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Winter/Spring 2017

Forewords from the Head Dear DoCS:

After walking around the buildings today on my “circle walk”, I remembered once again why I love North Carolina. It was a picture perfect day. We have lots to be grateful for in our Department: another successful school year, research successes, a clinic that continues to hum along and ice cream at the End-of-the-Year Celebration that wasn’t rock hard solid.

We added new faculty (see Ashley’s list below) and we have even more coming soon. Dentistry and ECC will be fully staffed! We have had some nibbles in our search for a new soft Tissue surgeon. I’ve heard many plans for implementing techniques that follow the guidelines in “Make it Stick”. Tophat has been approved as the official audience response system for the University, so our department is ahead of the game as clickers go away. I know those of you who have suffered flooding and worse during the renovations of the third floor labs can’t wait to see the construction finished. For those who are displaced, moving day is near! The Clinical Studies Core is rebuilding under Eleanor Hawkins’ steady hand and is busy, busy, busy. The MRI at CMAST has actually produced readable images due to Michael Stoskopf’s faith and persistence. Metabolomics, here we come. On the clinical side, I wish you a manageable July 4th. I will try to get my neighbors to crate their dogs during the fireworks so you won’t have to see me dragging in a Trinity Rd/I 440 casualty. Last year was way too close for my comfort, with both of their dogs leaping the fence during the predictable 9 pm boom fest. I want to publically thank Ashley for all her hard work for the department. She will stay on as a temp to get us through dossier building, but then she has a little girl coming, who will need tending. Take time to enjoy the outdoors this summer, Lizette

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Faculty & Staff Updates Awards/Congratulations Grants Books & Papers In the News Postdoc, Graduate Student

& Resident News Personal News Who Am I Other News and Updates

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Faculty & Staff Updates New Employees Dr. Olivia Petritz – Assistant Professor of Avian-Exotic Animal Medicine – January 4, 2017 Dr. Joanne Intile – Clinical Assistant Professor of Medical Oncology – February 6, 2017 Corey Moore – Research Specialist (Clinical Studies Core)– February 26, 2017 Brianna Johnson - Clinical Studies Core Clinical Operations Manager – April 19, 2017 Dr. Curtis Stiles – Clinical Assistant Professor of Dentistry and Oral Surgery – April 28, 2017k Sheldon Perry – Research Assistant (Harms Lab) – May 22, 2017 Dr. Nimet Browne – Clinical Assistant Professor of Equine Internal Medicine – July 1, 2017 Dr. Lenin Villamizar-Martinez – Assistant Professor of Dentistry and Oral Surgery – July 8, 2017 Dr. Alex Lynch – Assistant Professor of Emergency and Critical Care – July 10, 2017

Departing Faculty and Staff Beth Case (CVM employee since April 1987) – December 31, 2016 Janet Bogan – January 4, 2017 Kim Williams – January 6, 2017 Stan Dunston – retired April 1, 2017 Nandhakumar Balakrishnan (post doc) – April 14, 2017 Jacqueline Whittenburg – April 27, 2017 Barbara Hegarty – retired May 31, 2017 Dr. Marije Risselada – July 7, 2017 Faculty Recruitment Updates We will re-open the recruitment for a tenure track Assistant/Associate Professor of Medical

Oncology in Fall 2017. We are currently recruiting for a tenure track Assistant Professor in Small Animal Soft Tissue and

Oncology Surgery. The position is posted. _ _ _ _ _ _ _ _ _ _

Awards/Congratulations (December 2016 - May 2017) Dr. Blikslager received the 1) Alumni Association Distinguished Graduate Professorship Award, 2) the Huffman Leadership Award, and 3) the R. G. Thomson Lectureship Award from the Atlantic Veterinary College, University of Prince Edward Island, Canada. Dr. Breitschwerdt received the 2017 American Association of Veterinary Medical Colleges Research Award. Dr. Gilger received the 2017 Distinguished Alumni Award from Ohio State University. Dr. Hardie received the Zoetis Distinguished Teaching Award. Dr. Harrison was inducted into the Michigan State University’s Farm Lane Society.

Dr. Lascelles received the 2017 AVMF / Winn Feline Foundation Research Award. Dr. Sheats received a Morris Animal Foundation Established Investigator Award.

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Grants Received (December 2016 - May 2017) Bizikova P, Olivry T (co-PI). An alternative to long-lasting elimination diets for the diagnosis of food allergy in dogs with atopic dermatitis. 2017. Royal Canin, Aimargues, France ($22,458). Lascelles BDX. A Pilot Dose Confirmation Study to Evaluate the Effectiveness and Safety of Intraarticular Injection of CNTX4975 for the Control of Pain Associated with Osteoarthritis in Dogs. Centrexion 01/01/2017-12/31/2017 $44,218

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Lascelles BDX. Proteomic evaluation of feline serum samples from cats with chronic Kidney disease (CKD), degenerative joint disease (DJD) or both CKD and DJD. Collaboration between Dr. Duncan Lascelles (NCSU) and [Industry]. 01/01/2017-12/31/2017 $0 (assays valued at $350,000) Lascelles BDX. Evaluation of XXX Monitoring Collar for Dogs. Industry 01/01/2017-06/30/2018 $127,867 Mariani CL, Fogle JE. Immunosuppression in malignant canine gliomas: a unique, naturally occurring model of human disease and prelude to immunotherapy in both species. Comparative Medicine Institute Summer Interdisciplinary Research Initiative (SIRI) Grant, North Carolina State University, 2016. $8,000. Olivry T. Allergic disease treatment with a novel anti-IgE chimeric protein. 2017-2018. NC State University Chancellor’s Innovation Fund ($73,310). Olivry T, Baeumer W. Testing of novel anti-allergic drugs in an acute atopic dog model. 2016-2017. Merial, Inc., Duluth, Georgia ($202,653). B. Qurollo, William Pan (PI), Micheal Levy, Roland Kays, Charles Nunn, Maggie Skiles, Justin Lana. Untangling human-animal transmission of cutaneous leishmanaisis. Funded by NCSU-Researcg Innovation Seed Funding, NCSU-Comparative Medicine Institute, and matching funds Mike Levy. January 2017.

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Books and Papers Published (December 2016 - May 2017) Adin D, Atkins C, Papich M, DeFrancesco T, Griffiths E, Penteado M, Kurtz K, Klein A. Furosemide continuous rate infusion diluted with 5% dextrose in water or hypertonic saline in normal adult dogs: a pilot study. J Vet Cardiol. 2017:19(1):44-56.

Applegate JR, Drapp RL, Lewbart GA. Nonfatal Traumatic Gastric Evisceration in Two Box Turtles (Terrapene carolina carolina). JHMS

Applegate, Jr JR, Dombrowski DS, Christian LS, Bayer MP, Harms CA, Lewbart GA. 2016. Tricaine methanesulfonate (MS-222) sedation and anesthesia in the purple-spined sea urchin (Arbacia punctulata). J Zoo Wildl Med 47: 1025-1033. http://dx.doi.org/10.1638/2015-0288.1 Bäumer W, Bizikova P, Jacob M, Linder KE. Establishing a canine superficial pyoderma model. Journal of Applied Microbiology 2017 Feb; 122(2): 331-337. Fogle J, Jacob M, Blikslager A, Edwards A, Wagner B, Dean K, and Fogle C. Comparison of lipopolysaccharides and soluble CD14 measurement between clinically endotoxaemic and nonendotoxaemic horses. Equine Vet J. 2017 Mar; 49(2):155-159 Shrauner B, Blikslager AT, Davis J, Campbell N, Law M, Lustgarten M, Prange T. Feasibility and safety of lumbosacral epiduroscopy in the standing horse. Equine Vet J. 2017;49:322-328 Shelnutt LM, Balakrishnan N, DeVanna J, Batey KL, Breitschwerdt EB. Death of Military Working Dogs Due to Bartonella vinsonii Subspecies berkhoffii Genotype III Endocarditis and Myocarditis. Mil Med. 2017

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Mar;182(3):e1864-e1869. doi: 10.7205/MILMED-D-16-00125 Hensley MT, Tang J, Woodruff K, DeFrancesco T, Tou S, Williams CM, Breen M, Meurs K, Keene B, Cheng K. Intracoronary allogeneic cardiosphere-derived stem cells are safe for use in dogs with dilated cardiomyopathy. J Cell Mol Med 2017. DOI:10.1111/jcmm.112632. Fenn J, Laber E, Williams K, Rousse CA, Early PJ, Mariani CL, Munana KR, De Decker S, Volk HA, Olby NJ. (2017) Associations between anesthetic variables and functional outcome in dogs with thoracolumbar intervertebral disk extrusion undergoing decompressive hemilaminectomy. Journal of Veterinary Internal Medicine, Epub before print. doi: 10.1111/jvim.14677 Elfenbein JR, Knodler LA, Schaeffer AR, Faber F, Bäumler AJ, Andrews-Polymenis HL. A Salmonella Regulator Modulates Intestinal Colonization and Use of Phosphonoacetic Acid. Frontiers in Cellular and Infection Microbiology. 2017;7(69). doi: 10.3389/fcimb.2017.00069. Ziegler A, Fogle C, Blikslager A. Update on the use of cyclooxygenase-2-selective nonsteroidal anti-inflammatory drugs in horses. J Am Vet Med Assoc. 2017 Jun 1;250(11):1271-1274. doi: 10.2460/javma.250.11.1271. PubMed PMID: 28509650. Gieger TL, Nettifee-Osborne J, Hallman B, Johannes C, Clarke D, Nolan MW, Williams LE.. The impact of carboplatin and toceranib phosphate on serum VEGF and MMP-9 levels and survival in canine osteosarcoma. Canadian Journal of Veterinary Research. Accepted, December 2016. Smith SM, Salmon JH, Abbaraju S, Amin R, Weiss S, Grau U, Velagaleti P, Gilger B. Evaluation of pentablock co-polymer (PTSsol) for sustained topical ocular delivery. Journal of Drug Delivery Science and Technology 2017 (In Press) Schaefer E, Smith S, Salmon J, Abbaraju S, Amin R, Weiss S, Grau U, Velagaleti P, Gilger B. Evaluation of intracameral pentablock co-

polymer thermosensitive gel (PTSgel) for sustained drug delivery to the anterior chamber of the eye. J Ocular Pharm Therapeutics 2017 (doi: 10.1089/jop.2016.0181) Kruger L, Gonzalez LM, Pridgen TA, McCall SJ, von Furstenberg R, Harnden I, Carnighan GE, Cox AM, Blikslager AT, Garman KS. Ductular and proliferative response of esophageal submucosal glands in a porcine model of esophageal injury and repair. American journal of physiology Gastrointestinal and liver physiology Article in Press, 2017. Cannizzo SA, Rick M, Harrison TM, Harms CA. 2017. Parathyroid hormone, ionized calcium, and 25-hydroxyvitamin D concentrations in the domestic ferret (Mustela putorius furo). J Exotic Pet Med, in press. Harrison TM, Harrison SH. Evaluation of morbidity and mortality in lesser hedgehog tenrecs (Echinops telfairi). Journal of Zoo and Wildlife Medicine. 2017. In press. Thompson KA, Agnew D, Harrison TM. Case series of obstetrical and post-partum complications in lesser Madagascar hedgehog tenrecs (Echinops telfairi). Journal of Zoo and Wildlife Medicine. 2017. In press. Thompson KA, Patterson J, Kitchell B, Harrison TM. Case series of renal carcinoma in a family of binturong (Arctictis binturong) including treatment with pyelonephrectomy and a tyrosine kinase inhibitor. Journal of Zoo and Wildlife Medicine. 2016. 47(4): 1109–1113. Schlanser JR, Bohart GW, Paperd DW, Wagner C, Marquardt M, Harrison TM. Technique for venipuncture of the facial vein in black rhinoceros (Diceros bicornis). 2016. Zoo Biology. Nov/Dec. 35(6). 579-573. Brady S, Harrison TM, Rodriguez C, Wack RF. Intralesional bleomycin to treat oral squamous cell carcinoma in a greater hedgehog tenrec (Setifer setosus). Veterinary Record Case Reports. 2016. Kedrowicz AA, Hammond S, Dorman D. Improving Students’ Email Communication through an Integrated Writing Assignment in a Third-Year Toxicology Course. Journal of

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Veterinary Medical Education, 2017 44(2), 280-289. Carter J, Krug W, Griffiths E, Keene B. The Effect of Heart Disease on Anesthetic Complications During Routine Dental Procedures in Dogs. J Am An Hosp Assoc, April 15, 2017. Ward JL, Lisciandro GR, Keene BW, Tou SP, DeFrancesco TC. Accuracy of point-of-care lung ultrasonography for the diagnosis of cardiogenic pulmonary edema in dogs and cats with acute dyspnea. J Am Vet Med Assoc. 2017 Mar 15;250(6):666-675 Cannizzo S, Stinner M, Kennedy-Stoskopf S. Prevalence of cystinuria in servals (Leptailurus serval) in the United States. 2017. Accepted JZWM. Johnson RJ, Kerr CL, Enouri SS, Modi P, Lascelles BD, del Castillo JR. Pharmacokinetics of liposomal encapsulated buprenorphine suspension following subcutaneous administration to cats. J Vet Pharmacol Ther. 2017 Jun;40(3):256-269. doi: 10.1111/jvp.12357. Epub 2016 Sep 20. PMID:27647259 Walton B, Innes JF, Lascelles BD. Validated Outcomes Measures for Canine Osteoarthritis. Vet Surg. 2017 Apr;46(3):341-342. doi: 10.1111/vsu.12636. PMID: 28314073 Gruen ME, Dorman D, Lascelles BDX. Caregiver Placebo Effect in Analgesic Clinical Trials for Painful Cats with Naturally-Occurring Degenerative Joint Disease. Vet Rec. 2017 Mar 7. pii: vetrec-2016-104168. doi: 10.1136/vr.104168. [Epub ahead of print] PMID: 28270539 Oviedo-Rondón, Edgar; Lascelles, B. Duncan X.; Arellano, Consuelo; Mente, Peter; Eusebio-Balcazar, Pamela; Grimes, Jesse; Mitchell, Alva. Gait parameters in four strains of turkeys and correlations with bone strength. Poult Sci. 2017 Feb 16. doi: 10.3382/ps/pew502. [Epub ahead of print] No abstract available. PMID: 28204753 Enomoto M, Lascelles BDX, Gerard MP. Defining the local nerve blocks for feline distal

pelvic limb surgery: a cadaveric study. J Feline Med Surg. 2017 Feb 1:1098612X17690652. doi: 10.1177/1098612X17690652. [Epub ahead of print] PMID: 28186424 Enomoto M, Kigin PD, Bledsoe D, Slone R, Hash J, Smith CE, Lascelles BDX. Pilot evaluation of a novel unilateral declaw model and efficacy of an extended release buprenorphine product. BMC Vet Res. 2017 Jan 24;13(1):32. doi: 10.1186/s12917-017-0943-5. PMID: 28118835 Gruen ME, Alfaro-Cordoba M, Thomson AE, Worth A, Staicu AM, Lascelles BDX. The Use of Functional Data Analysis to Evaluate Activity in a Spontaneous Model of Degenerative Joint Disease Associated Pain in Cats. PLoS One. 2017 Jan 18;12(1):e0169576. doi: 10.1371/journal.pone.0169576. PMID: 28099449 Knazovicky D, Case B, Thomson A, Helgeson E, Gruen M, Maixner W, Lascelles BDX. Trial effects and test-retest reliability of quantitative sensory threshold testing in dogs with chronic pain Vet Anaesth Analg. 2017 Jan 10. pii: S1467-2987(17)30058-2. doi: 10.1016/j.vaa.2016.08.008. [Epub ahead of print] PMID: 28528759 Gruen ME, Rishniw M, Lascelles BDX. Veterinarian attitudes toward clinical research: a survey study. J Am Vet Med Assoc. 2017 Jan 1;250(1):86-97. doi: 10.2460/javma.250.1.86. PMID: 28001115 Greene LM, Royal KD, Bradley JM, Lascelles BD, Johnson LR, Hawkins EC. The Severity of Nasal Inflammatory Disease Questionnaire for Canine Idiopathic Rhinitis Control: Instrument Development and Initial Validity Evidence. J Vet Intern Med. 2016 Dec 25. doi: 10.1111/jvim.14629. [Epub ahead of print] PMID: 28019044 Gruen ME, Messenger KM, Thomson AE, Griffith EH, Vaden S, Paradise H, Lascelles BD. A Comparison of Serum and Plasma Values using a Multiplexed Cytokine asssy in Cats. Veterinary Immunology and Immunopathology. 2016 Dec;182:69-73. doi: 10.1016/j.vetimm.2016.10.003. PMID: 27863553

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Muñoz-Pérez JP, Lewbart GA, Hirschfeld M, Alarcón-Ruales D, Denkinger J, Castañeda JG, García J, Lohmann KJ. Blood gases, biochemistry and haematology of Galápagos hawksbill turtles (Eretmochelys imbricata). Conserv Physiol. 2017 May 10;5(1):cox028. doi: 10.1093/conphys/cox028. eCollection 2017. PMID: 28496982 Phillips BE, Posner LP, Lewbart GA, Christiansen EF, Harms CA. 2017. Assessment of the effects of three doses of intravenous alfaxalone on yearling loggerhead sea turtles (Caretta caretta). J Am Vet Med Assoc 250: 909-917. Cannizzo SA, Lewbart GA, Westermeyer HD. Intraocular pressure in American Bullfrogs (Rana catesbiana) measured with rebound and applanation tonometry. Vet Ophthalmol. 2017 Mar 1. [Epub ahead of print] Adamovicz, L, Trosclair, M, Lewbart GA. Biochemistry panel reference intervals for juvenile goldfish (Carrasius auratus). Accepted JZWM, January 30, 2017. Friedenberg SG, Lunn KF, Meurs KM (2016) Evaluation of the genetic basis of primary hypoadrenocorticism in Standard Poodles using SNP array genotyping and whole-genome sequencing. Mammalian Genome, 2017 Feb;28(1-2):56-65. doi: 10.1007/s00335-016-9671-6. Epub 2016 Nov 18. Smith EJ, Marcellin-Little DJ, Harrysson OLA, Griffith EH. Three-dimensional assessment of curvature, torsion, and canal flare in the dog humerus. Am J Vet Res, submitted November 2016 (AJVR-16-11-0307), accepted January 26, 2017, in press. Bertocci G, Brown NP, Marcellin-Little DJ. Canine cranial cruciate ligament deficient stifle biomechanics associated with extra-articular stabilization predicted using a computer model. Vet Surg (VSU-16-113), accepted December 16, 2016, in press. Nye CJ, Mariani CL. Validation of a portable monitor for assessment of cerebrospinal fluid lactate in dogs. 2017 In Press, Veterinary Clinical Pathology.

Mariani CL. (2017) Peripheral Neuropathies. In: Ettinger SJ, Feldman EC and Cote E (eds). Textbook of Veterinary Internal Medicine, 8th edition. Saunders Elsevier, St. Louis, MO. pp. 1451-1456. Moore SA, Mariani CL. (2017) Neuromuscular Junction Disorders. In: Ettinger SJ, Feldman EC and Cote E (eds). Textbook of Veterinary Internal Medicine, 8th edition. Saunders Elsevier, St. Louis, MO. pp. 1456-1459. Mowat FM, Gervais KJ, Occelli LM, Annear MJ, Querubin J, Bainbridge JW, Smith AJ, Ali RR, Petersen-Jones SM. Early onset progressive degeneration of the area centralis in RPE65-deficient dogs. Investigative Ophthalmology and Visual Science 2017 (accepted for publication 5/22/17) Mowat FM, Occelli L, Bartoe JT, Gervais KJ, Bruewer A, Querubin J, Dinculescu A, Boye SL, Hauswirth WW, Petersen-Jones SM. Gene Therapy in a Large Animal Model of PDE6A-Retinitis Pigmentosa. Frontiers in Neuroscience 2017 (accepted for publication 5/30/17) Zarfoss M, Tusler CA, Kass PH, Montgomery K, Lim CC, Mowat FM, Thomasy SM. Uveodermatologic syndrome in dogs: clinical findings and outcomes in 50 cases (1985-2013). Journal of the American Veterinary Medical Association 2017 Nettifee JA, Griffith EH, Muñana KR. Evaluation of the impacts of epilepsy in dogs on their caregivers. Journal of the American Animal Hospital Association, 2017 Mar 14. doi: 10.5326/JAAHA-MS-6537 [Epub ahead of print]. Nye C, Musulin SE, Hanel R, Mariani CL. Evaluation of the Lactate Plus monitor for blood lactate measurements in dogs. J Vet Emerg Crit Care 2017;25(5):679-683. Nolan MW, Long CT, Marcus K, Sarmadi S, Roback D, Fukuyama T, Baeumer W, Lascelles BDX. Nocifensive behaviors in mice with radiation-induced oral mucositis. Radiation Research. Epub ahead of print, 2017. Nolan MW, Gieger TL, Karakashian AA, Nikolova-Karakashian MN, Posner LP, Roback

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DM, Rivera JN, Chang S. Outcomes of spatially-fractionated radiotherapy (GRID) for bulky soft tissue sarcomas in a large animal model. Technology in Cancer Research & Treatment. Epub ahead of print, 2017. Nolan MW, Arkans MM, LaVine D, DeFrancesco T, Myers JA, Griffith EH, Posner LP, Keene BW, Tou SP, Gieger TL. Pilot study to determine the feasibility of radiation therapy for dogs with right atrial masses and hemorrhagic pericardial effusion. Journal of Veterinary Cardiology. In press, 2017. Berg NG, Pearce BL, Rohrbaugh N, Jiang L, Nolan MW, Ivanisevic A. Gallium containing composites as a tunable material to understand neuronal behavior under variable stiffness and radiation conditions. Materials Science and Engineering: C 71:317-321, 2017 Urkasemsin G, Nielsen D, Singleton A, Arepellia S, Hernandez D, Agler C, Olby NJ. Hereditary Ataxia in Scottish Terriers Maps to the X Chromosome. J Vet Intern Med. 2017 May 29. doi: 10.1111/jvim.14738. Lewis MJ, Howard JF, Olby NJ. The relationship between trans-lesional conduction, motor neuron pool excitability and motor function in dogs with incomplete recovery from severe spinal cord injury. Accepted by J Neurotrauma, 2017. Moore SA, Granger N, Olby NJ, Spitzbarth I, Jeffery ND, Tipold A, Nout-Lomas YS, da Costa R, Stein VM, Noble-Haeusslein LJ, Blight AR, Grossman RG, Basso DM and Levine JM. Targeting translational successes through CANSORT-SCI: using pet dogs to identify effective treatments for spinal cord injury. Consortium white paper. J Neurotrauma. 2017 Mar 22. doi: 10.1089/neu.2016.4745. Lim JH, Koh S, Thomas R, Breen M, Olby NJ. Evaluation of gene expression and DNA copy number profiles of adipose tissue-derived stromal cells and consecutive neurosphere-like cells generated from dogs with naturally occurring spinal cord injury. Am J Vet Res. 2017 Mar;78(3):371-380. doi: 10.2460/ajvr.78.3.371.

Olby NJ, Vaden SL, Williams K, Griffith EH, Harris T, Mariani CL, Muñana KR, Early PJ, Platt SR, Boozer L, Giovanella C, Longshore R. Effect of Cranberry Extract on the Frequency of Bacteriuria in Dogs with Acute Thoracolumbar Disk Herniation: A Randomized Controlled Clinical Trial. J Vet Intern Med. 2017 Jan;31(1):60-68. doi: 10.1111/jvim.14613. Epub 2016 Dec 3. Banovic F, Olivry T, Linder KE. Clinical, microscopic and microbial characterization of exfoliative superficial pyoderma-associated epidermal collarettes in dogs. Veterinary Dermatology 2017; 28: 107-e23. PMID: 27747960 Mauldin E, Wang P, Olivry T, Evans E, Casal M. Epidermolysis bullosa simplex in sibling Eurasier dogs is caused by PLEC nonsense mutation and decreased plectin expression. Veterinary Dermatology 2017; 28:10-e3. PMID: 27878870 Banovic F, Dunston SM, Linder KE, Rakich P, Olivry T. Apoptosis as a mechanism for keratinocyte death in canine toxic epidermal necrolysis. Veterinary Pathology 2017; 54:249-253. PMID: 27581387 Olivry T, Paps JS and Dunston SM. Proof of concept of the preventive efficacy of high-dose recombinant mono-allergen immunotherapy in atopic dogs sensitized to the Dermatophagoides farinae allergen Der f 2. Veterinary Dermatology 2017; 28: 183-e40. PMID: 28261915. Olivry T, Dunston SM, Favrot C, Prélaud P and Tsukui T. The novel high molecular weight Dermatophagoides farinae protein Zen-1 is a major allergen in North American and European mite allergic dogs with atopic dermatitis. Veterinary Dermatology 2017; 28: 177-e38. PMID: 28261917. Qurollo BA, Archer NR, Schreeg ME, Marr HS, Birkenheuer AJ, Haney KN, Thomas BS, Breitschwerdt EB. Improved molecular detection of Babesia infections in animals using a novel quantitative real-time PCR diagnostic assay targeting mitochondrial DNA. 2017. Parasites and Vectors 2017; 10: 128

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Bosscher G, Tomas A, Roe S, Marcellin-Little D, Lascelles BDX. Repeatability and accuracy testing of a weight distribution platform and comparison to a pressure sensitive walkway to assess static weight distribution. Vet Comp Orthop Traumatol. 2017 Jan 17. doi: 10.3415/VCOT-16-09-0128. [Epub ahead of print] PMID: 28094423 Royal KD. Medical students rate Black females as less socially connected than other peer groups. J Nat Med Assoc, 2017. Online First. Greene LM, Royal KD, Bradley JM, Lascelles BD, Johnson LR, Hawkins EC. Severity of nasal inflammatory disease questionnaire for canine idiopathic rhinitis control: instrument development and initial validity evidence. J Vet Intern Med 2017; 31:134-141. Royal KD, Flammer K. Survey Incentives in Veterinary Medical Education: What Do Students Say Will Entice Them to Participate in Surveys? Med Sci Educ, 2017. Royal KD, Lybarger M. On Algorithms, ‘Big Data’ and the Future of Psychometrics. Rasch Meas Trans, 2017;30(4):1610-1612. Royal KD. Quality teaching matters more than innovative curricula. Am J Med, 2017. Online First Royal KD, Hedgpeth MW. The Prevalence of Item Construction Flaws in Medical Schools Examinations and Innovative Recommendations for Improvement. Euro Med J, 2017:1(1), 61-66. Schoenfeld-Tacher RM, Horn TJ, Scheviak TA, Royal KD, Hudson LC. Evaluation of 3D additively manufactured canine brain models for teaching veterinary neuroanatomy. J Vet Med Educ, 2017. Online First. Royal KD, Stockdale MR. The impact of 3-option responses to multiple-choice questions on guessing strategies and cutscore determinations. J Adv Med Educ Profess, 2017;5(2):84-89. Bascunan A, Thieman Mankin KM, Saunders AB, Bright JM, Scharf V, Sing A, O’Sullivan L, Brisson B, Estrada AH, Tou SP, RuoffC. Patent ductus arteriosus in cats (Felis catus): 50 cases (2000-2015). J Vet Cardiol 2017;19:35-43.

Lang HM, Schnabel LV, Cassano JM, Fortier LA. Effects of needle diameter on the viability of equine bone marrow derived mesenchymal stem cells. Vet Surg. In press 2017. Sherman AB, Gilger BC, Berglund AK, Schnabel LV. Effect of bone marrow-derived mesenchymal stem cells and stem cell supernatant on equine corneal wound healing in vitro. Stem Cell Research and Therapy. 2017 8:120. Berglund AK, Fisher MB, Cameron KA, Poole EJ, Schnabel LV. TGF-beta2 downregulates MHC I and MHC II surface expression on equine bone marrow-derived mesenchymal stem cells without altering other phenotypic cell surface markers. Frontiers in Veterinary Science. 2017. Niemuth JN, Stoskopf MK. A novel extraction method for the preparation of heparinized chicken (Gallus gallus domesticus) and horse (Equus caballus) whole blood for 1H-NMR metabolomics using Drabkin’s reagent. Journal of Integrated Omics. 2017;7(1):1-6. Phillips BE, Christiansen EF, Stoskopf MK, Broadhurst H, George R, Harms CA. 2016. Comparison of hematology, plasma biochemistry, and blood gas parameters between two venipuncture sites in southern stingrays (Dasyatis americana). Vet Clin Path 45: 627-633. Ullal T, Vaden S, Birkenheuer A. Azotemia and proteinuria in dogs infected with Babesia gibsoni. J Am Anim Hosp Assoc, 2017: Accepted. Gruen ME, Messenger KM, Thomson AE, Griffith EH, Aldrich LA, Vaden S, Lascelles BDX. Evaluation of serum cytokines in cats with and without degenerative joint disease and associated pain. J Vet Immunol Immunopathol, 2017;183:49-59. Vaden S, Williams K, Griffith E, Harris T, Mariani C, Munana K, Early P, Platt S, Boozer L, Giovanella C, Longshore R. (2017) Effect of cranberry extract on the frequency of bacteriuria in dogs with acute thoracolumbar disk herniation: A randomized controlled clinical

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trial. Journal of Veterinary Internal Medicine, 31(1):60-68.

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In the News Turtle Rescue Partnership Turns 20

Dr. Lauren Schnabel Research Connection A Work in Progress: Pioneering Distributive Training in VMC 949 Research in the Spotlight – Dr. Liara Gonzalez

The Wild Carnivore Team The Turtle Team: Vet Students Helping Herps

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Post-doc, Graduate Student & Resident News EMC is excited to announce our three new house officers, who will start their programs in mid-July. DOCS Behavioral Medicine resident, Dr. Kat Pankratz, is the recipient of the American College of Veterinary Behaviorists (ACVB) RK Anderson Research Award for her study on "The safety and efficacy of single dose oral gabapentin to attenuate fear responses in cage-trap confined community cats: a double blind placebo controlled field trial." Dr. Pankratz will be presenting her research at the Veterinary Behavior Symposium this summer. The manuscript has been submitted to the Journal of Feline Medicine and Surgery. Brittany Stevens, an UC Davis intern, presented the following abstract at the 2017 IAAAM meeting in Cancun last week and took second place in the house officer category: Stevens BN, Phillips KL, Lewbart GA, Soto E. 2017. Ultrasonography determination of normal juvenile koi (Cyprinus carpio) anatomy and gender. International Association for Aquatic Animal Medicine, Cancun, Mexico.

2017 AKC Canine Health Foundation Clinician-Scientist Fellows To sustain future advancements in canine and human health, the AKC Canine Health Foundation (CHF) makes it a priority to encourage and support the next generation of canine health researchers. This next generation of researchers is but one piece of the scientific puzzle, building on past discoveries and forging new pathways. Dr. Jeanie Lau, BVSc, is a neurology and neurosurgery resident at North Carolina State College of Veterinary Medicine and an AKC-CHF 2017 Clinician Scientist. Under the mentorship of Dr. Karen Munana, Dr. Lau is researching Steroid Responsive Meningitis-Arteritis (SRMA) in dogs.

Dr. Roe presented Alyx Reinhardt, Lauren Aldrich, Karen Park, Mary Walsh, and Scott Hammer (not present) with the DoCS Clinical Proficiency Award.

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Personal News Dr. Liara Gonzalez had a baby boy, Liev Abel Restrepo-Gonzalez, on April 5th at 6:21PM. He was 4lb 13 ozs and 19 inches long.

Krista Kelsey had a baby boy, Walter, on May 9 at 8:30 pm. He was 9.5 lbs. and 22 inches long.

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Who Am I Dr. Olivia Petritz, Assistant Professor of Avian-Exotic Animal Medicine Dr. Olivia Petritz completed her undergraduate and veterinary degree at Purdue University in Indiana. Following graduation, she completed a small animal medicine and surgery at a specialty hospital in San Diego, CA followed by an exotic animal internship at Gulf Coast Avian and Exotics in Houston, TX. Dr. Petritz returned to California to complete an ACZM residency at the University of California, Davis in companion exotics and zoo medicine, and achieved board certification in November of 2013. She then started an exotics service at a specialty hospital in Los Angeles and worked there for three years prior to coming to NCSU. While not at work, Dr. Petritz enjoys cooking, traveling, and spending time with her family and friends. Dr. Petritz shares her home with her husband, Steven, daughter Eloise (21 months), son Theodore (2 months), Hank (Great Dane), Luke (Rottweiler mix), Sally (DSH), and Beatrice (a guinea pig). Dr. Joanne Intile, Clinical Assistant Professor of Medical Oncology Dr. Joanne Intile grew up on Long Island, NY. She received her DVM from Cornell University and returned home for her internship at Long Island Veterinary Specialists. She completed her residency in medical oncology at Cornell. She then worked in private practice in Rochester, NY, Gaithersburg MD, and Riverhead NY. Dr. Intile and her husband (a veterinary surgeon) share their home with 5 cats. In her free time, she loves running, traveling, and writing. She is a certified veterinary journalist, who focuses on distributing educational material for owners of pets with cancer. Dr. Nimet Browne, Clinical Assistant Professor of Equine Internal Medicine Dr. Nimet Browne is a 2010 graduate of the University of Tennessee, College of Veterinary Medicine. Originally from Nashville, TN, she completed a private practice internship at Kendall Road Equine Hospital in Illinois followed by an internal medicine residency at Virginia Maryland College of Veterinary Medicine. After completing her residency, she pursued a one year fellowship at Hagyard Equine Medicine Institute, then stayed on there as an internist. She is moving here with her rottweiler, Lexi and her favorite activities include running, riding horses, traveling and spending time with friends and family. Dr. Curtis Stiles, Clinical Assistant Professor of Dentistry and Oral Surgery Dr. Curtis Stiles is a 2002 graduate of the Ontario Veterinary College at the University of Guelph, Ontario, Canada. He worked for a short time in private practice in Nova Scotia before starting a small animal medicine and surgery internship at the Atlantic Veterinary College at the University of Prince Edward Island. He subsequently left after 6 months to start his Dentistry and Oral Surgery Residency at the University of Pennsylvania. After completing his residency, he worked in various multi-specialty hospitals: MedVet: Columbus, Ohio 2007-2008, Angell Memorial: Boston, MA 2008-2012 and The LifeCentre: Leesburg, VA (close to DC) 2012-2016. He received his board certification in 2009. Dr. Stiles enjoys cooking/baking, gardening, camping and hiking. He is married to Dr. Mary Lewis, a Clinical Pathologist here at the CVM. Together they are raising 2 boys, Lewis and Reed. Seven and a half and five and a half respectively (they make a big deal about the ½.) Their personal zoo includes 3 mixed breed dogs, a fancy cat, a fuzzy white bunny and an evil goldfish.

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_ _ _ _ _ _ _ _ _ _ Other News and Updates CMAST CMAST Coastal Quarters student and visiting faculty housing is now open and in use! The first occupants were undergraduates in the Semester@CMAST program this spring, and current occupants include CMAST Summer Scholars (undergraduates) and graduate students conducting summer field work. The Second Canine Epilepsy Symposia hosted by the Canine Epilepsy Research Program (Dr. Karen Munana/Julie Nettifee) was held on April 22, 2017. More than 50 pet owners took part in this owner based workshop to support pets with epilepsy and to enhance caregiver support as well. Speakers included Dr. Karen Munana, Dr. Korinn Saker, Jeannine Moga and Julie Nettifee, RVT, BS, VTS. This outreach program was supported by the Archie Fund, through the NCVMF.

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Ashley Busada, Newsletter Editor Next Issue: Summer/Fall 2017