what is the state of the evidence for omega-3s in cardiovascular health? omega-3 centre scientific...
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What is the state of the evidence What is the state of the evidence for omega-3s in Cardiovascular for omega-3s in Cardiovascular
Health?Health?
Omega-3 Centre Scientific Consensus Meeting 2010Omega-3 Centre Scientific Consensus Meeting 2010
Crowne Plaza Canberra Crowne Plaza Canberra
Omega-3 Centre Scientific Consensus Meeting 2010Omega-3 Centre Scientific Consensus Meeting 2010
Crowne Plaza Canberra Crowne Plaza Canberra
Assoc Prof David Colquhoun 11th November 2010Assoc Prof David Colquhoun 11th November 2010
University of Queensland, Wesley Hospital, Brisbane, Australia www.coreresearchgroup.com
Slides prepared by David Colquhoun & Jennefer Shields
University of Queensland, Wesley Hospital, Brisbane, Australia www.coreresearchgroup.com
Slides prepared by David Colquhoun & Jennefer Shields
Disclosures specific to EPA/DHADisclosures specific to EPA/DHA
I take 1800-2400 EPA&DHA in ethyl ester form dailyI take 1800-2400 EPA&DHA in ethyl ester form daily
I eat 200-600 gm fish per weekI eat 200-600 gm fish per week
I am the Chief Author of the National Heart Foundation I am the Chief Author of the National Heart Foundation Australia Position Statement on Fish, Fish oils, n-3 PUFA and Australia Position Statement on Fish, Fish oils, n-3 PUFA and CV Health CV Health www.heartfoundation.org.au
I presented a poster on the 2010 Update on NHFA marine n-3 I presented a poster on the 2010 Update on NHFA marine n-3 fatty acid at the CSANZ Meeting fatty acid at the CSANZ Meeting
Source of “fish oil” and ethyl Source of “fish oil” and ethyl EPA/DHAEPA/DHA
(A crustacean)(A crustacean)
““The Beginning”The Beginning” Krill eat planktonKrill eat plankton Fish eat Fish eat KrillKrill
PhytoplanktonPhytoplankton
Fish eat fishFish eat fish
CapsuleCapsuleEicosapentaenoic acid (C20:5n-3 [EPA] & Eicosapentaenoic acid (C20:5n-3 [EPA] &
Docosahexaenoic acid (C22:6n-3 [DHA])Docosahexaenoic acid (C22:6n-3 [DHA])
Almost NO fish (like humans) can make EPA/DHA Almost NO fish (like humans) can make EPA/DHA (exception – the Queensland Barramundi Cod)(exception – the Queensland Barramundi Cod)
Fish, Fish Oil and Long Chain Omega-Fish, Fish Oil and Long Chain Omega-3 Fatty Acids 3 Fatty Acids
NHFA Position NHFA Position StatementStatement
PRIMARY WRITERSPRIMARY WRITERS A/Prof D Colquhoun, Mr A Ferreira-JardimA/Prof D Colquhoun, Mr A Ferreira-Jardim
NHFA NUTRITION & METABOLISM COMMITTEENHFA NUTRITION & METABOLISM COMMITTEE Dr M Noakes (Chair), Prof P Barter, Prof M Ball, A/Prof D Colquhoun, Prof Dr M Noakes (Chair), Prof P Barter, Prof M Ball, A/Prof D Colquhoun, Prof D Crawford, A/Prof L Kritharides, Ms M Miller, A/Prof R O’Brien, A/Prof D Crawford, A/Prof L Kritharides, Ms M Miller, A/Prof R O’Brien, A/Prof L Simons, A/Prof D Sullivan, Dr D Topping. L Simons, A/Prof D Sullivan, Dr D Topping. NHFA Staff:NHFA Staff: Dr P Abernethy. Ms S Anderson, Ms C Cooper, Dr P Abernethy. Ms S Anderson, Ms C Cooper, Ms E Thompson, Ms B Eden, Ms E Thompson, Ms B Eden,
INTERNAL NHFA REVIEWINTERNAL NHFA REVIEW National Cardiovascular Health Advisory Committee National Cardiovascular Health Advisory Committee National Board of NHFANational Board of NHFA
EXTERNAL REVIEWERSEXTERNAL REVIEWERS A/Prof P Clifton, A/Prof R Gibson, Prof P Howe, Dr M James, A/Prof P Clifton, A/Prof R Gibson, Prof P Howe, Dr M James, A/Prof A Keech, A/Prof K Kostner, A/Prof T Mori, Prof P Nestel, A/Prof A Keech, A/Prof K Kostner, A/Prof T Mori, Prof P Nestel, Prof A Sinclair, Dr S Somerset, Prof AS Truswell, Prof A Sinclair, Dr S Somerset, Prof AS Truswell, Prof K O’DeaProf K O’Dea
NHFA Health Professional advice NHFA Health Professional advice 20082008
www.heartfoundation.org.auwww.heartfoundation.org.au
Definition of Oily FishDefinition of Oily FishNHFA Position StatementNHFA Position Statement
LeanLean < < 1% Fat (body weight)1% Fat (body weight)
e.g. Cod, troute.g. Cod, trout
IntermediateIntermediate 1 - 10% Fat1 - 10% Fat
e.g. Trout, sea bass, breame.g. Trout, sea bass, bream
OilyOily >> 10% Fat10% Fat
e.g. Atlantic salmon, herring, swordfishe.g. Atlantic salmon, herring, swordfish