wpbph1 ws2017-18 nr03 (30.10.2017).ppt - kompatibilitätsmodus · kirchhoff-institut für physik...
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Kirchhoff-Institut für Physik
Prof. Dr. Petrich Biophotonics I (WS 2017/18) 1
Biophotonics IW. Petrich
Slides of lecture #03 October 30th, 2017
http://www.kip.uni-heidelberg.de/biophotonik/teaching
• Lecture „Biophotonics I“ will be credited with 2 CP subject to successfully passing the exam
• There will be a written exam („Klausur“) on February 5th, 2018
• registration: https://uebungen.physik.uni-heidelberg.de/v/831
Kirchhoff-Institut für Physik
Biophotonics ISUMMARY of lecture#2 (23.10.2017)
spherical aberration
Petzval field curvature
comachromatic aberration
astigmatism
Pictures taken from: W.W. Charman, „Vision and visual dysfunction“ (1991); wikipedia.de; itiv.uni-karlsruhe.de;childrenshospital.org; scien.stanford.edu
C) point spread function (PSF)I.1.3.B) diffraction at the iris (cont‘)
'')'()'()','(
'')'()'()','(
),(),(
dydxyyxxLyxf
dydxyyxxyxfL
yxfLYXg
(for incoherent illumination) the PSF is the image of a -function
D) aberration
1
)~,~()~,~(')~,~(i
ii yxcyxQQnyxW
e.g. Zernike polynoms
1 2 3 4 5 6 7 8
1
2
3
visu
s
diameter of pupil [mm]
100%
detecting aberration
• cornea• videokerato-
graphy• Scheimpflug method
• eye• Tscherning aberrometer• ray tracing sensor• Shack-Hartmann sensor
Prof. Dr. Petrich Biophotonics I (WS 2017/18) 2
Kirchhoff-Institut für Physik
Biophotonics I“refractive errors” of the human eye
myopia hyperopia
Prof. Dr. Petrich Biophotonics I (WS 2017/18) 3
temporal
nasal
presbyopia
Kirchhoff-Institut für Physik
Prof. Dr. Petrich Biophotonics I (WS 2017/18) 4
Biophotonics II.1.4.sensors for human vision
From: • H. Kolb, R. Nelson, E. Fernandez, E. Jones, „Webvision“• H. Gross (Ed.), „Handbook of Optical Systems, Vol 4: Survey of
Optical Instruments“, VCH-Wiley 2008
Biophotonics Isensors for human vision
Kirchhoff-Institut für Physik
Prof. Dr. Petrich 5
From: H. Kolb, R. Nelson, E. Fernandez, E. Jones, „Webvision“
Biophotonics Isensors for human vision
Biophotonics I (WS 2017/18) Prof. Dr. Petrich 5
Kirchhoff-Institut für Physik
Prof. Dr. Petrich 6
From: Stevens, Alan ; Lowe, James: Histologie. 1. Weinheim : VCH Verlagsgesellschaft, 1992. – ISBN 3–527–15511–2
Biophotonics Isensors for human vision
Biophotonics I (WS 2017/18)
From: chm.bris.ac.uk
Prof. Dr. Petrich 6
Kirchhoff-Institut für Physik
Prof. Dr. Petrich Biophotonics I (WS 2017/18) 7
Biophotonics II.1.4. sensors for human vision
From: J.M. Berg, J.L. Tymoczko, L. Stryer, Biochemie“, Spektrum Akad. Verlag, Heidelberg
Kirchhoff-Institut für Physik
Prof. Dr. Petrich Biophotonics I (WS 2017/18) 8
Biophotonics II.1.4. sensors for human vision
From: J.M. Berg, J.L. Tymoczko, L. Stryer, „Biochemie“, Spektrum Akad. Verlag, Heidelberg
Kirchhoff-Institut für Physik
Prof. Dr. Petrich Biophotonics I (WS 2017/18) 9
Biophotonics II.1.4. sensors for human vision
Kirchhoff-Institut für Physik
Prof. Dr. Petrich Biophotonics I (WS 2017/18) 10
Biophotonics II.1.4. sensors for human vision
From: chm.bris.ac.uk
Kirchhoff-Institut für Physik
Prof. Dr. Petrich Biophotonics I (WS 2017/18) 11
Biophotonics II.1.4. sensors for human vision
From: chm.bris.ac.uk
Kirchhoff-Institut für Physik
Prof. Dr. Petrich Biophotonics I (WS 2017/18) 12
Biophotonics II.1.4. sensors for human vision
From: papoian.chem.umd.edu
Kirchhoff-Institut für Physik
Prof. Dr. Petrich Biophotonics I (WS 2017/18) 13
Biophotonics II.1.4. sensors for human vision
From: H. Kolb, R. Nelson, E. Fernandez, E. Jones, „Webvision“
Fig. 10. Activation of Rhodopsin by light and the phototransduction cascade. Light transduces the visual pigment via the following enzyme cascade: photons – rhodopsin – activated rhodopsin (R*) (metarhodopsin II) – �a GTP binding protein ( Tα*)(transducin) – an enzyme hydrolyzing cGMP (cGMP-phosphodiesterase, PDE*) – closes a membrane bound cGMP-gated cation channel (lower right). Courtesy of Wolfgang Baehr.