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Ulthera, Inc. | 1840 S. Stapley Drive, Suite 200 Mesa, AZ 85204 | tel 1.877.858.4372 | tel 1.480.619.4069 | fax 1.480.619.4071 | www.ultherapy.com Ulthera ® , Inc. is a global, high-growth medical device company pioneering aesthetic and medical applications using its therapeutic ultrasound platform technology. The Ulthera ® System is the first and only energy-based device to receive FDA clearance for a non-invasive aesthetic lift indication. It is used in the face and neck procedure known as Ultherapy ® , which is FDA-approved to lift skin on the neck, under the chin and the brow. Founded in 2004 and based in Mesa, Arizona, Ulthera is a privately held company backed by top-tier venture capital firms New Enterprise Associates and Apposite Capital. One of the best ROIs in the aesthetic industry Bridges the gap between injectables and surgery Compliments other aesthetic treatments you offer Adapt treatment based on patient assessment A platform technology that grows in value every year The ONLY FDA-approved non-invasive procedure that lifts the neck and face A single 60-90 minute procedure with NO downtime Skin color independent; No pre- or post treatment skin care requirements Noticeable results that last 1 year or more WHY CHOOSE ULTHERAPY ® ? HOW CAN SOUND TRANSFORM THE NECK? ...AND THE CHIN? ...AND THE BROW? PATIENT BENEFITS PRACTICE BENEFITS The Ulthera ® System is indicated for use as a non-invasive dermatological aesthetic treatment to lift the eyebrows, submental region (below the chin) and neck. ULTHERAPY HARNESSES THE POWER OF ULTRASOUND FOR THE ONLY FDA-APPROVED NON-INVASIVE LIFT OF THE NECK AND FACE www.ultherapy.com U.S. FDA APPROVED K072505, K121700 ©2013 Ulthera, Inc. Ulthera and Ultherapy are registered trademarks of Ulthera, Inc. 1000066B

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Ulthera, Inc. | 1840 S. Stapley Drive, Suite 200 mesa, AZ 85204 | tel 1.877.858.4372 | tel 1.480.619.4069 | fax 1.480.619.4071 | www.ultherapy.com

Ulthera®, Inc. is a global, high-growth medical device company pioneering aesthetic and medical applications using its therapeutic ultrasound

platform technology. The Ulthera® System is the first and only energy-based device to receive FDA clearance for a non-invasive aesthetic

lift indication. It is used in the face and neck procedure known as Ultherapy®, which is FDA-approved to lift skin on the neck, under the chin

and the brow. Founded in 2004 and based in mesa, Arizona, Ulthera is a privately held company backed by top-tier venture capital firms

New Enterprise Associates and Apposite Capital.

• One of the best ROIs in the aesthetic industry

• bridges the gap between injectables and surgery

• Compliments other aesthetic treatments you offer

• Adapt treatment based on patient assessment

• A platform technology that grows in value every year

• The ONLY FDA-approved non-invasive procedure that

lifts the neck and face

• A single 60-90 minute procedure with NO downtime

• Skin color independent; No pre- or post treatment skin

care requirements

• Noticeable results that last 1 year or more

WHY CHOOSE ULTHERAPY®?

HOw CAN SOUND

TRANSFORm THE NECK?...AND THE CHIN?

...AND THE bROw?

PATIENT BENEFITS PRACTICE BENEFITS

The Ulthera® System is indicated for use as a non-invasive dermatological aesthetic treatment to lift the eyebrows, submental region (below the chin) and neck.

ULTHERAPY HARNESSES THE POWER OF ULTRASOUND

FOR THE ONLY FDA-APPROVED NON-INVASIVE LIFT OF THE NECK AND FACE

www.ultherapy.com

U.S. FDA APPROVEDK072505, K121700

©2013 Ulthera, Inc. Ulthera and Ultherapy are registered trademarks of Ulthera, Inc. 1000066B

ONLY ULTHERA® HAS THESE 3 UNIQUE ADVANTAGES

150,000+ PATIENTS TREATED GLObALLY

1,400+ SYSTEmS SOLD GLObALLY

88+ PATENTS (filed, published or issued)

34+ CLINICAL STUDIES

15+ PUbLISHED PEER-REVIEwED PAPERS

THE ONE & ONLY FDA-APPROVED NON-INVASIVE LIFT

Since launching the Ulthera® System just 4 years ago,

Ulthera has grown into a global leader in non-invasive

aesthetic and medical applications.

Surgical facelifts have evolved to

target deeper tissue planes with

less patient downtime.

Ultherapy is the next evolution in

aesthetic science. It uses micro-

focused ultrasound to non-invasively

treat the same deep tissue planes

as a modern facelift — with NO

patient downtime.

THE SCIENCE OF AESTHETICS HAS EVOLVED TO ULTRASOUND

Epidermis

Dermis

Fat &Connective

Tissue

Muscle

1.0MM

1.5MM

3.0MM

4.5MM

SKIN ONLY SURGICAL FACELIFT

SKIN & MUSCLE SURGICAL FACELIFT

SHORT SCARSURGICAL FACELIFT

1901 1970 1990 2002 2009

MICRO-FOCUSEDULTRASOUND

LASERS RADIO-FREQUENCY

The patented imaging capability of Ulthera

transducers is the only technology that lets you

see where you’re treating — non-invasively.

Like a magnifying glass focusing solar energy,

Ulthera® transducers micro-focus ultrasound energy

below the skin to non-invasively heat tissue.

SURGICAL PRECISION

Collimated Ultrasound For Imaging

Ulthera® DeepSEE® image of the lateral neck and histology of the same tissue.

Micro-Focused Ultrasound For Treatment

SEE TREAT

1.5MMDermis

3.0MMFat/FibrousSeptae

4.5MM

Muscle

• Localized heating at precise depths

• Treats much deeper than lasers and RF

• No affect on the skin’s surface

• Consistently reaches coagulative temperatures (60°– 70°C)

• Denatures collagen & initiates neocollagenesis

• Heats at a precise depth and temperature

• Precise spacing between coagulation points to promote healing

• Repeatable treatment delivery

IN A NON-INVASIVE DEVICE

(Laubach et al, 2008)

1. Depth 2. Temperature 3. Precision

(White et al, 2007) (Gliklich et al, 2007)

ULTHERA®: THE NUmbERS TELL

THE STORY

The growth of Ulthera® is based on

4 UNIQUE AREAS OF EXCELLENCE

1. SCIENCE

1. SCIENCE 2. TECHNOLOGY

3. EFFICACY 4. PRACTICE BENEFITS

2. TECHNOLOGY

3. EFFICACY 3. EFFICACY

RESULTS FROm THE ONLY

FDA-APPROVED NON-INVASIVE LIFT

NON-INVASIVE NECK LIFTPatient Results*

Pre-Treatment Day 180, Single Treatment

bROw

FULL NECK

UPPER FACE

FULL FACE

LOwER FACE

• The ONLY non-invasive procedure that lifts skin on the neck and face

• A single 60-90 minute procedure with NO patient downtime

• Skin color independent; no pre- or post treatment skin care requirements

• Adapt treatment based on patient assessment

• Noticeable results that improve over 90-180 days and last 1 year or more

Pre-Treatment

*Neck Photos Courtesy of Leslie Baumann, M.D.

Day 180, Single Treatment

Pre-Treatment Day 180, Single Treatment

Pre-Treatment Day 90, Single Treatment

Pre-Treatment Pre-Treatment Pre-Treatment

Pre-Treatment

Day 120, Single Treatment Day 180, Single Treatment Day 360, Single Treatment

Day 450, Single Treatment

Pre-Treatment Day 180, Single Treatment

NON-INVASIVE bROwLIFTPatient Results

LOwER FACEPatient Results

" In my opinion, Ultherapy is the best technology to hit dermatology or plastic surgery

since the CO2 laser. I love how natural the results are, and the fact that there’s no

downtime is critical for my practice.” — Kenneth mark m.D., Dermatologist

“Ultherapy has value as a stand-alone modality, but

seems to create synergy with a variety of popular

therapies.” — Julius Few m.D., Plastic Surgeon

“Treating at multiple depths instead of just one, you

would expect better efficacy, and that’s certainly what

I’ve found.” — Richard Asarch m.D., Dermatologist

Pre-Treatment Day 30, Single Treatment

4. PRACTICE BENEFITS 4. PRACTICE BENEFITS

EXPERIENCE THE PRACTICE bENEFITS OF ULTHERAPY®

FACE VS. BODY CONTOURING

$1.8B

$ EXPENDITURES

$4.6B

IMPORTANT STATISTICS*:

920% growth of non-surgical cosmetic procedures

82% of procedures are non-surgical

71% of expenditures are on the face

7x more face vs. body patients (35–50)

16:1 ratio of face to body patients age 51+

WHY CHOOSE ULTHERAPY?

• One of the best ROIs in the aesthetic industry

• Bridges the gap between injectables and surgery

• Adapt treatment based on patient assessment

• Platform technology that grows in value each year

ULTHERA PARTNERS wITH YOU FOR YOUR SUCCESS

PATIENT AwARENESS IS GROwING EXPONENTIALLY

At Ulthera®, we partner with you to optimize clinical efficacy

and grow treatment volume.

• On-site clinical training, with advanced training options

• Dedicated team of practice marketing experts

• Inclusion on the Ultherapy.com physician locator

• 24/7 access to the Online marketing & Resource Portal

• Dozens of print, digital and social media assets

millions of patients around the world are learning about Ultherapy

as media coverage continues to grows exponentially every year.

TELEVISION

The Doctors; Rachael Ray;

20/20; E! News; The View;

Entertainment Tonight;

Good Morning America;

The TODAY Show; Extra!;

Bravo TV; The Martha

Stewart Show; CBS Early

Show; Fox News Health;

America Now; and more...

PRINT MEDIA

Vogue; Harper’s Bazaar;

Elle; Health; Marie Claire;

O, The Oprah Magazine;

Good Housekeeping;

MORE; Allure; New Beauty;

Self; Details; Instinct;

Men’s Journal; In Style;

The Wall Street Journal;

Cosmopolitan; and more...

DIGITAL MEDIA

RealSelf.com; Glam.com;

NYTimes.com; WSJ.com;

ABCnews.com; Martha

Stewart.com; Examiner.

com; Self.com; Vogue.

com; USAToday.com;

Allure.com; More.com;

SheKnows.com; Total-

Beauty.com; and more...

DO NOT TREAT THIS

AREA

DO NOT TREAT THIS

AREA

Pa

tien

t Tr

ea

tme

nt

Re

co

rd

Patient Name Date

1001284A

NO

TES

- Avoid treating directly over bone, as it may increase discomfort.

- Always treat with the deepest transducer first (DS 4-4.5), then move superficially towards the skin’s surface (DS 7-3.0).

- Refer to the Ulthera System Information For Use (IFU) and Treatment Reference Guide for additional treatment information.

- Do not treat over the thyroid gland, thyroid cartilage or trachea.

- Do not treat posterior to the preauricular line / tragus.

- Avoid treating major vessels. Vessels appear as round, dark structures on the DeepSee™ ultrasound image.

3.0 mm

4.5 mm

NECK

10-1

.57-3

.07-4

.5

1

2

3

23

10-1

.57-3

.0

10-1

.57-3

.0

1

DO NOT TREAT THIS

AREA

PATIENT PREPARATION Prior to the start of the treatment, have the patient remove all make- up with water, skin cleanser, and gauze. Gently dry the area to be treated and have the patient lie down on the treatment table.

PATIENT MARKING Draw a vertical line in front of the ear. Do not treat behind this line.

Upper Neck

Draw a line marking the border of the jaw bone (mandible).

Palpate the thyroid cartilage. Draw a horizontal line from the top of the cartilage to the bottom of each ear.*

Place the card over the submental area and mark the outside of the card. Measure 1-3 card widths to either side, drawing a line each time you move the card*. DO NOT pass the line in front of the ear.

Lower Neck

Place a card at the right edge of the cricoid cartilage (outside the trachea). Draw a line down both sides of the card from the cartilage to the collar bone (clavicle), being careful to avoid the thyroid.

*. Add columns as needed, but DO NOT pass the line in front of the ear.

Repeat Step 1 - 2 on the left side.

1

1

A

2

2

3

3

DO NOT TREAT THIS

AREA

DO NOT TREAT THIS

AREA

A

Preauricular Line

*When moving the marking card, overlap each column by 1-2 dots to ensure proper density

Non-Invasive Lifting & Tightening of the Neck, Chin and Brow

See What Sound Can Do For You. Schedule a Consultation Today! 1001691A

Gina, 46“The loose skin at my neck tightened immediately.”

Coleen, 45“It completely lifted my forehead!”

Diana, 62“I have more

the chin!”

Before After 90 Days

Before After 450 Days

Before After 90 Days

Before After 360 Days

Before After 120 Days

SEE THE SOUND RESULTS

The only non-invasive procedure

FDA-approved to lift the

Neck, Chin and Brow

• NO DOWNTIME

• NATURAL RESULTS

• NO TOXINS OR FILLERS

• IT’S ULTRASOUND!

• SEE A HIGHER BROW

• SEE A TIGHTER NECK

• SEE A LIFT UNDER THE CHIN

ALL WITH A SINGLE NON-INVASIVE TREATMENT

SEE THE BEAUTIFUL BENEFITS OF SOUND

Corporate Headquarters1840 S. Stapley Drive, Suite 200, Mesa, AZ 85204

1-877-ULTHERA1-877-858-4372

The Ulthera® System is indicated for use as a non-invasive dermatological aesthetic treatment to lift the eyebrow and lift lax submental (beneath the chin) and neck tissue. ©2013 Ulthera, Inc. Ulthera and Ultherapy are registered trademarks of Ulthera, Inc. 1001689A.

Learn more at

Ultherapy.com

Patient Name

Date

1001505A

Patient Record:

FACE

4.5MM DEPTH

3.0MM DEPTH

Do Not Treat This AreaGeneral location of key facial nervesSupraorbital, Temporal Facial and Marginal Mandibular Nerves

or

N

What can sound do for your skin?

What can sound do for your skin?

1001880A

1001880A

You’re Invited to

A Neck Affair

You’re Invited to

A Neck Affair

1001884A

1001884A

FACE bODY CONTOURING

ULTHERAPY MEDIA IMPRESSIONS

TV ImpressionsPrint & Online Impressions

40m

80m

120m

160m

2010 2011 2012

“Ihavepatientswhoaren’treadyforafacelift,butwantanon-invasive

waytogetridoffaciallaxity.IfIdidn’townthisdevice,Iwouldn’thave

anythingtoofferthem.”— william Vasileff m.D., Plastic Surgeon

"Ultherapyhasbecomemysignatureprocedure.Itbridgesthegapbetween

dermalfillersandfacelifts.”—Kelly O’malley-mattone m.D., Cosmetic Physician

"Ultherapyhasbeenagatewaytreatmentformypractice.Itquadrupled

newpatienttraffic,givingpatientsanopportunitytoseethespectrum

ofmyexpertise.”— matthew white m.D., Facial Plastic Surgeon

*Source: The American Society for Aesthetic Plastic Surgery Cosmetic Surgery National Data Bank Statistics 2011; Zeltiq® 2011 Annual ReportData set comprised of elective aesthetic surgical and non-surgical procedures for body contouring / fat reduction and facial procedures including face lifts, injectables and skin rejuvenation

THE SOUND CHOICEFOR AN AESTHETIC PRACTICE

COSMETIC PROCEDURE GROWTH

625K

1m–

19-34

35-50

51-64

65+

2m

PATIENTS BY AGE

2m

4m

6m

8m

1997 2011

10m

SURGICAL NON-SURGICAL

CLINICAL & MARKETING TOOLS