO:0009144~purine nucleoside triphosphate metabolic process 37 1.63 0.00 2.13GOTERM_BP_FAT GO:0009062~fatty acid catabolic process 17 0.75 0.00 3.32GOTERM_BP_FAT GO:0006900~membrane budding 11 0.49 0.00 4.83GOTERM_BP_FAT GO:0032272~negative regulation of protein polymerization 15 0.66 0.00 3.64GOTERM_BP_FAT GO:0006953~acute-phase response 18 0.79 0.00 3.16GOTERM_BP_FAT GO:0019724~B cell mediated immunity 22 0.97 0.00 2.76GOTERM_BP_FAT GO:0042274~ribosomal small subunit biogenesis 9 0.40 0.00 5.75GOTERM_BP_FAT GO:0044271~nitrogen compound biosynthetic process 75 3.31 0.00 1.62GOTERM_BP_FAT GO:0006413~translational initiation 19 0.84 0.00 2.97GOTERM_BP_FAT GO:0006959~humoral immune response 27 1.19 0.00 2.40GOTERM_BP_FAT GO:0050878~regulation of body fluid levels 40 1.77 0.00 1.99GOTERM_BP_FAT GO:0031589~cell-substrate adhesion 31 1.37 0.00 2.22GOTERM_BP_FAT GO:0009205~purine ribonucleoside triphosphate metabolic process 35 1.54 0.00 2.10GOTERM_BP_FAT GO:0006000~fructose metabolic process 11 0.49 0.00 4.55GOTERM_BP_FAT GO:0008360~regulation of cell shape 21 0.93 0.00 2.73GOTERM_BP_FAT GO:0007266~Rho protein signal transduction 17 0.75 0.00 3.15GOTERM_BP_FAT GO:0044270~nitrogen compound catabolic process 24 1.06 0.00 2.52GOTERM_BP_FAT GO:0006800~oxygen and reactive oxygen species metabolic process 24 1.06 0.00 2.52GOTERM_BP_FAT GO:0009199~ribonucleoside triphosphate metabolic process 35 1.54 0.00 2.09GOTERM_BP_FAT GO:0007005~mitochondrion organization 39 1.72 0.00 1.99GOTERM_BP_FAT GO:0006098~pentose-phosphate shunt 8 0.35 0.00 6.25GOTERM_BP_FAT GO:0030835~negative regulation of actin filament depolymerization 13 0.57 0.00 3.81GOTERM_BP_FAT GO:0000278~mitotic cell cycle 82 3.62 0.00 1.56GOTERM_BP_FAT GO:0051605~protein maturation by peptide bond cleavage 28 1.24 0.00 2.29GOTERM_BP_FAT GO:0002443~leukocyte mediated immunity 28 1.24 0.00 2.29GOTERM_BP_FAT GO:0010038~response to metal ion 37 1.63 0.00 2.02GOTERM_BP_FAT GO:0002252~immune effector process 38 1.68 0.00 1.99GOTERM_BP_FAT GO:0046034~ATP metabolic process 32 1.41 0.00 2.14GOTERM_BP_FAT GO:0019395~fatty acid oxidation 17 0.75 0.00 3.06GOTERM_BP_FAT GO:0034440~lipid oxidation 17 0.75 0.00 3.06GOTERM_BP_FAT GO:0010639~negative regulation of organelle organization 27 1.19 0.00 2.32GOTERM_BP_FAT GO:0009146~purine nucleoside triphosphate catabolic process 12 0.53 0.00 4.02GOTERM_BP_FAT GO:0046394~carboxylic acid biosynthetic process 42 1.85 0.00 1.91GOTERM_BP_FAT GO:0016053~organic acid biosynthetic process 42 1.85 0.00 1.91GOTERM_BP_FAT GO:0030837~negative regulation of actin filament polymerization 14 0.62 0.00 3.52GOTERM_BP_FAT GO:0048199~vesicle targeting, to, from or within Golgi 9 0.40 0.00 5.27GOTERM_BP_FAT GO:0015669~gas transport 11 0.49 0.00 4.30

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GOTERM_BP_FAT GO:0030705~cytoskeleton-dependent intracellular transport 20 0.88 0.00 2.70GOTERM_BP_FAT GO:0009141~nucleoside triphosphate metabolic process 37 1.63 0.00 1.99GOTERM_BP_FAT GO:0009261~ribonucleotide catabolic process 13 0.57 0.00 3.66GOTERM_BP_FAT GO:0016485~protein processing 33 1.46 0.00 2.07GOTERM_BP_FAT GO:0044087~regulation of cellular component biogenesis 39 1.72 0.00 1.93GOTERM_BP_FAT GO:0006605~protein targeting 53 2.34 0.00 1.73GOTERM_BP_FAT GO:0006944~membrane fusion 20 0.88 0.00 2.65GOTERM_BP_FAT GO:0045087~innate immune response 38 1.68 0.00 1.94GOTERM_BP_FAT GO:0051693~actin filament capping 12 0.53 0.00 3.84GOTERM_BP_FAT GO:0010608~posttranscriptional regulation of gene expression 52 2.29 0.00 1.73GOTERM_BP_FAT GO:0002253~activation of immune response 29 1.28 0.00 2.17GOTERM_BP_FAT GO:0050818~regulation of coagulation 17 0.75 0.00 2.92GOTERM_BP_FAT GO:0030198~extracellular matrix organization 31 1.37 0.00 2.10GOTERM_BP_FAT GO:0009260~ribonucleotide biosynthetic process 35 1.54 0.00 1.98GOTERM_BP_FAT GO:0042060~wound healing 48 2.12 0.00 1.77GOTERM_BP_FAT GO:0009207~purine ribonucleoside triphosphate catabolic process 11 0.49 0.00 4.07GOTERM_BP_FAT GO:0009203~ribonucleoside triphosphate catabolic process 11 0.49 0.00 4.07GOTERM_BP_FAT GO:0006103~2-oxoglutarate metabolic process 8 0.35 0.00 5.62GOTERM_BP_FAT GO:0048205~COPI coating of Golgi vesicle 8 0.35 0.00 5.62GOTERM_BP_FAT GO:0048194~Golgi vesicle budding 8 0.35 0.00 5.62GOTERM_BP_FAT GO:0048200~Golgi transport vesicle coating 8 0.35 0.00 5.62GOTERM_BP_FAT GO:0006200~ATP catabolic process 10 0.44 0.00 4.39GOTERM_BP_FAT GO:0034614~cellular response to reactive oxygen species 14 0.62 0.00 3.28GOTERM_BP_FAT GO:0050820~positive regulation of coagulation 9 0.40 0.00 4.87GOTERM_BP_FAT GO:0007017~microtubule-based process 59 2.60 0.00 1.64GOTERM_BP_FAT GO:0009154~purine ribonucleotide catabolic process 12 0.53 0.00 3.67GOTERM_BP_FAT GO:0051640~organelle localization 28 1.24 0.00 2.14GOTERM_BP_FAT GO:0051656~establishment of organelle localization 23 1.02 0.00 2.34GOTERM_BP_FAT GO:0009152~purine ribonucleotide biosynthetic process 33 1.46 0.00 1.98GOTERM_BP_FAT GO:0006163~purine nucleotide metabolic process 46 2.03 0.00 1.74GOTERM_BP_FAT GO:0030100~regulation of endocytosis 21 0.93 0.00 2.42GOTERM_BP_FAT GO:0007160~cell-matrix adhesion 27 1.19 0.00 2.13GOTERM_BP_FAT GO:0042744~hydrogen peroxide catabolic process 10 0.44 0.00 4.14GOTERM_BP_FAT GO:0009143~nucleoside triphosphate catabolic process 12 0.53 0.00 3.52GOTERM_BP_FAT GO:0009145~purine nucleoside triphosphate biosynthetic process 29 1.28 0.00 2.06GOTERM_BP_FAT GO:0030865~cortical cytoskeleton organization 9 0.40 0.00 4.52GOTERM_BP_FAT GO:0034404~nucleobase, nucleoside and nucleotide biosynthetic process 47 2.07 0.00 1.71GOTERM_BP_FAT GO:0034654~nucleobase, nucleoside, nucleotide and nucleic acid biosyntheti 47 2.07 0.00 1.71GOTERM_BP_FAT GO:0006890~retrograde vesicle-mediated transport, Golgi to ER 11 0.49 0.00 3.68GOTERM_BP_FAT GO:0051017~actin filament bundle formation 11 0.49 0.00 3.68GOTERM_BP_FAT GO:0019835~cytolysis 11 0.49 0.00 3.68GOTERM_BP_FAT GO:0007015~actin filament organization 23 1.02 0.00 2.25GOTERM_BP_FAT GO:0006818~hydrogen transport 21 0.93 0.00 2.34GOTERM_BP_FAT GO:0019674~NAD metabolic process 12 0.53 0.00 3.37GOTERM_BP_FAT GO:0006164~purine nucleotide biosynthetic process 38 1.68 0.00 1.81GOTERM_BP_FAT GO:0070301~cellular response to hydrogen peroxide 10 0.44 0.00 3.91GOTERM_BP_FAT GO:0019216~regulation of lipid metabolic process 31 1.37 0.00 1.95GOTERM_BP_FAT GO:0006638~neutral lipid metabolic process 18 0.79 0.00 2.53GOTERM_BP_FAT GO:0009142~nucleoside triphosphate biosynthetic process 29 1.28 0.00 2.00GOTERM_BP_FAT GO:0009165~nucleotide biosynthetic process 45 1.99 0.00 1.70GOTERM_BP_FAT GO:0051235~maintenance of location 21 0.93 0.00 2.31GOTERM_BP_FAT GO:0007018~microtubule-based movement 31 1.37 0.00 1.93GOTERM_BP_FAT GO:0009206~purine ribonucleoside triphosphate biosynthetic process 28 1.24 0.00 2.01GOTERM_BP_FAT GO:0006903~vesicle targeting 11 0.49 0.00 3.52GOTERM_BP_FAT GO:0051917~regulation of fibrinolysis 7 0.31 0.00 5.47GOTERM_BP_FAT GO:0006754~ATP biosynthetic process 26 1.15 0.00 2.05GOTERM_BP_FAT GO:0042592~homeostatic process 140 6.18 0.00 1.31GOTERM_BP_FAT GO:0009201~ribonucleoside triphosphate biosynthetic process 28 1.24 0.00 1.99GOTERM_BP_FAT GO:0006913~nucleocytoplasmic transport 39 1.72 0.00 1.76GOTERM_BP_FAT GO:0033365~protein localization in organelle 37 1.63 0.00 1.78GOTERM_BP_FAT GO:0000302~response to reactive oxygen species 23 1.02 0.00 2.16GOTERM_BP_FAT GO:0006641~triglyceride metabolic process 16 0.71 0.00 2.62GOTERM_BP_FAT GO:0006954~inflammatory response 69 3.05 0.00 1.49GOTERM_BP_FAT GO:0015992~proton transport 20 0.88 0.00 2.31GOTERM_BP_FAT GO:0009064~glutamine family amino acid metabolic process 18 0.79 0.00 2.43GOTERM_BP_FAT GO:0017038~protein import 34 1.50 0.00 1.82

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GOTERM_BP_FAT GO:0051259~protein oligomerization 42 1.85 0.00 1.70GOTERM_BP_FAT GO:0051169~nuclear transport 39 1.72 0.00 1.74GOTERM_BP_FAT GO:0051651~maintenance of location in cell 17 0.75 0.00 2.49GOTERM_BP_FAT GO:0022406~membrane docking 13 0.57 0.00 2.95GOTERM_BP_FAT GO:0060627~regulation of vesicle-mediated transport 27 1.19 0.00 1.98GOTERM_BP_FAT GO:0034381~lipoprotein particle clearance 9 0.40 0.00 3.96GOTERM_BP_FAT GO:0002460~adaptive immune response based on somatic recombination of im 23 1.02 0.00 2.10GOTERM_BP_FAT GO:0002250~adaptive immune response 23 1.02 0.00 2.10GOTERM_BP_FAT GO:0015986~ATP synthesis coupled proton transport 15 0.66 0.00 2.64GOTERM_BP_FAT GO:0015985~energy coupled proton transport, down electrochemical gradient 15 0.66 0.00 2.64GOTERM_BP_FAT GO:0034655~nucleobase, nucleoside, nucleotide and nucleic acid catabolic p 19 0.84 0.00 2.30GOTERM_BP_FAT GO:0034656~nucleobase, nucleoside and nucleotide catabolic process 19 0.84 0.00 2.30GOTERM_BP_FAT GO:0019725~cellular homeostasis 92 4.06 0.00 1.39GOTERM_BP_FAT GO:0006639~acylglycerol metabolic process 17 0.75 0.00 2.44GOTERM_BP_FAT GO:0032886~regulation of microtubule-based process 17 0.75 0.00 2.44GOTERM_BP_FAT GO:0030193~regulation of blood coagulation 14 0.62 0.00 2.73GOTERM_BP_FAT GO:0034367~macromolecular complex remodeling 10 0.44 0.00 3.52GOTERM_BP_FAT GO:0034369~plasma lipoprotein particle remodeling 10 0.44 0.00 3.52GOTERM_BP_FAT GO:0034368~protein-lipid complex remodeling 10 0.44 0.00 3.52GOTERM_BP_FAT GO:0030866~cortical actin cytoskeleton organization 8 0.35 0.00 4.33GOTERM_BP_FAT GO:0015671~oxygen transport 8 0.35 0.00 4.33GOTERM_BP_FAT GO:0006002~fructose 6-phosphate metabolic process 6 0.26 0.00 6.03GOTERM_BP_FAT GO:0007159~leukocyte adhesion 12 0.53 0.00 3.01GOTERM_BP_FAT GO:0006107~oxaloacetate metabolic process 7 0.31 0.00 4.92GOTERM_BP_FAT GO:0042273~ribosomal large subunit biogenesis 7 0.31 0.00 4.92GOTERM_BP_FAT GO:0030194~positive regulation of blood coagulation 7 0.31 0.00 4.92GOTERM_BP_FAT GO:0018279~protein amino acid N-linked glycosylation via asparagine 7 0.31 0.00 4.92GOTERM_BP_FAT GO:0018196~peptidyl-asparagine modification 7 0.31 0.00 4.92GOTERM_BP_FAT GO:0016042~lipid catabolic process 41 1.81 0.00 1.67GOTERM_BP_FAT GO:0015918~sterol transport 14 0.62 0.00 2.66GOTERM_BP_FAT GO:0030301~cholesterol transport 14 0.62 0.00 2.66GOTERM_BP_FAT GO:0000059~protein import into nucleus, docking 9 0.40 0.00 3.72GOTERM_BP_FAT GO:0051650~establishment of vesicle localization 13 0.57 0.00 2.77GOTERM_BP_FAT GO:0006195~purine nucleotide catabolic process 13 0.57 0.00 2.77GOTERM_BP_FAT GO:0051260~protein homooligomerization 26 1.15 0.00 1.92GOTERM_BP_FAT GO:0009166~nucleotide catabolic process 17 0.75 0.00 2.34GOTERM_BP_FAT GO:0006662~glycerol ether metabolic process 17 0.75 0.00 2.34GOTERM_BP_FAT GO:0008652~cellular amino acid biosynthetic process 17 0.75 0.00 2.34GOTERM_BP_FAT GO:0070507~regulation of microtubule cytoskeleton organization 15 0.66 0.00 2.51GOTERM_BP_FAT GO:0010941~regulation of cell death 147 6.49 0.00 1.27GOTERM_BP_FAT GO:0060548~negative regulation of cell death 73 3.22 0.00 1.43GOTERM_BP_FAT GO:0042542~response to hydrogen peroxide 18 0.79 0.00 2.26GOTERM_BP_FAT GO:0043067~regulation of programmed cell death 146 6.44 0.00 1.26GOTERM_BP_FAT GO:0052547~regulation of peptidase activity 24 1.06 0.00 1.96GOTERM_BP_FAT GO:0006606~protein import into nucleus 24 1.06 0.00 1.96GOTERM_BP_FAT GO:0006102~isocitrate metabolic process 5 0.22 0.00 7.03GOTERM_BP_FAT GO:0030388~fructose 1,6-bisphosphate metabolic process 5 0.22 0.00 7.03GOTERM_BP_FAT GO:0022614~membrane to membrane docking 5 0.22 0.00 7.03GOTERM_BP_FAT GO:0050778~positive regulation of immune response 35 1.54 0.00 1.70GOTERM_BP_FAT GO:0022402~cell cycle process 106 4.68 0.00 1.32GOTERM_BP_FAT GO:0046700~heterocycle catabolic process 22 0.97 0.00 2.01GOTERM_BP_FAT GO:0051289~protein homotetramerization 11 0.49 0.00 2.97GOTERM_BP_FAT GO:0050819~negative regulation of coagulation 11 0.49 0.00 2.97GOTERM_BP_FAT GO:0019321~pentose metabolic process 7 0.31 0.00 4.47GOTERM_BP_FAT GO:0043069~negative regulation of programmed cell death 72 3.18 0.00 1.41GOTERM_BP_FAT GO:0042981~regulation of apoptosis 144 6.35 0.00 1.26GOTERM_BP_FAT GO:0018904~organic ether metabolic process 17 0.75 0.00 2.26GOTERM_BP_FAT GO:0007016~cytoskeletal anchoring at plasma membrane 6 0.26 0.00 5.27GOTERM_BP_FAT GO:0016601~Rac protein signal transduction 6 0.26 0.00 5.27GOTERM_BP_FAT GO:0043066~negative regulation of apoptosis 71 3.13 0.00 1.41GOTERM_BP_FAT GO:0051170~nuclear import 24 1.06 0.00 1.92GOTERM_BP_FAT GO:0034220~ion transmembrane transport 16 0.71 0.00 2.30GOTERM_BP_FAT GO:0022604~regulation of cell morphogenesis 32 1.41 0.00 1.72GOTERM_BP_FAT GO:0006790~sulfur metabolic process 29 1.28 0.00 1.77GOTERM_BP_FAT GO:0006767~water-soluble vitamin metabolic process 14 0.62 0.00 2.46GOTERM_BP_FAT GO:0007568~aging 28 1.24 0.00 1.79

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GOTERM_BP_FAT GO:0030258~lipid modification 20 0.88 0.00 2.04GOTERM_BP_FAT GO:0033344~cholesterol efflux 9 0.40 0.00 3.33GOTERM_BP_FAT GO:0009112~nucleobase metabolic process 10 0.44 0.00 3.06GOTERM_BP_FAT GO:0005976~polysaccharide metabolic process 28 1.24 0.00 1.77GOTERM_BP_FAT GO:0030203~glycosaminoglycan metabolic process 17 0.75 0.00 2.17GOTERM_BP_FAT GO:0006022~aminoglycan metabolic process 19 0.84 0.00 2.06GOTERM_BP_FAT GO:0006446~regulation of translational initiation 14 0.62 0.00 2.40GOTERM_BP_FAT GO:0007006~mitochondrial membrane organization 12 0.53 0.00 2.64GOTERM_BP_FAT GO:0065005~protein-lipid complex assembly 7 0.31 0.00 4.10GOTERM_BP_FAT GO:0006906~vesicle fusion 7 0.31 0.00 4.10GOTERM_BP_FAT GO:0034377~plasma lipoprotein particle assembly 7 0.31 0.00 4.10GOTERM_BP_FAT GO:0031032~actomyosin structure organization 11 0.49 0.00 2.76GOTERM_BP_FAT GO:0051648~vesicle localization 13 0.57 0.00 2.47GOTERM_BP_FAT GO:0050727~regulation of inflammatory response 21 0.93 0.00 1.94GOTERM_BP_FAT GO:0043691~reverse cholesterol transport 8 0.35 0.00 3.52GOTERM_BP_FAT GO:0001959~regulation of cytokine-mediated signaling pathway 8 0.35 0.00 3.52GOTERM_BP_FAT GO:0009113~purine base biosynthetic process 6 0.26 0.00 4.69GOTERM_BP_FAT GO:0070613~regulation of protein processing 5 0.22 0.00 5.86GOTERM_BP_FAT GO:0010896~regulation of triglyceride catabolic process 5 0.22 0.00 5.86GOTERM_BP_FAT GO:0010953~regulation of protein maturation by peptide bond cleavage 5 0.22 0.00 5.86GOTERM_BP_FAT GO:0034384~high-density lipoprotein particle clearance 5 0.22 0.00 5.86GOTERM_BP_FAT GO:0051918~negative regulation of fibrinolysis 5 0.22 0.00 5.86GOTERM_BP_FAT GO:0010970~microtubule-based transport 11 0.49 0.00 2.67GOTERM_BP_FAT GO:0006417~regulation of translation 32 1.41 0.01 1.64GOTERM_BP_FAT GO:0030155~regulation of cell adhesion 32 1.41 0.01 1.64GOTERM_BP_FAT GO:0034504~protein localization in nucleus 24 1.06 0.01 1.80GOTERM_BP_FAT GO:0048284~organelle fusion 9 0.40 0.01 3.01GOTERM_BP_FAT GO:0009719~response to endogenous stimulus 77 3.40 0.01 1.34GOTERM_BP_FAT GO:0006334~nucleosome assembly 22 0.97 0.01 1.84GOTERM_BP_FAT GO:0051004~regulation of lipoprotein lipase activity 8 0.35 0.01 3.31GOTERM_BP_FAT GO:0043281~regulation of caspase activity 21 0.93 0.01 1.87GOTERM_BP_FAT GO:0006839~mitochondrial transport 19 0.84 0.01 1.94GOTERM_BP_FAT GO:0009116~nucleoside metabolic process 18 0.79 0.01 1.98GOTERM_BP_FAT GO:0006919~activation of caspase activity 16 0.71 0.01 2.08GOTERM_BP_FAT GO:0043062~extracellular structure organization 36 1.59 0.01 1.55GOTERM_BP_FAT GO:0006766~vitamin metabolic process 20 0.88 0.01 1.87GOTERM_BP_FAT GO:0033700~phospholipid efflux 6 0.26 0.01 4.22GOTERM_BP_FAT GO:0015931~nucleobase, nucleoside, nucleotide and nucleic acid transport 27 1.19 0.01 1.68GOTERM_BP_FAT GO:0050657~nucleic acid transport 24 1.06 0.01 1.74GOTERM_BP_FAT GO:0051236~establishment of RNA localization 24 1.06 0.01 1.74GOTERM_BP_FAT GO:0050658~RNA transport 24 1.06 0.01 1.74GOTERM_BP_FAT GO:0009309~amine biosynthetic process 21 0.93 0.01 1.82GOTERM_BP_FAT GO:0006879~cellular iron ion homeostasis 11 0.49 0.01 2.49GOTERM_BP_FAT GO:0008088~axon cargo transport 8 0.35 0.01 3.12GOTERM_BP_FAT GO:0046112~nucleobase biosynthetic process 7 0.31 0.01 3.52GOTERM_BP_FAT GO:0031497~chromatin assembly 22 0.97 0.01 1.78GOTERM_BP_FAT GO:0055072~iron ion homeostasis 12 0.53 0.01 2.34GOTERM_BP_FAT GO:0052548~regulation of endopeptidase activity 21 0.93 0.01 1.80GOTERM_BP_FAT GO:0055088~lipid homeostasis 15 0.66 0.01 2.07GOTERM_BP_FAT GO:0033559~unsaturated fatty acid metabolic process 15 0.66 0.01 2.07GOTERM_BP_FAT GO:0043524~negative regulation of neuron apoptosis 15 0.66 0.01 2.07GOTERM_BP_FAT GO:0034728~nucleosome organization 23 1.02 0.01 1.74GOTERM_BP_FAT GO:0051131~chaperone-mediated protein complex assembly 5 0.22 0.01 5.02GOTERM_BP_FAT GO:0006101~citrate metabolic process 5 0.22 0.01 5.02GOTERM_BP_FAT GO:0034446~substrate adhesion-dependent cell spreading 5 0.22 0.01 5.02GOTERM_BP_FAT GO:0010873~positive regulation of cholesterol esterification 5 0.22 0.01 5.02GOTERM_BP_FAT GO:0007008~outer mitochondrial membrane organization 4 0.18 0.01 7.03GOTERM_BP_FAT GO:0060334~regulation of interferon-gamma-mediated signaling pathway 4 0.18 0.01 7.03GOTERM_BP_FAT GO:0007097~nuclear migration 4 0.18 0.01 7.03GOTERM_BP_FAT GO:0070096~mitochondrial outer membrane translocase complex assembly 4 0.18 0.01 7.03GOTERM_BP_FAT GO:0030048~actin filament-based movement 9 0.40 0.01 2.75GOTERM_BP_FAT GO:0042364~water-soluble vitamin biosynthetic process 9 0.40 0.01 2.75GOTERM_BP_FAT GO:0030195~negative regulation of blood coagulation 9 0.40 0.01 2.75GOTERM_BP_FAT GO:0031647~regulation of protein stability 13 0.57 0.01 2.18GOTERM_BP_FAT GO:0006888~ER to Golgi vesicle-mediated transport 13 0.57 0.01 2.18GOTERM_BP_FAT GO:0006690~icosanoid metabolic process 14 0.62 0.01 2.09

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GOTERM_BP_FAT GO:0006403~RNA localization 24 1.06 0.01 1.69GOTERM_BP_FAT GO:0006692~prostanoid metabolic process 8 0.35 0.01 2.96GOTERM_BP_FAT GO:0006693~prostaglandin metabolic process 8 0.35 0.01 2.96GOTERM_BP_FAT GO:0009084~glutamine family amino acid biosynthetic process 8 0.35 0.01 2.96GOTERM_BP_FAT GO:0009110~vitamin biosynthetic process 10 0.44 0.01 2.51GOTERM_BP_FAT GO:0000272~polysaccharide catabolic process 10 0.44 0.01 2.51GOTERM_BP_FAT GO:0050821~protein stabilization 10 0.44 0.01 2.51GOTERM_BP_FAT GO:0043030~regulation of macrophage activation 6 0.26 0.01 3.84GOTERM_BP_FAT GO:0007052~mitotic spindle organization 7 0.31 0.01 3.28GOTERM_BP_FAT GO:0051270~regulation of cell motion 40 1.77 0.01 1.46GOTERM_BP_FAT GO:0032535~regulation of cellular component size 53 2.34 0.01 1.38GOTERM_BP_FAT GO:0042632~cholesterol homeostasis 12 0.53 0.01 2.22GOTERM_BP_FAT GO:0055092~sterol homeostasis 12 0.53 0.01 2.22GOTERM_BP_FAT GO:0007162~negative regulation of cell adhesion 13 0.57 0.01 2.13GOTERM_BP_FAT GO:0009108~coenzyme biosynthetic process 18 0.79 0.01 1.83GOTERM_BP_FAT GO:0032101~regulation of response to external stimulus 34 1.50 0.01 1.50GOTERM_BP_FAT GO:0065004~protein-DNA complex assembly 22 0.97 0.02 1.70GOTERM_BP_FAT GO:0010952~positive regulation of peptidase activity 16 0.71 0.02 1.91GOTERM_BP_FAT GO:0043280~positive regulation of caspase activity 16 0.71 0.02 1.91GOTERM_BP_FAT GO:0046128~purine ribonucleoside metabolic process 10 0.44 0.02 2.42GOTERM_BP_FAT GO:0042278~purine nucleoside metabolic process 10 0.44 0.02 2.42GOTERM_BP_FAT GO:0032374~regulation of cholesterol transport 8 0.35 0.02 2.81GOTERM_BP_FAT GO:0032371~regulation of sterol transport 8 0.35 0.02 2.81GOTERM_BP_FAT GO:0009725~response to hormone stimulus 68 3.00 0.02 1.30GOTERM_BP_FAT GO:0051262~protein tetramerization 12 0.53 0.02 2.16GOTERM_BP_FAT GO:0006266~DNA ligation 5 0.22 0.02 4.39GOTERM_BP_FAT GO:0042451~purine nucleoside biosynthetic process 5 0.22 0.02 4.39GOTERM_BP_FAT GO:0010872~regulation of cholesterol esterification 5 0.22 0.02 4.39GOTERM_BP_FAT GO:0042455~ribonucleoside biosynthetic process 5 0.22 0.02 4.39GOTERM_BP_FAT GO:0046129~purine ribonucleoside biosynthetic process 5 0.22 0.02 4.39GOTERM_BP_FAT GO:0050690~regulation of defense response to virus by virus 5 0.22 0.02 4.39GOTERM_BP_FAT GO:0009163~nucleoside biosynthetic process 5 0.22 0.02 4.39GOTERM_BP_FAT GO:0009081~branched chain family amino acid metabolic process 7 0.31 0.02 3.08GOTERM_BP_FAT GO:0006536~glutamate metabolic process 7 0.31 0.02 3.08GOTERM_BP_FAT GO:0006458~'de novo' protein folding 7 0.31 0.02 3.08GOTERM_BP_FAT GO:0051345~positive regulation of hydrolase activity 37 1.63 0.02 1.45GOTERM_BP_FAT GO:0051028~mRNA transport 21 0.93 0.02 1.70GOTERM_BP_FAT GO:0042692~muscle cell differentiation 27 1.19 0.02 1.57GOTERM_BP_FAT GO:0042730~fibrinolysis 6 0.26 0.02 3.52GOTERM_BP_FAT GO:0046503~glycerolipid catabolic process 6 0.26 0.02 3.52GOTERM_BP_FAT GO:0051592~response to calcium ion 15 0.66 0.02 1.92GOTERM_BP_FAT GO:0032368~regulation of lipid transport 10 0.44 0.02 2.34GOTERM_BP_FAT GO:0007051~spindle organization 13 0.57 0.02 2.03GOTERM_BP_FAT GO:0030334~regulation of cell migration 35 1.54 0.02 1.46GOTERM_BP_FAT GO:0007584~response to nutrient 30 1.32 0.02 1.51GOTERM_BP_FAT GO:0009408~response to heat 15 0.66 0.02 1.88GOTERM_BP_FAT GO:0043101~purine salvage 4 0.18 0.02 5.62GOTERM_BP_FAT GO:0048261~negative regulation of receptor-mediated endocytosis 4 0.18 0.02 5.62GOTERM_BP_FAT GO:0034380~high-density lipoprotein particle assembly 4 0.18 0.02 5.62GOTERM_BP_FAT GO:0010901~regulation of very-low-density lipoprotein particle remodeling 4 0.18 0.02 5.62GOTERM_BP_FAT GO:0006063~uronic acid metabolic process 4 0.18 0.02 5.62GOTERM_BP_FAT GO:0019585~glucuronate metabolic process 4 0.18 0.02 5.62GOTERM_BP_FAT GO:0009188~ribonucleoside diphosphate biosynthetic process 4 0.18 0.02 5.62GOTERM_BP_FAT GO:0009136~purine nucleoside diphosphate biosynthetic process 4 0.18 0.02 5.62GOTERM_BP_FAT GO:0009180~purine ribonucleoside diphosphate biosynthetic process 4 0.18 0.02 5.62GOTERM_BP_FAT GO:0010898~positive regulation of triglyceride catabolic process 4 0.18 0.02 5.62GOTERM_BP_FAT GO:0006014~D-ribose metabolic process 4 0.18 0.02 5.62GOTERM_BP_FAT GO:0006172~ADP biosynthetic process 4 0.18 0.02 5.62GOTERM_BP_FAT GO:0060249~anatomical structure homeostasis 24 1.06 0.02 1.59GOTERM_BP_FAT GO:0009310~amine catabolic process 19 0.84 0.02 1.71GOTERM_BP_FAT GO:0006952~defense response 106 4.68 0.02 1.21GOTERM_BP_FAT GO:0006695~cholesterol biosynthetic process 9 0.40 0.02 2.43GOTERM_BP_FAT GO:0045834~positive regulation of lipid metabolic process 13 0.57 0.02 1.99GOTERM_BP_FAT GO:0000226~microtubule cytoskeleton organization 31 1.37 0.02 1.48GOTERM_BP_FAT GO:0006928~cell motion 84 3.71 0.02 1.24GOTERM_BP_FAT GO:0000375~RNA splicing, via transesterification reactions 32 1.41 0.02 1.47

Page 48: [XLS]media.nature.com · Web viewSupp-Table S2B Supp-Table S2A Gene name UniProt accession Fasta protein description Unique peptides Spectral counts A1BG P04217 >sp|P04217|A1BG_HUMAN

GOTERM_BP_FAT GO:0000377~RNA splicing, via transesterification reactions with bulged adeno 32 1.41 0.02 1.47GOTERM_BP_FAT GO:0000398~nuclear mRNA splicing, via spliceosome 32 1.41 0.02 1.47GOTERM_BP_FAT GO:0034329~cell junction assembly 12 0.53 0.02 2.06GOTERM_BP_FAT GO:0031110~regulation of microtubule polymerization or depolymerization 10 0.44 0.02 2.27GOTERM_BP_FAT GO:0031111~negative regulation of microtubule polymerization or depolymeriz 7 0.31 0.02 2.90GOTERM_BP_FAT GO:0010927~cellular component assembly involved in morphogenesis 11 0.49 0.02 2.15GOTERM_BP_FAT GO:0009063~cellular amino acid catabolic process 17 0.75 0.03 1.76GOTERM_BP_FAT GO:0009894~regulation of catabolic process 22 0.97 0.03 1.61GOTERM_BP_FAT GO:0051291~protein heterooligomerization 14 0.62 0.03 1.89GOTERM_BP_FAT GO:0006997~nucleus organization 14 0.62 0.03 1.89GOTERM_BP_FAT GO:0045103~intermediate filament-based process 8 0.35 0.03 2.56GOTERM_BP_FAT GO:0046461~neutral lipid catabolic process 5 0.22 0.03 3.91GOTERM_BP_FAT GO:0050732~negative regulation of peptidyl-tyrosine phosphorylation 5 0.22 0.03 3.91GOTERM_BP_FAT GO:0046464~acylglycerol catabolic process 5 0.22 0.03 3.91GOTERM_BP_FAT GO:0031529~ruffle organization 5 0.22 0.03 3.91GOTERM_BP_FAT GO:0034370~triglyceride-rich lipoprotein particle remodeling 5 0.22 0.03 3.91GOTERM_BP_FAT GO:0044269~glycerol ether catabolic process 5 0.22 0.03 3.91GOTERM_BP_FAT GO:0030212~hyaluronan metabolic process 5 0.22 0.03 3.91GOTERM_BP_FAT GO:0031667~response to nutrient levels 39 1.72 0.03 1.39GOTERM_BP_FAT GO:0030168~platelet activation 10 0.44 0.03 2.20GOTERM_BP_FAT GO:0040012~regulation of locomotion 38 1.68 0.03 1.39GOTERM_BP_FAT GO:0022610~biological adhesion 118 5.21 0.03 1.18GOTERM_BP_FAT GO:0045185~maintenance of protein location 13 0.57 0.03 1.90GOTERM_BP_FAT GO:0051346~negative regulation of hydrolase activity 13 0.57 0.03 1.90GOTERM_BP_FAT GO:0006869~lipid transport 30 1.32 0.03 1.45GOTERM_BP_FAT GO:0018130~heterocycle biosynthetic process 15 0.66 0.03 1.79GOTERM_BP_FAT GO:0034660~ncRNA metabolic process 44 1.94 0.03 1.35GOTERM_BP_FAT GO:0006916~anti-apoptosis 40 1.77 0.04 1.37GOTERM_BP_FAT GO:0007049~cell cycle 129 5.69 0.04 1.17GOTERM_BP_FAT GO:0007569~cell aging 10 0.44 0.04 2.13GOTERM_BP_FAT GO:0046716~muscle maintenance 6 0.26 0.04 3.01GOTERM_BP_FAT GO:0006027~glycosaminoglycan catabolic process 6 0.26 0.04 3.01GOTERM_BP_FAT GO:0006144~purine base metabolic process 6 0.26 0.04 3.01GOTERM_BP_FAT GO:0019217~regulation of fatty acid metabolic process 13 0.57 0.04 1.87GOTERM_BP_FAT GO:0051146~striated muscle cell differentiation 20 0.88 0.04 1.60GOTERM_BP_FAT GO:0006323~DNA packaging 25 1.10 0.04 1.50GOTERM_BP_FAT GO:0007155~cell adhesion 117 5.16 0.04 1.18GOTERM_BP_FAT GO:0050748~negative regulation of lipoprotein metabolic process 4 0.18 0.04 4.69GOTERM_BP_FAT GO:0006085~acetyl-CoA biosynthetic process 4 0.18 0.04 4.69GOTERM_BP_FAT GO:0046031~ADP metabolic process 4 0.18 0.04 4.69GOTERM_BP_FAT GO:0006122~mitochondrial electron transport, ubiquinol to cytochrome c 4 0.18 0.04 4.69GOTERM_BP_FAT GO:0043277~apoptotic cell clearance 4 0.18 0.04 4.69GOTERM_BP_FAT GO:0042159~lipoprotein catabolic process 4 0.18 0.04 4.69GOTERM_BP_FAT GO:0019882~antigen processing and presentation 19 0.84 0.04 1.61GOTERM_BP_FAT GO:0009266~response to temperature stimulus 19 0.84 0.04 1.61GOTERM_BP_FAT GO:0006750~glutathione biosynthetic process 5 0.22 0.04 3.52GOTERM_BP_FAT GO:0009185~ribonucleoside diphosphate metabolic process 5 0.22 0.04 3.52GOTERM_BP_FAT GO:0042255~ribosome assembly 5 0.22 0.04 3.52GOTERM_BP_FAT GO:0051647~nucleus localization 5 0.22 0.04 3.52GOTERM_BP_FAT GO:0006399~tRNA metabolic process 25 1.10 0.04 1.49GOTERM_BP_FAT GO:0050688~regulation of defense response to virus 7 0.31 0.04 2.59GOTERM_BP_FAT GO:0030199~collagen fibril organization 9 0.40 0.04 2.18GOTERM_BP_FAT GO:0045807~positive regulation of endocytosis 9 0.40 0.04 2.18GOTERM_BP_FAT GO:0002697~regulation of immune effector process 22 0.97 0.04 1.53GOTERM_BP_FAT GO:0051099~positive regulation of binding 18 0.79 0.04 1.62GOTERM_BP_FAT GO:0051495~positive regulation of cytoskeleton organization 12 0.53 0.05 1.87GOTERM_BP_FAT GO:0048545~response to steroid hormone stimulus 37 1.63 0.05 1.35