Washington’s Life Sciences An Overview

Chris E. Rivera, President

Biotechnology’s Potential – Cure our worst diseases!

Biotech therapies are helping improve the prognosis for cancer patients by increasing survival rates.

U.S. Five Year Relative Survival Relates for Selected Cancers

Source: National Cancer Institute, “SEER Cancer Statistics Review 1975–2006,” 2004. Available at http://www.seer.cancer.gov/.

Reduce Our Need on Foreign Oil

Potential reduction in US petroleum imports by 2022 could exceed $350 billion

Economic output generated by advanced biofuels could reach: $64.2 billion by 2016 $148.7 billion by 2022

Jobs created could reach: 94,000 direct jobs by 2016 190,000 direct jobs by 2022

Total jobs impact (direct and indirect) could reach: 383,000 in 2016 807,000 by 2022

Source: “U.S. Economic Impact of Advanced Biofuels Production: Perspectives to 2030.” Bio Economic Research Associates. February 2009.

Feed 9 Billion People

Average U.S. corn yields and kinds of corn, 1865 to 2004

Sources: (1) USDA-NASS Data 2005. (2) A. Forrest Troyer 2006. “Adaptedness and Heterosis in Corn and Mule Hybrids.” Crop Science 46:528-543 (2006).

Biotech crops are at the forefront of increasing agricultural yields. U.S. Department of Agriculture data on annual corn yields dramatically illustrate the extent to which crop improvements, via selective breeding and hybridization, led to large-scale yield increases from the 1960s through the mid-1990s, and how (starting in

1997) biotechnology has allowed the trend in yield gains to continue. Harnessing these biotech improvements globally is increasingly necessary to feed the expanding population.

WA’s Life Sciences Industry

33,519 directly employed 90,737 directly or indirectly

employed One of Washington’s largest jobs

sectors One of Washington’s fastest

growing sectors $10.4B in state GDP $6.6B in personal income Statewide industry – nearly 70

cities have a life science organization within its borders

Nearly 450 life science companies, research institutions and non-profit organizations

World class research, development & commercialization;

Oncology, immunology, infectious disease & regenerative medicine

Therapeutic ultrasound & AED’s discovered in WA

Nexus of Global Health Personalized Medicine - informatics,

genomics & health care IT Bio-agriculture, bio-fuels & veterinary

medicine

Economic Impact

Between 2001 – 08, jobs in WA’s life science sector outpaced the (U.S.) average nearly 2:1; Agriculture – 23% (1.9%) Drugs – 7.5% (2.3%) Devices – 4.6% (2%) Research – 57% (46%) Total – 31% (16%)

And, total private sector jobs 3:1 Total WA job change – 9.9% (3.5%)

Source: Battelle/BIO State Bioscience Initiatives; 2010

Nationally Competitive

One VC’s Opinion

“Seattle (WA) has, from my point of view, carved out its position as the No. 3 bioscience market in the U.S. behind Boston and the San Francisco Bay Area.”

Carl Weissman, Chairman and CEO of Accelerator, and Managing Director at OVP Venture Partners.

Supporting Life Sciences Sustainability

Mission: Innovation to Realization; supporting breakthrough discoveries that create better

health solutions Support and help grow Washington state’s life science ecosystem

Priorities: Commercialization & Translational research Capital Talent Policy Saving members $ millions

Goals: Increase awareness of the importance of the sector Increase awareness of the current and future economic impact Increase funding, capital and investment in the sector Strong policy that maintains and enhances our competiveness and growth Shine the global spotlight on Washington’s Life Sciences sector!

WBBA’s Membership

Independent, 501(c)(6) 100% funded by our more

than 450 dedicated members

More than 100 new members joined in 2011

One of the largest state life science associations in the US

2011 Survey results 90% - established new

relationships

75% - learned more about the industry

30% - saved money

Commercialization & Translational Research

Nearly 100 life science start-ups mentored by the WBBA to date

www.lifesciencestartup.com

Capital

WINGS – The Washington Medical Technology Angel Network

Launched in 2010 by WBBA to close early stage MedTech funding gap

86 opportunities screened to date

19 companies presented at 7 WINGS Investor Meetings

>$3M invested in 7 WA companies by WINGS*

WINGS Angels invested $2.1M

*Additional $1.2M invested via “friends” of WINGS

2 more in diligence

VIP (Venture Investment & Partnering) – Forum

WBBA hosts VC’s and multi-national strategic partners

Showcase for regional companies and researchers

5 Forums in 2011: BioWa (Japan), J&J*, Merck*, Takeda and Bayer Healthcare

>45 one-on-one meetings in 2011

Program expanded to include open, sponsored presentation by each VIP

Next VIP: Bristol-Myers Squibb, January 2012

Non-dilutive Capital

Advocating for NIH, DoD, NCI, etc. funding sustainability

LSDF sustainability

Talent

Focus: Recruitment, retention and development of talent

Career Center – launched 2010 9,000 on-line job searches 136,500 views of openings 50% increase over 2010

Lab to Leader Policy Priority – Higher Education (STEM)

Governor’s Higher Education Task Force Working to expand degrees &

certifications for students Discussions ongoing with BIO & CSBA

Networking 2012 Priority – Workforce development

Member Benefits

In 2011, our members purchased >$30 million in health care benefits, lab equipment, office supplies and much more

Nearly $5 million saved!

Nearly $500k returned through L&I retro program

2012 Event Calendar

Life Science Innovation Northwest

Largest life science collaboration conference on the West Coast

Largest & most diverse attendance ever! >10% of attendees from 14 countries, ex-US 70 presenting Northwest companies & organizations Hundreds of 1:1 meetings, Speed dating & Poster Alley Jim Greenwood & Steve Burrill - keynotes Expert Panels

CEO’s

Large multi-nationals

Global Health

Intellectual Property

Business Development

Raising Capital

Partnering

Much more!

Don’t miss LSINW – 2012

July 10 – 12Seattle, WA

Recommendations

“How can we ensure that the state remains strong in the life sciences?”

Engaged research institutions with active leadership

Available risk capital covering all stages of the business cycle

Workforce and talent pool Stable and supportive

business, tax and regulatory policies

Patience and long term perspective

“While Washington is an attractive place to live, we do need to be mindful that we are competing with states such as Massachusetts, California and New Jersey that offer outstanding career prospects for talented scientists and engineers.”

Thank You

Life Sciences Economic Impact

“Washington state’s research universities’ success in attracting NIH funding, along with that of local private research institutions, anchors our life sciences industry.”