what is the difference between mitosis and meiosis? when will each occur?

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What is the difference between mitosis and meiosis? When will each occur?

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Page 2: What is the difference between mitosis and meiosis? When will each occur?

The cell cycleObjectives Outcomes

3: Identify stages of the cell cycle.

5: Describe the stages of the cell cycle.

7: Explain the consequences of the cell cycle not being properly

controlled.

Key terms: cell cycle, interphase, mitosis, cytokinesis.

Page 3: What is the difference between mitosis and meiosis? When will each occur?

The Cell Cycle, Mitosis, and Meiosis

New cells can only be made when existing cells divide. All cells have the ability to divide – but some cells lose this ability.

Intestinal epithelial lining - replaced every five days by cell divisionLiver cells - divide only to repair damage, and then stop dividingBone marrow cells - divide repeatedly to produce red and white blood cellsMeristem cells (tips of roots and shoots) – divide to produce new growthCambium cells (plants) – divide to form vascular tissue (xylem and phloem)

These are relatively unspecialised cells. Specialised cells often go through the cell cycle only once - the nerve cells, once formed cannot divide again.

In eukaryotic cells, there are two types of cell division – mitosis and meiosis. Mitosis is used to produce new cells for growth and repair. Meiosis is used in the formation of gametes only.

In prokaryotes (bacteria), cell division does not involve mitosis or meiosis – bacteria reproduce asexually, by a type of cell division termed by binary fission. Yeasts reproduce asexually by budding.

The cell cycle is the process that all body cells from multicellular organisms use to grow and divide. The cell cycle starts when a cell has been produced by cell division and ends with the cell dividing to produce two identical cells.

Page 4: What is the difference between mitosis and meiosis? When will each occur?

The cell cycleThe cell cycle describes the sequence of cell growth and cell division.

It includes:Interphase

cell growth synthesis of organelles DNA copying and checking of genetic information

Mitosischromosomes divide

Cytokinesiscytoplasm divided between the daughter cells

Key terms: cell cycle, interphase, mitosis, cytokinesis.

Page 5: What is the difference between mitosis and meiosis? When will each occur?

The cell cycleThe cell cycle describes the events during one complete cycle of division, they are represented in the chart:

Key terms: cell cycle, interphase, mitosis, cytokinesis.

Page 6: What is the difference between mitosis and meiosis? When will each occur?

The cell cycle

Key terms: cell cycle, interphase, mitosis, cytokinesis.

Page 7: What is the difference between mitosis and meiosis? When will each occur?

MITOSIS (M)

Process by which a nucleus divides into two – each with an identical set of chromosomes – the nuclei are genetically identical

Four phases – prophase, metaphase, anaphase, and telophase

Followed by cytokinesis – division of the cell into two genetically identical daughter cells

INTERPHASE

Period of cell growth; cell prepares cell for cell division (mitosis); genetic material (DNA) is copied and checked for errors – prevents mutations being passed on

No apparent activity

New organelles and proteins are made

Divided into three phases (G1, S, and G2 phase)CELL

CYCLE

G1

S phase

G2

Mitosis (M)

Two daughter cells – genetically identical

Page 8: What is the difference between mitosis and meiosis? When will each occur?

The cell cycle can be divided into stages:

G1 (“growth phase” 1) - Cells prepare for DNA replicationS (“synthesis”) - DNA replication occursG2 (“growth phase” 2)- Short gap before mitosisM Mitosis (relatively short)

Affected by availability of nutrients

Between each stage the cell “checks” to see if it is OK to proceed to the next stage.

“Proof-reading” enzymes check the copied chromosomes for mistakes (mutations) – the cell may kill itself (undergo “suicide”) if harmful mutations are – a process known as apoptosis.

Bacterial cells complete the cycle every 20 minutes. Muscle cells never complete the cycle – “terminal differentiation”

Uncontrolled and repeated cell division by mitosis results in cancer (tumours)

Eukaryotic cells have a well- defined cell cycle of growth and division (mitosis). The length of the cycle varies (from minutes to hours, or , longer) ending with mitosis.

Each phase of the cycle involves specific activities, and varies in length from one organism to another.

The Cell Cycle

Page 9: What is the difference between mitosis and meiosis? When will each occur?

G1 + S + G2 = INTERPHASE No apparent observable activity

Cytokinesis – cell divides into twoDNA content = normal

G1 - First growth phase – longest phaseProtein synthesis – cell “grows”Most organelles producedVolume of cytoplasm increasesCell differentiation (switching on or off of genes)Length depends on internal and external factorsIf cell is not going to divide again it remains in this phaseDNA content = 20 (arbitary)

S - Replication phase DNA replication – this must occur if mitosis is to take placeThe cell enters this phase only if cell division is to followDNA content = double

G2 - Second growth phase - shortShort gap before mitosis (cell division)Cytoskeleton of cell breaks down and the protein microtubule components begin to reassemble into spindle fibres – required for cell divisionDNA content = 40

The Cell Cycle

Page 10: What is the difference between mitosis and meiosis? When will each occur?

The cell cycleTask

Create a poster outlining the cell cycle. Leave some space

for when we fully look at mitosis in the next lesson.

Outcomes

3: Identify stages of the cell cycle.

5: Describe the stages of the cell cycle.

7: Explain the consequences of the cell cycle not being properly

controlled.

Key terms: cell cycle, interphase, mitosis, cytokinesis.

Page 11: What is the difference between mitosis and meiosis? When will each occur?

The cell cycleWhat happens when the cell

cycle is not controlled:

Cancer

Outcomes

3: Identify stages of the cell cycle.

5: Describe the stages of the cell cycle.

7: Explain the consequences of the cell cycle not being properly

controlled.

Key terms: cell cycle, interphase, mitosis, cytokinesis.

Page 12: What is the difference between mitosis and meiosis? When will each occur?

The cell cycle

Key terms: cell cycle, interphase, mitosis, cytokinesis.