whose vis is it anyway? the human microbiome, health & the vis medicatrix naturae paul mittman,...

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Whose Vis is it Anyway? The Human Microbiome, Health & the Vis Medicatrix Naturae Paul Mittman, ND, EdD

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Page 1: Whose Vis is it Anyway? The Human Microbiome, Health & the Vis Medicatrix Naturae Paul Mittman, ND, EdD

Whose Vis is it Anyway?The Human Microbiome, Health

& the Vis Medicatrix NaturaePaul Mittman, ND, EdD

Page 2: Whose Vis is it Anyway? The Human Microbiome, Health & the Vis Medicatrix Naturae Paul Mittman, ND, EdD
Page 3: Whose Vis is it Anyway? The Human Microbiome, Health & the Vis Medicatrix Naturae Paul Mittman, ND, EdD

Human Microbiome

The microbiome is defined as the collective genomes of the microbes (composed of bacteria, bacteriophage, fungi, protozoa and viruses) that live inside and on the human body.

National Human Genome Research Institute

http://www.genome.gov/27549400

Page 4: Whose Vis is it Anyway? The Human Microbiome, Health & the Vis Medicatrix Naturae Paul Mittman, ND, EdD

Human History of Disease Shaped our Relationship with Microbes

Page 5: Whose Vis is it Anyway? The Human Microbiome, Health & the Vis Medicatrix Naturae Paul Mittman, ND, EdD

Causes of Death 1900/2010

NEJM

Page 6: Whose Vis is it Anyway? The Human Microbiome, Health & the Vis Medicatrix Naturae Paul Mittman, ND, EdD

Medicine as Opposition to Disease

Page 7: Whose Vis is it Anyway? The Human Microbiome, Health & the Vis Medicatrix Naturae Paul Mittman, ND, EdD

Symbiosis in Biological Systems

Page 8: Whose Vis is it Anyway? The Human Microbiome, Health & the Vis Medicatrix Naturae Paul Mittman, ND, EdD

Legumes

Page 9: Whose Vis is it Anyway? The Human Microbiome, Health & the Vis Medicatrix Naturae Paul Mittman, ND, EdD

Hermann Hellriegel 1888

Nitrogen Fixation in Leguminous Plants

Page 10: Whose Vis is it Anyway? The Human Microbiome, Health & the Vis Medicatrix Naturae Paul Mittman, ND, EdD

Symbiosis

• Mutualism – Both Organisms Benefit

• Commensalism – One Benefits the other unaffected

• Parasitism – One Benefits, the other harmed

Page 11: Whose Vis is it Anyway? The Human Microbiome, Health & the Vis Medicatrix Naturae Paul Mittman, ND, EdD

© 2010 Shigeharu Moriya

http://www.riken.jp/en/research/rikenresearch/highlights/6214

Termites, Bacteria and Protists

Page 12: Whose Vis is it Anyway? The Human Microbiome, Health & the Vis Medicatrix Naturae Paul Mittman, ND, EdD

Termites, Bacteria and Protists

Page 13: Whose Vis is it Anyway? The Human Microbiome, Health & the Vis Medicatrix Naturae Paul Mittman, ND, EdD

Hawaiian Bobtail Squid

Euprymna scolopes /Vibrio fischeri

The Bacterium and the Squid

Page 14: Whose Vis is it Anyway? The Human Microbiome, Health & the Vis Medicatrix Naturae Paul Mittman, ND, EdD
Page 15: Whose Vis is it Anyway? The Human Microbiome, Health & the Vis Medicatrix Naturae Paul Mittman, ND, EdD

Mutualism

Page 16: Whose Vis is it Anyway? The Human Microbiome, Health & the Vis Medicatrix Naturae Paul Mittman, ND, EdD

Symbiosis in Human Health

Page 17: Whose Vis is it Anyway? The Human Microbiome, Health & the Vis Medicatrix Naturae Paul Mittman, ND, EdD

Plasmodium Falciparum

Page 18: Whose Vis is it Anyway? The Human Microbiome, Health & the Vis Medicatrix Naturae Paul Mittman, ND, EdD

Helicobacter pylori

Page 19: Whose Vis is it Anyway? The Human Microbiome, Health & the Vis Medicatrix Naturae Paul Mittman, ND, EdD

Human Microbiome

Page 20: Whose Vis is it Anyway? The Human Microbiome, Health & the Vis Medicatrix Naturae Paul Mittman, ND, EdD

Illya Ilyich (Elie) MetchnikoffNobel Prize 1908

Page 21: Whose Vis is it Anyway? The Human Microbiome, Health & the Vis Medicatrix Naturae Paul Mittman, ND, EdD

Proposed Lactobacillus Consumption

Page 22: Whose Vis is it Anyway? The Human Microbiome, Health & the Vis Medicatrix Naturae Paul Mittman, ND, EdD

Polymerase Chain Reaction

Individual CulturePCR

Page 23: Whose Vis is it Anyway? The Human Microbiome, Health & the Vis Medicatrix Naturae Paul Mittman, ND, EdD

Human Microbiome

Page 24: Whose Vis is it Anyway? The Human Microbiome, Health & the Vis Medicatrix Naturae Paul Mittman, ND, EdD
Page 25: Whose Vis is it Anyway? The Human Microbiome, Health & the Vis Medicatrix Naturae Paul Mittman, ND, EdD

Microbial contact during pregnancy, intestinal colonization and human disease

Nature Reviews Gastroenterology and Hepatology 9, 565-576 (October 2012) | doi:10.1038/nrgastro.2012.144

In Utero

At Birth

Perinatal Antibiotics

Breastfeeding

Microbial Transmission

Page 26: Whose Vis is it Anyway? The Human Microbiome, Health & the Vis Medicatrix Naturae Paul Mittman, ND, EdD

Microbial Transmission via Breastmilk

The human milk microbiota: origin and potential roles in health and disease.Pharmacol Res. 2013 Mar;69(1):1-10

Page 27: Whose Vis is it Anyway? The Human Microbiome, Health & the Vis Medicatrix Naturae Paul Mittman, ND, EdD
Page 28: Whose Vis is it Anyway? The Human Microbiome, Health & the Vis Medicatrix Naturae Paul Mittman, ND, EdD

Human Milk Oligosaccharides

Bifidobacterium longum subspecies infantis

Page 29: Whose Vis is it Anyway? The Human Microbiome, Health & the Vis Medicatrix Naturae Paul Mittman, ND, EdD

TMAO & Heart Dz

Page 30: Whose Vis is it Anyway? The Human Microbiome, Health & the Vis Medicatrix Naturae Paul Mittman, ND, EdD

Genomic Phylostratigraphy

Page 31: Whose Vis is it Anyway? The Human Microbiome, Health & the Vis Medicatrix Naturae Paul Mittman, ND, EdD

Genomic Phylostratigraphy

Page 32: Whose Vis is it Anyway? The Human Microbiome, Health & the Vis Medicatrix Naturae Paul Mittman, ND, EdD

Questions

Whose vis is it? Does an individual’s microbiome play a role in energetic therapies?Can the microbiome help explain naturopathic medicine’s vitalistic approach to healthcare?