Skeletal Muscle Tissue: Worksheet 2FOR THIS WORKSHEET:

I WANT YOU GUYS TO PRING THIS OUT, AND USE MY BLANK TAMPLATE TO STUDY, AND CONTINUES TO DOTHIS UNTIL YOU UNDERSTAND THE WHOLE PROCESS!! ** FIND A STUDY PARTNER, AND TAKE TURNS REPEATING THE WHOLE NEUROMUSCULAR JUMPTION> ACTION POTENTIAL> PORPIGATION> T-TUBULES> CA+ VOLATEG GATED CHALLES> SARCOPLASM> CA+ BINDS TO TROPONIN> TROPOMYOSIN IS MOVED OFF THE MYOSIN HEAD BIND SITES> AND THE WHOLE CROSS BRIDGE FORMATION > ATP>ADP.PHOSPHATE> AND UNDERSTAND THAT THE CONTRACTIONS CONTINUES TO HAPPEN, As LONG as the CALCIUM is STILL attached to the TROPONIN on the TROPOMYOSIN binding COMPLEX!!!!!!!!!!!, and once the calcium is RELEASED, the myosin head detach, calcium goes back to the sarcoplasmic reticulum, and there is a ABSOLUTE REFRACTORY PERIOD, that INHIBITS another contraction to occur so that the muscle can fully get back to RESTING MEMBRANE POTENTIAL. And then the WHOLEEEE cycle starts over again: STARTING from the MOTOR NEURON AP Voltage gates Ca+ channels open ACH vesicles leave EXOCYTISIS ACH ligand gates channels are activated NA+ moves into the cell, and Propagation of Action Potential is not PROPERGATING across the Sarcoplasm.

REMEMBER: a SARCOLEMMA and a SARCOMERE are DIFFERE

Sarcolemma is the WHOLE muscle FIBRIL (not fiber)

Sarcomere is an individual Z-Z disc.( multiple Sarcomeres make up a muscle fiber)

Actin and Myosin NEVER SHORTEN!!!!!!!!!!

Only the SARCOMERE contracts and relaxes.

Don't mix this up!!

Also, Check out:

Khanacadamy on YOUTUBE: Search Neuromuscular junction, and Search Cross bridge formation of skeletal muscle tissues.

You will be happy you did this.

Skeletal Muscle Tissue: Worksheet 2BLANK TEMPLATE: Use this to Test yourself to see how well you know the system, parts that are used during this process.

ITS NOT HARD!!!!!! I promise, just take 20 minutes to watch a video, and I PROMISE this will help you.

Skeletal Muscle Tissue: Worksheet 2

Skeletal Muscle Tissue: Worksheet 2NEUROMUSCULAR JUNCTION: Match LETTER to #

EXCITATION-CONTRACTION COUPLING

1. axon terminal of motor neuron -> A, Motor neuron is the NERVE that INTERVATES each MUSCLE FIBER

2. synaptic vesicle: --Aa. What activates these?

-CALCIUM3. What way of Transport to these vesicles leave?

-EXOCYTOSIS4. synaptic cleft: -C

a. What ENZYME becomes present here?i. AcHase

5. Ach: A (Inside Vesicles are the ACH)a. What is the name of these binding sites?

i. Ligand Gated Ach Binding sites

6. Once the skeletal muscle receives the Action potential what type of voltage gated channels are activated?

Ca+ voltage gate channelsa. Where are they located? Motor Neuron

1. Action potential is propagated along the sarcolemma and down the T tubules.

- A2. The SR is stimulated to release calcium ions.

- Ba. Calcium moves through the Sarcoplasmb. Between B and C, the CALCIUM binds to

the (yellow) Troponin.3. Calcium binds to troponin and removes the

blocking action of tropomyosin.- Tropomyosin MOVING allows the

Myosin heads to BIND to the ACTING (myosin BIND sites)

4. Cross bridge formation occurs and the contraction mechanism is initiated.

a. Onces the Actin site and Myosin HEAD bind, Contraction is Ready to occure. (ATP IS NEEDED). REMBER, al that ATP means is AdaninTRIphosphate breaks down to adaninDIphosphate through HydroloSIS (splitting is Hydrogen BONDS)

Skeletal Muscle Tissue: Worksheet 2

 MATCH LETTER TO NUMBER

1. cross bridge detachmentC

2. the power stroke or working stroke B

3. cross bridge formation A

4. cocking of myosin head D