winnie - exercise & drug

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Management of type 2 diabetes mellitus Exercise

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Page 1: Winnie - Exercise & Drug

Management of type 2 diabetes mellitus Exercise

Page 2: Winnie - Exercise & Drug

Aerobic exercise - brisk walking, swimming or dancing about 30 minutes a day, at least 5 days a week

resistance training - weightlifting or yoga twice a week

Page 3: Winnie - Exercise & Drug

BENEFIT OF EXERCISE To prevent macrovascular disease (heart attack, stroke

or diminished blood flow to the legs) weight loss

lower bad cholesterol and triglycerides, and

raise good cholesterol lower blood pressure

lower stress level

reduce the need for insulin

Page 4: Winnie - Exercise & Drug

Body mechanism during exercise With exercise, insulin level in ppl with type 2 DM declines

because insulin acts to store and not release glucose n fat.

You may wonder how insulin can open the cell to the entry of glucose when insulin levels are falling. In fact, two things are at work here. 1. Glucose is getting into muscle cells without the need for

insulin 2. The rapid circulation that comes with exercise is delivering

the smaller amount of insulin more frequently to the muscle → muscle more sensitive to insulin

Page 5: Winnie - Exercise & Drug

DrugOral Injection

Metformin GLP-1 receptor agonists

Sulfonylureas insulinThiazolidinedionesDPP-4 inhibitorsSGLT2 inhibitors

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