Curriculum Vitae

Sanaa K. Bardaweel

BSc, MSc, PhD Pharmacy

Associate Professor of Medicinal Chemistry

Former Assistant Dean for Pharmaceutical Field Training Affairs

Department of Pharmaceutical Sciences

School of Pharmacy

University of Jordan

Amman 11942

Jordan

Tel: 00962-6- 5355000. ext. 23318 (Work), Mobile : 00962775190831

Fax: 00962-6-5300250 Faculty, 00962-6- 5355511-22 University

Email: s.bardaweel@ju.edu.jo

Home Page http://eacademic.ju.edu.jo/s.bardaweel/default.aspx

GENERAL INFORMATION

Date of Birth : April 22ed, 1981Place of Birth : Jarash - Jordan.Nationality JordanianMarital Status : Married, with four children

EDUCATION

Bachelor of Science in Pharmacy (1999 – 2004), Excellence

University of Jordan

Amman, Jordan

Master of Science in Pharmaceutical Sciences (2004-2006), Excellence

Thesis Title, In vitro evaluation and cytocompatibality of natural polymers for

local/systemic delivery of macromolecules

Advisor: Professor Aiedeh, Khalid

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University of Jordan

Amman, Jordan

Doctor of Philosophy in Medicinal Chemistry (2006-2010), Excellence

Thesis Title, Defining the Catalytic and Kinetic Mechanism and Natural Function of the

Highly Conserved Acyl-AMP Hydrolase, HINT1

Advisor: Professor Carston R.Wagner

University of Minnesota

Minneapolis, USA

LANGUAGES

Arabic Mother Tongue

English Excellent

Greek Very good

French Good

Russian Fair

POSITIONS AND ACADEMIC APPOINTMENTS

2015-present Associate Professor of Medicinal Chemistry, The University of

Jordan, School of Pharmacy, Amman.

September 2016-2017 Dean Assistant for Pharmaceutical Field Training, The

University of Jordan, School of Pharmacy, Amman.

2011-2015, Assistant Professor of Medicinal Chemistry, The University of Jordan,

School of Pharmacy, Amman.

2007-2010, Research Assistant, Medicinal Chemistry Department, University of

Minnesota, Minneapolis, MN.

2004-006, Instructor, Teaching Assistant, The University of Jordan, School of

Pharmacy, Amman.

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HONORS AND AWARDS

1999-2004 Scientific Achievement Scholarship, Ministry of Higher Education

Amman, Jordan.

2006 The University of Jordan Honor Award, Graduates.

2006-2007 Ph.D. Full scholarship, The University of Jordan.

2007-2010 Ph.D. Scholarship, The University of Minnesota.

2010 The University of Minnesota Excellence Award for Graduate Students.

PROFESSIONAL ORGANIZATION MEMBERSHIP

Cancer Epigenetics Society The Organization for Women in Science for the Developing World (OWSD). American Chemical Society (ACS)

American Association of Pharmaceutical Sciences (AAPS)

Jordan Society for Scientific Research (JSSR)

The Jordanian Pharmaceutical Association

Scientific Committee at The Jordanian Pharmaceutical Association

Generic Drug Registration Committee in Jordanian Food and Drug Administration

(JFDA).

School of Pharmacy board member.

Scientific Research Committee (School of Pharmacy -JU)

Accreditation and Quality Assurance Committee (School of Pharmacy -JU)

Social Activities Committee (School of Pharmacy -JU)

Community Service Committee (School of Pharmacy -JU)

General Safety Committee (School of Pharmacy -JU)

Conferences and Seminars Committee (School of Pharmacy -JU)

Resources and Equipment’s Committee (School of Pharmacy -JU) Pharmaceutical Field Training Committee (School of Pharmacy -JU) Academic Curriculum Committee (School of Pharmacy -JU) رابطة األكاديميات األردنيات

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PROFESSIONAL QUALIFICATION

Multidisciplinary background in molecular biology techniques: Expertise in DNA

cloning, DNA mutagenesis, protein characterization, enzymatic assay, in vitro cell

based assays.

Proficient in modern analytical techniques: HPLC, Size Exclusion Chromatography,

Western Blot, PCR, NMR, Mass Spectrometry.

Experience in multistep synthesis, purification and characterization of organic

compounds.

Familiar with professional computational softwares: ChemDraw, SciFinder, PyMOL,

etc.

Accomplished the cloning, site-directed mutagenesis, over-expression, refolding and

purification of multiple proteins.

Developed a method to study two proteins interaction via radialabeling assays.

Developed a method to study the bacterial phenotype associated with the “Y” genes;

genes with unknown functions.

Eexperience in Tissue and Cell culture techniques.

TEACHING EXPERIENCE AT THE UNIVERSITY OF JORDAN

Advanced Medicinal chemistry (MSc level)

Advanced Instrumental Analysis (MSc level)

Advanced Organic Chemistry (MSc level)

Drug analysis – Practical (Master level)

Macromolecule-ligand binding (PhD level)

Drug analysis and Characterization (MSc level)

Medicinal chemistry I (Undergraduate level)

Medicinal chemistry II (Undergraduate level)

Medicinal chemistry III (Undergraduate level)

Instrumental analysis (Undergraduate level)

Analytical Chemistry (Undergraduate level)

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Phyto-chemical Analysis (Undergraduate level)

Seminar in pharmaceutical Sciences (Undergraduate level)

Phyto-chemical Analysis-Practical (Undergraduate level)

Medicinal chemistry- Practical (Undergraduate level)

Instrumental analysis- Practical (Undergraduate level)

Analytical Chemistry – Practical (Undergraduate level)

Phyochemistry– Practical (Undergraduate level)

Organic Chemistry – Practical (Undergraduate level)

NATIONWIDE ACTIVITIES AND CONSULTATION

Associate Editor of:

UK Journal of Pharmaceutical and Biosciences (UKJPB)

Journal of Innovations in Pharmaceuticals and Biological Sciences

Annals of Chromatography and Separation Techniques

Referee for the International Journals of

BMC Complementary and Alternative Medicine

African Journal of Pharmacy and Pharmacology

The Jordan Journal Pharmaceutical Sciences

Journal of Women’s Health, Issues & Care

Natural products research.

Acta Pharmaceutica.

Advances in Biochemistry

European Journal of Molecular Biology

International Journal of Advances in Pharmacy, Biology and Chemistry

Arch der pharmazie

Journal of medicine and medical research

The European Journal of Contraception and Reproductive Health Care

African Journal of Traditional, Complementary and Alternative Medicines

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International Journal of Nanomedicine.

Letters in Drug Design & Discovery.

International journal of fertility & sterility

Phytotherapy Research

Medicinal Chemistry Reseach

Anti-Cancer Agents in Medicinal Chemistry

Communications Biology- Nature

MASTER STUDENT SUPERVION

Chemical composition of the volatile oil from leaves of four cultivars of Jordanian

Oleo europaea L. and evaluation of antioxidant and anticancer activities of the

aqueous extract. MSC Graduation Thesis. Faculty of Pharmacy, University of Jordan.

June 2014(Co-advisor).

Metformin: determinants of its beneficial role in ER-positive breast carcinoma growth

inhibition. MSC Graduation Thesis. Faculty of Pharmacy, University of Jordan.

December 2014 (Supervisor).

Quantitative Analysis of the Anti-Proliferative Activity of Combinations of Selected

Metal-Chelating Agents and Clinically Used Non-steroidal Anti-inflammatory Drugs.

MSC Graduation Thesis. Faculty of Pharmacy, University of Jordan. April 2015

(Supervisor).

Towards the discovery of new inhibitors against the highly conserved protein ppk1

followed by validation against relevant bacterial species. MSC Graduation Thesis.

Faculty of Pharmacy, University of Jordan. December 2015 (Supervisor).

Discovery of New Potent Dual Inhibitors Targeting Melanin-Concentrating Hormone

Receptor 1(MCH-R1) and Ghrelin Receptor as Novel Promising Anti-obesity by

using Computer Aided Drug Design Methodologies. PhD Graduation Thesis. Faculty

of Pharmacy, University of Jordan. December 2015 (Co-advisor).

The Association of CYP2D6 enzyme polymorphism alleles *4*10 and *17 frequency

with prognostic factors and disease - free survival in Jordanian women with Breast

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Cancer who were treated with Tamoxifen. MSC Graduation Thesis. Faculty of

Pharmacy, University of Jordan. December 2017 (Supervisor).

Characterization of the role of proton pump inhibitors as proliferation suppressors and

chemosensitizers in breast cancer cell lines. MSC Graduation Thesis. Faculty of

Pharmacy, University of Jordan. December 2017 (Supervisor).

Assessment of 1,25-dihydroxyvitamin D3 antiproliferative effects on Different

Molecular Subtypes of Breast Cancer: An in vitro Study. MSC Graduation Thesis.

Faculty of Pharmacy, University of Jordan. March 2018 (Supervisor).

MEMBERSHIP IN GRADUATE EXAMINATION COMMITTEES

MSc thesis: Hamsa Alakad. "Investigating physicians’ perception of pharmaceutical

trade names in Jordan’s private market: simulated and real-world setting

approaches". MSc Graduation Thesis. Faculty of Pharmacy, University of Jordan.

May 2014.

MSc thesis: Hanan S.Alamaddin.” The use of comparative intramolecular contact

analysis to build valid pharmacophore model(s) against soluble epoxide hydrolase

towards development of potential anti-inflammatory agents.” ". MSc Graduation

Thesis. Faculty of Pharmacy, University of Jordan. July 2013.

MSc thesis: Rasha Khalil Zamel. “The effect of membrane receptors on cellular

behavior of breast cancer cell lines.” MSc Graduation Thesis. Faculty of Medicine,

University of Jordan. December 2014.

MSc thesis: Musab Mahmoud Sadeh. “Pharmacophore-based screening and

identification of novel phosphoinositide 3-kinase (PI3Ka) inhibitors.” MSc

Graduation Thesis. Faculty of Pharmacy, University of Alzytoona. December 2014.

MSc thesis: Safá Ismail Amayreh. “The use of ligand-based modeling followed by in

vitro assay for the discovery of new spleen tyrosin kinase inhibitors.” MSc

Graduation Thesis. Faculty of Pharmacy, University of Jordan. May 2015.

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MSc thesis Noor Abualhaija’. “Ligand-based modeling towards discovery of new

inhibitors against the oncogenic protein BCL-2 followed by validation against

relevant cancer cell line. MSc Graduation Thesis. Faculty of Pharmacy, University

of Jordan. August 2015.

MSc thesis Haneen Khaled Mahmoud. “Screening and size effect investigation of

nicotinic acid analogues as potential carbonic anhydrase III inhibitors to treat

hyperlipidemia.” MSc Graduation Thesis. Faculty of Pharmacy, University of

Jordan. August 2015.

MSc thesis Hadeel Hudaib. “Chemical composition of the volatile oil from leaves of

four cultivars of Jordanian Oleo europaea L. and evaluation of antioxidant and

anticancer activities of the aqueous extract” MSc Graduation Thesis. Faculty of

Pharmacy, University of Jordan. August 2015.

MSc thesis Shada Alabed. “Computer aided drug design and discovery of new

Fibroblast Growth Factor Receptor 1 inhibitors (FGFR1) followed by in vitro assay.

MSc Graduation Thesis. Faculty of Pharmacy, University of Jordan. August 2015.

MSc thesis Islam Bardaweel. Metformin: determinants of its beneficial role in ER-

positive breast carcinoma growth inhibition.” MSc Graduation Thesis. Faculty of

Pharmacy, University of Jordan. December 2015.

MSc thesis Layth Shdeifat. “The use of computer aided ligand based modeling

followed by in vitro assay for the discovery of new Epidermal Growth Factor

Receptor (EGFR) inhibitors.” MSc Graduation Thesis. Faculty of Pharmacy,

University of Jordan. May 2016.

MSc thesis Mohammed Badran. “Synthesis and Biological Evaluation of Novel

Phthalimide Derivatives Compounds as Kinaes Inhibitors.” MSc Graduation Thesis.

Faculty of Pharmacy, University of Jordan. May 2016.

MSc thesis Ameerah Said Mahmoud. “Optimization and synthesis of benzoin

derivatives as PI3La inhibitors”. MSc Graduation Thesis. Faculty of Pharmacy,

University of Alzytoona. June 2016.

PhD thesis Reem AbuTayeh. “Implementation of computer aided drug design

methodologies for the discovery of novel small molecule inhibitors of FMS-like Page 8 of 24

tyrosine kinase (Flt3)”. PhD Graduation Thesis. Faculty of Pharmacy, University of

Jordan. June 2016.

MSc thesis Saja Adel Saleh Alassaf. “Implementation of docking-based comparative

intramolecular contacts analysis (db-cica) for the discovery of polo-like kinase 1

(plk1) inhibitors as potential anticancer agents”. MSc Graduation Thesis. Faculty of

Pharmacy, University of Jordan. November 2016

MSc thesis Dana Otoum. “Characterization of immunomodulatory effect of

Gemifloxacin in vivo and in vitro in aBalb-c mice” MSc Graduation Thesis. Faculty

of Pharmacy, University of Jordan. April 2017.

MSc thesis Rasha Bashatweh. “Towards the discovery of new inhibitors against the

highly conserved protein ppk1 followed by validation against relevant bacterial

species”. MSc Graduation Thesis. Faculty of Pharmacy, University of Jordan. April

2017.

PhD thesis Safa Dawood. “Discovery of Novel Small Molecule Antagonists of

Chemokine Receptor 4 (CXCR4) as Compounds of Therapeutic Potential for

Autoimmune Diseases using Computer Aided Design” PhD Graduation Thesis.

Faculty of Pharmacy, University of Jordan. April 2017

MSc thesis Kamal AlShami. “Crizotinib Inhibits Growth and Migration of Breast

Cancer Cells and Synergizes with Chemotherapy.” MSc Graduation Thesis. Faculty

of Pharmacy, Jordan University of Science and Technology JUST. May 2017.

MSc thesis Ghada Tuffaha. “Computer-aided drug design and discovery of new c-

JUN n-terminal kinase 3 receptor inhibitors (JNK3) via structure based modelling

followed by in vitro assay”. MSc Graduation Thesis. Faculty of Pharmacy,

University of Jordan. December 2017.

MSc thesis Ahmad Alrawi “Anticancer and immunomodulatory activities of

Jordanian Citrullus colocynthis”. MSc Graduation Thesis. Faculty of Pharmacy,

Applied Science Private University, Jordan. December 2017.

MSc thesis Marwah Azayzah “evaluation of the effect of calcium sensing receptor

blocking by NPS2143 on proliferative, apoptosis, migratory and invasive potential of

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breast cancer cells” MSc Graduation Thesis. Faculty of Pharmacy, Jordan University

of Science and Technology JUST, May 2018.

MSc thesis Raed Al-Hweiyyan. “ Determination of the anticancer activity of selected

pure compounds of natural origin: possible involvement of phosphatase of

regenerating liver enzyme” ”. MSc Graduation Thesis. School of Pharmacy,

University of Jordan. July 2018.

MSc thesis Worood Ihraiz “Characterization of the role of proton pump inhibitors as

proliferation suppressors and chemosensitizers in breast cancer cell lines”. MSc

Graduation Thesis. School of Pharmacy, University of Jordan. July 2018.

GRANTS AND FUNDED PROJECTS

S. Bardaweel, M. Hudaib and K. Tawaha. Project title: "In Vitro Evaluation of

Antibacterial, Antifungal, and Anticancer Activities of Essential Oils from Six

species of Eucalyptus". (13000 $, Deanship of Academic research, University of

Jordan-2012).

S. Bardaweel, R. Abu-Dahab and R. Darwish. Project title: " D-amino acids:

investigation of possible toxicity in bacteria and cancer cells." (37000 $, Deanship of

Academic research, University of Jordan-2011).

S. Bardaweel, M. Hudaib and K. Tawaha. Project title:" In vitro evaluation of

antibacterial, antifungal, and anticancer activities of essential oils from selected

aromatic medicinal plants in Jordan (10000 $, Deanship of Academic research,

University of Jordan-2014).

S. Bardaweel, Khaled Al-fawares, Yusuf Al-Hiari, Mohammad Al-Zweiri, and

Mohammad Khafar. Project title:" Purification of Pathogenesis Determinant Proteins

for the Identification of Novel Antimicrobial Targets: Polyphosphate Kinase 1

Active Site Characterization”. (129000$, Scientific Research Support Fund, The

Ministry of Higher Education, Jordan-2014).

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S. Bardaweel and Rana Abu-Dahab. Project title: “Metformin: A metabolic

disruptor and anti-diabetic drug to target human Breast Cancer.” (21000 $, Deanship

of Academic research, University of Jordan-2016).

S. Bardaweel. Project title: “Awareness, utilization, behaviors and attitudes towards

oral contraception among women in refugee camps in Jordan” 6500$, Deanship of

Academic research, University of Jordan-2016).

S. Bardaweel. Project title: “The Use of Metformin Antidiabetic Drug as

Chemosensitizer and Cancer Metastasis Inhibitor.” King Abdullah II Design &

Development Bureau – KADDB-2017, 7500$.

S. Bardaweel. Project title: “Purification of Pathogenesis Determinant Proteins for

the Identification of Novel Antimicrobial Targets: Polyphosphate Kinase 1 Active

Site Characterization” 16600 $, Deanship of Academic research, University of

Jordan 2018.

S. Bardaweel. Project title: “Quantitative Analysis of the Anti-Proliferative Activity

of Combinations of Selected Metal-Chelating Agents and Clinically Used Non-

steroidal Anti-inflammatory Drugs” 7000$, Deanship of Academic research,

University of Jordan 2018.

Dima A. Sabbah, Sanaa K. Bardaweel, Kamal Sweidan, Reema Abu Khalaf, Eveen

Al-Shalabi, Ghassan Abu Sheikha, Tariq Al Qirim Project title: “Design, Synthesis,

and Biological Evaluation of PI3Kα and EGFR Inhibitors Targeting Colon and

Breast Cancer, 2018-2020” Scientific Research Support Fund, The Higher Education

Ministry of Jordan, 79500$

Dima A. Sabbah, Sanaa K. Bardaweel, Kamal Sweidan, Reema Abu Khalaf, Eveen

Al-Shalabi, Ghassan Abu Sheikha, Tariq Al Qirim Project title: “Design, Synthesis,

and Biological Evaluation of PI3Kα and EGFR Inhibitors Targeting Colon and

Breast Cancer, 2018-2020” Al-Zaytoonah University of Jordan, the Deanship of

Scientific Research 28000$.

PODIUM AND POSTER PRESENTATIONS:

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Second Annual Meeting and International Conference of the Consortium for

Research in Political Theory (CRIPT), “The Crisis: Future Prospects on Politics,

Culture, and Governance” Oral presentation: Impediments to use of oral

contraceptives among refugee women in camps, Jordan. (Sanaa K. Bardaweel,

Amal Akour, Aseel Khawaldeh). Ankara, Turkey, July 2018.

oral presentation السابع الطبي البلقاء Currentمؤتمر knowledge, attitude, and

patterns of oral contraceptives utilization among women in Jordan (Sanaa K.

Bardaweel, Amal Akour) August 2017.

Al-Zaytoonah University of Jordan and the University of Toledo International

Pharmaceutical Conference (ZTIPC 2017) “New Horizons in Pharmaceutical

Research”, November 29-30th 2017, Amman, Jordan. Oral Presentation:

Pharmacophore Based-Design of Phosphoinositide-3-Kinase (PI3Kα) Inhibitors.

Dima A. Sabbah, Bayan Hishmah, Kamal Sweidan, Sanaa Bardaweel, Murad

AlDamen, Haizhen A. Zhong, Reema Abu Khalaf, Ameerah (Hasan Ibrahim), Tariq

Al-Qirim, Ghassan Abu Sheikha , Mohammad S. Mubarak

Al-Zaytoonah University of Jordan and the University of Toledo International

Pharmaceutical Conference (ZTIPC 2017) “New Horizons in Pharmaceutical

Research”, November 29-30th 2017, Amman, Jordan. Poster Presentation: Structure-

Based Design, Synthesis, and Biological Evaluation of Benzoin Schiff Bases as

Potential Antitumor Agents. Fatima Al-Tarawneh, Dima A. Sabbah, Wamidh Talib,

Kamal Sweidan, Sanaa Bardaweel, Eveen Al-Shalabi, Haizhen A. Zhong, Ghassan

Abu Sheikha, Reema Abu Khalaf, Mohammad S. Mubarak

The 20th Congress of the Arab Association of the Faculties of Pharmacy and the

5th International Conference of the Jordanian Faculties of Pharmacy and the

2nd International Conference of the Faculty of Pharmacy at Isra University. Oral

presentation: Metformin: Determinants of its Beneficial Role in ER-positive Breast Carcinoma Growth Inhibition. (Sanaa K. Bardaweel,

Rana Abudahab). Amman – Jordan from 7-9 November 2017.

The Twentieth Congress of the Arab Association of the Faculties of Pharmacy The

Fifth International Conference of the Jordanian Faculties of Pharmacy The Second Page 12 of 24

International Conference of the Faculty of Pharmacy at Isra University, Isra

University 7-9 November 2017. Oral presentation: Metformin: Determinants of its Beneficial Role in ER-positive Breast Carcinoma Growth Inhibition. (Sanaa K. Bardaweel, Rana Abudahab).

The 6th International Jordanian Congress of Allergy and Immunology, July 28th -30th

2017, Chairperson and Speaker. Oral presentation: Metformin: Determinants of its Beneficial Role in ER-positive Breast Carcinoma Growth Inhibition. (Sanaa K. Bardaweel, Rana Abudahab).

Erasmus exchange program University of Ataturk April 30 th –May 5th 2017. Oral

presentation: Towards the discovery of new inhibitors against the highly conserved

protein ppk1 followed by validation against relevant bacterial species. Rasha

Bashatweh, Sanaa Bardaweel, Mohammad Khanfar.

Erasmus exchange program University of Ataturk April 30 th –May 5th 2017. Oral

presentation: Metformin: Determinants of its Beneficial Role in ER-positive Breast Carcinoma Growth Inhibition. (Sanaa K. Bardaweel,

Rana Abudahab).

ASU Second Symposium "Recent Trends in Postgraduate Research", April 15-

16th 2017, Amman, Jordan. Oral presentation: Towards the discovery of new

inhibitors against the highly conserved protein ppk1 followed by validation against

relevant bacterial species. Rasha Bashatweh, Sanaa Bardaweel, Mohammad

Khanfar

ASU Second Symposium "Recent Trends in Postgraduate Research", April 15-

16th 2017, Amman, Jordan. Poster Presentation: N-substituted- 4-hydroxy-2-

quinolone-3-carboxamides as Potential PI3Kα. The Poster is awarded the Third

Place in Postgraduate Poster Competition. Ameerah (Hasan Ibrahim), Bayan

Hishmah, Dima A. Sabbah, Kamal Sweidan, Sanaa Bardaweel, Murad AlDamen,

Reema Abu Khalaf, Haizhen A. Zhong, Tariq Al-Qirim, Ghassan Abu Sheikha.

Gordon Research Conference: Mammalian DNA Repair, February 19-24th, 2017,

Ventura, CA, USA. Poster Presentation: Structure-Based Drug Design, Synthesis, X-

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ray Crystallography, and Biological Evaluation of N-Substituted-4-Hydroxy-2-

Quinolone-3-Carboxamides as PI3Kα Inhibitors. Ghassan Abu Sheikha, Dima A.

Sabbah, Bayan Hishmah, Kamal Sweidan, Sanaa Bardaweel, Murad AlDamen,

Haizhen A. Zhong, Ameerah (Hasan Ibrahim), Reema Abu Khalaf, Tariq Al-Qirim

The 19th International Conference on Drug Development and Therapeutics (ICDDT

2017)/, KSA, Jeddah. Oral presentation: Polyphosphate Kinase 1 Active Site

Characterization for the Identification of Novel Antimicrobial Targets. ( Sanaa K.

Bardaweel), January 30-31, 2017.

Horizon 2020 Workshop on Project management. Amman, January 16th, 2017.

Horizon 2020 Workshop on Proposal Writing EU Funding Opportunities. Amman,

December 5th-7th, 2016.

The 18th International Conference on Biochemical Pharmacology and Medicinal

Chemistry (ICBPMC)/ Turkey, Istanbul. Oral presentation: Polyphosphate Kinase

1 Active Site Characterization for the Identification of Novel Antimicrobial Targets.

( Sanaa K. Bardaweel), December 19-20, 2016

The 4th International Conference of the School of Pharmacy and the 2ed Conference

of the Association of faculties of Pharmacy at Jordanian Universities/Jordan,

Amman. Oral presentation: Metformin: Determinants of its Beneficial Role in ER-positive Breast Carcinoma Growth Inhibition.(Sanaa K.

Bardaweel, Rana Abudahab). October 25-28, 2016.

The 4th International Conference of the School of Pharmacy and the 2ed Conference

of the Association of faculties of Pharmacy at Jordanian Universities/Jordan,

Amman. Poster: Current knowledge, attitude, and patterns of oral contraceptives

utilization among women in Jordan (Sanaa K. Bardaweel, Amal Akour). October

25-28, 2016.

The 5th International Conference of the Arab Society for Medical research/Egypt,

Sharm Alshaikh. Oral presentation: Current knowledge, attitude, and patterns of oral Page 14 of 24

contraceptives utilization among women in Jordan. (Sanaa K. Bardaweel, Amal

Akour). October 28-31, 2016.

The 5th International Conference on Pharmaceutical Sciences/ UAE, Dubia. Oral

presentation: Metformin: Determinants of its Beneficial Role in ER-positive Breast Carcinoma Growth Inhibition.(Sanaa K. Bardaweel, Rana

Abudahab). August 2016

The 1st International Medical Conference for Dr. Jamel Al-Totanj Hospital 2016.

Jordan, Sahab. Oral presentation: Current knowledge, attitude, and patterns of oral

contraceptives utilization among women in Jordan. Sanaa K. Bardaweel, July 2016.

The 15th International Congress of the International Society for Ethno-

Pharmacology. Jordan, Petra. Oral presentation: “Studies on the In Vitro

Determination of the Antiproliferative Activity Associated with Chrysanthemum

Coronarium Essential Oil”. (Sanaa K. Bardaweel, Mohammad M. Hudaib, Khaled

A. Tawaha, Rasha M. Bashatwah) May 2015.

Pharmacy Sciences and Practice: An updated Perspective. The University of

Jordan, Faculty of Pharmacy, Jordan, Amman. Poster presentation: D-amino

acids: Antiproliferative effects and mechanistic studies. (Sanaa K. Bardaweel,

Rasha Bashatweh). 2015.

Pharmacy Sciences and Practice: An updated Perspective. The University of

Jordan, Faculty of Pharmacy, Jordan. Poster presentation: Chemical composition

of the volatile oil from leaves of four cultivars of Jordanian Oleo europaea L. and

evaluation of antioxidant and anticancer activities of the aqueous extract. (Hadeel

Hudaib, Muhammad Hudaib, Sanaa K. Bardaweel) 2015.

Session Chair at the XIII International Conference on Pharmacy and

Pharmaceutical Sciences. Dubai, February 2015.

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XIII International Conference on Pharmacy and Pharmaceutical Sciences. Dubai,

UAE. Oral presentation: Antimicrobial, Antioxidant and Free Radical Scavenging

Activities of Essential Oils Extracted from Six Eucalyptus Species. (Sanaa K.

Bardaweel, Mohammad M. Hudaib, Khaled A. Tawaha, Rasha M. Bashatwah.)

2015

The First International Conference on Pharmaceutical and Biological Sciences/ Abu

Dhabi, UAE. Oral presentation: D-amino Acids: Prospects for New Therapeutic

Agents. Sanaa Bardaweel, 2013

The 3ed International Conference of the Faculty of Pharmacy/The University of

Jordan 2012.

The 15th Annual Congress of the Scientific Association of Colleges of Pharmacy

In the Arab World 2012.

 Chemical Biology Initiative Seminars/ USA, Minneapolis. Oral presentation:

Connecting Genotype & Phenotype: Discovering the Essential Role of Histidine

Nucleotide Proteins on E. Coli Alanine Metabolism. 2010. ( Sanaa Bardaweel and

Cartson Wagner)

NIH Chemistry & Biology Interface Training Grant Symposium / USA,

Minneapolis. Oral presentation: Metabolic Phenotype Discovery of  HinT Deleted

Escherichia coli Strain. 2010. (Sanaa Bardaweel, Michael Sadowsky, and Carston

R. Wagner).

Gordon Research Conference on Enzymes and Co-enzymes / USA/Waterville

Valley. Poster: Defining the Catalytic & Kinetic Mechanism and Natural Function

of the Highly. 2009. (Sanaa Bardaweel and Cartson Wagner)

COMPUTER SKILLS

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Excellent command in the use of Microsoft windows and office (Word, Excel,

PowerPoint, Internet, Outlook).

Excellent command of statistical softwares (SPSS).

Excellent command in EndNote. GraphPad Prism, PYMOL

Excellent command in Drug discovery softwares: ChemDraw, ISIS Draw, Science

Finder, and Design Graphics software (Adobe Photoshop, Adobe Illustrator).

PUBLICATIONS

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1. Probing the impact of the echinT C-terminal domain on structure and catalysis (2010) Sanaa

Bardaweel, Pace J, Chou TF, Cody V, Wagner CR. Journal of Molecular Biology 404 (4),

627-638.

2. E. coli histidine triad nucleotide binding protein 1 (ecHinT) is a catalytic regulator of D-

alanine dehydrogenase (DadA) activity in vivo (2011) Sanaa Bardaweel, Ghosh B, Chou

TF, Sadowsky MJ, Wagner CR. PloS one 6 (7), e20897.

3. Synthesis and Evaluation of Potential Inhibitors of Human and Escherichia coli Histidine Triad

Nucleotide Binding Proteins (2012) Sanaa Bardaweel, Brahma Ghosh, Carston R. Wagner,

Bioorganic & Medicinal Chemistry Letters 22 (1), 558-560.

4. Dynamic simulation of thermopneumatic micropumps for biomedical applications (2013)

Hamzeh Bardaweel and Sanaa Bardaweel. Microsystem technologies 19 (12), 2017-2024.

5. Complementary and alternative medicine utilization by a sample of infertile couples in Jordan

for infertility treatment: clinics-based survey (2013) Sanaa Bardaweel , Mayadah Shehadeh,

Ghadeer ARY Suaifan and Maria-Vanessa Z Kilani, BMC Complementary and Alternative

Medicine 13 (1), 35

6. An in vitro Based Investigation into the Cytotoxic Effects of D-amino Acids (2013) Sanaa

Bardaweel, Rana Abu-Dahab, and Nour F. Almomani. Acta Pharmaceutica 63 (4), 467-478.

7. D-serine in Neurobiology: CNS Neurotransmission and Neuromodulation (2014) Sanaa

Bardaweel, Muhammed Alzweiri and Aman Ishaqat. The Canadian Journal of Neurological

Sciences 41 (2), 164-176.

8. D-amino Acids: Prospects for New Therapeutic Agents (2014) Sanaa Bardaweel. Journal of

Medical and Bioengineering 3,195-198.

9. Alternative and antioxidant therapies utilization by a sample of infertile males in Jordan: a cross

sectional survey (2014) Sanaa Bardaweel. BMC Complementary and Alternative Medicine

14:244.

10. Antioxidant, antimicrobial and antiproliferative activities of Anthemis palestina essential oil

(2014) Sanaa Bardaweel, Khaled A. Tawaha, Mohammad M. Hudaib. BMC Complementary

Page 18 of 24

and Alternative Medicine 14:297.

11. Evaluation of antibacterial, antifungal, and anticancer activities of essential oils from six species

of Eucalyptus (2014) Sanaa Bardaweel, Mohammad Hudaib, Khaled Tawaha. Journal of

Essential Oil Bearing Plants. 17 (6), 1165 – 1174.12. Synergism and efficacy of some naturally occurring D-amino acids against clinically relevant

bacterial and fungal species (2014) Sanaa Bardaweel, Rula M. Darwish, Muhammed H.

Alzweiri and Yusuf M. Al-Hiari. Jordan Journal of Pharmaceutical Sciences. 7, No. 3, 2014

13. The development and application of novel IR and NMR-based model for the evaluation of

carminative effect of Artemisia Judaica L. Essential oil (2014) Muhammed Alzweiri, Ibrahim

M. Alrawashdeh, and Sanaa K. Bardaweel. International Journal of Analytical Chemistry.

Volume 2014, Article ID 627038, 10 pages.

14. Antimicrobial, Antioxidant and Free Radical Scavenging Activities of Essential Oils Extracted

from Six Eucalyptus Species (2015). Sanaa K. Bardaweel, Mohammad M. Hudaib, Khaled A.

Tawaha, Rasha M. Bashatwah. International Journal of Biological, Food, Veterinary and

Agricultural Engineering. Vol:9, 66-69.

15. Molecular modeling based approach, synthesis, and cytotoxic activity of novel benzoin

derivatives targeting phosphoinostide 3-kinase (PI3K) (2015). Dima A. Sabbah, Musaab Saada,

Sanaa Bardaweel, Reema Abu Khalaf, Kamal Sweidan, Ghassan Abu Sheikha, Heba Abdel

Halim, Jonathan L. Vennerstrom, Haizhen Zhong. Bioorganic & Medicinal Chemistry Letters.

25 3120–3124.

16. Studies on the In Vitro Antiproliferative, Antimicrobial, Antioxidant, and Acetylcholinesterase

Inhibition Activities Associated with Chrysanthemum coronarium Essential Oil (2015). Sanaa

K Bardaweel, Mohammad M Hudaib, Khaled A Tawaha, Rasha M Bashatwah. Evidence-Based

Complementary and Alternative Medicine.

17. Olive Oil-derived Oleocanthal as Potent Inhibitor of Mammalian Target of Rapamycin:

Biological Evaluation and Molecular Modeling Studies (2015). Mohammad A Khanfar · Sanaa

K Bardaweel · Mohamed R Akl · Khalid A El Sayed. Phytotherapy Research 08/2015; Page 19 of 24

DOI:10.1002/ptr.5434 ·

18. Synthesis of Novel 2,5-Disubstituted-1,3,4-Thiadiazoles Clubbed

1,2,4-Triazole, 1,3,4-Triazole, 1,3,4-Oxadiazole and Schiff Base as Potential

Antimicrobial and Antitumor Agents (2015). Nadjet Rezki, Amjad Mohammed Al-Yahyawi,

Sanaa Khaled Bardaweel, Fawzia Faleh Al-blewi , Mohamed R. Aouad. Molecules., 20,

16048-16067

19. Current knowledge, attitude, and patterns of oral contraceptives utilization among women in

Jordan (2015). Sanaa K. Bardaweel, Amal A. Akour and Maria-Vanessa Z. Kilani. BMC

Women's Health 15:117.

20. Fatty Acids Analysis, Antioxidant and Biological Activity of Fixed Oil of Annona muricata

L. Seeds (2016). Zaha A. Elagbar, Rajashri R. Naik, Ashok K. Shakya, and Sanaa K. Bardaweel. Journal of Chemistry, Volume 2016, Article ID 6948098, 6 pages.

21. Design, synthesis and evaluation of benzofuran-acetamide scaffolds potential anticonvulsant agent (2016). Ashok K. Shakya, Mehnaz Kamal, Vishal M. Balaramnavar, Sanaa K. Bardaweel, Rajashri R. Naik1,Anil K. Saxena, H. H. Siddiqui. Acta Pharmaceutica 66, 353–372.

22. Computer-aided design, synthesis, and biological evaluation of new indole-2-carboxamide derivatives as PI3Kα/EGFR inhibitors (2016). Kamal Sweidan, Dima A. Sabbah, Sanaa K. Bardaweel, Khadeja Abu Dush, Ghassan Abu Sheikha, Mohammad S. Mubarak. Bioorganic & Medicinal Chemistry Letters, 26, 2685–2690.

23. Computer-aided discovery of safe antimicrobial agents as potential enoyl acyl carrier protein reductase inhibitors (2016). Mohammad A Ghattas, Nermin A Eissa1, Sanaa K Bardaweel, Abdallah Abu Mellal and Noor Atatreh. Tropical Journal of Pharmaceutical Research 16 (2), 397-405.

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24. An Eco-Friendly Ultrasound-Assisted Synthesis of Novel Fluorinated Pyridinium Salts-Based Hydrazones and Antimicrobial and Antitumor Screening (2016). Nadjet Rezki, Salsabeel A. Sodies, Mohamed R. Aouad, Sanaa K. Bardaweel, Mosslim Messali. International Journal of Molecular Science, 2016, 17, 766.

25. Stability determination for cyclized 2,4- dinitrophenyl hydrazone derivative of glucose (2017)Muhammed Alzweiri, Sara Al-Marabeh, Sanaa K. Bardaweel , Rawhi Alfar and Yusuf M. Al-Hiari, Journal of Analytical Science and Technology, 8:9

26. Facile synthesis, characterization and cytotoxicity study of new 3-(indol-2-yl)bicyclotetrazatridecahexaens (2017). Kamal Sweidana Dima Sabbah, Sanaa Bardaweel, Ghassan Abu Sheikha, Tariq AlQirim, Hanadi Salih,Mohammad S. Mubarak and Wolfgang Voelter. Canadian Journal of

Chemistry 95: 858–862

27. Pharmacological Evaluation of Novel Isonicotinic carboxamide Derivatives as Potential Anti-hyperlipidemic and Antioxidant Agents (2017). Rana Abu Farha, Yasser Bustanji, Yusuf Al-Hiari, Sanaa K. Bardaweel, Tariq Al-Qirim, Ghassan Abu Sheikha, Rabab Albashiti. Arch. Pharm. Chem. Life Sci. 2017, 350, e1700024

28. Chemisorption of Carbon Dioxide by a Biodegradable Chitosan Oligosaccharide/DMSO Green Sorbent: Novel Organic Carbamato-Carbonato Bond Formation (2017) Abdussalam K. Qaroush, Khaleel I. Assaf, Sanaa K. Bardaweel, Ala’a Al-Khateeb, Fatima Alsoubani, Esraa Al-Ramahi, Mahmoud Masri, Thomas Brück, CarstenTroll, Bernhard Rieger, Ala’a F. Eftaiha, Green Chemistry, 19, 4305-4314

29. Structure-Based Drug Design: Synthesis, X-Ray Crystallography, and

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Biological Evaluation of N-Substituted-4-Hydroxy-2-Quinolone-3-Carboxamides as Potential PI3Kα Inhibitors. (2018) Dima A. Sabbah, Bayan Hishmah, Kamal Sweidan, Sanaa Bardaweel, Murad AlDamen, Haizhen A. Zhong, Reema Abu Khalaf, Ameerah Hasan Ibrahim, Tariq Al-Qirim, Ghassan Abu Sheikha, Mohammad S. Mubarak. Anticancer agents in Medicinal chemistry,263-276.

30. Design, synthesis, in-silico and in-vitro antimicrobial screenings of novel 1,2,4-triazoles carrying 1,2,3-triazole scaffold with lipophilic side chain tether (2017) Mohamed Reda Aouad, Mariem Mohammed Mayaba1, Arshi Naqvi1, Sanaa K. Bardaweel3, Fawzia Faleh Al-blewi1, Mouslim Messali, Nadjet Rezki. Chemistry Central Journal 11:17

31. Synthesis and structure-activity relationship exploration of some potent anti-cancer phenyl amidrazone derivatives (2018) Almeqdad Y. Habashneh, Mustafa M. El-Abadelah, Sanaa K Bardaweel and Mutasem O. Taha. Med Chem., 14. 1-10

32. Synthesis, Structural Elucidation of Aminoacetylenicoxyquinazoline and their Antiproliferative Activities. (2017) Zuhair A Muhi-eldeen, Bara Alani, Elham N Al-

Kaissi, Sanaa K Bardaweel, Mohammad Gattas , Tawfeeq Arafat. Der Pharma Chemica,

9(23):38-45.

33. Synthesis, characterization, and bioactivity of new bisamidrazone derivatives as possible anticancer agents. (2018) Malath A. Al-Qtaitat, Mustafa M. El-Abadelah,

Dima A. Sabbah, Sanaa Bardaweel, Kamal Sweidan, Salim S. Sabri, Mohammad S. Mubarak.

Medicinal Chemistry Research 27:1419–1431

34. Benzoin Schiff Bases: Design, Synthesis, and Biological Evaluationas Potential Antitumor Agents, (2018) Dima A. Sabbah, FatimaAl-Tarawneh, WamidhTalib, Kamal Sweidan, Sanaa Bardaweel, Eveen Al-Shalabia, Haizhen A. Zhong, Ghassan Abu Sheikha, Reema Abu Khalaf, Mohammad S.

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Mubarak Medicinal Chemistry, 14, 1-14

35. Impact of a pharmacist-provided information booklet on knowledge and attitudes towards oral

contraception among Jordanian women: an interventional study. (2017) Suha Al-Muhaissen &

Rand Hussein Amal Akour, Sanaa Bardaweel, Oriana Awwad. The European Journal of

Contraception & Reproductive Health Care. Volume 22, Issue 6.Page 459-464.

36. Identification of new pyridinium ionic liquids tagged with Schiff bases: Design, synthesis, in silico ADMET predictions and biological evaluations, (2018) Nadjet Rezki, Salsabeel A. Al-Sodies, Mouslim Messali, Sanaa K. Bardaweel, Pramod K. Sahud, Fawzia F. Al-blewi, Praveen K. Sahu, Mohamed R. Aouad. Journal of Molecular Liquids 264, 367–374

37. Discovery of potent polyphosphate kinase 1 (PPK1) inhibitors using structure‐based exploration of PPK1Pharmacophoric space coupled with docking analyses (2018) Rasha M Bashatwah, Mohammad A Khanfar, Sanaa K

Bardaweel. Journal of Molecular Recognition. e2726.

38. Design, synthesis, in-silico and in-vitro evaluation of di-cationic pyridinium ionic liquids as

potential anticancer scaffolds, (2018) Nadjet Rezki, Mouslim Messali, Salsabeel A Al-Sodies,

Arshi Naqvi, Sanaa K Bardaweel, Fawzia F Al-blewi, Mohamed R Aouad, H El Sayed. Journal

of Molecular Liquids. 265, 428–441

39. Impediments to Oral Contraceptives Utilization among Refugee Women in Camps, Jordan, (2018), Sanaa K. Bardaweel*, Amal A. Akour and Aseel ALkhawaldeh. Women &Health, in press

40. Glucose deprivation enhances the antiproliferative effects of oral hypoglycemic biguanides in different molecular subtypes of breast cancer: An in vitro study, (2018), Sanaa K. Bardaweel*, Husam A. AlSalamat, Shereen M. Aleidi, and Rasha M. Bashatwah, Acta Pharmaceutica, In press

41. Reactive Oxygen Species: The Dual Role in Physiological and Pathological Page 23 of 24

Conditions of the Human Body, (2018), Sanaa K. Bardaweel*, Mustafa Gul, Muhammad Alzweiri, Aman Ishaqat, Husam A. ALSalamat, and Rasha M. Bashatwah, The Eurasian Journal of Medicine, in Press

42. Chemical Composition, Antioxidant, Antimicrobial and Antiproliferative Activities of Essential Oil of Mentha spicata L. (Lamiaceae) from Algerian Saharan Atlas, (2018) Sanaa K. Bardaweel, Boulanouar Bakchiche , Husam A.

ALSalamat , Maria Rezzoug , Abdelaziz Gherib and Guido Flamini, BMC Complementary and

Alternative Medicine 18:201

CONTACT INFORMATION

Sanaa K. Bardaweel,  Ph.D.Associate Professor of Medicinal ChemistryDepartment of Pharmaceutical SciencesSchool of PharmacyUniversity of Jordan Amman 11942 JordanOffice #: 00962 5355000 Ext. 23318Cell Phone: 0777190831S.bardaweel@ju.edu.johttp://eacademic.ju.edu.jo/s.bardaweel/default.aspx

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