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AIIMS: PHYSIOLOGY (2001 TO 2014)
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day 20 of the menstrual cycle of a young woman. Whether her cycle was ovulatory or not may be validlyassessed by the reported serum levels ofa) FSHb) LHc) Estradiold) Progesterone
Answer: Progesterone
3. The neurons may get irreversibly damaged if exposed to significant hypoxia fora) 8 minb) 2 minc) 30 secd) 15 sec
Answer: 8 min.
AIIMS MAY 20031. Most accurate measurement of extracellular fluid volume (ECF) can be done by usinga) Sucroseb) Mannitolc) Inulind) Aminopyrine
Answer: Inulin
2. There is a mid-cycle shift in the basal body temperature (BBT) after ovulation in women. This is caused by:a) FSH-peakb) LH-peakc) Estradiold) Progesterone
Answer: Progesterone
3. Various cells respond differentially to a second messenger (such as increased cAMP) because they havedifferent.a) Receptorsb) Enzymatic compositionc) Nuclei
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d) Membrane lipids
Answer: Enzymatic composition
4. A shift of posture from supine to upright posture is associated with cardio-vascular adjustments. Which ofthe following is NOT true in this context?a) Rise in central venous pressureb) Rise in heart ratec) Decrease in cardiac outputd) Decrease in stroke volume
Answer: Rise in central venous pressure
5. Osteoclast has specific receptor for:a) Parathyroid hormoneb) Calcitoninc) Thyroxind) Vit D3
Answer: Calcitonin
6. All are correct about potassium balance except.a) Most of potassium is intracellularb) Three quarter of the total body potassium is found in skeletal muscle.c) Intracellular potassium is released into extra- cellular space in response to severe injury or surgicalstress.d) Acidosis leads to movement of potassium from extracellular to intracellular fluid compartment.
Answer: Acidosis leads to movement of potassium from extracellular to intracellular fluid compartment.
7. Hypocalcaemia characterized by all excepta) Numbness and tingling of circum-oral regionb) Hyperactive tendon reflexes and positive Chvostek’s signc) Shortening of Q-T interval in ECGd) Carpo-pedal spasm
Answer: Shortening of Q-T interval in ECG
8. Dystrophic gene mutation leads to:a) Myasthenia gravis
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b) Motor neuron diseasec) Poliomyelitisd) Duchenne Muscular Dystrophy
Answer: Duchenne Muscular Dystrophy
9. The hormone associated with cold adaption is:a) Growth hormoneb) Thyroxinc) Insulind) Melanocyte Stimulating Hormone
Answer: Thyroxin
10. Father to son inheritance is never seen in case of:a) Autosomal dominant inheritanceb) Autosomal recessive inheritancec) X- linked recessive inheritanced) Multi-factorial inheritance
Answer: X- linked recessive inheritance
11. Brain lipid binding protein is expressed by which of the following:a) Mature astrocytesb) Oligodendrocytesc) Purkinje cellsd) Pyramidal neurons
Answer: Mature astrocytes
12. In angina pectoris, the pain radiating down the left arm is mediated by increased activity in afferent(sensory) fibres contained in the:a) Carotid branch of the glosso-pharyngeal nerveb) Phrenic nervec) Vagus nerve and recurrent laryngeal nerved) Thoracic splanchnic nerve
Answer: Thoracic splanchnic nerve
13. A 55-year-old male accident victim in casualty urgently needs blood. The blood bank is unable to
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determine his ABO group, as his red cell group and plasma group do not match. Emergency transfusion ofpatient should be with:a) RBC corresponding to his red cell group and colloids/crystalloid.b) Whole blood corresponding to his plasma group.c) O positive RBC and colloids/ crystalloid.d) AB negative whole blood.
Answer: O positive RBC and colloids/ crystalloid
14. Although more than 400 blood groups have been identified, the ABO blood group system remains themost important in clinical medicine because:a) It was the blood group system to be discoveredb) It has four different blood groups A, B, AB, O (H)c) ABO (H) antigens are present in most body tissues and fluidsd) ABO (H) antibodies are invariably present in plasma when person’s RBC lacks the corresponding antigen
Answer: ABO (H) antibodies are invariably present in plasma when person’s RBC lacks the correspondingantigen
15. The mechanism that protects normal pancreas from auto-digestion isa. Secretion of bicarbonateb. Protease inhibitors present in plasmac. Proteolytic enzyme secreted in inactive formd. The resistance of pancreatic cells
Answer: Proteolytic enzyme secreted in inactive form
AIIMS NOV 20031. In the following food items, which one has the highest Glycemic index?a) Corn flakesb) Brown ricec) Ice-creamd) Whole wheat bread
Answer: Corn flakes
2. Several hormones regulate the tubular re-absorption of water and electrolytes at different sites in thenephron. Which of the following combination is correct?a) Angiotensin in distal tubule
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b) Aldosterone in collecting ductsc) ADH in proximal tubuled) ANP in loop of Henle
Answer: Aldosterone in collecting ducts
3. “Inflation of lungs induces further inflation” is explained by:a) Hering-Breuer inflation reflexb) Hering-Breuer deflation reflexc) Head’s paradoxical reflexd) J-reflex
Answer: Head’s paradoxical reflex
4. If you calculate the plasma osmolality of a child with plasma Na+ 125 mEq/l, glucose 108 mg/dl, and BUN(blood urea nitrogen) 140 mg/dl, the most appropriate answer would be:a) 300 mOsm/ kgb) 306 mOsm/ kgc) 312 mOsm/ kgd) 318 mOsm/ kg
Answer: 306 mOsm/ kg
5. Relative color and luminosity of photoreceptive input under changing light conditions are regulated andmaintained bya) Muller cellsb) Amacrine cellsc) Ganglion cellsd) Retinal astrocytes
Answer: Amacrine cells
6. Exposure to darkness leads to increased melatonin secretion. It is brought about by:a) Decreasing the activity of suprachiasmatic nucleib) Increasing the serotonin N-acetyl transferasec) Decreasing the hydroxy-indole-o-methyl transferase activityd) Blocking the release of nor-epinephrine from sympathetic nerve terminals
Answer: Increasing the serotonin N-acetyl transferase
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AIIMS MAY 20041. The inhibitory neurotransmitter in CNS neurons isa) Glutamateb) Aspartatec) Gamma-amino butyric acidd) Taurine
Answer: Gamma-amino butyric acid
2. Which one of the following clearly states the role of cerebellum in motor performance?a. Planning and programming of movementb. Convert abstract thought into voluntary actionc. Initiation of skilled voluntary actiond. Smoothens and coordinates ongoing movements
Answer: Smoothens and coordinates ongoing movements
3. Which of the following phrase adequately describes Pacinian corpuscles?a. A type of pain receptorsb. Slowly adapting touch receptorsc. Rapidly adapting touch receptorsd. Located in the joints
Answer: Rapidly adapting touch receptors
4. Ovulation is associated with sudden rise in:a. Prolactinb. Testosteronec. LHd. Oxytocin
Answer: LH
5. The normal adult human electroencephalogram (EEG):a. Will show high frequency waves during stage 3 sleepb. Shows alpha rhythm when a person is awake but inattentivec. Has lower frequency waves during mental activityd. Is predominated by large amplitude waves during REM sleep
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Answer: Shows alpha rhythm when a person is awake but inattentive
6. The afferent fibers which are most sensitive to local anesthetic belong to group:a. Ab. Bc. Cd. D
Answer: C
7. Lower esophageal sphincter:a. Has no tonic activityb. Has a tone which is provided by the sympathetic systemc. Relaxes on increasing abdominal pressured. Relaxes ahead of the peristaltic wave
Answer: Relaxes ahead of the peristaltic wave
8. Drinking can be induced by:a. Electrical stimulation of the posterior hypothalamusb. Osmotic stimulation of supra-optic nucleusc. Lesions in the para-ventricular nucleusd. Neuronal lesion of the pre-optic nucleus
Answer: ?
9. When information memorized afterwards is interfered by the information learnt earlier, it is called:a. Retroactive inhibitionb. Proactive inhibitionc. Simple inhibitiond. Inhibition
Answer: Proactive inhibition
10. Wedged hepatic venous pressure represents pressure in:a. Main portal veinb. Main hepatic veinc. Sinusoidsd. Central vein radicles
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Answer: Sinusoids
11. The pressure-volume curve is shifted to the left in:a. Mitral regurgitationb. Aortic regurgitationc. Mitral stenosisd. Aortic stenosis
Answer: Aortic stenosis
12. The intrafusal fibers of the striated skeletal muscles are innervated by one of the following type of motorneurons. Choose the correct answer:a. Alphab. Betac. Gammad. Delta
Answer: GammaExplanation:
13. The correct sequence of cell cycle is:a. G0-G1-S-G2-Mb. G0-G1-G2-S-Mc. G0-M-G2-S-G1d. G0-G1-S-M-G2
Answer: G0-G1-S-G2-M
AIIMS NOV 20041. Erythropoiesis is promoted by all of the following except:a) ACTHb) Thyroxinc) Estrogend) Prolactin
Answer: Estrogen
2. Which of the following is the best-known metabolic function of the lung?a. Inactivation of serotonin
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b. Conversion of angiotensin-I to angiotensin-IIc. Inactivation of Bradykinind. Metabolism of basic drugs by cytochrome P-450 system
Answer: Conversion of angiotensin-I to angiotensin-II
3. When the aviator is subjected to negative G:a. The hydrostatic pressure in veins of lower limb increasesb. The cardiac output decreasesc. Black out occursd. The cerebral arterial pressure rises
Answer: The cerebral arterial pressure rises
4. Which combination of the following statements is correct with reference to hypoxia?A. When it is severe; causes stimulation of the sympathetic nervous systemB. It leads to the accumulation of hydrogen and lactate ionsC. It causes decrease in cerebral blood flowD. If it is chronic, causes rightward shift of oxygen Hb curvea. All of the above statements are correctb. B and Cc. A, B and Dd. B, C and D
Answer: A, B and D
6. Which one of the following acts to increase the release of Ca2+ from endoplasmic reticulum?a. Inositol tri-phosphateb. Parathyroid hormonec. 1, 25-dihydroxy Cholecalciferold. Di-acyglycerol
Answer: Inositol tri-phosphate
7. If a single spinal nerve is cut, the area of tactile loss is always greater than the area of loss of painfulsensations, because:a. Tactile information is carried by myelinated fast conducting firesb. Tactile receptors adapt quicklyc. Degree of overlap of fibres carrying tactile sensation is much less
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d. In the primary sensory cortex tactile sensation is represented on a larger area
Answer: Degree of overlap of fibres carrying tactile sensation is much less
AIIMS MAY 20051. Phantom limb sensations are best described by:a. Weber Fechner Lawb. Fechner’s law of degenerationc. Pascal’s lawd. Law of projection
Answer: Law of projection
2. In a fetus the insulin secretion begins by:a) 3rd monthb) 5th monthc) 7th monthd) 9th month
Answer: 3rd month
3. Which of the following hormones is an example of a peptide hormone?a) Parathormoneb) Adrenalinec) Cortisold) Thyroxin
Answer: Parathormone
AIIMS NOV 20051. All of the following transport processes follow ‘saturation kinetics’ except:a) Facilitated diffusionb) Na+-Ca2+ exchangerc) Simple diffusiond) Na+ coupled active transport
Answer: Simple diffusion
2. An antero-lateral cordotomy relieving pain in right leg is effective because it interrupts the:a. Left dorsal column
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b. Left ventral spino-thalamic tractc. Left lateral spino-thalamic tractd. Right lateral spino-thalamic tract
Answer: Left lateral spino-thalamic tract
4. Pulmonary function abnormalities in interstitial lung diseases include all of the following except:a. Reduced vital capacityb. Reduced FEV1/FVC ratioc. Reduced diffusion capacityd. Reduced total lung capacity
Answer: Reduced FEV1/FVC ratio
5. Which of the following situations will lead to increased viscosity of blood?a. Fasting stateb. Hypoglycemiac. Multiple myelomad. Amyloidogenesis
Answer: Multiple myeloma
6. Fetal hemoglobin has all the following characteristic features except:a. Strong affinity for 2, 3-DPGb. Oxygen dissociation curve is shifted to leftc. At low fetal PO2 gives up more oxygen to tissues than adult hemoglobind. Forms 80% of hemoglobin at birth
Answer: Strong affinity for 2, 3-DPG
7. According to Myogenic hypothesis of renal auto-regulation, the afferent arterioles contract in response tostretch induced by:a. NO releaseb. Nor-adrenaline releasec. Opening of Ca2+ channelsd. Adenosine release
Answer: Opening of Ca2+ channels
8. Beta waveforms in electroencephalogram designate which of the following states of the patient:
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a. Deep Anesthesiab. Surgical Anesthesiac. Light Anesthesia, eyes closed, relaxedd. Awake/alert state
Answer: Awake/alert state
AIIMS MAY 20061. Which of the following organs secrete zinc in large amounts in man?a) Seminal vesicleb) Prostatec) Epididymisd) Vas
Answer: Prostate
2. Cushing’s triad include all except?a) Hypertensionb) Bradycardiac) Hypothermiad) Irregular respiration
Answer: Hypothermia
3. Vanilloid receptors are activated by?a) Painb) Vibrationc) Touchd) Pressure
Answer: Pain
4. The sodium-potassium pump is an example of?a) Active transportb) Passive transportc) Facilitated diffusiond) Osmosis
Answer: Active transport
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5. Which one of the following acts as a second messenger?a) Mg++b) Cl-c) Ca++d) PO4+3
Answer: Ca++
6. Follicular stimulating hormone receptors are present on?a) Theca cellsb) Granulosa cellsc) Leydig cellsd) Basement membrane of ovarian follicle
Answer: Granulosa cells
7. All of the following factors influence hemoglobin dissociation curve excepta) Chloride ion concentrationb) CO2 tensionc) Temperatured) 2, 3 BPG levels
Answer: Chloride ion concentration
8. The main difference between REM sleep and wakefulness is?a) EEG de-synchronizationb) Rapid eye movementsc) Decreased muscle toned) Penile erection
Answer: Decreased muscle tone
9. On electromyography, all of the following features suggest denervation except?a) Unregulated firing of individual muscle fibersb) Small short duration poly-phasic action potentialsc) Presence of positive sharp wavesd) Spontaneous firing of motor units
Answer: Small short duration poly-phasic action potentials
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10. Which one of the following is correct statement regarding coronary blood flow?a) Coronary blood flow is directly related to perfusion pressure and inversely related to resistanceb) Coronary blood flow is inversely related to perfusion pressure and directly related to resistancec) Coronary blood flow is directly related to perfusion pressure and also to resistanced) Coronary blood flow is inversely related to perfusion pressure and also resistance
Answer: Coronary blood flow is directly related to perfusion pressure and inversely related to resistance
AIIMS NOV 20061. Regarding Golgi tendon organ true isa) Dynamic lengthb) Static lengthc) Muscle tensiond) Stimulates the motor neurons of the same
Answer: Muscle tension
2. Increase in threshold level on applying sub-threshold, slowly rising stimulus is k/a(AIIMS May 08)a) Adaptationb) Accommodationc) Refractorinessd) Electro-tonus
Answer: Accommodation
3. Nor-adrenaline, adrenaline and dopamine receptor belong to which family?a) 7 pass receptorb) 2 pass receptorc) 5 pass receptord) Ligand gated
Answer: 7 pass receptor
4. Pulmonary circulation differ from systemic circulationa) Decreased blood volume during systoleb) Pulmonary vasoconstriction in response to hypoxiac) Pulmonary vaso-dilation in response to hypoxiad) Increased basal vasoconstrictor tone
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Answer: Pulmonary vasoconstriction in response to hypoxia
5. Turbulence occurs witha) Low density of bloodb) Reynolds’s number < 1000c) Increase in radius of vesseld) Decrease in flow rate
Answer: Increase in radius of vessel
6. Mean arterial pressure (MAP)a) (SBP + 2 DBP)/3b) (DBP + 2 SBP)/3c) (SBP + 3 DBP)/2d) (DBP + 3 SBP)/2
Answer: (SBP + 2 DBP)/3
7. Which of the following favors filtration at the arteriolar end of the capillary bed?a) Decrease in hydrostatic pressure of capillariesb) Increase in hydrostatic pressure of capillariesc) Increase in oncotic pressure of capillariesd) Decrease in oncotic pressure of interstitium
Answer: Increase in hydrostatic pressure of capillaries
AIIMS MAY 20071. Iron is actively absorbed in:a) Stomachb) Duodenum and proximal jejunumc) Large intestined) Ileum
Answer: Duodenum and proximal jejunum
2. Bile acids are synthesized froma) Cholesterolb) Amino acidsc) Bilirubin
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d) Protein
Answer: Cholesterol
3. Aldosterone receptors are present in all excepta) Liverb) Colonc) Hippocampusd) Distal nephron
Answer: Liver
4. True about free water clearance isa) Regulated by ADHb) Regulated by Aldosteronec) Increased by Frusemided) None of the above
Answer: Regulated by ADH
5. Oxygen delivery to tissues depends on all excepta) Cardiac outputb) Type of fluid administeredc) Hemoglobin concentrationd) Affinity of hemoglobin for Oxygen
Answer: Type of fluid administered
6. In isometric exercise all are increased except:a) Heart rateb) Cardiac outputc) Mean arterial pressured) Systemic vascular resistance
Answer: Systemic vascular resistance
7. Juxta-glomerular apparatus lies in relation toa) Proximal convoluted tubuleb) Ascending loop of Henlec) Descending loop of Henle
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d) Glomerulus
Answer: Glomerulus
8. Renin is secreted bya) PCTb) DCTc) Collecting ductd) Juxta-glomerular apparatus
Answer: Juxta-glomerular apparatus
9. Liver synthesizes all, excepta) C3 complement componentb) Haptoglobinc) Fibrinogend) Immunoglobulin
Answer: Immunoglobulin
10. Cerebral blood flow is regulated by all excepta) Blood pressureb) Arterial PCO2c) Potassium ionsd) Cerebral metabolic rate
Answer: Potassium ions
11. True regarding endothelin-1 are all excepta) Broncho-dilatationb) Vasoconstrictionc) Decreased GFRd) Has inotropic effect
Answer: Broncho-dilatationExplanation:Endothelin-1 is a 21 amino acid peptide produced by vascular endothelium.Function of Endothelin-1:Vasoconstriction
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Cardiac stimulation (Inotropic)Decrease renal blood flow and glomerular filtration rateStimulates aldosterone secretionRelease ANP
12. True about blood pressure measurement is all excepta) Cuff width should be 40% of arm circumferenceb) Diastolic blood pressure is indicated by fourth Korotkoff soundc) Small cuff measures spuriously elevated Diastolic blood pressured) Monkenberg sclerosis causes pseudo-hypertension
Answer: Diastolic blood pressure is indicated by fourth Korotkoff sound
AIIMS NOV 20071. Sertoli cells in the testis have receptors for:a) FSHb) LHc) Inhibind) Progesterone
Answer: FSH
2. Bicarbonate is maximally absorbed in:a) PCTb) DCTc) Collecting ductd) Thick ascending loop of Henle
Answer: PCT
3. Which of the following is correctly matched?a) B cells-Somatostatinb) D cells-Glucagonc) G cells- Gastrind) A Cells-Insulin
Answer: G cells- Gastrin
4. Following change is noted during exercise:
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a) Increased blood flow to the muscles after half minute of exerciseb) Increase in cerebral blood flow due to increase in systolic blood pressurec) Body temperature increasesd) Lymphatic flow from muscle decreases
Answer: Body temperature increases
5. In a normal person, which of the following occurs when he changes to supine position from standing?a) Cerebral perfusion increaseb) Heart rate settles to a higher levelc) Immediate increase in venous returnd) Decreased perfusion to apex
Answer: Immediate increase in venous return
6. The mechanism of action of surfactant is:a) Breaks the structure of water in the alveolib) Lubricates the flow of CO2 diffusionc) Makes the capillary surface hydrophilicd) Binds O2
Answer: Breaks the structure of water in the alveoli
7. About myocardial O2 demand, true is:a) Inverse relation with heart rateb) Directly proportional to mean arterial pressurec) Inverse relation to cardiac workd) Has a constant relation to the external work done by the heart
Answer: Directly proportional to mean arterial pressure
8. All of the following occur when the increased blood flows through systemic capillaries except:a) Increase in hematocritb) Oxygen dissociation curve shifts to the leftc) Increased protein contentd) Decrease in pH
Answer: Oxygen dissociation curve shifts to the left
9. Regarding nitric oxide, false is:
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a) Present in low concentration in cigarette smokersb) Important role in penile erectionc) Helps to regulate vascular toned) Acts through cAMP
Answer: Acts through cAMP
10. Which of the following is not true about CSF?a) Removable of CSF during dural tap causes intense intra-cranial headacheb) Normally contain no neutrophilsc) Formed by arachnoid villid) CSF pH less than plasma
Answer: Formed by arachnoid villi
AIIMS MAY 20091. Rods & Cones are differ in all excepta) Light Sensitivityb) Wavelengthb) Acuityd) Signal Transduction
Answer: Signal Transduction
2. Somatomedin mediatesa) Lipolysisb) Gluconeogenesisc) Glucose taken up by cellsd) Deposition of chondroitin sulfate
Answer: Deposition of chondroitin sulfate
3. Muscle spindle detectsa) Muscle Lengthb) Muscles tensionc) Muscle stretchb) Proprioception
Answer: Muscle Length
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4. High affinity of fetal Hb for O2 due to:a) Decreases 2, 3 DPGb) Reduced pHc) Increase releases of CO2d) Oxygen dissociation curve is shifted to right
Answer: Decreases 2, 3 DPG
5. Estrogens action on carbohydrate metabolisma) Increase uptake of glucose through increase in insulin sensitivityb) Glycolysis increasec) Increasing central adipose depositiond) Worsening of NIDDM
Answer: Increase uptake of glucose through increase in insulin sensitivity
6. Capacitance of sperm takes place in:a) Seminiferous tubulesb) Epididymisc) Vas deferenced) Uterus
Answer: Uterus
7. Not done by insulina) Glycogen synthesisb) Glycolysisc) Lipogenesisd) Ketogenesis
Answer: Ketogenesis
8. True about spinocerebellar tract is:a) Equilibriumb) Smoothens and coordinates movementc) Learning induced by change in vestibulo-ocular reflexd) Planning and programming
Answer: Smoothens and coordinates movement
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10. Maximum potassium ions secretion is seen ina) Salivab) Gastric secretionc) Jejunal secretiond) Colonic secretion
Answer: Saliva
11. Cortical representation of body in the cerebrum isa) Horizontalb) Verticalc) Tandemd) Oblique
Answer: Vertical
12. For color vision, which is true?a) Independent of wavelength of lightb) Dependents on intensity discriminationc) Involves opponent color cellsd) Minimum at fixation point
Answer: Involves opponent color cells
13. Physiological response to smoking, are all except:a) Decreased HDLb) Increase hematocritc) Decreased carboxy-hemoglobind) Increase heart rate and increase catecholamine release
Answer: Decreased carboxy-hemoglobin
AIIMS NOV 2009:1. Highest concentration of potassium is seen in?a) Bileb) Pancreatic juicec) Ileal secretionsd) Rectum
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Answer: Rectum (?)
2. Substance P is released in response to pain in periphery by?a) Endotheliumb) Mast cellsc) Nerve terminalsd) Plasma
Answer: Nerve terminals
3. Transection at the level of mid pons leads to?a) Hyperventilationb) Asphyxiac) Apnead) Rapid and shallow breathing
Answer: Apnea
4. Pacemaker regulating rate of respirationa) Pneumotaxic centreb) Dorsal group of nucleusc) Pneumotaxic centred) Pre-Botzinger complex
Answer: Pre-Botzinger complex
AIIMS MAY 20101. Intrinsic factor of Castle is secreted bya) Chief cellsb) Parietal cellsc) Mucous cellsd) Beta cells
Answer: Parietal cells
2. The main cause of increased blood flow to exercising muscles isa) Raised blood pressureb) Vasodilatation due to local metabolitesc) Increased sympathetic discharge to peripheral vessels
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d) Increased heart rate
Answer: Vasodilatation due to local metabolites
3. Appetite stimulated by all excepta) Agouti related peptideb) Melanocyte concentrating hormonec) Melanocyte stimulating hormoned) Neuropeptide Y
Answer: Melanocyte stimulating hormone
4. True about spinocerebellar tract is:a) Equilibriumb) Smoothens and coordinates movementc) Learning induced by change in vestibulo-ocular reflexd) Planning and programming
Answer: Smoothens and coordinates movement
5. Capacitance of sperm takes place in:a) Seminiferous tubulesb) Epididymisc) Vas deferenced) Uterus
Answer: Uterus
6. Somatomedin mediates:a) Deposition of chondroitin sulfateb) Lipolysisc) Gluconeogenesisd) Decreased rate of glucose uptake by cells
Answer: Deposition of chondroitin sulfate
7. Not done by insulina) Glycogen synthesisb) Glycolysisc) Lipogenesis
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d) Ketogenesis
Answer: Ketogenesis
8. Hyper-aldosteronism is associated with all except:a) Hyper-natremiab) Hypo-kalemiac) Hypertensiond) Metabolic acidosis
Answer: Metabolic acidosis
AIIMS NOV 20101. A man is given continuous testosterone. It would lead toa) Azoospermiab) Increased sperm motilityc) Increase spermatogenesisd) Increased Gonadotropins
Answer: Azoospermia
2. Cyanosis in trauma is interpreted asa) Early sign of hypoxiab) Late sign of hypoxiac) Absence of cyanosis means adequate tissue ventilationd) Absence of cyanosis means adequate tissue oxygenation
Answer: Late sign of hypoxia
3. About neuro-peptide Y all are true excepta) Contain 36 amino acid residuesb) Its level decreases during starvationc) Decrease thermogenesisd) It is mediated through melanocorticotropin hormone
Answer: Its level decreases during starvation
4. Which of the following is produced by stomach and has role in control of food intake?a) Ghrelinb) Insulin Like Growth Hormone-I
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c) Orexind) Cholecystokinin
Answer: Ghrelin
5. Not absorbed from the PCTa) Na+b) Phosphatec) HCO3-d) H+
Answer: H+
6. Negative intra-pleural pressure is due toa) Uniform distribution of surfactantb) Negative intra-alveolar pressurec) Absorption by lymphaticsd) Presence of cartilage in upper airway
Answer: Absorption by lymphatics
7. Pacemaker regulating the rate of respirationa) Pneumotaxic centreb) Dorsal group of nucleusc) Apneustic centred) Pre-Botzinger Complex
Answer: Pre-Botzinger Complex
8. Co2 diffuses more easily through the respiratory membrane than o2 because it isa) Less denseb) More soluble in plasmac) Less molecular weightd) Less PCO2 in the alveoli
Answer: More soluble in plasma
9. Not a stimulus for normal or resting ventilation?a) Stretch receptorsb) J receptors
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c) PO2d) PCO2
Answer: J receptors
10. Hypoxemia independent ofa) Altitudeb) PaCO2c) Hbd) FiO2 (Fractional O2 content)
Answer: Hb
11. Gas used to measure the diffusion capacity of lunga) COb) NOc) CO2d) Nitrogen
Answer: CO
12. Which of the following is not permeable through the blood brain barrier?a) Waterb) Gasc) Proteinsd) Lipophilic drugs
Answer: Proteins
AIIMS MAY 20111. True regarding animals that are chronically exposed to cold?a) Increased sympathetic stimulationb) Increased vagal actionc) Increased insulin levels in bloodd) Decrease blood supply to adipose tissue.
Answer: Increased sympathetic stimulation
2. True about shunt vessels:a) Evenly distributed throughout the skin
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b) Role in nutritionc) Play a role in thermoregulationd) No automatic nervous regulation
Answer: Play a role in thermoregulation
3. Vasomotor centre of medulla is associated with?a) Acts with the cardio-vagal centre to maintain B.P.b) Independent of cortico-hypothalamic inputsc) Influenced by baro-receptors not chemo-receptorsd) Essentially silent in sleep
Answer: Acts with the cardio-vagal centre to maintain B.P.
4. Energy expenditure in resting state depends ona) Lean body massb) Adipose tissuec) Resting heart rated) Exercise
Answer: Lean body mass
5. The primary direct stimulus for excitation of central chemo-receptors regulating ventilation is?a) Increased H+b) Increased CO2c) Increased O2d) Decreased CO2
Answer: Increased H+
6. True regarding myocardial O2 demand?a) Inversely related to heart rateb) Has constant relation to external cardiac workc) Directly proportional to duration of systoled) Negligible at rest
Answer: Has constant relation to external cardiac work
7. Angiotensin II causes all of the following except:a) Stimulation of thirst
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b) Aldosterone secretionc) Increased ADH SECRETIONd) Vasodilatation
Answer: Vasodilatation
8. Maximum postprandial motility is seen in:a) Ascending colonb) Transverse colonc) Descending colond) Sigmoid colon
Answer: Sigmoid colon (?)
9. CSF pressure is mainly regulated by:a) Rate of CSF formationb) Rate of CSF absorptionc) Cerebral blood flowd) Venous pressure
Answer: Rate of CSF absorption
10. Which of the following statement is true?a) Fluid coming from the descending limb of loop of Henle is hypotonicb) Descending limb of Henle is permeable to solutec) If clearance of a substance is greater than GFR, then tubular secretion must be presentd) Clearance of a substance is always more than GFR if there is tubular secretion
Answer: If clearance of a substance is greater than GFR, then tubular secretion must be present
11. Nitrogen narcosis is caused due to:a) Nitrogen inhibits dismutase enzymeb) Increase production of nitrous oxidec) Increase solubility of nitrogen in nerve cell membraned) Decrease in oxygen free radicals
Answer: Increase solubility of nitrogen in nerve cell membrane
AIIMS NOV 2011 1 Which of the following is not the primary function of gut flora?
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a) Synthesis of short chain fatty acidsb) Increased proliferation of epithelial cellsc) Production of vitamin kd) Fermentation of mucin
Answer: Fermentation of mucin
2. Tidal volume excessive load is prevented by activation of which of the following receptors:a) J receptorsb) Thoracic muscle spindlec) Bronchial stretch receptorsd) Arterial baro-receptor
Answer: Bronchial stretch receptors
3. Adrenaline, nor-adrenaline and dopamine act through:a) Single pass receptorb) Four pass receptorc) Seven pass receptord) Ligand gated receptor
Answer: Seven pass receptor
4. Nobel Prize for sequencing insulin structure was given to:a) Banting and Macleodb) Sangerc) Charles Bestd) Paul Berg
Answer: Sanger
2. Mean arterial pressure is calculated as:a) (SBP + 2DBP)/3b) (DBP + 2SBP)/3c) (SBP + 3DBP)/2d) (DPB + 3SBP)/2
Answer: (SBP + 2 DBP)/3
AIIMS MAY 2012
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1. CSF pressure is mainly regulated bya) Rate of CSF formationb) Rate of CSF absorptionc) Cerebral Blood Flowd) Venous Pressure
Answer: Rate of CSF absorption
2. On exposure to cold, a neonate shows all of the following mechanism for heat production EXCEPT:a) Shiveringb) Crying and flexion of body like fetus positionc) Cutaneous Vasoconstrictiond) Increased production of Nor-adrenaline for breakdown of brown fat in adipose tissue
Answer: Shivering
3. Without external cues, the sleep-wake cycle in humans:a) Does not continueb) Continue with cycle length of 24 hoursc) Continue with cycle length of less than 24 hoursd) Continue with cycle length of more than 24 hours
Answer: Continue with cycle length of 24 hours
4. All of the following are true for ADH, excepta) Post-operative increase in secretionb) Neuro-secretionc) Increased secretion when plasma osmolality is lowd) Act on distal tubule and increase permeability
Answer: Increased secretion when plasma osmolality is low
5. Critical Closing volume isa) Volume at the end of forceful expirationb) Volume at the end of forceful inspirationc) Volume remaining after Functional Residual Capacity is measuredd) Close to Residual Volume
Answer: Close to Residual Volume
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6. During moderate exercise, blood flow to braina) Increasesb) Decreasesc) No effectd) First increases then decrease
Answer: No effect
7. Ventricular Depolarization starts froma) Postero-basal part of ventricleb) Basal part of ventriclec) Uppermost part of Inter-ventricular septumd) Left part of Inter-ventricular septum
Answer: Left part of Inter-ventricular septum
8. Left lobe is responsible fora) Appreciation of Musicb) Spatial orientationc) Fine Motor Movement / Visual Stimuli Processingd) Written and Spoken Language
Answer: Written and Spoken Language
AIIMS NOV 20121. All are second messenger excepta) Cyclic AMPb) IP3c) Guanylyl cyclased) DAG
Answer: Guanylyl cyclase
2. All are true regarding blood supply increase in muscles during exercise, excepta) Local metaboliteb) Increased arterial pressurec) Cholinergic stimulationd) Decreased beta adrenergic stimulation
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Answer: Decreased beta adrenergic stimulation
3. End diastolic volume increases due toa) Decrease in total blood volumeb) Increase in intra-pericardial pressurec) Increase in negative intra-thoracic pressured) Decrease in ventricular compliance
Answer: Increase in negative intra-thoracic pressure
4. Clamping of carotid artery below the carotid sinus is likely to producea) Increase in vasomotor centre activityb) Increase in discharge of carotid sinus afferent nerves c) Increase in vagal parasympathetic activityd) Baro-receptor adaptation
Answer: Increase in vasomotor centre activity
5. Self stimulation could be induced experimentally most effectively from which part of brain?a) Medial forebrain bundleb) Area around aqueduct of sylviusc) PV region of hypothalamusd) Mesencephalon
Answer: Medial forebrain bundle
6. Kinemyograhy is used for:a) Monitoring of neuromuscular functionb) Monitoring of muscle spindle activityc) Monitoring of exercise capacityd) Monitoring of depth of anesthesia
Answer: Monitoring of neuromuscular function
7. A politician is shot in the back during a rally at level of T8 vertebra .immediately after the shot he loses allthe sensation below level of lesion.No recovery is noted even after proper treatment. All of the following are the possible reason for his non-recovery, excepta) Lack of endo-neural tubesb) Lack of growth factors
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c) Presence of glial scard) Lack of myelin inhibiting substance
Answer: Lack of myelin inhibiting substance
AIIMS MAY 20131. Most common end product of progesterone metabolism found in urine isa) Pregnanetriolb) Pregnanediolc) Pregnenoloned) 17-hydroxy-Pregnenolone
Answer: PregnanediolExplanation:Progesterone is a C21 steroid secreted by the corpus luteum, the placenta and the follicle (in smallamount).Progesterone is nearly completely degraded in liver. The major product of degradation is Pregnanediolwhich is excreted in urine as glucuronide and sulfate conjugates.
2. Which of the following is the true for the pulmonary neuro-endocrine cells?a) Contain Catecholaminesb) Contain serotoninc) Have only cholinergic nerve supplyd) Respond to a decrease in Po2
Answer: Contain serotonin and Respond to a decrease in Po2
3. Fick’s law of diffusion explainsa) Active diffusion along concentration gradientb) Passive diffusion along concentration gradientc) Both of thesed) None of these
Answer: Passive diffusion along concentration gradient
4. In a normal person, which of the following occurs when he changes to supine position from standing?a) Cerebral perfusion increaseb) Heart rate settles to a higher levelc) Immediate increase in venous return
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d) Decreased perfusion to apex
Answer: Immediate increase in venous return
5. Release of synaptic vesicles from the pre-synaptic terminals is inhibited by?a) Preventing depolarization of nerve impulseb) Inhibition of conduction of nerve impulsec) Prevention of Ca2+ influxd) Prevention of Na+ influx
Answer: Prevention of Ca2+ influxExplanation:
6. A cell membrane is damaged by insertion of micro-needle, repair shall occur by which of the followingprocess?a) Lateral movement of proteinsb) Resealing by lipid bi-layerc) Enzymatic reactiond) Hydrophobic interaction
Answer: Resealing by lipid bi-layer
7. Cyanosis does not develop in severe anemia because ofa) It requires critical concentration of reduced hemoglobin in blood.b) In anemia, the blood flow through the skin is decreased.c) In anemia, the hemoglobin has greater oxygen carrying capacity per unit gram of hemoglobin.d) Due to decreased oxygen carrying capacity of blood
Answer: It requires critical concentration of reduced hemoglobin in blood.
8. Which of the following statements is true about ESR in tuberculosis?a) ESR confirms recovery from TBb) ESR remains normalc) ESR value are increased due to decrease in size of the RBCsd) ESR values are increased due to formation of larger aggregates of RBCs
Answer: ESR value are increased due to decrease in size of the RBCs
AIIMS NOV 20131. Blood testis barrier is between
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a) Sertoli and Sertoli cellsb) Leydig and Myoid cellsc) Sertoli and Germ cellsd) Sertoli and Spermatid
Answer: Sertoli and Sertoli cells
2. Trans-cutaneous nerve stimulation to relieve pain acts bya) Gate way theory of painb) Central painc) Allodyniad) Referred pain
Answer: Gate way theory of pain
3. Fertilized ovum reaches the uterine cavity ina) 7-8 daysb) 6-7 daysc) 5- 6d) 3-4 days
Answer: 3-4 days
6. Metabolite of progesterone in urine isa) Pregnanediolb) 17-OH Progesteronec) Pregnanetriold) 17 Keto-steroid
Answer: Pregnanediol
AIIMS MAY 20141. True about Nuclear bag fibersa) Sense dynamic length of muscleb) Involved in reciprocal innervationc) Alpha motor neuron stimulationd) Senses muscle tension
Answer: Sense dynamic length of muscle
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2. Receptor of joint capsule and ligaments isa) Slow adaptingb) Fast adaptingc) Different to slow and fast adaptingd) Non-adapting
Answer: Slow adapting
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Filed in: AIIMS: 2001-14, I. PHYSIOLOGY, PHYSIOLOGY: AIIMS
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Shahjad Khan · Works at Nursing tutorsuperReply · Like · August 6 at 7:59pm