what is restasis - aao.org
TRANSCRIPT
![Page 1: What is Restasis - aao.org](https://reader033.vdocuments.us/reader033/viewer/2022061306/629d8aa9b733c83875598a2c/html5/thumbnails/1.jpg)
Q
What is Restasis?
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Restasis
![Page 2: What is Restasis - aao.org](https://reader033.vdocuments.us/reader033/viewer/2022061306/629d8aa9b733c83875598a2c/html5/thumbnails/2.jpg)
A
What is Restasis? Topical cyclosporine
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Restasis
![Page 3: What is Restasis - aao.org](https://reader033.vdocuments.us/reader033/viewer/2022061306/629d8aa9b733c83875598a2c/html5/thumbnails/3.jpg)
Q
What is Restasis? Topical cyclosporine Broadly speaking, what sort of drug is it?
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Restasis
![Page 4: What is Restasis - aao.org](https://reader033.vdocuments.us/reader033/viewer/2022061306/629d8aa9b733c83875598a2c/html5/thumbnails/4.jpg)
A4
What is Restasis? Topical cyclosporine Broadly speaking, what sort of drug is it? What
effect does it have? An immunomodulatory drug
Restasis
![Page 5: What is Restasis - aao.org](https://reader033.vdocuments.us/reader033/viewer/2022061306/629d8aa9b733c83875598a2c/html5/thumbnails/5.jpg)
Q
What is Restasis? Topical cyclosporine Broadly speaking, what sort of drug is it? What
effect does it have? An immunomodulatory drug
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Restasis
![Page 6: What is Restasis - aao.org](https://reader033.vdocuments.us/reader033/viewer/2022061306/629d8aa9b733c83875598a2c/html5/thumbnails/6.jpg)
A
What is Restasis? Topical cyclosporine Broadly speaking, what sort of drug is it? What
effect does it have? An immunomodulatory drug. It downregulates T-cell-mediated inflammation.
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Restasis
![Page 7: What is Restasis - aao.org](https://reader033.vdocuments.us/reader033/viewer/2022061306/629d8aa9b733c83875598a2c/html5/thumbnails/7.jpg)
Q
What is Restasis? Topical cyclosporine Broadly speaking, what sort of drug is it? What
effect does it have? An immunomodulatory drug. It downregulates T-cell-mediated inflammation.
How long does it take to work?
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Restasis
![Page 8: What is Restasis - aao.org](https://reader033.vdocuments.us/reader033/viewer/2022061306/629d8aa9b733c83875598a2c/html5/thumbnails/8.jpg)
A
What is Restasis? Topical cyclosporine Broadly speaking, what sort of drug is it? What
effect does it have? An immunomodulatory drug. It downregulates T-cell-mediated inflammation.
How long does it take to work? At least 3 months (often 6 months for full effect)
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Restasis
![Page 9: What is Restasis - aao.org](https://reader033.vdocuments.us/reader033/viewer/2022061306/629d8aa9b733c83875598a2c/html5/thumbnails/9.jpg)
Q
What is Restasis? Topical cyclosporine Broadly speaking, what sort of drug is it? What
effect does it have? An immunomodulatory drug. It downregulates T-cell-mediated inflammation.
How long does it take to work? At least 3 months (often 6 months for full effect)
Why so long?
9
Restasis
![Page 10: What is Restasis - aao.org](https://reader033.vdocuments.us/reader033/viewer/2022061306/629d8aa9b733c83875598a2c/html5/thumbnails/10.jpg)
A
What is Restasis? Topical cyclosporine Broadly speaking, what sort of drug is it? What
effect does it have? An immunomodulatory drug. It downregulates T-cell-mediated inflammation.
How long does it take to work? At least 3 months (often 6 months for full effect)
Why so long? Probably related to the length of the T-cell life cycle (about 120 days)
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Restasis
![Page 11: What is Restasis - aao.org](https://reader033.vdocuments.us/reader033/viewer/2022061306/629d8aa9b733c83875598a2c/html5/thumbnails/11.jpg)
Q
Prednisoloneacetate 1% Restasis
Cataractogenic? Yes No
Inhibits epithelial healing? Yes No
Glaucomagenic? Yes No
Potentiates HSV infection? Yes No
Increases risk of fungal
keratopathy?Yes No
Restasis vs Steroids: The good news…
11
Restasis
![Page 12: What is Restasis - aao.org](https://reader033.vdocuments.us/reader033/viewer/2022061306/629d8aa9b733c83875598a2c/html5/thumbnails/12.jpg)
A
Prednisoloneacetate 1% Restasis
Cataractogenic? Yes No
Inhibits epithelial healing? Yes No
Glaucomagenic? Yes No
Potentiates HSV infection? Yes No
Increases risk of fungal
keratopathy?Yes No
Restasis vs Steroids: The good news…
12
Restasis
![Page 13: What is Restasis - aao.org](https://reader033.vdocuments.us/reader033/viewer/2022061306/629d8aa9b733c83875598a2c/html5/thumbnails/13.jpg)
Q
Prednisoloneacetate 1% Restasis
Cataractogenic? Yes No
Inhibits epithelial healing? Yes No
Glaucomagenic? Yes No
Potentiates HSV infection? Yes No
Increases risk of fungal
keratopathy?Yes No
Restasis vs Steroids: The good news…
13
Restasis
![Page 14: What is Restasis - aao.org](https://reader033.vdocuments.us/reader033/viewer/2022061306/629d8aa9b733c83875598a2c/html5/thumbnails/14.jpg)
A
Prednisoloneacetate 1% Restasis
Cataractogenic? Yes No
Inhibits epithelial healing? Yes No
Glaucomagenic? Yes No
Potentiates HSV infection? Yes No
Increases risk of fungal
keratopathy?Yes No
Restasis vs Steroids: The good news…
14
Restasis
![Page 15: What is Restasis - aao.org](https://reader033.vdocuments.us/reader033/viewer/2022061306/629d8aa9b733c83875598a2c/html5/thumbnails/15.jpg)
Q
Prednisoloneacetate 1% Restasis
Cataractogenic? Yes No
Inhibits epithelial healing? Yes No
Glaucomagenic? Yes No
Potentiates HSV infection? Yes No
Increases risk of fungal
keratopathy?Yes No
Restasis vs Steroids: The good news…
15
Restasis
![Page 16: What is Restasis - aao.org](https://reader033.vdocuments.us/reader033/viewer/2022061306/629d8aa9b733c83875598a2c/html5/thumbnails/16.jpg)
A
Prednisoloneacetate 1% Restasis
Cataractogenic? Yes No
Inhibits epithelial healing? Yes No
Glaucomagenic? Yes No
Potentiates HSV infection? Yes No
Increases risk of fungal
keratopathy?Yes No
Restasis vs Steroids: The good news…
16
Restasis
![Page 17: What is Restasis - aao.org](https://reader033.vdocuments.us/reader033/viewer/2022061306/629d8aa9b733c83875598a2c/html5/thumbnails/17.jpg)
Q
Prednisoloneacetate 1% Restasis
Cataractogenic? Yes No
Inhibits epithelial healing? Yes No
Glaucomagenic? Yes No
Potentiates HSV infection? Yes No
Increases risk of fungal
keratopathy?Yes No
Restasis vs Steroids: The good news…
17
Restasis
![Page 18: What is Restasis - aao.org](https://reader033.vdocuments.us/reader033/viewer/2022061306/629d8aa9b733c83875598a2c/html5/thumbnails/18.jpg)
A
Prednisoloneacetate 1% Restasis
Cataractogenic? Yes No
Inhibits epithelial healing? Yes No
Glaucomagenic? Yes No
Potentiates HSV infection? Yes No
Increases risk of fungal
keratopathy?Yes No
Restasis vs Steroids: The good news…
18
Restasis
![Page 19: What is Restasis - aao.org](https://reader033.vdocuments.us/reader033/viewer/2022061306/629d8aa9b733c83875598a2c/html5/thumbnails/19.jpg)
Q
Prednisoloneacetate 1% Restasis
Cataractogenic? Yes No
Inhibits epithelial healing? Yes No
Glaucomagenic? Yes No
Potentiates HSV infection? Yes No
Increases risk of fungal
keratopathy?Yes No
Restasis vs Steroids: The good news…
19
Restasis
![Page 20: What is Restasis - aao.org](https://reader033.vdocuments.us/reader033/viewer/2022061306/629d8aa9b733c83875598a2c/html5/thumbnails/20.jpg)
A
Prednisoloneacetate 1% Restasis
Cataractogenic? Yes No
Inhibits epithelial healing? Yes No
Glaucomagenic? Yes No
Potentiates HSV infection? Yes No
Increases risk of fungal
keratopathy?Yes No
Restasis vs Steroids: The good news…
20
Restasis
![Page 21: What is Restasis - aao.org](https://reader033.vdocuments.us/reader033/viewer/2022061306/629d8aa9b733c83875598a2c/html5/thumbnails/21.jpg)
Q
Prednisoloneacetate 1% Restasis
Cataractogenic? Yes No
Inhibits epithelial healing? Yes No
Glaucomagenic? Yes No
Potentiates HSV infection? Yes No
Increases risk of fungal
keratopathy?Yes No
Prednisolone acetate 1% Restasis
Expensive? No Yes
Slow to work? No Yes
Stings/burns? No Yes
Reduces risk of PK rejection? Yes No
Generic available? Yes No
…and the badRestasis vs Steroids: The good news…
21
Restasis
![Page 22: What is Restasis - aao.org](https://reader033.vdocuments.us/reader033/viewer/2022061306/629d8aa9b733c83875598a2c/html5/thumbnails/22.jpg)
A
Prednisoloneacetate 1% Restasis
Cataractogenic? Yes No
Inhibits epithelial healing? Yes No
Glaucomagenic? Yes No
Potentiates HSV infection? Yes No
Increases risk of fungal
keratopathy?Yes No
Prednisolone acetate 1% Restasis
Expensive? No Yes
Slow to work? No Yes
Stings/burns? No Yes
Reduces risk of PK rejection? Yes No
Generic available? Yes No
…and the badRestasis vs Steroids: The good news…
22
Restasis
![Page 23: What is Restasis - aao.org](https://reader033.vdocuments.us/reader033/viewer/2022061306/629d8aa9b733c83875598a2c/html5/thumbnails/23.jpg)
Q
Prednisoloneacetate 1% Restasis
Cataractogenic? Yes No
Inhibits epithelial healing? Yes No
Glaucomagenic? Yes No
Potentiates HSV infection? Yes No
Increases risk of fungal
keratopathy?Yes No
Prednisolone acetate 1% Restasis
Expensive? No Yes
Slow to work? No Yes
Stings/burns? No Yes
Reduces risk of PK rejection? Yes No
Generic available? Yes No
…and the badRestasis vs Steroids: The good news…
23
Restasis
![Page 24: What is Restasis - aao.org](https://reader033.vdocuments.us/reader033/viewer/2022061306/629d8aa9b733c83875598a2c/html5/thumbnails/24.jpg)
A
Prednisoloneacetate 1% Restasis
Cataractogenic? Yes No
Inhibits epithelial healing? Yes No
Glaucomagenic? Yes No
Potentiates HSV infection? Yes No
Increases risk of fungal
keratopathy?Yes No
Prednisolone acetate 1% Restasis
Expensive? No Yes
Slow to work? No Yes
Stings/burns? No Yes
Reduces risk of PK rejection? Yes No
Generic available? Yes No
…and the badRestasis vs Steroids: The good news…
24
Restasis
![Page 25: What is Restasis - aao.org](https://reader033.vdocuments.us/reader033/viewer/2022061306/629d8aa9b733c83875598a2c/html5/thumbnails/25.jpg)
Q
Prednisoloneacetate 1% Restasis
Cataractogenic? Yes No
Inhibits epithelial healing? Yes No
Glaucomagenic? Yes No
Potentiates HSV infection? Yes No
Increases risk of fungal
keratopathy?Yes No
Prednisolone acetate 1% Restasis
Expensive? No Yes
Slow to work? No Yes
Stings/burns? No Yes
Reduces risk of PK rejection? Yes No
Generic available? Yes No
…and the badRestasis vs Steroids: The good news…
25
Restasis
![Page 26: What is Restasis - aao.org](https://reader033.vdocuments.us/reader033/viewer/2022061306/629d8aa9b733c83875598a2c/html5/thumbnails/26.jpg)
A
Prednisoloneacetate 1% Restasis
Cataractogenic? Yes No
Inhibits epithelial healing? Yes No
Glaucomagenic? Yes No
Potentiates HSV infection? Yes No
Increases risk of fungal
keratopathy?Yes No
Prednisolone acetate 1% Restasis
Expensive? No Yes
Slow to work? No Yes
Stings/burns? No Yes
Reduces risk of PK rejection? Yes No
Generic available? Yes No
…and the badRestasis vs Steroids: The good news…
26
Restasis
![Page 27: What is Restasis - aao.org](https://reader033.vdocuments.us/reader033/viewer/2022061306/629d8aa9b733c83875598a2c/html5/thumbnails/27.jpg)
Q
Prednisoloneacetate 1% Restasis
Cataractogenic? Yes No
Inhibits epithelial healing? Yes No
Glaucomagenic? Yes No
Potentiates HSV infection? Yes No
Increases risk of fungal
keratopathy?Yes No
Prednisolone acetate 1% Restasis
Expensive? No Yes
Slow to work? No Yes
Stings/burns? No Yes
Reduces risk of PK rejection? Yes No
Generic available? Yes No
…and the badRestasis vs Steroids: The good news…
27
Restasis
![Page 28: What is Restasis - aao.org](https://reader033.vdocuments.us/reader033/viewer/2022061306/629d8aa9b733c83875598a2c/html5/thumbnails/28.jpg)
A
Prednisoloneacetate 1% Restasis
Cataractogenic? Yes No
Inhibits epithelial healing? Yes No
Glaucomagenic? Yes No
Potentiates HSV infection? Yes No
Increases risk of fungal
keratopathy?Yes No
Prednisolone acetate 1% Restasis
Expensive? No Yes
Slow to work? No Yes
Stings/burns? No Yes
Reduces risk of PK rejection? Yes No
Generic available? Yes No
…and the badRestasis vs Steroids: The good news…
28
Restasis
![Page 29: What is Restasis - aao.org](https://reader033.vdocuments.us/reader033/viewer/2022061306/629d8aa9b733c83875598a2c/html5/thumbnails/29.jpg)
Q
Prednisoloneacetate 1% Restasis
Cataractogenic? Yes No
Inhibits epithelial healing? Yes No
Glaucomagenic? Yes No
Potentiates HSV infection? Yes No
Increases risk of fungal
keratopathy?Yes No
Prednisolone acetate 1% Restasis
Expensive? No Yes
Slow to work? No Yes
Stings/burns? No Yes
Reduces risk of PK rejection? Yes No
Generic available? Yes No
…and the badRestasis vs Steroids: The good news…
29
Restasis
![Page 30: What is Restasis - aao.org](https://reader033.vdocuments.us/reader033/viewer/2022061306/629d8aa9b733c83875598a2c/html5/thumbnails/30.jpg)
A
Prednisoloneacetate 1% Restasis
Cataractogenic? Yes No
Inhibits epithelial healing? Yes No
Glaucomagenic? Yes No
Potentiates HSV infection? Yes No
Increases risk of fungal
keratopathy?Yes No
Prednisolone acetate 1% Restasis
Expensive? No Yes
Slow to work? No Yes
Stings/burns? No Yes
Reduces risk of PK rejection? Yes No
Generic available? Yes No
…and the badRestasis vs Steroids: The good news…
30
Restasis