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Page 1: Www.strandls.com. Frederick Sanger Nobel Prizes in 1958 & 1980 Watson & Crick Nobel Prize in 1962 Bill Clinton & Francis Collins 195019601970198020002010

www.strandls.com

Page 2: Www.strandls.com. Frederick Sanger Nobel Prizes in 1958 & 1980 Watson & Crick Nobel Prize in 1962 Bill Clinton & Francis Collins 195019601970198020002010

Frederick SangerNobel Prizes in 1958 & 1980

Watson & CrickNobel Prize in 1962

Bill Clinton &

Francis Collins

1950 1960 1970 1980 2000 2010

Discovery ofDNA structure

Development ofSanger Sequencing

Human Genome Project

1990

Next Gen Sequencing

“Genetics became Genomics and

Biology became an Information Science”

Lander / BroadMapping

Page 3: Www.strandls.com. Frederick Sanger Nobel Prizes in 1958 & 1980 Watson & Crick Nobel Prize in 1962 Bill Clinton & Francis Collins 195019601970198020002010

Next Generation Sequencing Costs

Page 4: Www.strandls.com. Frederick Sanger Nobel Prizes in 1958 & 1980 Watson & Crick Nobel Prize in 1962 Bill Clinton & Francis Collins 195019601970198020002010

4

Strand Life Sciences: Genesis00:02:04

The first academic spin-off in India, from the Indian Institute of Science, Bangalore, in

2000

Page 5: Www.strandls.com. Frederick Sanger Nobel Prizes in 1958 & 1980 Watson & Crick Nobel Prize in 1962 Bill Clinton & Francis Collins 195019601970198020002010

InformaticsMeasurement

Analysis / Interpretation

Clinic

Translational

Bioinform

atics

Research

Bioinform

atics

Science

Prim

ary B

ioinformatics

Prim

ary B

ioinformatics

Page 6: Www.strandls.com. Frederick Sanger Nobel Prizes in 1958 & 1980 Watson & Crick Nobel Prize in 1962 Bill Clinton & Francis Collins 195019601970198020002010

www.strandls.com

STRAND LIFE SCIENCES

CORPORATE OVERVIEW

Page 7: Www.strandls.com. Frederick Sanger Nobel Prizes in 1958 & 1980 Watson & Crick Nobel Prize in 1962 Bill Clinton & Francis Collins 195019601970198020002010

www.strandls.com

Agenda

I. Who is Strand?

II. Our Capabilities

III. Our Executive Team

IV. Our Partners

V. Our Strengths

Page 8: Www.strandls.com. Frederick Sanger Nobel Prizes in 1958 & 1980 Watson & Crick Nobel Prize in 1962 Bill Clinton & Francis Collins 195019601970198020002010

www.strandls.comwww.strandls.com

Who is Strand?

Founded in 2000, headquartered in Bangalore, India with US corporate headquarters in San Francisco

India’s first major academic spin-off has 230 employees; 50% computer science and 50% life science & clinical PhDs

Mature personalized medicine business in India

Leaders in genomic research software with 2,000 licenses worldwide and deep relationships with large corporations such as Agilent and L’Oreal

Page 9: Www.strandls.com. Frederick Sanger Nobel Prizes in 1958 & 1980 Watson & Crick Nobel Prize in 1962 Bill Clinton & Francis Collins 195019601970198020002010

www.strandls.comwww.strandls.com

Our Capabilities

• Personalized Medicine

• LDT Testing for Oncology & Inherited Diseases

• StrandOmics™

• A platform for variant interpretation and reporting built for interpreters by interpreters

• GeneSpring®

• Strand® NGS

• Gene expression analysis software covering microarray and newer NGS technologies

Page 10: Www.strandls.com. Frederick Sanger Nobel Prizes in 1958 & 1980 Watson & Crick Nobel Prize in 1962 Bill Clinton & Francis Collins 195019601970198020002010

www.strandls.com

Genomic Software

We build products that are used by thousands of researchers around the world to gain insights into the Omics world: the world of genes, proteins, metabolites, epigenomes and metagenomes.

These insights help us understand what roles these molecules play in health and in disease. And how these roles can be manipulated to design cures.

These insights have contributed to a large body of knowledge captured in several thousand scientific publications.

Currently, Strand software products are offered in the U.S. for research only

Capability Description

GeneSpring® Software for Gene Expression analysis offering an interactive computing environment

Strand® NGS NGS software solution for full-fledged data analysis for all major sequencing applications

StrandOmics™ A platform for variant interpretation and reporting built for interpreters by interpreters

Heptox™ Unique HepatoToxicity Predictive Platform

Page 11: Www.strandls.com. Frederick Sanger Nobel Prizes in 1958 & 1980 Watson & Crick Nobel Prize in 1962 Bill Clinton & Francis Collins 195019601970198020002010

www.strandls.com

Personalized Medicine

We enable clinicians to derive insights from their patient's genomes. We extract this vast genomic information and distill it down to its very essence using knowledge generated from cutting-edge research.

Our powerful capabilities enable clinicians to pinpoint the root cause of disease and identify the right treatment, including treatments in clinical trials.

They also enable clinicians to identify patients at increased risk for many diseases including cancer, and help the clinician and patient work together to prevent disease.

*These panels are research only in the U.S.

Capability* Description

Cancer Panel Strand® Germline Test and Strand® Somatic 48 Gene Test are offered as a standard of cancer care and to support risk screening

Speciality Panels Strand® Eye Genomic Test and Strand® Cardio Genomic Test

Genetic Panels &Known Mutations

Strand® Rare Disease Test and Strand® Single Mutation ConfirmationTest are offered in pre-natal screening, neo-natal check-ups and single mutation confirmations

Page 12: Www.strandls.com. Frederick Sanger Nobel Prizes in 1958 & 1980 Watson & Crick Nobel Prize in 1962 Bill Clinton & Francis Collins 195019601970198020002010

www.strandls.com

Experienced Management Team &Thought Leadership

VIJAY CHANDRU, PhD SCOTT STORRER RAMESH HARIHARAN, PhDKALYANASUNDARAM 'KAS'SUBRAMANIAN, PhD

THIRU P. REDDY

Co-founder, Chairman andChief Executive Officer

• MIT (PhD), Purdue, IISc• Technology Pioneer – WEF• Fellow Indian Academy of

Sciences & Engineering

President, Strand Genomics

• Boston University• General Electric, CIGNA,

Cardinal Health, Genomind

Co-founder and ChiefTechnology Officer

• Courant(PhD), Max Plank, IISc , IIT –D

• MIT TR100

Chief Scientific Officer

• Johns Hopkins (PhD), IIT-B• Novartis, Entelos

Executive Vice President,Business Operations

• West Virginia• Bayer, Incyte

Talent from Premier Institutions & Universities

Board of Directors Advisory Board

VIJAY CHANDRU, PhDCo-founder, Chairman & CEODAVID WETHERELLManaging Partner, Biomark CapitalRAVI VENKATESANEx-Chairman, Microsoft India

RAMESH HARIHARAN, PhDCo-founder and CTODOUGLAS LIND, MDManaging Director, Biomark Capital

CHARLES CANTOR, PhDCHARLES DeLISI, PhDSWAMI MANOHAR, PhDCo-founderV. VINAY, PhDCo- founder

ERIC EASTMAN, PhDKAL RAMNARAYAN, PhDD. BALA SUBRAMANIAN, PhD

Page 13: Www.strandls.com. Frederick Sanger Nobel Prizes in 1958 & 1980 Watson & Crick Nobel Prize in 1962 Bill Clinton & Francis Collins 195019601970198020002010

www.strandls.com

Partners & Customers

Europe

North America

China & Japan

India

Australia

Page 14: Www.strandls.com. Frederick Sanger Nobel Prizes in 1958 & 1980 Watson & Crick Nobel Prize in 1962 Bill Clinton & Francis Collins 195019601970198020002010

www.strandls.com

Strand Strengths

Leaders in genomic software with 1,400 licenses worldwide and growing rapidly

14-year-old company, financially strong and continually investingin innovation

Access to several hundred computer science, life science and clinical science PhDs

Unmatched capabilities in genomic software and personalizedmedicine

Page 15: Www.strandls.com. Frederick Sanger Nobel Prizes in 1958 & 1980 Watson & Crick Nobel Prize in 1962 Bill Clinton & Francis Collins 195019601970198020002010

Thank you