Welcome to Bio181L!

Section 25, Room 420

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2What 181L is

• Thinking, Understanding, Investigating, Evaluating

• Not arrive, assembly line, leave

• RIGHT NOW: Read pp. ix & xi in lab manual

• Not sync’ed with most lecture sections, but internally coherent & mutually reinforcing

380% of success is just showing up*

• Absences must be excused by Asya Roberts in BSE109 prior to making up. Contact her as soon as possible. Really.

Her email: asya@email.arizona.edu

• Late is absent. Leaving early is absent.

• Labs cannot be offered week after they are delivered; Avoid missing a lab

• Missing 2 labs => you’ll be dropped from the course--excused or otherwise (b/c you’ll have little shot at learning what you need)

*--Woody Allen

Absences and Late Work

READ THE SYLLABUS TONIGHT IF YOU HAVEN’T ALREADY!!!

•http://blc.arizona.edu/courses/181Lab/ => Syllabus

If you only read one part of it make it this:

•http://blc.arizona.edu/courses/181Lab/ => Syllabus => Absences and late work

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5Policies & Grading• Syllabus (Linked on course homepage)

• Assignments

• On-line assessments/tutorials (10%)

• In-class quizzes (15%)

• Lab assignments (LABAs--Lab Activity Based Assignments) (50%)

• Lab Projects & reports (combine to 25%)

• Every assignment is posted & reported on basis of 100%

• For electronic assignments, log in again to see your recorded score

• Also reported to you at the end

Plagiarism and Cheating• Plagiarism:

• This is a heinous crime

• Read page xiii in the Lab Manual

http://deanofstudents.arizona.edu/studentcodeofconduct

• If you’re in doubt, ask me BEFORE you turn something in

• I will drop you from the class and recommend your expulsion from the university if you plagiarize

• Cheating:

• Keep your eyes on your quizzes

• Its not worth it

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Success in my Class• Ask questions often

• Read the Lab before class (Highlight important info)

• Be prepared, on time, and behave yourself

• No texting or calling in my class (take it outside, or else I’ll give you a 0% on the daily quiz)

• Clean up your work station after each lab (untidy work stations will result in 10% deduction on daily quiz)

• Ask me for help whenever you can

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8About me...My name is Jameson Cumsky, but you can call me “Jamie”

I’m an undergraduate, a “super-senior”, majoring in psychology and minoring in biochemistry and MCB. I’m planning on going to medical school to become a psychiatrist. My favorite music is stuff from the 90’s

Email: jcumsky@email.arizona.edu

Office Hours: Koffler 209, Fridays 3-5PM

9My Webpage• Get there via homepage* => Instructors => 25

*http://blc.arizona.edu/courses/181Lab (Lab Man yellow page)

10Web page operation

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About you• Introductions!

Name?

Year in school?

Major/minor?

Career/personal goals?

Favorite type of music/artist/video game/tv show?

Meet your neighbors! They’re your group today!

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181 Lab ACCOUNTSGET TO THE COMPUTER!

• Course home page:

http://blc.arizona.edu/courses/181lab (Safari home page)

Click ‘Create Accounts’

NOTE: Do NOT use UANetID psassword!

•Your section number is: 25

• Bio181L_Go is the way to do your work. Browser bad

(I’ll show you how to download that at the end of class!)

Time for Introductions

Share your cards with the class (and I)!

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the Tao of Molecules• How molecules feel & the world they live in

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How? Why?

Primary goals

• Create understanding by observation, reasoning

• Chemical foundations for the course:

• Water & its properties

• non-watery things

• Know molecules as real & tangible things

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16

From The Secret of Scent, Luca Turin p.28

When a journalist asked the great physicist Richard Feynman what single sentence would best encapsulate all science so far if it were to be the sole surviving scrap of all we knew, he replied, “The world is made of atoms.”

When a journalist asked the great physicist Richard Feynman what single sentence would best encapsulate all science so far if it were to be the sole surviving scrap of all we knew, he replied, “The world is made of atoms.”

17Atoms: They’re how life works

The 4 types of biological molecules:

•Nucleic Acids (DNA, RNA): C, H, N, O, P, [Mg++]

•Carbs: C, H, O

•Proteins: C, H, N, O, (S), (P), [traces]

•Lipids (Membranes, Hormones): C, H, N, O, P, (S)

What cannot be done with assemblages of these atoms* cannot be done by living organisms, nor their

cells, nor their spit, etc.*OK, fine, there’s the occasional role for Ca++, etc.

“S.P.O.N.C.H.”

18Who am I?• At birth, # protons = # electrons

• Atoms seek completion, which means outermost electron set = 8 (hydrogen, helium it’s just 2)

Freeman Fig. 2.1a

19Coloring your world

Electronegativity 20

Jargon• Covalent bond: The sharing of electrons between atoms,

forming a molecule.

• Polarity: Having an unequally distributed charge. A quality of molecules. Molecules are polar if they have unevenly distributed charge, non-polar if they have evenly distributed charge.

• Polar interactions/Hydrogen interactions: The attraction of molecules to each other on the basis of unevenly distributed charge

• Non-polar interaction/Hydrophobic interaction: The interaction between non-polar molecules as a result of there exclusion from polar interactions.

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22Views of Water

H2O

HO

H

See lab manual, p. 0-3

(There will be a test)+

+

-

23How to draw molecules

Carbon Hydrogen Oxygen Nitrogen

Figure is from Lab Manual p. 0-5

24Interacting with H2O

To your StructViewers!Desktop => Bio181L_Go

NOTE: You’ll need to download this on your personal computer in order to do the homework!

Homepage => Course Software => Bio181L_Go

Doing it

Computers, stations

Tao_MCB181L (on desktop)

Your assigned names:

Charizard Zapdos

Venusaur Moltres

Blastoise Magikarp

Articuno

Write your group names down!!!

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26Evaporation• First things first--what is it? What’s going on in terms of

molecules

• Experiment: Ethanol and water on your arm: which is cooler & why?

• Prediction: based on molecular weight, which should evaporate more quickly--H2O (2 x 1 + 1 x 16) or CH3CH2OH (5 x 1; 2 x 12; 1

x 16)

• If not, why not?

• Salt--ever tasted your sweat? Or anybody else’s for that matter?

• What benefit might there be to adding NaCl to water that you are intending to evaporate?

27Clean up!

• Oil waste in the hood

• ethanol waste in the sink

• anything too messy wadded up and discarded

• Wipe down lab areas and leave them in the same (or better) condition you found them in!

TA-lead discussions 28

• Structures of oil and water• Streaming oil and water• Dissolving salt – or not• Floating a staple• Why does pepper “flee” the scene of a

detergent?• Two kinds of drops versus two kinds of

surfaces• Alcohols, water, and salt: blending and

separating• Density versus hydrophobicity• Sweatin’ to the oldies – NEXT SLIDE YO

29What’s an Assessor?

=>Chatting<=

30What’s vocabulary homework?

• EITHER both versions of the crossword exercise

• OR VocabuWary with a better than threshold score

• For “Atoms & Molecules”, F12, that’s 60,000

• Errors count off. Slowness counts off.

Homework due 10 p.m. before

lab• Read Syllabus: http://blc.arizona.edu/courses/181Lab/ => Syllabus

• Download Bio181L_Go on personal computer: This is the program you will use to do homework!

• Assessor: 181 Intro ’12

• Vocab: Atoms/Mols: CrossWord (both versions) or VocabuWary

• Assessor: Molecular World Tutorial

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Next week’s quiz will includeConcepts from today

Atom colorsDeducing partial charges

Lab Manual Ch. 2

In Depth!